CN107669564A

CN107669564A - It is a kind of that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging

Info

Publication number: CN107669564A
Application number: CN201711162611.6A
Authority: CN
Inventors: 江少卿
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-11-21
Filing date: 2017-11-21
Publication date: 2018-02-09
Anticipated expiration: 2037-11-21
Also published as: CN107669564B

Abstract

Present invention offer is a kind of to have reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, and it includes component A, B component and component C；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, Fructus Sechii edulis extract, spikemoss extract；The B component is oligopeptides；One or more of the wherein described oligopeptides in oligopeptides 1, oligopeptides 2, oligopeptides 3, oligopeptides 4, oligopeptides 5, oligopeptides 6, oligopeptides 10, Matrixyl 3, palmityl tripeptides 1, palmityl tripeptides 5, palmityl tetrapeptide 3, nutmeg pentapeptide 11, acetyl group tetrapeptide 5, acetyl group pentapeptide 1, acetyl group hexapeptide 8, acetyl group dipeptides 1；The component C is cosmetic and cosmetic base.

Description

It is a kind of that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging

Technical field

The present invention relates to cosmetic technical field, in particular it relates to it is a kind of have reparative regeneration, replenishing water and preserving moisture, The skin care compositions of anti-aging.

Background technology

The bad environmental factor of change and Long Term Contact due to the age, so the outward appearance of skin, physical characteristic and physiology Function changes in a variety of ways, and most noticeable change includes fine rule and wrinkle increases, flexibility missing, sagging increase, are solid Sense missing, the uniformity of color and luster missing, surface texture are coarse and the colouring agent of plaque-like is calm.Less obvious but measurable conduct Skin aging occurs or the change of experience chronic environmental insult includes the general decline of cell and organizational vitality, cellular replication rate Reduce, SkBF slows down, moisture is reduced, error accumulation structurally and functionally and skin self are rebuild and the ability of reparation Decline.Above-mentioned outward appearance and many changes functionally be due to the outer skin of skin change and internal layer water shortage caused by, And other change is as caused by the change of intradermal.When skin lesion occurs, many natural and complicated biochemical mechanisms Begin attempt to repair this infringement.

The increase of other operating pressure, how skin care pays close attention to problem as the vast people to like to be beautiful.Facial mask, it is shield A classification in skin product.Its most basic and most important purpose is to make up makeup removing and the still insufficient cleaning that washes one's face, Other essential ingredients are coordinated to realize other maintenance functions, such as replenishing water and preserving moisture, whitening and anti-aging, equilibrium oil on this basis Fat etc..

Although skin care item a great variety in the market, quality is uneven, and it is not that the good and the bad is also presented in effect.Some contain There is the product of lead, mercury or hormone, can not only play a part of skin care, on the contrary serious threat skin health；Also some are protected Skin product water content is larger, or containing alkalescent composition, contacted for a long time with skin can be caused due to excessive infiltration skin edema and Allergic phenomena.

Therefore, in view of the above-mentioned problems, the present invention provides a kind of skin care with reparative regeneration, replenishing water and preserving moisture, anti-aging Composition, it has potent purification flesh bottom, and nutrition is moistened, and Cucumber Extract, activates Skin Cell and reproducibility, maintains pore salubrious With accelerating wound healing and tissue repair, desalinate microgroove, the effect of replenishing water and preserving moisture and anti-anaphylaxis antiallergic.

The content of the invention

In order to solve the above problems, first aspect present invention provides a kind of with reparative regeneration, replenishing water and preserving moisture, anti-aging Skin care compositions, it includes component A, B component and component C；The component A is dendrobium candidum extract, aloe extract, Buddhist Hand mandarin orange extract, Gotu Kola P.E, Fructus Sechii edulis extract, spikemoss extract；The B component is oligopeptides；Wherein described oligopeptides Selected from oligopeptides -1, oligopeptides -2, oligopeptides -3, oligopeptides -4, oligopeptides -5, oligopeptides -6, oligopeptides -10, Matrixyl -3, palmityl three Peptide -1, palmityl tripeptides -5, palmityl tetrapeptide -3, nutmeg pentapeptide -11, acetyl group tetrapeptide -5, acetyl group pentapeptide -1, acetyl group One or more in hexapeptide -8, acetyl group dipeptides -1；The component C is cosmetic and cosmetic base.

In one embodiment, dendrobium candidum extract described in the component A and the aloe extract, the Buddhist Hand mandarin orange extract, the Gotu Kola P.E, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are (0.2-1)： (3-8)：(0.3-0.7)：(1-3)：(0.5-2)：(0.3-1).

In one embodiment, dendrobium candidum extract described in the component A and the aloe extract, the Buddhist Hand mandarin orange extract, the Gotu Kola P.E, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7： 0.5：1.2：1.1：0.7.

In one embodiment, oligopeptides described in the B component be oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide - 1。

In one embodiment, the oligopeptides -1 in the oligopeptides and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：(0.5-1.2)：(0.2-0.7).

In one embodiment, component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, delayed The 2%-10% of the weight of the skin care compositions of aging.

In one embodiment, the weight ratio of the component A and the B component is (5-12)：1.

In one embodiment, in the component C cosmetic include modification of chitosan, surfactant, essence, One or more in colouring agent.

In one embodiment, it is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging to be applied to Facial mask, eye cream, face cream, essence, mildy wash, stoste, toner, emulsion, emulsifiable paste, hydrosol, sun screen or BB frosts.

Second aspect of the present invention provide it is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions system Preparation Method, comprise the following steps：

(1) cosmetic in component C and cosmetic base are added in stirring container, is warming up to 78-80 DEG C, insulation 20min, it is cooled to 35-40 DEG C；

(2) component A dendrobium candidum extract, aloe extract, bergamot extract, centella are added into step (1) Extract, Fructus Sechii edulis extract, spikemoss extract, 10-15min is stirred, is well mixed material；

(3) B component oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1 are added into step (2), stirs 10-15min, Filtering, discharge, stand；Detect qualified rear packaging, storage.

The above-mentioned of the application and other features, aspect and advantage is more readily understood with reference to described further below.

Embodiment

Participate in the election of the detailed description of the invention below for being preferable to carry out method and including embodiment this hair can be more easily understood Bright content.Unless otherwise defined, all technologies used herein and scientific terminology have common with art of the present invention The identical implication that technical staff is generally understood that.When contradiction be present, the definition in this specification is defined.

As used herein term " by ... prepare " it is synonymous with "comprising".Term "comprising" used herein, " comprising ", " having ", " containing " or its any other deformation, it is intended that cover including for non-exclusionism.For example, the combination comprising listed elements Thing, step, method, product or device are not necessarily limited to those key elements, but can include not expressly listed other key elements or Such a composition, step, method, product or the intrinsic key element of device.

Conjunction " Consists of " excludes any key element do not pointed out, step or component.If be used in claim, this Phrase will make claim be closed, it is not included the material in addition to the material of those descriptions, but relative normal Except rule impurity.When being rather than immediately following in the clause that phrase " Consists of " appears in claim main body after theme, It is only limited to the key element described in the clause；Other key elements are not excluded outside the claim as entirety.

Equivalent, concentration or other values or parameter are excellent with scope, preferred scope or a series of upper limit preferred values and lower limit During the Range Representation that choosing value limits, this, which is appreciated that, specifically discloses by any range limit or preferred value and any scope All scopes that any pairing of lower limit or preferred value is formed, regardless of whether the scope separately discloses.For example, when open During scope " 1 to 5 ", described scope should be interpreted as including scope " 1 to 4 ", " 1 to 3 ", " 1 to 2 ", " 1 to 2 and 4 to 5 ", " 1 to 3 and 5 " etc..When number range is described herein, unless otherwise indicated, otherwise the scope is intended to include its end Value and all integers and fraction within the range.

Singulative includes plural number and object is discussed, unless the context clearly dictates otherwise." optional " or it is " any It is a kind of " refer to that the item that describes thereafter or event may or may not occur, and the description include situation that event occurs and The situation that event does not occur.

Approximate term in specification and claims is used for modifying quantity, and it is specific to represent that the present invention is not limited to this Quantity, include the part of the amendment of the acceptable change without cause related basic function close to the quantity.Phase Answer, modify a numerical value with " about ", " about " etc., mean that the invention is not restricted to the exact numerical.It is approximate in some examples Term likely corresponds to the precision of the instrument of measured value.In present specification and claims, scope limits can be with Combine and/or exchange, these scopes include all subranges contained therebetween if not stated otherwise.

In addition, indefinite article " one kind " before key element of the present invention or component and "one" to key element or the quantitative requirement of component (i.e. occurrence number) unrestriction.Therefore "one" or " one kind " should be read as including one or at least one, and odd number The key element or component of form also include plural form, unless the obvious purport of the quantity refers to singulative.

" polymer " means by the polymerizable compound prepared by the monomer that polymerize identical or different type.Generic term " polymer " includes term " homopolymer ", " copolymer ", " terpolymer " and " EVA ".

" EVA " means the polymer prepared by polymerizeing at least two different monomers.Generic term " EVA " includes (its is general with term " terpolymer " for term " copolymer " (its typically to refer to the polymer prepared by two kinds of different monomers) To refer to the polymer prepared by three kinds of different monomers)." blend " means that two or more polymer passes through physics Or the polymer that the method for chemistry is mixed and formed jointly.

In one embodiment, dendrobium candidum extract described in the component A and the aloe extract, the Buddhist Hand mandarin orange extract, the Gotu Kola P.E, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are (0.2-1)： (3-8)：(0.3-0.7)：(1-3)：(0.5-2)：(0.3-1)；Preferably, dendrobium candidum extract described in the component A with The aloe extract, the bergamot extract, the Gotu Kola P.E, the Fructus Sechii edulis extract, the Selaginella tamariscina carry The weight ratio for taking thing is 0.6：7：0.5：1.2：1.1：0.7.

Dendrobium candidum

Dendrobium candidum is orchid dendrobium candidum Dendrobium officinale Kimuraet Migo stem.Taste It is sweet, cold nature.Mainly containing alkaloid, Coumarins compound, polysaccharide compound, luxuriant and rich with fragrance class compound, Bibenzyl compound, times Half terpenoid, steroidal glycosides class compound.Exempt from nourishing the stomach of promoting the production of body fluid, nourishing Yin and clearing heat, moistening lung kidney-nourishing, the strong waist of improving eyesight, enhancing Epidemic disease power, clearing, antineoplastic action.

The extracting method of dendrobium candidum extract is as follows：

Dendrobium candidum is pulverized, 30 mesh powder material after sieving, it is that 85% ethanol mixes then to add mass fraction Close uniform, be heated to 70 DEG C, flow back degreasing 1.0h, discards residue, dry material, is then well mixed with water, is warming up to 95 DEG C, water-bath refluxing extraction 60min, filtered after being cooled to room temperature, discard residue and obtain material, be subsequently added into absolute ethyl alcohol, shake up, Refrigeration is stood overnight, and then centrifuges 20min in 4000r/min, and abandoning supernatant obtains material, and finally plus absolute ethyl alcohol washs 2 Secondary, centrifugation abandoning supernatant obtains material, then by dry materials, is cooled to room temperature and obtains dendrobium candidum extract.

Dendrobium candidum extract has that moistening effect is good, can desalinate microgroove, lasting moisturizing, repairs the work(such as impaired skin quality Effect.

Aloe

Aloe is Liliaceae perennial evergreen herbaceous plant Aloevera, nature and flavor：Hardship, tremble with fear.Aloe extract has sterilization Effect, antiinflammatory action moisten beautification function, letting out effect under stomach invigorating, cardiac stimulant promoting blood circulation effect, are immunized and palingenesis, it is immune with it is anti- Function of tumor, detoxication, anti-aging effects, analgesia, sedation, anti-sunlight function.

The extracting method of aloe extract is as follows：

The ripe Chinese aloe leaf of selection cleans peeling, carries out ultraviolet sterilization 10 minutes, is milled to starch, and adds in slurries The polyphenoils entered is 4-6 ‰, ethanol 10-15 ‰, is put into high speed separator and carries out separation of solid and liquid, and temperature is at 4-6 DEG C, mistake Filter out and carry out the water that solid adds 10 times, boiled 60-90 minutes, take filtrate, by the filtrate of first time and secondary filtrate Mixing, is concentrated under reduced pressure into dry, obtains aloe extract.

The effect of aloe, which is embodied in, promotes wound healing, immunological regulation, anti-oxidant, antibacterial, antiviral etc..

Bergamot

Buddha's hand (scientific name:Citrus medica L.var.sarcodactylis Swingle):For rutaceae Buddha's hand Fruit.Fruit each carpel separation in maturation, form the fruit lobe of elongate curved, shape such as finger, therefore named Buddha's hand.Buddha's hand also known as nine Pawl wood, the five fingers tangerine, bergamot.For main product in the Buddha's hand of the provinces such as Fujian Guangdong, river, Jiangsu and Zhejiang Provinces, wherein Jinhua, Zhejiang Buddha's hand is the most famous, is claimed It is refined to claim " gold bergamot " for " the celestial product in fruit, the strange grass of world ".Major function：Liver-smoothing, qi-regulating, and stomach and alleviating pain.For liver stomach Qi It is stagnant, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, deficiency of food vomiting.Main component is terpenes, sesquiterpene and higher alcohols, aldehydes, ketone Class, esters etc., its main bacteria to triggering acne, gram-positive bacteria have good inhibiting effect.

The extracting method of bergamot extract is as follows：

Fresh bergamot is soaked in distilled water, taken out after heating water bath 5-15min, the temperature of heating water bath is 50- 70 DEG C, take pericarp standby after being rinsed with distilled water, as pretreated bergamot pericarp；Then squeezed, squeezed Distilled water is sprayed into journey, the quality of the bergamot pericarp is 4 with the distilled water mass ratio sprayed into:1, the Buddha's hand after being squeezed Mandarin orange pericarp and eluent；Filtrate and filter residue are filtrated to get, and filter residue is washed to obtain cleaning solution, by obtained filtrate and is washed Wash liquid to mix and centrifuge, obtain being layered liquid after standing, collect the oil phase part in the layering liquid, as bergamot extracts Thing.

Centella

Centella (scientific name：Centella asiatica (L.) Urban), perennial herb, stem is crawled, elongated, raw on section Root.Alias collapse jorum, lack bowl grass, membranaceous marshmarigold herb, Gotu Kola, blood clam shell grass, cricket shell grass, centella asiatica, 18 lack, line grass, ground wire are careless, Husband's root, certain herbaceous plants with big flowers Penglai, chipping bowl, bowl of begging for food, Chinese bush cherry is careless, big membranaceous marshmarigold herb, native asarum, money chisel mouth, horseshoe crab Gui grass, BIANDIXIANG, oil lamp Dish, ox bath dish, bitter cress, wineglass dish, Hydrocotyle sibthorpioides lam.Var.Batvachium(Hand.- Mazz.) et shan, obcordate christia herb, duckweed, wild coltsfoot dish, interwined dragon grass, connect successively, the great Ye injury of the tissues Grass, Hu Guacao, landing plum blossom.Major function：It is clearing heat and detoxicating, it is inducing diuresis and reducing edema.

Gotu Kola P.E can compact epidermis and corium coupling part, skin can be made to limber up, help promotes skin corium Middle collagen is formed, and has the effect for making skin compact.Also assist in impaired organization healing and consolidation skin.Table can be promoted Close connection between skin and corium, and can suppress the increase of adipocyte, prevent hydroderma, obesity occur.

The extracting method of Gotu Kola P.E：

Centella be crushed into 30 mesh sieves 85% ethanol heating extraction, feed liquid mass volume ratio 1:50 (w/v), heating To 60 DEG C, ultrasonic assistant extraction, ultrasonic power 320W, twice, each 1.5h merges extraction filtrate, and said extracted is filtered for extraction Liquid is filtered with diatomite filter cake, and gained filtrate enters macroporous absorbent resin, and resin to the efflux after distilled water cleaning absorption is in nothing Color pellucidity, then 85% ethanol elution with 3 times of column volumes, collect eluent；Macroreticular resin D-101；Gained Eluent is concentrated under reduced pressure into the 1/6 of original volume, filters removal precipitation and obtains filtrate, carries out ultrafiltration desalination, milipore filter retention molecule Measure as 5K dalton, ultrafiltration pressure 8psi, obtain ultrafiltration retention concentrate, freeze-drying, obtain Gotu Kola P.E.

Chocho

Chocho (Sechiumedule (Jacq.) Swatz.) is that Curcurbitaceae chocho belongs to perennial climbing herb plant Fruit, originate in America Mexico, alias fist melon, 10000 years melons, rod melon etc., the tender crisp succulence of chocho, containing than general vegetables Much higher potassium and zinc, and VB, VC and various trace elements are rich in, it is a kind of health-care vegetable being loved by people, and The preferable health food of zinc-deficiency children.With qi-regulating with, the effect of soothing the liver cough-relieving, it is suitable for indigestion, inflatable uncomfortable in chest, vomits Tell, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach and tracheitis cough ant phlegm person are eaten.Polysaccharide, polyphenol and Flavonoid substances content in chocho is rich Richness, such material have the effect of preferable whitening, anti-ageing, anti-oxidant etc. for the skin of people, also have well to skin Skin whitening, moisturizing moisturizing effect, long-term use can make skin recover health status white touched with red, that water profit is full.

The extracting method of Fructus Sechii edulis extract：

Chocho is cleaned and is cut into strip and steeps the 0.5h in distilled water, after picking up naturally dry, frost, and it is dry in freezing It is dried, crushes in dry machine, it is standby crosses 80 mesh sieves.In the 250mL three-necked flasks equipped with condenser pipe, load a certain amount of Buddhist Hand melon powder, is placed in ultrasound reactor, according to concentration of alcohol 69%, 71 DEG C of ultrasonic temperature, liquid ratio 25mL/g, it is ultrasonic when Between 30min condition chocho is extracted, concentrate, obtain Fructus Sechii edulis extract.

Selaginella tamariscina

Selaginella tamariscina English name (Selaginella tamariscina (Beauv.) Spring) or hot shape Selaginella tamariscina Selaginella Puluinata (Hook.et Grev.) drying herb.Alias is Chinese juniper wood, tackles all problems at once, be tiger pawl, long-living Grass, pulchritudinous clubmoss herb, nine dead whorlleaf stonecrop herbs, tumbleweed.It is commonly used to control hemoptysis, spits blood, has blood in stool, prolapse of the anus, menorrhalgia, uterine hemorrhage, closing Through, rheumatalgia, traumatic injury, traumatism and bleeding, flu, bleeding from five sense organs or subcutaneous tissue, the disease such as metrorrhagia.The anti-inflammatory on baby's navel tripe is applied with Selaginella tamariscina dry powder Hemostasis, effect are fine.Selaginella tamariscina has beautification function.Reconciled with volume phase dry powder and egg and spread on face, face can be made bright and clean beautiful. Selaginella tamariscina is taken orally, there is strong cloudy strengthening the essence.

The extracting method of spikemoss extract：

Selaginella tamariscina will be dried to crush, after sieving, ethanol water refluxing extraction 2-3 time for being 60-80% with volumetric concentration, conjunction And ethanol extract, after filtering while hot, ethanol is distilled to recover under 0.05-0.1MPa, is 0.05-0.1MPa in vacuum, temperature Spend to dry to constant weight at 35-45 DEG C, obtain spikemoss extract.

Contain Ge Laikeyin in spikemoss extract, there is SuperPro waterpower, strengthen skin moisture retention, elasticity and smoothness, And there is anti-oxidation function and n cell activator, there is potent purification flesh bottom, remove free radical and blackhead grease soils, swash Skin Cell living and reproducibility, maintain pore clearly with accelerating wound healing and tissue repair and accelerated ageing collagen precursor Synthesis, mitigate rubefaction, resist erythema.

In one embodiment, the oligopeptides -1 in the oligopeptides and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：(0.5-1.2)：(0.2-0.7)；Preferably, the oligopeptides -1 and the palmityl tripeptides -5, institute The weight ratio for stating acetyl group pentapeptide -1 is 1：0.6：0.3.

The oligopeptide cpds can remove reduction biomolecule and facilitate the oxygen radical of skin elasticity function, and therefore prevent The only biooxidation reactions of skin；The oligopeptides can improve wrinkle of skin by increasing the synthesis of collagen in skin, by This causes the increase of elastomer in dermis of skin；The oligopeptides has the function that to suppress contraction of muscle or loosening all muscles.Especially It is that loosening all muscles effect occurs in the used facial expression muscle when people make the facial expression such as smiled or frowned In, and oligopeptide cpds can reduce the convergent force of mimetic muscle.

In one embodiment, component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, delayed The 2%-10% of the weight of the skin care compositions of aging；Preferably, component A and the B component sum has reparation again to be described Life, replenishing water and preserving moisture, anti-aging skin care compositions weight 3.6%.

In one embodiment, the weight ratio of the component A and the B component is (5-12)：1；Preferably, the A The weight ratio of component and the B component is 8：1.

In one embodiment, modification of chitosan described in the component C to be described there is reparative regeneration, moisturizing to protect The 5-20% of the weight of wet, anti-aging skin care compositions；Preferably, modification of chitosan is described described in the component C With reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions weight 11%.

In one embodiment, the surfactant is to include lecithin, saponin, alkylglycoside, anionic surface It is one or more in activating agent, cationic surfactant, nonionic surfactant, amphoteric surfactant.

The anion surfactant include sodium laurate, odium stearate, enuatrol, leukotrienes sodium, alkyl sulfate, Alkyl benzene sulphonate, such as hexyl benzene sulfonic acid, octyl benzene sulfonic acid, DBSA and analog and its salt, polyoxyalkylene It is alkyl ether sulfate, polyoxyalkylene alkenyl ether sulfate, polyoxyethylene alkyl sulfate salt, alkyl sulphosuccinates salt, poly- Oxyalkylene alkyl sulphosuccinates salt, polyoxyalkylene alkyl phenyl ether sulfate, alkane sulfonate, octyl trimethyl hydroxide Ammonium, trimethyl ammonium hydroxide, alkylsulfonate, polyoxyethylene alkylphenyl ether sulfate salt, polyoxyalkylene alkyl Acetate, alkylphosphonic, polyoxyalkylene alkyl phosphate, acyl glutamate, α-acyl group sulfonate, alkylsulfonate, Alkylallyl sulfonate, alpha-alkene sulfonate, alkylnaphthalene sulfonate, alkane sulfonate, alkyl or alkenyl sulfate, alkyl acyl Amine sulfate, alkyl or alkenyl phosphate, alkylamide phosphate, alkanoylalkyl taurate, N- acyl aminos hydrochlorate, sulphur Base succinate, alkyl ether carboxy acid salt, Amide Ether Carboxylates, alpha-sulfo fatty acid ester salt, alanine derivatives, glycine derive It is one or more in thing, arginine derivative.

The cationic surfactant includes alkyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, lauryl three Ammonio methacrylate, hexadecyltrimethylammonium chloride, tallow alkyl trimethyl ammonium chloride, behenyl base trimethyl ammonium chloride, tristearin Base trimethylammonium bromide, behenyl base trimethylammonium bromide, VARISOFT TA100, two cocoyl alkyl dimethyl ammonium chlorides, Quaternium 24, two (POE) oleyl methyl (2OE) ammonium chlorides, BZK, alkyl benzalkonium chloride, alkyl two Methyl benzalkonium chloride, benzethonium chloride, stearalkonium chloride, lanolin derivative quaternary ammonium salt, stearic acid diethyl Amino acetamide, stearic acid dimethylamino propionamide, behenamide propyl-dimethyl hydroxypropyl ammonium chloride, stearyl courage Amido formacyl methyl chloropyridine (stearoylcolaminoformylmethylpyridinium chloride), chlorine Change one or more in cetyl pyridinium, tall oil alkyl benzyl ethoxy imidazolitm chloride quinoline and benzyl ammonium salt.

The nonionic surfactant includes polyoxyalkylene ether, polyoxyalkylene alkyl, polyoxyalkylene fatty acid ester, poly- Oxyalkylene fatty acid diesters, polyoxyalkylene resins acid esters, polyoxyalkylene (hardening) castor oil, polyoxyalkylene alkyl phenol, polyoxygenated Allylic alkylation phenyl ether, polyoxyalkylene phenyl ether, polyoxyalkylene alkyl ester, polyoxyalkylene alkyl ester, Sorbitan alcohol ester Fat acid esters, polyoxyalkylene sorbitan alcohol Arrcostab, polyoxyalkylene sorbitan alcohol fatty acid ester, polyoxyalkylene sorbitol Fatty acid ester, polyoxyalkylene fatty acid glyceride, polyglycerol alkyl ether, polyglyceryl fatty acid ester, sucrose fatty ester, aliphatic acid It is alkanolamide, alkyl-glucoside, polyoxyalkylene fatty acid diphenyl ether, polypropylene glycol, diethylene glycol, polyoxyalkylene-modified Silicone, the modified silicone of the polyglyceryl silicone, the glyceryl that the are modified silicone, the sugar that are modified, the surfactant based on fluorine, poly- It is one or more in oxygen ethene/polyoxypropylene block copolymers and alkyl polyoxyethylene/polyoxypropylene block copolymers ether.

The amphoteric surfactant includes imidazoline type, amide betaine type, alkyl betaine-type, alkylamide beet Alkaline, alkyl sulfo betaines type, amide sulfo betaine type, hydroxy sulfo betaine type, carbon betaine type (carbobetainetype), phosphoric acid betaine type, aminocarboxylic acid type and amidoamino acid type amphoteric surfactant.More specifically Ground, as the example, imidazoline type amphoteric surfactant is can be mentioned that, such as, 2- undecyls-N, N, N- (carboxymethyl hydroxyethyl first Base) -2- imidazolines sodium, the imidazoline hydroxide -1- carboxylic ethyoxyl disodium salts of 2- cocoyls -2；Alkyl betaine-type both sexes table Face activating agent, such as lauryl dimethyl oxyneurine, myristyl betaine；And amide betaine type amphoteric surface Activating agent, such as coco-nut oil fatty acid amido propyl dimethylamino acetic acid glycine betaine, palm kernel fatty acid amido propyl diformazan Oxyneurine, tallow acid amido propyl dimethylamino acetic acid glycine betaine, the tallow acid amido propyl of hardening Dimethylamino acetic acid glycine betaine, lauric amide dimethylamine oxyneurine, myristic acid amido propyl dimethylamino Acetic acid glycine betaine, palmitamide dimethylamine oxyneurine, stearic amide dimethylamine oxyneurine, Oleamide dimethylamine oxyneurine；Alkyl sulfo betaines type amphoteric surfactant, such as coconut oil fat Sour dimethyl sulfopropyl betaine；Alkyl hydroxy sulfobetaine type amphoteric surfactant, such as lauryl dimethyl amine amino hydroxyl Base sulfobetaines；Phosphoric acid betaine type amphoteric surfactant, such as lauryl di glycine betaine；Amidoamino acid type Amphoteric surfactant, such as N- lauroyl-N '-ethoxy-N '-carboxymethyl sodium ethylenediamine, N- oleoyls-N '-ethoxy-N '- Carboxymethyl sodium ethylenediamine, N- cocoyls-N '-ethoxy-N '-carboxymethyl sodium ethylenediamine, N- lauroyl-N '-ethoxy-N '-carboxylic Methyl ethylenediamine potassium, N- oleoyls-N '-ethoxy-N '-carboxymethyl ethylenediamine potassium, N- lauroyl-N- ethoxys-N '-carboxymethyl second Diamines sodium, N- oleoyl-N- ethoxys-N '-carboxymethyl sodium ethylenediamine, N- cocoyl-N- ethoxys-N '-carboxymethyl sodium ethylenediamine, N- lauroyl-N- ethoxys-N ', N '-sodium of dicarboxyl methyl ethylenediamine one, N- oleoyl-N- ethoxys-N ', N '-two carboxymethyls second two The sodium of amine one, N- cocoyl-N- ethoxys-N ', N '-sodium of dicarboxyl methyl ethylenediamine one, N- lauroyl-N- ethoxys-N ', N '-two Carboxymethyl ethylenediamine disodium, N- oleoyl-N- ethoxys-N ', N '-dicarboxyl methyl ethylenediamine disodium, N- cocoyl-N- ethoxys- N ', N '-dicarboxyl methyl ethylenediamine disodium.

In one embodiment, the essence is ambergris, castoreum, Moschus, civetta, attar of rose, peppermint oil, stayed It is one or more in blue sesame oil, lavender oil, fennel oil, tea tree ethereal oil.

In one embodiment, the colouring agent is a kind of in capsanthin, chrysanthemum, flower colouring agent glycosides.

Cosmetic base is oleaginous bases, silty matrix or solvent in the present invention.

The oleaginous bases be coconut oil, castor oil, olive oil, palm oil, mink oil, snake oil, tallow, lanolin, bar It is one or more in western palm wax, spermaceti, beeswax, vaseline, atoleine, saualane, silicone oil.

The silty matrix is one or more in talcum powder, kaolin, zinc white, titanium dioxide, bentonite.

The solvent is in water, ethanol, isopropanol, butanediol, n-butanol, acetone, butanone, ethyl acetate, butyl acetate It is one or more.

In one embodiment, the modification of chitosan is with N- methylglycocyamines (CAS：It is 6020-87-7) original Material, catalytic reaction are prepared guanidine radicals chitosan, are then grafted 2,3- epoxypropyltrimethylchloride chlorides.

The preparation method of the modification of chitosan comprises the following steps：

(1) guanidine radicals chitosan：Chitosan, MES/hydrochloride buffer (2- morpholine second sulphurs are added into reactor Acid concentration 25mmol/L, pH=5), after stirring and dissolving, add coupling agent EDC (1- ethyls-(3- dimethylaminopropyls) carbon two Inferior amine salt hydrochlorate) and NHS (n-hydroxysuccinimide), stir 0.5h；N- methylglycocyamines are added, condition is stirred at room temperature Lower successive reaction 12h, a small amount of hydroxylamine hydrochloride terminating reaction is added, and pH to 9 is adjusted with standard caustic soda solution, obtain guanidine radicals shell Change glycan product, product is loaded into the bag filter that molecular cut off is 8000, distilled water is freeze-dried after dialysing one week, obtains guanidine Base chitosan；The chitosan and the MES/hydrochloride buffer, the weight ratio of the coupling agent EDC and NHS For 1：12：0.05；EDC described in the coupling agent and NHS weight ratio is 1：1.2；The chitosan and the N- first The mol ratio of base glycocyamine is 1：0.5；

(2) modification of chitosan：Guanidinated chitosan, isopropanol are added into reactor, is warming up to 75-80 DEG C, stirring 0.5h, 2, the 3- epoxypropyltrimethylchloride chloride aqueous solution is slowly added dropwise, insulation reaction 6h, is concentrated under reduced pressure and removes solvent, then Acetone is added, 50 DEG C of stirring 1h is warming up to, is cooled to room temperature and stirs 1h, filter, 60 DEG C are dried under reduced pressure 20h, obtain being modified shell Glycan；The weight ratio of the guanidine radicals chitosan and the isopropanol, acetone is 1：8：6；The 2,3- epoxies chlorine The weight ratio for changing ammonium and guanidine radicals chitosan is 0.3:1.

In terms of cosmetics, quaternary ammonium salt group is introduced in chitosan molecule, enhances its water solubility, and season is introduced in molecule Ammonium salt groups are more, and the hydratability of molecule is stronger, and moisture holding capacity is also stronger.

Chitosan quaternary ammonium salt no cytotoxicity, not haemolysis, non-sensitization, there is excellent biocompatibility and film forming, can Nutritional ingredient is fully kept, due to good film forming, chitosan film quaternary ammonium salt can form natural screen together on human epidermal Barrier, it can block or weaken ultraviolet and the infringement to skin such as germ, also good bacteriostasis antibiosis performance.Chitosan film season The characteristics of ammonium salt maximum is its outstanding hygroscopicity and moisture retention, because its structure and moisturizing mechanism hyaluronic acid are similar, quilt It is considered the favorable substitutes of hyaluronic acid.

In one embodiment, cosmetic also includes dipotassium glycyrrhizinate, double (methylol) imidazoles in the component C Ureine.

Present 90 percent application on human skin is all that expression activitiy is weak, and skin is more obscure, and water oil is uneven, dries, carefully Line, wrinkle, skin tarnish.

In the present invention dendrobium candidum extract have moistening effect is good, can desalinate microgroove, lasting moisturizing, repair it is impaired Skin quality and other effects；Aloe extract has bactericidal action, antiinflammatory action, moistens beautification function, the effect of letting out under stomach invigorating, cardiac stimulant promoting blood circulation Effect, immune and palingenesis, immune and antitumor action, detoxication, anti-aging effects, analgesia, sedation, sun-proof work With；Promote wound healing, immunological regulation, anti-oxidant, antibacterial, antiviral；Bergamot extract can purifying skin, anti-inflammatory convergence, Pore refining, help dark sore wound healing；Gotu Kola P.E can be compacted epidermis and corium coupling part, and skin can be made to become soft Soft, help promotes collagen in skin corium to be formed, and has the effect for making skin compact, and also assists in impaired organization healing and tight Real skin, promote the close connection between epidermis and corium, suppress the increase of adipocyte, prevent hydroderma, obesity occur； Fructus Sechii edulis extract also has good skin whitening, moisturizing moisturizing effect to skin, long-term use can make skin recover it is white touched with red, Water moistens full health status；Ge Laikeyin in spikemoss extract, there is SuperPro waterpower, enhancing skin moisture retention, elasticity With smoothness, and there is anti-oxidation function and n cell activator, there is potent purification flesh bottom, remove free radical and blackhead oil Fat dirt, activate Skin Cell and reproducibility, maintain pore clearly with accelerating wound healing and tissue repair and accelerated ageing glue The synthesis of former amyloid protein precursor, mitigate rubefaction, resist erythema.

Guanidine radicals is that a kind of alkalescence is very strong and the organic base of positively charged, introduces guanidine radicals in modification of chitosan in the present invention, enters one Step improves the antibiotic property and water solubility of chitosan, and also has certain flocculation, extends nutrition in skin care compositions The action time of composition, Glycerin and Cucumber Extract, while acceptable lasting moisturizing, water lock；By being grafted 2,3- epoxies third Base trimethyl ammonium chloride, further enhance its water-soluble, hydratability, moisture holding capacity and bacteriostasis antibiosis performance of molecule.

There is skin care compositions of the present invention nutrition to moisten, Cucumber Extract, replenishing water and preserving moisture, reparative regeneration, desalination microgroove, anti-anaphylaxis Antiallergic, skin metabolic balance is maintained, delay cell senescence, desalination colouring agent is calm and dark yellow, makes skin fine and smooth, pale, bright and clean And high resilience, acceptable lasting moisturizing, water lock, lift skin.

The present invention is specifically described below by embodiment.It is necessarily pointed out that following examples are only used In the invention will be further described, it is impossible to be interpreted as limiting the scope of the invention, professional and technical personnel in the field Some the nonessential modifications and adaptations made according to the content of the invention described above, still fall within protection scope of the present invention.

In addition, if without other explanations, it is raw materials used be all it is commercially available, be purchased from traditional Chinese medicines chemical reagent.

Embodiment 1

The cosmetics are emulsion, are calculated by weight, described in the cosmetics have reparative regeneration, replenishing water and preserving moisture, The skin care compositions of anti-aging includes：

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

It is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions preparation method, including following step Suddenly：

Embodiment 2

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.2：7：0.5：1：1.1：0.3；The B component For oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group five The weight ratio of peptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, delayed The 3.6% of the weight of the skin care compositions of aging；The weight ratio of the component A and the B component is 8：1；The component C is change Cosmetic auxiliary material and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, glycyrrhizic acid in the component C Dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C to be described there is reparative regeneration, moisturizing to protect The 11% of the weight of wet, anti-aging skin care compositions；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

It is described to gather with reparative regeneration, replenishing water and preserving moisture, the preparation method of skin care compositions of anti-aging, the modified shell The preparation method of sugar is the same as embodiment 1.

Embodiment 3

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 1：7：0.5：3：1.1：1；The B component is widow Peptide -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group pentapeptide -1 Weight ratio be 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture, anti-aging to be described Skin care compositions weight 3.6%；The weight ratio of the component A and the B component is 8：1；The component C is cosmetics Auxiliary material and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, glycyrrhizic acid two in the component C Potassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C for it is described have reparative regeneration, replenishing water and preserving moisture, The 11% of the weight of the skin care compositions of anti-aging；The surfactant is odium stearate, and the essence is attar of rose；Institute It is ethanol, butanediol, water to state cosmetic base in component C；

Embodiment 4

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.5：0.7；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 5

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：1.2：0.2；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 6

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 2.0% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 9：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 7

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 6.4% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 8

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 5：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 9

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 11：1；The component C For cosmetic and cosmetic base, in the component C cosmetic be modification of chitosan, it is surfactant, essence, sweet Oxalic acid dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, benefit to be described Water moisturizing, anti-aging skin care compositions weight 11%；The surfactant is odium stearate, and the essence is rose Rare oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 10

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 5%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Embodiment 11

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is modification of chitosan, surfactant, essence, radix glycyrrhizae in the component C Sour dipotassium, Bis(hydroxymethyl)imidazolidinyl urea；Modification of chitosan described in the component C has reparative regeneration, moisturizing to be described Moisturizing, anti-aging skin care compositions weight 20%；The surfactant is odium stearate, and the essence is rose Oil；Cosmetic base is ethanol, butanediol, water in the component C；

Comparative example 1

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group The weight ratio of pentapeptide -1 is 1：0.6：0.3；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture for described in, prolonged The 3.6% of the weight of the skin care compositions of slow aging；The weight ratio of the component A and the B component is 8：1；The component C is Cosmetic and cosmetic base, cosmetic is chitosan, surfactant, essence, glycyrrhizic acid two in the component C Potassium, Bis(hydroxymethyl)imidazolidinyl urea；Chitosan described in the component C has reparative regeneration, replenishing water and preserving moisture for described in, delayed The 11% of the weight of the skin care compositions of aging；The surfactant is odium stearate, and the essence is attar of rose；The C Cosmetic base is ethanol, butanediol, water in component；

Comparative example 2

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A be dendrobium candidum extract, aloe extract, bergamot extract, the dendrobium candidum extract with it is described Aloe extract, the weight ratio of the bergamot extract are 0.6：7：0.5；The B component be oligopeptides -1, palmityl tripeptides - 5th, the weight ratio of acetyl group pentapeptide -1, the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group pentapeptide -1 is 1：0.6： 0.3；Component A and the B component sum for it is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions weight The 3.6% of amount；The weight ratio of the component A and the B component is 8：1；The component C is cosmetic and cosmetics base Matter, cosmetic is modification of chitosan, surfactant, essence, dipotassium glycyrrhizinate, double (methylol) miaows in the component C Oxazolidinyl urea；Modification of chitosan described in the component C is the skin care with reparative regeneration, replenishing water and preserving moisture, anti-aging The 11% of the weight of composition；The surfactant is odium stearate, and the essence is attar of rose；Made up in the component C Product matrix is ethanol, butanediol, water；

Comparative example 3

It is described that there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, including component A, B component and C groups Point；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, chocho extraction Thing, spikemoss extract, the dendrobium candidum extract and the aloe extract, the bergamot extract, the centella Extract, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7；The B groups It is divided into oligopeptides -1；Component A and the B component sum has reparative regeneration, replenishing water and preserving moisture, the skincare composition of anti-aging to be described The 3.6% of the weight of thing；The weight ratio of the component A and the B component is 8：1；The component C is cosmetic and cosmetic Product matrix, cosmetic is modification of chitosan, surfactant, essence, dipotassium glycyrrhizinate, double (hydroxyl first in the component C Base) imidazolidinyl urea；Modification of chitosan described in the component C is described with reparative regeneration, replenishing water and preserving moisture, anti-aging The 11% of the weight of skin care compositions；The surfactant is odium stearate, and the essence is attar of rose；In the component C Cosmetic base is ethanol, butanediol, water；

It is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions preparation method, the modified shell gathers The preparation method of sugar is the same as embodiment 1.

Performance test：

1st, reparative regeneration effect clinical observation on the therapeutic effect

Dark and gloomy matt, unsystematic disease the 15-35 of choosing face patient 160, carries out routine examination before on probation：The heart Electrograph, blood urine are just conventional, hepatic and renal function is showed no exception.160 people are randomly divided into two groups.Tested group 140；Control group 20, Every group of M-F is similar.Tested group：Every night facial massage is uniformly applied to after face cleaning extremely using the emulsifiable paste provided in embodiment Naturally absorb.Control group：A little dimension E Weifu pastes are smeared after morning and evening clean skin in face, and gently massage 1-3 minutes, continuous use 30 days.

Curative effect determinate standard：

Cure：With rear dark and gloomy matt obvious desalination.

It is effective：Desalinated with rear dark and gloomy tarnish.

It is invalid：With rear dark and gloomy tarnish without mitigation.

2nd, the research of moisture-keeping function

6 pieces of glass plates for posting 3M adhesive plasters (7.5cm × 7.5cm) are taken, its quality is referred to as M respectively₀, wherein 3 pieces are blank Control, 3 pieces are sampling test.

200 μ L samples 1 and sample 2 are taken respectively, are added dropwise on the glass plate for posting 3M adhesive plasters, its quality is referred to as M₁It is (accurate To 0.0001g), sample is even, glass plate is put into the drier (being placed with ammonium sulfate saturated solution) of constant humidity, by remaining 3 pieces of blank control glass plates are put into the drier of constant humidity together.After placing 8h, glass plate is taken out, weighs the glass plate Quality is M₂, calculate as follows, determine its moisturizing rate.

Moisturizing rate=[(M₂-M₀)/(M₁-M₀)] × 100%

3rd, antibacterial anti-inflammatory Effect study.

Take 2 kinds of bacterial indicators of test strain MRSE and propionibacterium acnes.By cultivate 24h bacterial indicator and The instruction saccharomycete of culture 5 days is configured to 106 cells/mL bacteria suspensions with 50mmol/LPBS.

Sample is inoculated with the culture medium flat plate of different tests bacterial strain respectively with test sample, and propionibacterium acnes is placed in anaerobism training Support in case and cultivated 3-5 days in 37 DEG C, result is observed after 37 DEG C of culture 24h of MRSE.Sky is done instead of sample with sterilized water White control.Clump count is recorded, bacteriostasis rate is calculated as follows.

X=[(A-B)/A] × 100%

In formula, X is bacteriostasis rate, and A is control sample average colony number, and B represents test specimen average colony number.4th, cosmetics Trial effect：After 10 experimenters use 15 days, the length of wrinkle and wrinkle, depth and quantity situation around eyes are observed.

The performance test results of table 1

It is from the above-mentioned data as can be seen that provided by the invention a kind of with reparative regeneration, replenishing water and preserving moisture, anti-aging Skin care compositions, there is potent purification flesh bottom, nutrition is moistened, and Cucumber Extract, activates Skin Cell and reproducibility, maintains pore clear Refreshing and accelerating wound healing and tissue repair, desalinate microgroove, the effect of replenishing water and preserving moisture and anti-anaphylaxis antiallergic.

Foregoing example is merely illustrative, for explaining some features of the method for the invention.Appended right will Ask and be intended to require the scope as wide as possible being contemplated that, and embodiments as presented herein is only according to all possible implementation The explanation of the embodiment of the selection of the combination of example.Therefore, the purpose of applicant is that appended claim is not illustrated this hair The selectional restriction of the example of bright feature.Some number ranges used also include sub- model within the claims Enclose, the change in these scopes should be also construed to by appended claim covering in the conceived case.

Claims

1. a kind of have reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging, it is characterised in that it includes component A, B Component and component C；The component A is dendrobium candidum extract, aloe extract, bergamot extract, Gotu Kola P.E, Buddhist Hand melon extract, spikemoss extract；The B component is oligopeptides；Wherein described oligopeptides is selected from oligopeptides -1, oligopeptides -2, oligopeptides -3, widow Peptide -4, oligopeptides -5, oligopeptides -6, oligopeptides -10, Matrixyl -3, palmityl tripeptides -1, palmityl tripeptides -5, palmityl tetrapeptide - 3rd, nutmeg pentapeptide -11, acetyl group tetrapeptide -5, acetyl group pentapeptide -1, Argireline, one kind in acetyl group dipeptides -1 or It is a variety of；The component C is cosmetic and cosmetic base.

2. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 1, it is characterised in that Dendrobium candidum extract described in the component A extracts with the aloe extract, the bergamot extract, the centella Thing, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are (0.2-1)：(3-8)：(0.3-0.7)：(1-3)： (0.5-2)：(0.3-1).

3. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 2, it is characterised in that Dendrobium candidum extract described in the component A extracts with the aloe extract, the bergamot extract, the centella Thing, the Fructus Sechii edulis extract, the weight ratio of the spikemoss extract are 0.6：7：0.5：1.2：1.1：0.7.

4. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 1, it is characterised in that Oligopeptides described in the B component is oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1.

5. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 4, it is characterised in that The weight ratio of the oligopeptides -1 and the palmityl tripeptides -5, the acetyl group pentapeptide -1 in the oligopeptides is 1：(0.5- 1.2)：(0.2-0.7).

6. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 1, it is characterised in that Component A and the B component sum for it is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions weight 2%-10%.

7. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 1, it is characterised in that The weight ratio of the component A and the B component is (5-12)：1.

8. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim 1, it is characterised in that Cosmetic includes the one or more in modification of chitosan, surfactant, essence, colouring agent in the component C.

9. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to claim any one of 1-8, its Be characterised by, it is described with reparative regeneration, replenishing water and preserving moisture, anti-aging skin care compositions be applied to facial mask, eye cream, face cream, Essence, mildy wash, stoste, toner, emulsion, emulsifiable paste, hydrosol, sun screen or BB frosts.

10. there is reparative regeneration, replenishing water and preserving moisture, the skin care compositions of anti-aging according to the claim any one of 1-8 Preparation method, it is characterised in that comprise the following steps：

(2) component A dendrobium candidum extract, aloe extract, bergamot extract, centella is added into step (1) to extract Thing, Fructus Sechii edulis extract, spikemoss extract, 10-15min is stirred, is well mixed material；

(3) B component oligopeptides -1, palmityl tripeptides -5, acetyl group pentapeptide -1 are added into step (2), stirs 10-15min, mistake Filter, discharge, stand；Detect qualified rear packaging, storage.