CN106998787A - 通过改变硝酸同化路径减少烟草特异性亚硝胺 - Google Patents
通过改变硝酸同化路径减少烟草特异性亚硝胺 Download PDFInfo
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- CN106998787A CN106998787A CN201580049814.7A CN201580049814A CN106998787A CN 106998787 A CN106998787 A CN 106998787A CN 201580049814 A CN201580049814 A CN 201580049814A CN 106998787 A CN106998787 A CN 106998787A
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Classifications
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/245—Nitrosamines
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/20—Biochemical treatment
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
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- C—CHEMISTRY; METALLURGY
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- C12Y107/01—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with NAD+ or NADP+ as acceptor (1.7.1)
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| EP14194798.6 | 2014-11-25 | ||
| PCT/EP2015/071919 WO2016046288A1 (en) | 2014-09-26 | 2015-09-23 | Reducing tobacco specific nitrosamines through alteration of the nitrate assimilation pathway |
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| CN106998787A true CN106998787A (zh) | 2017-08-01 |
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| EP (1) | EP3198015A1 (https=) |
| JP (1) | JP6921740B2 (https=) |
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| CN108424922A (zh) * | 2018-04-20 | 2018-08-21 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e10基因错义突变体m271及其应用 |
| CN110747208A (zh) * | 2019-11-28 | 2020-02-04 | 海南大学 | 一种木薯硝酸还原酶基因及其过量表达载体的构建和抗病应用 |
| CN110819640A (zh) * | 2019-12-19 | 2020-02-21 | 中国烟草总公司郑州烟草研究院 | 烟草NtNRP1基因其应用 |
| CN116583176A (zh) * | 2020-12-09 | 2023-08-11 | 日本烟草产业株式会社 | 烟草植物及烟草制品 |
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| EP3280803B1 (en) | 2015-04-06 | 2021-05-26 | The Board of Trustees of the Leland Stanford Junior University | Chemically modified guide rnas for crispr/cas-mediated gene regulation |
| WO2016179356A1 (en) * | 2015-05-05 | 2016-11-10 | North Carolina State University | Methods and compositions for reducing the tobacco specific nitrosamine nnk in tobacco |
| US10767175B2 (en) | 2016-06-08 | 2020-09-08 | Agilent Technologies, Inc. | High specificity genome editing using chemically modified guide RNAs |
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| AR115022A1 (es) | 2018-03-28 | 2020-11-18 | Philip Morris Products Sa | Modulación del contenido de aminoácidos en una planta |
| AR115023A1 (es) | 2018-03-28 | 2020-11-18 | Philip Morris Products Sa | Modulación del contenido de azúcar reductor en una planta |
| GB201812603D0 (en) * | 2018-08-02 | 2018-09-19 | British American Tobacco Investments Ltd | Method |
| DE102018216970A1 (de) * | 2018-10-04 | 2020-04-09 | Robert Bosch Gmbh | Brennstoffeinspritzvorrichtung |
| US11976286B2 (en) * | 2018-12-30 | 2024-05-07 | Philip Morris Products S.A. | Modulation of nitrate levels in plants via mutation of nitrate reductase |
| WO2022192743A1 (en) * | 2021-03-11 | 2022-09-15 | Thermolife International, Llc | Enhanced nitrate, elemental metal, and amino acid compositions and methods of use |
| JP2022552638A (ja) | 2019-10-01 | 2022-12-19 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 植物における糖およびアミノ酸含有量の調節（ｓｕｌｔｒ３） |
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| CN115516098A (zh) * | 2020-01-17 | 2022-12-23 | 奥驰亚客户服务有限公司 | 与改进的氮利用效率有关的方法和组合物 |
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| JP2026506774A (ja) | 2023-02-02 | 2026-02-26 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 糖トランスポーターの調節 |
| EP4658670A1 (en) | 2023-02-02 | 2025-12-10 | Philip Morris Products S.A. | Modulation of genes coding for lysine ketoglutarate reductase |
| CN121335615A (zh) | 2023-06-29 | 2026-01-13 | 菲利普莫里斯生产公司 | 编码谷氨酸脱氢酶的基因的调节 |
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- 2015-09-23 BR BR112017003842-0A patent/BR112017003842B1/pt active IP Right Grant
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108424922A (zh) * | 2018-04-20 | 2018-08-21 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e10基因错义突变体m271及其应用 |
| CN108424922B (zh) * | 2018-04-20 | 2021-04-16 | 云南省烟草农业科学研究院 | 一种降低尼古丁转化率的cyp82e10基因错义突变体m271及其应用 |
| CN110747208A (zh) * | 2019-11-28 | 2020-02-04 | 海南大学 | 一种木薯硝酸还原酶基因及其过量表达载体的构建和抗病应用 |
| CN110747208B (zh) * | 2019-11-28 | 2022-04-22 | 海南大学 | 一种木薯硝酸还原酶基因及其过量表达载体的构建和抗病应用 |
| CN110819640A (zh) * | 2019-12-19 | 2020-02-21 | 中国烟草总公司郑州烟草研究院 | 烟草NtNRP1基因其应用 |
| CN110819640B (zh) * | 2019-12-19 | 2022-06-21 | 中国烟草总公司郑州烟草研究院 | 烟草NtNRP1基因其应用 |
| CN116583176A (zh) * | 2020-12-09 | 2023-08-11 | 日本烟草产业株式会社 | 烟草植物及烟草制品 |
| CN116583176B (zh) * | 2020-12-09 | 2024-12-31 | 日本烟草产业株式会社 | 烟草植物及烟草制品 |
Also Published As
| Publication number | Publication date |
|---|---|
| PH12017500313A1 (en) | 2017-07-17 |
| KR20170078599A (ko) | 2017-07-07 |
| RU2721799C2 (ru) | 2020-05-22 |
| JP2017529850A (ja) | 2017-10-12 |
| MX2017003932A (es) | 2017-06-30 |
| KR102524798B1 (ko) | 2023-04-24 |
| US11666082B2 (en) | 2023-06-06 |
| CO2017004076A2 (es) | 2017-09-20 |
| RU2017114356A3 (https=) | 2019-04-29 |
| RU2017114356A (ru) | 2018-10-29 |
| CA2959245A1 (en) | 2016-03-31 |
| WO2016046288A1 (en) | 2016-03-31 |
| BR112017003842B1 (pt) | 2024-02-20 |
| BR112017003842A2 (pt) | 2017-12-19 |
| EP3198015A1 (en) | 2017-08-02 |
| JP6921740B2 (ja) | 2021-08-18 |
| US20170303582A1 (en) | 2017-10-26 |
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