CN204789606U - Autoinjection device of immunodetection analytical instrument - Google Patents
Autoinjection device of immunodetection analytical instrument Download PDFInfo
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- CN204789606U CN204789606U CN201520503556.2U CN201520503556U CN204789606U CN 204789606 U CN204789606 U CN 204789606U CN 201520503556 U CN201520503556 U CN 201520503556U CN 204789606 U CN204789606 U CN 204789606U
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Abstract
The utility model discloses an autoinjection device in the immunodetection analytical instrument is formed by advancing a kind step motor, piston assembly, liquid level inductor, sample suction head, control center subassembly, fixed snap ring, compressive rod assembly and translation motor sub -assembly. Its profitable effect is according to sample test project and quantity, each sample application of sample volume of automatic setting and sample bulk volume, and once sample and realize in order, in proper order that it carries out application of sample one by one to treat the project of examining has been overcome traditional single sample circuit and has been advanced shortcomings such as device work length consuming time, inefficiency, the error of appearance is big, and quick for realizing, accurate, the synchronous assay of many indexs and report provide one and simple and convenient reliable have advanced the sample prescription formula, are fit for instant the measuring.
Description
Technical field
The utility model relates to immune detection technical field of analytical instruments, particularly a kind of automatic sampling apparatus of the immune detection analytical instrument immediately detected for in-vitro diagnosis, food security.
Background technology
Immunoassay technology refers to and utilizes the specific principle of immune response, the various determination and analysis technology of foundation.It is widely used in life science.Immune detection analytical instrument is the analytical instrument for measuring special molecular in the samples such as body fluid, serum, blood plasma, whole blood, generally comprises the steps such as sample introduction, mixing, temperature control, reaction, cleaning, developer, detection analysis.
Be below the sample loading alternative in existing several detection system:
1. immediately detecting at POCT(, PointofCareTesting) in class detection system, the sample of each patient is an operation unit.The project kind that each operation unit measures is different, quantity not etc. (from 1 to more than 10, generally all below 8), needed for each index, sample size is not identical yet.The project to be measured how realizing same patient is at a short as far as possible accurate application of sample of time inter-sync, and synchronization report, realize immediately detecting, loading methods and process are important controlling units.
In POCT class collaurum/fluorescence labeling class lateral chromatography Product checking process, for entry joint-detection, current application of sample pattern is comparatively extensive, its structure is the sample introduction end having different Indexs measure bar a sample well perimeter distribution, an application of sample in this sample well, then sample have been divided a word with a hyphen at the end of a line entry Parallel testing to nitrocellulose filter conversion zone by capillary action from chromatography strip sample introduction end, and the input mode as the detection of drugs class, HBV antigen, antibody test is all like this.Even if the initial application of sample of this input mode is accurate, but secondary distribution to the sample of each test event be difficult to accomplish accurately with accurately.Because projects sample end position is different, transfer ability is different, and transmission speed is different, causes multifarious change, and quantitative accuracy can not ensure.Therefore this input mode can not be satisfied the demand the project indicator application of sample needs of accurate quantitative analysis.
2.Luminex system is another kind of multi objective synchronous detecting method.Its input mode, after the fluorescence-encoded magnetic particle of index to be tested and fluorescent marker being mixed in advance in advance, once adds the sample of certain volume, react the regular hour after mixing, wash and test, completing detection in this potpourri.Due to this kind of system instrument complex structure, instrument and expensive reagents, be also not suitable for POCT Site Detection needs.
For realizing fast, multi objective Synchronization Analysis and report, and meet the requirement of the random project of each detecting unit and index quantity, need to set up accurately, the operating system of parallel, fast allocation sample, to meet the accurate application of sample needs of multi objective in instant testing process.
Utility model content
The purpose of this utility model is that the automatic sampling apparatus providing a kind of active immunity to detect analytical instrument is to realize quick, multi objective Synchronization Analysis application of sample demand.
For realizing above-mentioned technical purpose, reach above-mentioned technique effect, the present invention is achieved through the following technical solutions:
The utility model discloses automatic sampling apparatus in a kind of immune detection analytical instrument, comprise sample suction nozzle, piston component, sample introduction step motor, fixing snap ring, translation motor assembly and control center's assembly, sample suction nozzle is placed on below piston component, sample introduction step motor control piston assembly moves up and down, piston component is connected with translation motor assembly by fixing snap ring, and control center's assembly sends displacement commands and drives sample introduction step motor, translation motor assembly to perform sample introduction operation.
Preferably, also comprise the depression bar assembly be positioned at above sample suction nozzle, depression bar assembly comprises depression bar and pressure ring, and depression bar is positioned at below pressure ring.
Wherein, piston component comprises plunger shaft outer wall, piston core, piston end headgear head, and piston core is positioned at the outer pars intramuralis of plunger shaft, and piston end headgear head is positioned at bottom plunger shaft outer wall.
Wherein, translation motor assembly comprises left and right translation motor, anterior-posterior translation motor and upper and lower translation motor, and the axle head of left and right translation motor, anterior-posterior translation motor and upper and lower translation motor is all connected with crossbeam, and piston component is connected with crossbeam by fixing snap ring.
Wherein, plunger shaft outer wall is provided with liquid level sensor.
Further, also comprise scanner, it is connected with control center assembly.
The utility model has following beneficial effect:
1. the utility model gathers required Detection Information by control center's assembly, according to the difference of test item, number, calculate the required total number of samples detected, disposablely complete the long-pending sampling of required population of samples, avoid and repeatedly sample caused time waste and sample contamination.
2. can be completed the sample pipetting volume in horizontal plane by translation motor assembly fast and accurately, move back sample task, efficiently, rapidly can complete Detection task, avoid that single samples repeatedly, time caused by application of sample waits for the poor efficiency caused.
3. the analysis of measurement information is treated by control center's assembly, intelligently can complete single to multiple Indexs measure, improve traditional manual and detect, streamline consumes long detection time, the feature that personal error is large, reduces working time and the energy of staff greatly.
Accompanying drawing explanation
Fig. 1 is structural representation of the present utility model.
Primary clustering symbol description:
1: sample introduction step motor, 2: plunger shaft outer wall, 3: piston core, 4: piston end headgear head, 5: sample suction nozzle, 6: control center's assembly, 7: pressure ring, 8: depression bar, 9: fixing snap ring, 10: left and right translation motor, 11: anterior-posterior translation motor, 12: upper and lower translation motor, 13: crossbeam.
Embodiment
In order to make the purpose of this utility model, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the utility model is further elaborated.
As shown in Figure 1, the utility model discloses automatic sampling apparatus in a kind of immune detection analytical instrument, comprise sample introduction step motor 1, piston component, sample suction nozzle 5, control center's assembly 6, depression bar assembly, fixing snap ring 9, translation motor assembly, liquid level sensor (not shown), scanner (not shown).
Piston component includes plunger shaft outer wall 2, piston core 3, piston end headgear head 4, it is inner that piston core 3 is positioned at plunger shaft outer wall 2, piston end headgear head 4 is positioned at bottom plunger shaft outer wall 2, depression bar assembly includes pressure ring 7 and depression bar 8, depression bar 8 is positioned at below pressure ring 7, translation motor assembly includes left and right translation motor 10, anterior-posterior translation motor 11 and upper and lower translation motor 12, and the axle head of left and right translation motor 10, anterior-posterior translation motor 11 and upper and lower translation motor 12 is all connected with crossbeam 13.
Its process of installing is as follows:
Control center's assembly 6 is connected with sample introduction step motor 1 by data line, sample suction nozzle 5 is placed on below piston component, sample introduction step motor 1 is connected with piston component, piston component is connected with the axle head crossbeam 13 of left and right translation motor 10, anterior-posterior translation motor 11 and upper and lower translation motor 12 by fixing snap ring 9, plunger shaft outer wall 2 installs liquid level sensor, finally scanner is connected with control center assembly 6.
Below in conjunction with one group of thyroid hormone TSH, T
3, FT
3, T
4, FT
4the embodiment of five integrated detector tube parallel detection application of samples describes the course of work of the present utility model.
1, patient specimen bar code is read in control center's assembly 6 by scanner.
2, by patient test event TSH, T
3, FT
3, T
4, FT
4integrated detector tube is pressed tandem by scanner successively in order and is read test item bar code, bar code information is reached control center's assembly 6.
3, control center's assembly 6 checks in TSH, T under this patient identification code by specification of an item
3, FT
3, T
4, FT
4respectively need sample size to be respectively 100 μ L, 40 μ L, 40 μ L, 40 μ L, 40 μ L, add surplus capacity (sample suction nozzle dead space) 20 μ L, draw and need sampling gross sample amount 240 μ L.
4, sample intelligence is reached sample introduction step motor 1 by data line by control center's assembly 6.
5, sample introduction step motor 1 is inserted in sample suction nozzle 5 according to the order-driven piston component of control center's assembly 6, then moves to above sample hose position and drive upper and lower translation motor 12 in sample hose insertion sample suitable for reading.
6, liquid level sensor induction liquid level, under liquid level, 2mm inhales sample, sample size 240 μ L needed for sucking-off.
7, left and right translation motor 10 and anterior-posterior translation motor 11 Quality control suction nozzle 5 move to first integrated detector tube position of TSH project, and the descending setting shift length of sample introduction step motor 1, adds 100 μ L in the integrated detector tube of TSH project.Then sample suction nozzle 5 is moved to second T by left and right translation motor 10 and anterior-posterior translation motor 11
3the integrated detector tube position of project, adds 40 μ L wherein.So in order successively to FT
3, T
4, FT
4add volume required in the integrated detector tube of projects, until application of sample is complete, complete the TSH to same patient, T
3, FT
3, T
4, FT
4integrated detector tube continuously, automatic sample one by one.
8, complete after a whole project application of sample of sample, sample suction nozzle 5 abandoned by pressure ring 7 and depression bar 8.
The step repeating above 1 ~ 8 performs next sample project application of sample to be checked.
To sum up, the utility model is by intelligent sample introduction and distribution, the sample introduction of any number of entry and project arbitrary volume can be realized, realize disposable sampling, meet the sample introduction of batch testing projects combo, for realizing fast, accurately, multi objective Synchronization Analysis and report provide more easy reliable input mode, is applicable to instant detection.
The above; be only the utility model preferably embodiment; but protection domain of the present utility model is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the utility model discloses; the change that can expect easily or replacement, all should be encompassed within protection domain of the present utility model.
Claims (6)
1. the automatic sampling apparatus of immune detection analytical instrument, it is characterized in that: comprise sample suction nozzle, piston component, sample introduction step motor, fixing snap ring, translation motor assembly and control center's assembly, described sample suction nozzle is placed on below piston component, described sample introduction step motor control piston assembly moves up and down, described piston component is connected with translation motor assembly by fixing snap ring, and described control center's assembly sends displacement commands and drives sample introduction step motor, translation motor assembly to perform sample introduction operation.
2. the automatic sampling apparatus of immune detection analytical instrument as claimed in claim 1, it is characterized in that: also comprise the depression bar assembly be positioned at above sample suction nozzle, described depression bar assembly comprises depression bar and pressure ring, and described depression bar is positioned at below pressure ring.
3. the automatic sampling apparatus of immune detection analytical instrument as claimed in claim 1 or 2, it is characterized in that: described piston component comprises plunger shaft outer wall, piston core, piston end headgear head, described piston core is positioned at the outer pars intramuralis of plunger shaft, and piston end headgear head is positioned at bottom plunger shaft outer wall.
4. the automatic sampling apparatus of immune detection analytical instrument as claimed in claim 1 or 2, it is characterized in that: described translation motor assembly comprises left and right translation motor, anterior-posterior translation motor and upper and lower translation motor, the axle head of described left and right translation motor, anterior-posterior translation motor and upper and lower translation motor is all connected with crossbeam, and described piston component is connected with crossbeam by fixing snap ring.
5. the automatic sampling apparatus of immune detection analytical instrument as claimed in claim 3, is characterized in that: described plunger shaft outer wall is provided with liquid level sensor.
6. the automatic sampling apparatus of immune detection analytical instrument as claimed in claim 1 or 2, is characterized in that: also comprise scanner, and it is connected with control center assembly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520503556.2U CN204789606U (en) | 2015-07-14 | 2015-07-14 | Autoinjection device of immunodetection analytical instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520503556.2U CN204789606U (en) | 2015-07-14 | 2015-07-14 | Autoinjection device of immunodetection analytical instrument |
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| CN204789606U true CN204789606U (en) | 2015-11-18 |
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| CN201520503556.2U Active CN204789606U (en) | 2015-07-14 | 2015-07-14 | Autoinjection device of immunodetection analytical instrument |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106680523A (en) * | 2017-03-09 | 2017-05-17 | 厦门先明生物技术有限公司 | Linear propulsion and parallel processing reaction device for integrated reagent group |
| CN109444450A (en) * | 2018-12-27 | 2019-03-08 | 厦门先明生物技术有限公司 | A kind of whole blood sample automatic sampling apparatus |
| CN111487090A (en) * | 2019-11-14 | 2020-08-04 | 湖南爱威医疗科技有限公司 | Sample suction and sample application device |
-
2015
- 2015-07-14 CN CN201520503556.2U patent/CN204789606U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106680523A (en) * | 2017-03-09 | 2017-05-17 | 厦门先明生物技术有限公司 | Linear propulsion and parallel processing reaction device for integrated reagent group |
| CN109444450A (en) * | 2018-12-27 | 2019-03-08 | 厦门先明生物技术有限公司 | A kind of whole blood sample automatic sampling apparatus |
| CN109444450B (en) * | 2018-12-27 | 2022-05-17 | 厦门先明生物技术有限公司 | Whole blood sample autoinjection device |
| CN111487090A (en) * | 2019-11-14 | 2020-08-04 | 湖南爱威医疗科技有限公司 | Sample suction and sample application device |
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