CN107982237A - 一种盐酸索他洛尔制剂及其制备方法 - Google Patents
一种盐酸索他洛尔制剂及其制备方法 Download PDFInfo
- Publication number
- CN107982237A CN107982237A CN201810043035.1A CN201810043035A CN107982237A CN 107982237 A CN107982237 A CN 107982237A CN 201810043035 A CN201810043035 A CN 201810043035A CN 107982237 A CN107982237 A CN 107982237A
- Authority
- CN
- China
- Prior art keywords
- sotalol hydrochloride
- sotalol
- tablet
- label
- lubricant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (10)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810043035.1A CN107982237B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
CN201810692563.XA CN108785268B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810043035.1A CN107982237B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810692563.XA Division CN108785268B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN107982237A true CN107982237A (zh) | 2018-05-04 |
CN107982237B CN107982237B (zh) | 2018-11-23 |
Family
ID=62041194
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810043035.1A Expired - Fee Related CN107982237B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
CN201810692563.XA Active CN108785268B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810692563.XA Active CN108785268B (zh) | 2018-01-17 | 2018-01-17 | 一种盐酸索他洛尔制剂及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (2) | CN107982237B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111228229A (zh) * | 2020-03-31 | 2020-06-05 | 鲁南制药集团股份有限公司 | 一种盐酸索他洛尔片剂及其制备工艺 |
CN115429765A (zh) * | 2021-06-01 | 2022-12-06 | 山东新时代药业有限公司 | 一种盐酸索他洛尔缓释制剂及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000045807A1 (en) * | 1999-02-05 | 2000-08-10 | Alangudi Sankaranarayanan | Pharmaceutical composition comprising a combination of dextro- and laevo- isomers of sotalol |
US20060105044A1 (en) * | 2004-05-20 | 2006-05-18 | Singh Bramah N | Sustained release formulations of sotalol |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2039742A1 (en) * | 1990-04-23 | 1991-10-24 | Andrew B. Dennis | Tablet composition and method for problem pharmaceutical materials |
CN104825483B (zh) * | 2015-05-26 | 2017-10-13 | 青岛海之星生物科技有限公司 | 一种丙磺舒缓释片及制备方法 |
-
2018
- 2018-01-17 CN CN201810043035.1A patent/CN107982237B/zh not_active Expired - Fee Related
- 2018-01-17 CN CN201810692563.XA patent/CN108785268B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000045807A1 (en) * | 1999-02-05 | 2000-08-10 | Alangudi Sankaranarayanan | Pharmaceutical composition comprising a combination of dextro- and laevo- isomers of sotalol |
CN1328453A (zh) * | 1999-02-05 | 2001-12-26 | 托伦脱药品有限公司 | 含索他洛尔右旋和左旋异构体混合物的药物组合物 |
US20060105044A1 (en) * | 2004-05-20 | 2006-05-18 | Singh Bramah N | Sustained release formulations of sotalol |
US20170239199A1 (en) * | 2004-05-20 | 2017-08-24 | The Roshni Singh 2015 Trust | Methods of treatment using sustained release sotalol formulations |
Non-Patent Citations (2)
Title |
---|
AXEL ALT,ET AL: "Biopharmaceutical characterization of sotalol-containing oral immediate release drug products", 《EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS》 * |
姚静主编: "《药用辅料应用指南》", 31 August 2011, 中国医药科技出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111228229A (zh) * | 2020-03-31 | 2020-06-05 | 鲁南制药集团股份有限公司 | 一种盐酸索他洛尔片剂及其制备工艺 |
CN115429765A (zh) * | 2021-06-01 | 2022-12-06 | 山东新时代药业有限公司 | 一种盐酸索他洛尔缓释制剂及其制备方法 |
CN115429765B (zh) * | 2021-06-01 | 2024-03-15 | 山东新时代药业有限公司 | 一种盐酸索他洛尔缓释制剂及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN108785268B (zh) | 2021-05-28 |
CN107982237B (zh) | 2018-11-23 |
CN108785268A (zh) | 2018-11-13 |
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Legal Events
Date | Code | Title | Description |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: An Ning Inventor after: Li Mei Inventor before: Li Mei |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20181016 Address after: 719000 Yulin Xingyuan Hospital, Yuyang District, Yulin, Shaanxi 33 Applicant after: An Ning Address before: 315040 international road B 1209, 586 Jiangnan Road, hi tech Zone, Ningbo, Zhejiang, China, 95 Applicant before: Ningbo Mengman Biological Technology Co. Ltd. |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20181123 Termination date: 20210117 |