CN107460156B - 无血清全悬浮mdck细胞株及其在生产流感病毒中的应用 - Google Patents
无血清全悬浮mdck细胞株及其在生产流感病毒中的应用 Download PDFInfo
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CN201610389624.6A CN107460156B (zh) | 2016-06-03 | 2016-06-03 | 无血清全悬浮mdck细胞株及其在生产流感病毒中的应用 |
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Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108130315B (zh) * | 2017-12-20 | 2021-08-13 | 哈药集团生物疫苗有限公司 | H3n2亚型猪流感病毒细胞适应株及其制备的灭活疫苗和应用 |
CN108396006A (zh) * | 2018-01-25 | 2018-08-14 | 武汉珈创生物技术股份有限公司 | 一种bhk-21细胞株及其培养方法和用途 |
IL298567B2 (en) * | 2018-11-08 | 2023-10-01 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Substrate contact independent cells and their uses |
CN110237246B (zh) * | 2019-07-25 | 2022-11-15 | 北京鼎持生物技术有限公司 | 一种全悬浮细胞培养禽流感(h9)灭活疫苗的方法 |
CN111117944B (zh) * | 2019-11-22 | 2022-05-24 | 中农威特生物科技股份有限公司 | 一种用于规模化悬浮培养的抗凋亡mdck宿主细胞株及其建立方法 |
CN111440762B (zh) * | 2020-04-14 | 2020-12-04 | 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) | 一种全悬浮mdck细胞和利用全悬浮mdck细胞培养猪流感病毒的方法 |
CN114606197A (zh) * | 2022-02-25 | 2022-06-10 | 华中农业大学 | 适合腺病毒载体增殖的MDCK-KOslc35b2细胞系及其应用 |
CN114438019B (zh) * | 2022-03-11 | 2023-01-03 | 上海荣盛生物药业股份有限公司 | 一种mdck细胞系的驯化方法 |
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WO2004110484A1 (fr) * | 2003-06-18 | 2004-12-23 | Gosudarstvenny Nauchny Tsentr Virusologii I Biotekhnologii 'vektor' | Procede de production d'un vaccin vivant de culture contre le virus de la grippe |
WO2011134163A1 (zh) * | 2010-04-29 | 2011-11-03 | 扬州优邦生物制药有限公司 | 一种h9n2亚型禽流感灭活疫苗的制备方法及产品 |
CN102816732A (zh) * | 2012-06-28 | 2012-12-12 | 北京健翔和牧生物科技有限公司 | 适应全悬浮无血清培养的mdck细胞系及其在培养流感病毒、生产流感病毒疫苗中的应用 |
CN103154238A (zh) * | 2010-09-06 | 2013-06-12 | Sk化学公司 | 适应于无血清培养和悬浮培养的mdck来源的细胞系与利用该细胞制备疫苗病毒的方法 |
CN104726392A (zh) * | 2013-12-18 | 2015-06-24 | 普莱柯生物工程股份有限公司 | 一种制备无血清培养的悬浮哺乳动物细胞系的方法、及其制备的细胞系和应用 |
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- 2016-06-03 CN CN201610389624.6A patent/CN107460156B/zh active Active
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WO2004110484A1 (fr) * | 2003-06-18 | 2004-12-23 | Gosudarstvenny Nauchny Tsentr Virusologii I Biotekhnologii 'vektor' | Procede de production d'un vaccin vivant de culture contre le virus de la grippe |
WO2011134163A1 (zh) * | 2010-04-29 | 2011-11-03 | 扬州优邦生物制药有限公司 | 一种h9n2亚型禽流感灭活疫苗的制备方法及产品 |
CN103154238A (zh) * | 2010-09-06 | 2013-06-12 | Sk化学公司 | 适应于无血清培养和悬浮培养的mdck来源的细胞系与利用该细胞制备疫苗病毒的方法 |
CN102816732A (zh) * | 2012-06-28 | 2012-12-12 | 北京健翔和牧生物科技有限公司 | 适应全悬浮无血清培养的mdck细胞系及其在培养流感病毒、生产流感病毒疫苗中的应用 |
CN104726392A (zh) * | 2013-12-18 | 2015-06-24 | 普莱柯生物工程股份有限公司 | 一种制备无血清培养的悬浮哺乳动物细胞系的方法、及其制备的细胞系和应用 |
Non-Patent Citations (1)
Title |
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用于流感疫苗生产的MDCK悬浮细胞流加培养工艺的开发;贾涵婧;《中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑》;20151215(第12期);第15页第1-3段,图3.1,第19-20页第3.3.3节,第27页第4.2部分,第29页第1-2段 * |
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