CN209673807U - A kind of Portable fluorescence immunity analysis instrument - Google Patents
A kind of Portable fluorescence immunity analysis instrument Download PDFInfo
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- CN209673807U CN209673807U CN201920277692.2U CN201920277692U CN209673807U CN 209673807 U CN209673807 U CN 209673807U CN 201920277692 U CN201920277692 U CN 201920277692U CN 209673807 U CN209673807 U CN 209673807U
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Abstract
The utility model relates to a kind of Portable fluorescence immunity analysis instruments, including shell, the enclosure interior is provided with test paper slot, optical detecting module, gearshift, battery, main control module, and display screen is provided on the shell and is set to the control button of display screen side；The test paper slot is set to the bottom of shell, for placing test paper strip；The optical detecting module is set to the surface of test paper slot；Institute's displacement apparatus is set to the top of test paper slot；For the utility model by the dislocation arrangement of each components on vertical direction, so that the utility model internal structure is compact, overall volume is small, easy to carry, the reading of scan-type fluorescence data is may be implemented in optical detecting module, can repeatedly be read, accuracy of reading；The utility model does not have excessive additional function on the basis of meeting fluorescence immunoassay detection, and function is simple and practical, and production cost is low, utilizes popularization and use.
Description
Technical field
The utility model belongs to fluoroimmunoassay detection field, and in particular to a kind of Portable fluorescence immunity analysis instrument.
Background technique
Fluorescence immunity analyzer is detected and a kind of clinically widely applied instrument in medicine, mainly by sample-adding center,
Test center's two parts composition.By taking wet process immunofluorescence analysis instrument as an example, sample-adding center generally includes reaction tube disk, reagent
Three concentric discs of box disk and sample disc, test center be mainly made of liquor-transferring system, optical system, temperature control system and
Other auxiliary devices, but wet process immunofluorescence analysis instrument is mostly desktop computer, and volume is larger, and inconvenience is carried and carried.
Dry method immunofluorescence analysis instrument is made of to utilize fluorescence immune chromatography principle, the main side of fluorescence immune chromatography detection
Formula is that the fluorescence intensity of fluorescence immune chromatography test paper is detected by fluorescence immunity analyzer, so using dry method immunofluorescence point
Analyzer needs and Test paper is used together, and the major way of mainstream Experimental immunization fluorescent chromatographic detection at present is with packaged
Test strips be test basis, analysis is completed on immunofluorescence chromatographic detector, or is equipped with computer simultaneously, is connected with detector
Connect the quantitative analysis for completing sample.Immuno-chromatographic test paper strip mainly include sample pad, bonding pad, nitrocellulose filter, water absorption pad,
The parts such as plastic base are fixed with detection band and control band on nitrocellulose filter.In detection process, sample solution passes through hair
Spy's swimming on chromatography strip, while the determinand in sample and detection take the receptor generation high specific for determinand
With the immune response of high-affinity, thus immune complex is enriched with or is trapped in the detection of chromatographic material and taken, and free
Marker can then cross detection band.After the reaction was completed, detection, which takes the content of immune complex and the concentration of target checking matter, has
Certain corresponding relationship takes the content of immune complex, reference standard concentration by test strips detection after measurement immune response
Curve can quantitatively obtain the concentration of testing sample solution.
But common Portable fluorescence immunity analysis instrument is generally used currently on the market in order to protrude the completeness of function
High-performance processor, large screen touch screen and built-in miniature printer etc., thus such equipment it is general it is bulky, heavy,
Power consumption is high, inconvenient to carry and at high cost.
Utility model content
There is provided the purpose of the utility model is to overcome the deficiencies in the prior art it is a kind of it is small in size, easy to operate, function is real
Portable fluorescence immunity analysis instrument.
The technical solution of the utility model is as follows:
A kind of Portable fluorescence immunity analysis instrument, including shell, the enclosure interior are provided with test paper slot, optical detection mould
Block, gearshift, battery, main control module, display screen is provided on the shell and be set to the control of display screen side by
Key；
The test paper slot is set to the bottom of shell, for placing test paper strip；
The optical detecting module is set to the surface of test paper slot, including optical module and path channels, the light
Paths include the excitation light path channel for conducting exciting light and the receiving light path channel for conducting fluorescence emission, described
Optical module includes the light source for generating exciting light for being set to path channels one end, is set to the receiving light path channel other end
Detector for test strip fluorescence signal；
Institute's displacement apparatus is set to the top of test paper slot, for driving optical detecting module to carry out transverse reciprocating straight line fortune
It is dynamic；
The main control module is set to the side of optical detecting module, and main control module includes several functional circuits, master control mould
Block is electrically connected with optical detecting module, battery, display screen, control button, displacement module respectively.
Further, institute's displacement apparatus includes the spindle motor for being set to shell side, is horizontally set at enclosure interior
And one end be connected with spindle motor screw rod, with screw rod guide rod disposed in parallel, the spindle motor is electrically connected with main control module
It connects；The optical detecting module is set on gearshift.
Further, for the optical detecting module including further including module bodies, the optical module is set to module master
In vivo；
The excitation light path channel, receiving light path channel are set in module bodies, the receiving light path one end of the channel with
The connection of excitation light path channel；
The module bodies further include that the feed screw nut hole for being opened in module bodies side and feed screw nut hole are symmetrical arranged
Pilot hole, the feed screw nut that is set in feed screw nut hole and several optical elements for fixing optical element install
Slot；The screw rod passes through feed screw nut, is cooperated in the form of screw pair, and the guide rod passes through pilot hole.
Further, the angle between the excitation light path channel and receiving light path channel is 45 degree.
Further, the quantity of the excitation light path is 2.
Further, the optical module further includes light source optical filter, collimating mirror, collector lens group, detection optical filtering；Institute
Light source, light source optical filter, collimating mirror is stated to be set in excitation light path channel and set gradually along the conduction orientation of exciting light, it is described
Collector lens group, detection optical filtering, detector are set in receiving light path channel and set gradually along the conduction orientation of reflected light.
Further, the optical module further includes pinhole diaphragm, and the pinhole diaphragm is set to detection optical filtering and inspection
It surveys between device.
Further, the optical element mounting groove includes optical filtering slot, and the notch of the optical filtering slot is towards shell
The front end face of body, the shell relative to be provided on the corresponding position of notch change piece mouth and for close change piece mouth change piece
Door replaces detection optical filtering via piece mouth is changed.
Further, the eyeglass that the detection optical filtering includes mirror holder and is set on mirror holder, the end of the mirror holder
With the hand-held part for grip.
Further, indicator light is additionally provided on the shell, the indicator light is electrically connected with main control module, and indicator light is used
In the working condition for showing this fluorescence immunity analyzer.
Further, the control button includes upwarding key, right key, determination key and return key.
Further, the side of the shell is provided with ID card slot, and the main control module includes ID card reading circuit, institute
ID card slot is stated to be connected with ID card reading circuit.
Further, the side of the shell is provided with USB interface, and the main control module includes USB circuit, the USB
Circuit is connected with usb circuit.
Further, a sealing detection storehouse is collectively formed with test paper slot after the test paper strip insertion test paper slot.
The utility model has the advantages that
The utility model is arranged by the dislocation of each components on vertical direction, so that the utility model internal structure is tight
Gather, overall volume is small, easy to carry, the reading of scan-type fluorescence data may be implemented in optical detecting module, can repeatedly read, read
Number is accurate；The utility model does not have excessive additional function on the basis of meeting fluorescence immunoassay detection, and function is simple and practical, raw
It produces at low cost, utilizes popularization and use；It can be for the different corresponding detection optical filterings of detection project replacement, using the knot of grafting
Structure installation, detection optical filtering replacement are convenient and efficient；By the way that USB interface is arranged, convenient for the transmission of data；Using sealing detection storehouse,
Reduce interference of the ambient noise to detection optical signal.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model one embodiment.
Fig. 2 is the overlooking structure diagram of the utility model one embodiment.
Fig. 3 is the overhead sectional view of the utility model one embodiment.
Fig. 4 is the structural schematic diagram of the optical detecting module of the utility model one embodiment.
Fig. 5 is the structural schematic diagram of the detection optical filtering of the utility model one embodiment.
In figure, shell 1 changes film gate 12, upper cover 13, bottom case 14, main control module 20, indicator light 21, ID card slot 22, USB
Interface 23, control button 24, upwarding key 241, right key 242, determination key 243, return key 244, display screen 25, test paper strip 3,
Test paper slot 31, guide rod 41, screw rod 42, lead screw motor 43, optical detecting module 5, detector 51, detector mounting plate 52, needle
Hole diaphragm 53, light source mounting plate 54, light source 55, location hook 551, light source optical filter 56, collector lens group 57, collimating mirror 58, mould
Block main body 6, feed screw nut hole 61, pilot hole 62, the first excitation light path channel 63, the second excitation light path channel 64, receiving light path
Channel 65, optical filtering slot 66, detection optical filtering 7, eyeglass 71, mirror holder 72, hand-held part 73.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
Embodiment 1
As shown in Figures 1 to 4, a kind of Portable fluorescence immunity analysis instrument, including shell 1, shell 1 are internally provided with test paper
Slot 31, optical detecting module 5, gearshift, battery, main control module 20 are provided with display screen 25 on shell 1 and are set to aobvious
The control button 24 of 25 side of display screen；
Test paper slot 31 is set to the bottom of shell 1, for placing test paper strip 3；
Optical detecting module 5 is set to the surface of test paper slot 31, including optical module and path channels, path channels
Including the excitation light path channel for conducting exciting light and the receiving light path channel for conducting fluorescence emission, optical module packet
It includes and is set to the light source 55 for generating exciting light of path channels one end, is set to the receiving light path channel other end for detecting
The detector 51 of test strips fluorescence signal；
Gearshift is set to the top of test paper slot 31, for driving optical detecting module 5 to carry out transverse reciprocating straight line fortune
Dynamic, to realize the Scanning Detction of test strips in test paper strip 3, the type of gearshift includes one of the following: ball-screw is flat
Move rope, synchronous belt or chain and guide rod under structure, the translation structure of wheel and rack cooperation under motor driven, motor driven
The translation structure of cooperation；
Main control module 20 is set to the side of optical detecting module 5, and main control module 20 includes CPU main control chip and several
Functional circuit, main control module 20 are electric with optical detecting module 5, battery, display screen 25, control button 24, displacement module respectively
Connection；Functional circuit includes photoelectricity Acquisition Circuit, motor-drive circuit, display circuit etc., these functional circuits with CPU master control
Chip is connected, and these components that main control module uses all are the prior arts.
Preferably, test paper strip 3 is inserted into after test paper slot 31 and a sealing detection storehouse is collectively formed with test paper slot 31.
Preferably, gearshift use ball-screw translation structure, including be set to 1 side of shell spindle motor 43,
It is horizontally set at screw rod 42 and the guide rod 41 disposed in parallel of screw rod 42 that 1 inside of shell and one end are connected with spindle motor 43,
Spindle motor is electrically connected with main control module 20；Optical detecting module 5 is set on gearshift.
Preferably, as shown in figure 4, optical detecting module 5 is including further including module bodies 6,6 optical module of module bodies is set
It is placed in module bodies 6；Excitation light path channel, receiving light path channel 65 are set in module bodies 6, receiving light path one end of the channel
It is connected to excitation light path channel；Module bodies 6 further include the feed screw nut hole 61 for being opened in 6 side of module bodies and lead screw spiral shell
The symmetrically arranged pilot hole 62 in female hole 61, the feed screw nut being set in feed screw nut hole 61 and several for fixing optics
The optical element mounting groove of element；Screw rod 42 passes through feed screw nut, is cooperated in the form of screw pair, and guide rod 41 passes through pilot hole
62；Specifically, module bodies 6 are provided with upper surface, receiving light path channel 65 is vertically arranged and upper end opening, and detector 51 passes through
Detector mounting plate 52 is covered on upper surface and closes upper end opening.
The setting of excitation light path channel slopes, light source 55 are covered on the opening in excitation light path channel by light source mounting plate 54
And opening is sealed, it is preferred that the angle between excitation light path channel and receiving light path channel 65 is 45 degree, it is preferred that excitation
It is respectively the first excitation light path channel 63, the second excitation light path channel 64, the first excitation light path channel 63 that the quantity of optical path, which is 2,
It is symmetrical arranged with the second excitation light path channel 64.
Optionally, in order to facilitate the replacement of light source 55, in the upper end of light source mounting plate 54 setting positioning hanging hole, in module bodies
6, relative to location hook 511 is arranged on the position of positioning hanging hole, are hooked on location hook 511 positioning hanging hole to realize light source
The fixation of mounting plate upper end, reusing bolt for the lower end fixation of light source mounting plate 54 can be realized the removable of light source mounting plate 54
Unload fixation.
Preferably, optical module further includes light source optical filter 56, collimating mirror 58, collector lens group 57, detection optical filtering；Light
Source 55, light source optical filter 56, collimating mirror 58 are set in excitation light path channel and set gradually along the conduction orientation of exciting light, gather
Optical lens group 57, detection optical filtering, detector 51 are set in receiving light path channel and successively set along the conduction orientation of reflected light
It sets；Light source optical filter 56, collimating mirror 58, collector lens group 57 are the prior art.
Optionally, optical module further includes pinhole diaphragm 53, and pinhole diaphragm 53 is set to detection optical filtering and detector 51
Between and the pinhole diaphragm 53 on pin hole and test strips surface exciting light irradiation area be conjugated, only allow a test strips surface should
The fluorescence that region issues passes through.
The type of light source 55 includes at least one of the following: LED light, conduction have the optical fiber of laser exciting light；Detector 51
Type include at least one of the following: silicon photoelectric diode, silicon photodiode array or photomultiplier tube are existing skill
Art.
Preferably, indicator light 21 is additionally provided on shell 1, indicator light 21 is electrically connected with main control module 20, and indicator light 21 is used
In the working condition for showing this fluorescence immunity analyzer.
Preferably, control button 24 includes upwarding key 241, right key 242, determination key 243 and return key 244, long-pressing
Return key 244 realizes the booting and shutdown of the utility model, and the key for simplifying setting is fully able to meet detection operational requirements,.
Preferably, the side of shell 1 is provided with ID card slot 22, and main control module 20 includes ID card reading circuit, ID card insertion
Slot 22 is connected with ID card reading circuit.
Preferably, the side of shell 1 is provided with USB interface 23, and main control module 20 includes USB circuit, USB circuit and USB
23 circuit of interface is connected, it is preferred that USB interface 23 is transmitted for data and battery charging.
Embodiment 2
The present embodiment is the another embodiment based on embodiment 1, and the identical technical solution of embodiment 1 is described will
It omits, only the technical solution different from embodiment 1 is illustrated.
Different detection projects is detected by using different detection optical filterings, replacement for convenience detects optical filtering,
Optical element mounting groove includes optical filtering slot 66, and the notch of optical filtering slot 66 is towards the front end face of shell 1, and shell 1 is relatively
In be provided on the corresponding position of notch change piece mouth and for close change piece mouth change film gate 12, detection is filtered via piece mouth is changed
Light microscopic is replaced, in use, detection optical filtering is inserted in optical filtering slot 66；Preferably, detection optical filtering includes mirror holder
72 and the eyeglass 71 that is set on mirror holder 72, the end of mirror holder 72 there is the hand-held part 73 for grip.
Preferably, mirror holder 72 is connect with 66 hook of optical filtering slot
Although the utility model is described in detail with reference to the foregoing embodiments, come for those skilled in the art
Say, it is still possible to modify the technical solutions described in the foregoing embodiments, or to part of technical characteristic into
Row equivalent replacement, within the spirit and principle of the utility model, any modification, equivalent replacement, improvement and so on should all
It is included within the scope of protection of this utility model.
Claims (10)
1. a kind of Portable fluorescence immunity analysis instrument, including shell (1), it is characterised in that: the shell (1) is internally provided with examination
Paper groove (31), optical detecting module (5), gearshift, battery, main control module (20) are provided with display on the shell (1)
Screen (25) and the control button (24) for being set to display screen (25) side；
The test paper slot (31) is set to the bottom of shell (1), for placing test paper strip (3)；
The optical detecting module (5) is set to the surface of test paper slot (31), including optical module and path channels, described
Path channels include the excitation light path channel for conducting exciting light and the receiving light path channel for conducting fluorescence emission, institute
Optical module is stated to include the light source (55) for generating exciting light for being set to path channels one end, be set to receiving light path channel
The other end is used for the detector (51) of test strip fluorescence signal；
Institute's displacement apparatus is set to the top of test paper slot (31), straight for driving optical detecting module (5) to carry out transverse reciprocating
Line movement；
The main control module (20) is set to the side of optical detecting module (5), respectively with optical detecting module (5), battery,
Display screen (25), control button (24), displacement module electrical connection.
2. a kind of Portable fluorescence immunity analysis instrument according to claim 1, it is characterised in that: institute's displacement apparatus includes
It is set to the spindle motor (43) of shell (1) side, is horizontally set at shell (1) inside and one end is connected with spindle motor (43)
Screw rod (42), with screw rod (42) guide rod disposed in parallel (41), the spindle motor is electrically connected with main control module (20)；Institute
Optical detecting module (5) is stated to be set on gearshift.
3. a kind of Portable fluorescence immunity analysis instrument according to claim 2, it is characterised in that: the optical detecting module
(5) including further includes module bodies (6), and the optical module is set in module bodies (6)；
The excitation light path channel, receiving light path channel (65) are set on module bodies (6), the receiving light path one end of the channel
It is connected to excitation light path channel；
The module bodies (6) further include the feed screw nut hole (61) for being opened in module bodies (6) side and feed screw nut hole
(61) symmetrically arranged pilot hole (62), the feed screw nut that is set in feed screw nut hole (61) and several for fixing light
Learn the optical element mounting groove of element；The screw rod (42) passes through feed screw nut, is cooperated in the form of screw pair, the guide rod
(41) pilot hole (62) are passed through.
4. a kind of Portable fluorescence immunity analysis instrument according to claim 3, it is characterised in that: the excitation light path channel
Angle between receiving light path channel (65) is 45 degree.
5. a kind of Portable fluorescence immunity analysis instrument according to claim 3, it is characterised in that: the optical module also wraps
Include light source optical filter (56), collimating mirror (58), collector lens group (57), detection optical filtering；
The light source (55), light source optical filter (56), collimating mirror (58) are set to the biography in excitation light path channel and along exciting light
Direction is led to set gradually, the collector lens group (57), detection optical filtering, detector (51) be set in receiving light path channel and
Conduction orientation along reflected light is set gradually.
6. a kind of Portable fluorescence immunity analysis instrument according to claim 5, it is characterised in that: the optical module also wraps
It includes pinhole diaphragm (53), the pinhole diaphragm (53) is set between detection optical filtering and detector (51).
7. a kind of Portable fluorescence immunity analysis instrument according to claim 5, it is characterised in that: the optical element installation
Slot includes optical filtering slot (66), front end face of the notch of the optical filtering slot (66) towards shell (1), the shell (1)
Relative to be provided on the corresponding position of notch change piece mouth and for close change piece mouth change film gate (12), via changing, piece mouth is right
Detection optical filtering is replaced.
8. a kind of Portable fluorescence immunity analysis instrument according to claim 7, it is characterised in that: the detection optical filtering packet
The end of the eyeglass (71) for including mirror holder (72) and being set on mirror holder (72), the mirror holder (72) has for the hand-held of grip
Portion (73).
9. a kind of Portable fluorescence immunity analysis instrument according to claim 1, it is characterised in that: on the shell (1) also
It is provided with indicator light (21), the indicator light (21) is electrically connected with main control module (20).
10. a kind of Portable fluorescence immunity analysis instrument according to claim 1, it is characterised in that: the control button
It (24) include upwarding key (241), right key (242), determination key (243) and return key (244).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920277692.2U CN209673807U (en) | 2019-03-05 | 2019-03-05 | A kind of Portable fluorescence immunity analysis instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920277692.2U CN209673807U (en) | 2019-03-05 | 2019-03-05 | A kind of Portable fluorescence immunity analysis instrument |
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| Publication Number | Publication Date |
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| CN209673807U true CN209673807U (en) | 2019-11-22 |
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ID=68570547
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| CN201920277692.2U Active CN209673807U (en) | 2019-03-05 | 2019-03-05 | A kind of Portable fluorescence immunity analysis instrument |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111929431A (en) * | 2020-09-24 | 2020-11-13 | 南昌茂特生物科技有限公司 | Fluorescence immunoassay quantitative analyzer |
| CN112945837A (en) * | 2021-02-02 | 2021-06-11 | 云南安防科技有限公司 | Real-time monitoring device for bioaerosol |
| CN113218924A (en) * | 2021-04-25 | 2021-08-06 | 济南国益生物科技有限公司 | Chromatography detection interpretation instrument |
| CN114563582A (en) * | 2022-02-21 | 2022-05-31 | 姜籽宇 | Portable immunity analyzer and manufacturing method thereof |
| WO2023005204A1 (en) * | 2021-07-28 | 2023-02-02 | 厦门同仁心生物技术有限公司 | Portable immunofluorescence chromatography detector |
-
2019
- 2019-03-05 CN CN201920277692.2U patent/CN209673807U/en active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111929431A (en) * | 2020-09-24 | 2020-11-13 | 南昌茂特生物科技有限公司 | Fluorescence immunoassay quantitative analyzer |
| CN111929431B (en) * | 2020-09-24 | 2021-03-02 | 南昌茂特生物科技有限公司 | Fluorescence immunoassay quantitative analyzer |
| CN112945837A (en) * | 2021-02-02 | 2021-06-11 | 云南安防科技有限公司 | Real-time monitoring device for bioaerosol |
| CN113218924A (en) * | 2021-04-25 | 2021-08-06 | 济南国益生物科技有限公司 | Chromatography detection interpretation instrument |
| WO2023005204A1 (en) * | 2021-07-28 | 2023-02-02 | 厦门同仁心生物技术有限公司 | Portable immunofluorescence chromatography detector |
| CN114563582A (en) * | 2022-02-21 | 2022-05-31 | 姜籽宇 | Portable immunity analyzer and manufacturing method thereof |
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Effective date of registration: 20200330 Address after: 610000 2 / F, 3 / F, 4 / F, building 11, 733, Section 2, Furong Avenue, Yongning Town, Wenjiang District, Chengdu City, Sichuan Province Patentee after: Chengdu Northen medical laboratory Co., Ltd Address before: 450001 No. A2, No. 11 Changchun Road, Zhengzhou High-tech Industrial Development Zone, Henan Province Patentee before: ZHENGZHOU KODIA BIOTECHNOLOGY Co.,Ltd. |