CN109142709A - A kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument - Google Patents

A kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument Download PDF

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Publication number
CN109142709A
CN109142709A CN201811016241.XA CN201811016241A CN109142709A CN 109142709 A CN109142709 A CN 109142709A CN 201811016241 A CN201811016241 A CN 201811016241A CN 109142709 A CN109142709 A CN 109142709A
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CN
China
Prior art keywords
liquid relief
withdraw
component
sliding panel
needle
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Granted
Application number
CN201811016241.XA
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Chinese (zh)
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CN109142709B (en
Inventor
李根平
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Guangzhou Origin Health Technology Co Ltd
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Guangzhou Origin Health Technology Co Ltd
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Priority to CN201811016241.XA priority Critical patent/CN109142709B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument, liquid relief moves back tube assembly and withdraw of the needle head selection component is installed in big sliding panel front middle and lower part;It punctures liquid relief stepper motor and is vertically mounted on the rack back side, the output shaft of puncture liquid relief stepper motor upward, and is connect via liquid relief synchronous belt component is punctured with the screw drive punctured in liquid relief screw drive component;It punctures the nut in liquid relief screw drive component and is mounted on big sliding back, puncture liquid relief stepper motor and drive screw rod rotation, the nut matched with screw rod drives big sliding panel to slide up and down, and related liquid relief moves back tube assembly and withdraw of the needle head selection component moves up and down;It moves back to intert in tube assembly due to the liquid relief on big sliding panel and is provided with withdraw of the needle head selection component, realizing can puncture but also liquid relief in same mechanism, it is not only simple in structure compact, low in cost, and being conducive to the simplification of checkout procedure, the medical institutions for being very suitable to China use, popularize.

Description

A kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument
Technical field
The present invention relates to industries institute's used times such as in-vitro diagnosis and biomedicine, animal epidemic, food safety and drug screening Between the puncture liquid relief of resolved fluorometric immunoassay instrument field more particularly to a kind of time-resolved fluorescence immunoassay instrument fill It sets.
Background technique
POCT real-time test (Point of Care Testing) is in-vitro diagnosis industry labelled immune skill in recent years The important development direction of art and fastest-rising branch.Technology involved in POCT is varied, in brief, Ke Yifen Simply to develop the color, enzyme label, immunoassay, optically and electrically biosensor, Electrochemical Detection, spectrophotometric and biochip Deng.
Immuno-labelling technique undergoes over one hundred year developing history, can be by immuno-labelling technique according to the difference of marker Detection method is divided into: 1, radiommunoassay, immunoradiometric assay (RIA, IRMA);2, fluoroimmunoassay (FIA);3, enzyme is exempted from Epidemic disease analyzes (EIA);4, golden labelling immunoassay;5, bioluminescence immunoassay (BIA);6, enzyme-fluoroimmunoassay (E- CIA);7, chemiluminescence immune assay (CLIA);8, time-resolved fluoroimmunoassay (TRFIA);9, electrochemical luminescence is immune It analyzes (ECLIA).
Time-resolved fluoroimmunoassay (TRFIA), using lanthanide chelate europium, terbium, samarium, dysprosium as marker, tool There are wider excitation spectrum, relatively narrow emission spectrum, advantageously reduce background, improves sensitivity;Ultraviolet excitation has higher amount Sub- yield, larger Stokes displacement, the spectrum for avoiding excitation spectrum and fluorescence emission spectrum and bio-matrix from emitting is overlapped, glimmering The advantages that light decay time is long, it is more wider than conventional fluorescent substance detection range, specific more preferable.
Time-resolved fluorescence immunoassay instrument is a kind of instrument that ultramicro-analysis is carried out using rare earth marker, basic Principle is that reagent is made in antibody rare earth element label, and under the irradiation of specific light source, reagent inspires fluorescence, by one section Background interference fluorescence is eliminated in the delay of time, and the as required fluorescence issued by marker carries out optics point to the fluorescence Analysis, can make diagnosis.
But part-time resolved immuno analyzer currently on the market, the puncture and liquid relief of reagent strip the step of in, It is essentially all to be implemented using more than two mechanisms, not only structure is complicated, higher cost, also causes checkout procedure complicated Change.
Summary of the invention
In order to solve the above technical problems, the present invention provides a kind of puncture liquid relief dress of time-resolved fluorescence immunoassay instrument It sets, it is simple and compact for structure, low in cost, and be conducive to the simplification of checkout procedure.
Technical scheme is as follows: a kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument, including wears Thorn liquid relief stepper motor, puncture liquid relief synchronous belt component, puncture liquid relief screw drive component, liquid relief move back tube assembly, the choosing of withdraw of the needle head It selects component, puncture liquid relief guide rail slide block component and big sliding panel;Wherein, the liquid relief moves back tube assembly and withdraw of the needle head selection component is equal It is mounted on the positive middle and lower part of big sliding panel;The back side of the big sliding panel is by screw and punctures in liquid relief guide rail slide block component Sliding block be connected, it is described puncture liquid relief guide rail slide block component in two guide rails rack is being fixed on just by screw interval vertical Face;The back side for puncturing liquid relief stepper motor and being vertically mounted on rack via corresponding fixing piece, and the puncture liquid relief stepping The output shaft of motor is arranged upward, and is connected via corresponding bearing with the synchronous pulley punctured in liquid relief synchronous belt component It connects;The screw rod punctured in liquid relief screw drive component is also vertically mounted on the back of rack via corresponding bearing and fixing piece Face, and the upper end of the screw rod is connected via corresponding bearing with another synchronous pulley punctured in liquid relief synchronous belt component; The nut punctured in liquid relief screw drive component is mounted on the back side of big sliding panel via corresponding fixing piece;The puncture Synchronous belt in liquid relief synchronous belt component is sleeved on the two synchronous pulleys, under the driving for puncturing liquid relief stepper motor Screw rod rotation is driven, and the nut by matching with the screw rod drives the sliding block at big sliding panel and its back side to glide along guide rail It is dynamic, it is thus related to be mounted on that the positive liquid relief of big sliding panel moves back tube assembly and withdraw of the needle head selection component integrally moves up and down.
The Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument, in which: the nut is located at the vertical of big sliding panel To on central axes.
The Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument, in which: it includes liquid relief that the liquid relief, which moves back tube assembly, Move back pipe motor fixing plate, liquid relief moves back pipe screw motor, liquid relief moves back pipe guide rail slide block component, small sliding panel, syringe push plate, liquid relief Move back pipe motor nut, multiple puncture needles, syringe fixed plate and Duo Zhi liquid relief syringe;It is horizontal that the liquid relief moves back pipe motor fixing plate To the front for being vertically fixed on big sliding panel, the liquid relief, which moves back pipe screw motor and is mounted on liquid relief, is moved back on pipe motor fixing plate, and The screw rod that the liquid relief moves back pipe screw motor moves back pipe motor fixing plate across liquid relief and is arranged vertically downward;It is sliding that the liquid relief moves back pipe guide rail Two guide rails in block assembly are fixed on liquid relief by screw perpendicular separation and move back big sliding panel front below pipe motor fixing plate, institute It states the back side of small sliding panel and liquid relief moves back the sliding block in pipe guide rail slide block component and is connected, the syringe push plate is fixed on small cunning The top of movable plate, the liquid relief are moved back pipe motor nut and are mounted in the syringe push plate, and the spiral shell of pipe screw motor is moved back with liquid relief Bar matches;Multiple puncture needle perpendicular separations are fixed on the bottom surface of small sliding panel;The syringe fixed plate is moved back positioned at liquid relief The lower section of pipe motor fixing plate, and move back pipe motor fixing plate with liquid relief via two root posts and be connected;More liquid relief syringes hang down Straight interval is mounted on the top surface of syringe fixed plate, and the front edge of the syringe push plate is provided with multiple adapters at more The card slot of liquid relief syringe tail portion.
The Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument, in which: moved back below pipe motor fixing plate in liquid relief Big sliding panel front, optocoupler sensor is connected with via corresponding fixing piece, for incuding locating for syringe push plate up and down Position.
The Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument, in which: the withdraw of the needle head assembly includes multiple moves back Syringe needle column, multiple withdraw of the needle plates, withdraw of the needle head stepper motor, withdraw of the needle head synchronous belt component and withdraw of the needle head guide rail slide block component;Wherein, often Two withdraw of the needle headpins are installed via corresponding linear bearing in the syringe fixed plate at a liquid relief syringe rear, are moved back each The upper half of syringe needle column is set with a spring, and the lower end of the two withdraw of the needle headpins is all connected with one block of withdraw of the needle plate, the withdraw of the needle plate Front end is provided with the notch that an adaptation returns liquid relief injector head syringe needle;The withdraw of the needle head stepper motor is via corresponding fixed Part lateral inward is connected to the side of small sliding panel, and the output shaft of the withdraw of the needle head stepper motor is via corresponding bearing and the withdraw of the needle Head synchronous belt component in a synchronous pulley be connected, another synchronous pulley in the withdraw of the needle head synchronous belt component via Corresponding bearing and connecting shaft are connected to the other side of small sliding panel;Guide rail in the withdraw of the needle head guide rail slide block component passes through spiral shell Nail is secured transverse to the positive lower end of small sliding panel, and the sliding block in the withdraw of the needle head guide rail slide block component is via corresponding connector Be connected with the synchronous belt in withdraw of the needle head synchronous belt component, and the synchronous belt be sleeved on two in withdraw of the needle head synchronous belt component it is same It walks on belt wheel.
The puncture liquid-transfering device of a kind of time-resolved fluorescence immunoassay instrument provided by the present invention, due in big sliding panel On liquid relief move back in tube assembly intert be provided with withdraw of the needle head select component, realizing can puncture but also move in same mechanism Liquid is not only simple in structure simplification compact, low in cost, and being also beneficial to checkout procedure, is particularly suitable for using instant Reagent can detect one or more parts sample simultaneously, and sample dosage is less, operation also it is easy quickly, you can get it within 30 minutes as a result, Patient's waiting time is greatly reduced, testing result is also more stable;The medical institutions for being very suitable to China use, promote With it is universal.
Detailed description of the invention
Fig. 1 is the perspective view that time-resolved fluorescence immunoassay instrument of the present invention punctures liquid-transfering device embodiment;
Fig. 2 is the amplification stereogram that liquid relief in Fig. 1 of the present invention moves back tube assembly;
Fig. 3 is the amplification stereogram of the withdraw of the needle head selection component in Fig. 1 of the present invention.
Specific embodiment
Below with reference to attached drawing, a specific embodiment of the invention and embodiment are described in detail, described tool Body embodiment only to explain the present invention, is not intended to limit a specific embodiment of the invention.
As shown in connection with fig. 1, Fig. 1 is that time-resolved fluorescence immunoassay instrument of the present invention punctures liquid-transfering device embodiment solid Figure, the puncture liquid-transfering device 4 include puncturing liquid relief stepper motor 41, puncture liquid relief synchronous belt component 42, puncture liquid relief screw rod to pass Dynamic component 43, liquid relief move back tube assembly 44, withdraw of the needle head selection component 45, puncture liquid relief guide rail slide block component (not shown go out) and slide greatly Movable plate 46;It is specific:
The liquid relief moves back tube assembly 44 and withdraw of the needle head selection component 45 is installed in the positive middle and lower part of big sliding panel 46;It is described big The back side of sliding panel 46 is connected by screw with the sliding block punctured in liquid relief guide rail slide block component, and the puncture liquid relief guide rail is sliding Two guide rails in block assembly are fixed on vertical plate (not shown go out, similarly hereinafter) front of instrument support by screw interval vertical;It is described The vertical plate back side that liquid relief stepper motor 41 is vertically mounted on instrument support via corresponding fixing piece is punctured, and the puncture liquid relief walks Output shaft into motor 41 is arranged upward, and via corresponding bearing and punctures a synchronous belt in liquid relief synchronous belt component 42 Wheel is connected;
The screw rod punctured in liquid relief screw drive component 43 is also vertically mounted on instrument via corresponding bearing and fixing piece The vertical plate back side of bracket, and the upper end of the screw rod via corresponding bearing and puncture in liquid relief synchronous belt component 42 another is same Step belt wheel is connected;The nut punctured in liquid relief screw drive component 43 is mounted on big sliding panel via corresponding fixing piece 46 back side, and the nut is located in the longitudinal central axis line of the big sliding panel 46;In the puncture liquid relief synchronous belt component 42 Synchronous belt be sleeved on the two synchronous pulleys, for puncture liquid relief stepper motor 41 driving under drive screw rod rotation, And the nut by matching with the screw rod drives the sliding block at big sliding panel 46 and its back side to slide up and down along guide rail, it is thus related It is mounted on that the positive liquid relief of big sliding panel 46 moves back tube assembly 44 and withdraw of the needle head selection component 45 is whole moves up and down, thus according to inspection It surveys needs and completes the movement punctured, liquid relief and/or the selective withdraw of the needle are first-class.
In conjunction with shown in Fig. 2 and Fig. 3, Fig. 2 is the amplification stereogram that liquid relief in Fig. 1 of the present invention moves back tube assembly, and Fig. 3 is this hair The amplification stereogram of withdraw of the needle head selection component in bright Fig. 1;Specifically, it includes that liquid relief moves back pipe motor that the liquid relief, which moves back tube assembly 44, Fixed plate 442, liquid relief move back pipe screw motor 441, liquid relief moves back pipe guide rail slide block component 444, small sliding panel 451, syringe push plate 452, liquid relief moves back pipe motor nut 458, multiple puncture needles 456, syringe fixed plate 443, more liquid relief syringes 445 and optocoupler Sensor 457;It is specific:
The liquid relief moves back the front that pipe motor fixing plate 442 is laterally vertically fixed on big sliding panel 46, and the liquid relief moves back pipe screw rod Motor 441 is mounted on liquid relief and moves back on pipe motor fixing plate 442, and the liquid relief move back pipe screw motor 44 screw rod pass through liquid relief move back pipe Motor fixing plate 442 is arranged vertically downward;The liquid relief move back two guide rails in pipe guide rail slide block component 444 by screw it is vertical between Every being fixed on, the big sliding panel 46 that liquid relief is moved back below pipe motor fixing plate 442 is positive, the back side of the small sliding panel 451 and liquid relief The sliding block moved back in pipe guide rail slide block component 444 is connected, and the syringe push plate 452 is fixed on the top of small sliding panel 451, institute It states liquid relief and moves back pipe motor nut 458 and be mounted in the syringe push plate 452, and move back the screw rod phase of pipe screw motor 441 with liquid relief Cooperation, for being driven by moving back pipe motor nut 458 with the liquid relief that screw rod cooperates under the driving that liquid relief moves back pipe screw motor 44 The sliding block of syringe push plate 452, small sliding panel 451 and its back side is slided up and down along guide rail;Multiple 456 perpendicular separations of puncture needle are solid It is scheduled on the bottom surface of small sliding panel 451, the movement for needing to complete to puncture according to detection;
The syringe fixed plate 443 is located at liquid relief and moves back the lower section of pipe motor fixing plate 442, and moves back via two root posts and liquid relief Pipe motor fixing plate 44 is connected;More 445 perpendicular separations of liquid relief syringe are mounted on the top surface of syringe fixed plate 443, The front of the syringe push plate 452 is used for root along multiple adapters are provided in the card slot of more 445 tail portions of liquid relief syringe Need to complete the movement of liquid relief according to detection;
The optocoupler sensor 457 is connected to the big sliding that liquid relief moves back 442 lower section of pipe motor fixing plate via corresponding fixing piece 46 front of plate is in upper or the next for incuding the location of syringe push plate 452.
Specifically, the withdraw of the needle head assembly 45 includes multiple withdraw of the needle headpins 446, multiple withdraw of the needle plates 447, withdraw of the needle head stepping electricity Machine 453, withdraw of the needle head synchronous belt component 454 and withdraw of the needle head guide rail slide block component 455;Wherein, each 445 rear of liquid relief syringe Two withdraw of the needle headpins 446 are installed via corresponding linear bearing in syringe fixed plate 443, in each withdraw of the needle headpin 446 The upper half is set with a spring, and the withdraw of the needle headpin 446 for keeping it internal restores in the absence of external forces to initial bit It sets, and the lower end of the two withdraw of the needle headpins 446 is all connected with one block of withdraw of the needle plate 447, the front end of the withdraw of the needle plate 447 is provided with an adaptation Return the notch of 445 head syringe needle of liquid relief syringe;
The withdraw of the needle head stepper motor 453 is connected to the side of small sliding panel 451 via corresponding fixing piece lateral inward, and should The output shaft of withdraw of the needle head stepper motor 453 is via a synchronous pulley in corresponding bearing and withdraw of the needle head synchronous belt component 454 It is connected, another synchronous pulley in the withdraw of the needle head synchronous belt component 454 is connected to via corresponding bearing and connecting shaft The other side of small sliding panel 451;Guide rail in the withdraw of the needle head guide rail slide block component 455 is secured transverse to small sliding by screw The positive lower end of plate 451, the sliding block in the withdraw of the needle head guide rail slide block component 455 are synchronous with withdraw of the needle head via corresponding connector It is connected with the synchronous belt in component 454, and the synchronous belt is sleeved on two synchronous pulleys in withdraw of the needle head synchronous belt component 454 On, for being moved to needs along guide rail by synchronous belt band movable slider and returning under the driving of the withdraw of the needle head stepper motor 453 Subsequent two withdraws of the needle headpin, 446 top of liquid relief syringe 445 of syringe needle, and the driving of pipe screw motor 441 is moved back in the liquid relief Under, drive small sliding panel 451 and sliding block to move down by nut, to press corresponding two withdraws of the needle headpin 446 and overcome two springs Elastic force, linkage two withdraw of the needle headpins, 446 lower end withdraw of the needle plate 447 move down, completion return the 445 head syringe needle of liquid relief syringe Movement, and when small sliding panel 451 and sliding block move up, using the elastic force for two springs being sleeved on two withdraws of the needle headpin 446, Make two withdraws of the needle headpin 446 and connect the withdraw of the needle plate 447 of its lower end to move up return.
It should be understood that the foregoing is merely illustrative of the preferred embodiments of the present invention, it is not sufficient to limit of the invention Technical solution within the spirit and principles in the present invention, can add according to the above description for those of ordinary skills With increase and decrease, replacement, transformation or improvement, and all these increases and decreases, replacement, transformation or improved technical solution, it all should belong to this The protection scope of invention appended claims.

Claims (5)

1. a kind of puncture liquid-transfering device of time-resolved fluorescence immunoassay instrument, which is characterized in that including puncturing liquid relief stepping electricity Machine, puncture liquid relief synchronous belt component, puncture liquid relief screw drive component, liquid relief move back tube assembly, withdraw of the needle head selection component, puncture and move Liquid guide rail slide block component and big sliding panel;Wherein, the liquid relief moves back tube assembly and withdraw of the needle head selection component is installed in big sliding The positive middle and lower part of plate;The back side of the big sliding panel is connected by screw with the sliding block punctured in liquid relief guide rail slide block component It connects, two guide rails punctured in liquid relief guide rail slide block component are fixed on the front of rack by screw interval vertical;It is described to wear Thorn liquid relief stepper motor is vertically mounted on the back side of rack, and the output of the puncture liquid relief stepper motor via corresponding fixing piece Axis is arranged upward, and is connected via corresponding bearing with the synchronous pulley punctured in liquid relief synchronous belt component;It is described to wear Screw rod in thorn liquid relief screw drive component is also vertically mounted on the back side of rack, and the spiral shell via corresponding bearing and fixing piece The upper end of bar is connected via corresponding bearing with another synchronous pulley punctured in liquid relief synchronous belt component;The puncture moves Nut in liquid screw drive component is mounted on the back side of big sliding panel via corresponding fixing piece;The puncture liquid relief synchronous belt Synchronous belt in component is sleeved on the two synchronous pulleys, for driving screw rod rotation under the driving for puncturing liquid relief stepper motor Turn, and the nut by matching with the screw rod drives the sliding block at big sliding panel and its back side to slide up and down along guide rail, thus connects Band be mounted on the positive liquid relief of big sliding panel move back tube assembly and the withdraw of the needle head selection component integrally move up and down.
2. Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument according to claim 1, it is characterised in that: the nut In the longitudinal central axis line of big sliding panel.
3. Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument according to claim 1, it is characterised in that: the liquid relief Moving back tube assembly includes that liquid relief moves back pipe motor fixing plate, liquid relief moves back pipe screw motor, liquid relief moves back pipe guide rail slide block component, small sliding Plate, syringe push plate, liquid relief move back pipe motor nut, multiple puncture needles, syringe fixed plate and Duo Zhi liquid relief syringe;The shifting Liquid moves back the front that pipe motor fixing plate is laterally vertically fixed on big sliding panel, and the liquid relief, which moves back pipe screw motor and is mounted on liquid relief, moves back On pipe motor fixing plate, and the liquid relief moves back the screw rod of pipe screw motor and passes through liquid relief and move back pipe motor fixing plate and be arranged vertically downward; The liquid relief, which moves back two guide rails in pipe guide rail slide block component and is fixed on liquid relief by screw perpendicular separation, moves back under pipe motor fixing plate The big sliding panel front of side, the back side of the small sliding panel moves back the sliding block in pipe guide rail slide block component with liquid relief and is connected, described Syringe push plate is fixed on the top of small sliding panel, and the liquid relief is moved back pipe motor nut and is mounted in the syringe push plate, and with The screw rod that liquid relief moves back pipe screw motor matches;Multiple puncture needle perpendicular separations are fixed on the bottom surface of small sliding panel;The note Emitter fixed plate is located at the lower section that liquid relief moves back pipe motor fixing plate, and moves back pipe motor fixing plate with liquid relief via two root posts and be connected It connects;More liquid relief syringe perpendicular separations are mounted on the top surface of syringe fixed plate, and the front edge of the syringe push plate is set Multiple adapters are equipped in the card slot of more liquid relief syringe tail portions.
4. Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument according to claim 3, it is characterised in that: moved back in liquid relief Big sliding panel front below pipe motor fixing plate, is connected with optocoupler sensor via corresponding fixing piece, for incuding injection Upper and lower position locating for device push plate.
5. Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument according to claim 1, it is characterised in that: the withdraw of the needle Head assembly includes multiple withdraw of the needle headpins, multiple withdraw of the needle plates, withdraw of the needle head stepper motor, withdraw of the needle head synchronous belt component and withdraw of the needle head guide rail Slide block assembly;Wherein, two are installed via corresponding linear bearing in the syringe fixed plate at each liquid relief syringe rear Withdraw of the needle headpin is set with a spring in the upper half of each withdraw of the needle headpin, and the lower end of the two withdraw of the needle headpins is all connected with one piece Withdraw of the needle plate, the front end of the withdraw of the needle plate are provided with the notch that an adaptation returns liquid relief injector head syringe needle;The withdraw of the needle head stepping Motor is connected to the side of small sliding panel, and the output shaft warp of the withdraw of the needle head stepper motor via corresponding fixing piece lateral inward It is connected by corresponding bearing with a synchronous pulley in withdraw of the needle head synchronous belt component, in the withdraw of the needle head synchronous belt component Another synchronous pulley is connected to the other side of small sliding panel via corresponding bearing and connecting shaft;The withdraw of the needle head guide rail slide block Guide rail in component is secured transverse to the positive lower end of small sliding panel by screw, the cunning in the withdraw of the needle head guide rail slide block component Block is connected via corresponding connector with the synchronous belt in withdraw of the needle head synchronous belt component, and to be sleeved on withdraw of the needle head same for the synchronous belt Step is on two synchronous pulleys in component.
CN201811016241.XA 2018-09-02 2018-09-02 Puncture pipetting device of time-resolved fluoroimmunoassay analyzer Active CN109142709B (en)

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CN110631878B (en) * 2019-10-28 2022-06-17 宁波美生医疗器材有限公司 Sample transfer mechanism of liquid-based cell automatic sheet-making medical equipment
CN113736627A (en) * 2021-09-30 2021-12-03 北京卓诚惠生生物科技股份有限公司 PCR system liquid injection device capable of automatically replacing syringe needle
CN113736627B (en) * 2021-09-30 2022-04-08 北京卓诚惠生生物科技股份有限公司 PCR system liquid injection device capable of automatically replacing syringe needle

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