JP7057748B2 - 遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 - Google Patents

遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 Download PDF

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JP7057748B2
JP7057748B2 JP2018501339A JP2018501339A JP7057748B2 JP 7057748 B2 JP7057748 B2 JP 7057748B2 JP 2018501339 A JP2018501339 A JP 2018501339A JP 2018501339 A JP2018501339 A JP 2018501339A JP 7057748 B2 JP7057748 B2 JP 7057748B2
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cells
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antigen
tcm
receptor
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JP2018524987A5 (enExample
JP2018524987A (ja
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イェアー ライズナー，
ノガ オア－ゲヴァ，
エラン オフィア，
ヤキ アイデルシュタイン，
ブドヴスキー， ロテム ギドロン
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Yeda Research and Development Co Ltd
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JP2018501339A 2015-07-16 2016-07-14 遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 Active JP7057748B2 (ja)

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Application Number Priority Date Filing Date Title
US201562193229P 2015-07-16 2015-07-16
US201562193207P 2015-07-16 2015-07-16
US62/193,207 2015-07-16
US62/193,229 2015-07-16
PCT/IL2016/050775 WO2017009853A1 (en) 2015-07-16 2016-07-14 Genetically modified anti-third party central memory t cells and use of same in immunotherapy

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JP2018524987A JP2018524987A (ja) 2018-09-06
JP2018524987A5 JP2018524987A5 (enExample) 2019-08-29
JP7057748B2 true JP7057748B2 (ja) 2022-04-20

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US (4) US11179448B2 (enExample)
EP (2) EP3322425B1 (enExample)
JP (1) JP7057748B2 (enExample)
CN (3) CN108135938A (enExample)
AU (1) AU2016291825B2 (enExample)
CA (1) CA2991690A1 (enExample)
DK (1) DK3322425T3 (enExample)
ES (2) ES2946785T3 (enExample)
IL (1) IL256916B2 (enExample)
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EP2753351B1 (en) 2011-09-08 2017-06-21 Yeda Research and Development Co. Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
ES3040431T3 (en) * 2014-03-12 2025-10-31 Yeda Res & Dev Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
US11179448B2 (en) 2015-07-16 2021-11-23 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
KR102444170B1 (ko) 2016-06-27 2022-09-16 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 기억 t 세포로부터 생성된 베토 세포
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
IL268126B2 (en) 2017-01-18 2024-02-01 Yeda Res & Dev Genetically engineered Veto cells and their uses in immunotherapy
CN107573419A (zh) * 2017-01-24 2018-01-12 深圳市体内生物医药科技有限公司 一种增强t细胞抗肿瘤活性的核酸分子
CN107254489B (zh) * 2017-06-19 2021-06-18 河南省华隆生物技术有限公司 一种检测嵌合抗原受体或基因修饰的t细胞受体表达的方法和应用
JP7570231B2 (ja) * 2018-02-02 2024-10-23 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア キメラ抗原受容体を発現する改変された単球／マクロファージ／樹状細胞、ならびにタンパク質凝集物に関連する疾患および障害における使用
WO2019222762A1 (en) * 2018-05-18 2019-11-21 Children's National Medical Center Improved cell therapy compositions for hematopoietic stem cell transplant patients
EP4458419A3 (en) * 2018-09-10 2025-01-08 Atara Biotherapeutics, Inc. Methods for expanding antigen-specific car-t cells, compositions and uses related thereto
CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
WO2020219812A1 (en) * 2019-04-26 2020-10-29 Allogene Therapeutics, Inc. Methods of manufacturing allogeneic car t cells
CN110358734B (zh) 2019-06-13 2020-08-25 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
CN114466925A (zh) * 2019-08-06 2022-05-10 耶达研究及发展有限公司 单倍体相合的干细胞移植中的抗病毒中央型记忆cd8+反抑细胞
CN110628717B (zh) * 2019-10-28 2020-10-30 上海科医联创生物科技有限公司 一种浸润性t细胞的培养方法
CN115175688A (zh) * 2019-11-05 2022-10-11 耶达研究及发展有限公司 在数个t细胞介导的自身免疫性疾病的治疗中的数个否决细胞的用途
BR112022008700A2 (pt) * 2019-11-05 2022-07-19 Yeda Res & Dev Método para tratar ou prevenir uma doença falciforme, e, transplante de células hematopoiéticas imaturas e uma quantidade terapeuticamente eficaz de uma população isolada de células anti-terceiros não indutoras de doença do enxerto versus hospedeiro
CA3168932A1 (en) * 2020-02-28 2021-09-02 Micah BENSON Methods for activation and expansion of tumor infiltrating lymphocytes
EP4161536A4 (en) 2020-06-04 2024-08-14 Carisma Therapeutics Inc. Novel constructs for chimeric antigen receptors
CA3189051A1 (en) * 2020-08-11 2022-02-17 Yair Reisner Veto car-t cells
WO2022076743A1 (en) * 2020-10-07 2022-04-14 Board Of Regents, The University Of Texas System Induction by low dose radiation of cancer cell targets for cell-based or small molecule therapy

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