CN105866452A - Multi-channel dry type immunofluorescence detector - Google Patents
Multi-channel dry type immunofluorescence detector Download PDFInfo
- Publication number
- CN105866452A CN105866452A CN201610351351.6A CN201610351351A CN105866452A CN 105866452 A CN105866452 A CN 105866452A CN 201610351351 A CN201610351351 A CN 201610351351A CN 105866452 A CN105866452 A CN 105866452A
- Authority
- CN
- China
- Prior art keywords
- card
- unit
- stirring
- motor
- shaft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00207—Handling bulk quantities of analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The invention relates to a multi-channel dry type immunofluorescence detector which comprises a mounting platform. An incubation rotary disc, an automatic card inlet unit, an automatic measuring unit and an automatic card outlet unit are mounted on the right side of the mounting platform. A mounting plate is mounted above the incubation rotary disc. The automatic card inlet unit, the automatic measuring unit and the automatic card outlet unit are mounted on the mounting plate. A sample adding unit and a sample and reagent unit are arranged on the left side of the mounting platform. The multi-channel dry type immunofluorescence detector has the advantages of being high in speed, high in efficiency, capable of carrying out multi-channel mass detection and high in precision.
Description
Technical field
The present invention relates to detect equipment technical field, particularly relate to a kind of multichannel dry type Immunofluorescence test instrument.
Background technology
In modern medicine inspection fluorometric investigation system, using the excitation measured object of special wavelength, measured object is subject to
After the photon excitation of special wavelength, there is energy jump, launch the photon of special wavelength, measure the intensity of transition light, thus
The number of measured object content can be obtained.Existing fluorescence detector exists that detection speed is slow, can not enter by automated multi-channel continuously
The shortcoming of row detection, and testing result can not carry out correspondence by automatic numbering, easily obscures, for large hospital, every day
Substantial amounts of Detection task, needs to purchase the expensive equipment of multiple stage, multiple testing staff detects, and not only adds and detects into
This, to add labour intensity, detection efficiency low, and patient also to wait until second day or the 3rd day just to take testing result,
Easily delay treatment.Invent a detection speed be fast, detection efficiency is high, can automatic numbering, automatically enter card, automatic card release, automatically examine
Survey, can high-volume multichannel carry out detection analyze fluorescence detector be the task of top priority.
Summary of the invention
The invention aims to overcome the deficiencies in the prior art, it is provided that a kind of novel multi-channel dry type immunofluorescence inspection
Survey instrument.
The present invention is achieved by the following technical programs:
A kind of multichannel dry type Immunofluorescence test instrument, including mounting platform, hatch rotating disk, installing plate, automatically enter card unit, from
Dynamic measuring unit, automatic card release unit, the right side of described mounting platform is provided with hatches rotating disk, described in hatch rotating disk installed above
There is installing plate, described installing plate is provided with and automatically enters card unit, automatic measuring unit, automatic card release unit.
Described automatically enter card unit and include chart feeder frame, screw mandrel, card fixture, shaft coupling, enter card motor, described chart feeder
Frame is fixing, and described chart feeder frame is provided with screw mandrel on a mounting board, and described card fixture is arranged on screw mandrel and can come along screw mandrel
Backhauling dynamic, described screw mandrel right-hand member is connected with entering card motor by shaft coupling.
Described automatic measuring unit include fluorescence signal acquisition device, measure motor, to measure driving wheel, belt, measurement driven
Wheel, driven carriage, motion guide rail, described motion guide rail, measurement driven carriage and measurement motor are respectively mounted on a mounting board, described
Measuring and be provided with a driving wheel on the output shaft of motor, described measurement driving wheel is connected to measure driven pulley, institute by belt
State measurement driven pulley to be arranged on driven carriage, described belt is provided with fluorescence signal acquisition device.
Described automatic card release unit includes card release push pedal, card release motor, the first synchronous pulley, the second synchronous pulley, synchronization
Band, described card release motor is installed on a mounting board, equipped with the first synchronous pulley on the output shaft of described card release motor, described first
Synchronous pulley is connected by Timing Belt and the second synchronous pulley, and described Timing Belt is provided with card release push pedal.
Further, the described card fixture automatically entered in card unit uses elastic force backstop, described elastic force backstop bag
Including mounting seat, feed screw nut, rotating shaft, spin locking fixture, spinning reduction spring, described mounting seat top is provided with feed screw nut,
Described feed screw nut and big screw lead Thread cooperatively form screw pair, and the lower left quarter of described mounting seat is provided with rotating shaft, in described rotating shaft
Equipped with spin locking fixture, described spin locking fixture can rotate around the shaft, and described spin locking fixture is provided with spinning reduction
Spring, described spinning reduction spring one end is connected with spin locking fixture, the described spinning reduction spring other end and mounting seat phase
Even.
Further, described spin locking fixture includes sticking up bar, chuck body, latch hook, axis hole, described in stick up bar and be arranged on folder
The upper left side of tool body, described chuck body is provided with axis hole, and described axis hole cooperatively forms revolute pair with the rotating shaft in mounting seat,
The bottom of described chuck body is provided with latch hook, and the locating slot of described latch hook depression upper with test card matches.
Further, the fluorescence signal acquisition device in described automatic measuring unit includes packaging cartridge, data-interface, laser strip
Code identification module, signal measurement module, excitation source module, described packaging cartridge upper right side is provided with data-interface, and described data connect
Mouth transmits for data, and described packaging cartridge has been internally integrated laser bar code identification module, signal measurement module, excitation source mould
Block.
Further, described in hatch rotating disk and be provided with the draw-in groove being evenly arranged, described in hatch the center of rotating disk and be provided with rotation
Axle, described rotary shaft bottom is provided with electric rotating machine, and described rotary shaft is provided with location dish, and described location dish side is provided with measurement
The angular transducer of the anglec of rotation.
Further, described multichannel dry type Immunofluorescence test instrument is provided with sample-adding unit in the left side of mounting platform.
Further, described sample-adding unit includes frame, upright guide rail, slide block, collision detection sheet, photoelectric sensor, liter
Fall Timing Belt, lifting motor, clutch shaft bearing, main shaft, code-disc, angular transducer, rotation wheel, rotation synchronization belt, electric rotating machine, pendulum
Arm, sample needle, the front of described frame is provided with upright guide rail, and described upright guide rail is provided with the slide block that can slide up and down, institute
Stating and be provided with Photoelectric Detection sheet on the left of slide block, the side of described frame is equipped with being used for detecting the photoelectric sensor of Photoelectric Detection sheet, institute
Stating and be fixedly mounted on the right side of slide block on lifting Timing Belt, described lifting Timing Belt is connected with lifting motor, described its center position
Putting and be provided with clutch shaft bearing, the lower end of described main shaft is arranged in clutch shaft bearing, and the middle part of described main shaft is provided with code-disc and rotation
Runner, is provided with the angular transducer for detecting code-disc rotational angle above or below described code-disc, described rotation wheel passes through
Rotation synchronization belt is connected with electric rotating machine, and the top of described main shaft is fixedly linked with one end of swing arm, the other end of described swing arm
It is provided with sample needle.
Further, described swing arm being additionally provided with stirring anti-collision unit, described stirring anti-collision unit includes compression spring, gear
Plate, crashproof cover, striker, collision detection sheet, crashproof detection grating, the second bearing, stirring motor, stirring driving wheel, stirring synchronize
Band and stirring driven pulley, one end of described swing arm is provided with the second bearing, is provided with sample needle, described sample-adding in described second bearing
Pin top is connected with compression spring one end, and the described compression spring other end connects has baffle plate, described baffle plate to be arranged in crashproof cover,
All having through hole on described baffle plate and crashproof cover, described sample needle is connected through through hole with the striker being positioned at crashproof cover top, institute
Stating striker and be provided with collision detection sheet, described collision detection sheet side is provided with crashproof detection grating；Described swing arm is at crashproof cover
Side is provided with stirring motor, and the output shaft of described stirring motor is connected through swing arm with stirring driving wheel, and described sample needle is leaning on
Being provided with stirring driven pulley at nearly second bearing, described stirring driven pulley is connected with stirring driving wheel by stirring Timing Belt.
Further, described multichannel dry type Immunofluorescence test instrument is also equipped with sample and examination in the left side of mounting platform
Agent unit.
Further, described mounting platform is additionally provided with display screen, controls mainboard, printer.
The technique effect of the present invention is as follows:
The present invention uses rotary being automatically positioned to hatch rotating disk, swing arm Anti-collision sample-adding unit, automatically enter card unit, automatically measure
Unit, automatic card release unit, can be automatically performed from sampling, enter card, detect, encode, analyze, store, move back a series of actions such as card,
Can realize high-volume test card Automatic continuous detection analyze, have simple in construction, volume compact, speed is fast, efficiency is high, can be many
Passage detects in a large number, accuracy high, the advantage of the detection time that uses manpower and material resources sparingly, shortens, and solves existing detector detection speed
Degree is slow, automaticity is low, easily obscure, detect time length, testing result out slowly, the problem such as personnel depaly is many.The present invention
Also there is the functions such as sampling probe crashproof, liquid level accurately controls, automatic alarm.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention 1.
Fig. 2 is the structural representation of the embodiment of the present invention 2.
Fig. 3 is the structural representation automatically entering card unit.
Fig. 4 is the structural representation of elastic force backstop.
Fig. 5 is the structural representation of automatic measuring unit.
Fig. 6 is the structural representation of fluorescence signal acquisition device.
Fig. 7 is the structural representation of automatic card release unit.
Fig. 8 is the structural representation of sample-adding unit.
Fig. 9 is the structural representation of stirring anti-collision unit.
In accompanying drawing, 1 mounting platform, 2 hatch rotating disk, 201 draw-in grooves, 202 rotary shafts, 3 installing plates,
4 enter card unit automatically, 401 chart feeder framves, 402 screw mandrels, 403 card fixtures, 404 shaft couplings, and 405
Entering card motor, 406 mounting seats, 407 feed screw nuts, 408 stick up bar, 409 rotating shafts, 410 chuck body,
411 spinning reduction springs, 412 latch hooks, 5 automatic measuring units, 501 mounting bases, 502 motion guide rails,
503 measurement motors, 504 driven carriage, 505 driven pulleys, 506 fluorescence signal acquisition devices, 507 belts,
508 driving wheels, 509 data-interfaces, 510 laser vias, 511 packaging cartridges, 512 LED light sources, 513
Collimating lens, 514 exciting light optical filters, 515 two-phase dichronic mirrors, 516 first convex lens, 517 measured objects
Target unit, 518 transition light optical filters, 519 second convex lens, 520 gratings, 521 Transition Spectra receivers,
522 laser generators, 523 second collimation lenses, 524 bar code colour bands, 525 numbering collectors, 6 go out automatically
Card unit, 601 card release motors, 602 first synchronous pulleys, 603 second synchronous pulleys, 604 Timing Belts,
605 card release push pedals, 7 sample-adding unit, 701 frames, 702 upright guide rails, 703 Photoelectric Detection sheets, 704
Photoelectric sensor, 705 slide blocks, 706 clutch shaft bearings, 707 lifting Timing Belts, 708 angular transducers, 709
Rotate wheel, 710 rotation synchronization belt, 711 electric rotating machines, 712 main shafts, 713 detecting liquid level modules, 714 pendulum
Arm, 715 stirring anti-collision units, 716 sample needles, 717 code-discs, 718 lifting motors, 719 stirring motors,
720 crashproof detection gratings, 721 collision detection sheets, 722 strikers, 723 crashproof covers, 724 baffle plates, 725
Compression spring, 726 second bearings, 727 stirring driven pulleys, 728 stirring Timing Belts, 729 stirring driving wheels,
8 samples and reagent unit, 9 printers, 10 control mainboard, 11 display screens, 12 test cards.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in further detail.
Embodiment 1
With reference to Fig. 1, a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform 1, hatch rotating disk 2, installing plate 3, automatically
Entering card unit 4, automatic measuring unit 5, automatic card release unit 6, described mounting platform 1 is provided with hatches rotating disk 2, described in hatch turn
Dish 2 is provided with the draw-in groove 201 being evenly arranged, and described draw-in groove 201 is used for installing test card 12, and draw-in groove 201 is along hatching the half of rotating disk 2
Direction, footpath is evenly arranged.The center hatching rotating disk 2 is provided with rotary shaft 202, and described rotary shaft 202 is arranged on mounting platform 1, institute
State and hatch rotating disk 2 and can rotate along rotary shaft 202.Hatch rotating disk 2 and be arranged above installing plate 3, described installing plate 3 is provided with certainly
Move into card unit 4, automatic measuring unit 5, automatic card release unit 6.
With reference to Fig. 3, described automatically enter card unit 4 and include chart feeder frame 401, screw mandrel 402, card fixture 403, shaft coupling
404, entering card motor 405, described chart feeder frame 401 is fixed on installing plate 3, and described chart feeder frame 401 is provided with screw mandrel 402,
Described card fixture 403 is arranged on screw mandrel 402 and can move back and forth along screw mandrel 402, and described screw mandrel 402 right-hand member passes through shaft coupling
404 are connected with entering card motor 405.
With reference to Fig. 5, described automatic measuring unit 5 includes fluorescence signal acquisition device 506, measures motor 503, measurement driving wheel
508, belt 507, measure driven pulley 505, driven carriage 504, motion guide rail 502, described motion guide rail 502, measure driven
Frame 504 and measurement motor 503 are installed on installing plate 3, and the output shaft of described measurement motor 503 is provided with a driving wheel
508, described measurement driving wheel 508 is connected to measure driven pulley 505 by belt 507, described measurement driven pulley 505 be arranged on from
On dynamic support 504, described belt 507 is provided with fluorescence signal acquisition device 506.
With reference to Fig. 6, described automatic card release unit 6 include card release push pedal 605, card release motor the 601, first synchronous pulley 602,
Second synchronous pulley 603, Timing Belt 604, described card release motor 601 is arranged on installing plate 3, described card release motor 601 defeated
Equipped with the first synchronous pulley 602 on shaft, described first synchronous pulley 602 is by Timing Belt 604 and the second synchronous pulley 603 phase
Even, described Timing Belt 604 is provided with card release push pedal 605.When needs card release, card release motor 601 starts, and drives Timing Belt
604 motions, thus drive the card release push pedal 605 being arranged on Timing Belt 604 by test card 12 from the draw-in groove 201 hatching rotating disk 2
Middle release.
Embodiment 2
With reference to Fig. 2, a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform 1, hatch rotating disk 2, installing plate 3, automatically
Enter card unit 4, automatic measuring unit 5, automatic card release unit 6.The left side of described mounting platform 1 is provided with sample-adding unit 7, described peace
The right side of assembling platform 1 is provided with hatches rotating disk 2, described in hatch rotating disk 2 and be provided with the draw-in groove 201 being evenly arranged, described in hatch and turn
The center of dish 2 is provided with rotary shaft 202, and described rotary shaft 202 bottom is provided with driving motor, and described rotary shaft 202 is provided with fixed
Position dish, described location dish side is provided with the sensor measuring the anglec of rotation.Hatch rotating disk 2 and be arranged above installing plate 3, described peace
It is provided with on dress plate 3 and automatically enters card unit 4, automatic measuring unit 5, automatic card release unit 6.
With reference to Fig. 3, automatically enter card unit 4 and include chart feeder frame 401, screw mandrel 402, card fixture 403, shaft coupling 404, enter
Card motor 405, described chart feeder frame 401 is fixed on installing plate 3, and described chart feeder frame 401 is provided with screw mandrel 402, described card
Plate clamp 403 is arranged on screw mandrel 402 and can move back and forth along screw mandrel 402, described screw mandrel 402 right-hand member by shaft coupling 404 with
Enter card motor 405 to be connected.
With reference to Fig. 4, automatically enter the card fixture 403 in card unit 4 and use elastic force backstop, described elastic force backstop to include
Mounting seat 406, feed screw nut 407, rotating shaft 409, spin locking fixture, spinning reduction spring 411, described mounting seat 406 top
Being provided with feed screw nut 407, it is secondary that described feed screw nut 407 and big screw lead Thread 402 cooperatively form screw mandrel 402, described mounting seat 406
Lower left quarter be provided with rotating shaft 409, equipped with spin locking fixture in described rotating shaft 409, described spin locking fixture can around the shaft 409
Rotating, described spin locking fixture is provided with spinning reduction spring 411, described spinning reduction spring 411 one end and spin locking
Fixture is connected, and described spinning reduction spring 411 other end is connected with mounting seat 406.
Described spin locking fixture includes sticking up bar 408, chuck body 410, latch hook 412, axis hole, described in stick up bar 408 and install
On the upper left side of chuck body 410, described chuck body 410 is provided with axis hole, described axis hole and the rotating shaft in mounting seat 406
409 cooperatively form revolute pair.The bottom of chuck body 410 is provided with latch hook 412, and test card 12 is provided with the locating slot of depression, institute
State latch hook 412 to match with the locating slot of depression on test card 12.
With reference to Fig. 5, automatic measuring unit 5 include fluorescence signal acquisition device 506, measure motor 503, measure driving wheel 508,
Belt 507, measurement driven pulley 505, driven carriage 504, motion guide rail 502, described motion guide rail 502, measurement driven carriage 504
It is installed on installing plate 3 with measuring motor 503, the output shaft of described measurement motor 503 is provided with a driving wheel 508,
Described measurement driving wheel 508 is connected to measure driven pulley 505 by belt 507, and described measurement driven pulley 505 is arranged on driven
On frame 504, described belt 507 is provided with fluorescence signal acquisition device 506.
With reference to Fig. 6, the fluorescence signal acquisition device 506 in automatic measuring unit 5 include packaging cartridge 511, data-interface 509,
Laser bar code identification module, signal measurement module, excitation source module, described packaging cartridge 511 upper right side is provided with data-interface
509, described data-interface 509 transmits for data, and described packaging cartridge 511 has been internally integrated laser bar code identification module, signal
Measurement module, excitation source module.
Described excitation source module includes that LED light source the 512, first collimation lens 513, exciting light optical filter 514, two-phase are divided
Look mirror the 515, first convex lens 516, described LED light source 512 is arranged on the right lower quadrant of packaging cartridge 511, the left side of LED light source 512
It is sequentially provided with the first collimation lens 513, exciting light optical filter 514, two-phase dichronic mirror 515, described two-phase dichronic mirror 515 and level
Installing in 45° angle, the lower section of described two-phase dichronic mirror 515 is provided with the first convex lens 516.LED light source 512 sends to the left and excites
Light, described exciting light is pooled directional light by the first collimation lens 513, after exciting light optical filter 514 optical electivity, single spectrum
Exciting light is projected onto two-phase dichronic mirror 515, and described two-phase dichronic mirror 515 is 45° angle with level, and exciting light is deflected 90 °, then
Planoconvex lens projects in the measured object target unit 517 of test card 12, and described measured object target unit 517 light that is excited excites last transition to move out
Transition light.
Described signal measurement module includes the first convex lens 516, two-phase dichronic mirror 515, transition light optical filter 518, second
Convex lens 519, grating 520, Transition Spectra receiver 521, described first convex lens 516, two-phase dichronic mirror 515 and excitation source
Module share, be sequentially provided with above described two-phase dichronic mirror 515 transition light optical filter the 518, second convex lens 519, grating 520,
Transition Spectra receiver 521.Transition light is collected, through the two of top through being arranged on the first convex lens 516 bottom packaging cartridge 511
Phase dichronic mirror 515, then through the transition light optical filter 518 of surface and the second convex lens 519, after being assembled by the second convex lens 519,
Through the aperture of grating 520 center, the Transition Spectra projecting packaging cartridge 511 top after removing edge diffusion interference light connects
Receive device 521, be converted to the signal of telecommunication by Transition Spectra receiver 521, test can be obtained by the intensity measuring the signal of telecommunication and block 12 institutes
Measured object target unit 517 information recorded.
Described laser bar code identification module includes laser generator the 522, second collimation lens 523, laser via 510, compiles
Number collector 525, described laser generator 522 is arranged on the right upper portion of packaging cartridge 511, below described laser generator 522
Being provided with the second collimation lens 523 and laser via 510, laser launched downwards by described laser generator 522, through the second collimation lens
Projecting through laser via 510 after 523 gatherings on the bar code colour band 524 of test card 12, fraction of laser light is inhaled by bar code colour band 524
Receiving, the numbering collector 525 that remaining transmitting laser is installed in bottom packaging cartridge 511 by reflection accepts, numbering collector
525 convert optical signal into the signal of telecommunication, obtain the bar code information of test card 12 by measuring the change of electrical signal intensity.
The test card 12 that lower section just can be hatched in the draw-in groove 201 of rotating disk 2 by fluorescence signal acquisition device 506 detects successively, swashs
Luminous measured object target unit 517 on test card 12 is carried out constituent analysis and is converted into the signal of telecommunication, fluorescence signal acquisition device simultaneously
506 recorded corresponding bar code information by laser saturating vitta code colour band 524, bar code information and measured object target unit 517 1 a pair
Should.
With reference to Fig. 7, automatic card release unit 6 includes card release push pedal 605, card release motor the 601, first synchronous pulley 602, second
Synchronous pulley 603, Timing Belt 604, described card release motor 601 is arranged on installing plate 3, the output shaft of described card release motor 601
On equipped with the first synchronous pulley 602, described first synchronous pulley 602 is connected with the second synchronous pulley 603 by Timing Belt 604,
On described Timing Belt 604, card release push pedal 605 is installed.
With reference to Fig. 8, the sample-adding unit 7 of the present embodiment includes frame 701, upright guide rail 702, slide block 705, collision detection sheet
721, photoelectric sensor 704, lifting Timing Belt 707, lifting motor 718, clutch shaft bearing 706, main shaft 712, code-disc 717, angle
Sensor 708, rotation wheel 709, rotation synchronization belt 710, electric rotating machine 711, swing arm 714, sample needle 716, described frame 701
Front is provided with upright guide rail 702, and described upright guide rail 702 is provided with the slide block 705 that can slide up and down, and described slide block 705 is left
Side is provided with Photoelectric Detection sheet 703, and the side of described frame 701 is equipped with being used for detecting the photoelectric sensor of Photoelectric Detection sheet 703
704, it is fixedly mounted on the right side of described slide block 705 on lifting Timing Belt 707, described lifting Timing Belt 707 and lifting motor 718 phase
Even, described slide block 705 center is provided with clutch shaft bearing 706, and the lower end of described main shaft 712 is arranged in clutch shaft bearing 706,
The middle part of described main shaft 712 is provided with code-disc 717 and rotates wheel 709, is provided with for detecting above or below described code-disc 717
The angular transducer 708 of code-disc 717 rotational angle, the described wheel 709 that rotates is by rotation synchronization belt 710 and electric rotating machine 711 phase
Even, the top of described main shaft 712 is fixedly linked with one end of swing arm 714, and the other end of described swing arm 714 is provided with sample needle 716.
With reference to Fig. 9, swing arm 714 being additionally provided with stirring anti-collision unit 715, described stirring anti-collision unit 715 includes compressing bullet
Spring 725, baffle plate 724, crashproof cover 723, striker 722, collision detection sheet 721, crashproof detection grating the 720, second bearing 726, stir
Mixing motor 719, stirring driving wheel 729, stirring Timing Belt 728 and stirring driven pulley 727, one end of described swing arm 714 is provided with the
Two bearings 726, are provided with sample needle 716, described sample needle 716 top and compression spring 725 one end in described second bearing 726
Being connected, described compression spring 725 other end connects has baffle plate 724, described baffle plate 724 to be arranged in crashproof cover 723, described baffle plate
724 all have through hole on crashproof cover 723, and described sample needle 716 is through through hole and the striker 722 being positioned at crashproof cover 723 top
Being connected, described striker 722 is provided with collision detection sheet 721, and described collision detection sheet 721 side is provided with crashproof detection grating
720；Described swing arm 714 is provided with stirring motor 719 in crashproof cover 723 side, and the output shaft of described stirring motor 719 passes swing arm
714 are connected with stirring driving wheel 729, and described sample needle 716 is being provided with stirring driven pulley 727 at the second bearing 726, described
Stirring driven pulley 727 is connected with stirring driving wheel 729 by stirring Timing Belt 728.When device fails or by outer masterpiece
With, when the bottom of sample needle 716 bumps against object, sample needle 716 moves upward, and makes the compression spring 725 on top compress, adds simultaneously
Striker 722 and the collision detection sheet 721 at sample pin 716 top move upward, and crashproof detection grating 720 sends signal.
The present invention is also equipped with sample and reagent unit 8, described sample and reagent unit 8 in the left side of mounting platform 1
Equipped with test tube, the sample platform of blood to be detected, described test tube proper alignment is placed in the circular hole of sample platform, certain sample
Platform can also use rack for test tube structure.
The present invention is additionally provided with display screen 11 on the installing plate 3 on right side, controls mainboard 10, printer 9, described display screen 11
It is used for showing that the result that detection is analyzed, described control mainboard 10 are used for controlling whole detector each several part co-ordination and to survey
Examination card is analyzed, stores, and described printer 9 is used for exporting printing testing result.
Embodiment described above is only the preferred embodiment of the present invention.It should be pointed out that, for the art is common
For technical staff, on the premise of without departing from technical solution of the present invention, it is also possible to make some improvement, modification, modification and replace
Changing, such as, automatically entering card unit 4 to use entering card structure or entering card mode of other, or can add rotation in entering card unit
Door or use other automatic card releases and automatic detection device to replace the structure in the present invention, these improve and modify also should
Being considered as being included in protection scope of the present invention, each part the clearest and the most definite in the present embodiment all can use prior art in addition real
Existing.
Claims (10)
1. a multichannel dry type Immunofluorescence test instrument, it is characterised in that: include mounting platform, hatch rotating disk, installing plate, from
Moving into card unit, automatic measuring unit, automatic card release unit, the right side of described mounting platform is provided with hatches rotating disk, described in incubate
Educate rotating disk and be arranged above installing plate, described installing plate is provided with and automatically enters card unit, automatic measuring unit, automatic card release list
Unit；
Described automatically entering card unit and include chart feeder frame, screw mandrel, card fixture, shaft coupling, enter card motor, described chart feeder frame is solid
Determining on a mounting board, described chart feeder frame is provided with screw mandrel, and described card fixture is arranged on screw mandrel and can backhaul along screw mandrel
Dynamic, described screw mandrel right-hand member is connected with entering card motor by shaft coupling；
Described automatic measuring unit include fluorescence signal acquisition device, measure motor, measure driving wheel, belt, measurement driven pulley, from
Dynamic support, motion guide rail, described motion guide rail, measurement driven carriage and measurement motor are respectively mounted on a mounting board, described measurement
Being provided with a driving wheel on the output shaft of motor, described measurement driving wheel is connected to measure driven pulley, described survey by belt
Amount driven pulley is arranged on driven carriage, and described belt is provided with fluorescence signal acquisition device；
Described automatic card release unit includes card release push pedal, card release motor, the first synchronous pulley, the second synchronous pulley, Timing Belt, institute
Stating card release motor to install on a mounting board, equipped with the first synchronous pulley on the output shaft of described card release motor, described first synchronizes
Belt wheel is connected by Timing Belt and the second synchronous pulley, and described Timing Belt is provided with card release push pedal.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 1, it is characterised in that: described automatically enter card
Card fixture in unit uses elastic force backstop, and described elastic force backstop includes mounting seat, feed screw nut, rotating shaft, rotation lock
Clamp tool, spinning reduction spring, described mounting seat top is provided with feed screw nut, and described feed screw nut coordinates shape with big screw lead Thread
Becoming screw pair, the lower left quarter of described mounting seat is provided with rotating shaft, equipped with spin locking fixture in described rotating shaft, and described rotation lock clamp
Tool can rotate around the shaft, and described spin locking fixture is provided with spinning reduction spring, described spinning reduction spring one end and rotation
Locking fixture is connected, and the described spinning reduction spring other end is connected with mounting seat.
A kind of automatic card feeding device of card insert type the most according to claim 2, it is characterised in that: described spin locking fixture bag
Include and stick up bar, chuck body, latch hook, axis hole, described in stick up bar and be arranged on the upper left side of chuck body, described chuck body is provided with axle
Hole, described axis hole cooperatively forms revolute pair with the rotating shaft in mounting seat, and the bottom of described chuck body is provided with latch hook, described latch hook
The locating slot of depression upper with test card matches.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 1, it is characterised in that: described automatic measurement
Fluorescence signal acquisition device in unit includes packaging cartridge, data-interface, laser bar code identification module, signal measurement module, excites
Light source module, described packaging cartridge upper right side is provided with data-interface, and described data-interface transmits for data, inside described packaging cartridge
It is integrated with laser bar code identification module, signal measurement module, excitation source module.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 1, it is characterised in that hatch rotating disk described in:
Be provided with the draw-in groove being evenly arranged, described in hatch the center of rotating disk and be provided with rotary shaft, described rotary shaft bottom is provided with electric rotating
Machine, described rotary shaft is provided with location dish, and described location dish side is provided with the angular transducer measuring the anglec of rotation.
6. according to a kind of multichannel dry type Immunofluorescence test instrument described in any one of claim 1-5, it is characterised in that: described
Multichannel dry type Immunofluorescence test instrument is provided with sample-adding unit in the left side of mounting platform.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 6, it is characterised in that: described sample-adding unit
Including frame, upright guide rail, slide block, collision detection sheet, photoelectric sensor, lifting Timing Belt, lifting motor, clutch shaft bearing, master
Axle, code-disc, angular transducer, rotation wheel, rotation synchronization belt, electric rotating machine, swing arm, sample needle, the front of described frame is provided with
Upright guide rail, described upright guide rail is provided with the slide block that can slide up and down, and is provided with Photoelectric Detection sheet on the left of described slide block, described
The side of frame, equipped with being used for detecting the photoelectric sensor of Photoelectric Detection sheet, is fixedly mounted on lifting Timing Belt on the right side of described slide block
On, described lifting Timing Belt is connected with lifting motor, and described its center position is provided with clutch shaft bearing, the lower end of described main shaft
Being arranged in clutch shaft bearing, the middle part of described main shaft is provided with code-disc and rotates wheel, is provided with use above or below described code-disc
Detecting the angular transducer of code-disc rotational angle, described rotation wheel is connected with electric rotating machine by rotation synchronization belt, described master
The top of axle is fixedly linked with one end of swing arm, and the other end of described swing arm is provided with sample needle.
Multifunctional rotary sample adding device the most according to claim 7, it is characterised in that: it is additionally provided with stirring in described swing arm anti-
Hit unit, described stirring anti-collision unit include compression spring, baffle plate, crashproof cover, striker, collision detection sheet, crashproof detection grating,
Second bearing, stirring motor, stirring driving wheel, stirring Timing Belt and stirring driven pulley, one end of described swing arm is provided with the second axle
Holding, be provided with sample needle in described second bearing, described sample needle top is connected with compression spring one end, and described compression spring is another
One end connects has baffle plate, described baffle plate to be arranged in crashproof cover, and described baffle plate and crashproof cover all have through hole, described sample needle
Being connected through through hole with the striker being positioned at crashproof cover top, described striker is provided with collision detection sheet, described collision detection sheet side
Face is provided with crashproof detection grating；Described swing arm is provided with stirring motor in crashproof cover side, and the output shaft of described stirring motor is worn
Crossing swing arm to be connected with stirring driving wheel, described sample needle is being provided with stirring driven pulley at the second bearing, and described stirring is driven
Take turns and be connected with stirring driving wheel by stirring Timing Belt.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 8, it is characterised in that: described multichannel is done
Formula Immunofluorescence test instrument is also equipped with sample and reagent unit in the left side of mounting platform.
A kind of multichannel dry type Immunofluorescence test instrument the most according to claim 9, it is characterised in that: described installation is put down
It is additionally provided with display screen on platform, controls mainboard, printer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610351351.6A CN105866452B (en) | 2016-05-24 | 2016-05-24 | A kind of multichannel dry type Immunofluorescence test instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610351351.6A CN105866452B (en) | 2016-05-24 | 2016-05-24 | A kind of multichannel dry type Immunofluorescence test instrument |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105866452A true CN105866452A (en) | 2016-08-17 |
| CN105866452B CN105866452B (en) | 2018-06-22 |
Family
ID=56635879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610351351.6A Expired - Fee Related CN105866452B (en) | 2016-05-24 | 2016-05-24 | A kind of multichannel dry type Immunofluorescence test instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105866452B (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106680494A (en) * | 2017-02-28 | 2017-05-17 | 山东麦田生物技术有限公司 | Multi-connected immunochromatography quantitative analyzer |
| CN107490703A (en) * | 2017-08-02 | 2017-12-19 | 南京岚煜生物科技有限公司 | A kind of multichannel Immunofluorescence test device |
| CN108469520A (en) * | 2018-02-09 | 2018-08-31 | 广东优尼德生物科技有限公司 | A kind of dry type immunochromatography detector and its detection method |
| CN108896777A (en) * | 2018-08-20 | 2018-11-27 | 基蛋生物科技股份有限公司 | biochemical analyzer |
| WO2019091089A1 (en) * | 2017-11-10 | 2019-05-16 | 深圳市金准生物医学工程有限公司 | Automated card withdrawal mechanism and single-channel fluorescent immunoassay instrument |
| CN111308105A (en) * | 2019-11-19 | 2020-06-19 | 长沙市鹏瑞生物科技有限公司 | Reagent card detector |
| CN114113619A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Transport mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113620A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Card feeding and discharging mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113574A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Compact integrated multichannel fluorescence immunoassay quantitative analyzer core |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050244972A1 (en) * | 2001-07-30 | 2005-11-03 | Hilson Richard O | Sample processing apparatus and methods |
| CN201035594Y (en) * | 2007-05-30 | 2008-03-12 | 罗祖明 | Driving device for movement of outdoor unattended card-dispensing machine |
| CN202057669U (en) * | 2011-05-16 | 2011-11-30 | 长春迪瑞医疗科技股份有限公司 | Probe mechanism |
| CN204462176U (en) * | 2014-12-30 | 2015-07-08 | 深圳市汇松科技发展有限公司 | A kind of crashproof sample needle |
| CN204740255U (en) * | 2015-07-27 | 2015-11-04 | 嘉兴凯实生物科技有限公司 | Detect card conveyor |
| CN204855378U (en) * | 2015-05-29 | 2015-12-09 | 广州蓝勃生物科技有限公司 | Multinomial mesh dry -type fluorescence detector of horizontal location carousel formula |
| CN205643367U (en) * | 2016-05-24 | 2016-10-12 | 湖南迪赛生物科技有限公司 | Multichannel dry -type immunofluorescence detector |
-
2016
- 2016-05-24 CN CN201610351351.6A patent/CN105866452B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050244972A1 (en) * | 2001-07-30 | 2005-11-03 | Hilson Richard O | Sample processing apparatus and methods |
| CN201035594Y (en) * | 2007-05-30 | 2008-03-12 | 罗祖明 | Driving device for movement of outdoor unattended card-dispensing machine |
| CN202057669U (en) * | 2011-05-16 | 2011-11-30 | 长春迪瑞医疗科技股份有限公司 | Probe mechanism |
| CN204462176U (en) * | 2014-12-30 | 2015-07-08 | 深圳市汇松科技发展有限公司 | A kind of crashproof sample needle |
| CN204855378U (en) * | 2015-05-29 | 2015-12-09 | 广州蓝勃生物科技有限公司 | Multinomial mesh dry -type fluorescence detector of horizontal location carousel formula |
| CN204740255U (en) * | 2015-07-27 | 2015-11-04 | 嘉兴凯实生物科技有限公司 | Detect card conveyor |
| CN205643367U (en) * | 2016-05-24 | 2016-10-12 | 湖南迪赛生物科技有限公司 | Multichannel dry -type immunofluorescence detector |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106680494A (en) * | 2017-02-28 | 2017-05-17 | 山东麦田生物技术有限公司 | Multi-connected immunochromatography quantitative analyzer |
| CN106680494B (en) * | 2017-02-28 | 2018-12-07 | 山东麦田生物技术有限公司 | Multiple immunochromatography quantitative analysis instrument |
| CN107490703A (en) * | 2017-08-02 | 2017-12-19 | 南京岚煜生物科技有限公司 | A kind of multichannel Immunofluorescence test device |
| WO2019091089A1 (en) * | 2017-11-10 | 2019-05-16 | 深圳市金准生物医学工程有限公司 | Automated card withdrawal mechanism and single-channel fluorescent immunoassay instrument |
| CN108469520A (en) * | 2018-02-09 | 2018-08-31 | 广东优尼德生物科技有限公司 | A kind of dry type immunochromatography detector and its detection method |
| CN108896777A (en) * | 2018-08-20 | 2018-11-27 | 基蛋生物科技股份有限公司 | biochemical analyzer |
| CN111308105A (en) * | 2019-11-19 | 2020-06-19 | 长沙市鹏瑞生物科技有限公司 | Reagent card detector |
| CN114113619A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Transport mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113620A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Card feeding and discharging mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113574A (en) * | 2022-01-26 | 2022-03-01 | 山东康华生物医疗科技股份有限公司 | Compact integrated multichannel fluorescence immunoassay quantitative analyzer core |
| CN114113619B (en) * | 2022-01-26 | 2022-03-29 | 山东康华生物医疗科技股份有限公司 | Transport mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113620B (en) * | 2022-01-26 | 2022-03-29 | 山东康华生物医疗科技股份有限公司 | Card feeding and discharging mechanism for fluorescence immunoassay quantitative analyzer core |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105866452B (en) | 2018-06-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105866452A (en) | Multi-channel dry type immunofluorescence detector | |
| CN105548132B (en) | Automate rotating disc type fluorescence detector | |
| CN207164074U (en) | A kind of multichannel Immunofluorescence test device | |
| CN106198480B (en) | A kind of automatic dry type fluorescence detector | |
| CA1175672A (en) | Apparatus for monitoring chemical reactions | |
| KR101868824B1 (en) | Immune reaction diagonostic automating system | |
| CN109521197B (en) | Multi-channel fluorescence immunoassay analyzer | |
| CN209673807U (en) | A kind of Portable fluorescence immunity analysis instrument | |
| CN205643367U (en) | Multichannel dry -type immunofluorescence detector | |
| CN109633186A (en) | Full-automatic fluorescence immunity analyzer | |
| CN105181591A (en) | Biochemical immune mixed analysis system and device | |
| CN110531097A (en) | A kind of colloidal gold fluorescence one immunity analysis instrument | |
| CN205138989U (en) | Biochemical immunity mixes analytical equipment | |
| CN107490703A (en) | A kind of multichannel Immunofluorescence test device | |
| CN104677827B (en) | A device and method for subtracting a visible-near-infrared diffuse reflection baseline signal based on a portable fiber optic spectrometer | |
| CN109900892A (en) | A kind of medical rotary table formula entry fluorescence immunity analyzer | |
| CN205562389U (en) | Automatic change carousel formula fluorescence detector | |
| KR20170115692A (en) | Method and apparatus with improved accuracy | |
| CN209043560U (en) | Automatic spring elasticity test equipment who changes | |
| CN215115874U (en) | Near-infrared quality detection system of different size fruits of self-adaptation | |
| CN207557110U (en) | A kind of optical de-tection means for multi-wavelength fluoroscopic examination | |
| CN201107271Y (en) | Rotary multi-channel excitation fluorescence device based on input and output optical fibers | |
| CN1448725A (en) | Method and apparatus for accomplishing ABO blood type full-automatic identification on full-automatic enzyme non-analysis meter | |
| CN214174399U (en) | Multichannel sliding type fluorescence immunoassay device | |
| CN208297531U (en) | Enzyme exempts from fluorogenic chemiluminescence composite type enzyme mark detector |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180622 Termination date: 20190524 |