CN107490703A - A kind of multichannel Immunofluorescence test device - Google Patents
A kind of multichannel Immunofluorescence test device Download PDFInfo
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- CN107490703A CN107490703A CN201710650606.3A CN201710650606A CN107490703A CN 107490703 A CN107490703 A CN 107490703A CN 201710650606 A CN201710650606 A CN 201710650606A CN 107490703 A CN107490703 A CN 107490703A
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- China
- Prior art keywords
- sample introduction
- unit
- line slideway
- sliding block
- stirring hand
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00376—Conductive heating, e.g. heated plates
Abstract
The invention discloses a kind of multichannel Immunofluorescence test device, sample injection unit (1), bar code scanner (2), sample introduction stirring hand unit (3), incubation unit (4), censorship stirring hand unit (5), detection unit (6) present invention including installing on the table integrate multiple functions, multisample can be realized while incubated, pattern detection one by one, checkability is greatly improved, the standardization, automation and precision of multichannel immunofluorescence instrument is further improved.
Description
Technical field
The present invention relates to a kind of multichannel Immunofluorescence test device, belong to technical field of fluorescence detection.
Background technology
Immunofluorescence technique (Immunofluorescence assay, IFA) be by antibody antigen reaction specificity and
The technology that sensitiveness and the accuracy of micro- tracer be combined with each other, using fluorchrome as label, with known antibody
Or antigen is combined, but the immunological characteristic of its antibody or antigen is not influenceed, then by fluorescein-labeled antibody or anti-
Original work are standard reagent, for detecting and differentiating unknown antigen or antibody.Therefore fluorescence immunity analyzer is to utilize fluorescence
The detection means that the high susceptibility of technology is combined with the high degree of specificity of immunological technique.
Specificity fluorescent can directly use fluorescence microscope, can also be received with optical-electrical converter and be converted into electric signal
Further handle afterwards.Due to immunofluorescence assay can it is accurate, sensitive, quickly locate and detect some micro or ultramicron
Material, immunofluorescence technique have obtained at many aspects such as immunology, microbiology, pathology, oncology and clinical examination
Extensive use.
Immunofluorescence test can be carried out by pure manual operation or immunofluorescence analysis device at this stage, the former detects effect
Rate is low and precision is not high, and the latter generally only has a station, and automaticity is not high, and the efficiency detected during work is low, if
Standby use cost is higher.
Chinese patent CN 201520645476.0 discloses a kind of immunofluorescence analysis instrument, including analyzer housing, described
The side of analyzer housing is provided with test card sample introduction opening, is provided with the test card sample introduction opening and places position with some test cards
Magazine-type test card sample introduction box, the magazine-type test card sample introduction box is provided with bullet adjacent to one end of the test card sample introduction opening
Spring formula pushes away spline structure, the one end of the magazine-type test card sample introduction box away from the test card sample introduction opening and a belt drive
Structure connects, and the belt gear is provided with some test positions along its transmission direction, and is set above some test positions
There is a lead screw transmission mechanism, drive connection has test module in the lead screw transmission mechanism.The utility model can the progress of batch sample introduction
Batch testing, substantially increase its testing efficiency.
Chinese patent CN201320523643.5 discloses a kind of full-range C-reactive protein Immunofluorescence test point
Analysis apparatus, including analyzer and reagent strip, the analyzer include dripping system, the detection system being from left to right arranged on fuselage
System, coded system, light source, coded scanning device, motor and circuit control system, the dripping system, detecting system, coding system
System, light source and coded scanning device electrically connect with circuit control system respectively, and the dripping system, detecting system, coded system,
Light source and coded scanning device respectively with motor connection, the reagent strip be arranged in fuselage and positioned at dripping system, detecting system,
Coded system, light source, the lower section of coded scanning device.The utility model is by detection reagent bar and the supporting one of immunofluorescence analysis instrument
Change, high sensitivity, improve linear value, avoid non-specific responding to greatest extent, result accuracy is improved a lot, it is as a result more accurate
It is really reliable, and its detectable scope reaches 0-320mg/L, detection range is wider
Chinese patent CN 201220239595.2 discloses a kind of fluorescence immunity analyzer, including bottom plate, is installed on bottom plate
There are master control system and transmission system, transmission system includes chute and neck, and the upper end of chute is provided with light path detection
System, alignment system is installed on chute, master control system is connected with transmission system, light path detection and alignment system.
The run duration of the neck in transmission system is controlled by master control system, then when neck is run to the end of chute, card
Groove is fixed on the end of chute, and personnel easy to operation place detection card, and after detection card is fixed, neck transports card is detected
Behind the position specified, detection work is carried out, so, the placement accuracy of detection card is improved, improves detection efficiency.The utility model
Corresponding test card can be coordinated, determinand content in sample is detected, available for a variety of item detections, suitable for medical field
In clinical detection and family's prevention from suffering from the diseases self-test.
Chinese patent CN 201420652637.4 discloses a kind of fluorescence immunity analyzer, including the inspection of sample presentation unit, optics
Survey module, bar code scanning module, transmission module, control panel, display device, power switch, printer, radio frequency card reader, base
Plate and shell, power switch are installed on substrate and protrude from shell, and power switch is electrically connected with control panel, and control panel is installed on
It is on substrate and electric with optical detecting module, bar code scanning module, transmission module, display device, printer and radio frequency card reader
Connection；Transmission module is arranged on substrate, and sample presentation unit, optical detecting module and bar code scanning module are installed on transmission module.
The utility model fluorescence immunity analyzer, sample to be tested can be made within a very short time by optical detecting module, bar code scan mould
Block is identified, detected respectively, has saved detection time.Radio frequency card reader can identify the authority of user, display device and beat
Print machine convenient use person is seen detection information and can be fixed information with paper carrier.
The apparatus structure setting of above-mentioned patent notes is relatively simple, it is necessary to which manual steps are more, and instrument precision is not
It is enough, reliability, stability and the poor sensitivity of testing result, testing result can be had a certain impact.Other sense channel compared with
It is few, influence detection speed.
The content of the invention
Goal of the invention：The present invention provides a kind of multichannel Immunofluorescence test device, artificial in the prior art for solving
It is complex for operation step, batch detection, the reliability of batch sample testing result, stability can not be carried out and sensitivity is poor asks
Topic.It can make the reagent card article of instrument lay convenient, accurate positioning, and testing result is accurately quick., can when being detected
Sample characteristics of for example is not damaged while to ensure fast sample, facilitates multigroup sample quick replacement and is detected one by one, added
The accuracy of detection is ensure that while detection speed.
Technical scheme：To achieve the above object, the technical solution adopted by the present invention is：
A kind of multichannel Immunofluorescence test device, including installation sample injection unit on the table, bar code scanner,
Sample introduction stirring hand unit, unit, censorship stirring hand unit, detection unit are incubated, wherein：
The sample injection unit is used to insert reagent card article, and the insertion situation of detection reagent card article, while will detect
Insertion situation is sent to bar code scanner.
The bar code scanner is used for the signal according to photoelectric sensor transmission on the reagent card article in sample introduction tank
Bar code is read out, and then sends instructions to automatic sampling gun, and automatic sampling gun sets sample-adding amount automatically, into reagent card article
Sample is added, adds after sample automatic sampling gun to sample injection unit feedback information.
The sample introduction stirring hand unit, which is used to push positioned at the reagent card article of optocoupler position, to be incubated in unit.
The incubation unit is used to be incubated reagent card article, and when incubation time arrives, reagent card article is moved into inspection
Survey above unit.
The censorship stirring hand unit is used to toggle it to reagent card article in detection unit.
The data that the detection unit is used on reading reagent card article.
Preferably：The sample injection unit includes sample introduction tank, the first locating fastener, the first lead screw motor, the first screw mandrel, first
Line slideway, sample introduction fagging and the first sliding block, first lead screw motor, first straight line guide rail are fixedly mounted on workbench
On, and first sliding block is arranged on first straight line guide rail, and first sliding block is slidably connected with first straight line guide rail, institute
State sample introduction fagging one end and the first sliding block is affixed, the other end is affixed with sample introduction tank.The sample introduction fagging is provided with and the first screw mandrel
The mounting hole of the first nut to match, the first nut are arranged on sample introduction fagging, described first screw mandrel one end and the first nut
Connection, the other end and the first lead screw motor driving axis connection.First locating fastener is arranged in sample introduction tank, and described first
Locating fastener is used for and the screens clamping on reagent card article.The light for the insertion of identification agent card article is provided with the sample introduction tank
Electric transducer.
Preferably：The sample introduction stirring hand unit includes second straight line guide rail, the second sliding block, stopper slot, sample introduction stirring hand, torsion
Block, spring retainer bar, the 3rd line slideway, the second stepper motor, the second timing belt, second stepper motor, second straight line
Guide rail is respectively mounted on the table, and second sliding block is arranged on second straight line guide rail, and second sliding block and second
Line slideway is slidably connected, and the 3rd line slideway, spring retainer bar are installed on the second sliding block, and the sample introduction stirring hand
On the 3rd line slideway, and the sample introduction stirring hand is slidably connected with the 3rd line slideway, at the same the sample introduction stirring hand with
Spring connection on spring retainer bar.The torsion block is installed on the table, and the torsion block is set along second straight line guide rail, and
The stopper slot is between torsion block and workbench.Second sliding block is synchronous with the second timing belt fixed, and the second step
Stepper motor is connected with the second toothed belt transmission.
Preferably：3rd line slideway, spring retainer bar are perpendicular with second straight line guide rail.
Preferably：The incubation unit includes incubating groove, the 4th line slideway, the 3rd timing belt, the 4th stepper motor, institute
State the 4th stepper motor, the installation of the 4th line slideway on the table, the incubation groove is arranged on the 4th line slideway, and institute
Incubation groove is stated to be slidably connected with the 4th line slideway, while the incubation groove is synchronous with the 3rd timing belt fixed, and the described 4th
Stepper motor is connected with the 3rd toothed belt transmission.
Preferably：The bulb plunger for installing location reagent card article is provided with the incubation groove.
Preferably：It is provided with the incubation groove for the heating plate for incubating groove heating.
Preferably：The temperature sensor that temperature in groove is incubated for measuring is provided with the incubation groove.
Preferably：The censorship stirring hand unit includes censorship stirring hand, the 4th timing belt, the 5th stepper motor, the 5th straight line
Guide rail, on the table, the censorship stirring hand is arranged at the 5th straight line and led for the 5th stepper motor, the installation of the 5th line slideway
On rail, and the censorship stirring hand is slidably connected with the 5th line slideway, and the censorship stirring hand is synchronous with the 4th timing belt fixed, and
5th stepper motor is connected with the 4th toothed belt transmission.
Preferably：The detection unit include light path, the 6th line slideway, the 6th sliding block, light path fagging, second
Bar motor, the second screw mandrel, detect tank, the 6th line slideway, the second lead screw motor, detect tank are fixedly mounted on work and put down
On platform, the 6th sliding block is arranged on the 6th line slideway, and the 6th sliding block is slidably connected with the 6th line slideway, institute
State light path to be fixedly connected with the 6th sliding block, and the light path is located at the top of detect tank, and it is fixed that second is provided with the detect tank
Position buckle, second locating fastener are used for and the screens clamping on reagent card article.
The present invention compared with prior art, has the advantages that：
The present invention uses integrated design, integrates multiple functions, it is possible to achieve multisample incubates simultaneously, one by one sample
Detection, greatly improves checkability, the standardization, automation and precision of multichannel immunofluorescence instrument is further changed
It is kind.
Brief description of the drawings
Fig. 1 is the structural representation of the present invention；
Fig. 2 is sample injection unit structural representation；
Fig. 3 is sample introduction stirring hand cellular construction schematic diagram；
Fig. 4 is incubation cellular construction schematic diagram；
Fig. 5 is censorship stirring hand cellular construction schematic diagram；
Fig. 6 is detection unit structural representation.
Wherein, 1 is sample injection unit, and 1-1 is sample introduction tank, and 1-2 is the first locating fastener, and 1-3 is the first lead screw motor, 1-4
For first straight line guide rail, 1-5 is sample introduction fagging, and 2 be bar code scanner, and 3 be sample introduction stirring hand unit, and 3-1 leads for second straight line
Rail, 3-2 are stopper slot, and 3-3 is sample introduction stirring hand, and for 3-4 to turn round block, 3-5 is spring retainer bar, and 3-6 is the 3rd line slideway, 3-7
For the second stepper motor, 3-8 is the second timing belt, and 4 is incubate unit, and for 4-1 to incubate groove, 4-2 is bulb plunger, 4-3 the
Four line slideways, 4-4 are the 3rd timing belt, and 4-5 is the 4th stepper motor, and 5 be censorship stirring hand unit, and 5-1 is censorship stirring hand, 5-
2 be the 4th timing belt, and 5-3 is the 5th stepper motor, and 5-4 is the 5th line slideway, and 6 be detection unit, and 6-1 is light path, and 6-2 is
6th line slideway, 6-3 are light path fagging, and 6-4 is the second lead screw motor, and 6-5 is detect tank.
Embodiment
Below in conjunction with the accompanying drawings and specific embodiment, the present invention is furture elucidated, it should be understood that these examples are merely to illustrate this
Invention rather than limitation the scope of the present invention, after the present invention has been read, those skilled in the art are various to the present invention's
The modification of the equivalent form of value falls within the application appended claims limited range.
A kind of multichannel Immunofluorescence test device, as shown in figure 1, including installing sample injection unit 1 on the table, bar
Code scanner 2, sample introduction stirring hand unit 3, unit 4, censorship stirring hand unit 5, detection unit 6 are incubated, wherein：
The sample injection unit 1 is used to insert reagent card article, and the insertion situation of detection reagent card article, while will detect
Insertion situation is sent to bar code scanner 2.
As shown in Fig. 2 the sample injection unit 1 include sample introduction tank 1-1, the first locating fastener 1-2, the first lead screw motor 1-3,
First screw mandrel, first straight line guide rail 1-4, sample introduction fagging 1-5 and the first sliding block, the first lead screw motor 1-3, first straight line
Guide rail 1-4 is fixedly mounted on the table, and first sliding block is arranged on first straight line guide rail 1-4, and described first slides
Block is slidably connected with first straight line guide rail 1-4, and described sample introduction fagging 1-5 one end and the first sliding block are affixed, the other end and sample introduction tank
1-1 is affixed.The sample introduction fagging 1-5 is provided with the mounting hole of the first nut to match with the first screw mandrel, the installation of the first nut
On sample introduction fagging (1-5), described first screw mandrel one end is connected with the first nut, and the other end and the first lead screw motor 1-3 drive
Axis connection.The first locating fastener 1-2 is arranged on sample introduction tank 1-1, and the first locating fastener 1-2 is used for and reagent card
Screens clamping on bar.The photoelectric sensor for the insertion of identification agent card article is provided with the sample introduction tank 1-1.
The bar code scanner 2 is used for the signal according to photoelectric sensor transmission to the reagent card article in sample introduction tank 1-1
On bar code be read out, then send instructions to automatic sampling gun, automatic sampling gun sets sample-adding amount automatically, to reagent card
Sample is added in bar, adds after sample automatic sampling gun to the feedback information of sample injection unit 1.
The sample introduction stirring hand unit 3, which is used to push positioned at the reagent card article of optocoupler position, to be incubated in unit 4.
As shown in figure 3, the sample introduction stirring hand unit 3 includes second straight line guide rail 3-1, the second sliding block, stopper slot 3-2, entered
Sample stirring hand 3-3, turn round block 3-4, spring retainer bar 3-5, the 3rd line slideway 3-6, the second stepper motor 3-7, the second timing belt 3-
8, the second stepper motor 3-7, second straight line guide rail 3-1 are respectively mounted on the table, and second sliding block is arranged on the
On two line slideway 3-1, and second sliding block is slidably connected with second straight line guide rail 3-1, the 3rd line slideway 3-6,
Spring retainer bar 3-5 is installed on the second sliding block, and the sample introduction stirring hand 3-3 is arranged on the 3rd line slideway 3-6, and institute
Sample introduction stirring hand 3-3 and the 3rd line slideway 3-6 is stated to be slidably connected, while on the sample introduction stirring hand 3-3 and spring retainer bar 3-5
Spring connects.The torsion block 3-4 is installed on the table, and the torsion block 3-4 is set along second straight line guide rail 3-1, and described
Stopper slot 3-2 is between torsion block 3-4 and workbench.Second sliding block is synchronous with the second timing belt 3-8 fixed, and described the
Two stepping motor 3-7 and the second timing belt 3-8 is connected.The 3rd line slideway 3-6, spring retainer bar 3-5 are with
Two line slideway 3-1 are perpendicular.
The incubation unit 4 is used to be incubated reagent card article, and when incubation time arrives, reagent card article is moved into inspection
Survey the top of unit 6.
As shown in figure 4, the incubation unit 4 includes incubating groove 4-1, the 4th line slideway 4-3, the 3rd timing belt 4-4, the
Four stepper motor 4-5, the 4th stepper motor 4-5, the 4th line slideway 4-3 are installed on the table, described to incubate groove 4-1
It is arranged on the 4th line slideway 4-3, and incubation groove 4-1 and the 4th line slideway 4-3 is slidably connected, while the incubation
Groove 4-1 is synchronous with the 3rd timing belt 4-4 fixed, and the 4th stepper motor 4-5 and the 3rd timing belt 4-4 is connected.Institute
The number for stating incubation groove 4-1 is more than one, and the number of the present embodiment is 8.It is provided with the incubation groove 4-1 for installing
The bulb plunger 4-2 of location reagent card article.Described incubate is provided with groove 4-1 for the heating plate for incubating groove heating.It is described
Incubate the temperature sensor for being provided with groove 4-1 and temperature in groove being incubated for measuring.
The censorship stirring hand unit 5 is used to toggle it to reagent card article in detection unit 6.
As shown in figure 5, the censorship stirring hand unit 5 includes censorship stirring hand 5-1, the 4th timing belt 5-2, the 5th stepper motor
5-3, the 5th line slideway 5-4, the 5th stepper motor 5-3, the 5th line slideway 5-4 are installed on the table, described to send
Inspection stirring hand 5-1 is arranged on the 5th line slideway 5-4, and the censorship stirring hand 5-1 and the 5th line slideway 5-4 is slidably connected,
The censorship stirring hand 5-1 is synchronous with the 4th timing belt 5-2 fixed, and the 5th stepper motor 5-3 and the 4th timing belt 5-2 is passed
Dynamic connection.
The data that the detection unit 6 is used on reading reagent card article.
As shown in fig. 6, the detection unit 6 includes light path 6-1, the 6th line slideway 6-2, the 6th sliding block, light path
Fagging 6-3, the second lead screw motor 6-4, the second screw mandrel, detect tank 6-5, the 6th line slideway 6-2, the second lead screw motor 6-
4th, detect tank 6-5 is fixedly mounted on workbench, and the 6th sliding block is arranged on the 6th line slideway 6-2, and described
6th sliding block is slidably connected with the 6th line slideway 6-2, and the light path 6-1 is fixedly connected with the 6th sliding block, and the light path 6-1
Positioned at detect tank 6-5 top, be provided with the second locating fastener on the detect tank 6-5, second locating fastener be used for
Screens clamping on reagent card article.
When starting detection, the first lead screw motor 1-3 drives sample introduction fagging 1-5 to move forward, and sample introduction fagging 1-5 and first is straight
The first sliding block, sample introduction tank 1-1 on line guide rail 1-4 are fixed together, and the first sliding block on first straight line guide rail 1-4 fixes sample introduction
Groove 1-1 will not be rocked, sample introduction tank 1-1 in-positions, reagent card article be inserted, when reagent card article is inserted into position, on reagent card article
The first locating fastener 1-2 in screens and sample introduction tank 1-1 is just positioned.Reflective photoelectric sensor in sample introduction tank 1-1 is known
It is clipped to and inserts reagent card article, the bar code on the reading reagent card article of bar code scanner 2, then sends instructions to automatic sample
Rifle, automatic sampling gun set sample-adding amount automatically, and sample is added into reagent card article.After adding sample, automatic sampling gun is by information
The first lead screw motor 1-3 is fed back to, the first lead screw motor 1-3 drives sample introduction tank 1-1 to be moved rearwards, when reaching optocoupler position,
Stop motion.
The second stepper motor 3-7 rotations on sample introduction stirring hand unit 3, drive the second timing belt 3-8 motions, sample introduction stirring hand 3-
3 and second timing belt 3-8 fix, so as to drive sample introduction stirring hand 3-3 to travel forward, after stopper slot 3-2 leading portions are moved to, spring
Gag lever post 3-5 is dropped in stopper slot 3-2, and at this moment sample introduction stirring hand 3-3 can just push reagent card article, sample introduction stirring hand 3-3 handles
Reagent card article, which pushes, to be incubated in groove 4-1.
Incubating in device has bulb plunger 4-2, the flexible effect of bulb plunger, can position reagent card article, so
Reagent card article will not be moved incubating in groove 4-1.Incubating below groove 4-1 has heating plate, to groove heating is incubated, incubates in groove
There is temperature sensor, control incubates groove constant temperature.When incubation time arrives, the 4th stepper motor 4-5 rotating bands on unit are incubated
Dynamic 3rd timing belt 4-4 is moved, and the attachment means on the 3rd timing belt 4-4 relatively connect incubation groove 4-1 and the 3rd timing belt 4-4
Connect, groove 4-1 movements are incubated so as to drive, when incubation groove 4-1 positions reach the detect tank 6-5 positions of detection unit, incubate unit and stop
Only move.
The 5th stepper motor 5-3 rotates on censorship stirring hand unit, the 4th timing belt 5-2 motions is driven, so as to drive censorship
Stirring hand 5-1 is moved, and reagent card article is sent to detect tank 6-5 by censorship stirring hand 5-1.
When the second locating fastener in the screens on reagent card article and detect tank 6-5 is just positioned, censorship stirring hand 5-1 to
Reverse back to initial bit.The second lead screw motor 6-4 in detection unit drives light path 6-1 to move, on reading reagent card article
Data.Previous card article is released when next detection card article censorship.
The present invention fixes the stability for ensureing sample introduction tank by the first sliding block on first straight line guide rail, avoids rocking.Bar
Code scanner can effectively identify project and measure content, avoid the confusion of sample by the bar code on reading reagent card article.
The information reflected according to reagent card bar bar code, multichannel immunofluorescence analysis instrument send instructions to automatic sampling gun, automatic sample
Rifle can be adjusted to be loaded range automatically, reduce manual operation, can reduce the operating procedure and workload of experimenter, can reduce again
Mistake probability, make testing result more accurate.Reagent card article is fixed in the presence of bulb plunger to be incubated in groove, is realized multiple
Constant temperature is incubated reagent card article simultaneously, and management and control is carried out to the temperature of test sample, it is ensured that reacted under optimal temperature environment,
Improve the accuracy of detection of equipment.After reaching incubative time, multichannel immunofluorescence analysis instrument reads examination by detection means one by one
Data on agent card article, previous card article is released when next detection card article censorship, realize and continuously detect, and can subtract
Few human users' step.
The present invention uses integrated design, compact-sized, can rapidly analyze a series of, big batch testing sample, and
Testing result reliability, stability are high, and speed is fast, and sensitivity is good.Reduce the operating procedure of experimenter, improve sample point
While analysing efficiency, it is avoided that sample contamination and sample information are chaotic.The multichannel immunofluorescence analysis instrument may be used on clinic
In detection, qualitative, quantitative foundation is provided for clinical treatment.
Described above is only the preferred embodiment of the present invention, it should be pointed out that：For the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
- A kind of 1. multichannel Immunofluorescence test device, it is characterised in that：Including install sample injection unit (1) on the table, Bar code scanner (2), sample introduction stirring hand unit (3), unit (4), censorship stirring hand unit (5), detection unit (6) are incubated, wherein：The sample injection unit (1) is used to insert reagent card article, and the insertion situation of detection reagent card article, while is inserted what is detected Enter situation and be sent to bar code scanner (2)；The bar code scanner (2) is used for the signal according to photoelectric sensor transmission to the reagent card article in sample introduction tank (1-1) On bar code be read out, then send instructions to automatic sampling gun, automatic sampling gun sets sample-adding amount automatically, to reagent card Sample is added in bar, adds after sample automatic sampling gun to sample injection unit (1) feedback information；The sample introduction stirring hand unit (3), which is used to push the reagent card article positioned at optocoupler position, to be incubated in unit (4)；The incubation unit (4) is used to be incubated reagent card article, and when incubation time arrives, reagent card article is moved into detection In unit (6)；The censorship stirring hand unit (5) is used to toggle it to reagent card article in detection unit (6)；The data that the detection unit (6) is used on reading reagent card article.
- 2. multichannel Immunofluorescence test device according to claim 1, it is characterised in that：The sample injection unit (1) includes Sample introduction tank (1-1), the first locating fastener (1-2), the first lead screw motor (1-3), first straight line guide rail (1-4), sample introduction fagging (1- 5) and the first sliding block, first lead screw motor (1-3), first straight line guide rail (1-4) are fixedly mounted on the table, and institute The first sliding block is stated on first straight line guide rail (1-4), and first sliding block is slided with first straight line guide rail (1-4) and connected Connect, described sample introduction fagging (1-5) one end and the first sliding block are affixed, and the other end and sample introduction tank (1-1) are affixed；The sample introduction fagging (1-5) is provided with the mounting hole of the first nut to match with the first screw mandrel, and the first nut is arranged on sample introduction fagging (1-5), Described first screw mandrel one end is connected with the first nut, the other end and the first lead screw motor (1-3) driving axis connection；Described first is fixed Position buckle (1-2) is arranged in sample introduction tank (1-1), and first locating fastener (1-2) is used for and the screens on reagent card article Clamping；The photoelectric sensor for the insertion of identification agent card article is provided with the sample introduction tank (1-1).
- 3. multichannel Immunofluorescence test device according to claim 1, it is characterised in that：The sample introduction stirring hand unit (3) Including second straight line guide rail (3-1), the second sliding block, stopper slot (3-2), sample introduction stirring hand (3-3), torsion block (3-4), spring retainer bar (3-5), the 3rd line slideway (3-6), the second stepper motor (3-7), the second timing belt (3-8), the second stepper motor (3- 7), second straight line guide rail (3-1) is respectively mounted on the table, and second sliding block is arranged on second straight line guide rail (3-1), And second sliding block is slidably connected with second straight line guide rail (3-1), the 3rd line slideway (3-6), spring retainer bar (3- 5) it is installed on the second sliding block, and the sample introduction stirring hand (3-3) is arranged on the 3rd line slideway (3-6), and the sample introduction Stirring hand (3-3) is slidably connected with the 3rd line slideway (3-6), while on the sample introduction stirring hand (3-3) and spring retainer bar (3-5) Spring connection；The torsion block (3-4) is installed on the table, and the torsion block (3-4) sets along second straight line guide rail (3-1) Put, and the stopper slot (3-2) is located at torsion block (3-4) between workbench；Second sliding block and the second timing belt (3-8) are same Step is fixed, and second stepper motor (3-7) is connected with the second timing belt (3-8).
- 4. multichannel Immunofluorescence test device according to claim 3, it is characterised in that：3rd line slideway (the 3- 6), spring retainer bar (3-5) is perpendicular with second straight line guide rail (3-1).
- 5. multichannel Immunofluorescence test device according to claim 1, it is characterised in that：The incubation unit (4) includes Incubate groove (4-1), the 4th line slideway (4-3), the 3rd timing belt (4-4), the 4th stepper motor (4-5), the 4th stepping On the table, the incubation groove (4-1) is arranged at the 4th line slideway for motor (4-5), the installation of the 4th line slideway (4-3) On (4-3), and the incubation groove (4-1) is slidably connected with the 4th line slideway (4-3), while the incubation groove (4-1) and the Three timing belts (4-4) are synchronously fixed, and the 4th stepper motor (4-5) is connected with the 3rd timing belt (4-4).
- 6. multichannel Immunofluorescence test device according to claim 5, it is characterised in that：Set in the incubation groove (4-1) It is equipped with the bulb plunger (4-2) for installing location reagent card article.
- 7. multichannel Immunofluorescence test device according to claim 5, it is characterised in that：Set in the incubation groove (4-1) It is equipped with for the heating plate for incubating groove heating.
- 8. multichannel Immunofluorescence test device according to claim 5, it is characterised in that：Set in the incubation groove (4-1) It is equipped with the temperature sensor that temperature in groove is incubated for measuring.
- 9. multichannel Immunofluorescence test device according to claim 1, it is characterised in that：The censorship stirring hand unit (5) Including censorship stirring hand (5-1), the 4th timing belt (5-2), the 5th stepper motor (5-3), the 5th line slideway (5-4), described On the table, it is straight that the censorship stirring hand (5-1) is arranged at the 5th for five stepper motors (5-3), the installation of the 5th line slideway (5-4) On line guide rail (5-4), and the censorship stirring hand (5-1) is slidably connected with the 5th line slideway (5-4), the censorship stirring hand (5- 1) it is synchronous with the 4th timing belt (5-2) fixed, and the 5th stepper motor (5-3) is connected with the 4th timing belt (5-2).
- 10. multichannel Immunofluorescence test device according to claim 1, it is characterised in that：The detection unit (6) includes Light path (6-1), the 6th line slideway (6-2), the 6th sliding block, light path fagging (6-3), the second lead screw motor (6-4), second Screw mandrel, detect tank (6-5), the fixed peace of the 6th line slideway (6-2), the second lead screw motor (6-4), detect tank (6-5) On workbench, the 6th sliding block is arranged on the 6th line slideway (6-2), and the 6th sliding block and the 6th straight line Guide rail (6-2) is slidably connected, and the light path (6-1) is fixedly connected with the 6th sliding block, and the light path (6-1) is located at detect tank The top of (6-5), the second locating fastener is provided with the detect tank (6-5), second locating fastener is used for and reagent card Screens clamping on bar.
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| CN201710650606.3A CN107490703A (en) | 2017-08-02 | 2017-08-02 | A kind of multichannel Immunofluorescence test device |
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| CN201710650606.3A CN107490703A (en) | 2017-08-02 | 2017-08-02 | A kind of multichannel Immunofluorescence test device |
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| CN110007069A (en) * | 2019-03-05 | 2019-07-12 | 深圳迎凯生物科技有限公司 | Fluorescence immunoassay tester |
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