CN107252116A - A kind of complex health care product of relieving mental strain and helping sleep - Google Patents

A kind of complex health care product of relieving mental strain and helping sleep Download PDF

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Publication number
CN107252116A
CN107252116A CN201710481063.7A CN201710481063A CN107252116A CN 107252116 A CN107252116 A CN 107252116A CN 201710481063 A CN201710481063 A CN 201710481063A CN 107252116 A CN107252116 A CN 107252116A
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health care
care product
oil
complex health
parts
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黄�俊
陈旭
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Profit Line (beijing) Biological Technology Co Ltd
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Profit Line (beijing) Biological Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C11B1/04—Pretreatment of vegetable raw material
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C11B1/104—Production of fats or fatty oils from raw materials by extracting using super critical gases or vapours
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/001—Refining fats or fatty oils by a combination of two or more of the means hereafter
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides a kind of complex health care product of relieving mental strain and helping sleep.A kind of complex health care product of relieving mental strain and helping sleep, is mainly made up of following component：By weight, 200 500 parts of walnut oil, 100 300 parts of spine date seed oil, 40 100 parts of Boxthorn Seed Oil, 20 70 parts of ganoderma lucidum spore oil, 0 20 parts of vitamin e1.The coordinated that the complex health care product of the present invention passes through various materials, start with from multiple dimensions such as blood, blood vessel, activating immune system, elimination superoxide radical, the oxygen-enriched ability of offer, immune bidirectional modulation, calmness, liver protecting and kidney invigoratings, comprehensive the eliminate the effects of the act physiology of sleep quality and the undesirable element of psychological aspects, improve sleep quality, play significant relieving mental strain and helping sleep effect.

Description

A kind of complex health care product of relieving mental strain and helping sleep
Technical field
The present invention relates to health product technology field, more particularly, to a kind of complex health care product of relieving mental strain and helping sleep.
Background technology
Insomnia refers to that patient is unsatisfactory on the length of one's sleep or quality and influences a kind of subjective experience of social function in the daytime.It is existing There is limitation to the understanding of insomnia in clinical medicine science, generally lack the clear and definite cause of disease, or excluding possible cause insomnia Insomnia is still left after the cause of disease, mainly including Psychophysiological insomnia, idiopathic insomnia, subjective insomnia and part physiology Property disease caused by have a sleepless night.Research is it is also shown that insomnia caused by physiological disorder is closely related with hypoimmunity.But no matter Any insomnia, is required for very long therapeutic process, and easily recurs, and therefore, early stage active prevention is extremely important.With existing For the quickening of social rhythm, people pay attention to sleep-assistant health care further, but still are limited to simple dietotherapy at present, have little effect.Therefore, It is that this area is urgently to be resolved hurrily to improve the quality of life of people there is provided the health products of the more preferable relieving mental strain and helping sleep of new, effect A technical problem.
In view of this, it is special to propose the present invention.
The content of the invention
It is an object of the invention to provide a kind of complex health care product of relieving mental strain and helping sleep, described complex health care product utilizes science Compatibility relationship, with more significant relieving mental strain and helping sleep and improve immunity effect, and it is natural to draw materials, without any toxicity and side effects.
In order to realize the above object the invention provides following technical scheme：
A kind of complex health care product of relieving mental strain and helping sleep, is mainly made up of following component：By weight,
Wherein, walnut oil contains abundant squalene, Flavonoid substances and polyphenolic substance.Squalene can promote blood to follow Ring, activates physical function cell, anti-inflammation and sterilization, repair cell；Flavonoid substances and polyphenolic substance can strengthen the expansion of blood vessel Ability, regulation blood fat, reduction cholesterol and blood glucose, improves blood vessel microcirculation, protects cell not by radical damage, improves comprehensively Immunity.Walnut oil also has regulation body's cholesterol, cerebrum tonifying, promotes retinal development and promote bone growth, improve sleep.Separately Nutritional ingredient in outer walnut oil, have effects that to invigorate the kidney and stop nocturnal emission, the diuresis that helps digestion, warm lung Dingchuan.
Spine date seed oil contains various trace elements, vitamin C and the plants such as 17 kinds of amino acid, potassium, calcium, sodium, zinc, iron, copper, manganese Thing sterol etc..Its active ingredient promotes liver cell regeneration and protects liver cell, antifatigue, improves immune function of human body, promotes blood Liquid cyclic activation physical function cell, can be effectively improved neurasthenia, calmness, improve sleep, brain healthy prevention senile dementia Disease.
Boxthorn Seed Oil contains abundant and comprehensive bioactive substance and oleic acid, linoleic acid, gamma linoleic acid, β carrots Element, SOD etc..Boxthorn Seed Oil has obvious effect to regulation blood fat, liver-nourishing and eyesight-improving, kidney tonifying anticancer.
The triterpenes ganoderic acid that ganoderma lucidum spore oil contains has strong pharmacological activity, has protect liver, removing toxic substances, kills cancer cell And pain-relieving functions.Unrighted acid that ganoderma lucidum spore oil contains can pre- preventing thrombosis and artery sclerosis, reduce malignant cholesterol, net Change blood and eliminate free radical.The organic germanium that ganoderma lucidum spore oil contains has decompression, diuresis, analgesic effect, induces and promotes huge The phagocytosis of phagocyte.Ganoderma lucidum spore oil suppresses the propagation of tumour cell by activated NK, and can be with bidirectional modulation The immune system of human body.
Vitamin E is that life continues one of required nutrient.It can promote sex hormone to secrete, and improve fecundity, protect T lymphocytes, protection red blood cell, Green Tea Extract oxidation are protected, the lipid peroxidation reaction in ocular lens body can be suppressed, make peripheral blood Enlargement of pipe, improves blood circulation.
The present invention five kinds of compositions from more than, the proportioning composition complex health care product through science, on the basis of strengthen immunity On, it can not only reach not introduce in relieving mental strain and helping sleep effect more significant than existing health products, and the formula of the present invention and appoint The medicinal material or auxiliary material of what toxic side effect, therefore be used for a long time safer.
There is the effect of stronger improvement blood microcirculation and activation body function cell in the present invention, in walnut oil, and And improve sleep with spine date seed oil collocation, prevent senile dementia；Boxthorn Seed Oil is except that can remove the rubbish in blood, moreover it is possible to subtract Few vascular wall cholesterol deposition, prevents the SOD contained in blood fat atherosclerosis, Boxthorn Seed Oil, is assisted together with vitamin E Make, the effect with very strong elimination superoxide radical, while cooperateing with the effect for playing liver protecting and kidney invigorating with spine date seed oil；With coker Peach oil, Boxthorn Seed Oil and spine date seed oil three's synergic adjustment blood fat thrombus；Active component in ganoderma lucidum spore oil can be with two-way tune The immune system of human body is saved, it cooperates with Green Tea Extract to aoxidize with vitamin E.It can be seen that, in the Halth-care composition that the present invention is provided, The emphasis of each component is different, but by the coordinated of various materials, from blood, blood vessel, activating immune system, elimination Multiple dimensions such as superoxide radical, the oxygen-enriched ability of offer, immune bidirectional modulation, calmness, liver protecting and kidney invigorating are started with, and are eliminated the effects of the act comprehensively The physiology of sleep quality and the undesirable element of psychological aspects, improve sleep quality, play significant relieving mental strain and helping sleep effect.
Formula can also further optimize above, to obtain more preferable relieving mental strain and helping sleep effect, and for example formula is：By weight Meter,
Oily composition has a major impact to the health-care effect of formula in all formulas described above, in order to improve health care effect The oil of fruit preferably following quality：
Preferably, the walnut oil contains following component：Weight percentage,
Unrighted acid >=93%, leukotrienes Ω 3 >=15% and leukotrienes Ω 6 >=56%.
The unrighted acid includes leukotrienes Ω 3 and leukotrienes Ω 6；The accountings of leukotrienes Ω 3 refer to leukotrienes Ω 3 The proportion of walnut oil is accounted for, the accountings of leukotrienes Ω 6 refer to the proportion that leukotrienes Ω 6 accounts for walnut oil.
The oil of the quality can be through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the supercritical extract The temperature that method is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, walnut oil is after ultramicro grinding, and the particle diameter of walnut kernel powder is less than 100 μm, and powder diameter is uniform, carefully Cell wall is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2The temperature that supercritical extraction is used For normal temperature, walnut is in CO2Atmosphere in, should under the conditions of can ensure that the active component in walnut is particularly thermally sensitive work Property material and oxidizable active material do not degraded by high-temperature oxygen, and the recovery rate of active component is high, obtained core Peach oil quality is good.
Preferably, the spine date seed oil contains following component：Weight percentage,
Total saposins >=0.42 ‰, oleic acid >=49%, linoleic acid >=26% and vitamin E >=0.27 ‰.
The oil of the quality can be through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the supercritical extract The temperature that method is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, spina date seed is after ultramicro grinding, and the particle diameter of Spine Date Seed is less than 100 μm, and powder diameter is uniform, carefully Cell wall is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2The temperature that supercritical extraction is used For normal temperature, spina date seed is in CO2Atmosphere in, should under the conditions of can ensure that the active component in spina date seed is particularly temperature sensitive Active material and oxidizable active material do not degraded by high-temperature oxygen, and the recovery rate of active component is high, obtains Spine date seed oil quality better.
There is low recovery rate, dissolvent residual, active component in squeezing, the organic solvent extraction of routine, and CO of the present invention2Supercritical extraction process completely avoid problem above.
Preferably, the Boxthorn Seed Oil includes following component：Weight percentage, linoleic acid >=61.5%, α-Asia Numb acid >=3.1%, gamma-Linolenic acid >=3.0%, vitamin E >=0.452% and selenium >=0.44/100000.
The Boxthorn Seed Oil of the quality can be through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, described super to face The temperature that boundary's extraction is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, matrimony vine seed is after ultramicro grinding, and the particle diameter at matrimony vine seed powder end is less than 100 μm, and powder diameter is uniform, carefully Cell wall is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2The temperature that supercritical extraction is used For normal temperature, matrimony vine seed is in CO2Atmosphere in, should under the conditions of can ensure that the active component in matrimony vine seed is particularly temperature sensitive Active material and oxidizable active material do not degraded by high-temperature oxygen, and the recovery rate of active component is high, obtains Boxthorn Seed Oil quality better.There is low recovery rate, dissolvent residual, active component destructible in squeezing, the organic solvent extraction of routine The problems such as, and CO of the present invention2Supercritical extraction process completely avoid problem above.
Preferably, the ganoderma lucidum spore oil includes following component：Triterpenes aliphatic acid, unrighted acid, organic germanium and GL-B.
The ganoderma lucidum spore oil of the quality is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, described super to face The temperature that boundary's extraction is used is 20-40MPa for 25-35 DEG C, pressure.
In the present invention, Reishi sporule is after ultramicro grinding, and the particle diameter of Reishi sporule powder is less than 100 μm, and powder diameter is equal Even, cell membrane is broken, surface area and porosity increase, afterwards by CO2Supercritical extract, CO2What supercritical extraction was used Temperature is normal temperature, and Reishi sporule is in CO2Atmosphere in, should under the conditions of can ensure in Reishi sporule active component be particularly pair Temperature sensitive active material and oxidizable active material are not degraded by high-temperature oxygen, and the recovery rate of active component Height, obtained ganoderma lucidum spore oil quality better.
There is low recovery rate, dissolvent residual, active component in squeezing, the organic solvent extraction of routine, and CO of the present invention2Supercritical extraction process completely avoid problem above.
Above, degumming, depickling for example can add alkali depickling (to determine alkali number, plus alkali with crude oil acid value using conventional means Need to stir 10 minutes with 90rpm speed afterwards), heating is needed in deacidification, and heating rate preferably is 1 DEG C/min.
For formulation, although the present invention can be made into the formulations such as tablet, pill, paste or capsule in theory, but be due to The main component of the present invention is oils, therefore, is advisable with soft capsule, its absorptivity and stability are higher.
The capsule shells that soft capsule of the prior art is used are generally the formula containing pigment, but pigment is in the presence of more or less Side effect, therefore, the invention provides following capsule shells formula：By weight,
200-500 parts of gelatin,
150-300 parts of glycerine,
250-500 parts of purified water.
Compared with prior art, capsule shells of the invention formula is simpler, safe., can if considering lucifuge demand certainly To solve by other means, for example, change the color of outer packing, so both met lucifuge needs, and turn avoid introducing pigment Deng hypotoxicity raw material.As example, if any other side demand, then as far as possible not to edible part addition exogenous material, and It is improved on packing.
In the formula of above-mentioned capsule shells, the content of each composition can also be improved further, to improve stability, for example：
Gelatin is preferred 400-500 parts, and glycerine is preferred 150-200 parts, and purified water is preferred 400-500 parts.
The capsule shells can use following preparation method：First glycerine, purified water are mixed, gained mixture after gelatin is added Stirred 1-2 hours at 65-75 DEG C, then stand 2-3 hours, cast molding afterwards obtains rubber, is molded using capsule machine pelleting.
To sum up, compared with prior art, the present invention achieves following technique effect：
(1) by walnut oil, spine date seed oil, Boxthorn Seed Oil, five kinds of composition scientific compatibilities of ganoderma lucidum spore oil and vitamin E, reach To significant relieving mental strain and helping sleep and raising immunity effect；
(2) pigment conventional in capsule shells is removed, the security of health products is improved；
(3) by improving CO2The operating condition of supercritical extraction process, is improved to walnut oil, spine date seed oil, matrimony vine seed The extraction yield of oil and ganoderma lucidum spore oil, and avoid a series of problems introduced caused by the material such as organic solvent and (for example go Except solvent cost, blowdown flow rate, dissolvent residual etc.), especially effectively prevent the oxidation and loss of heat-sensitive materials, resulting product Advantage in terms of curative effect and stability is more prominent.
Embodiment
Technical scheme is clearly and completely described below in conjunction with embodiment, but ability Field technique personnel will be understood that following described embodiment is a part of embodiment of the invention, rather than whole embodiments, The present invention is merely to illustrate, and is not construed as limiting the scope of the present invention.Based on the embodiment in the present invention, the common skill in this area The every other embodiment that art personnel are obtained under the premise of creative work is not made, belongs to the model that the present invention is protected Enclose.Unreceipted actual conditions person in embodiment, the condition advised according to normal condition or manufacturer is carried out.Agents useful for same or instrument Unreceipted production firm person, is the conventional products that can be obtained by commercially available purchase.
Embodiment 1
Walnut oil is extracted from walnut kernel：
1st, pre-process：Walnut kernel is cleaned, dust and other impurity is screened out.
2、CO2Supercritical extract：Temperature be 25 DEG C, pressure be to extract once under conditions of 30MPa or so, collect respectively Oil and the dregs of fat.
3rd, degumming, depickling：Plus alkali depickling, determine to need after alkali number, plus alkali with crude oil acid value to stir 10 with 90rpm speed Minute, heated in deacidification with 1 DEG C/min heating rates.
As a result：
Gained walnut oil contains following component：Weight percentage,
Unrighted acid is that 93.5%, leukotrienes Ω 3 is 15% and leukotrienes Ω 6 is 56.5%；The unsaturated lipid Fat acid includes leukotrienes Ω 3 and leukotrienes Ω 6.
Embodiment 2
Walnut oil is extracted from walnut kernel：
1st, pre-process：Walnut is cleaned, dust and other impurity is screened out.
2、CO2Supercritical extract：Be in temperature, 35 DEG C, pressure be 20MPa under conditions of extract once, respectively collect oil And the dregs of fat.
3rd, degumming, depickling：Plus alkali depickling, determine to need after alkali number, plus alkali with crude oil acid value to stir 10 with 90rpm speed Minute, heated in deacidification with 1 DEG C/min heating rates.
Gained walnut oil contains following component：Weight percentage,
Unrighted acid is that 93%, leukotrienes Ω 3 is 15.1% and leukotrienes Ω 6 is 56%；
Embodiment 3
Ganoderma lucidum spore oil is extracted from Reishi sporule：
Step and condition be the same as Example 1.
The composition of detection gained ganoderma lucidum spore oil is more containing triterpenes aliphatic acid, unrighted acid, organic germanium and ganoderma lucidum Sugar.
Embodiment 4
Prepare spine date seed oil：
Step and condition be the same as Example 1.
Gained spine date seed oil contains following component：By weight,
Total saposins 0.42 ‰, oleic acid 49%, linoleic acid 26% and vitamin E 0.27 ‰.
Embodiment 5
Prepare Boxthorn Seed Oil：
Step and condition be the same as Example 1.
The component content of detection gained Boxthorn Seed Oil, it is as a result as follows：
By weight percentage, linoleic acid 61.5%, alpha-linolenic acid 3.1%, gamma-Linolenic acid 3.0%, vitamin E0.452% and selenium 0.44/100000.
Embodiment 6
Prepare capsule shells：
1st, feeding：Gelatin 400g, glycerine 200g, purified water 250g.
2nd, prepare：First glycerine, purified water are mixed, gained mixture after gelatin is added and is stirred 2 hours at 65 DEG C, then it is quiet Put 2 hours, cast molding afterwards obtains rubber, be molded using capsule machine pelleting.
Embodiment 7
From embodiment 6 to differ only in formula different, be：Gelatin 500g, glycerine 150g, purified water 500g.
Embodiment 8
From embodiment 6 to differ only in formula different, be：Gelatin 400g, glycerine 200g, purified water 300g.
Embodiment 9
Prepare complex health care product：
1st, draw materials：Walnut oil 400g, spine date seed oil 150g, Boxthorn Seed Oil 70g, ganoderma lucidum spore oil 50g, vitamin e1 0g.
2nd, capsule is prepared：All raw materials in 1st step are mixed, homogeneous, in the capsule shells that the offer of embodiment 8 is provided.
Embodiment 10
It is different from the proportioning for differing only in primary raw material of embodiment 9, i.e. walnut oil, spine date seed oil, Boxthorn Seed Oil, spirit The proportioning of Ganoderma lucidum spore oil and vitamin E, be：Walnut oil 500g, spine date seed oil 100g, Boxthorn Seed Oil 100g, ganoderma lucidum spore oil 20g, vitamin E2 0g.
Embodiment 11
It is different from the proportioning for differing only in primary raw material of embodiment 9, i.e. walnut oil, spine date seed oil, Boxthorn Seed Oil, spirit The proportioning of Ganoderma lucidum spore oil and vitamin E, be：Walnut oil 200g, spine date seed oil 300g, Boxthorn Seed Oil 40g, ganoderma lucidum spore oil 70g, Vitamin e1 0g.
Comparative example 1
It is different from the proportioning for differing only in primary raw material of embodiment 9, i.e. walnut oil, spine date seed oil, Boxthorn Seed Oil, spirit The proportioning of Ganoderma lucidum spore oil and vitamin E, be：Walnut oil 180g, spine date seed oil 310g, Boxthorn Seed Oil 110g, ganoderma lucidum spore oil 80g, vitamin e1 0g.
Comparative example 2
Comparative example 2 is commercially available walnut oil and Boxthorn Seed Oil in mass ratio 40:7 are made into, and manufacturing process is with comparative example 1.
Comparative example 3
Comparative example 3 is commercially available Boxthorn Seed Oil and commercially available spine date seed oil in mass ratio 7:15 are made into, the same comparative example of manufacturing process 1。
Comparative example 4
Comparative example 4 is commercially available walnut oil and commercially available ganoderma lucidum spore oil in mass ratio 8:1 is made into, and manufacturing process is with comparative example 1.
Comparative example 5
Comparative example 5 is commercially available walnut oil, Boxthorn Seed Oil and commercially available spine date seed oil in mass ratio 40:7:15 are made into, system Make process with comparative example 1.
Comparative example 6
Comparative example 6 is commercially available walnut oil, Boxthorn Seed Oil, commercially available spine date seed oil and vitamin E in mass ratio 40:7: 15:1 is made into, and manufacturing process is with comparative example 1.
Comparative example 7
It is different from the extraction conditions for differing only in spine date seed oil of embodiment 9, with reference to patent application CN1279894A's Embodiment 1.
The global natural perfume material Co., Ltd in commercially available walnut oil producer Jiangxi used in the comparative example of the present invention, commercially available Chinese holly Qi Ziyou producers pray for blessings in Ningxia medlar biological Science and Technology Ltd., and commercially available ganoderma lucidum spore oil producer Guangzhou Jingjing biotechnology is limited Company, the commercially available happy Chemical Co., Ltd.s of spine date seed oil producer Jin Jin.
Experimental example
1st, extension yellow Jackets length of one's sleep experiment
Principle：On the basis of carbrital hypnosis, whether observation tested material can extend the length of one's sleep, if the length of one's sleep Extension, then illustrate that tested material and carbrital have synergy.
First carry out preliminary experiment before doing formal experiment, it is determined that make animal 100% fall asleep, but do not make the length of one's sleep it is long penta Barbital sodium dosage (40mg/kg).Animal is given after physiological saline and health products given the test agent successively, 10- before peak effect occurs 15 minutes, yellow Jackets 50mg/kg is injected intraperitoneally to each group animal, using righting reflex loss as index, given the test agent is observed Whether the yellow Jackets length of one's sleep can be extended.
Given the test agent includes embodiment 9 to 11 and comparative example 1 to 7.
As a result show, embodiment 9 to 11 can extend the yellow Jackets length of one's sleep, and with statistical significance.Wherein The best results of embodiment 9, while comparative example 1 to 7 is not obviously prolonged the yellow Jackets length of one's sleep.Each health products are to penta bar Than the appropriate influence for receiving the inducing mouse length of one's sleep as shown in table 1 (dosage is 40mg/kg).
Table 1
Compared with control group：**P<0.0.1。
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent The present invention is described in detail with reference to foregoing embodiments for pipe, it will be understood by those within the art that：Its according to The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered Row equivalent substitution；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology The scope of scheme.

Claims (10)

1. a kind of complex health care product of relieving mental strain and helping sleep, it is characterised in that be mainly made up of following component：By weight,
2. complex health care product according to claim 1, it is characterised in that by weight,
3. complex health care product according to claim 1, it is characterised in that the walnut oil contains following component：By weight Percentage composition meter,
Unrighted acid >=93%, leukotrienes Ω 3 >=15% and leukotrienes Ω 6 >=56%；The unrighted acid includes Leukotrienes Ω 3 and leukotrienes Ω 6；
Preferably, the walnut oil is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the supercritical extract The temperature that method is used is 20-40MPa for 25-35 DEG C, pressure.
4. complex health care product according to claim 1, it is characterised in that the spine date seed oil contains following component：By weight Percentage composition meter is measured,
Total saposins >=0.42 ‰, oleic acid >=49%, linoleic acid >=26% and vitamin E >=0.27 ‰；
Preferably, the spine date seed oil is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the overcritical extraction It is 20-40MPa for 25-35 DEG C, pressure to follow the example of the temperature used.
5. complex health care product according to claim 1, it is characterised in that the Boxthorn Seed Oil includes following component：By weight Percentage composition meter is measured,
Linoleic acid >=61.5%, alpha-linolenic acid >=3.1%, gamma-Linolenic acid >=3.0%, vitamin E >=0.452% and selenium >= 0.44/100000；
Preferably, the Boxthorn Seed Oil is through ultramicro grinding, CO2Supercritical extract, degumming, depickling are prepared from, the overcritical extraction It is 20-40MPa for 25-35 DEG C, pressure to follow the example of the temperature used.
6. complex health care product according to claim 1, it is characterised in that the ganoderma lucidum spore oil includes following component：Three Terpene aliphatic acid, unrighted acid, organic germanium and GL-B.
7. complex health care product according to claim 6, it is characterised in that the ganoderma lucidum spore oil is through ultramicro grinding, CO2It is super Critical extraction, degumming, depickling are prepared from, and the temperature that the supercritical extraction is used is 20- for 25-35 DEG C, pressure 40MPa。
8. complex health care product according to claim 1, it is characterised in that the formulation of the complex health care product is soft capsule Agent.
9. complex health care product according to claim 8, it is characterised in that soft capsule shell master used in the soft capsule To be made up of following component：By weight,
200-500 parts of gelatin, preferably 400-500 parts,
150-300 parts of glycerine, preferably 150-200 parts,
250-500 parts, preferably 400-500 parts of purified water.
10. complex health care product according to claim 9, it is characterised in that the preparation method of the soft capsule shell is：First will Glycerine, purified water mixing, add gained mixture after gelatin and are stirred 1-2 hours at 65-75 DEG C, then stand 2-3 hours, afterwards Cast molding obtains rubber, is molded using capsule machine pelleting.
CN201710481063.7A 2017-06-22 2017-06-22 A kind of complex health care product of relieving mental strain and helping sleep Pending CN107252116A (en)

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CN114984097A (en) * 2022-06-14 2022-09-02 中科健康产业集团股份有限公司 Preparation method and application of antidepressant composition
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