AU2016291825B2 - Genetically modified anti-third party central memory T cells and use of same in immunotherapy - Google Patents

Genetically modified anti-third party central memory T cells and use of same in immunotherapy Download PDF

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AU2016291825B2
AU2016291825B2 AU2016291825A AU2016291825A AU2016291825B2 AU 2016291825 B2 AU2016291825 B2 AU 2016291825B2 AU 2016291825 A AU2016291825 A AU 2016291825A AU 2016291825 A AU2016291825 A AU 2016291825A AU 2016291825 B2 AU2016291825 B2 AU 2016291825B2
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cells
cell
antigen
virus
tcm
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AU2016291825A1 (en
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Yaki Eidelstein
Rotem GIDRON BUDOVSKY
Eran Ophir
Noga Or-Geva
Yair Reisner
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Yeda Research and Development Co Ltd
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AU2016291825A 2015-07-16 2016-07-14 Genetically modified anti-third party central memory T cells and use of same in immunotherapy Active AU2016291825B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562193229P 2015-07-16 2015-07-16
US201562193207P 2015-07-16 2015-07-16
US62/193,229 2015-07-16
US62/193,207 2015-07-16
PCT/IL2016/050775 WO2017009853A1 (en) 2015-07-16 2016-07-14 Genetically modified anti-third party central memory t cells and use of same in immunotherapy

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AU2016291825A1 AU2016291825A1 (en) 2018-03-08
AU2016291825B2 true AU2016291825B2 (en) 2022-08-11

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US (4) US11179448B2 (enExample)
EP (2) EP3322425B1 (enExample)
JP (1) JP7057748B2 (enExample)
CN (3) CN108135938A (enExample)
AU (1) AU2016291825B2 (enExample)
CA (1) CA2991690A1 (enExample)
DK (1) DK3322425T3 (enExample)
ES (2) ES2946785T3 (enExample)
IL (1) IL256916B2 (enExample)
PL (2) PL3322425T3 (enExample)
WO (2) WO2017009853A1 (enExample)

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BR112014005355B1 (pt) 2011-09-08 2022-03-29 Yeda Research An Development Co., Ltd Células t de memória central anti-terceiro, métodos de produção e uso das mesmas em transplante e tratamento de doença
ES3040431T3 (en) * 2014-03-12 2025-10-31 Yeda Res & Dev Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
US11179448B2 (en) 2015-07-16 2021-11-23 Yeda Research And Development Co. Ltd. Genetically modified anti-third party central memory T cells and use of same in immunotherapy
WO2018002924A1 (en) 2016-06-27 2018-01-04 Yeda Research And Development Co. Ltd. Veto cells generated from memory t cells
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
IL268126B2 (en) 2017-01-18 2024-02-01 Yeda Res & Dev Genetically engineered Veto cells and their uses in immunotherapy
CN107573419A (zh) * 2017-01-24 2018-01-12 深圳市体内生物医药科技有限公司 一种增强t细胞抗肿瘤活性的核酸分子
CN107254489B (zh) * 2017-06-19 2021-06-18 河南省华隆生物技术有限公司 一种检测嵌合抗原受体或基因修饰的t细胞受体表达的方法和应用
AU2019215110B2 (en) * 2018-02-02 2024-07-25 The Trustees Of The University Of Pennsylvania Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates
US20210213066A1 (en) * 2018-05-18 2021-07-15 Children's National Medical Center Improved cell therapy compositions for hematopoietic stem cell transplant patients
KR20210061361A (ko) * 2018-09-10 2021-05-27 아타라 바이오테라퓨틱스 인크. 항원-특이적 car-t 세포를 확장하기 위한 방법, 이와 관련된 조성물 및 용도
CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
BR112021021349A2 (pt) * 2019-04-26 2022-02-01 Allogene Therapeutics Inc Métodos de fabricação de células car t alogênicas
CN110358734B (zh) * 2019-06-13 2020-08-25 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
JP2022543139A (ja) * 2019-08-06 2022-10-07 イェダ リサーチ アンド ディベロップメント カンパニー リミテッド ハプロタイプ一致幹細胞移植における抗ウイルスセントラルメモリーｃｄ８＋ベト細胞
CN110628717B (zh) * 2019-10-28 2020-10-30 上海科医联创生物科技有限公司 一种浸润性t细胞的培养方法
CA3160296A1 (en) * 2019-11-05 2021-05-14 Yeda Research And Development Co. Ltd. Use of veto cells for the treatment of sickle cell disease
IL292722A (en) * 2019-11-05 2022-07-01 Yeda res & development co ltd Use of veto cells in treatment of t cell mediated autoimmune diseases
CN116096865A (zh) * 2020-02-28 2023-05-09 Ksq治疗公司 用于激活和扩增肿瘤浸润淋巴细胞的方法
KR20230042691A (ko) 2020-06-04 2023-03-29 카리스마 테라퓨틱스 인코포레이티드 키메라 항원 수용체에 대한 신규한 작제물
CN116322717A (zh) * 2020-08-11 2023-06-23 耶达研究及发展有限公司 否决car-t细胞
WO2022076743A1 (en) * 2020-10-07 2022-04-14 Board Of Regents, The University Of Texas System Induction by low dose radiation of cancer cell targets for cell-based or small molecule therapy

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