CN109142709B - Puncture pipetting device of time-resolved fluoroimmunoassay analyzer - Google Patents

Puncture pipetting device of time-resolved fluoroimmunoassay analyzer Download PDF

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Publication number
CN109142709B
CN109142709B CN201811016241.XA CN201811016241A CN109142709B CN 109142709 B CN109142709 B CN 109142709B CN 201811016241 A CN201811016241 A CN 201811016241A CN 109142709 B CN109142709 B CN 109142709B
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pipetting
puncture
withdrawal
assembly
plate
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CN201811016241.XA
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CN109142709A (en
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李根平
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Guangzhou Biokey Health Technology Co ltd
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Guangzhou Biokey Health Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The invention discloses a puncture pipetting device of a time-resolved fluoroimmunoassay analyzer, wherein a pipetting withdrawal tube assembly and a withdrawal needle head selection assembly are both arranged at the middle lower part of the front surface of a large sliding plate; the puncture pipetting stepper motor is vertically arranged on the back of the frame, and an output shaft of the puncture pipetting stepper motor faces upwards and is in transmission connection with a screw in the puncture pipetting screw transmission assembly through the puncture pipetting synchronous belt assembly; the nut in the puncture pipetting screw transmission assembly is arranged on the back of the large sliding plate, the puncture pipetting stepper motor drives the screw to rotate, and the nut matched with the screw drives the large sliding plate to slide up and down, so that the pipetting withdrawal assembly and the withdrawal needle head selection assembly are connected to move up and down; the needle withdrawing selection assembly is inserted into the pipetting tube withdrawing assembly on the large sliding plate, so that the pipetting tube withdrawing device can puncture and remove liquid in the same mechanism, is simple and compact in structure and low in cost, is beneficial to simplifying the inspection process, and is very suitable for use, popularization and popularization of medical institutions in China.

Description

Puncture pipetting device of time-resolved fluoroimmunoassay analyzer
Technical Field
The invention relates to the field of time-resolved fluoroimmunoassay instruments used in the industries of in-vitro diagnosis and biomedicine, animal epidemic disease, food safety, drug screening and the like, in particular to a puncture pipetting device of a time-resolved fluoroimmunoassay instrument.
Background
POCT instant test (Point of Care Testing) is an important development direction of the in vitro diagnosis industry marking immunity technology in recent years and is the fastest growing branch. The technologies involved in POCT are diverse and broadly classified into simple color development, enzyme labeling, immunoassay, optical and electrical biosensors, electrochemical detection, spectrophotometry, biochips, and the like.
The development history of the labeling immune technology is hundreds of years, and the detection method of the labeling immune technology can be divided into: 1. radioimmunoassay, immunoradiometric assay (RIA, IRMA); 2. fluorescence Immunoassay (FIA); 3. enzyme Immunoassay (EIA); 4. gold-labeled immunoassay; 5. bioluminescence Immunoassay (BIA); 6. enzyme-fluorescence immunoassay (E-CIA); 7. chemiluminescent immunoassay (CLIA); 8. time Resolved Fluoroimmunoassay (TRFIA); 9. electrochemiluminescence immunoassay (ECLIA).
Time-resolved fluorescence immunoassay (TRFIA) adopts lanthanide chelate europium, terbium, samarium and dysprosium as markers, has wider excitation spectrum and narrower emission spectrum, and is favorable for reducing background and improving sensitivity; the ultraviolet excitation has the advantages of higher quantum yield, larger Stokes displacement, avoidance of superposition of excitation spectrum and fluorescence emission spectrum and the spectrum emitted by biological matrix, long fluorescence decay time and the like, and has wider detection range and better specificity than the traditional fluorescent substance.
The basic principle of the time-resolved fluorescence immunoassay instrument is that an antibody is marked by rare earth elements to prepare a reagent, the reagent excites fluorescence under the irradiation of a specific light source, the background interference fluorescence is eliminated after a period of time delay, namely the required fluorescence emitted by the marker is obtained, and the fluorescence is subjected to optical analysis, so that diagnosis can be made.
However, in some of the time-resolved immunoassay analyzers on the market at present, the steps of puncturing and pipetting the reagent strips are basically implemented by adopting more than two mechanisms, so that the structure is complex, the cost is high, and the inspection process is complex.
Disclosure of Invention
In order to solve the technical problems, the invention provides a puncture pipetting device of a time-resolved fluoroimmunoassay analyzer, which has simple and compact structure and low cost, and is beneficial to simplifying the inspection process.
The technical scheme of the invention is as follows: a puncture pipetting device of a time-resolved fluoroimmunoassay analyzer comprises a puncture pipetting stepper motor, a puncture pipetting synchronous belt assembly, a puncture pipetting screw transmission assembly, a pipetting withdrawal assembly, a withdrawal needle selection assembly, a puncture pipetting guide rail sliding block assembly and a large sliding plate; wherein, the pipetting withdrawal tube component and the withdrawal needle head selection component are both arranged at the middle lower part of the front surface of the large sliding plate; the back of the large sliding plate is connected with a sliding block in the puncture pipetting guide rail sliding block assembly through a screw, and two guide rails in the puncture pipetting guide rail sliding block assembly are vertically fixed on the front of the frame through screw intervals; the puncture pipetting stepper motor is vertically arranged on the back of the frame through a corresponding fixing piece, and an output shaft of the puncture pipetting stepper motor is upwards arranged and connected with one synchronous pulley in the puncture pipetting synchronous belt assembly through a corresponding bearing; the screw in the puncture pipetting screw transmission assembly is also vertically arranged on the back of the frame through a corresponding bearing and a fixing piece, and the upper end of the screw is connected with the other synchronous pulley in the puncture pipetting synchronous belt assembly through a corresponding bearing; nuts in the puncture pipetting screw transmission assembly are arranged on the back surface of the large sliding plate through corresponding fixing pieces; the synchronous belt in the puncture pipetting synchronous belt assembly is sleeved on the two synchronous pulleys and is used for driving the screw rod to rotate under the drive of the puncture pipetting stepper motor, and the nut matched with the screw rod drives the large sliding plate and the sliding block on the back of the large sliding plate to slide up and down along the guide rail, so that the pipetting withdrawal assembly and the withdrawal needle head selection assembly which are arranged on the front of the large sliding plate integrally move up and down.
The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer comprises: the nut is located on the longitudinal centerline of the large slide plate.
The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer comprises: the pipetting withdrawal assembly comprises a pipetting withdrawal motor fixing plate, a pipetting withdrawal screw motor, a pipetting withdrawal guide rail slide block assembly, a small slide plate, an injector push plate, a pipetting withdrawal motor nut, a plurality of puncture needles, an injector fixing plate and a plurality of pipetting injectors; the pipetting withdrawal motor fixing plate is transversely and vertically fixed on the front surface of the large sliding plate, the pipetting withdrawal screw motor is arranged on the pipetting withdrawal motor fixing plate, and the screw rod of the pipetting withdrawal screw motor passes through the pipetting withdrawal motor fixing plate to be vertically downwards arranged; the two guide rails in the pipetting-and-withdrawal-rail slide block assembly are vertically fixed on the front surface of a large slide plate below a pipetting-and-withdrawal-motor fixing plate at intervals through screws, the back surface of a small slide plate is connected with a slide block in the pipetting-and-withdrawal-rail slide block assembly, the ejector push plate is fixed on the top of the small slide plate, and a pipetting-and-withdrawal-motor nut is arranged on the ejector push plate and matched with the screw of the pipetting-and-withdrawal-screw motor; the puncture needles are vertically fixed on the bottom surface of the small sliding plate at intervals; the injector fixing plate is positioned below the pipetting withdrawal motor fixing plate and is connected with the pipetting withdrawal motor fixing plate through two upright posts; the plurality of pipetting injectors are vertically arranged on the top surface of the injector fixing plate at intervals, and a plurality of clamping grooves which are adapted to be clamped at the tail parts of the plurality of pipetting injectors are formed in the front edge of the injector push plate.
The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer comprises: the front of the large sliding plate below the fixing plate of the pipetting withdrawal motor is connected with an optocoupler sensor through a corresponding fixing piece for sensing the up-down position of the injector push plate.
The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer comprises: the needle withdrawing selection assembly comprises a plurality of needle withdrawing columns, a plurality of needle withdrawing plates, a needle withdrawing stepping motor, a needle withdrawing synchronous belt assembly and a needle withdrawing guide rail sliding block assembly; two needle withdrawing columns are arranged on the syringe fixing plate at the rear of each pipetting syringe through corresponding linear bearings, a spring is sleeved on the upper half part of each needle withdrawing column, the lower ends of the two needle withdrawing columns are connected with a needle withdrawing plate, and the front end of the needle withdrawing plate is provided with a notch adapted to withdraw the head needle of the pipetting syringe; the needle withdrawing stepping motor is transversely and inwards connected to one side of the small sliding plate through a corresponding fixing piece, an output shaft of the needle withdrawing stepping motor is connected with one synchronous pulley in a needle withdrawing synchronous belt assembly through a corresponding bearing, and the other synchronous pulley in the needle withdrawing synchronous belt assembly is connected to the other side of the small sliding plate through a corresponding bearing and a connecting shaft; the guide rail in the needle withdrawing guide rail slide block assembly is transversely fixed at the lower end of the front face of the small sliding plate through a screw, the slide block in the needle withdrawing guide rail slide block assembly is connected with a synchronous belt in the needle withdrawing synchronous belt assembly through a corresponding connecting piece, and the synchronous belt is sleeved on two synchronous pulleys in the needle withdrawing synchronous belt assembly.
According to the puncture pipetting device of the time-resolved fluoroimmunoassay analyzer, as the pipetting withdrawal needle selection assembly is inserted into the pipetting withdrawal tube assembly on the large sliding plate, the puncture and pipetting can be realized in the same mechanism, the structure is simple and compact, the cost is low, the simplification of the inspection process is facilitated, the device is particularly suitable for using the instant reagent, one or more samples can be detected at the same time, the sample consumption is less, the operation is simple and rapid, the result can be obtained in 30 minutes, the waiting time of a patient is greatly reduced, and the detection result is more stable; is very suitable for medical institutions in China to use, popularize and popularize.
Drawings
FIG. 1 is a perspective view of an embodiment of a lancing pipetting device for a time resolved fluoroimmunoassay analyzer of the present invention;
FIG. 2 is an enlarged perspective view of the pipette back assembly of FIG. 1 of the present invention;
fig. 3 is an enlarged perspective view of the retracting needle selection assembly of fig. 1 of the present invention.
Description of the embodiments
The following detailed description and examples of the invention are presented in conjunction with the drawings, and the described examples are intended to illustrate the invention and not to limit the invention to the specific embodiments.
Referring to fig. 1, fig. 1 is a perspective view of an embodiment of a puncture pipetting device of a time-resolved fluoroimmunoassay analyzer according to the present invention, wherein the puncture pipetting device 4 includes a puncture pipetting stepper motor 41, a puncture pipetting synchronous belt assembly 42, a puncture pipetting screw drive assembly 43, a pipetting withdrawal tube assembly 44, a withdrawal needle selection assembly 45, a puncture pipetting rail slide assembly (not shown) and a large slide plate 46; specific:
the pipetting withdrawal tube assembly 44 and the withdrawal needle selection assembly 45 are both mounted on the front middle lower part of the large slide plate 46; the back of the large sliding plate 46 is connected with a sliding block in a puncture pipetting guide rail sliding block assembly through a screw, and two guide rails in the puncture pipetting guide rail sliding block assembly are vertically fixed on the front of a vertical plate (not shown in the figure and the same below) of the instrument bracket through screw intervals; the puncture pipetting stepper motor 41 is vertically arranged on the back of the vertical plate of the instrument bracket through a corresponding fixing piece, and an output shaft of the puncture pipetting stepper motor 41 is upwards arranged and is connected with one synchronous pulley in the puncture pipetting synchronous belt assembly 42 through a corresponding bearing;
the screw in the puncture pipetting screw transmission assembly 43 is also vertically arranged on the back of the vertical plate of the instrument bracket through a corresponding bearing and a fixing piece, and the upper end of the screw is connected with the other synchronous pulley in the puncture pipetting synchronous belt assembly 42 through a corresponding bearing; nuts in the puncture pipetting screw drive assembly 43 are mounted on the back side of the large slide plate 46 via corresponding fixtures, and the nuts are located on the longitudinal axis of the large slide plate 46; the synchronous belt in the puncture pipetting synchronous belt assembly 42 is sleeved on the two synchronous pulleys, and is used for driving a screw rod to rotate under the drive of the puncture pipetting stepper motor 41, and driving a large sliding plate 46 and a sliding block on the back of the large sliding plate 46 to slide up and down along a guide rail through a nut matched with the screw rod, so that the pipetting withdrawal assembly 44 and the needle withdrawal selection assembly 45 which are arranged on the front of the large sliding plate 46 integrally move up and down, and the actions of puncture, pipetting, selective needle withdrawal and the like are completed according to detection requirements.
Referring now to fig. 2 and 3, fig. 2 is an enlarged perspective view of the pipette withdrawal assembly of fig. 1 of the present invention, and fig. 3 is an enlarged perspective view of the withdrawal needle selection assembly of fig. 1 of the present invention; specifically, the pipette withdrawal assembly 44 includes a pipette withdrawal motor fixing plate 442, a pipette withdrawal screw motor 441, a pipette withdrawal guide rail slider assembly 444, a small sliding plate 451, a syringe push plate 452, a pipette withdrawal motor nut 458, a plurality of puncture needles 456, a syringe fixing plate 443, a plurality of pipette syringes 445, and an optocoupler sensor 457; specific:
the pipette back motor fixing plate 442 is transversely and vertically fixed on the front surface of the large sliding plate 46, the pipette back screw motor 441 is installed on the pipette back motor fixing plate 442, and the screw 448 of the pipette back screw motor 441 is vertically arranged downwards through the pipette back motor fixing plate 442; the two guide rails in the pipetting-and-retracting-rail slide block assembly 444 are vertically fixed on the front surface of the large slide plate 46 below the pipetting-and-retracting-rail motor fixing plate 442 at intervals through screws, the back surface of the small slide plate 451 is connected with the slide blocks in the pipetting-and-retracting-rail slide block assembly 444, the injector push plate 452 is fixed on the top of the small slide plate 451, and the pipetting-and-retracting-rail motor nut 458 is mounted on the injector push plate 452 and matched with the screw rod 448 of the pipetting-and-retracting-rail screw motor 441 and is used for driving the injector push plate 452, the small slide plate 451 and the slide blocks on the back surface thereof to slide up and down along the guide rails through the pipetting-and-retracting-rail motor nut 458 matched with the screw rod 448 under the driving of the pipetting-and-retracting-rail screw motor 441; a plurality of puncture needles 456 are vertically fixed on the bottom surface of the small sliding plate 451 at intervals for completing the puncture according to the detection requirement;
the syringe fixing plate 443 is located below the pipetting withdrawal motor fixing plate 442 and connected to the pipetting withdrawal motor fixing plate 442 via two posts; the plurality of pipetting injectors 445 are vertically arranged on the top surface of the injector fixing plate 443 at intervals, and the front edge of the injector push plate 452 is provided with a plurality of clamping grooves which are adapted to be clamped at the tail parts of the plurality of pipetting injectors 445 and are used for completing pipetting according to detection requirements;
the optocoupler sensor 457 is connected to the front surface of the large slide plate 46 below the pipette back motor fixing plate 442 via a corresponding fixing member, and is used for sensing whether the injector push plate 452 is located in the upper position or the lower position.
Specifically, the needle retraction selection assembly 45 includes a plurality of needle retraction posts 446, a plurality of needle retraction plates 447, a needle retraction stepper motor 453, a needle retraction timing belt assembly 454, and a needle retraction guide slide assembly 455; wherein, two needle withdrawing columns 446 are arranged on the syringe fixing plate 443 behind each pipetting syringe 445 through corresponding linear bearings, a spring is sleeved on the upper half part of each needle withdrawing column 446 for enabling the needle withdrawing column 446 in the inner part to recover to the initial position without external force, the lower ends of the two needle withdrawing columns 446 are connected with a needle withdrawing plate 447, and the front end of the needle withdrawing plate 447 is provided with a notch adapted to withdraw the head needle of the pipetting syringe 445;
the needle withdrawing stepper motor 453 is transversely and inwardly connected to one side of the small sliding plate 451 via a corresponding fixing piece, and an output shaft of the needle withdrawing stepper motor 453 is connected with one synchronous pulley in the needle withdrawing synchronous belt assembly 454 via a corresponding bearing, and the other synchronous pulley in the needle withdrawing synchronous belt assembly 454 is connected to the other side of the small sliding plate 451 via a corresponding bearing and a connecting shaft; the guide rail in the needle withdrawing guide rail sliding block assembly 455 is transversely fixed at the front lower end of the small sliding plate 451 by a screw, the sliding block in the needle withdrawing guide rail sliding block assembly 455 is connected with the synchronous belt in the needle withdrawing synchronous belt assembly 454 by a corresponding connecting piece, and the synchronous belt is sleeved on two synchronous pulleys in the needle withdrawing synchronous belt assembly 454, and is used for driving the sliding block to move to the upper part of two needle withdrawing posts 446 behind a liquid-transferring injector 445 needing to withdraw needles by the synchronous belt under the driving of the needle withdrawing stepping motor 453, and driving the small sliding plate 451 and the sliding block to move downwards by a nut under the driving of the liquid-transferring tube withdrawing screw motor 441 so as to press the corresponding two needle withdrawing posts 446 and overcome the elasticity of the two springs, and the needle plate 447 at the lower ends of the two needle withdrawing posts 446 is linked to move downwards, so that the action of withdrawing the heads of the liquid-transferring injector 445 is completed, and when the small sliding plate 451 and the sliding block move upwards, the two springs sleeved on the two needle withdrawing posts 446 are utilized to move back to the needle plate 446.
It should be understood that the foregoing description is only of the preferred embodiments of the present invention and is not intended to limit the technical solutions of the present invention, and it should be understood that the foregoing may be added, substituted, altered or modified within the spirit and principle of the present invention by those skilled in the art, and all such added, substituted, altered or modified embodiments fall within the scope of the appended claims.

Claims (3)

1. The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer is characterized by comprising a puncture pipetting stepper motor, a puncture pipetting synchronous belt assembly, a puncture pipetting screw transmission assembly, a pipetting withdrawal tube assembly, a withdrawal needle head selection assembly, a puncture pipetting guide rail sliding block assembly and a large sliding plate; wherein, the pipetting withdrawal tube component and the withdrawal needle head selection component are both arranged at the middle lower part of the front surface of the large sliding plate; the back of the large sliding plate is connected with a sliding block in the puncture pipetting guide rail sliding block assembly through a screw, and two guide rails in the puncture pipetting guide rail sliding block assembly are vertically fixed on the front of the frame through screw intervals; the puncture pipetting stepper motor is vertically arranged on the back of the frame through a corresponding fixing piece, and an output shaft of the puncture pipetting stepper motor is upwards arranged and connected with one synchronous pulley in the puncture pipetting synchronous belt assembly through a corresponding bearing; the screw in the puncture pipetting screw transmission assembly is also vertically arranged on the back of the frame through a corresponding bearing and a fixing piece, and the upper end of the screw is connected with the other synchronous pulley in the puncture pipetting synchronous belt assembly through a corresponding bearing; nuts in the puncture pipetting screw transmission assembly are arranged on the back surface of the large sliding plate through corresponding fixing pieces; the synchronous belt in the puncture pipetting synchronous belt assembly is sleeved on the two synchronous pulleys and is used for driving the screw rod to rotate under the drive of the puncture pipetting stepper motor, and the nut matched with the screw rod drives the large sliding plate and the sliding block on the back of the large sliding plate to slide up and down along the guide rail, so that the pipetting withdrawal pipe assembly and the withdrawal needle head selection assembly which are arranged on the front of the large sliding plate integrally move up and down;
the pipetting withdrawal assembly comprises a pipetting withdrawal motor fixing plate, a pipetting withdrawal screw motor, a pipetting withdrawal guide rail slide block assembly, a small slide plate, an injector push plate, a pipetting withdrawal motor nut, a plurality of puncture needles, an injector fixing plate and a plurality of pipetting injectors; the pipetting withdrawal motor fixing plate is transversely and vertically fixed on the front surface of the large sliding plate, the pipetting withdrawal screw motor is arranged on the pipetting withdrawal motor fixing plate, and the screw rod of the pipetting withdrawal screw motor passes through the pipetting withdrawal motor fixing plate to be vertically downwards arranged; the two guide rails in the pipetting-and-withdrawal-rail slide block assembly are vertically fixed on the front surface of a large slide plate below a pipetting-and-withdrawal-motor fixing plate at intervals through screws, the back surface of a small slide plate is connected with a slide block in the pipetting-and-withdrawal-rail slide block assembly, the ejector push plate is fixed on the top of the small slide plate, and a pipetting-and-withdrawal-motor nut is arranged on the ejector push plate and matched with the screw of the pipetting-and-withdrawal-screw motor; the puncture needles are vertically fixed on the bottom surface of the small sliding plate at intervals; the injector fixing plate is positioned below the pipetting withdrawal motor fixing plate and is connected with the pipetting withdrawal motor fixing plate through two upright posts; the plurality of pipetting injectors are vertically arranged on the top surface of the injector fixing plate at intervals, and the front edge of the injector push plate is provided with a plurality of clamping grooves which are adapted to be clamped at the tail parts of the plurality of pipetting injectors;
the needle withdrawing selection assembly comprises a plurality of needle withdrawing columns, a plurality of needle withdrawing plates, a needle withdrawing stepping motor, a needle withdrawing synchronous belt assembly and a needle withdrawing guide rail sliding block assembly; two needle withdrawing columns are arranged on the syringe fixing plate at the rear of each pipetting syringe through corresponding linear bearings, a spring is sleeved on the upper half part of each needle withdrawing column, the lower ends of the two needle withdrawing columns are connected with a needle withdrawing plate, and the front end of the needle withdrawing plate is provided with a notch adapted to withdraw the head needle of the pipetting syringe; the needle withdrawing stepping motor is transversely and inwards connected to one side of the small sliding plate through a corresponding fixing piece, an output shaft of the needle withdrawing stepping motor is connected with one synchronous pulley in a needle withdrawing synchronous belt assembly through a corresponding bearing, and the other synchronous pulley in the needle withdrawing synchronous belt assembly is connected to the other side of the small sliding plate through a corresponding bearing and a connecting shaft; the guide rail in the needle withdrawing guide rail slide block assembly is transversely fixed at the lower end of the front face of the small sliding plate through a screw, the slide block in the needle withdrawing guide rail slide block assembly is connected with a synchronous belt in the needle withdrawing synchronous belt assembly through a corresponding connecting piece, and the synchronous belt is sleeved on two synchronous pulleys in the needle withdrawing synchronous belt assembly.
2. The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer according to claim 1, wherein: the nut is located on the longitudinal centerline of the large slide plate.
3. The puncture pipetting device of the time-resolved fluoroimmunoassay analyzer according to claim 1, wherein: the front of the large sliding plate below the fixing plate of the pipetting withdrawal motor is connected with an optocoupler sensor through a corresponding fixing piece for sensing the up-down position of the injector push plate.
CN201811016241.XA 2018-09-02 2018-09-02 Puncture pipetting device of time-resolved fluoroimmunoassay analyzer Active CN109142709B (en)

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CN113736627B (en) * 2021-09-30 2022-04-08 北京卓诚惠生生物科技股份有限公司 PCR system liquid injection device capable of automatically replacing syringe needle

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