CN107567334A - 驱蠕虫组合及其使用方法 - Google Patents

驱蠕虫组合及其使用方法 Download PDF

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Publication number
CN107567334A
CN107567334A CN201680025471.5A CN201680025471A CN107567334A CN 107567334 A CN107567334 A CN 107567334A CN 201680025471 A CN201680025471 A CN 201680025471A CN 107567334 A CN107567334 A CN 107567334A
Authority
CN
China
Prior art keywords
spp
macrolide
mammal
cyclic depsipeptide
dirofilaria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680025471.5A
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English (en)
Chinese (zh)
Inventor
B·波德森
L·哈姆兰德
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Inc filed Critical Merial Inc
Publication of CN107567334A publication Critical patent/CN107567334A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201680025471.5A 2015-04-02 2016-04-01 驱蠕虫组合及其使用方法 Pending CN107567334A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562142304P 2015-04-02 2015-04-02
US62/142,304 2015-04-02
PCT/US2016/025714 WO2016161369A1 (en) 2015-04-02 2016-04-01 Anthelmintic combinations and methods of use thereof

Publications (1)

Publication Number Publication Date
CN107567334A true CN107567334A (zh) 2018-01-09

Family

ID=57006415

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680025471.5A Pending CN107567334A (zh) 2015-04-02 2016-04-01 驱蠕虫组合及其使用方法

Country Status (18)

Country Link
US (1) US10993988B2 (https=)
EP (1) EP3277303B1 (https=)
JP (1) JP6899330B2 (https=)
KR (1) KR20170132330A (https=)
CN (1) CN107567334A (https=)
AU (1) AU2016244022A1 (https=)
BR (1) BR112017020975A2 (https=)
CA (1) CA2981489A1 (https=)
CL (1) CL2017002474A1 (https=)
CO (1) CO2017011284A2 (https=)
ES (1) ES2851345T3 (https=)
IL (1) IL254783B (https=)
MX (1) MX381319B (https=)
MY (1) MY187835A (https=)
PH (1) PH12017501806A1 (https=)
RU (1) RU2717545C2 (https=)
SG (1) SG11201708008TA (https=)
WO (1) WO2016161369A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113194937A (zh) * 2018-10-04 2021-07-30 礼蓝动物健康股份公司 蠕虫治疗的增强

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3044038A1 (en) * 2016-11-16 2018-05-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
EP3579696B1 (en) * 2017-02-08 2023-06-28 Boehringer Ingelheim Animal Health USA Inc. In vivo model for parasitic worm infection and methods for evaluating antiparasitic compounds, including compounds active against canine heartworm
CN111386112A (zh) 2017-11-23 2020-07-07 法国诗华大药厂 用于治疗寄生虫感染的含有莫昔克丁的组合物
AU2018374849B2 (en) * 2017-11-29 2021-02-18 Zoetis Services Llc Endoparasitic depsipeptides
CN116744917A (zh) 2020-09-04 2023-09-12 礼蓝美国公司 适口调配物
GB202100635D0 (en) * 2021-01-18 2021-03-03 Liverpool School Tropical Medicine Compounds and methods for treating or preventing dirofilaria infection in a mammal
UY39995A (es) 2021-11-01 2023-05-15 Boehringer Ingelheim Vetmedica GmbH Compuestos de pirrolopiridazina como antihelmínticos

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191489A (zh) * 1995-06-02 1998-08-26 拜尔公司 杀内寄生虫组合物
CN102215824A (zh) * 2008-05-07 2011-10-12 拜尔动物保健有限责任公司 具有延迟释放的固体药物制剂

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US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US20030129680A1 (en) 2001-10-31 2003-07-10 O'connor Thomas Patrick Multi-analyte assay device
US20070042354A1 (en) 2005-08-19 2007-02-22 Engelhard Eric K Detecting pathogens in companion animals
ES2367332T3 (es) * 2007-02-21 2011-11-02 Pfizer Limited Agentes antiparasitarios de benzofurano.
JP4734656B2 (ja) * 2007-03-30 2011-07-27 国立大学法人群馬大学 Ｐｆ１０２２類の製造法
US8809268B2 (en) 2008-10-29 2014-08-19 The Regents Of The University Of California Combination therapy to combat helminth resistance
BE1019407A5 (nl) 2009-11-06 2012-07-03 Momentum Animal Cure Bvba Middel voor het uitdrijven van parasieten bij mensen, dieren en vogels.
WO2011095581A1 (en) 2010-02-05 2011-08-11 Intervet International B.V. S piroindoline compounds for use as anthelminthi cs
WO2011115840A2 (en) 2010-03-14 2011-09-22 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
RU2452180C2 (ru) * 2010-08-31 2012-06-10 Общество с ограниченной ответственностью "Научно-внедренческое предприятие "Астрафарм" Комплексная антипаразитарная композиция
AU2010101389C4 (en) 2010-12-08 2017-03-02 Jurox Pty Ltd Anthelmintic formulation
AU2010249226C1 (en) 2010-12-08 2017-04-13 Zoetis Services Llc Anthelmintic formulation
WO2013017678A1 (en) 2011-08-04 2013-02-07 Intervet International B.V. Novel spiroindoline compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1191489A (zh) * 1995-06-02 1998-08-26 拜尔公司 杀内寄生虫组合物
CN102215824A (zh) * 2008-05-07 2011-10-12 拜尔动物保健有限责任公司 具有延迟释放的固体药物制剂

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KRUEDEWAGEN ET AL: "Concomitant Simultaneous and Consecutive Treatment of Imidacloprid/Moxidectin Spot-on with Emodepside/Praziquantel Tablets in Adult Dogs", 《INTERNATIONAL JOURNAL OF APPLIED RESEARCH IN VETERINARY MEDICINE 》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113194937A (zh) * 2018-10-04 2021-07-30 礼蓝动物健康股份公司 蠕虫治疗的增强

Also Published As

Publication number Publication date
MX381319B (es) 2025-03-12
BR112017020975A2 (pt) 2018-07-10
KR20170132330A (ko) 2017-12-01
IL254783A0 (en) 2017-12-31
CO2017011284A2 (es) 2018-01-31
RU2017138118A3 (https=) 2019-07-24
US20170020955A1 (en) 2017-01-26
MX2017012510A (es) 2018-01-30
JP2018510195A (ja) 2018-04-12
AU2016244022A1 (en) 2017-10-26
RU2017138118A (ru) 2019-05-06
EP3277303B1 (en) 2020-12-02
MY187835A (en) 2021-10-26
JP6899330B2 (ja) 2021-07-07
US10993988B2 (en) 2021-05-04
ES2851345T3 (es) 2021-09-06
WO2016161369A1 (en) 2016-10-06
EP3277303A1 (en) 2018-02-07
CL2017002474A1 (es) 2018-03-23
IL254783B (en) 2020-11-30
PH12017501806A1 (en) 2018-04-11
SG11201708008TA (en) 2017-10-30
CA2981489A1 (en) 2016-10-06
RU2717545C2 (ru) 2020-03-24

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Effective date of registration: 20190715

Address after: Georgia

Applicant after: Bollinger Ingham Animal Health USA

Address before: Georgia

Applicant before: Cimmeria limited-liability company

TA01 Transfer of patent application right
RJ01 Rejection of invention patent application after publication

Application publication date: 20180109

RJ01 Rejection of invention patent application after publication