CN107823131A - 用于口服的溶液 - Google Patents
用于口服的溶液 Download PDFInfo
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- CN107823131A CN107823131A CN201711285346.0A CN201711285346A CN107823131A CN 107823131 A CN107823131 A CN 107823131A CN 201711285346 A CN201711285346 A CN 201711285346A CN 107823131 A CN107823131 A CN 107823131A
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- Prior art keywords
- acid
- solution
- compound
- oral solution
- glycine
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- 229940100688 oral solution Drugs 0.000 title claims abstract description 65
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 94
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 42
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 40
- -1 glycolic Chemical compound 0.000 claims abstract description 39
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 37
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 34
- 239000004310 lactic acid Substances 0.000 claims abstract description 34
- 150000003839 salts Chemical class 0.000 claims abstract description 34
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 32
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims abstract description 20
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims abstract description 18
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims abstract description 18
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000001630 malic acid Substances 0.000 claims abstract description 17
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| US201161548859P | 2011-10-19 | 2011-10-19 | |
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| CN201280051524.2A CN103889426A (zh) | 2011-10-19 | 2012-10-19 | 用于口服的溶液 |
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| CN201280051524.2A Division CN103889426A (zh) | 2011-10-19 | 2012-10-19 | 用于口服的溶液 |
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| CN107823131A true CN107823131A (zh) | 2018-03-23 |
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| CN201280051524.2A Pending CN103889426A (zh) | 2011-10-19 | 2012-10-19 | 用于口服的溶液 |
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| CN201280051524.2A Pending CN103889426A (zh) | 2011-10-19 | 2012-10-19 | 用于口服的溶液 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115192548A (zh) * | 2021-04-13 | 2022-10-18 | 上海博志研新药物技术有限公司 | 一种布瑞哌唑口溶膜组合物、其制备方法及应用 |
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| JP6203682B2 (ja) * | 2013-07-10 | 2017-09-27 | 共和薬品工業株式会社 | アリピプラゾール含有水性液剤 |
| RU2633635C1 (ru) * | 2016-06-29 | 2017-10-16 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| WO2017095266A1 (ru) * | 2015-12-01 | 2017-06-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения (варианты) |
| WO2017095265A1 (ru) * | 2015-12-01 | 2017-06-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| RU2627423C1 (ru) * | 2016-06-29 | 2017-08-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Фармацевтическая композиция для лечения инфекционно-воспалительных заболеваний местного применения и способ ее получения и применения |
| JP6786240B2 (ja) * | 2016-03-31 | 2020-11-18 | 小林製薬株式会社 | 粘性経口組成物 |
| US11013702B2 (en) * | 2017-10-10 | 2021-05-25 | Vertice Pharma, Llc | Midodrine hydrochloride oral solution and uses thereof |
| JPWO2021029020A1 (https=) * | 2019-08-13 | 2021-02-18 | ||
| JP2021115288A (ja) * | 2020-01-28 | 2021-08-10 | 青葉化成株式会社 | 液状組成物および液状医療材料 |
| CA3184420A1 (en) | 2020-06-30 | 2022-01-06 | Mark C. Faulkner | Compositions and methods for treatment of vaginal infections |
| US20210401879A1 (en) * | 2020-06-30 | 2021-12-30 | Vireo Systems, Inc. | Compositions for controlling odor and itch and methods of and devices for administering same |
| CN115414322A (zh) * | 2022-07-05 | 2022-12-02 | 杭州民生药物研究院有限公司 | 一种富马酸卢帕他定口服液体制剂及其制备工艺 |
| CN116966140A (zh) * | 2023-08-18 | 2023-10-31 | 四川阿赛斯生物科技有限公司 | 一种含有布瑞哌唑的口服溶液及其制备方法 |
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