CL2017002474A1 - Combinaciones antihelmínticas y los métodos de usos de las mismas - Google Patents

Combinaciones antihelmínticas y los métodos de usos de las mismas

Info

Publication number
CL2017002474A1
CL2017002474A1 CL2017002474A CL2017002474A CL2017002474A1 CL 2017002474 A1 CL2017002474 A1 CL 2017002474A1 CL 2017002474 A CL2017002474 A CL 2017002474A CL 2017002474 A CL2017002474 A CL 2017002474A CL 2017002474 A1 CL2017002474 A1 CL 2017002474A1
Authority
CL
Chile
Prior art keywords
methods
prophylaxis
treatment
macrocyclic lactone
anthelmintic
Prior art date
Application number
CL2017002474A
Other languages
English (en)
Inventor
Brenda Bondesen
Lance Hammerland (Fallecido)
Original Assignee
Merial Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=57006415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2017002474(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial Inc filed Critical Merial Inc
Publication of CL2017002474A1 publication Critical patent/CL2017002474A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<p>La presente invención se relaciona con una composición veterinaria comprendiendo una cantidad efectiva de al menos un depsipéptido cíclico y al menos una lactona macrocíclica; y un vehículo farmacéuticamente aceptable, para el tratamiento o profilaxis de la infección parasítica en un mamífero donde el parásito muestra resistencia a tratamiento o profilaxis con la lactona macrocíclica sola.</p>
CL2017002474A 2015-04-02 2017-10-02 Combinaciones antihelmínticas y los métodos de usos de las mismas CL2017002474A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562142304P 2015-04-02 2015-04-02

Publications (1)

Publication Number Publication Date
CL2017002474A1 true CL2017002474A1 (es) 2018-03-23

Family

ID=57006415

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2017002474A CL2017002474A1 (es) 2015-04-02 2017-10-02 Combinaciones antihelmínticas y los métodos de usos de las mismas

Country Status (18)

Country Link
US (1) US10993988B2 (es)
EP (1) EP3277303B1 (es)
JP (1) JP6899330B2 (es)
KR (1) KR20170132330A (es)
CN (1) CN107567334A (es)
AU (1) AU2016244022A1 (es)
BR (1) BR112017020975A2 (es)
CA (1) CA2981489A1 (es)
CL (1) CL2017002474A1 (es)
CO (1) CO2017011284A2 (es)
ES (1) ES2851345T3 (es)
IL (1) IL254783B (es)
MX (1) MX2017012510A (es)
MY (1) MY187835A (es)
PH (1) PH12017501806A1 (es)
RU (1) RU2717545C2 (es)
SG (1) SG11201708008TA (es)
WO (1) WO2016161369A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11382949B2 (en) * 2016-11-16 2022-07-12 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
HRP20230870T1 (hr) * 2017-02-08 2023-11-10 Boehringer Ingelheim Animal Health USA Inc. Model in vivo za infekciju parazitnim crvima i postupak ocjenjivanja antiparazitnih spojeva, uključujući spojeve koji djeluju protiv pseće dirofilarioze
AU2018372008B2 (en) 2017-11-23 2024-03-28 Ceva Sante Animale Composition containing moxidectin for treating parasites infestations
UA125155C2 (uk) * 2017-11-29 2022-01-19 Зоетіс Сервісіс Ллк Анти-ендопаразитарні депсипептиди
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
CA3236894A1 (en) 2021-11-01 2023-05-04 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
DE19520275A1 (de) * 1995-06-02 1996-12-05 Bayer Ag Endoparasitizide Mittel
US20030129680A1 (en) 2001-10-31 2003-07-10 O'connor Thomas Patrick Multi-analyte assay device
US20070042354A1 (en) 2005-08-19 2007-02-22 Engelhard Eric K Detecting pathogens in companion animals
WO2008102232A1 (en) * 2007-02-21 2008-08-28 Pfizer Limited Benzofuran antiparasitic agents
JP4734656B2 (ja) * 2007-03-30 2011-07-27 国立大学法人群馬大学 Ｐｆ１０２２類の製造法
DE102008022520A1 (de) 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
WO2010053517A2 (en) 2008-10-29 2010-05-14 Aroian Raffi V Combination therapy to combat helminth resistance
BE1019407A5 (nl) 2009-11-06 2012-07-03 Momentum Animal Cure Bvba Middel voor het uitdrijven van parasieten bij mensen, dieren en vogels.
CN102741252A (zh) 2010-02-05 2012-10-17 英特维特国际股份有限公司 用作驱虫剂的螺吲哚啉化合物
US9758840B2 (en) 2010-03-14 2017-09-12 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
RU2452180C2 (ru) 2010-08-31 2012-06-10 Общество с ограниченной ответственностью "Научно-внедренческое предприятие "Астрафарм" Комплексная антипаразитарная композиция
AU2010249226C1 (en) 2010-12-08 2017-04-13 Zoetis Services Llc Anthelmintic formulation
AU2010101389C4 (en) 2010-12-08 2017-03-02 Jurox Pty Ltd Anthelmintic formulation
EP2739626B1 (en) 2011-08-04 2016-05-04 Intervet International B.V. Novel spiroindoline compounds

Also Published As

Publication number Publication date
CO2017011284A2 (es) 2018-01-31
RU2017138118A (ru) 2019-05-06
CA2981489A1 (en) 2016-10-06
KR20170132330A (ko) 2017-12-01
AU2016244022A1 (en) 2017-10-26
EP3277303B1 (en) 2020-12-02
IL254783B (en) 2020-11-30
JP2018510195A (ja) 2018-04-12
MX2017012510A (es) 2018-01-30
IL254783A0 (en) 2017-12-31
SG11201708008TA (en) 2017-10-30
US10993988B2 (en) 2021-05-04
CN107567334A (zh) 2018-01-09
US20170020955A1 (en) 2017-01-26
PH12017501806A1 (en) 2018-04-11
WO2016161369A1 (en) 2016-10-06
EP3277303A1 (en) 2018-02-07
ES2851345T3 (es) 2021-09-06
JP6899330B2 (ja) 2021-07-07
MY187835A (en) 2021-10-26
RU2717545C2 (ru) 2020-03-24
RU2017138118A3 (es) 2019-07-24
BR112017020975A2 (pt) 2018-07-10

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