CN213580985U - Universal immunoassay analyzer for various reagent cards - Google Patents

Universal immunoassay analyzer for various reagent cards Download PDF

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Publication number
CN213580985U
CN213580985U CN202022325867.8U CN202022325867U CN213580985U CN 213580985 U CN213580985 U CN 213580985U CN 202022325867 U CN202022325867 U CN 202022325867U CN 213580985 U CN213580985 U CN 213580985U
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module
card
reagent
reagent card
axis
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游延伟
余占江
陈永强
程小雷
郭永峰
王陈
张少康
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Pro Med Beijing Technology Co ltd
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Pro Med Beijing Technology Co ltd
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Abstract

The utility model provides a general immunoassay appearance of multiple reagent card, including outside visual part and inner structure, outside visual part includes equipment shell, print module, display module and reagent card box, and print module and display module are installed respectively in the lateral part of equipment shell and the place ahead, and the reagent card box is used for placing the reagent card to be detected; the internal structure of the immunoassay analyzer comprises a CPU main control module, a Y-axis motion module, an X-axis motion module, a photoelectric data acquisition module and a card inlet detection and identification module, wherein the card inlet detection and identification module comprises a card inlet detection sensor and a one-dimensional wharf, the immunoassay analyzer drives the photoelectric data acquisition module to reciprocate along the X-axis direction by the X-axis motion module in the detection process, and a reagent card box on the Y-axis motion module drives the reagent card to reciprocate along the Y-axis direction. The immunoassay analyzer is simple to operate, high in detection efficiency, accurate and reliable in detection result, and suitable for single cards and multi-card.

Description

Universal immunoassay analyzer for various reagent cards
Technical Field
The utility model belongs to the check out test set field, in particular to general immunoassay appearance of multiple reagent card.
Background
The immunoassay is an analysis technique based on characteristic reactions of antigens and antibodies, and is mainly classified into radioimmunoassay, enzyme immunoassay, fluorescence immunoassay, chemiluminescence assay, fluorescein immunoassay, and the like according to different labeling techniques. The analyzer of this type generally detects the sample by adopting an up-down structure, that is, the photoelectric data acquisition module is arranged above and below the sample to be detected, and the photoelectric data acquisition module and the sample to be detected move relatively to each other to acquire data. The structure of the photoelectric data acquisition module is determined by the type of immunoassay.
At present, domestic similar immunity analyzers are mainly used for detecting reagent cards in hospital clinical laboratory. The structure of the device is basically composed of an output and input module, a motion module, a photoelectric data acquisition module, a CPU main control module, a printing module and the like. And is also generally equipped with a standard music collection module (IC card/ID card/code scanning gun), a power supply module, and the like. The immunoassay analyzer can only detect a single reagent card, and because the information carried by the single reagent card is limited, when a single sample needs to detect a plurality of items, the analyzer needs to repeat detection for many times, so that the operation is complex, the detection efficiency is low, the detection time interval is long, and the accuracy of the detection result is influenced. Although many detection items are borne by the multi-link cards in the market, the multi-link cards lack related detection equipment, so that the multi-link cards can only perform qualitative analysis on multiple samples and cannot perform quantitative analysis on samples to be detected.
Therefore, how to obtain an immunoassay analyzer suitable for the analysis and detection of the amount of various types of reagent cards is a problem to be solved.
Disclosure of Invention
Problem to prior art existence, the utility model aims to provide an immunoassay appearance that multiple reagent card is general, not only easy operation, detection efficiency are high, the testing result is accurate reliable, single card moreover, ally oneself with the card all be suitable for more.
The utility model aims at realizing through the following technical scheme:
the immunoassay analyzer comprises an external visible part and an internal structure, wherein the external visible part comprises an equipment shell, a printing module, a display module and a reagent card box, the printing module and the display module are respectively arranged on the side part and the front part of the equipment shell, and the reagent card box is used for placing a reagent card to be detected; the internal structure of the immunity analyzer comprises a CPU main control module, a Y-axis motion module, an X-axis motion module, a photoelectric data acquisition module and a card-entering detection and identification module, the CPU main control module is arranged on a bottom plate of the equipment shell, the Y-axis motion module is positioned above the CPU main control module, and is connected and fixed with the bottom plate through a supporting column, an X-axis motion module is arranged above a Y-axis motion module, a photoelectric data acquisition module is arranged on the X-axis motion module, the card-entering detection and identification module comprises a card-entering detection sensor and a one-dimensional wharf, the card-entering detection sensor is arranged on the equipment shell, the one-dimensional wharf is arranged on the X-axis movement module, in the detection process of the immunoassay analyzer, the X-axis motion module drives the photoelectric data acquisition module to reciprocate along the X-axis direction, and the reagent card box on the Y-axis motion module drives the reagent card to reciprocate along the Y-axis direction.
Furthermore, a light shield is further arranged on a bottom plate of the equipment shell, and the card feeding detection sensor is installed on the light shield; the one-dimensional wharf is arranged on a transverse support plate of the X-axis movement module through a one-dimensional code support.
Furthermore, the CPU main control module is integrated with a WiFi module and a Bluetooth module and comprises a plurality of interfaces for an external modular printer, a two-dimensional code scanner, a keyboard and a mouse.
Further, Y axle motion module includes main extension board, the connecting plate, the reagent card box, Y axle motor, the hold-in range hypoplastron, the hold-in range clamp plate, the reagent card apron, left socle and right branch frame, wherein, the connecting plate passes through guide rail slider and connects on main extension board, hold-in range hypoplastron fixed mounting is on the connecting plate, the hold-in range hypoplastron presss from both sides tight hold-in range with the hold-in range clamp plate, it is linear motion along the Y axle under Y axle motor drives, the reagent card box is fixed on the connecting plate, reagent card apron is installed to reagent card box's reagent draw-in groove top.
Furthermore, the X-axis motion module comprises a transverse support plate, a connecting piece, an X-axis motor and a pushing and clamping rod, the transverse support plate is connected with the main support plate of the Y-axis motion module through a left support and a right support, and the X-axis motor is installed on the transverse support plate and drives the pushing and clamping rod to reciprocate along the X-axis direction.
Furthermore, the photoelectric data acquisition module comprises a light-emitting box and a light-emitting box bracket, and the light-emitting box is arranged on the connecting piece of the X-axis movement module through the light-emitting box bracket.
Furthermore, a partial cut is designed at the left upper part of the clamping groove of the reagent card box, so that the reagent card box can be respectively suitable for single cards and multi-card; the bottom design of draw-in groove has rib and elastic bulge, the rib suits with the different specification reagent card bottom grooves that cooperate and use.
Furthermore, the surface of the cover plate of the reagent card is provided with a first hollow structure and a second hollow structure corresponding to the position of each reagent card channel, the first hollow structure corresponds to the detection window of each channel of the reagent card, and the second hollow structure corresponds to the sampling hole of each channel of the reagent card.
Furthermore, an upward bending structure is designed at the tail end of the reagent card cover plate; the lower part of the reagent card cover plate is designed with a lower sliding surface with a certain inclination angle.
Further push away the kelly at horizontal extension board bottom of X axle motion module is installed, the front end of reagent card box is designed with the recess, pushes away kelly and mutually supports and both have certain clearance with this recess.
The utility model discloses compare prior art's beneficial effect does:
immunoassay appearance, wherein reagent card box installs on the Y axle motion module of equipment and can follow Y axle reciprocating motion, after operating personnel inserted the reagent card of joining the sample, the reagent card enters the inside detection of equipment, can abandon the card automatically after the detection is accomplished, avoids operating personnel to get the card once more, not only easy operation, detection efficiency height, testing result are accurate reliable, single card moreover, the card that ally oneself more all is suitable for.
Drawings
The invention is further illustrated by the following figures and examples.
FIG. 1 is a schematic view of a visible portion of an immunoassay analyzer for multiple reagent cards according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of the internal structure of an immunoassay analyzer for multiple reagent cards according to an embodiment of the present invention;
FIG. 3 is a schematic structural diagram of the Y-axis motion module;
FIG. 4 is a schematic structural diagram of the X-axis motion module, the photoelectric data acquisition module and the card-entry detection and identification module;
FIG. 5 and FIG. 6 are schematic views of a-type and b-type light-emitting box brackets, respectively;
FIG. 7 is a schematic view of the structure of the reagent cartridge;
FIG. 8 is a schematic view of the structure of the reagent card cover plate;
FIG. 9 is a schematic structural view of the pushing rod and the groove of the reagent cartridge;
fig. 10 is a cross-sectional view of fig. 9.
Detailed Description
Example 1
The embodiment provides an immunoassay analyzer universal for multiple reagent cards, which comprises an external visible part and an internal structure, wherein as shown in fig. 1, the external visible part comprises an equipment shell 1, a printing module 2, a display module 3 and a reagent card box 503, and the printing module is a built-in thermal printer and can print detection results at any time; the display module is a touch display screen, the current running state and the detection result of the equipment can be visually displayed, an operator can input corresponding information from the display module, the printing module and the display module are respectively arranged on the side part and the front part of the equipment shell, and the touch display screen has a certain inclination angle, so that the operation of the operator is facilitated; the reagent card box is used for placing a reagent card to be detected; as shown in fig. 2, the internal structure of the immunoassay analyzer comprises a CPU main control module 4, a Y-axis motion module 5, an X-axis motion module 6, a photoelectric data acquisition module 7 and a card-entering detection and identification module 8, wherein the CPU main control module is installed on a bottom plate 101 of an equipment housing and is a control core of the whole equipment, the Y-axis motion module is located above the CPU main control module and is connected and fixed with the bottom plate through a support pillar 102, the X-axis motion module is installed above the Y-axis motion module, the photoelectric data acquisition module is installed on the X-axis motion module, as shown in fig. 4, the card-entering detection and identification module comprises a card-entering detection sensor 801 and a one-dimensional wharf 802, the card-entering detection sensor is installed on the equipment housing, the one-dimensional wharf is installed on the X-axis motion module, and during the detection process of the immunoassay analyzer, the X-axis motion module drives the photoelectric data acquisition, the reagent card box on the Y-axis motion module drives the reagent card to reciprocate along the Y-axis direction.
After an operator inserts a reagent card added with a sample, when a sensor 801 senses that the reagent card is inserted into the reagent card box 503, a Y-axis motor 506 of a Y-axis motion module 5 drives the reagent card box 503 to enter the equipment, a one-dimensional wharf 802 scans one-dimensional code information at the front end of an upper shell of the reagent card, the type of the reagent card is identified, and then whether the reagent card meets the detection requirement of the equipment or not is judged: if the signal is not matched, the signal is displayed on the touch display screen, and meanwhile, the buzzer gives an alarm. In the detection process, the X-axis motion module 6 drives the photoelectric data acquisition module 8 to move along the X-axis direction to reach the initial scanning position of the reagent card, and the reagent card box 503 of the Y-axis motion module 5 drives the reagent card to move along the Y-axis direction to start detecting the reagent card. When a single card is detected, the detection is finished after one-time scanning, the photoelectric data acquisition module is reset, and the card abandoning is started. When the multi-link card is detected, the first channel of the multi-link card is detected, the X-axis motion module 5 drives the photoelectric data acquisition module 8 to move to the next channel along the X-axis direction, the reagent card box 503 of the Y-axis motion module repeats the previous scanning action, the X-axis motion module and the Y-axis motion module move in coordination with each other until the multi-link card is detected, and the photoelectric data acquisition module 7 resets. After the scanning is completed, the photoelectric reagent card box 503 is driven by the Y-axis motor to continue moving along the Y-axis in the opposite direction, and the card is discarded. And after the card abandoning is finished, the reagent card box resets, the detection process is finished, and the next reagent card can be inserted for detection.
Furthermore, a WiFi module and a Bluetooth module are integrated on the CPU main control module 4, and various data transmission ways are provided. The external modular printer and the two-dimensional code scanner interface are provided, and the external printer and the code scanning gun can be connected. In addition, the device is also provided with external interfaces such as a keyboard, a mouse and the like, and is suitable for different operation habits of different operators.
As shown in fig. 3, the Y-axis motion module 5 mainly comprises a main support plate 501, a connection plate 502, a reagent cartridge 503, a Y-axis motor 504, a timing belt lower plate 505, a timing belt pressing plate 506, a reagent cartridge cover plate 507, a left support 508, a right support 509, and the like, as shown in fig. 3. The connecting plate 502 is connected to the main support plate 501 through a guide rail slider, the synchronous belt lower plate 505 is fixedly mounted on the connecting plate 502, the synchronous belt lower plate 505 and the synchronous belt pressing plate 506 clamp the synchronous belt, and the synchronous belt moves linearly along the Y axis under the drive of the Y-axis motor 504. The reagent card box 503 is fixed on the connection board 502, a reagent card cover plate 507 is arranged above the reagent card slot of the reagent card box 503, and the reagent card slot is arranged to be inserted with the reagent card 9.
As shown in fig. 4, the X-axis motion module 6 includes a transverse support plate 601, a connecting member 602, an X-axis motor 603, and a pushing rod 604, wherein the transverse support plate 601 is connected to the main support plate 501 of the Y-axis motion module 5 through a left bracket 508 and a right bracket 509; the light-emitting box 701 of the optoelectronic data acquisition module 7 is mounted on the connecting piece 602 of the X-axis movement module 6 through a light-emitting box bracket 702. The mounting hole of the transverse support plate 601 is a long round hole, so that the module can have a certain displacement in the X-axis direction, the transverse support plate is transversely moved in the assembling process, and the accuracy of the photoelectric data acquisition module in the initial position in the X direction is ensured. An X-axis motor 603 is mounted on the transverse support plate 601, and drives the card pushing rod 604 to reciprocate along the X-axis direction. The mounting hole of the light-emitting box support 702 is a long round hole, so that the photoelectric data acquisition module 7 has a certain displacement in the Y-axis direction, and the accuracy of the photoelectric data acquisition module 7 in the initial position in the Y-axis direction is ensured by adjusting the position of the mounting hole of the module. In addition, the module is designed with a type a, a type b and other light-emitting box brackets, as shown in fig. 5 and 6, and is used for adapting light-emitting boxes of different immunoassay technologies.
The card-entering detection and identification module 8 includes two parts, namely a card-entering detection sensor 801 and a one-dimensional wharf 802, as shown in fig. 4. The card-entering detection sensor 801 is installed on the light shield 103, and the one-dimensional wharf 802 is installed on the transverse support plate 601 of the X-axis motion module 6 through the one-dimensional code support 803. When the sensor 801 detects that a reagent card is inserted into the reagent card box 503, the CPU main control module 4 controls the Y-axis motor 504 to drive the reagent card box 503 to enter the warehouse to the one-dimensional code detection position, the one-dimensional wharf 802 scans the one-dimensional code information on the reagent card, the information matching is performed automatically for preparation detection, otherwise, the display screen displays that the information is not in accordance, and the operator performs the next operation.
Example 2
This embodiment is an improvement of the above embodiment 1, and is a refinement of the above embodiment regarding the reagent card box 503, as shown in fig. 7, a partial notch 5031 is designed at the left upper part of the card slot of the reagent card box 503, so that the reagent card box 503 can be respectively applied to special reagent cards of various specifications such as single card, triple card, quintuplet card, and the like. The bottom of the card slot is designed with ribs 5032 with different intervals, and the bottom of the multi-connection card matched with the device is designed with corresponding grooves. When the multi-gang card is inserted into the reagent card box, the ribs 5032 limit the multi-gang card, so that an operator is prevented from inserting different reagent cards into wrong positions during operation, and the operation efficiency is improved.
The bottom of the card slot of the reagent card box 503 is provided with an elastic protrusion 5033, when a reagent card is inserted into the reagent card box 503, the salient point of the elastic protrusion 5033 acts on the bottom of the reagent card, and the upper surface of the reagent card is tightly attached to the reagent card cover plate 507 under the action of elasticity, so that the position of the reagent card is unchanged in the testing process, and the accuracy of the testing result is ensured.
Example 3
This embodiment is a modification of embodiments 1 and 2, and is a refinement of the above embodiment regarding the reagent card cover 507, as shown in fig. 8, the surface of the reagent card cover 507 is designed to be hollow structures 5071, 5072. Hollow 5071 corresponds to the detection window of each channel of the reagent card, so that the photoelectric data acquisition module 7 can scan the reagent strip of one channel at a time in the detection process, the interference of reagent strips of other channels is avoided, the interference of reagent strips of other channels to be detected is also avoided, the accuracy of the detection result is ensured, and the operator can conveniently observe the chromatography effect of the reagent card. Hollow 5072 corresponds to the sampling hole of each channel of the reagent card, and is convenient for operators to observe the reagent card.
Upward bending structures 5073 are designed at the tail end of the reagent card cover plate 507, and when a reagent card is completely inserted into the reagent card box 503, the position of a sample adding hole of the reagent card is opposite to the bending structures 5073 of the reagent card cover plate 507, a gap is reserved between the sample adding hole and the bending structures, so that residual samples possibly existing at the sample adding hole are prevented from contacting the reagent card cover plate 507, cross infection among different reagent cards is avoided, and the accuracy of detection results is improved.
Example 4
This embodiment is an improvement of the above embodiments 1 to 3, and is a refinement of the above embodiments with respect to the X-axis moving module 6, as shown in fig. 9, a card pushing rod 604 is installed at the bottom of a transverse support plate 601 of the X-axis moving module 6; the front end of the reagent cartridge 503 is designed with a recess 5034, as shown in FIG. 7. After the whole device is assembled, the pushing rod is matched with the groove 5034 of the reagent card box 503 with a certain gap. After the photoelectric data acquisition module 7 detects the reagent card 9, the Y-axis motor 504 drives the reagent card box 503 to move forward, and after the reagent card 9 contacts the card pushing rod 604, the reagent card box 503 still moves forward under the resistance of the card pushing rod 604, as shown in fig. 10, so that the reagent card 9 finally separates from the reagent card box 503. The lower part of the card abandoning position is provided with a lower sliding surface 510 with an inclination angle of 30 degrees, and after the reagent card falls on the lower sliding surface 510, the reagent card slides out of the analyzer along the lower sliding surface 510 under the action of gravity and enters a special medical waste dustbin, so that the automatic card abandoning is completed. The whole card abandoning process is automatically completed by equipment without operation of an operator, so that the chance of the operator contacting a sample is reduced, and the personal safety of the operator is ensured.

Claims (10)

1. The immunoassay analyzer universal for multiple reagent cards comprises an external visible part and an internal structure, and is characterized in that the external visible part of the immunoassay analyzer comprises an equipment shell (1), a printing module (2), a display module (3) and a reagent card box (503), wherein the printing module and the display module are respectively arranged on the side part and the front part of the equipment shell, and the reagent card box is used for placing a reagent card (9) to be detected; the internal structure of the immunoassay analyzer comprises a CPU main control module (4), a Y-axis motion module (5), an X-axis motion module (6), a photoelectric data acquisition module (7) and a card-entering detection and identification module (8), wherein the CPU main control module is arranged on a bottom plate (101) of an equipment shell, the Y-axis motion module is positioned above the CPU main control module and is connected and fixed with the bottom plate through a support column (102), the X-axis motion module is arranged above the Y-axis motion module, the photoelectric data acquisition module is arranged on the X-axis motion module, the card-entering detection and identification module comprises a card-entering detection sensor (801) and a one-dimensional wharf (802), the card-entering detection sensor is arranged on the equipment shell, the one-dimensional wharf is arranged on the X-axis motion module, and the X-axis motion module drives the photoelectric data acquisition module to reciprocate along the X-axis direction in the detection process of the immunoassay, the reagent card box on the Y-axis motion module drives the reagent card to reciprocate along the Y-axis direction.
2. The immunoassay analyzer for multiple reagent cards of claim 1, wherein a light shield (103) is further disposed on the bottom plate (101) of the device housing (1), and the card-entering detection sensor (801) is mounted on the light shield; the one-dimensional wharf (802) is arranged on a transverse support plate (601) of the X-axis movement module (6) through a one-dimensional code support (803).
3. The immunoassay analyzer for multiple reagent cards of claim 1, wherein the CPU main control module (4) integrates a WiFi module and a bluetooth module, and comprises a plurality of interfaces for an external modular printer, a two-dimensional code scanner, a keyboard and a mouse.
4. The immunoassay analyzer general for multiple reagent cards according to claim 1, wherein the Y-axis movement module (5) comprises a main support plate (501), a connecting plate (502), a reagent card box (503), a Y-axis motor (504), a synchronous belt lower plate (505), a synchronous belt pressing plate (506), a reagent card cover plate (507), a left support (508) and a right support (509), wherein the connecting plate (502) is connected to the main support plate (501) through a guide rail slider, the synchronous belt lower plate (505) is fixedly installed on the connecting plate (502), the synchronous belt lower plate and the synchronous belt pressing plate (506) clamp the synchronous belt, the Y-axis motor (504) drives the synchronous belt to move linearly along the Y-axis, the reagent card box (503) is fixed on the connecting plate, the reagent card cover plate (507) is installed above the reagent card slot of the reagent card box, and the reagent card slot can be inserted.
5. The immunoassay analyzer for multiple reagent cards of claim 1, wherein the X-axis movement module (6) comprises a transverse support plate (601), a connecting member (602), an X-axis motor (603) and a card pushing rod (604), the transverse support plate is connected with the main support plate (501) of the Y-axis movement module (5) through a left support (508) and a right support (509), and the X-axis motor is mounted on the transverse support plate and drives the card pushing rod to reciprocate along the X-axis direction.
6. The immunoassay analyzer as claimed in claim 5, wherein the optoelectronic data collecting module (7) comprises a light emitting cassette (701) and a light emitting cassette holder (702), and the light emitting cassette is mounted on the connecting member (602) of the X-axis moving module (6) through the light emitting cassette holder.
7. The immunoassay analyzer for multiple reagent card applications of claim 4, wherein the reagent cartridge (503) has a notch (5031) at the upper left of the card slot to allow the reagent cartridge to be adapted for single card and multiple card; the bottom of the clamping groove is provided with a rib (5032) and an elastic bulge (5033), and the rib is adapted to the bottom grooves of the reagent cards of different specifications.
8. The immunoassay analyzer for multiple reagent cards of claim 4, wherein the surface of the cover plate (507) of the reagent card is provided with a first hollow structure (5071) and a second hollow structure (5072) corresponding to the channel position of each reagent card, the first hollow structure corresponds to the detection window of each channel of the reagent card, and the second hollow structure corresponds to the sampling hole of each channel of the reagent card.
9. The immunoassay analyzer for multiple reagent card use according to any one of claims 4, 7 or 8, wherein the reagent card cover plate (507) is provided with an upward bent structure (5073) at its distal end; the lower part of the reagent card cover plate is designed with a lower sliding surface (510) with a certain inclination angle.
10. The immunoassay analyzer for multiple reagent card applications of claim 1 or 5, wherein the bottom of the lateral support plate (601) of the X-axis motion module (6) is installed with a card pushing rod (604), the front end of the reagent card box (503) is designed with a groove (5034), and the card pushing rod and the groove are mutually matched and have a certain gap.
CN202022325867.8U 2020-10-19 2020-10-19 Universal immunoassay analyzer for various reagent cards Active CN213580985U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114047168A (en) * 2021-11-16 2022-02-15 江苏硕世生物科技股份有限公司 Optical-based reagent card identification and detection system and method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114047168A (en) * 2021-11-16 2022-02-15 江苏硕世生物科技股份有限公司 Optical-based reagent card identification and detection system and method

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