CN105866452B - A kind of multichannel dry type Immunofluorescence test instrument - Google Patents
A kind of multichannel dry type Immunofluorescence test instrument Download PDFInfo
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- CN105866452B CN105866452B CN201610351351.6A CN201610351351A CN105866452B CN 105866452 B CN105866452 B CN 105866452B CN 201610351351 A CN201610351351 A CN 201610351351A CN 105866452 B CN105866452 B CN 105866452B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00207—Handling bulk quantities of analyte
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The present invention relates to a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform, it is equipped on the right side of the mounting platform and is incubated turntable, automatically into card unit, automatic measurement unit, automatic card release unit, installing plate is installed above the incubation turntable, it is equipped on the installing plate automatically into card unit, automatic measurement unit, automatic card release unit, the left side of the mounting platform is equipped with sample-adding unit, sample and reagent unit.The present invention have the advantages that speed it is fast, it is efficient, can multichannel be largely detected, accuracy it is high.
Description
Technical field
The present invention relates to detection device technical field more particularly to a kind of multichannel dry type Immunofluorescence test instrument.
Background technology
In modern medicine examines fluorometric investigation system, using the excitation measured object of special wavelength, measured object by
After the photon excitation of special wavelength, energy jump occurs, launches the photon of special wavelength, measures the intensity of transition light, so as to
The number of measured object content can be obtained.Existing fluorescence detector there are detection speed it is slow, cannot continuously automated multi-channel into
The shortcomings that row detection, and testing result is unable to automatic numbering and is corresponded to, and easily obscures, for large hospital, daily
A large amount of Detection task, needs to purchase more expensive equipment, multiple testing staff are detected, not only increase detection into
Originally it is low that labor intensity, detection efficiency, are increased, and patient also to wait until second day or third day can just take testing result,
Easy delay treatment.Invention one detection speed is fast, detection efficiency is high, can automatic numbering, automatically into card, automatic card release, automatically examine
Survey, can high-volume multichannel to be detected the fluorescence detector of analysis be the task of top priority.
Invention content
The purpose of the invention is to overcome the deficiencies of the prior art and provide a kind of novel multi-channel dry type immunofluorescence inspection
Survey instrument.
The present invention is achieved by the following technical programs：
A kind of multichannel dry type Immunofluorescence test instrument including mounting platform, is incubated turntable, installing plate, automatically into card list
Member, automatic measurement unit, automatic card release unit, are equipped with incubation turntable on the right side of the mounting platform, on the incubation turntable
Side is equipped with installing plate, is equipped on the installing plate automatically into card unit, automatic measurement unit, automatic card release unit.
It is described automatically into card unit include chart feeder frame, screw, card fixture, shaft coupling, into card motor, the chart feeder
Frame is fixed on a mounting board, and the chart feeder frame is equipped with screw, and the card fixture is on screw and can come along screw
Backhaul dynamic, the screw right end is connected by shaft coupling with into card motor.
The automatic measurement unit is driven including fluorescence signal acquisition device, measurement motor, measurement driving wheel, belt, measurement
Wheel, driven carriage, motion guide rail, the motion guide rail, measurement driven carriage and measurement motor are respectively mounted on a mounting board, described
Driving wheel there are one installations on the output shaft of measurement motor, the measurement driving wheel to be connected to measurement driven wheel, institute by belt
It states and measures driven wheel on driven carriage, fluorescence signal acquisition device is provided on the belt.
The automatic card release unit includes card release push plate, card release motor, the first synchronous pulley, the second synchronous pulley, synchronization
Band, card release motor installation on a mounting board, equipped with the first synchronous pulley on the output shaft of the card release motor, described first
Synchronous pulley is connected by synchronous belt with the second synchronous pulley, and card release push plate is equipped on the synchronous belt.
Further, it is described automatically into the card fixture in card unit using elastic force backstop, the elastic force backstop packet
Mounting base, feed screw nut, shaft, spin locking fixture, spinning reduction spring are included, the mounting base top is equipped with feed screw nut,
The feed screw nut and big screw lead Thread cooperatively form screw pair, and the lower left quarter of the mounting base is equipped with shaft, in the shaft
Equipped with spin locking fixture, the spin locking fixture can rotate around the shaft, and the spin locking fixture is equipped with spinning reduction
Spring, the spinning reduction spring one end are connected with spin locking fixture, the spinning reduction spring other end and mounting base phase
Even.
Further, the spin locking fixture includes sticking up bar, chuck body, latch hook, axis hole, and the bar that sticks up is mounted on folder
Having the upper left side of ontology, the chuck body is equipped with axis hole, and the axis hole cooperatively forms revolute pair with the shaft in mounting base,
The lower part of the chuck body is equipped with latch hook, and the locating slot being recessed on the latch hook and test card matches.
Further, the fluorescence signal acquisition device in the automatic measurement unit includes packaging cartridge, data-interface, laser strip
Code identification module, signal measurement module, excitation light source module, the packaging cartridge upper right side are equipped with data-interface, and the data connect
Mouth has been internally integrated laser bar code identification module, signal measurement module, excitation light source mould for data transmission, the packaging cartridge
Block.
Further, the turntable that is incubated is equipped with the card slot being evenly arranged, and the center for being incubated turntable is equipped with rotation
Axis, the rotary shaft lower part are equipped with electric rotating machine, and the rotary shaft is equipped with positioning disk, and the positioning disk side, which is equipped with, to be measured
The angular transducer of rotation angle.
Further, the multichannel dry type Immunofluorescence test instrument is equipped with sample-adding unit in the left side of mounting platform.
Further, the sample-adding unit includes rack, upright guide rail, sliding block, collision detection piece, photoelectric sensor, liter
Synchronous belt, lifting motor, clutch shaft bearing, main shaft, code-disc, angular transducer, rotating wheel, rotation synchronization belt, electric rotating machine, pendulum drop
Arm, sample needle, the front of the rack are equipped with upright guide rail, are equipped with the sliding block that can slide up and down on the upright guide rail, institute
It states and Photoelectric Detection piece is equipped on the left of sliding block, the side of the rack is equipped with the photoelectric sensor for being used for detecting Photoelectric Detection piece, institute
It states and is fixedly mounted on the right side of sliding block on lifting synchronous belt, the lifting synchronous belt is connected with lifting motor, the center position
It puts and clutch shaft bearing is installed, the lower end of the main shaft is mounted in clutch shaft bearing, and code-disc and rotation are equipped in the middle part of the main shaft
Runner, the angular transducer for being used for detecting code-disc rotational angle is equipped with above or below the code-disc, and the rotating wheel passes through
Rotation synchronization belt is connected with electric rotating machine, and the top of the main shaft and one end of swing arm are fixedly linked, the other end of the swing arm
Equipped with sample needle.
Further, stirring anti-collision unit is additionally provided in the swing arm, the stirring anti-collision unit includes compressed spring, gear
Plate, anticollision cover, striker, collision detection piece, anticollision detection grating, second bearing, stirring motor, stirring driving wheel, stirring synchronize
Band and stirring driven wheel, one end of the swing arm are equipped with second bearing, sample needle, the sample-adding are equipped in the second bearing
Needle top is connected with compressed spring one end, and the compressed spring other end is connected with baffle, and the baffle is mounted in anticollision cover,
Through-hole is provided on the baffle and anticollision cover, the sample needle passes through through-hole to be connected with the striker positioned at anticollision cover top, institute
Striker is stated equipped with collision detection piece, the collision detection piece side is equipped with anticollision detection grating；The swing arm is in anticollision cover
Side is equipped with stirring motor, and the output shaft of the stirring motor passes through swing arm to be connected with stirring driving wheel, the sample needle by
Stirring driven wheel is equipped at nearly second bearing, the stirring driven wheel is connected by stirring synchronous belt with stirring driving wheel.
Further, the multichannel dry type Immunofluorescence test instrument is also equipped with sample and examination on the left of mounting platform
Agent unit.
Further, display screen, control mainboard, printer are additionally provided on the mounting platform.
The technique effect of the present invention is as follows：
The present invention is incubated turntable, swing arm Anti-collision sample-adding unit, automatically into card unit, automatic using rotary automatic positioning
Measuring unit, automatic card release unit, can be automatically performed from sampling, into card, detect, encode, analyze, store, to move back card etc. a series of
Action has that simple in structure, volume compact, speed is fast, efficiency, it can be achieved that the automatic continuous detection and analysis of high-volume test card
It is high, can multichannel largely detects, accuracy is high, uses manpower and material resources sparingly, shortens the advantages of detection time, solve existing detector
Detection speed is slow, the degree of automation is low, easily obscure, detection time is long, testing result comes out the problems such as slow, personnel depaly is more.
The present invention also have the function of sampling probe anticollision, liquid level accurately control, automatic alarm etc..
Description of the drawings
Fig. 1 is the structure diagram of the embodiment of the present invention 1.
Fig. 2 is the structure diagram of the embodiment of the present invention 2.
Fig. 3 is automatically into the structure diagram of card unit.
Fig. 4 is the structure diagram of elastic force backstop.
Fig. 5 is the structure diagram of automatic measurement unit.
Fig. 6 is the structure diagram of fluorescence signal acquisition device.
Fig. 7 is the structure diagram of automatic card release unit.
Fig. 8 is the structure diagram for being loaded unit.
Fig. 9 is the structure diagram for stirring anti-collision unit.
In attached drawing, 1-mounting platform, 2-incubation turntable, 201-card slot, 202-rotary shaft, 3-installing plate, 4-
Automatically into card unit, 401-chart feeder frame, 402-screw, 403-card fixture, 404-shaft coupling, 405-into card
Motor, 406-mounting base, 407-feed screw nut, 408-stick up bar, 409-shaft, 410-chuck body, 411-rotation
Turn resetting spring, 412-latch hook, 5-automatic measurement unit, 501-mounting base, 502-motion guide rail, 503-measurement electricity
Machine, 504-driven carriage, 505-driven wheel, 506-fluorescence signal acquisition device, 507-belt, 508-driving wheel, 509-
Data-interface, 510-laser via, 511-packaging cartridge, 512-LED light source, the 513-the first collimation lens, 514-exciting light
Optical filter, 515-two-phase dichronic mirror, the 516-the first convex lens, 517-measured object target member, 518-transition light optical filter,
519-the second convex lens, 520-grating, 521-Transition Spectra receiver, 522-laser generator, the 523-the second collimation are saturating
Mirror, 524-bar code colour band, 525-number collector, 6-automatic card release unit, 601-card release motor, 602-the first synchronizes
Belt wheel, the 603-the second synchronous pulley, 604-synchronous belt, 605-card release push plate, 7-sample-adding unit, 701-rack,
702-upright guide rail, 703-Photoelectric Detection piece, 704-photoelectric sensor, 705-sliding block, 706-clutch shaft bearing,
707-lifting synchronous belt, 708-angular transducer, 709-rotating wheel, 710-rotation synchronization belt, 711-electric rotating
Machine, 712-main shaft, 713-detecting liquid level module, 714-swing arm, 715-stirring anti-collision unit, 716-sample needle,
717-code-disc, 718-lifting motor, 719-stirring motor, 720-anticollision detection grating, 721-collision detection piece,
722-striker, 723-anticollision cover, 724-baffle, 725-compressed spring, 726-second bearing, 727-stirring from
Driving wheel, 728-stirring synchronous belt, 729-stirring driving wheel, 8-sample and reagent unit, 9-printer, 10-control
Mainboard, 11-display screen, 12-test card.
Specific embodiment
Below in conjunction with attached drawing, the present invention is described in further detail.
Embodiment 1
With reference to Fig. 1, a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform 1, be incubated turntable 2, installing plate 3,
Automatically into card unit 4, automatic measurement unit 5, automatic card release unit 6, the mounting platform 1, which is equipped with, is incubated turntable 2, described to incubate
It educates turntable 2 and is equipped with the card slot 201 that is evenly arranged, the card slot 201 is used for installing test card 12, and card slot 201 is along being incubated turntable 2
Radial direction be evenly arranged.The center for being incubated turntable 2 is equipped with rotary shaft 202, and the rotary shaft 202 is mounted on mounting platform 1
On, the incubation turntable 2 can be rotated along rotary shaft 202.It is incubated 2 top of turntable and installing plate 3 is installed, pacify on the installing plate 3
Equipped with automatically into card unit 4, automatic measurement unit 5, automatic card release unit 6.
It is described to include chart feeder frame 401, screw 402, card fixture 403, shaft coupling into card unit 4 automatically with reference to Fig. 3
404th, into card motor 405, the chart feeder frame 401 is fixed on installing plate 3, and the chart feeder frame 401 is equipped with screw 402,
The card fixture 403 is mounted on screw 402 and can be moved back and forth along screw 402, and 402 right end of screw passes through shaft coupling
404 are connected with into card motor 405.
With reference to Fig. 5, the automatic measurement unit 5 includes fluorescence signal acquisition device 506, measurement motor 503, measures driving wheel
508th, belt 507, measurement driven wheel 505, driven carriage 504, motion guide rail 502, the motion guide rail 502 measure driven branch
Frame 504 and measurement motor 503 are installed on installing plate 3, and there are one driving wheels for installation on the output shaft of the measurement motor 503
508, it is described measurement driving wheel 508 by belt 507 be connected to measure driven wheel 505, it is described measurement driven wheel 505 be mounted on from
On dynamic stent 504, fluorescence signal acquisition device 506 is provided on the belt 507.
With reference to Fig. 6, the automatic card release unit 6 include card release push plate 605, card release motor 601, the first synchronous pulley 602,
Second synchronous pulley 603, synchronous belt 604, the card release motor 601 be mounted on installing plate 3 on, the card release motor 601 it is defeated
Pass through synchronous belt 604 and 603 phase of the second synchronous pulley equipped with the first synchronous pulley 602, first synchronous pulley 602 on shaft
Even, card release push plate 605 is installed on the synchronous belt 604.When needing card release, card release motor 601 starts, and drives synchronous belt
604 movements, so as to drive card slot 201 of the card release push plate 605 on synchronous belt 604 by test card 12 from incubation turntable 2
Middle release.
Embodiment 2
With reference to Fig. 2, a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform 1, be incubated turntable 2, installing plate 3,
Automatically into card unit 4, automatic measurement unit 5, automatic card release unit 6.The left side of the mounting platform 1 is equipped with sample-adding unit 7, institute
The right side for stating mounting platform 1 is equipped with incubation turntable 2, and the turntable 2 that is incubated is equipped with the card slot 201 being evenly arranged, described to incubate
The center for educating turntable 2 is equipped with rotary shaft 202, and 202 lower part of rotary shaft is equipped with driving motor, is set in the rotary shaft 202
There is positioning disk, the positioning disk side is equipped with the sensor for measuring rotation angle.It is incubated 2 top of turntable and installing plate 3, institute is installed
It states and is equipped on installing plate 3 automatically into card unit 4, automatic measurement unit 5, automatic card release unit 6.
With reference to Fig. 3, automatically into card unit 4 include chart feeder frame 401, screw 402, card fixture 403, shaft coupling 404, into
Card motor 405, the chart feeder frame 401 are fixed on installing plate 3, and the chart feeder frame 401 is equipped with screw 402, the card
Plate clamp 403 is mounted on screw 402 and can be moved back and forth along screw 402,402 right end of screw by shaft coupling 404 and
It is connected into card motor 405.
With reference to Fig. 4, elastic force backstop is used into the card fixture 403 in card unit 4 automatically, the elastic force backstop includes
Mounting base 406, feed screw nut 407, shaft 409, spin locking fixture, spinning reduction spring 411,406 top of mounting base
Equipped with feed screw nut 407, the feed screw nut 407 cooperatively forms 402 pair of screw, the mounting base 406 with big screw lead Thread 402
Lower left quarter be equipped with shaft 409, equipped with spin locking fixture in the shaft 409, the spin locking fixture can around the shaft 409
Rotation, the spin locking fixture are equipped with spinning reduction spring 411, described 411 one end of spinning reduction spring and spin locking
Fixture is connected, and 411 other end of spinning reduction spring is connected with mounting base 406.
The spin locking fixture includes sticking up bar 408, chuck body 410, latch hook 412, axis hole, and the bar 408 that sticks up is installed
On the upper left side of chuck body 410, the chuck body 410 is equipped with axis hole, the axis hole and the shaft in mounting base 406
409 cooperatively form revolute pair.The lower part of chuck body 410 is equipped with latch hook 412, and test card 12 is equipped with the locating slot of recess, institute
The locating slot being recessed in latch hook 412 and test card 12 is stated to match.
With reference to Fig. 5, automatic measurement unit 5 include fluorescence signal acquisition device 506, measurement motor 503, measure driving wheel 508,
Belt 507 measures driven wheel 505, driven carriage 504, motion guide rail 502, and the motion guide rail 502 measures driven carriage 504
It is installed on installing plate 3 with measurement motor 503, driving wheel 508 there are one installations on the output shaft of the measurement motor 503,
The measurement driving wheel 508 is connected to by belt 507 measures driven wheel 505, and the measurement driven wheel 505 is mounted on driven branch
On frame 504, fluorescence signal acquisition device 506 is provided on the belt 507.
With reference to Fig. 6, the fluorescence signal acquisition device 506 in automatic measurement unit 5 include packaging cartridge 511, data-interface 509,
Laser bar code identification module, signal measurement module, excitation light source module, 511 upper right side of packaging cartridge are equipped with data-interface
509, the data-interface 509 is used for data transmission, and the packaging cartridge 511 has been internally integrated laser bar code identification module, signal
Measurement module, excitation light source module.
The excitation light source module includes LED light source 512, the first collimation lens 513, exciting light optical filter 514, two-phase point
Look mirror 515, the first convex lens 516, the LED light source 512 are mounted on the right lower quadrant of packaging cartridge 511, the left side of LED light source 512
It is equipped with the first collimation lens 513, exciting light optical filter 514, two-phase dichronic mirror 515, the two-phase dichronic mirror 515 and level successively
It is installed in 45° angle, the lower section of the two-phase dichronic mirror 515 is equipped with the first convex lens 516.LED light source 512 sends out excitation to the left
Light, the exciting light pool directional light by the first collimation lens 513, after 514 optical electivity of exciting light optical filter, single spectrum
Exciting light is projected onto two-phase dichronic mirror 515, and for the two-phase dichronic mirror 515 with horizontal in 45° angle, exciting light is deflected 90 °, then
Planoconvex lens are projected in the measured object target member 517 of test card 12, the measured object target member 517 be excited light excitation last transition move out
Transition light.
The signal measurement module includes the first convex lens 516, two-phase dichronic mirror 515, transition light optical filter 518, second
Convex lens 519, grating 520, Transition Spectra receiver 521, first convex lens 516, two-phase dichronic mirror 515 and excitation light source
Module shares, 515 top of the two-phase dichronic mirror be equipped with successively transition light optical filter 518, the second convex lens 519, grating 520,
Transition Spectra receiver 521.The first convex lens 516 that transition light passes through mounted on 511 bottom of packaging cartridge is collected, across the two of top
Phase dichronic mirror 515, then transition light optical filter 518 and the second convex lens 519 through surface, after being assembled by the second convex lens 519,
Across the aperture of 520 center of grating, the Transition Spectra that 511 top of packaging cartridge is projected after removal edge diffusion interference light connects
Device 521 is received, electric signal is converted to by Transition Spectra receiver 521,12 institute of test card can obtain by the intensity for measuring electric signal
First 517 information of the measured object target of record.
The laser bar code identification module includes laser generator 522, the second collimation lens 523, laser via 510, compiles
Number collector 525, the laser generator 522 are mounted on the right upper portion of packaging cartridge 511,522 lower section of laser generator
Equipped with the second collimation lens 523 and laser via 510, the laser generator 522 emits downwards laser, through the second collimation lens
It is projected on the bar code colour band 524 of test card 12 across laser via 510 after 523 aggregations, fraction of laser light is inhaled by bar code colour band 524
It receives, the number collector 525 that remaining transmitting laser is installed in 511 bottom of packaging cartridge by reflection receives, number collector
525 convert optical signal into electric signal, and the bar code information of test card 12 is obtained by the change for measuring electrical signal intensity.
The test card 12 that fluorescence signal acquisition device 506 can be incubated lower section in the card slot 201 of turntable 2 detects successively, swashs
It shines and constituent analysis is carried out to the measured object target member 517 in test card 12 and is converted into electric signal, while fluorescence signal acquisition device
506 are recorded corresponding bar code information by the saturating vitta code colour band 524 of laser, and bar code information and measured object target member 517 1 are a pair of
It should.
With reference to Fig. 7, automatic card release unit 6 includes card release push plate 605, card release motor 601, the first synchronous pulley 602, second
Synchronous pulley 603, synchronous belt 604, the card release motor 601 are mounted on installing plate 3, the output shaft of the card release motor 601
It is upper that equipped with the first synchronous pulley 602, first synchronous pulley 602 is connected by synchronous belt 604 with the second synchronous pulley 603,
Card release push plate 605 is installed on the synchronous belt 604.
With reference to Fig. 8, the sample-adding unit 7 of the present embodiment includes rack 701, upright guide rail 702, sliding block 705, collision detection piece
721st, photoelectric sensor 704, lifting synchronous belt 707, lifting motor 718, clutch shaft bearing 706, main shaft 712, code-disc 717, angle
Sensor 708, rotating wheel 709, rotation synchronization belt 710, electric rotating machine 711, swing arm 714, sample needle 716, the rack 701
Front is equipped with upright guide rail 702, and the sliding block 705 that can slide up and down is equipped on the upright guide rail 702, and the sliding block 705 is left
Side is equipped with Photoelectric Detection piece 703, and the side of the rack 701 is equipped with the photoelectric sensor for being used for detecting Photoelectric Detection piece 703
704,705 right side of sliding block is fixedly mounted on lifting synchronous belt 707, the lifting synchronous belt 707 and 718 phase of lifting motor
Even, 705 center of sliding block is equipped with clutch shaft bearing 706, and the lower end of the main shaft 712 is mounted in clutch shaft bearing 706,
The middle part of the main shaft 712 is equipped with code-disc 717 and rotating wheel 709, is equipped with above or below the code-disc 717 and is used for detecting
The angular transducer 708 of 717 rotational angle of code-disc, the rotating wheel 709 pass through rotation synchronization belt 710 and 711 phase of electric rotating machine
Even, the top and one end of swing arm 714 of the main shaft 712 are fixedly linked, and the other end of the swing arm 714 is equipped with sample needle 716.
With reference to Fig. 9, stirring anti-collision unit 715 is additionally provided in swing arm 714, the stirring anti-collision unit 715 includes compression bullet
Spring 725, anticollision cover 723, striker 722, collision detection piece 721, anticollision detection grating 720, second bearing 726, stirs baffle 724
Mix motor 719, stirring driving wheel 729, stirring synchronous belt 728 and stirring driven wheel 727, one end of the swing arm 714 is equipped with the
Two bearings 726 are equipped with sample needle 716,716 top of sample needle and 725 one end of compressed spring in the second bearing 726
It is connected, 725 other end of compressed spring is connected with baffle 724, and the baffle 724 is mounted in anticollision cover 723, the baffle
724 with being provided with through-hole on anticollision cover 723, the sample needle 716 passes through through-hole and the striker 722 positioned at 723 top of anticollision cover
It is connected, the striker 722 is equipped with collision detection piece 721, and 721 side of collision detection piece is equipped with anticollision detection grating
720；The swing arm 714 is equipped with stirring motor 719 in 723 side of anticollision cover, and the output shaft of the stirring motor 719 passes through swing arm
714 are connected with stirring driving wheel 729, and the sample needle 716 is being equipped with stirring driven wheel 727 at second bearing 726, described
Stirring driven wheel 727 is connected by stirring synchronous belt 728 with stirring driving wheel 729.When device fails or by outer masterpiece
With when the lower part of sample needle 716 bumps against object, sample needle 716 moves upwards, and compresses the compressed spring 725 on top, adds simultaneously
The striker 722 and collision detection piece 721 at 716 top of sample needle move upwards, and anticollision detection grating 720 sends out signal.
The present invention is also equipped with sample and reagent unit 8 in the left side of mounting platform 1, and the sample and reagent unit 8 are
Test tube, sample platform equipped with blood to be detected, the test tube proper alignment are placed in the circular hole of sample platform, certain sample
Platform can also use rack for test tube structure.
The present invention is additionally provided with display screen 11, control mainboard 10, printer 9, the display screen 11 on the installing plate 3 on right side
For showing detection and analysis as a result, the control mainboard 10 is used for controlling whole detector each section co-ordination and to surveying
Examination card is analyzed, is stored, and the printer 9 is used for exporting printing testing result.
Embodiment described above is only the preferred embodiment of the present invention.It should be pointed out that for the common of the art
For technical staff, under the premise of technical solution of the present invention is not departed from, several improvement, modification, modification can also be made and replaced
It changes, for example, others may be used into card structure or into card mode or into adding in rotation in card unit into card unit 4 automatically
Door replaces the structure in the present invention using other automatic card releases and automatic detection device, these improvement and modification also should
It is considered as and is included in protection scope of the present invention, the available prior art of each component part being not known in the present embodiment is subject to reality
It is existing.
Claims (5)
1. a kind of multichannel dry type Immunofluorescence test instrument, including mounting platform, be incubated turntable, installing plate, automatically into card unit,
Automatic measurement unit, automatic card release unit are equipped with incubation turntable on the right side of the mounting platform, pacify above the incubation turntable
Equipped with installing plate, it is equipped on the installing plate automatically into card unit, automatic measurement unit, automatic card release unit；It is described automatic
Into card unit include chart feeder frame, screw, card fixture, shaft coupling, into card motor, the chart feeder frame is fixed on installing plate
On, the chart feeder frame is equipped with screw, and the card fixture is mounted on screw and can be moved back and forth along screw, the screw
Right end is connected by shaft coupling with into card motor；The automatic measurement unit includes fluorescence signal acquisition device, measurement motor, measurement
Driving wheel, belt measure driven wheel, driven carriage, motion guide rail, and the motion guide rail measures driven carriage and measurement motor
It is respectively mounted on a mounting board, driving wheel there are one installations on the output shaft of the measurement motor, the measurement driving wheel to pass through skin
Band connection is mounted on driven carriage to driven wheel, the measurement driven wheel is measured, is provided with fluorescence signal on the belt and adopts
Storage；The automatic card release unit includes card release push plate, card release motor, the first synchronous pulley, the second synchronous pulley, synchronous belt,
The card release motor installation is on a mounting board, same equipped with the first synchronous pulley, described first on the output shaft of the card release motor
Step belt wheel is connected by synchronous belt with the second synchronous pulley, and card release push plate is equipped on the synchronous belt, it is characterised in that：
Described to use elastic force backstop into the card fixture in card unit automatically, the elastic force backstop includes mounting base, screw
Nut, shaft, spin locking fixture, spinning reduction spring, the mounting base top be equipped with feed screw nut, the feed screw nut with
Big screw lead Thread cooperatively forms screw pair, and the lower left quarter of the mounting base is equipped with shaft, rotation lock clamp is housed in the shaft
Tool, the spin locking fixture can rotate around the shaft, and the spin locking fixture is equipped with spinning reduction spring, and the rotation is multiple
Position spring one end is connected with spin locking fixture, and the spinning reduction spring other end is connected with mounting base, the spin locking
Fixture includes sticking up bar, chuck body, latch hook, axis hole, and the bar that sticks up is on the upper left side of chuck body, the chuck body
Equipped with axis hole, the axis hole cooperatively forms revolute pair with the shaft in mounting base, and the lower part of the chuck body is equipped with latch hook, institute
The locating slot being recessed in latch hook and test card is stated to match.
2. a kind of multichannel dry type Immunofluorescence test instrument according to claim 1, it is characterised in that：The automatic measurement
Fluorescence signal acquisition device in unit includes packaging cartridge, data-interface, laser bar code identification module, signal measurement module, excitation
Light source module, the packaging cartridge upper right side are equipped with data-interface, and the data-interface is used for data transmission, inside the packaging cartridge
It is integrated with laser bar code identification module, signal measurement module, excitation light source module；
The excitation light source module includes LED light source, the first collimation lens, exciting light optical filter, two-phase dichronic mirror, the first convex lens
Mirror, the LED light source are mounted on the right lower quadrant of packaging cartridge, and the left side of LED light source is equipped with the first collimation lens successively, exciting light is filtered
Mating plate, two-phase dichronic mirror, the two-phase dichronic mirror are installed with horizontal in 45° angle, and the lower section of the two-phase dichronic mirror is equipped with first
Convex lens, LED light source send out exciting light to the left, and the exciting light pools directional light by the first collimation lens, filtered through exciting light
After mating plate optical electivity, single spectrum exciting light is projected onto two-phase dichronic mirror, and the two-phase dichronic mirror, in 45° angle, swashs with horizontal
It shines deflected 90 °, then planoconvex lens are projected in the measured object target member of test card, the measured object target member is excited light excitation
Last transition is moved out transition light；
The signal measurement module includes the first convex lens, two-phase dichronic mirror, transition light optical filter, the second convex lens, grating, jump
Move spectral receiver, first convex lens, two-phase dichronic mirror and excitation light source module share, above the two-phase dichronic mirror according to
Secondary to be equipped with transition light optical filter, the second convex lens, grating, Transition Spectra receiver, transition light is passed through mounted on packaging cartridge bottom
First convex lens is collected, across the two-phase dichronic mirror of top, then transition light optical filter and the second convex lens through surface, by the
After the aggregation of two convex lenses, across the aperture of raster center position, projected at the top of packaging cartridge after removal edge diffusion interference light
Transition Spectra receiver, electric signal is converted to by Transition Spectra receiver, and test card is can obtain by the intensity for measuring electric signal
Recorded measured object target metamessage；
The laser bar code identification module includes laser generator, the second collimation lens, laser via, number collector, described
Laser generator is mounted on the right upper portion of packaging cartridge, is equipped with the second collimation lens below the laser generator and laser leads to
Road, the laser generator emit downwards laser, and test card is projected across laser via after the aggregation of the second collimation lens
On bar code colour band, fraction of laser light is absorbed by bar code colour band, and remaining transmitting laser is installed in packaging cartridge bottom by reflection
Number collector receives, and number collector converts optical signal into electric signal, surveyed by the change for measuring electrical signal intensity
Try the bar code information of card.
3. according to a kind of multichannel dry type Immunofluorescence test instrument of claim 1-2 any one of them, it is characterised in that：It is described
Multichannel dry type Immunofluorescence test instrument is equipped with sample-adding unit in the left side of mounting platform.
4. a kind of multichannel dry type Immunofluorescence test instrument according to claim 3, it is characterised in that：The multichannel is done
Formula Immunofluorescence test instrument is also equipped with sample and reagent unit on the left of mounting platform.
5. a kind of multichannel dry type Immunofluorescence test instrument according to claim 4, it is characterised in that：The mounting platform
On be additionally provided with display screen, control mainboard, printer.
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| CN201610351351.6A CN105866452B (en) | 2016-05-24 | 2016-05-24 | A kind of multichannel dry type Immunofluorescence test instrument |
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| CN201610351351.6A CN105866452B (en) | 2016-05-24 | 2016-05-24 | A kind of multichannel dry type Immunofluorescence test instrument |
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| CN105866452B true CN105866452B (en) | 2018-06-22 |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106680494B (en) * | 2017-02-28 | 2018-12-07 | 山东麦田生物技术有限公司 | Multiple immunochromatography quantitative analysis instrument |
| CN107490703A (en) * | 2017-08-02 | 2017-12-19 | 南京岚煜生物科技有限公司 | A kind of multichannel Immunofluorescence test device |
| CN107907697B (en) * | 2017-11-10 | 2020-02-07 | 深圳市金准生物医学工程有限公司 | Automatic card withdrawing mechanism and single-channel fluorescence immunoassay analyzer |
| CN108469520B (en) * | 2018-02-09 | 2020-12-04 | 广东优尼德生物科技有限公司 | Dry-type immunochromatography detector and detection method thereof |
| CN108896777A (en) * | 2018-08-20 | 2018-11-27 | 基蛋生物科技股份有限公司 | biochemical analyzer |
| CN111308105A (en) * | 2019-11-19 | 2020-06-19 | 长沙市鹏瑞生物科技有限公司 | Reagent card detector |
| CN114113620B (en) * | 2022-01-26 | 2022-03-29 | 山东康华生物医疗科技股份有限公司 | Card feeding and discharging mechanism for fluorescence immunoassay quantitative analyzer core |
| CN114113574B (en) * | 2022-01-26 | 2022-04-19 | 山东康华生物医疗科技股份有限公司 | Compact integrated multichannel fluorescence immunoassay quantitative analyzer core |
| CN114113619B (en) * | 2022-01-26 | 2022-03-29 | 山东康华生物医疗科技股份有限公司 | Transport mechanism for fluorescence immunoassay quantitative analyzer core |
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| US6881579B2 (en) * | 2001-07-30 | 2005-04-19 | Agilent Technologies, Inc. | Sample processing apparatus and methods |
| CN201035594Y (en) * | 2007-05-30 | 2008-03-12 | 罗祖明 | Driving device for movement of outdoor unattended card-dispensing machine |
| CN202057669U (en) * | 2011-05-16 | 2011-11-30 | 长春迪瑞医疗科技股份有限公司 | Probe mechanism |
| CN204462176U (en) * | 2014-12-30 | 2015-07-08 | 深圳市汇松科技发展有限公司 | A kind of crashproof sample needle |
| CN204855378U (en) * | 2015-05-29 | 2015-12-09 | 广州蓝勃生物科技有限公司 | Multinomial mesh dry -type fluorescence detector of horizontal location carousel formula |
| CN204740255U (en) * | 2015-07-27 | 2015-11-04 | 嘉兴凯实生物科技有限公司 | Detect card conveyor |
| CN205643367U (en) * | 2016-05-24 | 2016-10-12 | 湖南迪赛生物科技有限公司 | Multichannel dry -type immunofluorescence detector |
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