CN105231447A - Health-care lycium ruthenicum tablets capable of alleviating asthenopia - Google Patents
Health-care lycium ruthenicum tablets capable of alleviating asthenopia Download PDFInfo
- Publication number
- CN105231447A CN105231447A CN201510711969.4A CN201510711969A CN105231447A CN 105231447 A CN105231447 A CN 105231447A CN 201510711969 A CN201510711969 A CN 201510711969A CN 105231447 A CN105231447 A CN 105231447A
- Authority
- CN
- China
- Prior art keywords
- health
- black fruit
- fruit lyceum
- care
- extract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000169546 Lycium ruthenicum Species 0.000 title abstract description 11
- 208000003464 asthenopia Diseases 0.000 title abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 28
- 235000018290 Musa x paradisiaca Nutrition 0.000 claims abstract description 14
- 238000002360 preparation method Methods 0.000 claims abstract description 8
- 235000013399 edible fruits Nutrition 0.000 claims description 61
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 241000234295 Musa Species 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 12
- 235000019890 Amylum Nutrition 0.000 claims description 12
- 108010010803 Gelatin Proteins 0.000 claims description 12
- 239000002202 Polyethylene glycol Substances 0.000 claims description 12
- 229920002472 Starch Polymers 0.000 claims description 12
- 229920000159 gelatin Polymers 0.000 claims description 12
- 239000008273 gelatin Substances 0.000 claims description 12
- 235000019322 gelatine Nutrition 0.000 claims description 12
- 235000011852 gelatine desserts Nutrition 0.000 claims description 12
- 229940037627 magnesium lauryl sulfate Drugs 0.000 claims description 12
- HBNDBUATLJAUQM-UHFFFAOYSA-L magnesium;dodecyl sulfate Chemical compound [Mg+2].CCCCCCCCCCCCOS([O-])(=O)=O.CCCCCCCCCCCCOS([O-])(=O)=O HBNDBUATLJAUQM-UHFFFAOYSA-L 0.000 claims description 12
- 229920001223 polyethylene glycol Polymers 0.000 claims description 12
- 235000010413 sodium alginate Nutrition 0.000 claims description 12
- 239000000661 sodium alginate Substances 0.000 claims description 12
- 229940005550 sodium alginate Drugs 0.000 claims description 12
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 12
- 239000004299 sodium benzoate Substances 0.000 claims description 12
- 235000010234 sodium benzoate Nutrition 0.000 claims description 12
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 9
- 239000012467 final product Substances 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 239000008213 purified water Substances 0.000 claims description 7
- 239000002994 raw material Substances 0.000 claims description 7
- 238000000605 extraction Methods 0.000 claims description 6
- 238000005238 degreasing Methods 0.000 claims description 5
- 239000000686 essence Substances 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 5
- 239000003208 petroleum Substances 0.000 claims description 5
- 238000002390 rotary evaporation Methods 0.000 claims description 5
- 239000011122 softwood Substances 0.000 claims description 5
- 235000020985 whole grains Nutrition 0.000 claims description 5
- 238000011017 operating method Methods 0.000 claims description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 238000012545 processing Methods 0.000 abstract description 2
- 240000005561 Musa balbisiana Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 8
- 238000000034 method Methods 0.000 description 6
- 239000000049 pigment Substances 0.000 description 6
- 238000011160 research Methods 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 230000004438 eyesight Effects 0.000 description 5
- 150000004676 glycans Chemical class 0.000 description 5
- 229920001282 polysaccharide Polymers 0.000 description 5
- 239000005017 polysaccharide Substances 0.000 description 5
- 235000010208 anthocyanin Nutrition 0.000 description 4
- 229930002877 anthocyanin Natural products 0.000 description 4
- 239000004410 anthocyanin Substances 0.000 description 4
- 150000004636 anthocyanins Chemical class 0.000 description 4
- 206010016256 fatigue Diseases 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 244000241838 Lycium barbarum Species 0.000 description 3
- 235000015459 Lycium barbarum Nutrition 0.000 description 3
- 235000021028 berry Nutrition 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 229930003935 flavonoid Natural products 0.000 description 3
- 150000002215 flavonoids Chemical class 0.000 description 3
- 235000017173 flavonoids Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 235000013402 health food Nutrition 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 150000008442 polyphenolic compounds Chemical class 0.000 description 3
- 235000013824 polyphenols Nutrition 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 101001018064 Homo sapiens Lysosomal-trafficking regulator Proteins 0.000 description 2
- 102100033472 Lysosomal-trafficking regulator Human genes 0.000 description 2
- 244000038561 Modiola caroliniana Species 0.000 description 2
- 235000010703 Modiola caroliniana Nutrition 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 229930003944 flavone Natural products 0.000 description 2
- 150000002213 flavones Chemical class 0.000 description 2
- 235000011949 flavones Nutrition 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000000050 nutritive effect Effects 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 201000001275 rectum cancer Diseases 0.000 description 2
- 230000002000 scavenging effect Effects 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 1
- 206010007026 Calculus urethral Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 1
- 206010018276 Gingival bleeding Diseases 0.000 description 1
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010021143 Hypoxia Diseases 0.000 description 1
- GQODBWLKUWYOFX-UHFFFAOYSA-N Isorhamnetin Natural products C1=C(O)C(C)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 GQODBWLKUWYOFX-UHFFFAOYSA-N 0.000 description 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 description 1
- LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 241001106041 Lycium Species 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- 102000004330 Rhodopsin Human genes 0.000 description 1
- 108090000820 Rhodopsin Proteins 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 1
- 235000008758 anthocyanidins Nutrition 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000002929 anti-fatigue Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 238000009412 basement excavation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 235000019784 crude fat Nutrition 0.000 description 1
- -1 cyanidenon Chemical compound 0.000 description 1
- 229960003067 cystine Drugs 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 210000004195 gingiva Anatomy 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 230000007954 hypoxia Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- 235000008800 isorhamnetin Nutrition 0.000 description 1
- IZQSVPBOUDKVDZ-UHFFFAOYSA-N isorhamnetin Chemical compound C1=C(O)C(OC)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 IZQSVPBOUDKVDZ-UHFFFAOYSA-N 0.000 description 1
- 235000008777 kaempferol Nutrition 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229920002414 procyanidin Polymers 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 235000005493 rutin Nutrition 0.000 description 1
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 1
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 description 1
- 229960004555 rutoside Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000015961 tonic Nutrition 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 229960000716 tonics Drugs 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 201000009160 urethral calculus Diseases 0.000 description 1
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention relates to health-care lycium ruthenicum tablets capable of alleviating asthenopia. A preparation method of a lycium ruthenicum extract is optimized and screened, so that an extract which is rich in components with the efficacy of alleviating the asthenopia is obtained; besides, a recipe is optimized and screened, so that the optimal formula of the health-care tablets is determined; banana essence is used for concealing the disagreeable taste of other components, so that the health-care tablets are easy to accept by consumers. The health-care lycium ruthenicum tablets are simple in preparation technology and easy to operate; realization of industrialized production and processing is facilitated; health-care foods are prepared in the form of tablets, so that the health-care lycium ruthenicum tablets are convenient to carry and use, and the asthenopia can be effectively alleviated.
Description
Technical field
The present invention relates to field of health care food, be specifically related to the asthenopic black fruit lyceum health-care tablet of a kind of alleviation.
Background technology
Black fruit lyceum (LyciumruthenicumMurr.), fruit black, another name is " Soviet Union matrimony vine ", Tibetan medicine claims " other agate ", anaesthetic claims " Qiao Nuoying-Ha Er mug(unit of measure) ", for Solanaceae Lycium, many quils, multi-branched, branch is hard in white or canescence, the irregular vertical stripe of tool, sprig top becomes echinate, and 2 ~ 6 pieces, leaf clusters on brachyplast, spends 1 ~ 2 to be born on brachyplast, berry is spherical, in atropurpureus (including mauve pigment) after ripe, slightly cave in top, diameter 4mm ~ 9mm; Highly general at 20cm ~ 50cm, flowering fruit bearing stage is in 5 ~ October; Seed is kidney shape, brown.Perennial salt tolerant, the drought resisting wild barbarum resource of new excavation in recent years, be distributed in Ningxia, Gansu, Qinghai, the Inner Mongol, Xinjiang, Tibet and North Shaanxi loess plateau, also there is distribution in the areas such as the Central Asia, Caucasia and Europe, its ripe berry is black, be rich in anthocyanin class pigment, be different from matrimony vine, therefore locality is referred to as black fruit lyceum, among the people often eaten raw as wild fruit or squeezed the juice do red drink and eat, also in its fruit useful, contained pigment makes dyeing.
Effective medicinal components and the lycium barbarum of black fruit lyceum are close.Modern study finds that lycium ruthenicum fruit is containing a certain amount of essential fatty acid, alkaloid, phenols, protein, vitamin, and containing 18 kinds of essential amino acids, its trace element is also very abundant, in addition containing more reduction polysaccharide and colors, especially containing abundant natural procyanidins, the title of the king that custom has " OPC ".Black fruit lyceum has higher medical value and nutritive value as can be seen here, research finds, its active ingredient mainly comprises the following aspects: (1) nutritional labeling: the crude fat of black fruit lyceum is about 6%, and main fatty acid has 3 kinds, mostly is unrighted acid; Black fruit lyceum contains 17 seed amino acids, and wherein content of glutamic acid is the highest, is secondly asparatate, methionine and cystine minimum.Protein content is about about 11%, and total reducing sugar is about 34%, and content of reducing sugar is about 33%, in addition, has also been rich in multivitamin E etc.; (2) polyphenols such as anthocyanin; (3) Flavonoid substances: be rich in Flavonoid substances in lycium ruthenicum fruit and leaf, Flavonoid substances in fruit is mainly anthocyanin, but the flavones in leaf is different from the flavones in fruit, consists predominantly of rutin, Quercetin, cyanidenon, Isorhamnetin and Kaempferol; (4) OPC.
About the pharmacological action of black fruit lyceum, " brilliant pearl draft ", the Four-Volume Medical Code are recorded, and Tibetan medicine is used as medicine with its ripening fruits, the illnesss such as treatment cardiopyretic disease, heart disease, irregular menstruation, menelipsis." Uygur medicine will " is recorded, the diseases such as lycium ruthenicum fruit and the treatment of root micromicro urethral calculus, tinea scabies, gingiva bleeding gingival hemorrhage, among the people then as strengthening by means of tonics, improving eyesight and depressor.Modern study finds, its pharmacologically active relates generally to the following aspects: (1) is hypoglycemic, antifatigue, the effect of raising immunity of organisms: polysaccharide has good regulating action and is confirmed by a large amount of research institute, and also there is the multiple physiologically active such as raising hypoxia-bearing capability, enhancing immunity, much research shows, black fruit lyceum and lycium ruthenicum polysaccharide have a lot of immunoloregulation function, comprise the activation of various immunocyte, traditional Chinese medical science current research shows, and lycium ruthenicum polysaccharide can strengthen cell and get involved immunity and humoral immune reaction; (2) anti-oxidant anti-aging effect: the ripe berry of black fruit lyceum is rich in abundant pigment polyphenol substance, mauve pigment and OPC etc., the test of many research workers all demonstrates anthocyanin and has scavenging free radicals and oxidation resistant function, OPC has anti-oxidant, scavenging free radicals, and its oxidation resistance is 50 times of vitamin E; (3) anticancer antitumor action: research finds that lycium ruthenicum polysaccharide and pigment polyphenol also have certain prevention and resistant function to tumour and cancer, found by clinical and experimental study, OPC can prevent the carcinoma of the rectum, and preventative higher than colon cancer to the carcinoma of the rectum.
In prior art, black fruit lyceum is usually used in preparing health food, but, not yet have about utilizing black fruit lyceum to prepare the report alleviating asthenopic health food.Anthocyanidin in black fruit lyceum can promote the regrowth of visual purple in retina cell, and Long-Time Service can have the effect of obvious vision protection, has good health-care effect for visual fatigue.Thus, how to make full use of the nutritive value of black fruit lyceum, exploitation has the health-care tablet alleviating kopiopia effect, meets and enriches the growing material requisite of people, significant.
Summary of the invention
The object of the invention is to overcome above-mentioned defect, provide a kind of new black fruit lyceum health-care tablet, it for main active, has excellent alleviation kopiopia effect with black fruit lyceum extract.
The technical scheme that the present invention solves this technical problem is:
The asthenopic black fruit lyceum health-care tablet of a kind of alleviation, it is characterized in that, raw materials by weight is composed as follows:
Black fruit lyceum extract 10 ~ 20
Amylum pregelatinisatum 15 ~ 20
Gelatin 10 ~ 20
PVP 5 ~ 10
Polyethylene glycol 10 ~ 20
Sodium alginate 2 ~ 5
Magnesium laurylsulfate 1 ~ 2
Sodium Benzoate 0.1 ~ 0.2
Flavoring banana essence is appropriate
Surplus is purified water.
Preferably, raw materials by weight is composed as follows:
Black fruit lyceum extract 20
Amylum pregelatinisatum 15
Gelatin 15
PVP 10
Polyethylene glycol 15
Sodium alginate 5
Magnesium laurylsulfate 1
Sodium Benzoate 0.2
Flavoring banana essence is appropriate
Surplus is purified water.
Wherein, the preparation method of described black fruit lyceum extract is: black fruit lyceum is dry, pulverize, cross 120 mesh sieves, to add after petroleum ether degreasing with 85% ethanol by solid-liquid ratio 1:(10 ~ 20) in 40 DEG C of extraction 1 ~ 2h, repeat extraction three times, merging filtrate, obtains thick paste in 90 DEG C of rotary evaporations, dry, pulverize, to obtain final product.
Preferably, the solid-liquid ratio of described 85% ethanol is preferably 1:15 and extracts 2h in 40 DEG C.
Invention also provides the preparation method of the asthenopic black fruit lyceum health-care tablet of above-mentioned alleviation, its operating procedure is: first by black fruit lyceum extract, amylum pregelatinisatum, gelatin and PVP mix, cross 80 mesh sieves, add sodium alginate, polyethylene glycol, flavoring banana essence, Sodium Benzoate and water, softwood processed, cross 18 mesh sieves, dry, whole grain, add magnesium laurylsulfate, mix rear compressing tablet and get final product.
Beneficial effect of the present invention:
(1) the present invention is by being optimized screening to the preparation method of black fruit lyceum extract, obtain the extract being rich in and alleviating kopiopia functional component, effectively can alleviate eye strain, simultaneously, the optimum formula of health-care tablet is determined by formulation optimization screening, its preparation method technique is simple, is easy to operation, is conducive to realizing industrialized production and processing.
(2) the present invention adopts the form of tablet to prepare health food, be convenient for carrying, easy-to-use, serve and alleviate kopiopia effect preferably, use flavoring banana essence to mask the disagreeable taste of other components simultaneously, thus make health-care tablet be easy to allow consumer accept.
Detailed description of the invention
Below in conjunction with specific embodiment, set forth the present invention further.Should be understood that these embodiments are only not used in for illustration of the present invention to limit the scope of the invention.The experimental technique of unreceipted actual conditions in the following example, the usually conveniently conditioned disjunction condition of advising according to manufacturer.Unless otherwise indicated, otherwise all percentage, ratio, ratio or number by weight.
Unless otherwise defined, all specialties used in literary composition and scientific words and one skilled in the art the meaning be familiar with identical.In addition, any method similar or impartial to described content and material all can be applicable in the inventive method.The use that better implementation method described in literary composition and material only present a demonstration.
Embodiment 1:
Black fruit lyceum is dry, pulverize, cross 120 mesh sieves, extract 2h by solid-liquid ratio 1:10 in 40 DEG C with 85% ethanol after adding petroleum ether degreasing, repeat extraction three times, merging filtrate, obtain thick paste in 90 DEG C of rotary evaporations, dry, pulverize, obtain black fruit lyceum extract, take each raw material as following weight percent:
Black fruit lyceum extract 10
Amylum pregelatinisatum 20
Gelatin 18
PVP 8
Polyethylene glycol 10
Sodium alginate 2
Magnesium laurylsulfate 2
Sodium Benzoate 0.1
Flavoring banana essence is appropriate
Surplus is purified water;
First by black fruit lyceum extract, amylum pregelatinisatum, gelatin and PVP mix, and cross 80 mesh sieves, add sodium alginate, polyethylene glycol, flavoring banana essence, Sodium Benzoate and water, softwood processed, cross 18 mesh sieves, drying, whole grain, adds magnesium laurylsulfate, mixes rear compressing tablet and get final product.
Embodiment 2:
Black fruit lyceum is dry, pulverize, cross 120 mesh sieves, extract 2h by solid-liquid ratio 1:15 in 40 DEG C with 85% ethanol after adding petroleum ether degreasing, repeat extraction three times, merging filtrate, obtain thick paste in 90 DEG C of rotary evaporations, dry, pulverize, obtain black fruit lyceum extract, take each raw material as following weight percent:
Black fruit lyceum extract 20
Amylum pregelatinisatum 15
Gelatin 15
PVP 10
Polyethylene glycol 15
Sodium alginate 5
Magnesium laurylsulfate 1
Sodium Benzoate 0.2
Flavoring banana essence is appropriate
Surplus is purified water;
First by black fruit lyceum extract, amylum pregelatinisatum, gelatin and PVP mix, and cross 80 mesh sieves, add sodium alginate, polyethylene glycol, flavoring banana essence, Sodium Benzoate and water, softwood processed, cross 18 mesh sieves, drying, whole grain, adds magnesium laurylsulfate, mixes rear compressing tablet and get final product.
Embodiment 3:
Black fruit lyceum is dry, pulverize, cross 120 mesh sieves, extract 1h by solid-liquid ratio 1:20 in 40 DEG C with 85% ethanol after adding petroleum ether degreasing, repeat extraction three times, merging filtrate, obtain thick paste in 90 DEG C of rotary evaporations, dry, pulverize, obtain black fruit lyceum extract, take each raw material as following weight percent:
Black fruit lyceum extract 15
Amylum pregelatinisatum 18
Gelatin 20
PVP 10
Polyethylene glycol 12
Sodium alginate 5
Magnesium laurylsulfate 2
Sodium Benzoate 0.2
Flavoring banana essence is appropriate
Surplus is purified water;
First by black fruit lyceum extract, amylum pregelatinisatum, gelatin and PVP mix, and cross 80 mesh sieves, add sodium alginate, polyethylene glycol, flavoring banana essence, Sodium Benzoate and water, softwood processed, cross 18 mesh sieves, drying, whole grain, adds magnesium laurylsulfate, mixes rear compressing tablet and get final product.
Embodiment 4: black fruit lyceum alleviates the drug efficacy study of kopiopia health-care tablet
Be selected from A, B two Subject Population:
A group Subject Population: school high school student 50 people, wherein male 25 people, female 25 people, age: 15 ~ 18 years old.Symptom: because learning pressure is comparatively large, cause liver fire exuberance, occur the dry and astringent fatigue of eyes, shed tears, eyesight declines to some extent, fuzzyyer depending on thing.
B group Subject Population: staff in post 50 people, wherein male 25 people, female 25 people, age: 25 ~ 45 years old., there is eyes swelling once in a while, swell and ache, redly redly to shed tears, dizzy headache in symptom: because operating pressure is comparatively large, daily life system is irregular, and every day uses computer for a long time, causes liver fire exuberance, and go out to lose face puckery, fatiguability, and hypopsia is fuzzyyer depending on thing.
A, B two groups of Subject Population take the black fruit lyceum fatigue-relieving health-care tablet of the embodiment of the present invention 2 every day for 3 times, each serving with 4, take with warm water, take one month continuously.
Efficacy assessment standard:
Invalid: symptom is without alleviation or DeGrain.
Effective: the dry and astringent sense of fatigue of eyes, swelling sense disappear to some extent, and eyesight increases before comparatively drinking the present invention, and other symptoms alleviate to some extent
Effective: remission is remarkable, and clear depending on thing, eyesight is recovered to some extent.
Result is as shown in table 1:
Table 1 black fruit lyceum alleviates kopiopia health-care tablet pharmacodynamic results
Result shows, and black fruit lyceum of the present invention is alleviated kopiopia health-care tablet and alleviated eye strain effect brilliance, creates significant technique effect, has broad application prospects.
The foregoing is only preferred embodiment of the present invention, and be not used to limit substantial technological context of the present invention, substantial technological content of the present invention is broadly defined in the right of application, any technology entities that other people complete or method, if with application right define identical, also or a kind of change of equivalence, be all covered by being regarded as among this right.
Claims (5)
1. alleviate an asthenopic black fruit lyceum health-care tablet, it is characterized in that, raw materials by weight is composed as follows:
Black fruit lyceum extract 10 ~ 20
Amylum pregelatinisatum 15 ~ 20
Gelatin 10 ~ 20
PVP 5 ~ 10
Polyethylene glycol 10 ~ 20
Sodium alginate 2 ~ 5
Magnesium laurylsulfate 1 ~ 2
Sodium Benzoate 0.1 ~ 0.2
Flavoring banana essence is appropriate
Surplus is purified water.
2. the asthenopic black fruit lyceum health-care tablet of alleviation according to claim 1, it is characterized in that, raw materials by weight is composed as follows:
Black fruit lyceum extract 20
Amylum pregelatinisatum 15
Gelatin 15
PVP 10
Polyethylene glycol 15
Sodium alginate 5
Magnesium laurylsulfate 1
Sodium Benzoate 0.2
Flavoring banana essence is appropriate
Surplus is purified water.
3. the asthenopic black fruit lyceum health-care tablet of alleviation according to claim 1 and 2, it is characterized in that, the preparation method of described black fruit lyceum extract is: be dry, pulverize by black fruit lyceum, cross 120 mesh sieves, to add after petroleum ether degreasing with 85% ethanol by solid-liquid ratio 1:(10 ~ 20) extract 1 ~ 2h in 40 DEG C, repeat extraction three times, merging filtrate, thick paste is obtained in 90 DEG C of rotary evaporations, dry, pulverize, to obtain final product.
4. the asthenopic black fruit lyceum health-care tablet of alleviation according to claim 3, is characterized in that, the solid-liquid ratio of described 85% ethanol is preferably 1:15 and extracts 2h in 40 DEG C.
5. the preparation method of the asthenopic black fruit lyceum health-care tablet of the alleviation according to any one of claim 1 ~ 4, it is characterized in that, its operating procedure is: first by black fruit lyceum extract, amylum pregelatinisatum, gelatin and PVP mix, and cross 80 mesh sieves, add sodium alginate, polyethylene glycol, flavoring banana essence, Sodium Benzoate and water, softwood processed, crosses 18 mesh sieves, dry, whole grain, adds magnesium laurylsulfate, mixes rear compressing tablet and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510711969.4A CN105231447B (en) | 2015-10-28 | 2015-10-28 | A kind of black fruit fructus lycii health-care tablet for alleviating asthenopia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510711969.4A CN105231447B (en) | 2015-10-28 | 2015-10-28 | A kind of black fruit fructus lycii health-care tablet for alleviating asthenopia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105231447A true CN105231447A (en) | 2016-01-13 |
| CN105231447B CN105231447B (en) | 2018-05-18 |
Family
ID=55029509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510711969.4A Active CN105231447B (en) | 2015-10-28 | 2015-10-28 | A kind of black fruit fructus lycii health-care tablet for alleviating asthenopia |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105231447B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107019218A (en) * | 2017-04-21 | 2017-08-08 | 中国科学院西北高原生物研究所湖州高原生物资源产业化创新中心 | It is a kind of that there is the black fruit fructus lycii prescription and preparation for alleviating visual fatigue |
| CN107080239A (en) * | 2017-04-21 | 2017-08-22 | 中国科学院西北高原生物研究所湖州高原生物资源产业化创新中心 | It is a kind of that there is the black fruit fructus lycii piece and its preparation technology for alleviating visual fatigue |
| CN107997048A (en) * | 2017-11-29 | 2018-05-08 | 中国科学院兰州化学物理研究所 | A kind of composition for having effects that to improve eyesight |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103262998A (en) * | 2013-05-30 | 2013-08-28 | 青海紫阳生物科技有限公司 | Wild lycium ruthenicum tablet and preparation method |
| CN104041821A (en) * | 2014-07-02 | 2014-09-17 | 中国科学院西北高原生物研究所 | Lycium ruthenicum murr anthocyanin chewable tablet |
| CN104383116A (en) * | 2014-12-01 | 2015-03-04 | 宁夏农林科学院 | Lycium ruthenicum tablet |
| CN104544052A (en) * | 2014-12-19 | 2015-04-29 | 苟春虎 | Lycium ruthenicum murr buccal tablet capable of protecting eyesight and improving eyesight |
-
2015
- 2015-10-28 CN CN201510711969.4A patent/CN105231447B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103262998A (en) * | 2013-05-30 | 2013-08-28 | 青海紫阳生物科技有限公司 | Wild lycium ruthenicum tablet and preparation method |
| CN104041821A (en) * | 2014-07-02 | 2014-09-17 | 中国科学院西北高原生物研究所 | Lycium ruthenicum murr anthocyanin chewable tablet |
| CN104383116A (en) * | 2014-12-01 | 2015-03-04 | 宁夏农林科学院 | Lycium ruthenicum tablet |
| CN104544052A (en) * | 2014-12-19 | 2015-04-29 | 苟春虎 | Lycium ruthenicum murr buccal tablet capable of protecting eyesight and improving eyesight |
Non-Patent Citations (1)
| Title |
|---|
| 李进，等: "黑果枸杞色素最优提取工艺条件研究", 《新疆师范大学学报(自然科学版)》 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107019218A (en) * | 2017-04-21 | 2017-08-08 | 中国科学院西北高原生物研究所湖州高原生物资源产业化创新中心 | It is a kind of that there is the black fruit fructus lycii prescription and preparation for alleviating visual fatigue |
| CN107080239A (en) * | 2017-04-21 | 2017-08-22 | 中国科学院西北高原生物研究所湖州高原生物资源产业化创新中心 | It is a kind of that there is the black fruit fructus lycii piece and its preparation technology for alleviating visual fatigue |
| CN107997048A (en) * | 2017-11-29 | 2018-05-08 | 中国科学院兰州化学物理研究所 | A kind of composition for having effects that to improve eyesight |
| CN107997048B (en) * | 2017-11-29 | 2021-03-30 | 中国科学院兰州化学物理研究所 | Composition with eyesight improving effect |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105231447B (en) | 2018-05-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103082265B (en) | Spicy garlic tomato chili sauce and preparation method thereof | |
| CN101023802A (en) | Series products of all-nutrient green health-care bean vermicellic and instant bean vermicellic and preparing method | |
| CN108323719A (en) | A kind of black coarse grain powder with kidney-tonifying and hair-blackening function | |
| Arshad et al. | Functional foods and human health: an overview | |
| CN105211867A (en) | A kind of black fruit lyceum compound fruit ferment and preparation method thereof | |
| CN106072143A (en) | A kind of Lycium ruthenicum Murr. buccal tablet and preparation method thereof | |
| CN105213261A (en) | A kind of black fruit matrimony vine oxidation resistant skin care item | |
| CN109007856A (en) | The meal replacement powder and preparation method that a kind of suitable hypertension, hyperlipidemia, hyperglycemia and people with high uric acid are taken | |
| CN105211864A (en) | A kind of black fruit lyceum mixed fruit ferment and preparation method thereof | |
| CN104855648A (en) | Tartary buckwheat health tea and preparation method thereof | |
| CN105231446A (en) | Composition containing lycium ruthenicum and fruit enzymes and preparation method of composition | |
| CN104432036A (en) | Health care nutrition composition capable of relieving asthenopia as well as preparation method and application thereof | |
| CN107183290A (en) | A kind of lycium ruthenicum pressed candy and preparation method thereof | |
| CN105124347A (en) | Moringa oleifera blood-glucose-reducing composition and preparation method thereof | |
| CN105707637A (en) | Solid beverage capable of reduce blood glucose, and preparation method thereof | |
| CN105231447A (en) | Health-care lycium ruthenicum tablets capable of alleviating asthenopia | |
| CN108308597A (en) | A kind of malnutrition tailored version clinical nutrition formula and preparation method thereof | |
| CN103330175A (en) | Seasoning made of natural plant compositions and preparation method thereof | |
| CN105076999A (en) | Undaria pinnatifida and Chinese herbal medicine compounded nutritional noodles and production method thereof | |
| CN105105123B (en) | A kind of black fruit fructus lycii health-care tablet and preparation method thereof | |
| CN104839522A (en) | Nutrition and health Guiling jelly and preparation method thereof | |
| CN105725064A (en) | Lotus noodle | |
| CN105341704A (en) | Brown sugar red bean paste | |
| CN105211865A (en) | A kind of black fruit lyceum ferment and preparation method thereof | |
| CN109527091A (en) | The meal replacement powder and preparation method that a kind of suitable hyperglycemia, hypertension and people with hyperlipidemia are taken |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: 810000 Xining science and Technology Industrial Park, Qinghai, No. four, No. 26 Applicant after: Qinghai flower Biotechnology Co., Ltd. Address before: 810000 Xining science and Technology Industrial Park, Qinghai, No. four, No. 26 Applicant before: QINGHAI YOUNIKE BIOTECHNOLOGY CO., LTD. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180427 Address after: 810000 Qinghai Xining biological science and Technology Industrial Park, 104 office, four road 26 office building. Applicant after: QINGHAI ZHIYE TECHNOLOGY CONSULTING SERVICE CO., LTD. Address before: 810000 Qinghai Xining biological science and Technology Industrial Park, No. four road 26. Applicant before: Qinghai flower Biotechnology Co., Ltd. |