CN204086119U - A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device - Google Patents
A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device Download PDFInfo
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- CN204086119U CN204086119U CN201420612406.0U CN201420612406U CN204086119U CN 204086119 U CN204086119 U CN 204086119U CN 201420612406 U CN201420612406 U CN 201420612406U CN 204086119 U CN204086119 U CN 204086119U
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- tooth bar
- shading
- transmission device
- light transmission
- motor
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Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
The utility model relates to a kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device, comprise tooth bar base, the tooth bar be movably installed on tooth bar base, drive the motor of racks turn, motor is connected with tooth bar, its middle rack offers the optics mounting hole installing optical filter and the baffle plate mounting hole installing baffle plate.After the shading that analyser application the utility model provides and light transmission device, when not being in detected state, baffle plate can block incident light, protects photomultiplier; Simultaneously owing to different optical member mounting holes being installed the optical filter of different wave length, therefore can control motor by master control board to drive tooth bar, realize the switching of the optical filter of different wave length, therefore analyser can detect polychromatic light after this device of application.
Description
Technical field
The utility model relates to time-resolved fluoroimmunoassay instrument field, more specifically, relates to a kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device.
Background technology
Time-resolved fluorescence (Time-Resolved Fluorescence is called for short TRF) immunoassay is a kind of microanalysis method grown up for nearly ten years.Its principle is as tracer with trivalent rare earth ions (as Eu europium, Sm samarium, Te terbium, dy dysprosium), labelled protein, polypeptide, hormone, antibody, nucleic acid probe or biologically active cell, question response system (as: antigen-antibody immune response, biotin-labeled pentylamine reaction, nucleic acid probe hybridization reaction, target cell and effector cell kill and wound reaction etc.) occur after, time-resolved fluorescence immunoassay instrument measures the fluorescence intensity in end product, judges the concentration of measured matter in reaction system with this.
As compared to other labeling method such as chemiluminescence, radio-immunity and enzyme linked immunological, TRF has clear superiority on sensitivity, stability and multiple labelling detect, and has a extensive future.Be mainly used in the inspection item needing high sensitivity and accurate quantitative analysis at present, comprise clinical infection disease and check (hepatitis B series, HCV, HIV etc.), Endocrinological inspection (thyroid gland series TSH etc., diabetes series Insulin etc., growth hormone hGH etc., woman produces class FSH etc.), tumor marker checks (AFP, CEA etc.), science of heredity checks, peripheral blood cell counts, cytolgical examination and various scientific research project.The clinical detection project of application TRF has reached 52 kinds, and has been applied in 24 kinds of research reagents at scientific research field TRF.Along with the development of laboratory medicine, can get more and more to the mensuration of trace, ultramicron, radioactive pollution problem simultaneously can more and more be taken seriously, and therefore, time-resolved fluorescence (TRF) immunoassay has more and more wide application space.
Prior art discloses a kind of time-resolved fluorescence immunoassay instrument, this analyser comprises luminous component, pallet and detection part, and wherein detection part comprises filter unit, detecting unit and photomultiplier, and detecting unit comprises optical filter.
Wherein use photomultiplier is the accuracy in order to improve detection, but this device is very responsive to light, can cause very large impact, even can destroy photomultiplier when beating light intensity of illumination thereon and being larger on the performance of photomultiplier.But analyser when in use, need to open instrument door to change reagent, during this period, extraneous light can enter analyser inside, impacts, thus affect the accuracy of testing result to the performance of photomultiplier.Therefore above-mentioned analyser is in actual application, and the accuracy of testing result is not high.
Utility model content
The utility model is the defect overcoming above-mentioned prior art; a kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device are provided; analyser is applied this device and can be protected the photomultiplier of inside, avoids extraneous light to cause damage to photomultiplier.
For solving the problems of the technologies described above, the technical solution of the utility model is as follows:
A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device, comprise tooth bar base, the tooth bar be movably installed on tooth bar base, the motor driving racks turn and the master control board that is connected with motor (3), motor is connected with tooth bar, its middle rack offers the optics mounting hole installing optical filter and the baffle plate mounting hole installing baffle plate.
For time-resolved fluoroimmunoassay instrument, generally comprise light path module, master control board (being master control board of the present utility model), lower light path module and power module, upper light path module, lower light path module are connected with master control board, power module respectively.Optical filtering submodule, photomultiplier and the detection sub-module wherein descending light path module to comprise to connect successively, when analyser is in detected state, incident light is by being incident to detection sub-module after optical filtering submodule, photomultiplier.Wherein optical filtering submodule comprises optical filter.When the shading that installation the utility model in analyser inside provides and light transmission device, first by motor and master control board, power module couples together, then on optics mounting hole optical filter and baffle plate being arranged on tooth bar respectively and baffle plate mounting hole, again shading and light transmission device are fixed, it should be noted that, need when being fixed to finely tune the installation site of shading and light transmission device, make incident light can by being incident to photomultiplier after the optical filter in shading and light transmission device, also the accuracy of position can be ensured by the accurate control of master control borad.
After the application shading that provides of the utility model and light transmission device, when analyser is in detected state, master control board controls motor and drives tooth bar, makes incident light can by being incident to photomultiplier after the optical filter in shading and light transmission device; When analyser is not in detected state, master control board controls motor and drives tooth bar, makes baffle plate block incident light, protects photomultiplier.
Preferably, tooth bar is specially with the connected mode of motor: motor is connected with gear by Timing Belt, and wheel and rack engages.
Preferably, described tooth bar is provided with sensitive film, tooth bar base is provided with the sensor detected the image on sensitive film, sensor is connected with master control board.Set up sensor, sensitive film, therefore when installation, needed sensor and master control board to couple together.The wherein relative displacement of data determination tooth bar that gathered by sensor of master control board, thus realize the accurate control to tooth bar relative displacement.
Preferably, described optics mounting hole is provided with multiple, and multiple optics mounting hole installs optical filter respectively.
Preferably, optical filter different optical member mounting holes installed has different wavelength.The analyser that prior art provides, generally can only detect monochromatic light.But analyser is after this device of application, different optical member mounting holes is installed the optical filter of different wave length, then control motor by master control board to drive tooth bar, realize the switching of the optical filter of different wave length, therefore analyser can detect polychromatic light after this device of application.
Preferably, described baffle plate mounting hole site is between any two optics mounting holes.
Preferably, described optics mounting hole comprises 4.
Preferably, described motor is installed fixing by electric baseboard.
After the shading that analyser application the utility model provides and light transmission device, when not being in detected state, baffle plate can block incident light, protects photomultiplier; Simultaneously owing to different optical member mounting holes being installed the optical filter of different wave length, therefore can control motor by master control board to drive tooth bar, realize the switching of the optical filter of different wave length, therefore analyser can detect polychromatic light after this device of application.
Accompanying drawing explanation
Fig. 1 is the structural representation of shading and light transmission device.
Embodiment
Below in conjunction with drawings and Examples, the technical solution of the utility model is described further.
Embodiment 1
As shown in Figure 1, shading and light transmission device comprise tooth bar base 1, the tooth bar 2 be movably installed on tooth bar base 1, the motor 3 driving tooth bar 2 to rotate and the master control board that is connected with motor 3, motor 3 is connected with tooth bar 2, motor 3 is installed fixing by electric baseboard 12, its middle rack 2 offers the optics mounting hole 5 installing optical filter 4 and the baffle plate mounting hole 7 installing baffle plate 6.
Optics mounting hole 5 is provided with multiple, and in the present embodiment, the quantity of optics mounting hole 5 is 4.Baffle plate mounting hole 7 is between any two optics mounting holes 5.
Its middle rack 2 is specially with the connected mode of motor 3: motor 2 is connected with gear 9 by Timing Belt 8, and gear 9 engages with tooth bar 2.
The analyser that prior art provides, generally comprises light path module, master control board, lower light path module and power module, and upper light path module, lower light path module are connected with master control board, power module respectively.Optical filtering submodule, photomultiplier and the detection sub-module wherein descending light path module to comprise to connect successively, when analyser is in detected state, incident light is by being incident to detection sub-module after optical filtering submodule, photomultiplier.Optical filtering submodule comprises optical filter 4.
When the shading that installation the utility model in analyser inside provides and light transmission device, first motor 2 and master control board, power module are coupled together, then optical filter 4 and baffle plate 6 are arranged on respectively the optics mounting hole 5 of tooth bar 2 with on baffle plate mounting hole 7, again shading and light transmission device are fixed, it should be noted that, needing when being fixed to finely tune the installation site of shading and light transmission device, making incident light can by being incident to photomultiplier after the optical filter 4 in shading and light transmission device.
After the shading that analyser application the utility model provides and light transmission device; when being in detected state; master control board controls motor 3 and drives tooth bar 2; make incident light can by being incident to photomultiplier after the optical filter 4 in shading and light transmission device; when analyser is not in detected state; master control board controls motor 3 and drives tooth bar 2, makes baffle plate 6 block incident light, protects photomultiplier.
In the present embodiment, different optical member mounting holes 5 is installed the optical filter 4 of different wave length.The analyser that prior art provides, generally can only detect monochromatic light.But analyser is after this device of application, by installing the optical filter 4 of different wave length on different optical member mounting holes 5, then control motor 3 pairs of tooth bars 2 by master control board to drive, realize the switching of the optical filter 4 of different wave length, therefore analyser can detect polychromatic light after this device of application.Further, baffle plate mounting hole 7, between any two optics mounting holes 5, can facilitate the switching between baffle plate mounting hole 7 and optics mounting hole 5, saves switching time.
In the present embodiment, tooth bar 2 is provided with sensitive film 10, tooth bar base 1 is provided with the sensor 11 detected the image on sensitive film 10, sensor 11 is connected with master control board.Set up sensor 11, sensitive film 10, when installation, needed sensor 11 and master control board to couple together.The wherein relative displacement of data determination tooth bar 2 that gathered by sensor 11 of master control board, thus realize the accurate control to tooth bar 2 relative displacement.
After the shading that analyser application the utility model provides and light transmission device, when not being in detected state, baffle plate can block incident light, protects photomultiplier; Simultaneously owing to different optical member mounting holes being installed the optical filter of different wave length, therefore can control motor by master control board to drive tooth bar, realize the switching of the optical filter of different wave length, therefore analyser can detect polychromatic light after this device of application.
Obviously, above-described embodiment of the present utility model is only for the utility model example is clearly described, and is not the restriction to embodiment of the present utility model.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.All do within spirit of the present utility model and principle any amendment, equivalent to replace and improvement etc., within the protection domain that all should be included in the utility model claim.
Claims (8)
1. the shading for time-resolved fluoroimmunoassay instrument and light transmission device, it is characterized in that: comprise tooth bar base (1), the tooth bar (2) be movably installed on tooth bar base (1), the master control board that drives tooth bar (2) motor (3) that rotates and be connected with motor (3), motor (3) is connected with tooth bar (2), its middle rack (2) offers the optics mounting hole (5) installing optical filter (4) and the baffle plate mounting hole (7) installing baffle plate (6).
2. the shading for time-resolved fluoroimmunoassay instrument according to claim 1 and light transmission device, it is characterized in that: tooth bar (2) is specially with the connected mode of motor (3): motor (3) is connected with gear (9) by Timing Belt (8), gear (9) engages with tooth bar (2).
3. the shading for time-resolved fluoroimmunoassay instrument according to claim 2 and light transmission device, it is characterized in that: described tooth bar (2) is provided with sensitive film (10), tooth bar base (1) is provided with the sensor (11) detected the image on sensitive film (10), sensor (11) is connected with master control board.
4. the shading for time-resolved fluoroimmunoassay instrument according to claim 1 and light transmission device, is characterized in that: described optics mounting hole (5) is provided with multiple, and multiple optics mounting hole (5) installs optical filter (4) respectively.
5. the shading for time-resolved fluoroimmunoassay instrument according to claim 4 and light transmission device, is characterized in that: the upper optical filter (4) installed of different optical member mounting holes (5) has different wavelength.
6. the shading for time-resolved fluoroimmunoassay instrument according to claim 4 and light transmission device, described baffle plate mounting hole (7) is positioned between any two optics mounting holes (5).
7. the shading for time-resolved fluoroimmunoassay instrument according to claim 4 and light transmission device, is characterized in that: described optics mounting hole (5) comprises 4.
8. the shading for time-resolved fluoroimmunoassay instrument according to any one of claim 1-7 and light transmission device, is characterized in that: described motor (3) is installed fixing by electric baseboard (12).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420612406.0U CN204086119U (en) | 2014-10-22 | 2014-10-22 | A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420612406.0U CN204086119U (en) | 2014-10-22 | 2014-10-22 | A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device |
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| CN204086119U true CN204086119U (en) | 2015-01-07 |
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| CN201420612406.0U Expired - Lifetime CN204086119U (en) | 2014-10-22 | 2014-10-22 | A kind of shading for time-resolved fluoroimmunoassay instrument and light transmission device |
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| CN (1) | CN204086119U (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109116535A (en) * | 2018-10-23 | 2019-01-01 | 温氏食品集团股份有限公司 | A kind of shade and shading control system of fluorescence microscope |
| US10288633B2 (en) | 2015-06-26 | 2019-05-14 | Abbott Laboratories | Reaction vessel moving member for moving reaction vessels from a processing track to a rotating device in a diagnostic analyzer |
| CN110530782A (en) * | 2019-09-25 | 2019-12-03 | 迈克医疗电子有限公司 | Eliminate the optical system and method for side-lobe signal interference |
| CN113418897A (en) * | 2021-06-17 | 2021-09-21 | 安徽建筑大学 | Fluorescent material excitation measuring device |
| CN113418941A (en) * | 2021-06-30 | 2021-09-21 | 深圳市福瑞康科技有限公司 | Darkroom subassembly and check out test set |
-
2014
- 2014-10-22 CN CN201420612406.0U patent/CN204086119U/en not_active Expired - Lifetime
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10288633B2 (en) | 2015-06-26 | 2019-05-14 | Abbott Laboratories | Reaction vessel moving member for moving reaction vessels from a processing track to a rotating device in a diagnostic analyzer |
| US11733257B2 (en) | 2015-06-26 | 2023-08-22 | Abbott Laboratories | Reaction vessel moving member for moving reaction vessels from a processing track to a rotating device in a diagnostic analzyer |
| CN109116535A (en) * | 2018-10-23 | 2019-01-01 | 温氏食品集团股份有限公司 | A kind of shade and shading control system of fluorescence microscope |
| CN110530782A (en) * | 2019-09-25 | 2019-12-03 | 迈克医疗电子有限公司 | Eliminate the optical system and method for side-lobe signal interference |
| CN110530782B (en) * | 2019-09-25 | 2024-05-07 | 迈克医疗电子有限公司 | Optical system and method for eliminating side lobe signal interference |
| CN113418897A (en) * | 2021-06-17 | 2021-09-21 | 安徽建筑大学 | Fluorescent material excitation measuring device |
| CN113418941A (en) * | 2021-06-30 | 2021-09-21 | 深圳市福瑞康科技有限公司 | Darkroom subassembly and check out test set |
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