CN107219352A - A kind of reagent strip pusher of chemical illumination immunity analysis instrument - Google Patents
A kind of reagent strip pusher of chemical illumination immunity analysis instrument Download PDFInfo
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- CN107219352A CN107219352A CN201710500299.0A CN201710500299A CN107219352A CN 107219352 A CN107219352 A CN 107219352A CN 201710500299 A CN201710500299 A CN 201710500299A CN 107219352 A CN107219352 A CN 107219352A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
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Abstract
The invention discloses a kind of reagent strip pusher of chemical illumination immunity analysis instrument, including transmission component, coulisse, pusher, bottom plate;Wherein, the transmission component is used to drive pusher, the pusher is under the limitation and guiding of coulisse, for hooking up the reagent strip being located at below the bottom plate, and by the reagent strip, chemically the incubation disk of luminescence immunoassay instrument treats push area, is moved at the darkroom check position of the chemical illumination immunity analysis instrument and separates;As a result of coulisse, under the limitation and guiding of the coulisse, including completing the quick action that hooks up and in time separate of the pusher to reagent strip, so that the push process of whole strip reagent strip just becomes quite easy, and it is simple in construction, with low cost, the medical institutions for being highly suitable for China are popularized.
Description
Technical field
The present invention relates to in-vitro diagnosis and the chemical illumination immunity analysis instrument field used in biomedicine, more particularly to
It is a kind of quickly to hook up and push the pusher of strip reaction cup reagent strip.
Background technology
Chemiluminescence immunoassay technology(CLIA, chemiluminescent immunoassay)It is alive nearly ten years
Develop very fast on-radiation immuno analytical method in the range of boundary, be after Enzyme-multiplied immune technique(EIA), radioimmunoassay technique
(RIA), immunofluorence technic(FIA)A kind of microdetermination technology of the hypersensitivity grown up afterwards.
Instruction system of the chemiluminescence immune assay by the use of chemical or bio-luminescence system as antigen-antibody reaction, so as to
Quantitatively detect antigen or antibody.Chemistry or bioluminescence material be able to can also dissociate directly as antigen or the label of antibody
Form be used for catalyst mark and adjuvant mark antibody or antigen luminescence-producing reaction in.What chemiluminescence reaction was discharged
Free energy excites intermediate, intermediate is returned to ground state from excitation state, and the photon of energy level such as discharges, then through chemo-immunity point
Analyzer is to the measure of photon, so that accurate quantification measured object content.
Automatic chemiluminescence immunoassay technology integrates classical methodology and advanced technology, with sensitivity it is high,
The outstanding advantages such as preci-sion and accuracy is high, reagent stability is good, automaticity is high.
At present, the medical institutions of China can use reaction cup or anti-in automatic chemiluminescence immunoassay
Cup bar is answered to contain sample survey, it is real to reaction cup or reaction cup bar when being pushed to darkroom and carrying out luminous examine
The operation of mechanization is showed, has eliminated artificial transfer operation, improve analysis efficiency, make automatic chemiluminescence immunoassay
Instrument send cup portion, is incubated part, washing part, test section and grades tights fit, turn of the sample survey between each system
Movement passes through journey and is automatically performed.
But, for the chemical illumination immunity analysis instrument of reagent reacting cup into strips, because the reaction cup reagent strip of strip is long
Degree is longer, and the volume for the reagent strip entirety being made up of multiple reaction cups is more larger than the volume of single reaction cup, therefore, to reagent
The delivery device hooked up to darkroom of bar could be improved.
The content of the invention
In order to solve the above technical problems, the present invention provides a kind of reagent strip pusher of chemical illumination immunity analysis instrument,
It quickly can hook up and push strip reaction cup reagent strip.
Technical scheme is as follows:A kind of reagent strip pusher of chemical illumination immunity analysis instrument, including a biography
Dynamic component, a coulisse, a pusher, a bottom plate;Wherein, the transmission component is used to drive pusher, the push
Device is under the limitation and guiding of coulisse, for hooking up the reagent strip being located at below the bottom plate, and by the reagent strip from change
Learn the darkroom check position treated push area, be moved to the chemical illumination immunity analysis instrument of the incubation disk of luminescence immunoassay instrument
Place is simultaneously separated.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:The transmission component include a motor,
One motor mounting plate, a motor drum in-phase, a belt, a synchronizing wheel installing plate and a drive coordination wheel;The motor mounting plate
The two ends of bottom plate are separately fixed at synchronizing wheel installing plate, the motor and motor drum in-phase are located at the two of motor mounting plate respectively
Side and it is co-axially mounted, the drive coordination wheel is arranged on the side of synchronizing wheel installing plate, is located at the same side, institute with motor drum in-phase
State belt to be socketed on motor drum in-phase and drive coordination wheel, under the driving of the motor, driving belt same in motor
Moved between step wheel and drive coordination wheel.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:The coulisse is vertically installed at institute
State between motor mounting plate and synchronizing wheel installing plate, one first wide bar shaped is provided with the top half of the coulisse
Groove, one second bar-shaped trough and an Article 3 shape groove, for limiting and guiding shifting of the pusher under transmission component drive
Dynamic rail mark;First bar-shaped trough is connected with one end of the second bar-shaped trough, the other end and Article 3 of second bar-shaped trough
Shape groove is connected, and second bar-shaped trough is in horizontal straight-line groove, and first bar-shaped trough is in the acclivitous oblique trunking in outside,
The Article 3 shape groove is symmetrical with the axis of vertical second bar-shaped trough with the first bar-shaped trough.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:The pusher includes two hooks
Bar, a shank mounting blocks, a shank pressing plate, a vertical slipper, a vertical slipper guide rail, a vertical slipper guide rail base, a base
Seat connecting plate, a cross sliding clock guide rail base and a roll sleeve group;The roll sleeve group is mounted in the end of shank mounting blocks lateral out, uses
Rolled around in the first bar-shaped trough, the second bar-shaped trough and Article 3 shape groove for being stuck in the coulisse;The cross sliding clock is led
Multiple connecting holes are provided with base of the rail seat, is connected and fixes with the belt in the transmission component via screw;The pedestal
Connecting plate is vertically installed on cross sliding clock guide rail base, and the vertical slipper is fixed on the side wall of pedestal connecting plate, institute
State vertical slipper guide rail card is used to slide up and down on vertical slipper, and the vertical slipper guide rail base is connected to vertical slipper and led
On rail, the shank mounting blocks are fixed on vertical slipper guide rail base, and the upper end of two shanks is connected via shank pressing plate
On shank mounting blocks.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:On the connecting plate of the reagent strip
Two hook and slots are provided with laterally side by side, and the lower end of two shanks is adapted with two hook and slots, for hooking up and discharging the reagent
Bar.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:Adaptation is provided with the bottom plate
A cross sliding clock is fixed with two grooves that two shank lower semisections are passed through, the bottom plate between two grooves, in the water
The bottom of smooth block guide rail base is connected with a cross sliding clock guide rail, is slided for being stuck on the cross sliding clock.
The reagent strip pusher of described chemical illumination immunity analysis instrument, wherein:One is additionally provided with the bottom plate
Optocoupler sensor cluster, is fixed with the chemical illumination immunity analysis instrument described in an optocoupler piece on the side wall of the pedestal connecting plate
Reagent strip pusher, wherein:The roll sleeve group is rolling bearing group.
The reagent strip pusher of a kind of chemical illumination immunity analysis instrument provided by the present invention, as a result of chute
Plate, under the limitation and guiding of the coulisse, including completes pusher quickly hooking up and moving for separating in time to reagent strip
Make so that the push process of whole strip reagent strip just becomes quite easy and simple in construction, with low cost, is especially suitable for
Popularized in the medical institutions of China.
Brief description of the drawings
Fig. 1 is the overall structure stereogram of reagent strip pusher of the present invention.
Fig. 2 is the front view of coulisse used in reagent strip pusher of the present invention.
Fig. 3 is the amplification stereogram for pushing component in reagent strip pusher of the present invention.
Fig. 4 is that reagent strip pusher of the present invention hooks up and pushed schematic diagram.
Embodiment
Below with reference to accompanying drawing, embodiment and embodiment to the present invention are described in detail, described tool
Body embodiment only to explain the present invention, is not intended to limit the embodiment of the present invention.
As shown in figure 1, Fig. 1 is the overall structure stereogram of reagent strip pusher of the present invention, the reagent strip pusher
Slided for chemical illumination immunity analysis instrument, including a transmission component 1, a coulisse 2, a pusher 3, a bottom plate 5, a level
The optocoupler sensor cluster 7 of block 6 and one;Wherein, the optocoupler sensor cluster 7, cross sliding clock 6, coulisse 2 and transmission component
1 is installed on bottom plate 5, and the cross sliding clock 6 does horizontal rectilinear motion in a longitudinal direction for limiting pusher 3,
The optocoupler sensor cluster 7 is used for the final position for sensing pusher 3;The transmission component 1 is used to drive pusher
3, the pusher 3 is located at the reagent strip 4 of the lower section of bottom plate 5 for hooking up under the limitation and guiding of coulisse 2, and
By the reagent strip 4, chemically the incubation disk of luminescence immunoassay instrument treats push area, is moved to the chemiluminescence immune assay
At the darkroom check position of instrument and separate.
In the embodiment of the reagent strip pusher of chemical illumination immunity analysis instrument of the present invention, specifically, institute
Stating transmission component 1 includes a motor 11, a motor mounting plate 12, a motor drum in-phase 13, a belt 14, a synchronizing wheel installing plate
15 and a drive coordination wheel 16;Wherein, the motor mounting plate 12 and synchronizing wheel installing plate 15 are separately fixed at the two of bottom plate 5
End, the motor 11 and motor drum in-phase 13 positioned at the both sides of motor mounting plate 12 and are co-axially mounted, the drive coordination respectively
Wheel 16 is arranged on the side of synchronizing wheel installing plate 15, is located at the same side with motor drum in-phase 13, and the belt 14 is socketed in motor
In synchronizing wheel 13 and drive coordination wheel 16, under the driving of the motor 11, drive belt 14 motor drum in-phase 13 with
Moved between drive coordination wheel 16.
With reference to shown in Fig. 2, Fig. 2 is the front view of coulisse used in reagent strip pusher of the present invention, in chemistry of the invention
In the embodiment of the reagent strip pusher of luminescence immunoassay instrument, specifically, the coulisse 2 is vertically installed at electricity
Between machine installing plate 12 and synchronizing wheel installing plate 15, one first wide bar shaped is provided with the top half of the coulisse 2
Groove 21, one second bar-shaped trough 22 and an Article 3 shape groove 23, for limiting and guiding the pusher 3 in the band of transmission component 1
Motion track under dynamic;Wherein, first bar-shaped trough 21 is connected with one end of the second bar-shaped trough 22, second bar-shaped trough
22 other end is connected with Article 3 shape groove 23, and second bar-shaped trough 22 is in horizontal straight-line groove, first bar-shaped trough
21 be in the acclivitous oblique trunking in outside, and the Article 3 shape groove 23 is with the first bar-shaped trough 21 with vertical second bar-shaped trough 22
Symmetrically, the bar-shaped trough connected by first bar-shaped trough 21, the second bar-shaped trough 22 and Article 3 shape groove 23 is in entirety for axis
Upper is in inverse Ba type or bell-mouthed shape.
With reference to shown in Fig. 3, Fig. 3 is the amplification stereogram for pushing component in reagent strip pusher of the present invention, in this hair
In the embodiment of the reagent strip pusher of bright chemical illumination immunity analysis instrument, specifically, the pusher 3 includes
Two shanks 31, a shank mounting blocks 311, a shank pressing plate 33, a vertical slipper 34, a vertical slipper guide rails 310, one are vertical
Slide block guide rail pedestal 39, a pedestal connecting plate 35, an optocoupler piece 36, a cross sliding clock guide rail 38, a cross sliding clock guide rail base
37 and a roll sleeve group 32;Wherein, the roll sleeve group 32 is mounted in the end of shank mounting blocks 311 lateral out, for being stuck in the cunning
Rolled around in the first bar-shaped trough 21, the second bar-shaped trough 22 and the Article 3 shape groove 23 of frid 2;The cross sliding clock guide rail base
Multiple connecting holes are provided with 37, are connected and fixed with the belt 14 in the transmission component 1 via screw, for passing through skin
Band 14 drives pusher 3 to move back and forth;The cross sliding clock guide rail 38 is connected to the bottom of cross sliding clock guide rail base 37, uses
Slided in being stuck on the cross sliding clock 6;The pedestal connecting plate 35 is vertically installed on cross sliding clock guide rail base 37, institute
State vertical slipper 34 to be fixed on the side wall of pedestal connecting plate 35, the vertical slipper guide rail 310 is stuck on vertical slipper 34 and used
In sliding up and down, the vertical slipper guide rail base 39 is connected on vertical slipper guide rail 310, and the shank mounting blocks 311 are consolidated
It is scheduled on vertical slipper guide rail base 39, the upper end of two shanks 31 is connected to shank mounting blocks 311 via shank pressing plate 33
On, the lower end of two shanks 31 is used to hook up and discharge the reagent strip 4 in Fig. 1;The optocoupler piece 36 is fixed on pedestal connecting plate
It is associated for the optocoupler sensor cluster 7 with being fixed on bottom plate 5 on 35 side wall.
Preferably, two hook and slots 41, two hooks are provided with the connecting plate of strip reagent strip 4 in Fig. 1 laterally side by side
In two hook and slots 41 of the adaptation insertion bar shaped reagent strip of bar 31, for hooking up and discharging the reagent strip 4.
Preferably, on bottom plate 5 in Fig. 1, two grooves has been arranged side by side along the moving direction of pusher 3, have been used for
The lower semisection of shank 31 being adapted to after installation in the pusher 3 is passed through;The cross sliding clock 6 is fixed between two grooves
On bottom plate 5.
Preferably, the roll sleeve group 32 is set to rolling bearing group, it is possible thereby to further reduce pusher 3 in movement
During, when the roll sleeve group 32 is rolled in the first bar-shaped trough 21, the second bar-shaped trough 22 and Article 3 shape groove 23 of coulisse 2
Frictional resistance.
The operation principle of the reagent strip pusher of chemical illumination immunity analysis instrument of the present invention is:Because being pushed away by reagent strip
During being sent to the luminous inspection of darkroom progress, whole operation, which needs to realize, to be automated, therefore in the push process of reagent strip 4
In, by being incubated the fine rotational of disk, reagent strip 4 is rested in and treats push area;Now, the motor 11 of the transmission component 1
Rotate forward and drive the positive movement of belt 14, the roll sleeve group 32 that the driving of belt 14 pushes component 3 is passed through from the first bar-shaped trough 21 of coulisse 2
Second bar-shaped trough 22 moves to Article 3 shape groove 23 so that two shanks 31 do the motion for declining and advancing, and then cause two
In two hook and slots 41 of the hook insertion reagent strip 4 of the lower end of shank 31, the reagent strip 4 treated in push area is triggered, and moves
Darkroom check bit stopping is moved and rises to, the reversion of motor 11 of the transmission component 1 afterwards drives the counter motion of belt 14, belt
The roll sleeve group 32 of 14 driving pushing components 3 is rolled in the Article 3 shape groove 23 of coulisse 2 so that two shanks 31 do and declined simultaneously
The motion of retrogressing, and then the hook of two lower ends of shank 31 is deviate from from two hook and slots 41 of reagent strip 4, to be examined in darkroom
Test position release reagent strip 4.
Specifically, with reference to shown in Fig. 4, Fig. 4 is that reagent strip pusher of the present invention hooks up and pushed schematic diagram, is being pushed
At the beginning of location A, the motor 11 of the transmission component 1 rotates forward (i.e. motor drum in-phase 13 in Fig. 1 is rotated counterclockwise) and drives skin
The positive movement of band 14, under the driving of belt 14, when the roll sleeve group 32 of the pushing component 3 is in the bar-shaped trough 21 of coulisse 2 first
During middle rolling, two shanks 31 decline and moved ahead, and the hook insertion of two lower ends of shank 31 treats that the reagent strip 4 in push area connects
In two hook and slots 41 on fishplate bar, and the incubation disk of chemical illumination immunity analysis instrument is treated that the reagent strip 4 in push area is hooked.
B location among push, when the roll sleeve group 32 of the pushing component 3 is in the bar-shaped trough 22 of coulisse 2 second and
When being rolled in three bar-shaped troughs 23, the hooks of two lower ends of shank 31 hooks the continuation level of reagent strip 4 and moves ahead and rise, and by reagent
Bar 4 pushes away the darkroom check position toward chemical illumination immunity analysis instrument.
Optocoupler piece 36 in the whole location of C of push, the pushing component 3 triggers the optocoupler sensing on the bottom plate 5
Device assembly 7, the motor 11 of the transmission component 1 stops;Afterwards, the motor 11 of the transmission component 1 inverts (i.e. electricity in Fig. 1
Machine synchronizing wheel 13 is rotated clockwise) counter motion of belt 14 is driven, under the driving of belt 14, after two shanks 31 decline simultaneously
Move back, the hook of two lower ends of shank 31 is deviate from from the two of reagent strip 4, two hook and slot 41, and reagent strip 4 is discharged in chemiluminescence
The darkroom check position of immunity analysis instrument, latter two shank 31 continue retreat and rise, it is described push component 3 return location A,
So repeatedly, until receiving the instruction for stopping pushing.
When in use, strip reagent strip is previously positioned at the reagent strip pusher of chemical illumination immunity analysis instrument of the present invention
In the incubation disk of chemical illumination immunity analysis instrument, and reagent strip one end is fixed by buckle, pushed away in the reagent strip from disk is incubated
The process of darkroom inspection is sent to, component is pushed and only needs to move to the 3rd from the first bar-shaped trough on coulisse through the second bar-shaped trough
Bar-shaped trough, it is possible to complete whole push operation, so that the push process of reagent strip becomes quite easy;In addition, reagent
Two slotted eyes that bar is provided with, two hooks one-to-one corresponding with pushing component, when reagent strip is pushed, two hooks are first from examination
The top of agent bar progressively declines, and correspondingly extend into two slotted eyes of reagent strip, reaches dark pushing components drive reagent strip
After the check position of room, two hooks gradually rise out of the two of reagent strip slotted eyes again, and exit two slotted eyes of reagent strip,
The quick of strip reagent strip is achieved in hook up with separating in time.
It should be appreciated that the foregoing is merely illustrative of the preferred embodiments of the present invention, it e insufficient to the limitation present invention's
Technical scheme, for those of ordinary skills, within the spirit and principles in the present invention, can add according to the above description
With increase and decrease, replace, convert or improve, and the technical scheme after all these increases and decreases, replacement, conversion or improvement, it should all belong to this
The protection domain of invention appended claims.
Claims (8)
1. the reagent strip pusher of a kind of chemical illumination immunity analysis instrument, it is characterised in that including a transmission component, a chute
Plate, a pusher, a bottom plate;Wherein, the transmission component is used to drive pusher, and the pusher is in coulisse
Under limitation and guiding, for hooking up the reagent strip being located at below the bottom plate, and by the reagent strip chemically luminescence immunoassay
The incubation disk of instrument treats push area, is moved at the darkroom check position of the chemical illumination immunity analysis instrument and separates.
2. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 1, it is characterised in that:It is described to pass
Dynamic component includes a motor, a motor mounting plate, a motor drum in-phase, a belt, a synchronizing wheel installing plate and a drive coordination
Wheel;Wherein, the motor mounting plate and synchronizing wheel installing plate are separately fixed at the two ends of bottom plate, the motor and motor drum in-phase
It is located at the both sides of motor mounting plate respectively and is co-axially mounted, the drive coordination wheel is arranged on the side of synchronizing wheel installing plate, with
Motor drum in-phase is located at the same side, and the belt is socketed on motor drum in-phase and drive coordination wheel, in the motor
Under driving, belt is driven to be moved between motor drum in-phase and drive coordination wheel.
3. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 2, it is characterised in that:The cunning
Frid is vertically installed between the motor mounting plate and synchronizing wheel installing plate, is provided with the top half of the coulisse
Wide one first bar-shaped trough, one second bar-shaped trough and an Article 3 shape groove, for limiting and guiding the pusher in transmission
Motion track under component drive;Wherein, first bar-shaped trough is connected with one end of the second bar-shaped trough, second bar shaped
The other end of groove is connected with Article 3 shape groove, and second bar-shaped trough is in horizontal straight-line groove, and first bar-shaped trough is in outer
Inclined oblique trunking on the side, the Article 3 shape groove is mutually right with the axis of vertical second bar-shaped trough with the first bar-shaped trough
Claim.
4. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 3, it is characterised in that:It is described to push away
Send device vertically sliding including two shanks, a shank mounting blocks, a shank pressing plate, a vertical slipper, a vertical slipper guide rail, one
Block guide rail base, a pedestal connecting plate, a cross sliding clock guide rail base and a roll sleeve group;Wherein, the horizontal exterior of the roll sleeve group
In the end of shank mounting blocks, the first bar-shaped trough, the second bar-shaped trough and Article 3 shape groove for being stuck in the coulisse
Rollback is moved;Multiple connecting holes are provided with the cross sliding clock guide rail base, via the belt in screw and the transmission component
It is connected and fixes;The pedestal connecting plate is vertically installed on cross sliding clock guide rail base, and the vertical slipper is fixed on
On the side wall of pedestal connecting plate, the vertical slipper guide rail card is used to slide up and down on vertical slipper, and the vertical slipper is led
Base of the rail seat is connected on vertical slipper guide rail, and the shank mounting blocks are fixed on vertical slipper guide rail base, two shanks
Upper end is connected on shank mounting blocks via shank pressing plate.
5. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 4, it is characterised in that:Described
Two hook and slots are provided with the connecting plate of reagent strip laterally side by side, the lower end of two shanks is adapted with two hook and slots, for hook
Take and discharge the reagent strip.
6. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 4, it is characterised in that:Described
It is provided with bottom plate on two grooves that two shank lower semisections of adaptation are passed through, the bottom plate between two grooves and is fixed with a water
Smooth block, is connected with a cross sliding clock guide rail, for being stuck in the cross sliding clock in the bottom of the cross sliding clock guide rail base
Slide.
7. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 4, it is characterised in that:Described
An optocoupler sensor cluster is additionally provided with bottom plate, an optocoupler piece is fixed with the side wall of the pedestal connecting plate.
8. the reagent strip pusher of chemical illumination immunity analysis instrument according to claim 4, it is characterised in that:The rolling
Set group is rolling bearing group.
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CN201710500299.0A CN107219352B (en) | 2017-06-27 | 2017-06-27 | Reagent strip pushing device of chemiluminescence immunoassay analyzer |
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