CN110075053A - A kind of compound pilose antler moisturizing whitening mask and preparation method thereof suitable for plateau crowd - Google Patents

A kind of compound pilose antler moisturizing whitening mask and preparation method thereof suitable for plateau crowd Download PDF

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Publication number
CN110075053A
CN110075053A CN201910459886.9A CN201910459886A CN110075053A CN 110075053 A CN110075053 A CN 110075053A CN 201910459886 A CN201910459886 A CN 201910459886A CN 110075053 A CN110075053 A CN 110075053A
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parts
pilose antler
compound
preparation
distilled water
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杨旭忠
黄渊淼
闫佳龙
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Gansu Tianzhishan Biotechnology Co Ltd
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Gansu Tianzhishan Biotechnology Co Ltd
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Priority to CN201910459886.9A priority Critical patent/CN110075053A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

Abstract

The compound pilose antler moisturizing whitening mask and preparation method thereof that the invention discloses a kind of suitable for plateau crowd, raw material including following parts by weight is made: 5-10 parts of pilose antler, 10-20 parts of aloe, 10-20 parts of the bletilla striata, 10-20 parts of the root of Dahurain angelica, 20-30 parts of Radix Angelicae Sinensis, 20-30 parts of honey, 25-50 parts of glycerol, 1,20-40 parts of 3- butanediol, 1-2 parts of hyaluronic acid, 1-2 parts of propylben, distilled water adds to 1000 parts;Compound pilose antler moisturizing whitening mask of the present invention not only has moisture-keeping functions, but also has the function of whitening and nourishes rough skin, and the red capillary that can be relieved plateau crowd's skin surface, the skin care especially suitable for plateau crowd is used for a long time.

Description

A kind of compound pilose antler moisturizing whitening mask and preparation method thereof suitable for plateau crowd
Technical field
The present invention relates to cosmetic technical fields, and in particular to a kind of compound pilose antler moisturizing whitening suitable for plateau crowd Facial mask and preparation method thereof.
Background technique
The principle of facial mask is exactly that extraneous air pollution is temporarily isolating using the of short duration time for being covered on face, improves skin Temperature expands skin pore, promotes sweat gland secretion, increase skin oxygen content, and it is newly old to be conducive to skin exclusion superficial cell The product of metabolism and the oil substances of accumulation, the moisture in facial mask penetrate into the cuticula of epidermis, and skin becomes soft, skin from It is so bright;On the other hand, it can be protected containing inhibiting melanin to form the benefit materials with free radical resisting commonly using facial mask in facial mask Hold that skin is pure white and high resilience.
With the rapid development of our country's economy, the common people are also higher and higher to the degree of concern of appearance instrument.Based on this, in recent years China's cosmetic industry is developed rapidly.The layout characteristics of China's cosmetics industrial enterprise are presented southeastern coast and concentrate, to The trend that Midwest gradually decreases.Western plateau climate environment presentation oxygen content is relatively low, dry, ultraviolet light is strong, winter is cold Cold windy feature, western outwork person are influenced by living environment, and dry, dark yellow, coarse state is presented in skin.By Currently, for the facial mask of western crowd's skin care, proportion is very little in numerous cosmetics patents at home.Therefore, will The audient crowd of facial mask research and development is positioned as the universal poor plateau crowd of skin condition and seems very necessary.
Summary of the invention
It is particularly suitable the purpose of the present invention is to provide a kind of compound pilose antler moisturizing whitening mask suitable for plateau crowd In plateau, what crowd used has both the facial mask of moisturizing and whitening function.
Another object of the present invention is providing a kind of preparation of compound pilose antler moisturizing whitening mask suitable for plateau crowd Method.
To achieve the above object, a kind of the technical solution adopted by the present invention are as follows: compound pilose antler guarantor suitable for plateau crowd Wet whitening mask, the raw material including following parts by weight are made: 5-10 parts of pilose antler, 10-20 parts of aloe, and 10-20 parts of the bletilla striata, the root of Dahurain angelica 10-20 parts, 20-30 parts of Radix Angelicae Sinensis, 20-30 parts of honey, 25-50 parts of glycerol, 20-40 parts of 1,3-BDO, 1-2 parts of hyaluronic acid, 1-2 parts of propylben, distilled water adds to 1000 parts.
Preferably, the raw material including following parts by weight is made: 7 parts of pilose antler, 15 parts of aloe, and 15 parts of the bletilla striata, 15 parts of the root of Dahurain angelica, when Return 25 parts, 25 parts of honey, 35 parts of glycerol, 30 parts of 1,3-BDO, 1.5 parts of hyaluronic acid, 1.5 parts of propylben, distilled water Add to 1000 parts.
A kind of preparation method of the compound pilose antler moisturizing whitening mask suitable for plateau crowd, includes the following steps:
Step A, above-mentioned raw materials are weighed according to parts by weight;
Step B, extracting solution is uniformly mixed by extraction pilose antler, aloe, the bletilla striata, the root of Dahurain angelica, the extracting solution that Radix Angelicae Sinensis mentions;
Step C, honey, glycerol, 1,3-BDO, hyaluronic acid, propylben are added in step B mixed liquor, so Afterwards plus distilled water dilutes to obtain compound pilose antler moisturizing whitening mask stoste;
Step D, the stoste in step C is packed into the facial mask bag for being placed with silk mask paper, is sealed up to the moisturizing of compound pilose antler Whitening mask.
Preferably, in the step B pilose antler extracting solution preparation: after weighed velvet powder filter paper packaging, be placed in In Soxhlet extractor, distilled water is added, extracts 4h, filtrate is collected in filtering, and filtrate is pilose antler extracting solution.
Preferably, in the step B extract solution from aloe preparation: Chinese aloe leaf is shredded, blender is put into and carries out broken place Reason obtains highly viscous aloe liquid, and 10mg alpha-amylase is added, and after being sufficiently stirred, places it in 55 DEG C of constant temperature 4h, 95% second is added Alcohol shakes up, and in being placed at room temperature for 48h, removes precipitating, ethyl alcohol is removed under reduced pressure, and residue adds distilled water ultrasonic dissolution, filtering, filtrate For extract solution from aloe.
Preferably, in the step B bletilla striata extract, root of Dahurain angelica extracting solution, angelica extract preparation: will be weighed white Splendid achnatherum, the root of Dahurain angelica, Chinese Angelica Root first use distilled water circumfluence distillation 2h, reuse distilled water and repeat to extract 1 time, combined extract, and 60 It DEG C is concentrated under reduced pressure, dehydrated alcohol is added in concentrate, shakes up, removes precipitating, is removed under reduced pressure ethyl alcohol, residue addition is appropriate to steam Distilled water ultrasonic dissolution, filtering, filtrate is the extracting solution.
Pilose antler is the young horn of the unossified dense villus of stag of animal in deer family sika deer or red deer, a kind of to be of great rarity Medicinal material.Theory of traditional Chinese medical science thinks that pilose antler energy invigorating kidney yang, benefiting essence-blood, strengthening the bones and muscles, preserve youthful looks happy color, QI invigorating are reposed, these effects prompt deer Young pilose antler has good skin care action;Modern medical research has found that pilose antler energy rapid desufflation blood vessel, realizes automatic hemostasis, generates Anti-inflammatory factors boost metabolism, and repair nerve and play specific anti-inflammatory effect, therefore pilose antler can alleviate plateau crowd The red capillary of skin surface promotes skin metabolism, keeps elasticity of skin.It is additionally added activating microcirculation and removing stasis medicinal in this facial mask prescription, dredges through logical Network inhibits the Chinese medicine of tyrosinase and anti-oxidant free radical resisting effect, acts synergistically with pilose antler, play altogether the clean vigorous and graceful health of skin it Effect.
Pilose antler in the present invention suitable for the compound pilose antler moisturizing whitening mask of plateau crowd contains phosphatide, glycolipid, glue The effect of ingredients such as rouge, fatty acid, amino acid, protein and calcium, phosphorus, magnesium, sodium have vasoconstriction, nourish face;Radix Angelicae Sinensis mentions It takes liquid that can effectively remove free radical, removes pigmentation, there is whitening function;The root of Dahurain angelica, the bletilla striata play auxiliary to skin-whitening Effect;Honey and aloe main function are to improve moisture content of skin, play moisture-keeping function, and make with certain antibacterial With.
The invention has the benefit that compound pilose antler moisturizing whitening mask not only has moisture-keeping functions, but also there is whitening and taste The function of skin is supported, the red capillary that also can be relieved plateau crowd's skin surface, the skin especially suitable for plateau crowd is used for a long time Skin maintenance.
Detailed description of the invention
Scheme first is that different tests sample is to tyrosinase inhibition rate;
Scheme second is that different tests sample is to Scavenging action to hydroxyl free radical;
Scheme third is that different tests sample is to DPPH clearance rate.
Specific embodiment
The present invention is described in further detail below by specific embodiment and in conjunction with attached drawing.
Embodiment 1
A kind of compound pilose antler moisturizing whitening mask suitable for plateau crowd, is made of: pilose antler the raw material of following parts by weight 7g, Radix Angelicae Sinensis 25g, aloe 15g, root of Dahurain angelica 15g, bletilla striata 1.5g, honey 2.5g, glycerol 5g, 1,3 butylene glycol 4g, hyaluronic acid 0.1g, propylben 0.1g, add distilled water to 100g be high dose group compound pilose antler moisturizing whitening mask.
Specific preparation method, includes the following steps:
Step A, above-mentioned raw materials are weighed according to parts by weight;
Step B, extracting solution is uniformly mixed by extraction pilose antler, aloe, the bletilla striata, the root of Dahurain angelica, the extracting solution that Radix Angelicae Sinensis mentions;
Step C, honey, glycerol, 1,3-BDO, hyaluronic acid, propylben are added in step B mixed liquor, so Afterwards plus distilled water dilutes to obtain compound pilose antler moisturizing whitening mask stoste;
Step D, the stoste in step C is packed into the facial mask bag for being placed with silk mask paper, is sealed up to the moisturizing of compound pilose antler Whitening mask.
The wherein preparation of pilose antler extracting solution: weighing velvet powder 7g, after filter paper packaging, is placed in Soxhlet extractor, adds Enter 50mL distilled water, extract 4h, filtrate is collected in filtering, and adding distilled water to adjust to total volume is 100mL, spare.
The preparation of extract solution from aloe: 15g Chinese aloe leaf is shredded, and is put into blender and is carried out break process, obtains highly viscous reed Luxuriant growth liquid.10mg alpha-amylase is added, after being sufficiently stirred, places it in 55 DEG C of constant temperature 4h, viscosity reduces.95% ethyl alcohol is added 10mL shakes up, and in being placed at room temperature for 48h, removes precipitating, ethyl alcohol is removed under reduced pressure, and residue adds distilled water ultrasonic dissolution, filters, filter It is 100mL that liquid, which is adjusted to total volume, spare.
The preparation of bletilla striata extract, root of Dahurain angelica extracting solution, angelica extract: the root of Dahurain angelica and each 15g of common bletilla, angelica powder are weighed Last 25g first uses 300mL distilled water circumfluence distillation 2h, reuses 200mL distilled water and repeats to extract 1 time, combined extract, and 60 DEG C it is concentrated under reduced pressure into volume about 100mL.The dehydrated alcohol of 300mL is added in concentrate, shakes up, removes precipitating, is removed under reduced pressure Ethyl alcohol, residue add appropriate distilled water ultrasonic dissolution, filtering, and it is 300mL that filtrate, which adjusts to total volume, spare.
It is accurate to measure pilose antler extracting solution, each 10mL of extract solution from aloe, bletilla striata extract, root of Dahurain angelica extracting solution, angelica extract The total 30mL of extract (is equivalent to crude drug pilose antler 0.7g, aloe 1.5g, bletilla striata 1.5g, root of Dahurain angelica 1.5g, Radix Angelicae Sinensis 2.5g), is added 3.0g honey, glycerol 4.0g, 1,3-BDO 4.0g, hyaluronic acid 0.2g, propylben 0.2g add distilled water to 100g, Up to high dose group pilose antler moisturizing whitening mask stoste.
Low dose group compound pilose antler moisturizing whitening mask prescription: pilose antler 0.5g, aloe 1.0g, bletilla striata 1g, root of Dahurain angelica 1.0g, when Return 1.5g, honey 2.0g, glycerol 3.0g, 1,3-BDO 3g, hyaluronic acid 0.1g, propylben 0.1g, adds distilled water extremely 100g。
The specific preparation step of low dose group compound pilose antler moisturizing whitening mask stoste is same as above.
The preparation of 2. experimental control sample -1 of embodiment:
Prescription: pilose antler 0.7g, aloe 1.5g, honey 2.5g, glycerol 5g, 1,3 butylene glycol 4g, hyaluronic acid 0.1g, Ni Bo Golden propyl ester 0.1g, adds distilled water to 100g.
Preparation: in addition to Radix Angelicae Sinensis, the root of Dahurain angelica, bletilla striata extract is not added, other specific preparation steps are the same as " compound pilose antler moisturizing whitening The specific preparation step of facial mask stoste ".
The preparation of 3. experimental control sample -2 of embodiment:
Prescription: aloe 1.5g, honey 2.5g, glycerol 5g, 1,3 butylene glycol 4g, hyaluronic acid 0.1g, propylben 0.1g adds distilled water to 100g.
Preparation: in addition to pilose antler, Radix Angelicae Sinensis, the root of Dahurain angelica, bletilla striata extract is not added, other specific preparation steps are the same as " compound pilose antler is protected The wet specific preparation step of whitening mask stoste ".
The preparation of 4. experimental control sample -3 (solvent) of embodiment:
Prescription: glycerol 5g, 1,3-BDO 4g, hyaluronic acid 0.1g, propylben 0.1g add distilled water to 100g.
Preparation: pilose antler, Radix Angelicae Sinensis, aloe, the root of Dahurain angelica, bletilla striata extract and honey is not added, by recipe quantity glycerol, 1,3- fourth two Alcohol, hyaluronic acid, propylben add in appropriate distilled water, stirring and dissolving, then plus distilled water be diluted to 100g.
The ability having below by the experimental method verifying present invention.
One, tyrosinase activity inhibits test
Sequentially added in 10mL centrifuge tube 3mL 0.05% (w/v) l-tyrosine, 4mL pH 6.8 phosphate buffer, Each test specimen of 0.3mL shakes up and heats 10min in 37 DEG C of water-baths, adds 1mL 500U/ml tyrosinase, continues to heat 5min, 12000r/min are centrifuged 5min, and supernatant is taken to measure light absorption value (A at 475nm1), sample is replaced with phosphate buffer Measure light absorption value (A2).The inhibiting rate of tyrosinase is calculated according to the following formula in test specimen:
Each test specimen is as shown in Figure 1 to the inhibiting rate of tyrosinase.Inhibiting rate is from high to low successively are as follows: high dose group > - 2 > experimental control sample -3 of -1 > experimental control sample of low dose group > experimental control sample.Compound pilose antler moisturizing whitening mask The tyrosinase inhibitory effect of stoste high and low dose group is superior to test control group, and solvent group inhibits to live almost without tyrosinase Property.The above results prompt compound pilose antler moisturizing whitening mask stoste to have good tyrosinase rejection ability, have centainly Whitening function.
Two, scavenging hydroxyl is tested
It is measured using Fenton method: taking 7 25mL colorimetric cylinders, it is adjacent that 0.3mL 7.5mmol/L is added in 1-7 colorimetric cylinder Ferrosin solution, 1mL pH4.5Tris-HCl buffer solution, 0.3mL 7.5mmol/L l ferrous ammonium sulfate solution;In No. 1 pipe 50% ethanol solution is added as reference solution, 0.2mL 7.5mmol/L H2O2 is added in 2-7 colorimetric cylinder, at No. 3-7 It is separately added into each test specimen 0.3mL in colorimetric cylinder, is settled to scale with 50% ethyl alcohol, in 37 DEG C of water-bath, reacts 1h, Absorbance is surveyed at 536nm wavelength, calculates the clearance rate of hydroxy radical.Wherein clearance rate is calculated according to the following formula:
In formula: AIt does not damageFor H is not added2O2Hydroxy radical system (i.e. Fe2+/ Phen solution) absorbance (No. 1 Pipe);ADamageFor H is added2O2Hydroxy radical system (i.e. Fe2+/ Phen+H2O2) absorbance (No. 2 pipe);ASampleFor test sample Hydroxy radical system (the i.e. Fe of product2+/ Phen+H2O2+ test specimen) absorbance (No. 3-7 pipe).It is tested in 3-7 pipe Sample is followed successively by the high and low concentration samples of compound pilose antler moisturizing whitening mask, experimental control sample -1, experimental control sample -2 and examination Test control sample -3.
Each test specimen is as shown in Figure 2 to the clearance rate of hydroxy radical.The ability of each sample scavenging hydroxyl by greatly to It is small are as follows: -2 > experimental control sample -3 of -1 > experimental control sample of high dose group > low dose group > experimental control sample.High agent The ability of amount group scavenging hydroxyl is higher than low dose group;The Hydroxyl radical-scavenging energy of compound pilose antler moisturizing whitening mask stoste group Power is superior to test control group;Vehicle controls are almost without Hydroxyl radical-scavenging ability.The above results prompt the moisturizing of compound pilose antler Whitening mask stoste has good scavenging hydroxyl ability, has certain antioxidation.
Three, DPPH (DPPH.free radical) test is removed
It is 1 × 10 that DPPH, which is configured to concentration with 50% ethyl alcohol,-3The mother liquor of mol/L is stored in 0~4 DEG C.Used time is by mother liquor It is diluted to 1 × 10-4mol/L.In No. 1 colorimetric cylinder 50% ethanol solution is added as reference solution in the colorimetric cylinder number branch for taking 25mL, 2mL DPPH solution (A is added in No. 2 colorimetric cylindersc), 2mL DPPH solution is added in No. 3-7 and compound pilose antler whitening is protected Wet facial mask high and low dose group and experimental control sample 0.5mL (Ai), compound pilose antler whitening is only added in 3'-7' colorimetric cylinder Moisture saver mask high and low dose group and experimental control sample 0.5mL (Aj), it is settled to scale with 50% ethyl alcohol respectively, at room temperature Stand 30min.At maximum wavelength (517nm), each absorbance is measured.Wherein clearance rate is calculated according to the following formula:
In formula: AcFor not plus test specimen DPPH solution absorbance (No. 2 colorimetric cylinders);AiFor the alcoholic solution containing DPPH The absorbance (3-7 colorimetric cylinder) of test sample solution;AjFor the absorbance of the test sample solution without DPPH alcoholic solution (3'-7' colorimetric cylinder).3-7 pipe is respectively compound pilose antler whitening moisturizing face masque high and low dose group, experimental control sample -1, examination Test control sample -2, experimental control sample -3.It is respectively that 3-7 manages the corresponding alcoholic solution test sample without DPPH in 3'-7' pipe Product.
Each test specimen is as shown in Figure 3 to the clearance rate of DPPH.The ability that each sample removes DPPH is descending are as follows: high agent - 2 > experimental control sample -3 of -1 > experimental control sample of amount group > low dose group > experimental control sample.High dose group is removed The ability of DPPH is higher than low dose group, and the two is above test control group to the Scavenging activity of DPPH, and Vehicle controls almost do not have There is DPPH Scavenging activity.It prompts compound pilose antler moisturizing whitening mask stoste that there is good removing DPPH ability, has centainly Antioxidation.
Four, skin irritation test
The hair of family's rabbit back backbone two sides is removed with depilatory agent, must not be damaged by the healthy rabbits for selecting 3 skin intact Skin.Unhairing range: left and right each about 3 × 3cm2.Compound pilose antler whitening moisturizing face masque high concentration group test specimen is picked with cotton swab It is applied on the unhairing intact skin of rabbit side, is washed away after 4h with warm water;Rabbit other side skin of unhairing is as blank control (smearing physiological saline).It smears once daily, continuously smears 14d.Result is observed for 24 hours after each smear.Test display, 3 None generates redness, inflammation, phenomena such as festering to rabbit skin of back, and test specimen side skin and control sides skin color are without obvious Difference.Prove the compound pilose antler whitening moisturizing face masque stoste to no skin irritation.
The present invention is the strong Radix Angelicae Sinensis of promoting blood circulation whitening function, the root of Dahurain angelica, white by with benefiting essence-blood and the pilose antler extracting solution of function of preserving youthful looks Clear or translucent is made in splendid achnatherum extract, honey and the auxiliary materials such as aloe and moisturizer with antibacterial and moisture-keeping function Liquid, quantitative to be packed into the aluminium foil bag for being placed with silk mask paper, then sealed package.The silk mask paper of facial shape is impregnated in bag Facial mask stoste becomes molding facial mask.
In use, cutting off sealing bags, take out a molding facial mask and be attached to face, it is made to be close to 15- with face 20min, facial mask are gradually absorbed drying, it is easy to be removed.The purpose that can reach cleaning and caring skin and beauty is used for a long time.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (6)

1. a kind of compound pilose antler moisturizing whitening mask suitable for plateau crowd, which is characterized in that the original including following parts by weight Material is made: 5-10 parts of pilose antler, 10-20 parts of aloe, and 10-20 parts of the bletilla striata, 10-20 parts of the root of Dahurain angelica, 20-30 parts of Radix Angelicae Sinensis, honey 20-30 Part, 25-50 parts of glycerol, 20-40 parts of 1,3-BDO, 1-2 parts of hyaluronic acid, 1-2 parts of propylben, distilled water adds to 1000 Part.
2. a kind of compound pilose antler moisturizing whitening mask suitable for plateau crowd as described in claim 1, it is characterised in that: packet The raw material for including following parts by weight is made: 7 parts of pilose antler, 15 parts of aloe, and 15 parts of the bletilla striata, 15 parts of the root of Dahurain angelica, 25 parts of Radix Angelicae Sinensis, 25 parts of honey, 35 parts of glycerol, 30 parts of 1,3 butylene glycol, 1.5 parts of hyaluronic acid, 1.5 parts of propylben, distilled water add to 1000 parts.
3. a kind of preparation method of the compound pilose antler moisturizing whitening mask suitable for plateau crowd as claimed in claim 1 or 2, It is characterized by comprising following steps:
Step A, above-mentioned raw materials are weighed according to parts by weight;
Step B, the extracting solution for extracting pilose antler, aloe, the bletilla striata, the root of Dahurain angelica, Radix Angelicae Sinensis, extracting solution is uniformly mixed;
Step C, in step B mixed liquor be added honey, glycerol, 1,3-BDO, hyaluronic acid, propylben, then plus Distilled water dilutes to obtain compound pilose antler moisturizing whitening mask stoste;
Step D, the stoste in step C is packed into the facial mask bag for being placed with silk mask paper, is sealed up to the moisturizing whitening of compound pilose antler Facial mask.
4. a kind of preparation method of the compound pilose antler moisturizing whitening mask suitable for plateau crowd as claimed in claim 3, It is characterized in that: the preparation of pilose antler extracting solution in the step B: after weighed velvet powder filter paper packaging, being placed in Soxhlet and mention It takes in device, distilled water is added, extract 4h, filtrate is collected in filtering, and filtrate is pilose antler extracting solution.
5. a kind of preparation method of the compound pilose antler moisturizing whitening mask suitable for plateau crowd as claimed in claim 3, Be characterized in that: the preparation of extract solution from aloe in the step B: Chinese aloe leaf is shredded, and is put into blender and is carried out break process, obtains high 10mg alpha-amylase is added in the aloe liquid of viscosity, after being sufficiently stirred, places it in 55 DEG C of constant temperature 4h, 95% ethyl alcohol is added, shakes It is even, in being placed at room temperature for 48h, precipitating is removed, ethyl alcohol is removed under reduced pressure, residue adds distilled water ultrasonic dissolution, and filtering, filtrate is aloe Extracting solution.
6. a kind of preparation method of the compound pilose antler moisturizing whitening mask suitable for plateau crowd as claimed in claim 3, Be characterized in that: the preparation of bletilla striata extract, root of Dahurain angelica extracting solution, angelica extract in the step B: by the weighed bletilla striata, the root of Dahurain angelica, Chinese Angelica Root first uses distilled water circumfluence distillation 2h, reuses distilled water and repeats to extract 1 time, combined extract, and 60 DEG C of decompressions are dense Contracting, dehydrated alcohol is added in concentrate, shakes up, and removes precipitating, and ethyl alcohol is removed under reduced pressure, and residue adds appropriate distilled water ultrasound Dissolution, filtering, filtrate is the extracting solution.
CN201910459886.9A 2019-05-29 2019-05-29 A kind of compound pilose antler moisturizing whitening mask and preparation method thereof suitable for plateau crowd Pending CN110075053A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112451467A (en) * 2020-12-16 2021-03-09 苏州红冠庄国药股份有限公司 Skin care ampoule bottle stock solution containing cornu cervi pantotrichum active substances, preparation method and application
CN112545965A (en) * 2020-12-16 2021-03-26 苏州红冠庄国药股份有限公司 Moisturizing and beautifying facial mask containing pilose antler active substances, preparation method and application
CN115227629A (en) * 2022-09-05 2022-10-25 吉林一瑞生物科技有限公司 Pilose antler moisturizing mask and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112451467A (en) * 2020-12-16 2021-03-09 苏州红冠庄国药股份有限公司 Skin care ampoule bottle stock solution containing cornu cervi pantotrichum active substances, preparation method and application
CN112545965A (en) * 2020-12-16 2021-03-26 苏州红冠庄国药股份有限公司 Moisturizing and beautifying facial mask containing pilose antler active substances, preparation method and application
CN115227629A (en) * 2022-09-05 2022-10-25 吉林一瑞生物科技有限公司 Pilose antler moisturizing mask and preparation method thereof

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