CN107224423A - A kind of hydrosol with whitening function - Google Patents

A kind of hydrosol with whitening function Download PDF

Info

Publication number
CN107224423A
CN107224423A CN201710450297.5A CN201710450297A CN107224423A CN 107224423 A CN107224423 A CN 107224423A CN 201710450297 A CN201710450297 A CN 201710450297A CN 107224423 A CN107224423 A CN 107224423A
Authority
CN
China
Prior art keywords
parts
radix
hydrosol
fresh
ginseng
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710450297.5A
Other languages
Chinese (zh)
Inventor
邹录惠
杨明珠
黄丽凤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangxi Nanning's Biotechnology Co Ltd
Original Assignee
Guangxi Nanning's Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangxi Nanning's Biotechnology Co Ltd filed Critical Guangxi Nanning's Biotechnology Co Ltd
Priority to CN201710450297.5A priority Critical patent/CN107224423A/en
Publication of CN107224423A publication Critical patent/CN107224423A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/78Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The present invention discloses a kind of hydrosol with whitening function.It is achieved by the following technical solution:With containing ginseng, safflower, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, coix seed, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, the extract solution of the herbal mixture of the bletilla striata replaces distilled water to distill fresh flowers and plants, collects distillate, sealing, curing, through membrane filter filtration sterilization, obtained hydrosol, which has, suppresses tyrosinase activity and effect of scavenging radical, and preparation process is without any non-edible chemical composition, excitant is small, has no toxic side effect, and is natural whitening and skin-protecting product.

Description

A kind of hydrosol with whitening function
Technical field
The invention belongs to technical field of skin care, it is related to a kind of hydrosol.
Background technology
Whitening class skin care item are always the main flow in skin care item market in recent years, and traditional whitening product has secondary work mostly With the material such as salicylic acid, 'alpha '-hydroxy acids, vitamin A acid mainly by promoting epiderm skin metabolism to come off, makes melanin companion Skin whitening effect is reached with coming off for horn cell, but it is possible with excitant, skin corrosivity, high concentration long-term use Allergy, inflammation can be caused;There are the accumulation problems of mercury in vivo in alembroth;Hydroquinones are mainly led to as conventional whitening agent Cross and combined with the histidine avtive spot of tyrosinase and reduce pigmentation, but simultaneously also can induced activity oxygen generation so as to Cause the oxidation Decomposition of film fat and albumen, cause irreversible skin pigment to be lost in, existing China has forbidden in whitening class product Use hydroquinones material.
At present, skin-whitening product be typically using tyrosinase as action target spot, by suppress tyrosinase activity or Block tyrosine to generate the oxidative pathway of melanin, so as to reduce the generation of melanin, reach the effect of skin whitening.From junket The experiment of propylhomoserin enzyme inhibitor is generally received by numerous scholars as white-skinned face function is evaluated.The tyrosinase of middle herbal source suppresses Agent, has the advantages that safety, gentle to pigment type skin effectively, is the new direction of whitening and skin-protecting exploitation.
Face skin it is moist, the defeated cloth of operation, body fluid with qi and blood is closely related.Skin relies qi and blood foster to moisten, body fluid To moisten, qi-blood-body fluid virtual loss, then skin is dark and gloomy withered without pool.Traditional Chinese medical theory thinks that facial obscure, color spot is due to gas The reason such as anemia is empty, QI-blood circulation is obstructed, exopathogen attack, caused by dry skin water shortage, selection have promoting qi circulation and removing obstruction in the collateral, Invigorate blood circulation, fill blood, the nourishing medicine of skin is nursed one's health, it is possible to reduce the generation of melanin.
Hydrosol contains the water-soluble substances (such as tannic acid and flavonoids) and a small amount of volatile small molecule material of plant origin, Easily it is less readily available for absorption by the skin, alcohol-free composition is not stimulated gently, toner can be worked as or facial mask is used, is in recent years emerging daily Beauty skin care product.
The content of the invention
The technical problems to be solved by the invention, are to provide a kind of hydrosol with whitening function of natural botanical source.
The technical scheme that the present invention solves above-mentioned technical problem is as follows:
A kind of hydrosol with whitening function, it is characterised in that distilled water is replaced using natural Chinese medicinal herb compound extract Fresh flowers and plants are distilled, wherein the natural Chinese medicinal herb compound includes the composition of following component:5~25 parts of ginseng, safflower 5~15 Part, 10~35 parts of the root of herbaceous peony, 10~35 parts of purple sesame, 15~45 parts of the Radix Astragali, 15~45 parts of Radix Angelicae Sinensis, 15~35 parts of Ligusticum wallichii, radix glycyrrhizae 10~ 20 parts, 25~45 parts of the bighead atractylodes rhizome, 10~30 parts of coix seed, 25~45 parts of radix ampelopsis, 25~45 parts of Poria cocos, 25~45 parts of the larva of a silkworm with batrytis, in vain 10~20 parts of splendid achnatherum.
Preferably, described natural Chinese medicinal herb compound of the invention includes the composition of following component:10~20 parts of ginseng, it is red Spend 10~14 parts, 20~30 parts of the root of herbaceous peony, 20~30 parts of purple sesame, 20~35 parts of the Radix Astragali, 20~35 parts of Radix Angelicae Sinensis, 20~30 parts of Ligusticum wallichii, 12~18 parts of radix glycyrrhizae, 26~35 parts of the bighead atractylodes rhizome, 15~25 parts of coix seed, 30~35 parts of radix ampelopsis, 30~35 parts of Poria cocos, the larva of a silkworm with batrytis 30~ 35 parts, 12~18 parts of the bletilla striata.
Specifically, described natural Chinese medicinal herb compound of the invention includes the composition of following component:15 parts of ginseng, safflower 12 Part, 25 parts of the root of herbaceous peony, 25 parts of purple sesame, 30 parts of the Radix Astragali, 30 parts of Radix Angelicae Sinensis, 25 parts of Ligusticum wallichii, 16 parts of radix glycyrrhizae, 30 parts of the bighead atractylodes rhizome, 20 parts of coix seed, 32 parts of radix ampelopsis, 32 parts of Poria cocos, 32 parts of the larva of a silkworm with batrytis, 16 parts of the bletilla striata.
The preparation method of the above-mentioned hydrosol with whitening function, comprises the following steps:
(1) by ginseng, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, coix seed, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, The bletilla striata is crushed respectively, is mixed after being weighed respectively by formula, is added the safflower of formula ratio;Add the hot-water soak 30 of 10 times of 80 DEG C of amounts After minute, extracted 1~3 hour at 90~100 DEG C, filtration, the dregs of a decoction add 8 times of amount water, and 1~3 is extracted at 90~100 DEG C Hour, filtration merges filtrate twice, and herbal mixture extract solution is made.
(2) fresh flowers and plants are distilled using above-mentioned herbal mixture extract solution;
(3) distillation is stopped when the distillate quality of collection is 1~2.5 times of fresh flowers herbaceous stem amount;
(4) above-mentioned distillate is sealed, puts maturation 45~90 days in freezer;
(5) by the distillate of above-mentioned maturation through membrane filter filtration sterilization, it is qualified to detect, filling, produces.
Described fresh flowers and plants are preferably fresh Damask Rose flower, new fresh Jasmine, fresh bigarabe flower, fresh ginseng Root, fresh centella or fresh purslane.
Described temperature of ice house is preferably 2~6 DEG C.
The aperture of described membrane filter is preferably 0.22 μm.
Compared with prior art, the technical scheme that the present invention is provided has the following advantages that:
1st, distilled using the herbal mixture extract solution available for cosmetics instead of simple distilled water, in gained hydrosol Containing herbal mixture water solubility and volatile small molecule material, with tyrosinase activity and antioxidation is suppressed, while simultaneous Have moisturizing effects, so as to reach the skin care effect of whitening.
2nd, active testing result is shown, present invention gained hydrosol, which has suppression tyrosinase activity and removes free radical, to be made With not adding any non-edible chemical composition, excitant is small, has no toxic side effect, and is natural Skin whitening care cosmeticses.
3rd, the selected herbal mixture of the present invention be《Surgery great achievement》Beautiful face is changed on the basis of dissipating cuts out, the bighead atractylodes rhizome in the side of reservationing, in vain Splendid achnatherum, Poria cocos, the larva of a silkworm with batrytis, radix ampelopsis, the bighead atractylodes rhizome, Poria cocos with it is drying damp and strengthening spleen, preserve youthful looksThe larva of a silkworm with batrytis moistens color, and radix ampelopsis dissipating bind disappears It is swollen, bletilla striataization addiction myogenic, more skin damaged.Arrange in pairs or groups again and the Chinese medicine with clear and definite whitening and skin-protecting effect is found in modern study, improve beautiful White effect.
Contained ginsenoside can improve superoxide dismutase in skin epidermal cells in ginseng of the present invention Activity, removes oxyradical, prevents dry skin to be dehydrated, and increases the elasticity of skin, so that it is tender to play protection skin gloss Effect.
The structure of main active Sydroxy carthamin and tyrosinase substrate L- junket in safflower of the present invention The structure of propylhomoserin is similar, therefore can play significant tyrosinase inhibitory activity.
Purple sesame of the present invention,《Sheng Nong's herbal classic》Described in:" ... strengthening the essence gas, hard muscles and bones, good color.Long Clothes, make light of one's life by commiting suicide not old, macrobiosis angle ... ".Purple sesame water extract has good scavenging action to hydroxy radical, can accelerate cell Regeneration, increases the thickness of skin and increases collagen, reaches plump skin, eliminates the effect of microgroove and wrinkle.
The Radix Astragali of the present invention has effects that tonifying Qi and lifting yang, and modern study shows that isoflavone like substance has anti-in the Radix Astragali Radiation, the effect for removing free radical, can reach sun-proof whitening effect.
Radix Angelicae Sinensis of the present invention has the work(of replenishing and activating blood concurrently, contains the Multiple components such as substantial amounts of volatile oil, organic acid, energy Peripheral vascular, increase blood circulation are expanded, modern study shows that the aqueous solution of Radix Angelicae Sinensis has very strong suppression tyrosinase activity, had There are anti-aging and whitening function.
Ligusticum wallichii of the present invention has work(promoting blood circulation and removing blood stasis, is gas medicine in blood, and the kind face for controlling caused by energy stagnation and blood stasis is dim, face Blister, acne etc..Ligusticum wallichii mainly contains volatile oil and Determination of Organic Acids, and research shows that ligustrazine can suppress melanocyte in very low concentration Cell is bred, and suppresses tyrosinase activity, reaches whitening effect.
Flavone compound can significantly inhibit the activity of tyrosinase, the life of inhibitory activity oxygen in radix glycyrrhizae of the present invention Into so as to suppress the generation of melanin, and reaching whitening effect, given birth to available for cutaneous pigmentation and melanin is prevented after solarization Into being one of conventional raw material of whitening spot-removing class cosmetics.
The bighead atractylodes rhizome of the present invention is the key medicine that ancient prescription is brightened,《Haigoushen》Record:" interarea light is pleased, nti-freckle of preserving youthful looks.”《Newly repair Book on Chinese herbal medicine》Record:" ... it is soaked with Bitters, with the face of wipingImitate pole." bighead atractylodes rhizome is containing volatile oil, modern study shows bighead atractylodes rhizome energy Promote the generation of collagen, the melanocyte activity of suppression, with good water retaining function.
Coix seed of the present invention, name Job's tears, adlay, Semen Coicis etc., it is China's integration of drinking and medicinal herbs Chinese medicine.Li Shizhen (1518-1593 A.D.) exists《This Careless detailed outline》Described in:Coix seed energy " appearance, macrobiosis of making light of one's life by commiting suicide are stayed in beauty treatment ".Among the people, coix seed is used for modulation cleawhite pack or controlled The facial skin diseases such as freckle, " buckwheat slag " spot are treated, evident in efficacy, modern study shows Semen Coicis extract to tyrosinase Inhibiting rate is up to 33.3%.
The bletilla striata of the present invention, with promoting blood circulation and hemostasis, the effect of detumescence and promoting granulation,《Haigoushen》Record:" ... control on face Shao- blisters, make us flesh cunning.”《Compendium of Materia Medica》Record:" bletilla is washed one's face, and is gone" modern study shows that the bletilla striata can suppress melanin The activity of cell, eliminates free radical, the generation of the lipid peroxidation of suppression.
The larva of a silkworm with batrytis of the present invention,《Sheng Nong's herbal classic》Described in:" moist color of going out, face fat can be made ".The larva of a silkworm with batrytis In the nutritious skin effect of the Amino acids that contain, free radical can be removed, lipid peroxidation inhibition is formed, eliminate pigmentation.
Radix ampelopsis of the present invention has clearing heat and detoxicating, carbuncle that disappears dissipating bind, effect of expelling pus and promoting granulation.《Sheng Nong's herbal classic》Note Carry:" main carbuncle swells subcutaneous ulcer sore, dissipating bind gas.”《Haigoushen》Record:" sore blister on face can be controlled.”
Poria cocos of the present invention, clearing damp and promoting diuresis, strengthening spleen and middle warmer, antitoxic heart-soothing and sedative.《Bencao Pinhui Jingyao》Record:" white Fu Siberian cocklebur is end, and honey and, face sore and the black blister of puerpera such as sparrow ovum are treated in surface application.”《Fill a vacancy Handbook of Prescriptions for Emergencies》Record:" control”.Poria cocos is light Dampness removing is oozed, can be dissipated because aqueous vapor is detained the freckle, black dim of face and life.
The root of herbaceous peony of the present invention plays the role of blood-nourishing, can treat sallow complexion, facial colour spot, tarnish.《This warp》 Record:" main perverse trend stomachache, except blood-arthralgia, breaks hard product, controls fever and chills hernia lump in the abdomen, relieve pain, diuresis, QI invigorating." root of herbaceous peony whitening function should Its " removing blood-arthralgia, break hard product " is mainly attributed to, modern study shows that the root of herbaceous peony has removing free radical, oxidation resistant effect.
Embodiment
With reference to embodiment, the invention will be further described.
Embodiment 1
The hydrosol with whitening function of the present embodiment, preparation method comprises the following steps:
Ginseng, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, the bletilla striata are crushed respectively Into coarse powder.Weigh 5 parts of ginseng respectively, 10 parts of the root of herbaceous peony, 10 parts of purple sesame, 15 parts of the Radix Astragali, 15 parts of Radix Angelicae Sinensis, 15 parts of Ligusticum wallichii, 10 parts of radix glycyrrhizae, 25 parts of the bighead atractylodes rhizome, 10 parts of coix seed, 25 parts of radix ampelopsis, 25 parts of Poria cocos, 25 parts of the larva of a silkworm with batrytis, 10 parts of the bletilla striata, mixing adds 5 parts of safflower, put In extractor, after the hot-water soak 30 minutes for adding 10 times of 80 DEG C of amounts, extracted 1 hour at 90 DEG C, filtration, the dregs of a decoction add 8 Amount water, is extracted 1 hour at 90 DEG C again, filtration, merges filtrate twice, obtained herbal mixture extract solution.
200 parts of Fresh ginseng radix is taken, silt is washed away, 1cm segment is cut into, puts in distiller, above-mentioned herbal mixture is added Extract solution, heating is distilled, and is stopped distillation when the distillate of collection is 200 parts, is taken distillate to seal, put in 2 DEG C of freezers Maturation 45 days, the distillate of maturation is degerming through 0.22 micron of filtering with microporous membrane, and it is qualified to detect, filling, produces.
Embodiment 2
The preparation method of the hydrosol with whitening function of the present embodiment, comprises the following steps:
Ginseng, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, the bletilla striata are crushed respectively Into middle powder.25 parts of ginseng, 35 parts of the root of herbaceous peony, 35 parts of purple sesame, 45 parts of the Radix Astragali, 45 parts of Radix Angelicae Sinensis, 35 parts of Ligusticum wallichii, radix glycyrrhizae 20 are weighed respectively Part, 45 parts of the bighead atractylodes rhizome, 30 parts of coix seed, 45 parts of radix ampelopsis, 45 parts of Poria cocos, 45 parts of the larva of a silkworm with batrytis, 20 parts of the bletilla striata, mixing adds safflower 15 Part, put in extractor, after the hot-water soak 30 minutes for adding 10 times of 80 DEG C of amounts, extracted 3 hours at 100 DEG C, filtration, the dregs of a decoction are again 8 times of amount water are added, are extracted 3 hours at 100 DEG C, filtration merges filtrate twice, and herbal mixture extract solution is made.
Take fresh Damask Rose to spend 200 parts, put in distiller, add above-mentioned herbal mixture extract solution, heating is carried out Distillation, stops distillation when the distillate of collection is 500 parts, takes distillate to seal, maturation 90 days in 6 DEG C of freezers are put, by maturation Distillate it is degerming through 0.22 micron of filtering with microporous membrane, detect it is qualified, it is filling, produce.
Embodiment 3
The preparation method of the hydrosol with whitening function of the present embodiment, comprises the following steps:
Ginseng, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, the bletilla striata are crushed respectively Into fine powder.15 parts of ginseng, 25 parts of the root of herbaceous peony, 25 parts of purple sesame, 30 parts of the Radix Astragali, 30 parts of Radix Angelicae Sinensis, 25 parts of Ligusticum wallichii, radix glycyrrhizae 16 are weighed respectively Part, 30 parts of the bighead atractylodes rhizome, 20 parts of coix seed, 32 parts of radix ampelopsis, 32 parts of Poria cocos, 32 parts of the larva of a silkworm with batrytis, 16 parts of the bletilla striata, mixing adds safflower 12 Part, put in extractor, after the hot-water soak 30 minutes for adding 10 times of 80 DEG C of amounts, extracted 2 hours at 100 DEG C, filtration, the dregs of a decoction are again 8 times of amount water are added, are extracted 1 hour at 100 DEG C, filtration merges filtrate twice.
Fresh 200 parts of centella is taken, silt is washed away, is cut into 1cm segment, puts in distiller, above-mentioned herbal mixture is added Extract solution, heating is distilled, and is stopped distillation when the distillate of collection is 200 parts, is put maturation 60 days in Cool Room 4 DEG C, will be ripe Into distillate it is degerming through 0.22 micron of filtering with microporous membrane, detect it is qualified, it is filling, produce.
Embodiment 4
The tyrosinase activity inhibitory action to hydrosol obtained by above-described embodiment 1,2,3 is measured respectively.
(1) preparation of solution
1) preparation of phosphate buffer (PBS):Disodium hydrogen phosphate 71.6g and sodium dihydrogen phosphate are accurately weighed respectively 31.2g, plus deionized water are fully dissolved, and the solution that constant volume in 1000mL measuring bottles is configured to 0.2mol/L is transferred to respectively, with 51: 49 ratio is well mixed, and pH is adjusted to 6.8, produces.
2) preparation of tyrosinase solution:A certain amount of 920U/mg tyrosinases are accurately weighed, are made into PBS dissolvings 200u/mg enzyme liquid, is positioned over -20 DEG C of preservations of refrigerator, need to be thawed before at 4 DEG C standby.
3) preparation of DOPA solution:Precision weighs a certain amount of L-3,4 dihydroxyphenylalanine amine, first adds a small amount of 0.1mol/L hydrochloric acid solution pre- Dissolving, adds PBS dilutions to be configured to 1.5g/L dopamine solutions, is placed at 4 DEG C and is kept in dark place again until completely dissolved.
(2) assay method
Phosphate buffer (pH6.8,0.1mol/L), hydrosol sample liquid, tyrosinase solution are separately added into each test tube, 37 DEG C of water-bath 10min are put, DOPA solution 1mL is rapidly added respectively, mixes, 10min is reacted in 37 DEG C of water-baths, in 475nm Lower survey absorbance.It is blank control that experimental system, which is shown in Table 1, C1, and C2 returns to zero for blank, and T1 is sample cell, and T2 is used for sample Zeroing.
The reaction system of the tyrosinase Inhibition test of table 1
Tyrosinase inhibition rate is calculated as follows:
Tyrosinase inhibition rate (%)=(AC1-AT1)/AC1× 100%
In formula, AC1For the absorbance of blank control group;AT1For the absorbance of sample sets.
(3) measurement result
Measurement result shows that gained hydrosol has different degrees of tyrosinase inhibitory activity in embodiment 1,2,3, as a result It is shown in Table 2.
The tyrosinase inhibitory activity measurement result of table 2
Embodiment 5
Hydrosol obtained by above-described embodiment 1,2,3 is measured to the Scavenging activity of DPPH free radicals respectively.
(1) preparation of DPPH free-atom aqueous solutions
A certain amount of DPPH is accurately weighed, plus ethanol is made into concentration about 0.04g/L DPPH solution, is placed in lucifuge at 4 DEG C and protects Deposit.
(2) assay method
Precision pipettes DPPH free-atom aqueous solutions and each 2mL of absolute ethyl alcohol in same test tube, and lucifuge is stood after mixing 20min, determines absorbance A at 517nmc.Precision pipettes DPPH free-atom aqueous solutions and each each 2mL of hydrosol sample liquid in same examination Lucifuge stands 20min after Guan Zhong, mixing, and absorbance A i is determined at 517nm, and precision pipettes absolute ethyl alcohol and each for reagent liquid 2mL is in same test tube, and lucifuge stands 20min after mixing, and absorbance A is determined at 517nmj
The removing power of DPPH free radicals is calculated as follows:
Clearance rate=[1- (Ai-Aj)/Ac] × 100%
(3) measurement result
Measurement result shows that gained hydrosol has different degrees of removing energy to DPPH free radicals in embodiment 1,2,3 Power, the results are shown in Table 3.
The DPPH Scavenging activity measurement results of table 3

Claims (8)

1. a kind of hydrosol with whitening function, it is characterised in that steamed using natural Chinese medicinal herb compound extract instead of distilled water Fresh flowers and plants are evaporated, wherein the natural Chinese medicinal herb compound includes the composition of following component:5~25 parts of ginseng, 5~15 parts of safflower, 10~35 parts of the root of herbaceous peony, 10~35 parts of purple sesame, 15~45 parts of the Radix Astragali, 15~45 parts of Radix Angelicae Sinensis, 15~35 parts of Ligusticum wallichii, radix glycyrrhizae 10~20 Part, 25~45 parts of the bighead atractylodes rhizome, 10~30 parts of coix seed, 25~45 parts of radix ampelopsis, 25~45 parts of Poria cocos, 25~45 parts of the larva of a silkworm with batrytis, the bletilla striata 10~20 parts.
2. the hydrosol according to claim 1 with whitening function, it is characterised in that described natural Chinese medicinal herb compound bag Include the composition of following component:10~20 parts of ginseng, 10~14 parts of safflower, 20~30 parts of the root of herbaceous peony, 20~30 parts of purple sesame, the Radix Astragali 20~ 35 parts, 20~35 parts of Radix Angelicae Sinensis, 20~30 parts of Ligusticum wallichii, 12~18 parts of radix glycyrrhizae, 26~35 parts of the bighead atractylodes rhizome, 15~25 parts of coix seed, radix ampelopsis 30~35 parts, 30~35 parts of Poria cocos, 30~35 parts of the larva of a silkworm with batrytis, 12~18 parts of the bletilla striata.
3. the hydrosol according to claim 1 or 2 with whitening function, it is characterised in that described natural Chinese medicinal herb is answered Side includes the composition of following component:15 parts of ginseng, 12 parts of safflower, 25 parts of the root of herbaceous peony, 25 parts of purple sesame, 30 parts of the Radix Astragali, 30 parts of Radix Angelicae Sinensis, river 25 parts of rhizome of chuanxiong, 16 parts of radix glycyrrhizae, 30 parts of the bighead atractylodes rhizome, 20 parts of coix seed, 32 parts of radix ampelopsis, 32 parts of Poria cocos, 32 parts of the larva of a silkworm with batrytis, 16 parts of the bletilla striata.
4. a kind of preparation method of the hydrosol with whitening function, it is characterised in that comprise the following steps:
(1) add distilled water to be decocted the natural Chinese medicinal herb compound described in claims 1 to 3, herbal mixture extract solution is made;
(2) fresh flowers and plants are distilled using above-mentioned herbal mixture extract solution;
(3) distillation is stopped when the distillate quality of collection is 1~2.5 times of fresh flowers herbaceous stem amount;
(4) above-mentioned distillate is sealed, puts maturation 45~90 days in freezer;
(5) by the distillate of above-mentioned maturation through membrane filter filtration sterilization, it is qualified to detect, filling, produces.
5. a kind of preparation method of hydrosol with whitening function according to claim 4, it is characterised in that the step (1) preparation method of herbal mixture extract solution is:By ginseng, the root of herbaceous peony, purple sesame, the Radix Astragali, Radix Angelicae Sinensis, Ligusticum wallichii, radix glycyrrhizae, the bighead atractylodes rhizome, Job's tears Benevolence, radix ampelopsis, Poria cocos, the larva of a silkworm with batrytis, the bletilla striata are crushed respectively, are mixed after being weighed respectively by formula, are added the safflower of formula ratio;Add 10 After the hot-water soak 30 minutes of times 80 DEG C of amount, extracted 1~3 hour at 90~100 DEG C, filtration, the dregs of a decoction add 8 times of amount water, Extracted 1~3 hour at 90~100 DEG C, filtration merges filtrate twice.
6. preparation method according to claim 4, it is characterised in that the fresh flowers and plants of the step (2) are fresh big horse Scholar's leather rose, new fresh Jasmine, fresh bigarabe flower, Fresh ginseng radix, fresh centella or fresh purslane.
7. preparation method according to claim 4, it is characterised in that the temperature low hold of freezer is 2 in the step (4) ~6 DEG C.
8. preparation method according to claim 4, it is characterised in that the aperture of membrane filter is in the step (5) 0.22μm。
CN201710450297.5A 2017-06-15 2017-06-15 A kind of hydrosol with whitening function Pending CN107224423A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710450297.5A CN107224423A (en) 2017-06-15 2017-06-15 A kind of hydrosol with whitening function

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710450297.5A CN107224423A (en) 2017-06-15 2017-06-15 A kind of hydrosol with whitening function

Publications (1)

Publication Number Publication Date
CN107224423A true CN107224423A (en) 2017-10-03

Family

ID=59935395

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710450297.5A Pending CN107224423A (en) 2017-06-15 2017-06-15 A kind of hydrosol with whitening function

Country Status (1)

Country Link
CN (1) CN107224423A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107737272A (en) * 2017-12-03 2018-02-27 同济大学 A kind of Chinese medicine composition and its methods for making and using same with freckle removing and whitening effect
CN107982174A (en) * 2017-12-22 2018-05-04 陈彦蓉 A kind of distillation and preparation method thereof of clearing heat for detumescence, Whitening, spot
CN108085187A (en) * 2018-01-16 2018-05-29 山西大学 A kind of Radix Astragali whitening and skin-protecting soap and its preparation process
CN108309918A (en) * 2018-05-08 2018-07-24 郑州克拉时光美容服务有限公司 A kind of whitening spot-removing face mask of traditional Chinese medicine
CN108815041A (en) * 2018-08-15 2018-11-16 王国香 A kind of hydrosol and its preparation method and application for beauty treatment of invigorating blood circulation
CN108904394A (en) * 2018-09-21 2018-11-30 广州市科能化妆品科研有限公司 A kind of Chinese medicine composition and preparation method
CN110393693A (en) * 2019-08-27 2019-11-01 万红军 The net skin beauty face-whitening-nourishing facial mask of nti-freckle and preparation method that one Plant Extracts extract
CN111419747A (en) * 2020-04-18 2020-07-17 北温草生物科技(上海)有限公司 Chinese herbal medicine composition for whitening and brightening skin
CN112933013A (en) * 2021-03-06 2021-06-11 广州中草世家化妆品有限公司 Herbal whitening and skin-brightening composition rich in ginseng essence and preparation method thereof
CN114224802A (en) * 2021-12-31 2022-03-25 上海智勇教育培训有限公司 Long-acting fresh-keeping skin-care type hydrolat based on natural traditional Chinese medicines and preparation method thereof
CN115778887A (en) * 2022-12-09 2023-03-14 波顿香料股份有限公司 Whitening and sunscreen functional composition, preparation method thereof and whitening cream

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101804185A (en) * 2010-03-24 2010-08-18 张宁 Chinese medicinal compound extract for whitening and removing freckles and preparation method thereof
CN101849899A (en) * 2009-12-24 2010-10-06 上海原尚草化妆品有限公司 Chinese medicinal compound extract and cosmetics comprising same as active ingredient
CN102406209A (en) * 2011-11-28 2012-04-11 新疆和田阳光沙漠玫瑰有限公司 Liquid drink containing active ingredients of rose essential oil and preparation method for liquid drink
CN104013566A (en) * 2013-02-28 2014-09-03 香港浸会大学 Traditional Chinese medicine composition with whitening effect, preparation method thereof and beautification application thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849899A (en) * 2009-12-24 2010-10-06 上海原尚草化妆品有限公司 Chinese medicinal compound extract and cosmetics comprising same as active ingredient
CN101804185A (en) * 2010-03-24 2010-08-18 张宁 Chinese medicinal compound extract for whitening and removing freckles and preparation method thereof
CN102406209A (en) * 2011-11-28 2012-04-11 新疆和田阳光沙漠玫瑰有限公司 Liquid drink containing active ingredients of rose essential oil and preparation method for liquid drink
CN104013566A (en) * 2013-02-28 2014-09-03 香港浸会大学 Traditional Chinese medicine composition with whitening effect, preparation method thereof and beautification application thereof

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107737272A (en) * 2017-12-03 2018-02-27 同济大学 A kind of Chinese medicine composition and its methods for making and using same with freckle removing and whitening effect
CN107982174A (en) * 2017-12-22 2018-05-04 陈彦蓉 A kind of distillation and preparation method thereof of clearing heat for detumescence, Whitening, spot
CN108085187A (en) * 2018-01-16 2018-05-29 山西大学 A kind of Radix Astragali whitening and skin-protecting soap and its preparation process
CN108309918A (en) * 2018-05-08 2018-07-24 郑州克拉时光美容服务有限公司 A kind of whitening spot-removing face mask of traditional Chinese medicine
CN108815041A (en) * 2018-08-15 2018-11-16 王国香 A kind of hydrosol and its preparation method and application for beauty treatment of invigorating blood circulation
CN108904394B (en) * 2018-09-21 2020-08-07 广州市科能化妆品科研有限公司 Traditional Chinese medicine composition and preparation method thereof
CN108904394A (en) * 2018-09-21 2018-11-30 广州市科能化妆品科研有限公司 A kind of Chinese medicine composition and preparation method
CN110393693A (en) * 2019-08-27 2019-11-01 万红军 The net skin beauty face-whitening-nourishing facial mask of nti-freckle and preparation method that one Plant Extracts extract
CN111419747A (en) * 2020-04-18 2020-07-17 北温草生物科技(上海)有限公司 Chinese herbal medicine composition for whitening and brightening skin
CN112933013A (en) * 2021-03-06 2021-06-11 广州中草世家化妆品有限公司 Herbal whitening and skin-brightening composition rich in ginseng essence and preparation method thereof
CN112933013B (en) * 2021-03-06 2022-02-18 广州中草世家化妆品有限公司 Herbal whitening and skin-brightening composition rich in ginseng essence and preparation method thereof
CN114224802A (en) * 2021-12-31 2022-03-25 上海智勇教育培训有限公司 Long-acting fresh-keeping skin-care type hydrolat based on natural traditional Chinese medicines and preparation method thereof
CN115778887A (en) * 2022-12-09 2023-03-14 波顿香料股份有限公司 Whitening and sunscreen functional composition, preparation method thereof and whitening cream
CN115778887B (en) * 2022-12-09 2024-03-19 波顿香料股份有限公司 Whitening and sun-screening efficacy composition and preparation method thereof

Similar Documents

Publication Publication Date Title
CN107224423A (en) A kind of hydrosol with whitening function
CN103565730B (en) A kind of scented tea body whitening crème and manufacture method thereof
CN102258442B (en) Compound traditional Chinese medicine extract and application thereof to whitening, moisturizing and anti-aging skin care product
CN103919711B (en) A kind of anti-ageing whitening cream of oolong tea and manufacture method thereof
CN101804185B (en) Chinese medicinal compound extract for whitening and removing freckles and preparation method thereof
CN104434618B (en) Have whitening, nti-freckle concurrently and print nine grass green frosts of effect and preparation method thereof
CN102274141B (en) Herba selaginellae revival moisturizing cream and preparation method thereof
KR101387308B1 (en) Skin whitening composition by using of dendropanax morbifera ferment extract
CN110507582A (en) A kind of anti-ageing remediation composition and its preparation method and application containing composite vegetables extractive
CN102846499B (en) Composition having effects of whitening, removing spots and refreshing skin
CN105342908A (en) Centella asiatica beauty and anti-wrinkle traditional Chinese medicinal ointment for relieving wrinkles and preparation method of traditional Chinese medicinal ointment
CN105496917A (en) Herba centellae anti-wrinkling face cream and preparation method thereof
CN109157447A (en) Application and preparation method of the Fructus Rosae Laevigatae extract in skin whitening, moisturizing anti-aging skin care product
KR100564108B1 (en) Cosmetic composition comprising plant extract having anti-aging effect
CN108618975A (en) A kind of Chinese medicine compound prescription facial masks for whitening faces and removing spots and preparation method thereof
CN110393693A (en) The net skin beauty face-whitening-nourishing facial mask of nti-freckle and preparation method that one Plant Extracts extract
CN101234132A (en) New use of angelica sinensis or its extract in preparing skin care products
CN110075053A (en) A kind of compound pilose antler moisturizing whitening mask and preparation method thereof suitable for plateau crowd
WO2015010373A1 (en) Facial mask used for treatment of acne hyperpigmentation spot and for whitening
CN110664679B (en) Traditional Chinese medicine composition with whitening and anti-aging effects and preparation method and application thereof
CN106511249A (en) Plant facial mask with efficacies of preserving moisture and whitening skin
CN108938511B (en) Composition of natural plant extracts and application of composition in skin moisturizing and acne removing products
CN110339127A (en) A kind of cosmetics and its composition, preparation method and the purposes for improving skin function
CN105816663A (en) Traditional Chinese medicine composition with nutrition and anti-aging effects and facial cream and preparation methods thereof
CN109431951A (en) A kind of Chinese medicine lightening compositions and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20171003