CN207730771U - Hand-held fluorescence immunoassay apparatus - Google Patents

Hand-held fluorescence immunoassay apparatus Download PDF

Info

Publication number
CN207730771U
CN207730771U CN201820080415.8U CN201820080415U CN207730771U CN 207730771 U CN207730771 U CN 207730771U CN 201820080415 U CN201820080415 U CN 201820080415U CN 207730771 U CN207730771 U CN 207730771U
Authority
CN
China
Prior art keywords
module
data acquisition
fluorescence data
light source
acquisition module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201820080415.8U
Other languages
Chinese (zh)
Inventor
许行尚
杰弗瑞·陈
周丰茂
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nanjing Lanyu Biological Technology Co Ltd
Original Assignee
Nanjing Lanyu Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanjing Lanyu Biological Technology Co Ltd filed Critical Nanjing Lanyu Biological Technology Co Ltd
Priority to CN201820080415.8U priority Critical patent/CN207730771U/en
Application granted granted Critical
Publication of CN207730771U publication Critical patent/CN207730771U/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The utility model discloses a kind of hand-held fluorescence immunoassay apparatus to have shell and upper cover, shell is surrounded by accommodating cavity with upper cover, it is provided with fluorescence data acquisition module, optoelectronic scanning module and main control module in accommodating cavity, the surface of the upper cover is provided with touch screen;Fluorescence data acquisition module is placed in above optoelectronic scanning module, and main control module is connected with the fluorescence data acquisition module, optoelectronic scanning module, touch screen respectively;It further include the rest base for thering is reagent card slot to be integrated in the optoelectronic scanning module;Position of the fluorescence data acquisition module in the accommodating cavity is mobile.Fluorescence data acquisition module includes several excitation light sources, may respectively be the light source of different-waveband, realizes a tractor serves several purposes, supports the detection of multiple fluorescence bands samples, expanded the use scope of device;, reagent card fixed topology layout mobile using fluorescence data acquisition module, integral structure layout is compact, small volume, it is easy to accomplish hand-held, carrying.

Description

Hand-held fluorescence immunoassay apparatus
Technical field
The utility model belongs to fluoroimmunoassay detection field, is suitable for precisely, quickly, just more particularly, to one kind The hand-held fluorescence immunoassay apparatus of prompt, more detection wave bands.
Background technology
Fluorescence immunoassay detection technique is common a kind of detection technique in current biomedical inspection, which is to utilize quilt The characteristic that analysis substance will produce fluorescence under the excitation of special wavelength light carries out qualitative and quantitative detection to it.Due to fluorescence immunoassay Detection technique has the series of advantages such as the fast, safety and stability of high sensitivity, high specificity, detection speed, therefore is widely answered For in clinical detection, in endocrine disease detection, infectious disease detection, obstetrical and gynecological disease detection, tumor-marker analyte detection, heredity The detection fields such as section's disease detection, blood and cytology detection have broad application prospects.
The usual volume of traditional fluorescence immunity analyzer is larger, is not easy to handheld application, therefore, limits it urgent Detection field(As Laboratory, ICU, paediatrics, 120 emergency tenders, outdoor emergency speedily carry out rescue work rescue, individual soldier rescue), have inconvenient traffic, The development of economically underdeveloped area.Even if there is some products being commercialized, that there is also detection wave bands is single, complicated, can By the disadvantages such as property is poor, precision is low.
Disclose a kind of fluoroimmunoassay device in Chinese patent literature CN106248923A, including sample introduction module, Scan module, turntable module, data sampling module and reading module;The sample introduction module is set to the one of the turntable module Side, including support plate, sample introduction motor, guide groove, loading slot, chock and solenoid valve embolus, the sample introduction motor are led with described It is fixed in the support plate to slot, the loading slot is slidably connected in the guide groove, and the chock is slidably connected at institute It states in loading slot, and is drivingly connected with the sample introduction motor, the solenoid valve embolus is set in the loading slot, to lock Chock described in locking/unlocking;The scan module is set to the top of the sample introduction module, and the reading module is set to described turn Above the side of disk module;The data sampling module include sample motor, fixing bracket, lead screw, sliding block, balance guide rod and Sample pushes upturned soil, the sample motor to be fixed on the fixing bracket, one end of the lead screw and the sample motor Output end connects, and the other end is rotatably connected on the fixing bracket, and the sliding block is movably connected on the balance guide rod, One end of the sliding block is movably connected on the lead screw, and the sample promotion upturned soil is movably connected in the turntable of analytical instrument On.
Although the fluoroimmunoassay device of above-mentioned technical proposal can complete the Detection task of high-volume sample, dress It is larger to set volume, can not hold, and the detection wavelength band of instrument is limited.
Therefore, realize that instrument carries convenient for hand-held, at the same expand the detection wavelength band of instrument, improve detection sensitivity and Reliability is this field urgent problem.
Utility model content
Problem to be solved in the utility model is to provide a kind of detection of support multiband, is carried convenient for hand-held, is high-precision The hand-held fluorescence immunoassay apparatus of degree, high reliability.
In order to solve the above technical problems, the technical solution adopted in the utility model is, hand-held fluorescence immunoassay dress It sets with shell and upper cover, the shell is surrounded by accommodating cavity with the upper cover, and fluorescence is provided in the accommodating cavity Data acquisition module, optoelectronic scanning module and main control module, the surface of the upper cover are provided with touch screen;The fluorescence data is adopted Collection module is placed in above the optoelectronic scanning module, and the main control module is swept with the fluorescence data acquisition module, photoelectricity respectively Retouch module, touch screen is connected;
Wherein, the fluorescence data acquisition module includes fluorescence data collection plate, optical detector and optical path component, and The fluorescence data collection plate is placed in above the optical path component;The optical detector is placed in the centre bore of the optical path component Top is connected by tail portion pin with the fluorescence data collection plate;The fluorescence data acquisition module further includes having several Excitation light source, each excitation light source are the light source of different-waveband, several described excitation light sources are located at the optical path component In the light source hole on top;
It further include the rest base for thering is reagent card slot to be integrated in the optoelectronic scanning module;The fluorescence data acquisition module Position in the accommodating cavity is mobile.
In the above-mentioned technical solutions, fluorescence data acquisition module includes several excitation light sources, may respectively be different waves The light source of section realizes a tractor serves several purposes, supports the detection of multiple fluorescence bands samples, expanded the use scope of device;It carries out more When wave band sample detection, without device is needed to change, reduce the complexity of device operation;It is examined relative to traditional single band fluorescence immunoassay Measurement equipment, the utility model can effectively promote the utilization ratio of resource, effectively reduce equipment purchase cost;In addition, reagent card slot It is integrated in the rest base of the optoelectronic scanning module;Position of the fluorescence data acquisition module in the accommodating cavity is Mobile, reagent card fixed topology layout mobile using fluorescence data acquisition module, integral structure layout is compact, volume compared with It is small, it is easy to accomplish hand-held, carrying;Meanwhile reagent card slot is integrated in the rest base of optoelectronic scanning module, bearing is fixed In accommodating cavity, positioning accuracy when reagent card is inserted into is improved, the reliability of device detection is improved;In addition, fluorescence Data acquisition module, optoelectronic scanning module and main control module setting are in accommodating cavity so that hand-held fluorescence immunoassay fills It is compact to set Each part, it is rationally distributed, it is small, it is easy to accomplish hand-held, carrying.
Further improve is that the optical path component is provided with upper surface, and the centre bore is located at the upper surface Centre position and the bottom for leading directly to the optical path component;The light source hole is distributed on around the centre bore, the light source hole It is obliquely installed, is restrained by the four circumferential centre bores;It is additionally provided in the optical path component and is horizontally through the centre bore Track.
Optical path component had not only carried each component of light path system, but also was the sliding block of optoelectronic scanning module, with optoelectronic scanning mould Block is mutually equipped with;Centre bore is located at the centre position of the upper surface and leads directly to the bottom of the optical path component, is convenient for fluorescence data Collection plate assembly work;Light source hole is distributed on around the centre bore, and the light source hole is obliquely installed, by four it is circumferential it is described in It restrains in heart hole so that device integral layout is compact, reduces the volume of instrument, it is high that excitation light source is equipped with precision;Track is for being equipped with Optical filtering module, meets the topology layout and required precision of device, at the same be additionally provided in optical path component be horizontally through it is described The track of centre bore, this structure setting so that the optics that the fluorescent optical filter on optical filtering module can be respectively aligned to top is visited Survey device.
Further improve is that the hull outside is provided with reagent strip, and the reagent strip is inserted into institute It states in reagent card slot.
The setting of reagent strip facilitates and determinand sample is added in hull outside;Determinand sample, warp are added in reagent strip After crossing immunochromatography reaction, reagent strip is inserted into reagent card slot, clicking corresponding detection button in touch screen can carry out It operates in next step.
Further improve be, the fluorescence data acquisition module further include have the second stepper motor, optical filtering module, Pinion gear, light source optical filter and collector lens component;The light source optical filter is placed on the lower part of the excitation light source;The filter Light microscopic module is placed in the track of the optical path component, with several different fluorescent optical filters, the mobile optical filtering mould Group can make fluorescent optical filter be respectively aligned to the optical detector of top;There are rack, second step in optical filtering module tail portion Stepper motor drives the rack by pinion gear, and then optical filtering module is pushed to be moved along the track;The collector lens group Part is placed in the lower section of the optical filtering module, and below optical detector vertical optical path.
Passable in above-mentioned preferred scheme, optical filtering module is placed on the track in optical path component, is moved along track Optical filtering module can make fluorescent optical filter be respectively aligned to the optical detector of top;Furthermore it is arranged in the tail portion of optical filtering module There is rack, the second stepper motor can be with drive rack by pinion gear, and then pushes the movement of optical filtering module, realizes different-waveband Fluorescent optical filter switching;Collector lens component can converge the transmitting fluorescence of diverging, be converted into directional light, projection Onto optical detector, instrument accuracy of detection and sensitivity are promoted.
Further improve is that the optoelectronic scanning module is by the bearing, the first stepper motor, feed screw nut, institute Fluorescence data acquisition module, lead screw, the reagent card slot and guide rail is stated to constitute;First stepper motor is placed in the bearing One end;The feed screw nut is placed in a hole of the fluorescence data acquisition module;Described lead screw one end and first stepping Motor is connected, and the other end is placed in the hole of bearing front end, and the lead screw passes through feed screw nut, is coordinated in the form of screw pair;Institute The guide-track groove that guide rail passes through the fluorescence data acquisition module is stated, both ends are fixed on seat end surface;The fluorescence data acquires mould Block is connected by the guide rail and lead screw with the optoelectronic scanning module.
Take above structure, such integrated design that can not only reduce the volume of optoelectronic scanning module, while can also Improve the positioning accuracy of test card;Guide rail passes through its internal guide rail slot, and optical path component edge is led under the driving of the first stepper motor Rail axial reciprocating slides, and this structure design mode not only makes instrument integral layout compact, reduces the volume of instrument;And it can be with The assembly precision of instrument is improved, the technological process of production is reduced, improves the reliability of instrument.
Further improve be, the main control module by signal wire respectively with the fluorescence data acquisition module, light Electric scanning module, touch screen are connected;Based on the external signal driving device modules of touch screen input, detection function is realized.
Further improve is that the main control module includes CPU main control chips, photoelectricity Acquisition Circuit, motor driving Circuit, display circuit, touch screen circuitry, WIFI module, bluetooth module, USB circuit and serial port circuit;The optical detector and The excitation light source is connected with photoelectricity Acquisition Circuit respectively;Wherein, the photoelectricity Acquisition Circuit, motor-drive circuit, display electricity Road, touch screen circuitry, WIFI module, bluetooth module, USB circuit, serial port circuit are connected with the CPU main control chips.
Further improve is that the excitation light source will be swashed by LED light directly as excitation light source, or by laser It shines by fiber optic conduction to the optical path component;The optical detector is silicon photoelectric diode, silicon photoelectric diode battle array Row or photomultiplier tube.
Further improve is that the device is additionally provided with code reader;By the one-dimension code or Quick Response Code pair on test paper strip The probe of quasi- code reader, can be with the type and batch information of automatic input test paper.
Description of the drawings
It is further described below in conjunction with the accompanying drawings with the embodiment of the utility model:
Fig. 1 is the utility model hand-held fluorescence immunoassay apparatus structural schematic diagram;
Fig. 2 is the optoelectronic scanning modular structure schematic diagram in Fig. 1;
Fig. 3 is the fluorescence data acquisition module structural schematic diagram in Fig. 2;
Fig. 4 is the structural representation of optical path component in Fig. 3;
Fig. 5 is the fluorescence optical filtering module schematic diagram in Fig. 3;
Wherein:101- optoelectronic scanning modules, 102- reagent strips, 103- shells, 104- upper covers, 105- touch screens, 106- Main control module, 107- code readers, 108- house cavity, 201- bearings, the first stepper motors of 202-, 203- feed screw nut, 204- Fluorescence data acquisition module, 205- lead screws, 206- reagent card slots, 207- guide rails, 208- guide-track grooves, 301- optical path components, 302- Fluorescence data collection plate, 303- optical detectors, the second stepper motors of 304-, 305- optical filtering modules, 306- pinion gears, 307- Excitation light source, 308- light source optical filters, 309- collector lens components, 310- tracks, 311- centre bores, 312- light source holes, 313- Upper surface, 401- filter supporters, 402- fluorescent optical filters one, 403- fluorescent optical filters two, 404- fluorescent optical filters three, 405- Fluorescent optical filter four, 406- racks.
Specific implementation mode
As shown in Figure 1, being the hand-held fluorescence immunoassay apparatus of the utility model, there is shell 103 and upper cover 104, The shell 103 is surrounded by accommodating cavity 108 with the upper cover 104, and being provided with fluorescence data in the accommodating cavity 108 adopts Collection module 204, optoelectronic scanning module 101 and main control module 106, the surface of the upper cover 104 are provided with touch screen 105;It is described Fluorescence data acquisition module 204 is placed in 101 top of the optoelectronic scanning module, and the main control module 106 is distinguished by signal wire It is connected with the fluorescence data acquisition module 204, optoelectronic scanning module 101, touch screen 105;It is inputted based on touch screen 105 outer Portion's signal driving device modules realize detection function.
Wherein, as shown in figure 3, the fluorescence data acquisition module 204 includes fluorescence data collection plate 302, optics spy Device 303 and optical path component 301 are surveyed, and the fluorescence data collection plate 302 is placed in 301 top of the optical path component;The optics Detector 303 is placed in above the centre bore of the optical path component 301, passes through tail portion pin and the fluorescence data collection plate 302 It is connected;The fluorescence data acquisition module 302 further includes having several excitation light sources 307, right in the present embodiment there are four settings It answers, each excitation light source 307 is the light source of different-waveband, several described excitation light sources 307 are located at the light path group In the light source hole on 301 top of part;
It further include the rest base for thering is reagent card slot 206 to be integrated in the optoelectronic scanning module 101;The fluorescence data is adopted It is mobile to collect position of the module 101 in the accommodating cavity 108.
As shown in figure 4, the optical path component 301 is provided with upper surface 313, the centre bore 311 is located at the upper surface 313 centre position and the bottom for leading directly to the optical path component 301;The light source hole 312(One shares 4 in the present embodiment) Around the centre bore 311, the light source hole 312 is obliquely installed cloth, is restrained by the four circumferential centre bores 311;Institute It states and is additionally provided with the track 310 for being horizontally through the centre bore 311 in optical path component 301;In addition, can further be seen that from attached drawing 4 301 cross section of optical path component in the present embodiment is square, and upper surface 313 is connected by 4 inclined-planes with side, light source hole 312 are separately positioned on inclined-plane, and track 310 is arranged along the diagonal line of optical path component 301, and difference is arranged at the both ends of track 310 Jagged, that bottom of the gap close to pinion gear 306 has a scarf(An angle of optical path component 301 is cut away)If It sets the scarf and is to coordinate installation pinion gear, and realize that analytical equipment integral layout is compact, reduce the volume of device, phase It answers, a scarf is also equipped with below another notch, reduce the volume of device.
103 outside of the shell is provided with reagent strip 102, and the reagent strip 102 is inserted into the reagent card In slot 206;The fluorescence data acquisition module 204 further includes having the second stepper motor 304, optical filtering module 305, pinion gear 306, light source optical filter 308 and collector lens component 309;The light source optical filter 308 is placed under the excitation light source 307 Portion;The optical filtering module 305 is placed in the track 310 of the optical path component 301, is filtered with several different fluorescence Piece, in the present embodiment have altogether there are four, refer to Fig. 5, be fluorescent optical filter 1, fluorescent optical filter 2 403, fluorescence respectively Optical filter 3 404 and fluorescent optical filter 4 405, are arranged in the filter supporter 401 of optical filtering module 305, optical filter branch 4 optical filtering holes are provided on frame 401, fluorescent optical filter is placed in optical filtering hole;Optical filtering module 305 is placed in optical path component On track 310 in 301, optical filtering module 305 is moved along track 310, four fluorescent optical filters can be made to be respectively aligned to top The optical detector 303;305 tail portion of optical filtering module has rack 406, the second stepper motor to be driven by pinion gear 306 The dynamic rack 406, and then optical filtering module 305 is pushed to be moved along track 310;The collector lens component 309 is placed in described The lower section of optical filtering module 305, from figure 3, it can be seen that centre bore 311 is provided with a step for shelving collector lens component 309, the top of collector lens component 309 is track 310, and the part sectional drawing of optical filtering module 305, optically focused are can see in figure Lens subassembly 309 and below optical detector 303 vertical optical path.
As shown in Fig. 2, the optoelectronic scanning module 101 by the bearing, the first stepper motor 202, feed screw nut 203, The fluorescence data acquisition module 204, lead screw 205, the reagent card slot 206 and guide rail 207 are constituted;First stepper motor 202 are placed in one end of the bearing 201;The feed screw nut 203 is placed in a hole of the fluorescence data acquisition module 204; 205 one end of the lead screw is connected with first stepper motor 202, and the other end is placed in the hole of 201 front end of bearing, the lead screw 205 pass through feed screw nut 203, are coordinated in the form of screw pair;The guide rail 207 passes through the fluorescence data acquisition module 204 Guide-track groove 208, both ends are fixed on 201 end face of bearing;The fluorescence data acquisition module 204 passes through the guide rail 207 and silk Bar 205 is connected with the optoelectronic scanning module 101.
The main control module 106 include CPU main control chips, photoelectricity Acquisition Circuit, motor-drive circuit, display circuit, Touch screen circuitry, WIFI module, bluetooth module, USB circuit and serial port circuit;The optical detector and the excitation light source point It is not connected with photoelectricity Acquisition Circuit;Wherein, the photoelectricity Acquisition Circuit, motor-drive circuit, display circuit, touch screen circuitry, WIFI module, bluetooth module, USB circuit, serial port circuit are connected with the CPU main control chips, main control module use these Modular construction is to belong to existing.
The excitation light source 307 is passed exciting light by optical fiber directly as excitation light source, or by laser by LED light It is directed in the optical path component 301;The optical detector 303 is silicon photoelectric diode, silicon photodiode array or photoelectricity Letter increases pipe.
The hand-held fluorescence immunoassay apparatus of the present embodiment is additionally provided with code reader.
When specifically used:
As shown in figure 3, there are four excitation light source in fluorescence data acquisition module 204, respectively symmetrically be placed in optical path component 301 upper ends four excite in unthreaded hole, four excitation light sources 307, i.e. the first excitation light source, the second excitation light source, third exciting light Source, the corresponding wavelength of the 4th excitation light source are followed successively by A, B, C, D;Four different-wavebands are placed respectively in the lower part of excitation light source 307 Light source optical filter 308, it is corresponding as shown in figure 5, there are four fluorescent optical filter 402,403,404,405 on optical filtering module 305 Optical wavelength be followed successively by α, β, γ, δ.
After the booting of hand-held fluorescence immunoassay apparatus, initialization of the main control module 106 to completion each function module of system, Touch screen 105 is lighted into operation system interface.By on test paper strip 102 one-dimension code or Quick Response Code be directed at code reader 107 Probe, can be with the type and batch information of automatic input test paper, from figure 1 it appears that code reader 107 is located at the outer of shell On surface.Next determinand sample is added into test paper strip 102 to insert test paper strip 102 after immunochromatography reacts Enter in reagent card slot 206, clicks corresponding detection button in touch screen 105, the control system of hand-held fluorescence immunoassay apparatus System can automatically switch fluorescent optical filter according to the type of test paper, to meet the requirement of determinand fluorescent emission optical wavelength;Base simultaneously The excitation light source 307 of corresponding exciting light wave band is lighted in test paper type.
For example, as the item types a length of A of corresponding excitation light wave of determinand Test paper, fluorescent emission optical wavelength is β, So when analytical equipment detects sample, control system can start the second stepper motor 304, and pinion gear 306 is driven to rotate, driving The rack 406 of 305 end of optical filtering module makes rail linearity of the optical filtering module 305 in optical path component 301 move, will be glimmering Light optical filter 2 403 is moved to the underface of optical detector 303;Next the first excitation light source is lighted.Then start first Stepper motor 202, driving fluorescence data acquisition module 204 are moved to ELISA test strip overlying regions, the photograph of the first excitation light source It penetrates down, the fluorescence that fluorescent material can be launched in test strips, transmitting fluorescence forms parallel by the convergence of collector lens component 309 Light becomes the fluorescence that wavelength is β by the filtering of fluorescent optical filter 2 403, projects on optical detector 303, optical detection The optical signal of absorption is converted to electric signal by device 303, and main control module is passed to by the enhanced processing of fluorescence data collection plate 302 106, by analysis, the calculation processing of the CPU main control chips in main control module 106, obtain the concentration of measured matter.
The basic principles and main features and advantage of the utility model have been shown and described above.The technical staff of the industry It should be appreciated that the present utility model is not limited to the above embodiments, the above embodiments and description only describe this The principle of utility model, on the premise of not departing from the spirit and scope of the utility model, the utility model also has various change And improvement, optionally, such as excitation light source can be that the LED light of more particular excitation light source wavelength or laser pass through Fiber optic conduction obtains light source, and the quantity of excitation light source can be any number, and the optical filter number of optical filtering module can also be Any number of, the shape of optical filtering module is not limited to long strip type;Can also be circular ring type, fluorescent optical filter circumferentially, this A little changes and improvements are both fallen in claimed the scope of the utility model.The utility model requires protection scope is by appended power Sharp claim and its equivalent thereof.

Claims (9)

1. a kind of hand-held fluorescence immunoassay apparatus has shell and upper cover, the shell is surrounded by accommodating with the upper cover Cavity, which is characterized in that fluorescence data acquisition module, optoelectronic scanning module and master control mould are provided in the accommodating cavity The surface of block, the upper cover is provided with touch screen;The fluorescence data acquisition module is placed in above the optoelectronic scanning module, institute Main control module is stated respectively to be connected with the fluorescence data acquisition module, optoelectronic scanning module, touch screen;
Wherein, the fluorescence data acquisition module includes fluorescence data collection plate, optical detector and optical path component, and described Fluorescence data collection plate is placed in above the optical path component;The optical detector is placed on the centre bore of the optical path component Side, is connected by tail portion pin with the fluorescence data collection plate;The fluorescence data acquisition module further includes having several to swash Light emitting source, each excitation light source are the light source of different-waveband, several described excitation light sources are located in the optical path component In the light source hole in portion;
It further include the rest base for thering is reagent card slot to be integrated in the optoelectronic scanning module;The fluorescence data acquisition module is in institute It is mobile to state the position in accommodating cavity.
2. hand-held fluorescence immunoassay apparatus according to claim 1, which is characterized in that the optical path component is provided with Upper surface, the centre bore are located at the centre position of the upper surface and lead directly to the bottom of the optical path component;The light source hole It is distributed on around the centre bore, the light source hole is obliquely installed, and is restrained by the four circumferential centre bores;In the light path group The track for being horizontally through the centre bore is additionally provided in part.
3. hand-held fluorescence immunoassay apparatus according to claim 2, which is characterized in that the hull outside is provided with Reagent strip, and the reagent strip is inserted into the reagent card slot.
4. hand-held fluorescence immunoassay apparatus according to claim 3, which is characterized in that the fluorescence data acquires mould Block further includes having the second stepper motor, optical filtering module, pinion gear, light source optical filter and collector lens component;The light source filter Mating plate is placed on the lower part of the excitation light source;The optical filtering module is placed in the track of the optical path component, if with Dry different fluorescent optical filter, the mobile optical filtering module can be such that the optics that fluorescent optical filter is respectively aligned to top visits Survey device;There is rack in optical filtering module tail portion, and the second stepper motor drives the rack by pinion gear, and then pushes and filter Mirror module is moved along the track;The collector lens component is placed in the lower section of the optical filtering module, and is visited positioned at optics It surveys below device vertical optical path.
5. hand-held fluorescence immunoassay apparatus according to claim 4, which is characterized in that the optoelectronic scanning module by The bearing, the first stepper motor, feed screw nut, the fluorescence data acquisition module, lead screw, the reagent card slot and guide rail structure At;First stepper motor is placed in one end of the bearing;The feed screw nut is placed in the fluorescence data acquisition module In one hole;Described lead screw one end is connected with first stepper motor, and the other end is placed in the hole of bearing front end, and the lead screw is worn Feed screw nut is crossed, is coordinated in the form of screw pair;The guide rail passes through the guide-track groove of the fluorescence data acquisition module, both ends solid It is scheduled on seat end surface;The fluorescence data acquisition module is connected by the guide rail and lead screw with the optoelectronic scanning module.
6. hand-held fluorescence immunoassay apparatus according to claim 1, which is characterized in that the main control module passes through letter Number line is connected with the fluorescence data acquisition module, optoelectronic scanning module, touch screen respectively.
7. according to claim 1-6 any one of them hand-held fluorescence immunoassay apparatus, which is characterized in that the master control mould Block includes CPU main control chips, photoelectricity Acquisition Circuit, motor-drive circuit, display circuit, touch screen circuitry, WIFI module, indigo plant Tooth module, USB circuit and serial port circuit;The optical detector and the excitation light source are connected with photoelectricity Acquisition Circuit respectively; Wherein, the photoelectricity Acquisition Circuit, motor-drive circuit, display circuit, touch screen circuitry, WIFI module, bluetooth module, USB Circuit, serial port circuit are connected with the CPU main control chips.
8. hand-held fluorescence immunoassay apparatus according to claim 7, which is characterized in that the excitation light source is by LED Lamp passes through exciting light in fiber optic conduction to the optical path component directly as excitation light source, or by laser;The optics Detector is silicon photoelectric diode, silicon photodiode array or photomultiplier tube.
9. hand-held fluorescence immunoassay apparatus according to claim 8, which is characterized in that the device is additionally provided with barcode scanning Device.
CN201820080415.8U 2018-01-18 2018-01-18 Hand-held fluorescence immunoassay apparatus Active CN207730771U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201820080415.8U CN207730771U (en) 2018-01-18 2018-01-18 Hand-held fluorescence immunoassay apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201820080415.8U CN207730771U (en) 2018-01-18 2018-01-18 Hand-held fluorescence immunoassay apparatus

Publications (1)

Publication Number Publication Date
CN207730771U true CN207730771U (en) 2018-08-14

Family

ID=63083096

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201820080415.8U Active CN207730771U (en) 2018-01-18 2018-01-18 Hand-held fluorescence immunoassay apparatus

Country Status (1)

Country Link
CN (1) CN207730771U (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108181456A (en) * 2018-01-18 2018-06-19 南京岚煜生物科技有限公司 Hand-held fluorescence immunoassay apparatus
CN113686825A (en) * 2021-08-16 2021-11-23 帝鸿科技(珠海)有限公司 Hand-held fluorescence immune data acquisition instrument based on ICT

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108181456A (en) * 2018-01-18 2018-06-19 南京岚煜生物科技有限公司 Hand-held fluorescence immunoassay apparatus
CN108181456B (en) * 2018-01-18 2020-06-30 南京岚煜生物科技有限公司 Hand-held fluorescence immunoassay device
CN113686825A (en) * 2021-08-16 2021-11-23 帝鸿科技(珠海)有限公司 Hand-held fluorescence immune data acquisition instrument based on ICT

Similar Documents

Publication Publication Date Title
CN108181456A (en) Hand-held fluorescence immunoassay apparatus
EP1674852B1 (en) Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems
CN201653906U (en) Biological immunochromatography chip detector
CN107884571A (en) Portable fluorescence immunity analysis instrument and Portable fluorescence analysis method
CN102087214A (en) Fluorescent quantitative detection instrument
US7667184B2 (en) Optical information reader
CN207730771U (en) Hand-held fluorescence immunoassay apparatus
CN108181290A (en) A kind of quantitative fluorescence analysis instrument
CN109900892A (en) A kind of medical rotary table formula entry fluorescence immunity analyzer
CN202216908U (en) Fluorescent quantitative detector
CN202916200U (en) Medical fluorescent quantitation analysis meter
CN110174509A (en) A kind of spectral analysis device
CN108106994A (en) A kind of scan-type local enhances biochemical sensitive device
CN214252308U (en) Multi-channel fluorescence immunochromatography quantitative detector
CN103901009B (en) A kind of laser-induced fluorescence detection system of optical fiber scan type
CN105866075A (en) Fluorescence detection apparatus
CN206411125U (en) Portable fluorescence immunity analysis instrument
CN211471428U (en) Fluorescence scanning system for PCR instrument
CN202372445U (en) Fluorescence detection system
CN105388131A (en) Fluorescence detection instrument and system based on micro-fluidic chip
CN102087215A (en) Fluorescent quantitative detection instrument
CN207908516U (en) A kind of spectral analysis device
CN204347027U (en) A kind of optical fiber array column immunofluorescence assay device
CN206648953U (en) A kind of fluorimetric analysis device
CN1114049A (en) Multifunction Aadamard's transformation micrograph analytical instrument

Legal Events

Date Code Title Description
GR01 Patent grant
GR01 Patent grant