CN207036854U - A kind of Full-automatic chemiluminescence immunoassay analysis meter - Google Patents
A kind of Full-automatic chemiluminescence immunoassay analysis meter Download PDFInfo
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- CN207036854U CN207036854U CN201721015724.9U CN201721015724U CN207036854U CN 207036854 U CN207036854 U CN 207036854U CN 201721015724 U CN201721015724 U CN 201721015724U CN 207036854 U CN207036854 U CN 207036854U
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Abstract
The utility model discloses a kind of Full-automatic chemiluminescence immunoassay analysis meter, upper plate pin group device, photon detection device and reagent strip pusher are respectively positioned on above upper plate;Corpse or other object for laboratory examination and chemical testing disk device and incubation disk device are respectively positioned on the lower section of upper plate;Darkroom detection means is located at the region adjacent with photon detection device and reagent strip pusher;The corresponding reagent strip for being incubated disk device, which is put at station, on upper plate is provided with a v-notch groove;Puncture needle group device in upper plate pin group device and enhancing liquid pin group device are provided with not only horizontally moveable but also vertically moving double needle configuration, and another needle assemblies in puncture needle group device and enhancing liquid pin group device are stirring needle assemblies;Due to employing rational layout structure according to the station for being incubated disk device, and the use of double needle configuration is combined, not only increase the automaticity of instrument, also make it that the structure of whole instrument is simpler compact;And cost is cheap, the medical institutions for being highly suitable for China are popularized.
Description
Technical field
Chemiluminescence immune assay apparatus field of the in-vitro diagnosis used in biomedicine is the utility model is related to, is especially related to
And be a kind of Full-automatic chemiluminescence immunoassay analysis meter.
Background technology
POCT real-time tests (Point of Care Testing), it is in-vitro diagnosis industry important development side in recent years
To with fastest-rising field.Technology involved by POCT is varied, in brief, can be divided into simple colour developing, enzyme mark,
Immunoassay, optically and electrically biology sensor, Electrochemical Detection, spectrophotometric and biochip etc..
Chemiluminescence immunoassay technology(CLIA, chemiluminescent immunoassay)Be will have it is highly sensitive
The chemical luminescent detecting technology of degree is combined with the immune response of high specific, for clinical labororatory and R&D institution to various
Antigen, haptens, antibody, hormone, virus marker thing, tumor markers, enzyme, aliphatic acid, vitamin and medicine etc. are detected
The technology of analysis, it is worldwide to develop very fast on-radiation immuno analytical method nearly ten years, is after enzyme-linked
Immunological technique(EIA), radioimmunoassay technique(RIA), immunofluorence technic(FIA)A kind of hypersensitivity to grow up afterwards
Microdetermination technology.
Instruction system of the chemiluminescence immune assay by the use of chemical or bio-luminescence system as antigen-antibody reaction, so as to
Quantitatively detect antigen or antibody.Chemistry or bioluminescence material be able to can also dissociate directly as antigen or the label of antibody
Form be used for catalyst mark and adjuvant mark antibody or antigen luminescence-producing reaction in.What chemiluminescence reaction was discharged
Free energy excites intermediate, intermediate is returned to ground state from excitation state, and the photon of energy level such as discharges, then through chemo-immunity point
Analyzer is to the measure of photon, so as to accurate quantification measured object content.
Automatic chemiluminescence immunoassay technology integrates classical methodology and advanced technology, have high sensitivity,
Outstanding advantages of preci-sion and accuracy is high, reagent stability is good, automaticity is high.
But Chinese developed countries develop more maturation in terms of CLIA research and development, and China is near
Develop in terms of CLIA research and development within several years very fast but be still in the stage of starting, still have larger difference with Chinese foreign countries
It is different, nowadays full-automatic instrument of the China about chemiluminescence immune assay substantially also for offshore company monopolize, price all compared with
For costliness, therefore, a kind of Full-automatic chemiluminescence immunoassay analysis meter of independent development has turned into a main trend of China.
Utility model content
In order to solve the above technical problems, the utility model provides a kind of Full-automatic chemiluminescence immunoassay analysis meter, structure letter
Single compact, automaticity is high.
The technical solution of the utility model is as follows:A kind of Full-automatic chemiluminescence immunoassay analysis meter, it is characterised in that including
Corpse or other object for laboratory examination and chemical testing disk device, it is incubated disk device, frame, upper plate, upper plate pin group device, photon detection device, darkroom detection means and reagent
Bar pusher;Wherein:Upper plate is fixed on frame, upper plate pin group device, photon detection device and reagent strip pusher
It is installed on upper plate, and is respectively positioned on the top of upper plate;Corpse or other object for laboratory examination and chemical testing disk device, incubation disk device and darkroom detection means are respectively mounted
On frame, and corpse or other object for laboratory examination and chemical testing disk device and incubation disk device are respectively positioned on the lower section of upper plate;Darkroom detection means is located to be visited with photon
Survey device and the adjacent region of reagent strip pusher;The corresponding reagent strip for being incubated disk device is put at station and set on upper plate
There is a v-notch groove;Upper plate pin group device is by corpse or other object for laboratory examination and chemical testing pin group device, barcode scanning identification device, puncture needle group device, enhancing liquid pin group
Device and cleaning needle group device composition;Wherein, corpse or other object for laboratory examination and chemical testing pin group device is correspondingly arranged at the top of corpse or other object for laboratory examination and chemical testing disk device, barcode scanning identification dress
Put to be correspondingly arranged at and be incubated above the barcode scanning station of disk device, puncture needle group device is correspondingly arranged at the puncture needle for being incubated disk device
Above station, enhancing liquid pin group device, which is correspondingly arranged at, to be incubated above the enhancing liquid pin station of disk device, cleaning needle group device pair
It should be arranged on and be incubated above the cleaning needle station of disk device;It is provided with puncture needle group device and enhancing liquid pin group device and both may be used
Move horizontally and vertically moving double needle configuration, and another needle assemblies in puncture needle group device and enhancing liquid pin group device are equal
To stir needle assemblies.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The double needle configuration is included in horizontally movable one
A belt that can be driven by motor, the stirring needle assemblies and another sample-adding needle assemblies are arranged in vertical in supporting plate
It is connected to not on the belt of homonymy.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The incubation disk device include reagent disc pallet component,
Upper lid, base assembly, upper lower magnet hyte part and reagent disc component;It is wherein, upper to cover the oral area for being fastened on reagent disc pallet component,
Reagent disc component is arranged on reagent disc pallet component and in the inner space of upper lid composition, base assembly is arranged on reagent disk in pallet
The center of component bottom, for controlling reagent disc component fine rotational under the instruction of input;Upper lower magnet hyte part is positioned at examination
The lower section of agent disk component, the corresponding lower section for being arranged on the corpse or other object for laboratory examination and chemical testing pin station for being incubated disk device.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The upper lid is rounded, thereon radially successively by suitable
Hour hands are provided with a U-shaped gap slot, a barcode scanning square groove, a puncture needle bar-shaped trough, an enhancing pin bar-shaped trough, a cleaning needle bar shaped
Groove, reagent push bar-shaped trough and a corpse or other object for laboratory examination and chemical testing pin bar-shaped trough;Wherein, the reagent push bar-shaped trough is two parallel openings
Groove;And it is respectively arranged with the corresponding position of the upper plate and the barcode scanning square groove, puncture needle bar-shaped trough, enhancing pin bar shaped
Groove, cleaning needle bar-shaped trough, reagent push the shape identical function trough of bar-shaped trough and corpse or other object for laboratory examination and chemical testing pin bar-shaped trough;The v-notch groove
It is corresponding with U-shaped gap slot.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The reagent disc component specifically includes an examination of circle
Agent plate rail, a deck connecting plate, a reagent plate rail contiguous block and multiple bar shaped reagent strip decks;Wherein, reagent plate rail contiguous block
It is connected positioned at the center of reagent plate rail, and with the rotary shaft of base assembly, for driving reagent plate rail and deck connecting plate to turn
It is dynamic;The deck connecting plate is enclosed on reagent plate rail contiguous block, and the periphery of the deck connecting plate be radially evenly equipped with it is more
Individual U-type groove, bar shaped reagent strip deck are connected to the end of U-type groove, are used to position push-in between adjacent two bar shapeds reagent strip deck
Single bar shaped reagent strip, in the root of each U-type groove, an Elastic buckle is both provided with, for blocking the single bar shaped of push-in
Reagent strip.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The darkroom detection means includes waste paper box, switch gate
Preceding board component, PMT data acquisition component, outer cover, darkroom supporting plate, magnet hyte part, rail plate component, magnet position or so move
Dynamic component and darkroom bottom plate;Wherein, board component and outer cover are fastened on the darkroom sky that closing is formed on the bottom plate of darkroom before switch gate
Between, it is equal that PMT data acquisition component, darkroom supporting plate, magnet hyte part, rail plate component and magnet position move left and right component
The inside in the darkroom space that board component forms before by darkroom bottom plate, outer cover and switch gate;Darkroom supporting plate is fixed on secretly
On the bottom plate of room, PMT data acquisition component is arranged on the top of darkroom supporting plate, for being in the state of closing in darkroom space
Under, data acquisition is carried out to the test tube in bar shaped reagent strip;Rail plate component and magnet position move left and right component and laterally pacified
Between board component before switch gate and darkroom supporting plate, the foreboard before switch gate in board component is provided with a square through hole chamber,
For the disengaging of magnet hyte part and bar shaped reagent strip, the square via cavities are by a switch door termination moving up and down and open
Darkroom space is opened, and rail plate component is located at the top that magnet position moves left and right component, magnet hyte part is led installed in slip
On rail assembly, in the state of being in opening in darkroom space, the bar shaped reagent strip that pending data gathers is picked up into darkroom
The specified location in space, and the bar shaped reagent strip of data acquisition is pushed out darkroom space;The waste paper box is located at darkroom
The outside in space, and close to the side of board component before the switch gate;For collecting the bar gathered through PMT data acquisition component
Shape reagent strip.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The magnet hyte part includes magnet upper plate, magnet bottom
Plate, left magnetic receiver, right magnetic receiver, magnet, magnet fixed plate, magnet move up and down plate, magnet slide block, magnet slide block guide rail, magnetic
Iron machine, magnet rolling bearing assembly;Wherein:Magnet upper plate is connected on rail plate component, and magnet fixed plate vertically connects
The lower section of magnet upper plate is connected on, magnet electric motor is arranged on magnet fixed plate, and magnet rolling bearing assembly is eccentrically set on magnetic
On the output panel of iron machine, magnet slide block is located on magnet fixed plate and perpendicular with magnet upper plate, and magnet slide block guide rail is fitted
Fit over and slided on magnet slide block, magnet moves up and down plate and is connected on magnet slide block, and moves up and down in magnet and laterally set on plate
A slotted hole is equipped with, the bearing for being adapted in magnet rolling bearing assembly rolls in the slotted hole;The magnet bottom plate is consolidated
The top that magnet moves up and down plate is scheduled on, magnet bottom plate is vertically fixed on side by side embedded with the left magnetic receiver of magnet and right magnetic receiver
On, the top surface of left magnetic receiver and right magnetic receiver is respectively arranged with the boss that adaptation blocks bar shaped reagent strip, on magnet upper plate also
It is arranged side by side and is adapted to the bar hole that left magnetic receiver and right magnetic receiver stretch out, under the driving of magnet electric motor, by magnet electricity
Being converted to for machine moves up and down moving up and down for plate, and with being moved down on the left magnetic receiver on moving magnet bottom plate and right magnetic receiver
It is dynamic, to block and discharge bar shaped reagent strip.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The reagent strip pusher include a transmission component,
One coulisse, a pusher, a bottom plate, a cross sliding clock and an optocoupler sensor cluster;Wherein, optocoupler sensor group
Part, cross sliding clock, coulisse and transmission component are installed on bottom plate, and cross sliding clock is used to limit pusher in longitudinal side
Horizontal rectilinear motion is done upwards, and optocoupler sensor cluster is used for the final position for sensing pusher;Transmission component is used to drive
Pusher, the pusher is under the limitation and guiding of coulisse, for hooking up the bar shaped being located at below bottom plate examination
Agent bar, and by the bar shaped reagent strip, chemically the incubation disk of luminescence immunoassay instrument treats push area, is moved to chemistry hair
At the darkroom check position of light immunity analysis instrument and separate;The top half of the coulisse is provided with one first wide bar shaped
Groove, one second bar-shaped trough and an Article 3 shape groove, for limiting and guiding moving rail of the pusher under transmission component drive
Mark;First bar-shaped trough is connected with one end of the second bar-shaped trough, and the other end of the second bar-shaped trough is connected with Article 3 shape groove, the
Two bar-shaped troughs are in horizontal straight-line groove, and the first bar-shaped trough is in the acclivitous oblique trunking in outside, Article 3 shape groove and the first bar shaped
Groove is symmetrical with the axis of vertical second bar-shaped trough, is connected by the first bar-shaped trough, the second bar-shaped trough with Article 3 shape groove
Bar-shaped trough is in inverse Ba type or bell-mouthed shape on the whole.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:The pusher includes two shanks, a shank is pacified
Fill block, a shank pressing plate, a vertical slipper, a vertical slipper guide rail, a vertical slipper guide rail base, a pedestal connecting plate, one
Optocoupler piece, a cross sliding clock guide rail, a cross sliding clock guide rail base and a roll sleeve group;Wherein, roll sleeve group is mounted in shank lateral out
The end of mounting blocks, rolled around for being stuck in the first bar-shaped trough, the second bar-shaped trough and Article 3 shape groove of coulisse;It is horizontal
Multiple connecting holes are provided with slide block guide rail pedestal, is connected and fixes with the belt in transmission component via screw, for leading to
The belt drive pusher is crossed to move back and forth;Cross sliding clock guide rail is connected to the bottom of cross sliding clock guide rail base, for card
Slided on cross sliding clock;Pedestal connecting plate is vertically installed on cross sliding clock guide rail base, and vertical slipper is fixed on pedestal
In the side wall of connecting plate, vertical slipper guide rail card is used to slide up and down on vertical slipper, and vertical slipper guide rail base is connected to
On vertical slipper guide rail, shank mounting blocks are fixed on vertical slipper guide rail base, and the upper end of two shanks is via shank pressure
Plate is connected on shank mounting blocks, and the lower end of two shanks is used to hook up and discharge bar shaped reagent strip;Optocoupler piece is fixed on pedestal
It is associated for the optocoupler sensor cluster with being fixed on bottom plate in the side wall of connecting plate.
Described Full-automatic chemiluminescence immunoassay analysis meter, wherein:Bar used in the Full-automatic chemiluminescence immunoassay analysis meter
Shape reagent strip includes inclined-plane reagent tube assembly and cylinder reagent tube assembly;Inclined-plane Reagent Tube in the inclined-plane reagent tube assembly is equal
For Beads enrichment test tube, and the tube wall of the Beads enrichment test tube is by the first side wall, test tube bottom, second sidewall, skew wall and the 3rd
Side wall forms, and is formed between the first side wall and second sidewall with test tube bottom and stores liquid zone, skew wall is located at second sidewall and the 3rd side
Between wall, and the inner surface of the skew wall is arc surface.
A kind of Full-automatic chemiluminescence immunoassay analysis meter provided by the utility model, due to according to the work for being incubated disk device
Position employs rational layout structure, and combines the use of double needle configuration, not only increases the automaticity of instrument, also causes
The structure of whole instrument is simpler compact;And cost is cheap, the medical institutions for being highly suitable for China are promoted
And popularization.
Brief description of the drawings
Fig. 1 is the overall structure stereogram of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment;
Fig. 2 is putting for puncture needle group device part used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
Big stereogram;
Fig. 3 is the amplification used for being incubated disk device part of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
Stereogram;
Fig. 4 is the reagent disc components in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 3
Top view;
Fig. 5 is putting for darkroom detection means part used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
Big stereogram;
Fig. 6 is the magnet position components in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 5
Amplification stereogram;
Fig. 7 is the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment agents useful for same bar pusher part
Amplification stereogram;
Fig. 8 is putting for the push components in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 7
Big stereogram;
Fig. 9 is the amplification of single-piece bar shaped reagent strip used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
Stereogram;
Figure 10 is the schematic diagram that the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment carries out Beads enrichment.
Embodiment
Below with reference to accompanying drawing, specific embodiment of the present utility model and embodiment are described in detail, it is described
Specific embodiment only to explain the utility model, be not intended to limit specific embodiment of the present utility model.
As shown in figure 1, Fig. 1 is the overall structure solid of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
Figure, the full-automatic chemical illumination immunity analysis instrument include corpse or other object for laboratory examination and chemical testing disk device 1, are incubated disk device 2, frame 3, upper plate 4, upper plate pin
Group device 5, photon detection device 6, darkroom detection means 7 and reagent strip pusher 8;Wherein, the upper plate 4 is fixed on frame
On 1, upper plate pin group device 5, photon detection device 6 and the reagent strip pusher 8 are installed on upper plate 4, and
Positioned at the top of upper plate 4;The corpse or other object for laboratory examination and chemical testing disk device 1, incubation disk device 2 and darkroom detection means 7 are installed on frame 1,
And corpse or other object for laboratory examination and chemical testing disk device 1 and incubation disk device 2 are respectively positioned on the lower section of upper plate 4;The darkroom detection means 7 is located to be filled with photon detection
Put 6 and the adjacent region of reagent strip pusher 8;And the corresponding reagent strip for being incubated disk device 2 is put into work on the upper plate 4
A v-notch groove 41 is provided with position.
The upper plate pin group puncture needle group device of the utility model Full-automatic chemiluminescence immunoassay analysis meter, the pin assembling of enhancing liquid
Put using there is crosspointer device, can both realize and move horizontally, can realize and vertically move again, stirring action can also be realized,
Realize and complete puncture, the sample-adding of reagent and stirring jointly using same device, can also be reached with equivalent using less pin group
Fruit, so as to which whole instrument is simpler, compact.
Moreover, this be laid out the structure of whole instrument according to the station for being incubated disk device 2, only reagent strip need to be passed through V
Type gap slot 41, which is placed on, to be incubated in disk device 2 and promotes clamping, and whole instrument can, which is realized, to be punctured to reagent strip, added
A series of automation steps such as reagent, stirring, cleaning, incubation and Beads enrichment, the luminous detection in darkroom, the automatic collection of abandoned reagents bar
Suddenly, so as to improving whole chemical illumination immunity analysis instrument automaticity.
The upper plate pin group device 5 is specific again by corpse or other object for laboratory examination and chemical testing pin group device 51, barcode scanning identification device 52, puncture needle group device
53rd, strengthen liquid pin group device 54 and cleaning needle group device 55 forms;Wherein, the corpse or other object for laboratory examination and chemical testing pin group device 51 is correspondingly arranged at a corpse or other object for laboratory examination and chemical testing
The top of disk device 1, barcode scanning identification device 52, which is correspondingly arranged at, to be incubated above the barcode scanning station of disk device 2, puncture needle group device
53 are correspondingly arranged at the puncture needle station top for being incubated disk device 2, and enhancing liquid pin group device 54, which is correspondingly arranged at, is incubated disk device 2
Enhancing liquid pin station above, cleaning needle group device 55, which is correspondingly arranged at, to be incubated above the cleaning needle station of disk device 2;It is described to wear
Not only horizontally moveable but also vertically moving double needle configuration is provided with pricker group device 53 and enhancing liquid pin group device 54, and
Another needle assemblies in the puncture needle group device 53 and enhancing liquid pin group device 54 are stirring needle assemblies.
This way using same device, puncture, the sample-adding of reagent and the function of stirring is realized jointly so that whole
Pin group device used in chemical illumination immunity analysis instrument can be less, so that the structure of whole instrument is simpler compact,
And automaticity is high.
In the embodiment of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment, with puncture needle group
Exemplified by device 53, as shown in Fig. 2 Fig. 2 is puncture needle used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
The amplification stereogram of device part is organized, horse can be passed through by being arranged in vertical one in a horizontally movable supporting plate 530
Up to the belt 533 of driving, sample-adding needle assemblies 531 and the stirring needle assemblies 532 of the puncture needle group device 53 are connected to not
On the belt 533 of homonymy, when being moved down for being loaded needle assemblies 531, stirring needle assemblies 532 move up, and vice versa;
Double needle configuration in the enhancing liquid pin group device 54 is identical with the double needle configuration in puncture needle group device 53, no longer superfluous herein
State.
In the embodiment of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment, with reference to Fig. 3 institutes
Show, Fig. 3 is that the amplification used for being incubated disk device part of the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment is three-dimensional
Figure;The incubation disk device 2 specifically includes reagent disc pallet component 21, upper lid 22, base assembly 23, the upper and of lower magnet hyte part 24
Reagent disc component 25;Wherein, the upper lid 22 is fastened on the oral area of reagent disc pallet component 21, and the reagent disc component 25 is installed
In the inner space of reagent disc pallet component 21 and upper lid 22 composition, the base assembly 23 is arranged on reagent disc pallet component
The center of 21 bottoms, for controlling the fine rotational of reagent disc component 25 under the instruction of input;Operating personnel can be incubated disk dress
2 reagent strip is put to be put at station bar shaped reagent strip 9 is put into reagent disc component 25 and promotes clamping;The upper lower magnet position
Component 24 is located at the lower section of reagent disc component 25, the corresponding lower section for being arranged on the corpse or other object for laboratory examination and chemical testing pin station for being incubated disk device 2.
Specifically, the upper lid 22, its structure is rounded, is disposed radially the slotted eye of multiple different functions thereon, bag
Include successively by be distributed clockwise a U-shaped gap slot 221, a barcode scanning square groove 222, a puncture needle bar-shaped trough 223, one strengthen pin
Bar-shaped trough 224, a cleaning needle bar-shaped trough 225, the reagent push corpse or other object for laboratory examination and chemical testing pin bar-shaped trough 227 of bar-shaped trough 226 and one;Wherein, it is described
Reagent push bar-shaped trough 226 is two parallel open slots;Likewise, the corresponding position of upper plate 4 in Fig. 1, also distinguishes
It is provided with and the barcode scanning square groove 222, puncture needle bar-shaped trough 223, enhancing pin bar-shaped trough 224, cleaning needle bar-shaped trough 225, examination
Agent pushes the shape identical function trough of bar-shaped trough 226 and corpse or other object for laboratory examination and chemical testing pin bar-shaped trough 227, and illustrate only in Fig. 1 and U-shaped lacked with described
The corresponding v-notch groove 41 of mouth groove 221.
With reference to shown in Fig. 4, Fig. 4 is the reagent in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 3
The top view of disk components;The reagent disc component 25 specifically includes a reagent plate rail 253 of circle, a deck connecting plate
251st, a reagent plate rail contiguous block 254 and multiple bar shaped reagent strip decks 252;Wherein, the reagent plate rail contiguous block 254 is located at
The center of reagent plate rail 253, and be connected with the rotary shaft of the base assembly 23 in Fig. 3, for driving reagent plate rail 253 and card
Seat connecting plate 251 rotates;The deck connecting plate 251 is enclosed on reagent plate rail contiguous block 254, and the deck connecting plate 251
Periphery be radially evenly equipped with multiple U-type grooves 255, the bar shaped reagent strip deck 252 is connected to the end of U-type groove 255, phase
It is used for the single bar shaped reagent strip 9 for positioning push-in between adjacent two bar shaped reagent strip decks 252, in the root of each U-type groove 255,
An Elastic buckle is both provided with, for blocking the single bar shaped reagent strip 9 of push-in.
It is preferred that temperature control heating film (not shown) is provided with the inner bottom surface of the reagent plate rail 253, for quick
Heating, and allow the detection environment temperature simulation being incubated in disk device 2 to be suitable with the body temperature of human body;The reagent disc pallet component
21 and upper lid 22 outer wall on be all enclosed with insulation layer assembly (not shown), for being incubated.
With reference to shown in Fig. 5, Fig. 5 is that darkroom used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment is detected
The amplification stereogram of device part;The darkroom detection means 7 specifically includes board component 72, PMT before waste paper box 71, switch gate
(Photomultiplier Tube, photomultiplier) data acquisition components 73, outer cover 74, darkroom supporting plate 75, magnet hyte
Part 76, rail plate component 77, magnet position move left and right component 78 and darkroom bottom plate 79;Wherein, board component before the switch gate
72 and outer cover 74 be fastened on the darkroom space that closing is formed on darkroom bottom plate 79, the PMT data acquisition component 73, darkroom branch
Fagging 75, magnet hyte part 76, rail plate component 77 and magnet position move left and right component 78 be installed in by darkroom bottom plate 79,
The inside in the darkroom space that board component 72 forms before outer cover 74 and switch gate;The darkroom supporting plate 75 is fixed on darkroom bottom plate 79
On, the PMT data acquisition component 73 is arranged on the top of darkroom supporting plate 75, for being in the shape of closing in darkroom space
Under state, data acquisition is carried out to the test tube in bar shaped reagent strip 9;The rail plate component 77 and magnet position move left and right component
78 are transversely mounted on before switch gate between board component 72 and darkroom supporting plate 75, the foreboard before the switch gate in board component 72
A square through hole chamber 726 is provided with, for the disengaging of magnet hyte part 76 and bar shaped reagent strip 9, the square via cavities 726 pass through
One switch door termination moving up and down and unlatching darkroom space, and the rail plate component 77 is located at magnet position and moved left and right
The top of component 78, the magnet hyte part 76 are arranged on rail plate component 77, are opened for being in darkroom space
In the state of, the bar shaped reagent strip 9 that pending data gathers is picked up into the specified location into darkroom space, and by data acquisition
Bar shaped reagent strip 9 is pushed out darkroom space;The waste paper box 71 is located at the outside in darkroom space, and close to the switch gate foreboard
The side of component 72;For collecting the bar shaped reagent strip 9 gathered through PMT data acquisition component 73.
With reference to shown in Fig. 6, Fig. 6 is the magnet in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 5
The amplification stereogram of position components, further, the magnet hyte part 76 specifically includes magnet upper plate 766, magnet bottom plate
762nd, left magnetic receiver 761, right magnetic receiver 763, magnet 764, magnet fixed plate 7611, magnet move up and down plate 7612, magnet is slided
Block 765, magnet slide block guide rail 7616, magnet electric motor 767, magnet rolling bearing assembly 7613;Wherein:The magnet upper plate 766
On the rail plate component 77 of connection in Figure 5, the magnet fixed plate 7611 is vertically connected under magnet upper plate 766
Side, the magnet electric motor 767 are arranged on magnet fixed plate 7611, and the magnet rolling bearing assembly 7613 is eccentrically set on
On the output panel of magnet electric motor 767, the magnet slide block 765 be located on magnet fixed plate 7611 and with the phase of magnet upper plate 766
Vertically, the magnet slide block guide rail 7616, which is fitted on magnet slide block 765, slides, and the magnet moves up and down plate 7612 and is connected to
On magnet slide block 765, and moved up and down in the magnet and a slotted hole 7614 is horizontally arranged with plate 7612, for being adapted to magnet rolling
Bearing in moving axis bearing assembly 7613 rolls in the slotted hole 7614;The magnet bottom plate 762 is fixed on magnet and moved up and down
The top of plate 7612, left magnetic receiver 761 and right magnetic receiver 763 embedded with the magnet 764 are vertically fixed on magnet bottom side by side
On plate 762, the top surface of the left magnetic receiver 761 and right magnetic receiver 763 is respectively arranged with the bar shaped reagent strip for being adapted to and blocking in Fig. 5
9 boss (7621 and 7632), has also been arranged side by side the left magnetic receiver 761 of adaptation on magnet upper plate 766 and right magnetic receiver 763 is stretched
The bar hole (7661 and 7662) gone out, under the driving of magnet electric motor 767, the magnet rolling bearing assembly of eccentric setting
7613 are rolled in the slotted hole 7614 laterally set, and being converted to for magnet electric motor 767 is moved up and down into the upper of plate 7612
Lower movement, and moved up and down with the left magnetic receiver 761 on moving magnet bottom plate 762 and right magnetic receiver 763, to block and discharge Fig. 5
In bar shaped reagent strip 9.
It is preferred that being fixed with magnet optocoupler connecting plate 769 in the magnet fixed plate 7611, connect in the magnet optocoupler
The upper and lower ends of fishplate bar 769 are respectively arranged with magnet optocoupler sensor cluster 7610 under optocoupler sensor cluster 768 and magnet,
A magnet optocoupler piece 7615 is additionally provided with plate 7612 is moved up and down, and under optocoupler sensor cluster 768 and magnet on magnet
Optocoupler sensor cluster 7610 is associated, the position moved up and down for sensing left magnetic receiver 761 and right magnetic receiver 763.In Fig. 6
The magnet 764 on right magnetic receiver 763 is illustrate only, identical magnet is equally also installed on left magnetic receiver 761, it is left
Magnetic receiver 761, which blocks, to be not shown.
With reference to shown in Fig. 7, Fig. 7 is that the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment agents useful for same bar pushes away
Send the amplification stereogram of device part;Further, the reagent strip pusher 8 specifically includes a transmission component 81, one cunning
Frid 82, a pusher 83, a bottom plate 85, a cross sliding clock 86 and an optocoupler sensor cluster 87;Wherein, the optocoupler
Sensor cluster 87, cross sliding clock 86, coulisse 82 and transmission component 81 are installed on bottom plate 85, the cross sliding clock 86
Horizontal rectilinear motion is done in a longitudinal direction for limiting pusher 83, and the optocoupler sensor cluster 87, which is used to sense, to be pushed
The final position of device 83;The transmission component 81 is used to drive pusher 83, and the pusher 83 is in coulisse 82
Under limitation and guiding, the bar shaped reagent strip 9 of the lower section of bottom plate 85 is located at for hooking up, and by the bar shaped reagent strip 9 chemically
The incubation disk of luminescence immunoassay instrument treats push area, is moved at the darkroom check position of the chemical illumination immunity analysis instrument
And separate.
It is preferred that the coulisse 82 is vertically installed at motor mounting plate and synchronizing wheel installing plate in transmission component 81
Between, the top half of the coulisse 82 is provided with one first wide bar-shaped trough 821, one second bar-shaped trough 822 and one
Article 3 shape groove 823, for limiting and guiding motion track of the pusher 83 under the drive of transmission component 81;Wherein,
First bar-shaped trough 821 is connected with one end of the second bar-shaped trough 822, the other end and the 3rd of second bar-shaped trough 822
Bar-shaped trough 823 is connected, and second bar-shaped trough 822 is in horizontal straight-line groove, and first bar-shaped trough 821 is in incline on the side outside
Oblique oblique trunking, the Article 3 shape groove 823 are mutually right with the axis of vertical second bar-shaped trough 822 with the first bar-shaped trough 821
Claim, the bar-shaped trough connected by first bar-shaped trough 821, the second bar-shaped trough 822 and Article 3 shape groove 823 is on the whole in eight
Font or bell-mouthed shape.
With reference to shown in Fig. 8, Fig. 8 is the push in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment Fig. 7
The amplification stereogram of components;Further, the pusher 83 specifically includes two shanks 831, a shank mounting blocks
8311st, a shank pressing plate 833, a vertical slipper 834, a vertical slipper guide rail 8310, a vertical slipper guide rail base 839, one
Pedestal connecting plate 835, an optocoupler piece 836, a cross sliding clock guide rail 838, a cross sliding clock guide rail base 837 and a roll sleeve group
832;Wherein, the roll sleeve group 832 is mounted in the end of shank mounting blocks 8311 lateral out, for being stuck in Fig. 7 coulisse
Rolled around in 82 the first bar-shaped trough 821, the second bar-shaped trough 822 and Article 3 shape groove 823;The cross sliding clock guide rail base
Multiple connecting holes are provided with 837, is connected and fixes with the belt in transmission component described in Fig. 7 81 via screw, for leading to
The belt drive pusher 83 is crossed to move back and forth;The cross sliding clock guide rail 838 is connected to cross sliding clock guide rail base 837
Bottom, slided for being stuck on the cross sliding clock 86;The pedestal connecting plate 835 is vertically installed at cross sliding clock guide rail base
On 837, the vertical slipper 834 is fixed in the side wall of pedestal connecting plate 835, and the vertical slipper guide rail 8310 is stuck in vertical
It is used to slide up and down on straight sliding block 834, the vertical slipper guide rail base 839 is connected on vertical slipper guide rail 8310, described
Shank mounting blocks 8311 are fixed on vertical slipper guide rail base 839, and the upper end of two shanks 831 is via shank pressing plate 833
It is connected on shank mounting blocks 8311, the lower end of two shanks 831 is used to hook up and discharge the reagent strip 49 in Fig. 7;The light
Coupling piece 836 is fixed in the side wall of pedestal connecting plate 835, for the optocoupler sensor cluster with being fixed in Fig. 7 on bottom plate 85
87 is associated.
Preferably, on bottom plate 85 in the figure 7, two has been arranged side by side along the moving direction of the pusher 83 and has been led to
Groove, the lower semisection of shank 831 for being adapted to after installation in the pusher 83 pass through;The cross sliding clock 86 is fixed on two and led to
On bottom plate 85 between groove.
Preferably, roll sleeve group described in Fig. 8 832 is arranged to rolling bearing group, it is possible thereby to further reduce pusher
83 in moving process, first bar-shaped trough 821, second bar-shaped trough 822 and Article 3 shape of the roll sleeve group 832 in coulisse 82
Frictional resistance when being rolled in groove 823.
With reference to shown in Fig. 9, Fig. 9 is single-piece bar shaped used in the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment
The amplification stereogram of reagent strip;Bar shaped reagent used in the utility model Full-automatic chemiluminescence immunoassay analysis meter above-described embodiment
Bar 9 includes inclined-plane reagent tube assembly 91, cylinder reagent tube assembly 92 and connecting plate 93, the inclined-plane reagent tube assembly 91 and cylinder
Reagent tube assembly 92 is integrally attached on connecting plate 93, and two rectangle necks 94 have been arranged side by side on the connecting plate 93, with
Two shanks 831 in Fig. 8 are adapted, for hooking up and discharging bar shaped reagent strip 9.It is this to use bar shaped reagent strip loaded reagent
The way of reactant so that single Reagent Tube singly need not be put into the incubation disk hole of equipment loading reaction cup during test
In, therefore it is greatly enhanced the operating efficiency and installation quality of detection.
Specifically, the inclined-plane reagent tube assembly 91 is tried by the first inclined-plane Reagent Tube 911, the second inclined-plane successively from outside to inside
Agent pipe 912, the 3rd inclined-plane Reagent Tube 913, the 4th inclined-plane Reagent Tube 914, the 5th inclined-plane Reagent Tube 915 and the 6th inclined-plane Reagent Tube
916 compositions, the inclined-plane of adjacent two inclined-plane Reagent Tube is symmetrically set;Specifically, first inclined-plane Reagent Tube 911 and second
Inclined-plane Reagent Tube 912 is sample Reagent Tube, and the 3rd inclined-plane Reagent Tube 913 and the 4th inclined-plane Reagent Tube 914 are Quality Control
Product Reagent Tube, the 5th inclined-plane Reagent Tube 915 are background Reagent Tube, and the 6th inclined-plane Reagent Tube 916 dilutes for quality-control product
Liquid Reagent Tube.This way using dual retrial pipe, i.e. the first slant tube and the second slant tube are sample Reagent Tube,
3rd slant tube and the 4th slant tube are quality-control product Reagent Tube, thus can realize double shield when examining,
Improve overall testing accuracy so that detection method is more accurate, efficient.
Specifically, the cylinder reagent tube assembly 92 is tried by the first cylinder Reagent Tube 921, the second cylinder successively from inside to outside
Agent pipe 922, the 3rd cylinder Reagent Tube 923, the 4th cylinder Reagent Tube 924, the 5th cylinder Reagent Tube 925 and the 6th cylinder test tube
926 compositions, and the first cylinder Reagent Tube 921 uses Detachable connection structure;Specifically, the first cylinder Reagent Tube
921 be mark Reagent Tube, and the second cylinder Reagent Tube 922 is mark diluent reagent pipe, the 3rd cylinder reagent
Pipe 923 is internal standard Reagent Tube, and the 4th cylinder Reagent Tube 924 is nertralizer Reagent Tube, the He of the 5th cylinder Reagent Tube 925
6th cylinder Reagent Tube 926 is enhancing liquid Reagent Tube.
With reference to shown in Figure 10, Figure 10 is that the utility model Full-automatic chemiluminescence immunoassay analysis meter embodiment carries out magnetic bead point
From schematic diagram;Further, six inclined-plane Reagent Tubes (911 ~ 916) in the inclined-plane reagent tube assembly 91 are magnetic bead point
From test tube, by taking the first inclined-plane Reagent Tube 911 in Fig. 9 as an example, (a) in Figure 10 is the state before Beads enrichment, and (b) is magnetic bead
State after separation, the tube wall of the first Beads enrichment test tube 911 is specifically by the first side wall 9111, test tube bottom 9112, second
Side wall 9113, skew wall 9114 and the 3rd side wall 9116 form, between the first side wall 9111 and second sidewall 9113 with test tube
Bottom 9112, which is formed, stores liquid zone, and the skew wall 9114 is located between the side wall 9116 of second sidewall 9113 and the 3rd, and the skew wall
9114 inner surface is arc surface 9115, and thus the adsorbable surface area of magnetic bead is bigger, to reduce turnover rate, increases operation rate;
It was found from (a) in Figure 10, before Beads enrichment, the magnetic bead in the first inclined-plane Reagent Tube 911 is respectively positioned on storage liquid zone, and from figure
(b) in 10 is understood, when the magnet 9118 being incubated in disk device 2 is close to the first inclined-plane Reagent Tube 911, the magnetic bead 9117 in it
It is split into respectively on the first side wall 9111, second sidewall 9113 and skew wall 9114, to meet the requirement tested and analyzed.Tradition
Chemiluminescence immunoassay technology in Beads enrichment, can only utilize magnet adsorption straight-tube shape test tube wall both sides magnetic bead,
And due to the finite surface area of straight-tube shape test tube both sides, the loss of magnetic bead thus can be caused in magnetic bead flushing process;But this practicality
The region of the new adsorbable magnetic bead of magnetic bead separation test tube is the arc surface of the first side wall, second sidewall and skew wall, so as to carry significantly
The surface area of absorption magnetic bead and the utilization rate of magnetic bead are risen.
The operation principle of the utility model Full-automatic chemiluminescence immunoassay analysis meter and detecting step approximately as:
Step S110, bar shaped reagent strip 9 is placed on and be incubated at the U-shaped gap slot 221 of disk device, and promote clamping, passed through
After the barcode scanning of overscan code recognition device 52 confirms, the puncture for carrying out test tube film in puncture needle group device 53 to bar shaped reagent strip 9 is moved
Make, puncture needle group device 53 is completed to clean after puncturing in service sink;
Step S120, corpse or other object for laboratory examination and chemical testing pin group device 51 adds the mark dilution of the second cylinder test tube 922 of bar shaped reagent strip 9
It is added in the mark of the first cylinder test tube 921, and stirring is completed at puncture needle group device 53;
Step S130, corpse or other object for laboratory examination and chemical testing pin group device 51 adds the nertralizer of the 4th cylinder test tube 924 of bar shaped reagent strip 9 respectively
Tried to the first slant tube 911, the second slant tube 912, the 3rd slant tube 913, the 4th slant tube 914 and the 5th inclined-plane
In pipe 915, and stirring is completed at puncture needle group device 53;
What step S140, a corpse or other object for laboratory examination and chemical testing for corpse or other object for laboratory examination and chemical testing disk device 1 was added separately to bar shaped reagent strip 9 by corpse or other object for laboratory examination and chemical testing pin group device 51 is first oblique
Interview in the slant tube 912 of pipe 911 and second, and stirring action is completed at puncture needle group device 53;
Step S150, after being incubated the incubation a period of time of disk device 2, corpse or other object for laboratory examination and chemical testing pin group device 51 draws first respectively
Inclined-plane Reagent Tube 911, the second inclined-plane Reagent Tube 912, the 3rd inclined-plane Reagent Tube 913, the 4th inclined-plane Reagent Tube 914 and the 5th inclined-plane
Reaction liquid in Reagent Tube 915, and be discharged on the inclined-plane of respective inclined-plane Reagent Tube, by the action repeated several times;Now,
The upper lower magnet hyte part 24 for being incubated disk device 2 moves up, and completes the Beads enrichment of inclined-plane Reagent Tube;Cleaning needle group device 55 afterwards
Respectively to being attached to the first inclined-plane Reagent Tube 911, the second inclined-plane Reagent Tube 912, the 3rd inclined-plane Reagent Tube 913, the 4th inclined-plane reagent
The magnetic bead of pipe 914 and the skew wall of the 5th inclined-plane Reagent Tube 915 is cleaned, and the waste liquid after cleaning is inhaled by cleaning needle group device 55
Walk;Now upper lower magnet hyte part 24 remains in that motionless, after repeated several times cleaning, when last time is cleaned on lower magnet
Hyte part 24 moves down, and liquid to be cleaned washes away adherent magnetic bead, is flushed in the bottom of inclined-plane Reagent Tube, upper lower magnet hyte part 24
Move up again, and waste liquid is siphoned away by cleaning needle group device 55;
Step S160, corpse or other object for laboratory examination and chemical testing pin group device 51 draws the mark in the first cylinder test tube 921 of bar shaped reagent strip 9, point
The first inclined-plane Reagent Tube 911, the second inclined-plane Reagent Tube 912, the 3rd inclined-plane Reagent Tube 913, the 4th inclined-plane Reagent Tube are not loaded onto
914 and the pipe of the 5th inclined-plane reagent 915 in, and at puncture needle group device 53 complete stirring, then be incubated disk device 2 complete incubate
Operation is educated, repeats the above steps 150;
Step S170, the enhancing liquid in the 5th cylinder test tube 925 of the absorption bar shaped of liquid pin group device 54 reagent strip 9 is strengthened,
The first inclined-plane Reagent Tube 911, the second inclined-plane Reagent Tube 912, the 3rd inclined-plane Reagent Tube 913, the 4th inclined-plane reagent are loaded onto respectively
In the inclined-plane Reagent Tube 915 of pipe 914 and the 5th, and after completion stirring at puncture needle group device 53, by the reagent of incubation disk device 2
Bar shaped reagent strip 9 is rested on reagent strip push area by disk component 25, waits reagent strip push component 8 to push;
Step S180, now board component 72 opens the door in darkroom before switch gate, and magnet hyte part 76 is stretched out behind darkroom simultaneously
Move up, stop after Fig. 6 left magnetic receiver 761 and right magnetic receiver 763 stretches out the sub-fraction of magnet upper plate 766, by Fig. 8's
The roll sleeve group 832 of reagent strip push component 8 moves to from the first bar-shaped trough 821 of Fig. 7 coulisse 82 through the second bar-shaped trough 822
Article 3 shape groove 823 so that two shanks 831 do the motion for declining and advancing, and then cause two shanks 831 to insert bar shaped examination
In two hook and slots 93 of agent bar 9, the bar shaped reagent strip 9 treated in push area is caught on, and bar shaped reagent strip 9 is placed on figure
Between 6 left magnetic receiver 761 and right magnetic receiver 763;
Step S190, the left magnetic receiver 761 of magnet hyte part 76 moves up with right magnet 763, treats the boss of magnetic receiver
After (7621 and 7632) block the groove 93 of bar shaped reagent strip, magnet hyte part 76 is returned inside darkroom, and is gathered in PMT data
The lower section of component 73 stops;Now board component 72 is closed before switch gate so that whole darkroom is in closed state;
Step S200, PMT data acquisition component 73 completes light-emitting data collection, and bar shaped reagent strip 9 is by magnet hyte part 76
Dropped automatically in waste paper box 71 after stretching out darkroom.
The utility model Full-automatic chemiluminescence immunoassay analysis meter only needs bar shaped reagent strip being placed in detection incubates
Educate the U-shaped indentation, there of disk device and promote clamping, whole instrument can realize reagent strip is punctured, reagent adding, stirring,
Cleaning, incubation and Beads enrichment, the luminous detection in darkroom, a series of abandoned reagents bar automation steps such as collection, therefore whole automatically
Individual chemical illumination immunity analysis instrument automaticity is higher.
It should be appreciated that the foregoing is only preferred embodiment of the present utility model, it e insufficient to limit this reality
With new technical scheme, for those of ordinary skills, within the spirit and principles of the utility model, Ke Yigen
Increased and decreased according to described above, replaced, converted or improved, and the technical side after all these increases and decreases, replacement, conversion or improvement
Case, it should all belong to the protection domain of the appended claims for the utility model.
Claims (10)
- A kind of 1. Full-automatic chemiluminescence immunoassay analysis meter, it is characterised in that including corpse or other object for laboratory examination and chemical testing disk device, be incubated disk device, frame, Upper plate, upper plate pin group device, photon detection device, darkroom detection means and reagent strip pusher;Wherein:The upper plate is fixed on frame, and upper plate pin group device, photon detection device and reagent strip pusher are installed in On upper plate, and it is respectively positioned on the top of upper plate;The corpse or other object for laboratory examination and chemical testing disk device, it is incubated disk device and darkroom detection means and is installed on frame, and corpse or other object for laboratory examination and chemical testing disk device and incubates Educate the lower section that disk device is respectively positioned on upper plate;The darkroom detection means is located at the region adjacent with photon detection device and reagent strip pusher;The corresponding reagent strip for being incubated disk device, which is put at station, on the upper plate is provided with a v-notch groove;The upper plate pin group device by corpse or other object for laboratory examination and chemical testing pin group device, barcode scanning identification device, puncture needle group device, enhancing liquid pin group device and Cleaning needle group device forms;Wherein, corpse or other object for laboratory examination and chemical testing pin group device is correspondingly arranged at the top of corpse or other object for laboratory examination and chemical testing disk device, and barcode scanning identification device is corresponding It is arranged on and is incubated above the barcode scanning station of disk device, puncture needle group device, which is correspondingly arranged at, is incubated on the puncture needle station of disk device Side, enhancing liquid pin group device, which is correspondingly arranged at, to be incubated above the enhancing liquid pin station of disk device, and cleaning needle group device is correspondingly arranged It is being incubated above the cleaning needle station of disk device;It is provided with puncture needle group device and enhancing liquid pin group device and horizontal can both moves Dynamic and vertically moving double needle configuration, and another needle assemblies in puncture needle group device and enhancing liquid pin group device are stirring Needle assemblies.
- 2. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, it is characterised in that:The double needle configuration includes A belt that can be driven by motor, the stirring needle assemblies are arranged in vertical in a horizontally movable supporting plate It is connected to not on the belt of homonymy with another sample-adding needle assemblies.
- 3. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, it is characterised in that:The incubation Pan Zhuanzhibao Include reagent disc pallet component, upper lid, base assembly, upper lower magnet hyte part and reagent disc component;Wherein, upper lid is fastened on reagent The oral area of disk in pallet component, reagent disc component are arranged in the inner space that reagent disc pallet component forms with upper lid, base group Part is arranged on the center of reagent disc pallet component bottom, for controlling reagent disc component fine rotational under the instruction of input;On Lower magnet hyte part is located at the lower section of reagent disc component, the corresponding lower section for being arranged on the corpse or other object for laboratory examination and chemical testing pin station for being incubated disk device.
- 4. Full-automatic chemiluminescence immunoassay analysis meter according to claim 3, it is characterised in that:The upper lid is rounded, Radially it is provided with a U-shaped gap slot, a barcode scanning square groove, a puncture needle bar-shaped trough, an enhancing pin by clockwise successively thereon Bar-shaped trough, a cleaning needle bar-shaped trough, reagent push bar-shaped trough and a corpse or other object for laboratory examination and chemical testing pin bar-shaped trough;Wherein, the reagent push bar shaped Groove is two parallel open slots;And it is respectively arranged with the corresponding position of the upper plate and the barcode scanning square groove, puncture Pin bar-shaped trough, enhancing pin bar-shaped trough, cleaning needle bar-shaped trough, reagent push the shape identical work(of bar-shaped trough and corpse or other object for laboratory examination and chemical testing pin bar-shaped trough Can groove;The v-notch groove is corresponding with U-shaped gap slot.
- 5. Full-automatic chemiluminescence immunoassay analysis meter according to claim 4, it is characterised in that:The reagent disc component tool Body includes circular a reagent plate rail, a deck connecting plate, a reagent plate rail contiguous block and multiple bar shaped reagent strip decks;Its In, reagent plate rail contiguous block is located at the center of reagent plate rail, and is connected with the rotary shaft of base assembly, for driving reagent disc Frame and deck connecting plate rotate;The deck connecting plate is enclosed on reagent plate rail contiguous block, and the periphery of the deck connecting plate Multiple U-type grooves are radially evenly equipped with, bar shaped reagent strip deck is connected to the end of U-type groove, adjacent two bar shapeds reagent strip deck Between be used for position push-in single bar shaped reagent strip, in the root of each U-type groove, an Elastic buckle is both provided with, for card The single bar shaped reagent strip being firmly pushed into.
- 6. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, it is characterised in that:The darkroom detection means Including board component, PMT data acquisition component, outer cover, darkroom supporting plate, magnet hyte part, rail plate before waste paper box, switch gate Component, magnet position move left and right component and darkroom bottom plate;Wherein, board component and outer cover are fastened on the bottom plate of darkroom before switch gate Form the darkroom space of closing, PMT data acquisition component, darkroom supporting plate, magnet hyte part, rail plate component and magnet Position moves left and right the inside that component is installed in the darkroom space being made up of board component before darkroom bottom plate, outer cover and switch gate;Secretly Room supporting plate is fixed on the bottom plate of darkroom, and PMT data acquisition component is arranged on the top of darkroom supporting plate, for empty in darkroom Between in closing in the state of, in bar shaped reagent strip test tube carry out data acquisition;Rail plate component and magnet position or so Moving assembly is transversely mounted on before switch gate between board component and darkroom supporting plate, and the foreboard before switch gate in board component is set There is a square through hole chamber, for the disengaging of magnet hyte part and bar shaped reagent strip, the square via cavities can move up and down by one Switch door termination and open darkroom space, and rail plate component is located at the top that magnet position moves left and right component, magnet position Component is arranged on rail plate component, in the state of being in opening in darkroom space, by the bar shaped of pending data collection Reagent strip picks up the specified location into darkroom space, and the bar shaped reagent strip of data acquisition is pushed out into darkroom space;Institute The outside that waste paper box is located at darkroom space is stated, and close to the side of board component before the switch gate;Adopted for collecting through PMT data The bar shaped reagent strip that collection component gathered.
- 7. Full-automatic chemiluminescence immunoassay analysis meter according to claim 6, it is characterised in that:The magnet hyte part bag Include magnet upper plate, magnet bottom plate, left magnetic receiver, right magnetic receiver, magnet, magnet fixed plate, magnet and move up and down plate, magnet cunning Block, magnet slide block guide rail, magnet electric motor, magnet rolling bearing assembly;Wherein:Magnet upper plate be connected to rail plate component it On, magnet fixed plate is vertically connected on the lower section of magnet upper plate, and magnet electric motor is arranged on magnet fixed plate, the magnet axis of rolling Bearing assembly is eccentrically set on the output panel of magnet electric motor, and magnet slide block is located on magnet fixed plate and mutually hung down with magnet upper plate Directly, magnet slide block guide rail is fitted on magnet slide block and slided, and magnet moves up and down plate and is connected on magnet slide block, and on magnet A slotted hole is horizontally arranged with lower shifting board, the bearing for being adapted in magnet rolling bearing assembly rolls in the slotted hole It is dynamic;The magnet bottom plate is fixed on the top that magnet moves up and down plate, embedded with the left magnetic receiver of magnet and right magnetic receiver side by side It is vertically fixed on magnet bottom plate, the top surface of left magnetic receiver and right magnetic receiver is respectively arranged with adaptation and blocks the convex of bar shaped reagent strip Platform, the bar hole for being adapted to that left magnetic receiver and right magnetic receiver stretch out also is arranged side by side on magnet upper plate, in magnet electric motor Driving under, being converted to for magnet electric motor is moved up and down into moving up and down for plate, and with the left magnet on moving magnet bottom plate Seat and right magnetic receiver move up and down, to block and discharge bar shaped reagent strip.
- 8. Full-automatic chemiluminescence immunoassay analysis meter according to claim 1, it is characterised in that:The reagent strip push dress Put including a transmission component, a coulisse, a pusher, a bottom plate, a cross sliding clock and an optocoupler sensor cluster;Its In, optocoupler sensor cluster, cross sliding clock, coulisse and transmission component are installed on bottom plate, and cross sliding clock is used to limit Pusher does horizontal rectilinear motion in a longitudinal direction, and optocoupler sensor cluster is used for the final position for sensing pusher; Transmission component is used to drive pusher, and the pusher is under the limitation and guiding of coulisse, for hooking up positioned at described Bar shaped reagent strip below bottom plate, and by the bar shaped reagent strip chemically luminescence immunoassay instrument incubation disk area to be pushed Domain, it is moved at the darkroom check position of the chemical illumination immunity analysis instrument and separates;The top half of the coulisse is set There are one first wide bar-shaped trough, one second bar-shaped trough and an Article 3 shape groove, for limiting and guiding pusher being driven Motion track under component drive;First bar-shaped trough is connected with one end of the second bar-shaped trough, the other end of the second bar-shaped trough with Article 3 shape groove is connected, and the second bar-shaped trough is in horizontal straight-line groove, and the first bar-shaped trough is in the acclivitous oblique trunking in outside, the Three bar-shaped troughs are symmetrical with the axis of vertical second bar-shaped trough with the first bar-shaped trough, by the first bar-shaped trough, the second bar-shaped trough The bar-shaped trough connected with Article 3 shape groove is in inverse Ba type or bell-mouthed shape on the whole.
- 9. Full-automatic chemiluminescence immunoassay analysis meter according to claim 8, it is characterised in that:The pusher includes Two shanks, a shank mounting blocks, a shank pressing plate, a vertical slipper, a vertical slipper guide rail, a vertical slipper guide rail base Seat, a pedestal connecting plate, an optocoupler piece, a cross sliding clock guide rail, a cross sliding clock guide rail base and a roll sleeve group;Wherein, roll Set group is mounted in the end of shank mounting blocks lateral out, for being stuck in the first bar-shaped trough, the second bar-shaped trough and Article 3 of coulisse Rolled around in shape groove;Multiple connecting holes are provided with cross sliding clock guide rail base, via the belt in screw and transmission component It is connected and fixes, moves back and forth for the pusher by belt drive;Cross sliding clock guide rail is connected to cross sliding clock and led The bottom of base of the rail seat, slided for being stuck on cross sliding clock;Pedestal connecting plate is vertically installed on cross sliding clock guide rail base, Vertical slipper is fixed in the side wall of pedestal connecting plate, and vertical slipper guide rail card is used to slide up and down on vertical slipper, vertically Slide block guide rail pedestal is connected on vertical slipper guide rail, and shank mounting blocks are fixed on vertical slipper guide rail base, two shanks Upper end be connected to via shank pressing plate on shank mounting blocks, the lower ends of two shanks is used to hook up and discharge bar shaped reagent Bar;Optocoupler piece is fixed in the side wall of pedestal connecting plate, associated for the optocoupler sensor cluster with being fixed on bottom plate.
- 10. according to any described Full-automatic chemiluminescence immunoassay analysis meter in claim 1 to 9, it is characterised in that:This is complete certainly Bar shaped reagent strip used in dynamic chemical illumination immunity analysis instrument includes inclined-plane reagent tube assembly and cylinder reagent tube assembly;The inclined-plane Inclined-plane Reagent Tube in reagent tube assembly is Beads enrichment test tube, and the tube wall of the Beads enrichment test tube is by the first side wall, examination Bottom of the tube, second sidewall, skew wall and the 3rd side wall form, and are formed between the first side wall and second sidewall with test tube bottom and store liquid Area, skew wall is between second sidewall and the 3rd side wall, and the inner surface of the skew wall is arc surface.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109164257A (en) * | 2018-09-04 | 2019-01-08 | 广州源起健康科技有限公司 | A kind of time-resolved fluoroimmunoassay detection method based on magnetic particle |
DE102018123955B4 (en) | 2017-09-28 | 2024-08-01 | Shenzhen New Industries Biomedical Engineering Co., Ltd. | Measuring chamber, working method of the measuring chamber, chemiluminescence measuring method of the measuring chamber and chemiluminescence detector |
-
2017
- 2017-08-15 CN CN201721015724.9U patent/CN207036854U/en active Active
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102018123955B4 (en) | 2017-09-28 | 2024-08-01 | Shenzhen New Industries Biomedical Engineering Co., Ltd. | Measuring chamber, working method of the measuring chamber, chemiluminescence measuring method of the measuring chamber and chemiluminescence detector |
CN109164257A (en) * | 2018-09-04 | 2019-01-08 | 广州源起健康科技有限公司 | A kind of time-resolved fluoroimmunoassay detection method based on magnetic particle |
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