CN106266252A - A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof - Google Patents

A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof Download PDF

Info

Publication number
CN106266252A
CN106266252A CN201610717170.0A CN201610717170A CN106266252A CN 106266252 A CN106266252 A CN 106266252A CN 201610717170 A CN201610717170 A CN 201610717170A CN 106266252 A CN106266252 A CN 106266252A
Authority
CN
China
Prior art keywords
lycopene
soft capsule
oleum camelliae
parts
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610717170.0A
Other languages
Chinese (zh)
Inventor
黄浩
邹芬兰
程勇
龚小保
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gannan Medical University
Original Assignee
Gannan Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gannan Medical University filed Critical Gannan Medical University
Priority to CN201610717170.0A priority Critical patent/CN106266252A/en
Publication of CN106266252A publication Critical patent/CN106266252A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention belongs to field of medicine preparing technology, it particularly relates to a kind of lycopene Oleum Camelliae soft capsule and preparation method thereof.The content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, the lycopene of 4 15 parts and the suspending agent of 0.2 4 parts;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticizer of 30 60 parts, the disintegrating agent of 5 10 parts, the coloring agent of 0.1 0.5 parts and the opacifier of 0.1 1 parts.Compared with prior art, lycopene Oleum Camelliae soft capsule of the present invention have the advantage that by by miscible for lycopene in a large amount of Oleum Camelliae, make oxygen only contact with Oleum Camelliae, thus with lycopene completely cut off;Oleum Camelliae is mainly composed of unsaturated fatty acid, can be used as antioxidant, and the product after aoxidizing is the satisfied fatty acid still can taken.

Description

A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof
Technical field
The invention belongs to field of medicine preparing technology, it particularly relates to a kind of lycopene Oleum Camelliae soft capsule and Preparation method.
Background technology
Oleum Camelliae is the edible oil that wild camellia seed refines, and has another name called camellia seed oil, Camellia oil.The unsaturated fatty acid of Oleum Camelliae Amount is more than 85%, and vitamin A and E content are high, and storage tolerance, easily it is absorbed by the body.Oleum Camelliae is without harmful mustard Acid, moreover it is possible to prevent and treat hypertension, cardiovascular disease, be the outstanding person in edible vegetable oil.Industrially, Oleum Camelliae can be produced Oleic acid and esters, production soap and vaseline etc., it is possible to make stearic acid and glycerol.Pharmaceutically, Oleum Camelliae can be used for making Injection and modulation various ointment, pill etc., among the people also with Oleum Camelliae treatment scald and burn and the skin such as tinea corporis, chronic eczema Sick.
Lycopene (Lycopene) is a kind of natural pigment contained in plant, is primarily present in plant of Solanaceae Fructus Lycopersici esculenti Mature fruit in, it also has in red fruit such as Citrullus vulgaris and Citrua paradiai, is the most common and the strongest Carotenoids Isolated of human body One of oxygen agent.The research of decades confirms: lycopene is 5~10mg/ days for the health care amount of normal population, sick for some Suffer from crowd's such as prostate, enhancing fertility, blood fat reducing, radioprotective etc. and then need 20-30mg/ days;Some consumers take after also Not feeling the value place of lycopene, main cause is exactly that the lycopene effective dose taken is the lowest.
In the formulation, lycopene does not only have the requirement of certain content.And, lycopene is unsaturated compound, pole The most oxidized, quality is unstable, it is difficult to effect of bringing into normal play.Just because of this, the soft capsule of lycopene that prior art is made is normal There is insoluble matter, it is impossible to meet formulation requirements.Lycopene and Oleum Camelliae are as health product, though gaining great popularity, but both of which is independent Use.At present, we attempt, by lycopene and Oleum Camelliae use in conjunction, to strengthen drug effect, reducing or remitting defect, but by facing upward with Jiangxi The cooperation of Shan Yuan oil tea development corporation, Ltd. finds, lycopene dissolubility in Oleum Camelliae is extremely low.
Summary of the invention
For solving above-mentioned technical problem, the invention provides a kind of dissolubility lycopene Oleum Camelliae good, stay-in-grade soft Capsule and preparation method thereof.
A kind of lycopene Oleum Camelliae soft capsule of the present invention, the content of described soft capsule in parts by mass, including Oleum Camelliae, the lycopene of 4-15 part and the suspending agent of 0.2-4 part of 100 parts;The capsule material of described soft capsule in parts by mass, including Gelatin, the plasticizer of 30-60 part, the disintegrating agent of 5-10 part, the coloring agent of 0.1-0.5 part and the shading of 0.1-1 part of 100 parts Agent.
A kind of lycopene Oleum Camelliae soft capsule of the present invention, described suspending agent is Cera Flava, double protocatechuic acid glycosides, ethyl Cellulose or aluminum monostearate.
A kind of lycopene Oleum Camelliae soft capsule of the present invention, described plasticizer is glycerol;Described opacifier is oxidation Ferrum or titanium white.
A kind of lycopene Oleum Camelliae soft capsule of the present invention, described disintegrating agent is cyclodextrin, sorbitol or poly-second two Alcohol.
A kind of lycopene Oleum Camelliae soft capsule of the present invention, described coloring agent is that curcumin, amaranth or red rice are red.
The preparation method of a kind of lycopene Oleum Camelliae soft capsule of the present invention, described preparation method specifically includes as follows Step:
1) taking Oleum Camelliae, lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the material of content Liquid;
2) take plasticizer, add the purified water of 1-1.5 times of gelatin amount, 70-80 degree heating for dissolving, add disintegrating agent, coloring agent And opacifier, after stirring, it being subsequently adding gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes softgel shell Glue, 60 degree of insulations, stand-by;
3) being placed in soft capsule pellet press by the glue of the feed liquid of content Yu softgel shell respectively, be pressed into soft capsule, content is every Grain dress 0.5g.
Compared with prior art, lycopene Oleum Camelliae soft capsule of the present invention has the advantage that by by Fructus Lycopersici esculenti Red pigment is miscible in a large amount of Oleum Camelliae, makes oxygen only contact with Oleum Camelliae, thus completely cuts off with lycopene;Oleum Camelliae is mainly composed of insatiable hunger And fatty acid, can be used as antioxidant, and the product after aoxidizing is the satisfied fatty acid still can taken.
Detailed description of the invention
Below in conjunction with specific embodiment lycopene Oleum Camelliae soft capsule of the present invention and preparation method thereof done into One step explanation, but protection scope of the present invention is not limited to this.
Embodiment 1
A kind of lycopene Oleum Camelliae soft capsule, the content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, 4 parts Lycopene and the suspending agent of 0.2 part;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticising of 30 parts Agent, the disintegrating agent of 5 parts, the coloring agent of 0.1 part and the opacifier of 0.1 part.Described suspending agent is Cera Flava.Described plasticizer is sweet Oil;Described opacifier is ferrum oxide.Described disintegrating agent is cyclodextrin.Described coloring agent is curcumin.
The preparation method of lycopene Oleum Camelliae soft capsule, described preparation method specifically includes following steps: 1) take Oleum Camelliae, kind Lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the feed liquid of content;2) take plasticizer, add Enter the purified water of 1 times of gelatin amount, 70 degree of heating for dissolving, add disintegrating agent, coloring agent and opacifier, after stirring, then Adding gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes the glue of softgel shell, and 60 degree of insulations are stand-by;3) respectively The glue of the feed liquid of content Yu softgel shell is placed in soft capsule pellet press, is pressed into soft capsule, content every dress 0.5g.
Embodiment 2
A kind of lycopene Oleum Camelliae soft capsule, the content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, 15 parts Lycopene and the suspending agent of 4 parts;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticising of 60 parts Agent, the disintegrating agent of 10 parts, the coloring agent of 0.5 part and the opacifier of 1 part.Described suspending agent is aluminum monostearate.Described plasticizer For glycerol;Described opacifier is titanium white.Described disintegrating agent is sorbitol.Described coloring agent is amaranth.
The preparation method of lycopene Oleum Camelliae soft capsule, described preparation method specifically includes following steps: 1) take Oleum Camelliae, kind Lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the feed liquid of content;2) take plasticizer, add Enter the purified water of 1.5 times of gelatin amounts, 80 degree of heating for dissolving, add disintegrating agent, coloring agent and opacifier, after stirring, so Rear addition gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes the glue of softgel shell, and 60 degree of insulations are stand-by;3) divide The glue of the feed liquid of content Yu softgel shell is not placed in soft capsule pellet press, is pressed into soft capsule, content every dress 0.5g.
Embodiment 3
A kind of lycopene Oleum Camelliae soft capsule, the content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, 8 parts Lycopene and the suspending agent of 1 part;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticising of 45 parts Agent, the disintegrating agent of 8 parts, the coloring agent of 0.3 part and the opacifier of 0.5 part.Described suspending agent is ethyl cellulose.Described plasticizer For glycerol;Described opacifier is titanium white.Described disintegrating agent is cyclodextrin.Described coloring agent is that red rice is red.
The preparation method of lycopene Oleum Camelliae soft capsule, described preparation method specifically includes following steps: 1) take Oleum Camelliae, kind Lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the feed liquid of content;2) take plasticizer, add Enter the purified water of 1.2 times of gelatin amounts, 75 degree of heating for dissolving, add disintegrating agent, coloring agent and opacifier, after stirring, so Rear addition gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes the glue of softgel shell, and 60 degree of insulations are stand-by;3) divide The glue of the feed liquid of content Yu softgel shell is not placed in soft capsule pellet press, is pressed into soft capsule, content every dress 0.5g.
Embodiment 4
A kind of lycopene Oleum Camelliae soft capsule, the content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, 8 parts Lycopene and the suspending agent of 1 part;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticising of 45 parts Agent, the disintegrating agent of 8 parts, the coloring agent of 0.3 part and the opacifier of 0.5 part.Described suspending agent is double protocatechuic acid glycosides.Described plasticising Agent is glycerol;Described opacifier is titanium white.Described disintegrating agent is cyclodextrin.Described coloring agent is that red rice is red.
The preparation method of lycopene Oleum Camelliae soft capsule, described preparation method specifically includes following steps: 1) take Oleum Camelliae, kind Lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the feed liquid of content;2) take plasticizer, add Enter the purified water of 1.2 times of gelatin amounts, 75 degree of heating for dissolving, add disintegrating agent, coloring agent and opacifier, after stirring, so Rear addition gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes the glue of softgel shell, and 60 degree of insulations are stand-by;3) divide The glue of the feed liquid of content Yu softgel shell is not placed in soft capsule pellet press, is pressed into soft capsule, content every dress 0.5g.
Embodiment 5
A kind of lycopene Oleum Camelliae soft capsule, the content of described soft capsule in parts by mass, including the Oleum Camelliae of 100 parts, 15 parts Lycopene and the suspending agent of 4 parts;The capsule material of described soft capsule in parts by mass, including the gelatin of 100 parts, the plasticising of 60 parts Agent, the disintegrating agent of 10 parts, the coloring agent of 0.5 part and the opacifier of 1 part.Described suspending agent is double protocatechuic acid glycosides.Described plasticising Agent is glycerol;Described opacifier is titanium white.Described disintegrating agent is sorbitol.Described coloring agent is amaranth.
The preparation method of lycopene Oleum Camelliae soft capsule, described preparation method specifically includes following steps: 1) take Oleum Camelliae, kind Lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the feed liquid of content;2) take plasticizer, add Enter the purified water of 1.5 times of gelatin amounts, 80 degree of heating for dissolving, add disintegrating agent, coloring agent and opacifier, after stirring, so Rear addition gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes the glue of softgel shell, and 60 degree of insulations are stand-by;3) divide The glue of the feed liquid of content Yu softgel shell is not placed in soft capsule pellet press, is pressed into soft capsule, content every dress 0.5g.
Effect experiment
Aged (more than 12 monthly ages) Kunming mouse 90, body weight 30-50g, male and female half and half, it is randomly divided into 9 groups, often group 10.9 Group correspond to respectively: normal group, model group, matched group 1(lack the embodiment 4 after lycopene), matched group 2(soybean oil replace Embodiment 4 after Oleum Camelliae), embodiment 1, embodiment 2, embodiment 3, embodiment 4 and embodiment 5.In addition to normal group, other 8 groups It is AlCl3Model of Dementia.Each administration group respectively by body weight converting doses gavage, every day gavage 1 time, and successive administration 30 days, Heart extracting blood after last administration 4h.Utilize various antioxidation test kit, detect in each group of sample serum classical anti-respectively Aging index composition, including malonaldehyde (MDA), glutathion peroxidase (GSH-Px) and superoxide dismutase (SOD). Testing result is shown in Table 1.
The impact on mice defying age index components of the table 1:7 group soft capsule

Claims (6)

1. a lycopene Oleum Camelliae soft capsule, it is characterised in that the content of described soft capsule in parts by mass, including 100 Oleum Camelliae, the lycopene of 4-15 part and the suspending agent of 0.2-4 part of part;The capsule material of described soft capsule in parts by mass, including 100 Gelatin, the plasticizer of 30-60 part, the disintegrating agent of 5-10 part, the coloring agent of 0.1-0.5 part and the opacifier of 0.1-1 part of part.
Lycopene Oleum Camelliae soft capsule the most according to claim 1, it is characterised in that described suspending agent is Cera Flava, double former Catechuic acid glycosides, ethyl cellulose or aluminum monostearate.
Lycopene Oleum Camelliae soft capsule the most according to claim 1, it is characterised in that described plasticizer is glycerol;Described Opacifier is ferrum oxide or titanium white.
Lycopene Oleum Camelliae soft capsule the most according to claim 1, it is characterised in that described disintegrating agent is cyclodextrin, mountain Pears alcohol or Polyethylene Glycol.
Lycopene Oleum Camelliae soft capsule the most according to claim 1, it is characterised in that described coloring agent is curcumin, Herba Amaranthi tricoloris Dish is red or red rice is red.
The preparation method of lycopene Oleum Camelliae soft capsule the most according to claim 1, it is characterised in that described preparation method Specifically include following steps:
1) taking Oleum Camelliae, lycopene and suspending agent, stirring makes its mix homogeneously, and evacuation takes off bubble, makes the material of content Liquid;
2) take plasticizer, add the purified water of 1-1.5 times of gelatin amount, 70-80 degree heating for dissolving, add disintegrating agent, coloring agent And opacifier, after stirring, it being subsequently adding gelatin heating 1h, 100 mesh screen, evacuation takes off bubble, makes softgel shell Glue, 60 degree of insulations, stand-by;
3) being placed in soft capsule pellet press by the glue of the feed liquid of content Yu softgel shell respectively, be pressed into soft capsule, content is every Grain dress 0.5g.
CN201610717170.0A 2016-08-25 2016-08-25 A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof Pending CN106266252A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610717170.0A CN106266252A (en) 2016-08-25 2016-08-25 A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610717170.0A CN106266252A (en) 2016-08-25 2016-08-25 A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof

Publications (1)

Publication Number Publication Date
CN106266252A true CN106266252A (en) 2017-01-04

Family

ID=57615074

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610717170.0A Pending CN106266252A (en) 2016-08-25 2016-08-25 A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof

Country Status (1)

Country Link
CN (1) CN106266252A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107348304A (en) * 2017-07-21 2017-11-17 郑州博凯医药保健品有限公司 Effervescent tablet containing Tea Polyphenols and curcumin and preparation method thereof
CN109430847A (en) * 2018-12-04 2019-03-08 安徽省金天柱农业科技有限公司 A kind of tea oil soft capsule and preparation method thereof
CN111991365A (en) * 2020-08-15 2020-11-27 盈姿生物科技(上海)有限公司 Lycopene soft capsule and preparation method thereof
CN113575948A (en) * 2021-08-04 2021-11-02 上海健康医学院 Lycopene soft capsule and preparation method and application thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1823762A (en) * 2005-12-21 2006-08-30 国家纳米技术产业化基地 Chuanxiong lactone kind component soft capsule for treating cardiovascular and cerebrovascular diseases
CN101496796A (en) * 2008-01-29 2009-08-05 北京康必得药业有限公司 Composite soft capsule of lycopene
CN105660885A (en) * 2016-01-07 2016-06-15 伊国群 Natural nutriment with function of regulating blood lipid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1823762A (en) * 2005-12-21 2006-08-30 国家纳米技术产业化基地 Chuanxiong lactone kind component soft capsule for treating cardiovascular and cerebrovascular diseases
CN101496796A (en) * 2008-01-29 2009-08-05 北京康必得药业有限公司 Composite soft capsule of lycopene
CN105660885A (en) * 2016-01-07 2016-06-15 伊国群 Natural nutriment with function of regulating blood lipid

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张寿山: "《制药厂生产车间新技术新工艺流程与操作技能应用、质量控制设备运行维护实用全书 第2册》", 31 October 2005, 中国医药科技电子出版社 *
谢美萍等: ""狗脊中的酚酸及其苷类成分"", 《中草药》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107348304A (en) * 2017-07-21 2017-11-17 郑州博凯医药保健品有限公司 Effervescent tablet containing Tea Polyphenols and curcumin and preparation method thereof
CN107348304B (en) * 2017-07-21 2024-02-09 博凯药业有限公司 Effervescent tablet containing tea polyphenols and curcumin and its preparation method
CN109430847A (en) * 2018-12-04 2019-03-08 安徽省金天柱农业科技有限公司 A kind of tea oil soft capsule and preparation method thereof
CN111991365A (en) * 2020-08-15 2020-11-27 盈姿生物科技(上海)有限公司 Lycopene soft capsule and preparation method thereof
CN113575948A (en) * 2021-08-04 2021-11-02 上海健康医学院 Lycopene soft capsule and preparation method and application thereof
CN113575948B (en) * 2021-08-04 2024-01-26 上海健康医学院 Lycopene soft capsule and preparation method and application thereof

Similar Documents

Publication Publication Date Title
Tang et al. Vitamin A, nutrition, and health values of algae: Spirulina, Chlorella, and Dunaliella
CN104306617B (en) Composition containing maca and A Sayi fruits and its preparation method and application
CN106266252A (en) A kind of lycopene Oleum Camelliae soft capsule and preparation method thereof
CN103652859B (en) A kind of health food with anti-oxidation function and preparation method thereof
CN107441236A (en) A kind of Astaxanthin In Haematococcus Pluvialis liver protecting product and preparation method thereof
CN104274509A (en) Health product composition containing cordyceps sinensis and male flower of eucommia ulmoides as well as preparation method and application of health product composition
CN103349711B (en) Anti-aging combination with resveratrol and preparation method thereof
CN105707637A (en) Solid beverage capable of reduce blood glucose, and preparation method thereof
CN106550970A (en) A kind of Tartary buckwheat cake
CN104957603B (en) Improving memory type nutritious supplementary and its preparation method
JPS6042485A (en) Antioxidant
CN104799286A (en) Composition for improving immunity and preparation method of composition
CN106107997A (en) A kind of antioxidation hypertension and hyperlipemia SOD Semen Lini oil soft capsule and preparation method thereof
CN112156143A (en) Compound nutrient composition with antioxidant function
CN104920967B (en) Relieving alcoholism and protecting liver type nutritious supplementary and its preparation method
CN103610048B (en) To chemical damage health food having assistant protection function and preparation method thereof
CN106309917B (en) A kind of anti-aging, the compound preparation for preventing cardiovascular and cerebrovascular disease and preparation method thereof
CN105231447A (en) Health-care lycium ruthenicum tablets capable of alleviating asthenopia
CN102100846B (en) Chinese medicinal composition with function of relieving physical fatigue and preparation method thereof
KR20100090366A (en) Turmeric. Red ginseng. Supplementary food supplemented with 37 kinds of Sanyang Sansam
CN104055115B (en) A kind of health products containing agate coffee, the stem of noble dendrobium and Panax Japonicus Var. Major and preparation method thereof
CN105901722A (en) Euphausia superba oil healthcare capsule for preventing Alzheimer's disease
CN102552324A (en) Novel technique for preparing natural donkey-hide gelatin
CN102106930B (en) Mixture with antioxidant and liver-protecting functions and manufacturing method thereof
LU500683B1 (en) Purpose of Composition Comprising Black Hulless Barley and Black Quinoa in Preparation of Anti-oxidation Products

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20170104

WD01 Invention patent application deemed withdrawn after publication