CN106924108A - A kind of whitening spot-removing creams - Google Patents

A kind of whitening spot-removing creams Download PDF

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Publication number
CN106924108A
CN106924108A CN201710078627.2A CN201710078627A CN106924108A CN 106924108 A CN106924108 A CN 106924108A CN 201710078627 A CN201710078627 A CN 201710078627A CN 106924108 A CN106924108 A CN 106924108A
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parts
whitening spot
emollient
whitening
thickener
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CN201710078627.2A
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CN106924108B (en
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史学东
杨深鹏
李文君
顾葵
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GUANGZHOU DEVA BIOTECHNOLOGY Co Ltd
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GUANGZHOU DEVA BIOTECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

Abstract

The invention discloses a kind of whitening spot-removing creams.By 4 butyl resorcinols and this 2 kinds of whitening compositions of glabridin and ultra-violet absorber in creams formula of the present invention(Ethylhexyl methoxy cinnamate), moisture-keeping crease-shedding composition(Sodium Hyaluronate, biological carbohydrate gum 1, hydroxy decyl ubiquinone)Reasonable compatibility is carried out, stimulation of the excessive ultraviolet radioactive to skin is reduced, the formation of melanin is prevented, and effectively protects skin, reach the effect of excellent whitening, nti-freckle, moisturizing;It is without any side effects without parabens preservative without mineral oil, it is adaptable to need all groups of daily skin care without essence in creams formula of the present invention.

Description

A kind of whitening spot-removing creams
Technical field
The present invention relates to cosmetic technical field, more particularly to a kind of whitening spot-removing creams.
Background technology
With advancing age, life stress is increasing, and along with external environmental, ultraviolet is to facial skin Injury is increasing, causes melanin constantly to precipitate, and skin becomes coarse, dark yellow, lacks moisture.Currently a popular use creams are applied The method of protection is smeared to carry out maintenance nursing to facial skin.
Creams are a kind of carriers of skin-care nutrient composition, and form is varied, there is oil-in-water type, water-in-oil type etc., wherein Oil-in-water type is more suitable for the daily nursing of skin.Whitening spot-removing majority is that based on moisturizing, whitening is dispelled on the basis of moisturizing Spot, anti-ageing maintenance work of waiting for a long time just can be more effective.
A large amount of work for having and exploring meaning have been done in order to solve the above problems, in industry;In the market is also emerged with each The creams of effect are planted, has certain curative effect to the whitening spot-removing of face.But the raw material of existing creams is main or part still uses work The composition of industry synthesis is more, and the material of a part of commercial synthesis may be to the skin irritant of a class crowd, Huo Zheling The material of a part of commercial synthesis may be to the skin irritant of another kind of crowd, so as to cause allergic and redness Phenomenon, and then skin is become more fragile sensitivity.
The content of the invention
Skin whitening, moisturizing, nti-freckle demand are disclosure satisfy that it is an object of the invention to provide a kind of, while again to skin Nonirritant creams.
The technical solution used in the present invention is:
A kind of whitening spot-removing creams, it is composed of the following components:Ethylhexyl methoxy cinnamate, 4- butyl resorcinol, Glabridin, hydroxy decyl ubiquinone, Sodium Hyaluronate, biological carbohydrate gum -1, tocopherol, dipotassium glycyrrhizinate, peony extract, to hydroxyl Benzoylformaldoxime, 1,2- hexylene glycols, emollient, thickener, emulsifying agent, water, butanediol.
A kind of whitening spot-removing creams, are made up of by weight following components:2~10 parts of ethylhexyl methoxy cinnamate, 0.1~1 part of 4- butyl resorcinol, 0.001~0.01 part of glabridin, 0.2~2 part of hydroxy decyl ubiquinone, Sodium Hyaluronate 0.03~0.3 part, biological 0.3~4 part of carbohydrate gum -1,0.2~2 part of tocopherol, 0.03~0.3 part of dipotassium glycyrrhizinate, peony carry Take 2~15 parts of thing, 0.1~0.6 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.05~0.5,15~35 parts of emollient, thickener 0.5~3 part, 1~8 part of emulsifying agent, 30~65 parts of water, 1~8 part of butanediol.
Preferably, a kind of whitening spot-removing creams, are made up of by weight following components:Ethylhexyl methoxy cinnamate 3 ~7 parts, 0.2~0.6 part of 4- butyl resorcinol, 0.002~0.006 part of glabridin, 0.3~1.8 part of hydroxy decyl ubiquinone, thoroughly Bright 0.05~0.25 part of sodium of matter acid, biological 0.5~3.5 part of carbohydrate gum -1,0.3~1.8 part of tocopherol, dipotassium glycyrrhizinate 0.05~ 0.25 part, 3~12 parts of peony extract, 0.2~0.5 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.1~0.5, emollient 20 ~30 parts, 1~2.5 part of thickener, 2~6 parts of emulsifying agent, 35~60 parts of water, 2~6 parts of butanediol.
It is further preferred that a kind of whitening spot-removing creams, are made up of by weight following components:Methoxy cinnamic acid ethyl 4~6 parts of own ester, 0.3~0.5 part of 4- butyl resorcinol, 0.003~0.005 part of glabridin, hydroxy decyl ubiquinone 0.5~1.5 Part, 0.1~0.2 part of Sodium Hyaluronate, biological 1~3 part of carbohydrate gum -1,0.5~1.5 part of tocopherol, dipotassium glycyrrhizinate 0.1~0.2 Part, 5~10 parts of peony extract, 0.3~0.4 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.2~0.4, emollient 22.5~ 28.5 parts, 1.5~2.25 parts of thickener, 3~5 parts of emulsifying agent, 40~55 parts of water, 3~5 parts of butanediol.
The emollient is made up of by weight following components:Propane diols 2~6, Butyrospermum parkii fruit fat 2~6, saualane 2 ~6, isohexadecane 5~8, ring five dimethyl silicone polymer 2~6, dimethyl silicone polymer 0.3~1.2, cetostearyl alcohol 1~ 3。
Preferably, the emollient is made up of by weight following components:Propane diols 3~5, Butyrospermum parkii fruit fat 3~5, Saualane 3~5, isohexadecane 6~7, ring five dimethyl silicone polymer 3~5, dimethyl silicone polymer 0.5~1, cetearyl alcohol Alcohol 1.5~2.5.
The thickener is at least one of xanthans, hydroxyethyl cellulose, SIMULGELTMNS thickeners.
The beneficial effects of the invention are as follows:
(1) present invention is by 4- butyl resorcinol and this 2 kinds of whitening compositions of glabridin and ultra-violet absorber (methoxyl group 2-Ethylhexyl cinnamate), three kinds of moisture-keeping crease-shedding compositions (Sodium Hyaluronate, biological carbohydrate gum -1, hydroxy decyl ubiquinone) carry out Reasonable 5, stimulation of the excessive ultraviolet radioactive to skin is reduced, the formation of melanin is prevented, and skin is effectively protected, reach excellent The effect of whitening, nti-freckle, moisturizing;
(2) without essence in creams formula of the present invention, without mineral oil, without parabens preservative, nothing Any side effect.
Specific embodiment
A kind of whitening spot-removing creams, it is composed of the following components:Ethylhexyl methoxy cinnamate, 4- butyl resorcinol, Glabridin, hydroxy decyl ubiquinone, Sodium Hyaluronate, biological carbohydrate gum -1, tocopherol, dipotassium glycyrrhizinate, peony extract, to hydroxyl Benzoylformaldoxime, 1,2- hexylene glycols, emollient, thickener, emulsifying agent, water, butanediol.
A kind of whitening spot-removing creams, are made up of by weight following components:2~10 parts of ethylhexyl methoxy cinnamate, 0.1~1 part of 4- butyl resorcinol, 0.001~0.01 part of glabridin, 0.2~2 part of hydroxy decyl ubiquinone, Sodium Hyaluronate 0.03~0.3 part, biological 0.3~4 part of carbohydrate gum -1,0.2~2 part of tocopherol, 0.03~0.3 part of dipotassium glycyrrhizinate, peony carry Take 2~15 parts of thing, 0.1~0.6 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.0.5~0.5,15~35 parts of emollient, thickener 0.5~3 part, 1~8 part of emulsifying agent, 30~65 parts of water, 1~8 part of butanediol.
Preferably, a kind of whitening spot-removing creams, its component is calculated as by weight:Ethylhexyl methoxy cinnamate 3~7 It is part, 0.2~0.6 part of 4- butyl resorcinol, 0.002~0.006 part of glabridin, 0.3~1.8 part of hydroxy decyl ubiquinone, transparent 0.05~0.25 part of sodium of matter acid, biological 0.5~3.5 part of carbohydrate gum -1,0.3~1.8 part of tocopherol, dipotassium glycyrrhizinate 0.05~ 0.25 part, 3~12 parts of peony extract, 0.2~0.5 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.1~0.5, emollient 20 ~30 parts, 1~2.5 part of thickener, 2~6 parts of emulsifying agent, 35~60 parts of water, 2~6 parts of butanediol.
It is further preferred that a kind of whitening spot-removing creams, its component is calculated as by weight:Ethylhexyl methoxy cinnamate 4~6 parts, 0.3~0.5 part of 4- butyl resorcinol, 0.003~0.005 part of glabridin, 0.5~1.5 part of hydroxy decyl ubiquinone, 0.1~0.2 part of Sodium Hyaluronate, biological 1~3 part of carbohydrate gum -1,0.5~1.5 part of tocopherol, 0.1~0.2 part of dipotassium glycyrrhizinate, 5~10 parts of peony extract, 0.3~0.4 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.2~0.4, emollient 22.5~ 28.5 parts, 1.5~2.25 parts of thickener, 3~5 parts of emulsifying agent, 40~55 parts of water, 3~5 parts of butanediol.
4- butyl resorcinol, glabridin and ethylhexyl methoxy cinnamate are carried out reasonable compatibility, energy by the present invention Stimulation of the excessive ultraviolet radioactive to skin is reduced, the formation of melanin is prevented, and effectively protects skin, reach whitening spot-removing Effect.4- butyl resorcinol can restrained effectively TYR enzyme and TRP-1 enzymes, activation point be hindered, so as to prevent melanin Formation.Glabridin can go deep into skin inside and keep high activity, whitening and high-efficiency antioxidant, can effectively suppress melanin life The activity of various enzymes during, particularly suppresses TYR enzyme activity.Ethylhexyl methoxy cinnamate is UV B areas Good absorption agent, can effectively prevent the ultraviolet of 280~310nm, and absorptivity is high, and non-stimulated to skin, and security is good.
The present invention is also carried out on the basis of above-mentioned whitening component with Sodium Hyaluronate, biological carbohydrate gum -1, hydroxy decyl ubiquinone Reasonable compatibility, realizes the effect that bright color and replenishing water and preserving moisture are repaired.Sodium Hyaluronate has high moisture retention, viscoplasticity and profit Slip, it not only can moisten skin smooth, also with stronger wrinkle-chasing function, can increase skin elasticity, and delaying skin declines Always.Biological carbohydrate gum -1 is the special polysaccharide in brown algae, a kind of NMF of natural origin, and it is very strong that it combines outlet capacity, i.e., Make also to show good soaking effect in the environment of low humidity, while forming ventilative sugared film in skin surface, prevent skin Skin moisture evaporates once again, strengthens its moistening effect;Biological carbohydrate gum -1 can by competitively suppress macrophage move suppress because Son promotes the inertia macrophage a little remove to be contaminted, and can slow down the generation of inflammation and reach reduction allergic reaction.Hydroxy decyl Ubiquinone is a kind of Co-Q10, the effect with significant anti-oxidant and anti-aging, and on the one hand it can go deep into cell, reinforcing Consolidation binding ability between cell metabolism function, Polygonum Multiflorum Thunb Extract, on the other hand can in the network structure of epidermis shape glue elasticity, Repairing and then reaches real moisture-keeping efficacy because of the wrinkle caused by fluid loss characteristics.
The peony extract mainly contains flavone compound and polysaccharide dielectric object, energy blood-nourishing and liver, scattered strongly fragrant dissolving stasis, Produce house:Xi'an Ao Ruite bio tech ltd.
Above-mentioned emollient is made up of by weight following components:Propane diols 2~6, Butyrospermum parkii fruit fat 2~6, saualane 2 ~6, isohexadecane 5~8, ring five dimethyl silicone polymer 2~6, dimethyl silicone polymer 0.3~1.2, cetostearyl alcohol 1~ 3。
Preferably, emollient is made up of by weight following components:Propane diols 3~5, Butyrospermum parkii fruit fat 3~5, spiny dogfish Alkane 3~5, isohexadecane 6~7, ring five dimethyl silicone polymer 3~5, dimethyl silicone polymer 0.5~1, cetostearyl alcohol 1.5 ~2.5.
In component, the thickener is at least one of xanthans, hydroxyethyl cellulose, SIMULGELTMNS thickeners.
The present invention is further explained by the following examples.
The whitening spot-removing creams of embodiment 1~5
The whitening spot-removing creams of the embodiment of the present invention 1~5, are made by the formula of table 1.
The whitening spot-removing creams of 1 embodiment of table 1~5 are formulated
The preparation method of the whitening spot-removing creams of embodiment 1~5
By the formula of embodiment 1~5, whitening spot-removing creams are prepared according to the following steps:
(1) by glabridin, 4- butyl resorcinols, disperseed with butanediol and dissolved, it is stand-by;
(2) water is mutually expected to be heated to 75~85 DEG C, stirring and dissolving in the water phase pot of emulsifying pot;The water mutually expects to include Deionized water, propane diols, xanthans, hydroxyethyl cellulose, Sodium Hyaluronate, dipotassium glycyrrhizinate;
(3) oil phase material is heated to 75~85 DEG C, stirring fusing in emulsifying pot;The oil phase material includes: MONTANOVTM68 emulsifying agents, SIMUSOLTM165 emulsifying agents, Butyrospermum parkii fruit fat, saualane, isohexadecane, the poly- diformazan of ring five Radical siloxane, dimethyl silicone polymer, cetostearyl alcohol, tocopherol, ethylhexyl methoxy cinnamate, parahydroxyacet-ophenone;
(4) after dissolving completely, SIMULGELTMNS thickeners are added, is stirred 3~5 minutes, be well mixed;
(5) under stirring, by step (2) gained liquid addition water phase, vacuum homogeneous 3~5 minutes is spaced 5~10 minutes, Homogeneous 3~5 minutes, are then slowly stirred and are cooled to 50~45 DEG C again;
(6) step (1) resulting solution is added to be extracted with biological carbohydrate gum -1, hydroxy decyl ubiquinone, 1,2- hexylene glycols, peony Thing;
(7) stir, discharge.
Test example 1, fairness and humidity measurement
Test object:Skin face is dark yellow, pigment deposition is more apparent, dry trial volunteer, is divided into 6 groups, every group 10 Position subject;Using preceding, every group of face's humidity and fairness of subject are without significant difference.
Application method:Every group with whitening spot-removing creams obtained in embodiment 1~5, (Lancome is attained with commercially available external product respectively Bloom), face is applied to after washing one's face sooner or later daily, it is continuous to use 2 months.
Method of testing:After washing one's face, any cosmetic product is not applied, using the water-white detector of intelligence, (beautiful the standing in Shenzhen knows that science and technology has Limit company), read the fairness and humidity of skin.
2 every groups of subjects of table use face's fairness and humidity (average value) before and after creams
As shown in table 2, the creams whitening effect of embodiment 3 is optimal, is significantly better than commercially available prod, the breast of embodiment 2 for result White moistening effect is optimal, is significantly better than commercially available prod;And observe:Front and rear face is used using the subject of embodiment 1~3 Pigmentation is obviously improved, using the subject of embodiment 4~5 and commercially available prod before and after face pigmentation improve compared with It is small.Therefore, creams of the invention have excellent whitening, nti-freckle, moistening effect, it is adaptable to which skin face is dark yellow, pigment deposition It is more apparent, dry the skin repair of crowd;Simultaneously as creams formula is without essence, without mineral oil, without Ni Bo Golden esters preservative, it is without any side effects, it is equally applicable to need all groups of daily skin care.
The above is only used to the convenient explanation present invention, in the scope for not departing from present invention creation, is familiar with this skill What those skilled in the art of art was done various simple in a disguised form should belong to protection scope of the present invention with modification.

Claims (7)

1. a kind of whitening spot-removing creams, composed of the following components:Ethylhexyl methoxy cinnamate, 4- butyl resorcinol, light Licoricidin, hydroxy decyl ubiquinone, Sodium Hyaluronate, biological carbohydrate gum -1, tocopherol, dipotassium glycyrrhizinate, peony extract, to hydroxyl Acetophenone, 1,2- hexylene glycols, emollient, thickener, emulsifying agent, water, butanediol.
2. a kind of whitening spot-removing creams according to claim 1, it is characterised in that:It is made up of by weight following components: 2~10 parts of ethylhexyl methoxy cinnamate, 0.1~1 part of 4- butyl resorcinol, 0.001~0.01 part of glabridin, the hydroxyl last of the ten Heavenly stems 0.2~2 part of base ubiquinone, 0.03~0.3 part of Sodium Hyaluronate, biological 0.3~4 part of carbohydrate gum -1,0.2~2 part of tocopherol, Radix Glycyrrhizae 0.03~0.3 part of sour dipotassium, 2~15 parts of peony extract, 0.1~0.6 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.05~ 0.5th, 15~35 parts of emollient, 0.5~3 part of thickener, 1~8 part of emulsifying agent, 30~65 parts of water, 1~8 part of butanediol.
3. a kind of whitening spot-removing creams according to claim 1, it is characterised in that:It is made up of by weight following components: 3~7 parts of ethylhexyl methoxy cinnamate, 0.2~0.6 part of 4- butyl resorcinol, 0.002~0.006 part of glabridin, hydroxyl 0.3~1.8 part of decyl ubiquinone, 0.05~0.25 part of Sodium Hyaluronate, biological 0.5~3.5 part of carbohydrate gum -1, tocopherol 0.3~ 1.8 parts, 0.05~0.25 part of dipotassium glycyrrhizinate, 3~12 parts of peony extract, 0.2~0.5 part of parahydroxyacet-ophenone, 1,2- Hexylene glycol 0.1~0.5,20~30 parts of emollient, 1~2.5 part of thickener, 2~6 parts of emulsifying agent, 35~60 parts of water, butanediol 2 ~6 parts.
4. a kind of whitening spot-removing creams according to claim 1, it is characterised in that:It is made up of by weight following components: 4~6 parts of ethylhexyl methoxy cinnamate, 0.3~0.5 part of 4- butyl resorcinol, 0.003~0.005 part of glabridin, hydroxyl 0.5~1.5 part of decyl ubiquinone, 0.1~0.2 part of Sodium Hyaluronate, biological 1~3 part of carbohydrate gum -1,0.5~1.5 part of tocopherol, 0.1~0.2 part of dipotassium glycyrrhizinate, 5~10 parts of peony extract, 0.3~0.4 part of parahydroxyacet-ophenone, 1,2- hexylene glycols 0.2 ~0.4,22.5~28.5 parts of emollient, 1.5~2.25 parts of thickener, 3~5 parts of emulsifying agent, 40~55 parts of water, butanediol 3~5 Part.
5. a kind of whitening spot-removing creams according to any one of Claims 1 to 4, it is characterised in that:The emollient by with Lower component is by weight composition:Propane diols 2~6, Butyrospermum parkii fruit fat 2~6, saualane 2~6, isohexadecane 5~8, ring five gather Dimethyl siloxane 2~6, dimethyl silicone polymer 0.3~1.2, cetostearyl alcohol 1~3.
6. a kind of whitening spot-removing creams according to claim 5, it is characterised in that:The emollient is by following components by weight Amount is than composition:Propane diols 3~5, Butyrospermum parkii fruit fat 3~5, saualane 3~5, isohexadecane 6~7, the polydimethylsiloxanes of ring five Alkane 3~5, dimethyl silicone polymer 0.5~1, cetostearyl alcohol 1.5~2.5.
7. a kind of whitening spot-removing creams according to any one of Claims 1 to 4, it is characterised in that:The thickener is Huang At least one of virgin rubber, hydroxyethyl cellulose, SIMULGEL NS thickeners.
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CN107296764A (en) * 2017-06-28 2017-10-27 深圳市永济泰科技有限公司 Cream and preparation method thereof
CN108096096A (en) * 2017-12-27 2018-06-01 珠海伊斯佳科技股份有限公司 A kind of composition for having both long-acting moisturizing and whitening function
CN108324589A (en) * 2018-05-11 2018-07-27 广东省中药研究所 A kind of composition for whitening skin and preparation method thereof
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CN113679629A (en) * 2021-08-31 2021-11-23 珀莱雅化妆品股份有限公司 Whitening composition for cosmetics and preparation method thereof
CN114504524A (en) * 2022-01-19 2022-05-17 珀莱雅化妆品股份有限公司 Nanoparticle emulsion with whitening and anti-aging effects and preparation method thereof

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CN107296764B (en) * 2017-06-28 2020-06-26 深圳市永济泰科技有限公司 Cream and preparation method thereof
CN107296764A (en) * 2017-06-28 2017-10-27 深圳市永济泰科技有限公司 Cream and preparation method thereof
CN108096096A (en) * 2017-12-27 2018-06-01 珠海伊斯佳科技股份有限公司 A kind of composition for having both long-acting moisturizing and whitening function
CN108324589A (en) * 2018-05-11 2018-07-27 广东省中药研究所 A kind of composition for whitening skin and preparation method thereof
CN108420749A (en) * 2018-05-11 2018-08-21 广东省中药研究所 A kind of skin care item and preparation method thereof with anti-aging effects
CN110200874A (en) * 2019-07-08 2019-09-06 卢琛 A kind of whitening and spot eliminating cream and preparation method thereof
CN110327247A (en) * 2019-08-15 2019-10-15 广州栢汇生物科技有限公司 Whitening and spot eliminating cream
CN110538107A (en) * 2019-09-16 2019-12-06 安婕妤化妆品科技股份有限公司 cosmetic containing vitamin components
CN110960478A (en) * 2019-12-04 2020-04-07 广州博科健康科技集团有限公司 Freckle-removing cream containing umbilical cord extract and preparation method thereof
CN113318030A (en) * 2021-06-18 2021-08-31 广州恒芳生物科技有限公司 Whitening and freckle removing cream and preparation method thereof
CN113318030B (en) * 2021-06-18 2021-12-03 广州恒芳生物科技有限公司 Whitening and freckle removing cream and preparation method thereof
CN113679629A (en) * 2021-08-31 2021-11-23 珀莱雅化妆品股份有限公司 Whitening composition for cosmetics and preparation method thereof
CN114504524A (en) * 2022-01-19 2022-05-17 珀莱雅化妆品股份有限公司 Nanoparticle emulsion with whitening and anti-aging effects and preparation method thereof
CN114504524B (en) * 2022-01-19 2024-01-26 珀莱雅化妆品股份有限公司 Nanoparticle emulsion with whitening and anti-aging effects and preparation method thereof

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