CN108135938A - 基因修饰的抗第三方中央型记忆t细胞及其在免疫疗法中的用途 - Google Patents

基因修饰的抗第三方中央型记忆t细胞及其在免疫疗法中的用途 Download PDF

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CN108135938A
CN108135938A CN201680053580.8A CN201680053580A CN108135938A CN 108135938 A CN108135938 A CN 108135938A CN 201680053580 A CN201680053580 A CN 201680053580A CN 108135938 A CN108135938 A CN 108135938A
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cells
cell
virus
antigen
antigens
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Y.雷斯纳
N.奥-格瓦
E.奥普希
Y.埃德斯泰恩
R.吉德龙布多维斯基
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Yeda Research and Development Co Ltd
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CN201680053580.8A 2015-07-16 2016-07-14 基因修饰的抗第三方中央型记忆t细胞及其在免疫疗法中的用途 Pending CN108135938A (zh)

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US201562193207P 2015-07-16 2015-07-16
US201562193229P 2015-07-16 2015-07-16
US62/193229 2015-07-16
US62/193207 2015-07-16
PCT/IL2016/050775 WO2017009853A1 (en) 2015-07-16 2016-07-14 Genetically modified anti-third party central memory t cells and use of same in immunotherapy

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CN201680053579.5A Pending CN108025026A (zh) 2015-07-16 2016-07-14 抗第三方中央型记忆t细胞的用途
CN201680053580.8A Pending CN108135938A (zh) 2015-07-16 2016-07-14 基因修饰的抗第三方中央型记忆t细胞及其在免疫疗法中的用途

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CN201680053579.5A Pending CN108025026A (zh) 2015-07-16 2016-07-14 抗第三方中央型记忆t细胞的用途

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US (4) US10933124B2 (enExample)
EP (2) EP3322424B1 (enExample)
JP (1) JP7057748B2 (enExample)
CN (3) CN114457039B (enExample)
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WO2020248486A1 (zh) * 2019-06-13 2020-12-17 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
CN112969470A (zh) * 2018-09-10 2021-06-15 阿塔拉生物制药股份有限公司 用于扩增抗原特异性car-t细胞、组合物的方法及其相关用途
US11555178B2 (en) 2017-01-18 2023-01-17 Yeda Research And Development Co. Ltd. Genetically modified veto cells and use of same in immunotherapy
CN116096865A (zh) * 2020-02-28 2023-05-09 Ksq治疗公司 用于激活和扩增肿瘤浸润淋巴细胞的方法
CN116322717A (zh) * 2020-08-11 2023-06-23 耶达研究及发展有限公司 否决car-t细胞
US11844827B2 (en) 2015-07-16 2023-12-19 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
US12133866B2 (en) 2011-09-08 2024-11-05 Yeda Research And Development Co. Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment

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EP2365823B1 (en) 2008-10-30 2016-11-30 Yeda Research And Development Company Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
CN114081946A (zh) * 2014-03-12 2022-02-25 耶达研究与开发有限公司 降低系统性调节性t细胞水平或活性来治疗cns疾病和损伤
AU2017289879B2 (en) 2016-06-27 2023-04-20 Yeda Research And Development Co. Ltd. Veto cells generated from memory T cells
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
CN107573419A (zh) * 2017-01-24 2018-01-12 深圳市体内生物医药科技有限公司 一种增强t细胞抗肿瘤活性的核酸分子
CN107254489B (zh) * 2017-06-19 2021-06-18 河南省华隆生物技术有限公司 一种检测嵌合抗原受体或基因修饰的t细胞受体表达的方法和应用
SG11202007171PA (en) * 2018-02-02 2020-08-28 Univ Pennsylvania Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates
WO2019222762A1 (en) * 2018-05-18 2019-11-21 Children's National Medical Center Improved cell therapy compositions for hematopoietic stem cell transplant patients
CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
JP7650818B2 (ja) * 2019-04-26 2025-03-25 アロジーン セラピューティクス，インコーポレイテッド 同種ｃａｒ ｔ細胞を製造する方法
WO2021024264A2 (en) * 2019-08-06 2021-02-11 Yeda Research And Development Co. Ltd. Anti-viral central memory cd8+ veto cells in haploidentical stem cell transplantation
CN110628717B (zh) * 2019-10-28 2020-10-30 上海科医联创生物科技有限公司 一种浸润性t细胞的培养方法
WO2021090321A1 (en) * 2019-11-05 2021-05-14 Yeda Research And Development Co. Ltd. Use of veto cells in treatment of t cell mediated autoimmune diseases
CN114901801A (zh) * 2019-11-05 2022-08-12 耶达研究及发展有限公司 用于治疗镰状细胞病的数个否决细胞的用途
IL298693A (en) 2020-06-04 2023-02-01 Carisma Therapeutics Inc New structures for chimeric antigen receptors
US20240001142A1 (en) * 2020-10-07 2024-01-04 Board Of Regents, The University Of Texas System Induction by low dose radiation of cancer cell targets for cell-based or small molecule therapy

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