CN107921106B - Wt1抗原肽和免疫调节剂的组合用途 - Google Patents

Wt1抗原肽和免疫调节剂的组合用途 Download PDF

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Publication number
CN107921106B
CN107921106B CN201680042322.XA CN201680042322A CN107921106B CN 107921106 B CN107921106 B CN 107921106B CN 201680042322 A CN201680042322 A CN 201680042322A CN 107921106 B CN107921106 B CN 107921106B
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cancer
peptide
seq
pharmaceutically acceptable
pharmaceutical composition
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Chinese (zh)
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CN107921106A (zh
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高须秀夫
中村惠弥
后藤正志
杉边奈津子
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International Institute of Cancer Immunology Inc
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Sumitomo Pharmaceuticals Co Ltd
Sumitomo Dainippon Pharma Co Ltd
International Institute of Cancer Immunology Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN201680042322.XA 2015-05-20 2016-05-19 Wt1抗原肽和免疫调节剂的组合用途 Active CN107921106B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015-103145 2015-05-20
JP2015103145 2015-05-20
PCT/JP2016/064923 WO2016186177A1 (ja) 2015-05-20 2016-05-19 Ｗｔ１抗原ペプチドおよび免疫調節剤の併用

Publications (2)

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CN107921106A CN107921106A (zh) 2018-04-17
CN107921106B true CN107921106B (zh) 2023-09-08

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US (2) US20180140691A1 (enExample)
EP (1) EP3299028B1 (enExample)
JP (4) JP6515182B2 (enExample)
CN (1) CN107921106B (enExample)
CA (1) CA2986367A1 (enExample)
ES (1) ES2993462T3 (enExample)
WO (1) WO2016186177A1 (enExample)

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RS63561B1 (sr) 2015-11-20 2022-10-31 Memorial Sloan Kettering Cancer Center Kompozicija za lečenje raka
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
EP3549957A4 (en) * 2016-11-30 2020-08-05 Sumitomo Dainippon Pharma Co., Ltd. AUXILIARY PEPTIDE WT1, AND COMBINATION OF DUDIT PEPTIDE AND CONJUGATE PEPTIDE ANTIGENIC FOR CANCER
JP7250677B2 (ja) 2016-12-22 2023-04-03 キュー バイオファーマ， インコーポレイテッド Ｔ細胞調節多量体ポリペプチド及びその使用方法
MY192920A (en) * 2017-03-15 2022-09-15 Cancer Res Malaysia Immunogenic peptide composition
WO2018201090A1 (en) 2017-04-28 2018-11-01 Exicure, Inc. Synthesis of spherical nucleic acids using lipophilic moieties
AU2018277545B2 (en) 2017-05-31 2025-05-15 Stcube & Co., Inc. Methods of treating cancer using antibodies and molecules that immunospecifically bind to BTN1A1
KR20200044899A (ko) * 2017-08-28 2020-04-29 브리스톨-마이어스 스큅 컴퍼니 암의 치료 및 진단을 위한 tim-3 길항제
EP3692144A1 (en) * 2017-10-05 2020-08-12 Fulcrum Therapeutics, Inc. Use of p38 inhibitors to reduce expression of dux4
KR102184377B1 (ko) * 2018-02-19 2020-11-30 고려대학교 산학협력단 열충격단백질의 에피토프를 포함하는 백신 및 이의 용도
JP7162675B2 (ja) 2018-09-28 2022-10-28 住友ファーマ株式会社 注射用組成物
AU2019352354B2 (en) * 2018-10-05 2025-07-03 International Institute Of Cancer Immunology, Inc. Prophylactic or therapeutic drug for benign tumor
KR20220010712A (ko) * 2019-04-10 2022-01-26 에스엘에스지 리미티드 엘엘씨 Wt1-양성 암을 치료하기 위한 다가 면역요법 조성물 및 사용 방법
WO2021021924A1 (en) * 2019-07-29 2021-02-04 Huang Cai Gu Formulation of antibody based drugs for treating lung cancer by inhalation
WO2021117771A1 (ja) 2019-12-10 2021-06-17 大日本住友製薬株式会社 ペプチドエマルション製剤の調製方法
CA3161364A1 (en) * 2019-12-24 2021-07-01 Carl WALKEY Combination therapy using an il-2 receptor agonist and an immune checkpoint inhibitor
CA3169949A1 (en) * 2020-05-12 2021-11-18 Cue Biopharma, Inc. Multimeric t-cell modulatory polypeptides and methods of use thereof
MX2022014249A (es) * 2020-05-12 2023-02-22 Sumitomo Pharma Co Ltd Composición farmacéutica para tratar el cáncer.
KR20230009391A (ko) * 2020-05-12 2023-01-17 주식회사 엘지화학 다량체 t-세포 조절 폴리펩타이드 및 이의 사용 방법
WO2021231405A1 (en) * 2020-05-12 2021-11-18 Board Of Regents, The University Of Texas System Methods for treating glioblastoma
CN111647066B (zh) * 2020-07-01 2020-12-18 维肽瀛(上海)生物技术有限公司 Wt1多肽肿瘤抑制剂
JPWO2022030631A1 (enExample) * 2020-08-07 2022-02-10
EP4313046A1 (en) * 2021-03-31 2024-02-07 Celleron Therapeutics Limited Vaccine adjuvant
CN117838860B (zh) * 2023-11-27 2025-03-14 四川大学 一种抑制周围神经侵袭的药物、药物组合物、联合用药物
CN120463819A (zh) * 2024-11-18 2025-08-12 北京宝易生物技术有限公司 疫苗稀释液制备方法和应用

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CN103830211A (zh) * 2012-11-27 2014-06-04 上海曼克尔瑞生物医药技术有限公司 一种β-catenin蛋白抑制剂-姜黄素在肝癌治疗方面的应用
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WO2014134165A1 (en) * 2013-02-26 2014-09-04 Memorial Sloan-Kettering Cancer Center Compositions and methods for immunotherapy
WO2014157692A1 (ja) * 2013-03-29 2014-10-02 大日本住友製薬株式会社 Ｗｔ１抗原ペプチドコンジュゲートワクチン

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Also Published As

Publication number Publication date
WO2016186177A1 (ja) 2016-11-24
CA2986367A1 (en) 2016-11-24
CN107921106A (zh) 2018-04-17
JP7253210B2 (ja) 2023-04-06
JP2020075934A (ja) 2020-05-21
HK1248546A1 (zh) 2018-10-19
JPWO2016186177A1 (ja) 2018-04-12
JP6515182B2 (ja) 2019-05-15
US20240293521A1 (en) 2024-09-05
EP3299028B1 (en) 2024-10-30
EP3299028A1 (en) 2018-03-28
US20180140691A1 (en) 2018-05-24
JP6956967B2 (ja) 2021-11-02
HK1250213A1 (en) 2018-12-07
JP2019135251A (ja) 2019-08-15
JP2022000454A (ja) 2022-01-04
EP3299028A4 (en) 2019-02-27
JP6713160B2 (ja) 2020-06-24
ES2993462T3 (en) 2024-12-30

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