CN107232594A - A kind of complex health care product of strengthen immunity - Google Patents
A kind of complex health care product of strengthen immunity Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides a kind of complex health care product of strengthen immunity.A kind of complex health care product of strengthen immunity, is mainly made up of following component：By weight, 100 200 parts of lycopene oleoresin, 200 300 parts of pumpkin seed oil, 30 70 parts of ganoderma lucidum spore oil, 5 20 parts of vitamin E.The complex health care product of the present invention utilizes the compatibility relationship of science; pass through the coordinated of various materials; start with from multiple dimensions; blood circulation system, the undesirable element in immune system and the cancer activity factor of human body are eliminated comprehensively; blood circulation system and the physiological function of immune system are lifted, and is at good operating condition, the immunity of human body is drastically increased; male prostate, prevention and suppression tumour cell generation are protected simultaneously；And it is natural to draw materials, without any toxicity and side effects.
Description
Technical field
The present invention relates to health product technology field, more particularly, to a kind of complex health care product of strengthen immunity.
Background technology
Immunity is the defense mechanism of human body itself, is that human bioequivalence and any foreign matter for eliminating external intrusion are (viral, thin
Bacterium etc.), processing aging, damage, death, the own cells of denaturation, and identification and processing vivo mutations cell and virus are infected
The ability of cell is human bioequivalence and excludes the physiological reaction of " dissident ".Most of disease of the mankind all with it is immune relevant, it is common
Autoimmune disease also have endocrine autoimmune disease, systemic rheumatism, haematogenic immunity disease, cutaneous immunisation disease
Disease, digestive system immunity disease and kidney immunity disease, such as allow the leukaemia of people's " hearing sickly complexion to become ", is exactly that blood is exempted from
One kind in epidemic disease.
In addition, research shows that cancer and immunity have certain indirect relation.Body immunity can effectively remove one when high
A little necrosis, malignant cell, removing toxins in human body, the function with " removing rubbish ", so for, the high people of immunity, energy
Part of cancerous cell is killed in the resistance of oneself effective, controls the further development of cancer cell.
Modern medical science also found, the factor of immune to be one have with aging substantial connection, and immunocyte decline is to decline
One of old most important reason.Some special cells of body immune system can by the bacterium in invasion body, virus and in vivo
The cell of aging death, the cell being mutated and the material for causing allergy, are wholly swallowed and are eliminated, from internal
The stabilization of environment, keeps body health.But body's immunity began to decline at 30 years old or so, this change is quietly, delayed
Slowly, it is continued for.
It can be seen that, either for which aspect, improve autoimmunity all most important to health.Grass in natural drug
Medicine is the material that the mankind apply earliest, and China's traditional medicine increasingly payes attention to improving the research and application of immunity medicine.State
Interior scholar proves that the extract in Fuzheng herbs such as the Radix Astragali, ginseng, wilsonii, umbellate pore furgus, white fungus and rainbow conk has obvious in recent years
Immunological enhancement, macrophage phagocytic function can be promoted, enhancing T cell vigor and antibody are formed, be the anti-of significant
Old medicine.However, there are 12807 kinds of natural Chinese medicinal herb resources in China, and it is conventional, different Chinese herbal medicine to machine wherein there was only 10%
The influence emphasis of body immune system is also different, it is still necessary to which further investigation is utilized.Therefore, in order to improve the immune of people
The health products that power is preferably used to strengthen immunologic function there is provided new, effect are that this area technology urgently to be resolved hurrily is asked
Topic.
In view of this, it is special to propose the present invention.
The content of the invention
It is an object of the invention to provide a kind of complex health care product of strengthen immunity, described complex health care product utilizes section
Compatibility relationship, the effect with more significant immunity enhancing effect, effectively enhancing prevention and suppression tumour generation, especially
Prevention and treatment to prostate cancer, and it is natural to draw materials, without any toxicity and side effects.
In order to realize the above object the invention provides following technical scheme：
A kind of complex health care product of strengthen immunity, is mainly made up of following component：By weight,
Wherein, the lycopene in lycopene oleoresin is a Carotenoids, with preventing and suppress cancer cell
Effect.Its physiologically active is realized from oxidative damage by protecting body cell.Lycopene adjusts blood fat, prevents heart and brain blood
Pipe disease.Lycopene oleoresin can make cytothesis, and anti-aging improves energy and immunity.
Pumpkin seed oil contains abundant unrighted acid, a variety of lifes such as phytosterol, amino acid, vitamin, mineral matter
Active substances.Wherein prostate can be eliminated containing the active bio catalyzer contact agent composition that can be described as male hormones to swell initial stage
It is swollen, there is good treatment and prevention effect to urinary system and hyperplasia of prostate and cholesterol and blood glucose can be reduced, to heart and brain
Blood vessel and diabetes have prevention and health-care effect.
The triterpenes ganoderic acid that ganoderma lucidum spore oil contains has strong pharmacological activity, has protect liver, removing toxic substances, kills cancer cell
And pain-relieving functions.Unrighted acid that ganoderma lucidum spore oil contains can pre- preventing thrombosis and artery sclerosis, reduce malignant cholesterol, net
Change blood and eliminate free radical.The organic germanium that ganoderma lucidum spore oil contains has decompression, diuresis, analgesic effect, induces and promotes huge
The phagocytosis of phagocyte.Ganoderma lucidum spore oil suppresses the propagation of tumour cell by activated NK, and can be with bidirectional modulation
The immune system of human body.
Vitamin E is that life continues one of required nutrient.It can promote sex hormone to secrete, and improve fecundity, protect
T lymphocytes, protection red blood cell, Green Tea Extract oxidation are protected, the lipid peroxidation reaction in ocular lens body can be suppressed, make peripheral blood
Enlargement of pipe, improves blood circulation.
The present invention four kinds of compositions from more than, the proportioning composition complex health care product through science, can not only reach and be protected than existing
The medicinal material or auxiliary of any toxic side effect is not introduced in the strong more significant strengthen immunity effect of product, and the formula of the present invention
Material, therefore be used for a long time safer.
Specifically, in the present invention, lycopene oleoresin has superpower anti-oxidant and promotes cytothesis to act on, pumpkin
Oil has good reparation and protective effect to urinary system, cardiac-cerebral vascular, hematological system, ganoderma lucidum spore oil to immunocyte and
Liver system has good growth promotion or repairing effect, and above three synergy is re-introduced into free radical and eliminates very competent
Vitamin E, final General Promotion human physiological functions are to increase immunity.As can be seen here, the health products group that the present invention is provided
In compound, the emphasis of each component is different, but by the coordinated of various materials, starts with from multiple dimensions, disappear comprehensively
Except the undesirable element and cancer activity factor in the blood circulation system of human body, immune system, lifting blood circulation system with
And the physiological function of immune system, and good operating condition is at, and the immunity of human body is drastically increased, can be effective
Enhancing prevention and the effect for suppressing tumour generation, the especially prevention and treatment to prostate cancer.
Formula can also further optimize above, to obtain more preferable immunity enhancing effect, and for example formula is：By weight
Meter,
Oily composition has a major impact to the health-care effect of formula in all formulas described above, in order to improve health care effect
The oil of fruit preferably following quality：
Preferably, the lycopene oleoresin is through ultramicro grinding, CO2Supercritical extract is prepared from, described overcritical
The temperature that extraction is used is 20-40MPa for 25-35 DEG C, pressure.
High using lycopene oleoresin active component content made from the technique, oxidation material content is few, to prescription
Synergy is more favourable.
Preferably, the pumpkin seed oil include the black alcohol of oleic acid, linoleic acid, palmitic acid, stearic acid, plant, vitamin E and
Carotenoid；Wherein, weight percentage, oleic acid accounting >=30%, linoleic acid accounting >=50%, palmitic acid accounting >=
10%, stearic acid accounting >=8%.
The pumpkin seed oil of the quality can be through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, described super to face
The temperature that boundary's extraction is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, pumpkin is after ultramicro grinding, and the particle diameter of pumpkin powder is less than 100 μm, and powder diameter is uniform, carefully
Cell wall is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2The temperature that supercritical extraction is used
For normal temperature, pumpkin is in CO2Atmosphere in, should under the conditions of can ensure that the active component in pumpkin is particularly temperature sensitive
Active material and oxidizable active material do not degraded by high-temperature oxygen, and the recovery rate of active component is high, obtains
Pumpkin seed oil quality better.
The ganoderma lucidum spore oil includes following component：Triterpenes aliphatic acid, unrighted acid, organic germanium and ganoderma lucidum are more
Sugar.
The ganoderma lucidum spore oil of the quality is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, described super to face
The temperature that boundary's extraction is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, lucidum spore powder is after ultramicro grinding, and the particle diameter of Reishi sporule powder is less than 100 μm, powder diameter
Uniformly, cell membrane is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2Supercritical extraction is used
Temperature be normal temperature, Reishi sporule is in CO2Atmosphere in, should under the conditions of can ensure that the active component in Reishi sporule is particularly
Thermally sensitive active material and oxidizable active material are not degraded by high-temperature oxygen, and the extraction of active component
Rate is high, obtained ganoderma lucidum spore oil quality better.
There is low recovery rate, dissolvent residual, active component in squeezing, the organic solvent extraction of routine, and
CO of the present invention2Supercritical extraction process completely avoid problem above.
Wherein, degumming, depickling for example can add alkali depickling (to be determined with crude oil acid value after alkali number, plus alkali using conventional means
Need to stir 10 minutes with 90rpm speed), heating is needed in deacidification, and heating rate preferably is 1 DEG C/min.
For formulation, although the present invention can be made into the formulations such as tablet, pill, paste or capsule in theory, but be due to
The main component of the present invention is oils, therefore, is advisable with soft capsule, its absorptivity and stability are higher.
By taking soft capsule as an example, immunity enhancing effect can also be improved indirectly in terms of health products absorptivity, stability
Really, for example：
Preferably, complex health care product also includes pharmaceutically acceptable emulsifying agent 5-20 parts.
When emulsifying agent adds excessive, the absorptivity of health products can be reduced on the contrary, influence health-care effect.It is tests determined, plus
Enter 5-20 parts of emulsifying agents to be advisable.
It is preferred that emulsifying agent be beeswax, its be pure natural food materials, it is safe and harmless, and can significantly improve immunity enhancing work(
Effect.
The capsule shells that soft capsule of the prior art is used are generally the formula containing pigment, but pigment is in the presence of more or less
Side effect, therefore, the invention provides following capsule shells formula：By weight,
200-500 parts of gelatin,
150-300 parts of glycerine,
250-500 parts of purified water.
Compared with prior art, capsule shells of the invention formula is simpler, safe., can if considering lucifuge demand certainly
To solve by other means, for example, change the color of outer packing, so both met lucifuge needs, and turn avoid introducing pigment
Deng hypotoxicity raw material.As example, if any other side demand, then as far as possible not to edible part addition exogenous material, and
It is improved on packing.
In the formula of above-mentioned capsule shells, the content of each composition can also be improved further, to improve stability, for example：
Gelatin is preferred 400-500 parts, and glycerine is preferred 150-200 parts, and purified water is preferred 400-500 parts.
The capsule shells can use following preparation method：First glycerine, purified water are mixed, gained mixture after gelatin is added
Stirred 1-2 hours at 65-75 DEG C, then stand 2-3 hours, cast molding afterwards obtains rubber, is molded using capsule machine pelleting.
To sum up, compared with prior art, the present invention achieves following technique effect：
(1) by lycopene oleoresin, pumpkin seed oil, four kinds of composition scientific compatibilities of ganoderma lucidum spore oil and vitamin E, occur
Collaboration, significantly enhances body immunity, can effectively strengthen prevention and suppress the effect of tumour generation, especially to prostate cancer
Prevention and suppression；
(2) auxiliary material of science species and proportioning is introduced, the absorptivity of health products is improved, so as to improve immunity indirectly
Enhancing effect；
(3) pigment conventional in capsule shells is removed, the security of health products is improved；
(4) by improving CO2The operating condition of supercritical extraction process, not only improves the ratio of main active component in oil
Example, and avoid introduce caused by the material such as organic solvent a series of problems (for example remove solvent cost, it is blowdown flow rate, molten
Agent residual etc.)；
(5) yield and quality of lycopene oleoresin are improved by improving the extraction process of lycopene.
Embodiment
Technical scheme is clearly and completely described below in conjunction with embodiment, but ability
Field technique personnel will be understood that following described embodiment is a part of embodiment of the invention, rather than whole embodiments,
The present invention is merely to illustrate, and is not construed as limiting the scope of the present invention.Based on the embodiment in the present invention, the common skill in this area
The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model that the present invention is protected
Enclose.Unreceipted actual conditions person in embodiment, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or instrument
Unreceipted production firm person, is the conventional products that can be obtained by commercially available purchase.
Embodiment 1
Pumpkin seed oil is extracted from pumpkin：
1st, pre-process：Pumpkin is cleaned, dust and other impurity is screened out.
2、CO2Supercritical extract：Temperature be 25 DEG C, pressure be to extract once under conditions of 30MPa or so, collect respectively
Oil and the dregs of fat.
3rd, degumming, depickling：Plus alkali depickling, determine to need after alkali number, plus alkali with crude oil acid value to stir 10 with 90rpm speed
Minute, heated in deacidification with 1 DEG C/min heating rates.
As a result：
Gained pumpkin seed oil includes the black alcohol of oleic acid, linoleic acid, palmitic acid, stearic acid, plant, vitamin E and carotenoids
Element；Wherein, by weight, oleic acid accounting is 30%, and linoleic acid accounting is 52%, and palmitic acid accounting is 10%, stearic acid accounting
For 8%.
Embodiment 2
Pumpkin seed oil is extracted from pumpkin：
1st, pre-process：Pumpkin is cleaned, dust and other impurity is screened out.
2、CO2Supercritical extract：Temperature be 35 DEG C, pressure be to extract once under conditions of 20MPa, collect respectively oil and
The dregs of fat.
3rd, degumming, depickling：Plus alkali depickling, determine to need after alkali number, plus alkali with crude oil acid value to stir 10 with 90rpm speed
Minute, heated in deacidification with 1 DEG C/min heating rates.
As a result：
Gained pumpkin seed oil includes the black alcohol of oleic acid, linoleic acid, palmitic acid, stearic acid, plant, vitamin E and carotenoids
Element；Wherein, by weight, oleic acid accounting is 31%, and linoleic acid accounting is 51%, and palmitic acid accounting is 10%, stearic acid accounting
For 8%.
Embodiment 3
Ganoderma lucidum spore oil is extracted from Reishi sporule：
The composition of detection gained ganoderma lucidum spore oil is more containing triterpenes aliphatic acid, unrighted acid, organic germanium and ganoderma lucidum
Sugar.
Embodiment 4
Prepare lycopene oleoresin：
1st, pre-process：The tomato skin of drying and ripening is cleaned, dust and other impurity is screened out, then crush.
2、CO2Supercritical extract：Temperature be 25 DEG C, pressure be to carry out CO under conditions of 25MPa2Supercritical extract.
Embodiment 5
Prepare lycopene oleoresin：
1st, pre-process：The tomato skin of drying and ripening is cleaned, dust and other impurity is screened out, then crush.
2、CO2Supercritical extract：Temperature be 35 DEG C, pressure be to carry out CO under conditions of 40MPa2Supercritical extract.
Embodiment 6
Prepare capsule shells：
1st, feeding：Gelatin 400g, glycerine 200g, purified water 250g.
2nd, prepare：First glycerine, purified water are mixed, gained mixture after gelatin is added and is stirred 2 hours at 65 DEG C, then it is quiet
Put 3 hours, cast molding afterwards obtains rubber, be molded using capsule machine pelleting.
Embodiment 7
From embodiment 6 to differ only in formula different, be：Gelatin 500g, glycerine 150g, purified water 500g.
Embodiment 8
Prepare complex health care product：
1st, draw materials：Lycopene oleoresin (gained of embodiment 5) 150g, pumpkin seed oil 250g, ganoderma lucidum spore oil 50g, dimension
Raw element E10g, beeswax 15g.
2nd, capsule is prepared：All raw materials in 1st step are mixed, homogeneous, in the capsule shells that the offer of embodiment 7 is provided.
Embodiment 9
From embodiment 8 to differ only in beeswax consumption different, be 20g.
Embodiment 10
It is different from the proportioning for differing only in primary raw material of embodiment 8, i.e. lycopene oleoresin, pumpkin seed oil, spirit
The proportioning of Ganoderma lucidum spore oil and vitamin E, be：Lycopene oleoresin 200g, pumpkin seed oil 200g, ganoderma lucidum spore oil 70g, dimension life
Plain E5g, beeswax 5g.
Embodiment 11
It is different from the proportioning for differing only in primary raw material of embodiment 8, i.e. lycopene oleoresin, pumpkin seed oil, spirit
The proportioning of Ganoderma lucidum spore oil and vitamin E, be：Lycopene oleoresin 100g, pumpkin seed oil 300g, ganoderma lucidum spore oil 30g, dimension life
Plain E20g, beeswax 15g.
Embodiment 12
With differing only in without beeswax for embodiment 8.
Comparative example 1
Different from the proportioning for differing only in primary raw material of embodiment 9, i.e., proportioning is：Lycopene oleoresin
210g, pumpkin seed oil 180g, ganoderma lucidum spore oil 75g, vitamin e1 0g, beeswax 10g.
Comparative example 2
Comparative example 2 is commercially available lycopene oleoresin and pumpkin seed oil in mass ratio 3:5 are made into, the same comparative example of manufacturing process
1。
Comparative example 3
Comparative example 3 is commercially available pumpkin seed oil and ganoderma lucidum spore oil in mass ratio 5:1 is made into, and manufacturing process is with comparative example 1.
Comparative example 4
Comparative example 4 is commercially available lycopene oleoresin and commercially available ganoderma lucidum spore oil in mass ratio 3:1 is made into, and manufacturing process is same
Comparative example 1.
Comparative example 5
Comparative example 5 is commercially available lycopene oleoresin, pumpkin seed oil and ganoderma lucidum spore oil in mass ratio 3:5:1 is made into, system
Make process with comparative example 1.
Comparative example 6
Comparative example 6 is made with reference to the embodiment 1 in patent application CN102727872A.
Comparative example 7
Comparative example 7 is different from the source for differing only in lycopene oleoresin of embodiment 9, with reference to patent application
CN103948565A embodiment 1.
It is limited that standing grain biotechnology is good in commercially available lycopene oleoresin producer Shijiazhuang used in the comparative example of the present invention
Company, the global natural perfume material Co., Ltd in commercially available pumpkin seed oil producer Jiangxi, commercially available ganoderma lucidum spore oil producer Guangzhou Jingjing is biological
Science and Technology Ltd..
Influence of the experimental example health products to immune function of mice
1st, the present invention promotes helper T lymphocyte (Th cells) propagation
Experimental animal：Healthy female or male mice, 18~22g of body weight, 4 week old.
A. experimental animal continuous gavage is administered 10 days, dosage such as table 1 below：
Table 1
B. the 11st day, after sterile separating mouse spleen cell, 70%Percoll density gradient centrifugations is used, single core is obtained
Cell suspension；
C. anti-CD4+T fluorescent labeled antibodies are added, single CD4+T cells are obtained by selected by flow cytometry apoptosis；
D.96 hole cel culture plates, 5 × 106/ mL is inoculated with；
E. after incubator culture 48h, WST methods detection cell proliferative conditions.
The different health products of the present invention are stimulated into CD4+T lymphocyte 48h, its stimulation situation is detected.Experimental result is shown：
Compared with negative control group and positive controls, senior middle school's low dosages of various embodiments of the present invention (20mg/kg, 40mg/kg and
60mg/kg) mouse spleen mononuclearcell can be promoted to breed and there is statistical significance, increase rate is more than 8.2% (with life
Manage the contrast of salt solution group).Comparing embodiment 8 to 11 can be found with embodiment 12, and immunologic function is significantly improved after addition beeswax.Than
It is more of the invention to be found with comparative example 1, in formula species under the same conditions, if the proportioning of composition is different, the guarantor reached
Strong effect difference is larger.Each health products are as shown in table 2 to the proliferation rate of T cell under middle dosage compared to physiological saline.
Table 2
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that：Its according to
The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered
Row equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of complex health care product of strengthen immunity, it is characterised in that be mainly made up of following component：By weight,
2. complex health care product according to claim 1, it is characterised in that by weight,
3. complex health care product according to claim 1, it is characterised in that the lycopene oleoresin through ultramicro grinding,
CO2Supercritical extract is prepared from, and the temperature that the supercritical extraction is used is 20-40MPa for 25-35 DEG C, pressure.
4. complex health care product according to claim 1, it is characterised in that the pumpkin seed oil include oleic acid, linoleic acid,
The black alcohol of palmitic acid, stearic acid, plant, vitamin E and carotenoid；Wherein, weight percentage, oleic acid accounting >=
30%, linoleic acid accounting >=50%, palmitic acid accounting >=10%, stearic acid accounting >=8%；
Preferably, the pumpkin seed oil is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the overcritical extraction
It is 20-40MPa for 25-35 DEG C, pressure to follow the example of the temperature used.
5. complex health care product according to claim 1, it is characterised in that the ganoderma lucidum spore oil includes following component：Three
Terpene aliphatic acid, unrighted acid, organic germanium and GL-B；
Preferably, the ganoderma lucidum spore oil is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, described overcritical
The temperature that extraction is used is 20-40MPa for 25-35 DEG C, pressure.
6. complex health care product according to claim 1, it is characterised in that the formulation of the complex health care product is soft capsule
Agent.
7. complex health care product according to claim 6, it is characterised in that also contain emulsifying agent in the soft capsule, described
The consumption of emulsifying agent is preferably 5-20 parts.
8. complex health care product according to claim 7, it is characterised in that the emulsifying agent is beeswax.
9. complex health care product according to claim 6, it is characterised in that soft capsule shell master used in the soft capsule
To be made up of following component：By weight,
200-500 parts of gelatin, preferably 400-500 parts,
150-300 parts of glycerine, preferably 150-200 parts,
250-500 parts, preferably 400-500 parts of purified water.
10. complex health care product according to claim 9, it is characterised in that the preparation method of the soft capsule shell is：First will
Glycerine, purified water mixing, add gained mixture after gelatin and are stirred 1-2 hours at 65-75 DEG C, then stand 2-3 hours, afterwards
Cast molding obtains rubber, is molded using capsule machine pelleting.
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| CN201710481065.6A CN107232594A (en) | 2017-06-22 | 2017-06-22 | A kind of complex health care product of strengthen immunity |
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Cited By (5)
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| CN108669557A (en) * | 2018-05-20 | 2018-10-19 | 苏州工业园区联创生物科技有限公司 | Soft capsule dosage form and preparation method thereof containing natural tomato extract liquor pumpkin seed oil |
| WO2020113495A1 (en) * | 2018-12-06 | 2020-06-11 | 江苏安惠生物科技有限公司 | Soft ganoderma lucidum spore oil capsule |
| WO2022105726A1 (en) * | 2020-11-18 | 2022-05-27 | 中科健康产业集团股份有限公司 | Production method for lycopene-containing granules with efficient antioxidation effect |
| WO2022142791A1 (en) * | 2020-12-29 | 2022-07-07 | 中科健康产业集团股份有限公司 | Method for preparing lycopene composition with anti-aging effect |
| CN116035076A (en) * | 2022-10-12 | 2023-05-02 | 五指山黎苗不老食品有限公司 | Functional passion fruit seed blend oil and preparation method thereof |
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| CN116035076A (en) * | 2022-10-12 | 2023-05-02 | 五指山黎苗不老食品有限公司 | Functional passion fruit seed blend oil and preparation method thereof |
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Application publication date: 20171010 |