CN202916200U - Medical fluorescent quantitation analysis meter - Google Patents
Medical fluorescent quantitation analysis meter Download PDFInfo
- Publication number
- CN202916200U CN202916200U CN 201220598047 CN201220598047U CN202916200U CN 202916200 U CN202916200 U CN 202916200U CN 201220598047 CN201220598047 CN 201220598047 CN 201220598047 U CN201220598047 U CN 201220598047U CN 202916200 U CN202916200 U CN 202916200U
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- Prior art keywords
- fluorescence
- lens group
- test card
- detection
- analysis instrument
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- Expired - Lifetime
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- 238000004458 analytical method Methods 0.000 title claims abstract description 21
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 37
- 238000001514 detection method Methods 0.000 claims abstract description 26
- 230000003287 optical Effects 0.000 claims description 24
- 239000012491 analyte Substances 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 7
- 238000006243 chemical reaction Methods 0.000 claims description 4
- 230000005284 excitation Effects 0.000 claims description 4
- 238000007639 printing Methods 0.000 claims description 4
- 210000004369 Blood Anatomy 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 10
- 210000002700 Urine Anatomy 0.000 abstract description 9
- 239000000126 substance Substances 0.000 description 4
- 230000035945 sensitivity Effects 0.000 description 3
- 238000004737 colorimetric analysis Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000004853 microextraction Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 108010047814 Antigen-Antibody Complex Proteins 0.000 description 1
- 210000001124 Body Fluids Anatomy 0.000 description 1
- 102000025380 C-Reactive Protein Human genes 0.000 description 1
- 108010074051 C-Reactive Protein Proteins 0.000 description 1
- 102100015724 CRP Human genes 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 206010057269 Mucoepidermoid carcinoma Diseases 0.000 description 1
- 238000003556 assay method Methods 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000003260 fluorescence intensity Methods 0.000 description 1
- 238000005558 fluorometry Methods 0.000 description 1
- 238000004452 microanalysis Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000004454 trace mineral analysis Methods 0.000 description 1
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Abstract
The utility model relates to the technical field of medical detecting instruments, and provides a medical fluorescent quantitation analysis meter, which includes a casing and a fluorescent detecting system arranged inside the casing, wherein the surface of the casing is provided with an operating display screen communicated with an input end and an output end of the fluorescent detecting system respectively; a reagent detecting card inlet and a calibrating chip socket both communicated with the input end of the fluorescent detecting system are arranged on the side surface of the casing; and a groove for fixing a reagent detecting card is arranged inside the reagent detecting card inlet. As the fluorescent detecting system is used for analysis and detection for blood and urine of human bodies, the accuracy of analysis and detection is improved, concentrations of analytes in blood and urine can be analyzed quickly and quantificationally, and the use is very convenient.
Description
Technical field
The utility model relates to the medical detecting Instrument technical field, is specially a kind of medical quantitative fluorescence analysis instrument for quick, quantitative test blood and the various analyte concentrations of urine.
Background technology
The method of traditional detection blood and urine has the methods such as liquid film micro-extraction method, colorimetric analysis, wherein, liquid film micro-extraction method belongs to chemical method, because body fluid components is complicated, test substance content is low, disturbing factor is more, the sensitivity of assay method is low, and complicated operation, consumption of organic solvent are large, evaporation is many, harm operator ' s health, contaminated environment; Colorimetric analysis belongs to physical method, but it is different be used for to measure the required optical wavelength of chemical composition in the required optical wavelength of blood chemical composition and the mensuration urine, so, generally need to design two kinds of instruments and measure respectively blood and urine.
Fluoroimmunoassay (Fluoroisnmunoassay, FIA) is a kind of microanalysis method that development in recent years is got up, and is one of at present the sensitiveest trace analysis.The molecular energy of Cucumber absorb energy and launch fluorescence, according to spectrum and the fluorescence intensity of fluorescence, material is carried out qualitative or quantitative method, be called fluorometry.Fluoroimmunoassay (FIA) have high sensitivity, selectivity strong, need the advantages such as the few and method of sample size is easy, the mensuration lower limit of the method is usually than high 2～4 orders of magnitude of light splitting photometry, the application in biochemical analysis is more extensive.
The utility model content
Technical problem to be solved in the utility model is: a kind of medical quantitative fluorescence analysis instrument is provided, is used for fast, quantitative test blood and the various analyte concentrations of urine, and obtain more accurately result.
For solving the problems of the technologies described above, the utility model provides following technical scheme:
Medical quantitative fluorescence analysis instrument, comprise housing and the fluorescence detecting system that is arranged on described enclosure interior, the surface of described housing is provided with the operating display that is communicated with respectively with input end and the output terminal of described fluorescence detecting system, the housing side is provided with reagent test card entrance and the correcting chip socket that is communicated with the input end of described fluorescence detecting system, and described reagent test card entrance inside is provided with the groove for the fixating reagent test card.
Preferably, the inside of described reagent test card is provided with reagent strip, and described reagent strip is provided with detection of sign, and the upper surface of described reagent test card is provided with well and is positioned at the watch window at described detection of sign place.
Preferably, described fluorescence detecting system comprises analyzing and changing the optical assembly device of analyte in the reagent and the single-chip microcomputer that is communicated with the output terminal of described optical assembly device.
Preferably, described optical assembly device comprises led light source and the light lens group of excitation source, be used for accepting analyte fluorescence signal the fluorescent lens group and be used for the photoelectric signal converter of conversion fluorescence signal, the output terminal of described photoelectric signal converter links to each other with described single-chip microcomputer, described photoelectric signal converter and fluorescent lens group are coaxially installed on the top of described reagent test card detection of sign by one group of optical module pedestal, described led light source and light lens group are by another coaxial top that is installed in described reagent test card detection of sign of group optical module pedestal, and the center line of the center line of described photoelectric signal converter and fluorescent lens group and described led light source and light lens group intersects on the described detection of sign.
Preferably, described light lens group comprises two convex lens and a light source filter, and wherein light source filter is between described two convex lens.
Preferably, described fluorescent lens group comprises two convex lens and a fluorescence optical filtering, and wherein the fluorescence optical filtering is between described two convex lens.
Preferably, described surface of shell also is provided with the data-printing mouth that is communicated with described single-chip microcomputer.
After having adopted technique scheme, the beneficial effects of the utility model are: the utility model is owing to adopting fluorescence detecting system that blood of human body and urine are carried out analyzing and testing, not only improved and detected the accuracy of analyzing, and can be fast, various analyte concentrations in analyzing blood and the urine quantitatively, use very convenient.
Description of drawings
Fig. 1 is the signal of the utility model specific embodiment spatial structure;
Fig. 2 is the utility model reagent test card structural representation;
Fig. 3 is that the utility model quantitative fluorescence analysis instrument detects principle schematic;
Wherein, 1, operating display; 2, reagent test card entrance; 3, correcting chip socket; 4, operation push-button; 5, data-printing mouth; 6, reagent strip; 7, application of sample pad; 8, detection of sign; 9, well; 10, watch window; 11, led light source; 12, light lens group; 13, fluorescent lens group; 14, photoelectric signal converter; 15, convex lens; 16, light source filter; 17, fluorescence optical filtering.
Embodiment
Below in conjunction with accompanying drawing embodiment of the present utility model is elaborated.
A kind of medical quantitative fluorescence analysis instrument as shown in Figure 1, comprise housing and the fluorescence detecting system that is arranged on enclosure interior, the surface of housing is provided with the operating display 1 that is communicated with respectively with input end and the output terminal of fluorescence detecting system, the housing side is provided with reagent test card entrance 2 and the correcting chip socket 3 that is communicated with the input end of fluorescence detecting system, and reagent test card entrance 2 inside are provided with the groove for the fixating reagent test card.Surface of shell also is provided with operation push-button 4 and the data-printing mouth 5 of operating display 1.
Reagent test card structure as shown in Figure 2, the inside of reagent test card is provided with reagent strip 6, reagent strip 6 is provided with application of sample pad 7 and detection of sign 8, and the upper surface of reagent test card is provided with the well 9 that is positioned at application of sample pad 7 places and the watch window 10 that is positioned at detection of sign 8 places.
The quantitative fluorescence analysis instrument detects principle as shown in Figure 3, uses LED as excitation source, during detection, the detection sample behind the abundant mixing of damping fluid is joined the well of test card, and the analyte in the sample forms immune complex in chromatography process.When test card is inserted in the quantitative fluorescence analysis instrument, light source irradiation is to detection zone and the Quality Control zone of test card, excite the fluorescent material that adheres to, utilizing emitted light is collected and is converted into electric signal, the power of electric signal is strictly relevant with fluorescence molecule quantity, and the detector autoscan calculates the content of analyte in the sample to be tested.
Fluorescence detecting system comprises analyzing and changing the optical assembly device of analyte in the reagent and the single-chip microcomputer that is communicated with the output terminal of optical assembly device.
Optical assembly device comprises led light source 11 and the light lens group 12 of excitation source, be used for accepting analyte fluorescence signal fluorescent lens group 13 and be used for the photoelectric signal converter 14 of conversion fluorescence signal, the output terminal of photoelectric signal converter 14 links to each other with single-chip microcomputer, photoelectric signal converter 14 and fluorescent lens group 13 are coaxially installed on the top of reagent test card detection of sign 8 by one group of optical module pedestal, led light source 11 and light lens group 12 are by another coaxial top that is installed in reagent test card detection of sign 8 of group optical module pedestal, and the center line of the center line of photoelectric signal converter 14 and fluorescent lens group 13 and led light source 11 and light lens group 12 intersects on the detection of sign 8.
The light lens group comprises two convex lens 15 and a light source filter 16, and wherein light source filter 16 is between two convex lens 15.The fluorescent lens group comprises two convex lens 15 and a fluorescence optical filtering 17, and wherein fluorescence optical filtering 17 is between two convex lens 15.
The chromatograph test strip that the quantitative fluorescence analysis instrument is applicable to take fluorescence as label quantitatively detects such as test cards such as: omnidistance C reactive proteins in the blood (the conventional CRP of hsCRP+), have good repeatability and accuracy, the range of linearity is wide, and sensitivity is quick, accurate reliably, the quantitative detection platform of POCT of simple and effective.
This detection system only is used for vitro detection, is widely used in centralab, door/Laboratory, clinical department and other medical services point (such as the community medicine point), the MEC of medical institutions etc., also is applicable to the detection of scientific experiment chamber.
The utility model is not limited to above-mentioned concrete embodiment, and those of ordinary skill in the art is from above-mentioned design, and without performing creative labour, all conversion of having done all drop within the protection domain of the present utility model.
Claims (7)
1. medical quantitative fluorescence analysis instrument, it is characterized in that: comprise housing and the fluorescence detecting system that is arranged on described enclosure interior, the surface of described housing is provided with the operating display that is communicated with respectively with input end and the output terminal of described fluorescence detecting system, the housing side is provided with reagent test card entrance and the correcting chip socket that is communicated with the input end of described fluorescence detecting system, and described reagent test card entrance inside is provided with the groove for the fixating reagent test card.
2. medical quantitative fluorescence analysis instrument as claimed in claim 1, it is characterized in that: the inside of described reagent test card is provided with reagent strip, described reagent strip is provided with detection of sign, and the upper surface of described reagent test card is provided with well and is positioned at the watch window at described detection of sign place.
3. medical quantitative fluorescence analysis instrument as claimed in claim 2, it is characterized in that: described fluorescence detecting system comprises analyzing and changing the optical assembly device of analyte in the reagent and the single-chip microcomputer that is communicated with the output terminal of described optical assembly device.
4. medical quantitative fluorescence analysis instrument as claimed in claim 3, it is characterized in that: described optical assembly device comprises led light source and the light lens group of excitation source, be used for accepting analyte fluorescence signal the fluorescent lens group and be used for the photoelectric signal converter of conversion fluorescence signal, the output terminal of described photoelectric signal converter links to each other with described single-chip microcomputer, described photoelectric signal converter and fluorescent lens group are coaxially installed on the top of described reagent test card detection of sign by one group of optical module pedestal, described led light source and light lens group are by another coaxial top that is installed in described reagent test card detection of sign of group optical module pedestal, and the center line of the center line of described photoelectric signal converter and fluorescent lens group and described led light source and light lens group intersects on the described detection of sign.
5. medical quantitative fluorescence analysis instrument as claimed in claim 4, it is characterized in that: described light lens group comprises two convex lens and a light source filter, wherein light source filter is between described two convex lens.
6. medical quantitative fluorescence analysis instrument as claimed in claim 4, it is characterized in that: described fluorescent lens group comprises two convex lens and a fluorescence optical filtering, wherein the fluorescence optical filtering is between described two convex lens.
7. medical quantitative fluorescence analysis instrument as claimed in claim 3, it is characterized in that: described surface of shell also is provided with the data-printing mouth that is communicated with described single-chip microcomputer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220598047 CN202916200U (en) | 2012-11-13 | 2012-11-13 | Medical fluorescent quantitation analysis meter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220598047 CN202916200U (en) | 2012-11-13 | 2012-11-13 | Medical fluorescent quantitation analysis meter |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202916200U true CN202916200U (en) | 2013-05-01 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220598047 Expired - Lifetime CN202916200U (en) | 2012-11-13 | 2012-11-13 | Medical fluorescent quantitation analysis meter |
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| CN (1) | CN202916200U (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104714005A (en) * | 2013-12-13 | 2015-06-17 | 北京乐普医疗科技有限责任公司 | Quantitative analyzer |
| CN109211865A (en) * | 2018-11-17 | 2019-01-15 | 郑州亲和力科技有限公司 | A kind of quantitative fluorescence analysis instrument |
| CN109856098A (en) * | 2019-01-31 | 2019-06-07 | 陈大为 | Enhanced quantitative fluorescence analysis instrument |
| CN111239026A (en) * | 2018-11-29 | 2020-06-05 | 肖光文 | Immune cell movement speed detection system |
-
2012
- 2012-11-13 CN CN 201220598047 patent/CN202916200U/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104714005A (en) * | 2013-12-13 | 2015-06-17 | 北京乐普医疗科技有限责任公司 | Quantitative analyzer |
| CN109211865A (en) * | 2018-11-17 | 2019-01-15 | 郑州亲和力科技有限公司 | A kind of quantitative fluorescence analysis instrument |
| CN111239026A (en) * | 2018-11-29 | 2020-06-05 | 肖光文 | Immune cell movement speed detection system |
| CN109856098A (en) * | 2019-01-31 | 2019-06-07 | 陈大为 | Enhanced quantitative fluorescence analysis instrument |
| CN109856098B (en) * | 2019-01-31 | 2021-08-20 | 陈大为 | Enhanced fluorescent quantitative analyzer |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20130501 |
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| CX01 | Expiry of patent term |