CN106727245A - A kind of heat-clearing moisturizing lip-stick and preparation method thereof - Google Patents
A kind of heat-clearing moisturizing lip-stick and preparation method thereof Download PDFInfo
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- CN106727245A CN106727245A CN201710050455.8A CN201710050455A CN106727245A CN 106727245 A CN106727245 A CN 106727245A CN 201710050455 A CN201710050455 A CN 201710050455A CN 106727245 A CN106727245 A CN 106727245A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/001—Preparations for care of the lips
Abstract
The invention discloses a kind of heat-clearing moisturizing lip-stick and preparation method thereof, the lip-stick includes the raw material components of following weight portion：30~50 parts of the seed of Job's tears, 10~30 parts of lily, 5~15 parts of Poria cocos, 5~10 parts of green cucumber, 30~50 parts of coconut oil, 5~10 parts of honey.The sufficiently effective effective component extracting of preparation method so that many raw material components are shared, has functions that clearing heat and detoxicating, cooling and activating blood, profit lip, and edible, and human body thing side effect is acted on, and is commonly used, and can prevent the chronic disease repeatedly such as bleb, the effect of bright lip.
Description
Technical field
The present invention relates to lipstick technical field, more particularly to a kind of heat-clearing moisturizing lip-stick and preparation method thereof.
Background technology
In dry season, due to air pollution and the reason of environment, human body lip tendency is increasingly dried, and is easily triggered
Various lips diseases, such as lip are peeled, and are a lack of vitamin；Lip color is excessively red, and possible " excessive internal heat ", red represents in the traditional Chinese medical science
Heat symptom-complex, hoards excessive heat in vivo, careful to get angry；Lip bubbles, it may be possible to herpes labialis, is grown in lip or the small water around it
Bubble, infectiousness is high, the multiple resistance downward period such as with flu, fever, and can propagate, although herpes labialis is within these few days
Can disappear, but flavour is very bad receives；It is mostly to add the raw materials such as pigment, preservative in existing moisturizing lip-stick, particularly exists
During using raw material containing unsaturated compounds such as aldehyde, ketone, easily cause allergy, easily cause allergic and stimulate, lip cannot
Effective moisturizing moisture evaporation is accelerated, and becomes water shortage, dry and cracked, obscure and growth line trace, and when using lipstick, just inevitably
Enter into the stomach of people, accumulate over a long period, also can be to the body of people according into certain injury.Therefore the shield of natural herb is needed to have
Lipstick, in the case of without preservative, colour component, solves problem above so that the treatment of lip is significantly imitated
Really.
The content of the invention
In view of this, the invention provides a kind of heat-clearing moisturizing lip-stick, solve lip-stick be unable to it is fiery, moist under heat-clearing
The problem of moisturizing.
The technological means that the present invention is used is as follows：A kind of heat-clearing moisturizing lip-stick, including following weight portion raw material components：
30~50 parts of the seed of Job's tears, 10~30 parts of lily, 5~15 parts of Poria cocos, 5~10 parts of green cucumber, 30~50 parts of coconut oil, 5~10 parts of honey.
Preferably, including following weight part ratio component：40 parts of the seed of Job's tears, 22 parts of lily, 10 parts of Poria cocos, 7 parts of green cucumber, coconut oil
35 parts, 5 parts of honey.
Present invention additionally comprises a kind of preparation method of heat-clearing moisturizing lip-stick, comprise the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos 1~2h of raw material soaking, crushing is dried, with dense
The ethanol water spent for 50%~70% is extracted, and obtains leaching liquor, and solvent is evaporated to leaching liquor, 0.08~
Concentration is heated under the conditions of 0.1Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH is adjusted
Value, carries out 1~2h of insulation in water-bath, is centrifuged after the enzyme that goes out, and takes supernatant liquor and is concentrated；
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, is entered
Row supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, obtain mixed liquor, adjust pH value, then by coconut oil
Divide equally 2~3 parts with honey and incorporate mixed liquor, stir, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 100~120 DEG C after, be cooled to 50~70
℃；
(6) form, the demoulding.
Preferably, extraction temperature is 60~80 DEG C in the step (1), and extraction time is 2~3h, and extracting times are 2~3
It is secondary.
Preferably, concentrated with Rotary Evaporators in the step (2), obtained the second concentrate.
Preferably, after adding pectase in the step (2), enzymolysis processing, 40 DEG C~55 DEG C of hydrolysis temperature, enzymolysis are carried out
Time 1h~2h.
Preferably, slurry and the weight ratio of pectase are 3 in the step (2):1~5:1.
Preferably, regulation pH value is 3~5 in the step (2)
Preferably, cold pressing temperature is 40~60 DEG C in the step (3).
Preferably, pH value is 4.5~7 in the step (4).
Using a kind of heat-clearing moisturizing lip-stick provided by the present invention, with following benefit：The lip-stick mainly nourishes mouth
Lip, fire under heat-clearing prevents various lips diseases, and with edibility, it is non-toxic to human body.Wherein the seed of Job's tears is because containing various dimensions
Raw element and mineral matter, enhance metabolism, and vitamin E, the vitamin B contained in the seed of Job's tears can improve lip color, tool
There is fire under moisturizing；Coconut oil is obtained by natural squeezing, has ensured the effect without side effect, and with other raw material components
Melting is notable.The abundant extraction that the preparation method passes through the first concentrate and the second concentrate, by extracts active ingredients out, group
Divide collocation reasonable, determined curative effect, effect stabilization is persistently.
Seed of Job's tears pharmacological action：The seed of Job's tears is sweet, light, cold nature, returns spleen, stomach, lung channel；There are invigorating spleen for diuresis, dampness removing eliminating impediment, heat-clearing
The effect of apocenosis, eliminating dampness and heat；Can be used to treat the diseases such as oedema, tinea pedis, acute appendicitis.The seed of Job's tears is because containing multivitamin and mineral
Matter, enhances metabolism and reduces stomach and intestine burden；It is also effective to diseases such as chronic enteritis, indigestions；Seed of Job's tears energy
Enhancing renal function, and there is reducing fever and causing diuresis to act on；The seed of Job's tears plays the role of anti-cancer, can effectively suppress the propagation of cancer cell；Can be with skin
Gloss is fine and smooth, eliminates acne, color spot, improves the colour of skin, and it has certain treatment for infecting wart for causing etc. by virus
Effect.
Lily pharmacological action：Moisten the lung and relieve the cough, lily fresh goods contains lymphatic temperament, with moistening for dryness and clearing away heat effect, in medical treatment
The disease such as the dryness of the lung or cough with lung heat can often be proved effective.Antitoxic heart-soothing and sedative, lily enters the heart channel of Hang-Shaoyin, and cold nature can relieving restlessness that clears away heart-fire, antitoxic heart-soothing and sedative, use
Do not disappear in waste heat after pyreticosis, lost in a reverie, insomnia and dreamful sleep, feel depressed, the illness such as susceptible to sorrow and being about to weep.Beautifying face and moistering lotion, lily is clean
Bai Jiaoyan, fresh goods is rich in lymphatic temperament and vitamin, and, often to eat lily beneficial to skin cell metabolism has certain beautification function.
Cancer-resisting, lily contains various alkaloids, there is prevention effect, energy hemocytes increasing, to chemotherapy and radiation to leukopenia
Property treatment after cytopenia have therapeutic action.Lily can also promote and strengthen monocyte system and phagocytic function in vivo,
The humoral immunity ability of body is improved, therefore lily has preferable preventing iron-smelting effect to kinds cancer, this product is sweet cool clear and rich, and master enters
The lung heart, is longer than clearing away the lungheat and moisturizing cough-relieving, clearing away the heart fire and tranquillizing arresting convulsion, by xeropulmonary cough, dysphoria are uneasy conventional.
Poria cocos pharmacological action：Nature and flavor, it is mild-natured, it is sweet, light.Clearing damp and promoting diuresis, invigorating the spleen calming heart.To staphylococcus aureus, greatly
Enterobacteria, proteus etc. have inhibitory action, and Poria cocos has direct relexation to family's rabbits infestines, to rat pylorus ligation
The ulcer for being formed has preventive effect, and can drop hydrochloric acid in gastric juice.Separately there is significant protective effect to Liver Damage in Rats caused by CCl4, make paddy
Pyruvic transaminase activity is substantially reduced, and prevents necrosis of liver cells.
Green cucumber pharmacological action：Cucumber is sweet, cool in nature, bitter, nontoxic, enters spleen, stomach, large intestine channel；Clearing away heat and promoting diuresis, removing toxicity for detumescence,
Promote the production of body fluid to quench thirst.Cure mainly the illnesss such as the hot polydipsia of body, abscess of throat, wind-heat eye illness, jaundice with damp-heat pathogen, difficult urination.It is antitumor:In cucumber
The cucurbitacin C for containing has the effect for improving immune function of human body, reaches antitumor purpose.Anti-aging:Containing abundant in cucumber
Vitamin E, can play and promote longevity, the effect of anti-aging；Cucumber chitinase in cucumber, there is very strong bioactivity, can be effective
Ground promotes the metabolism of body.Juice is smash with cucumber and embrocate skin, there is moisturizing, unfold wrinkle effect.Invigorating brain and relieving mental uneasiness:Cucumber contains
Vitamin B1, it is favourable to improving brain and nervous function, can tranquilizing the mind, auxiliary treatment of insomnia disease.
Coconut oil pharmacological action：Driving away summer heat gas.Control mange, pernio.Treat tooth disease, pernio.Put neurodermatitis on the skin.
Honey pharmacological action：Honey is sweet, mild-natured, enters lung, spleen, large intestine channel；There is bowl spares to moisturize, relieve pain, effect of removing toxic substances；
For physically weak, xeropulmonary cough, dry constipation of intestines, gastral cavity pain, nasosinusitis, aphtha, the burning hot wound of soup.The composition of blood can be improved, promoted
Heart and brain and vascular function；Honey has protective effect to liver；Honey can regain one's strength of body rapidly, dispelling fatigue, strengthen to disease
Resistance；Honey also has the effect of sterilization, often eats honey, not only without prejudice to tooth, moreover it is possible to sterilization is played in oral cavity
The effect of sterilization；Honey can treat the skin damage of moderate, particularly scald, when honey is regarded into skin wound dressing, bacterium
Cannot grow；Honey can also relax bowel (as long as the real honey of mature native has the effect for relaxing bowel).
Specific embodiment
Principle of the invention and feature are described below, example is served only for explaining the present invention, is not intended to limit
Determine the scope of the present invention.
Embodiment 1
A kind of heat-clearing moisturizing lip-stick, including following raw material components：Seed of Job's tears 30g, lily 10g, Poria cocos 5g, green cucumber 5g,
Coconut oil 30g, honey 5g.
A kind of preparation method of heat-clearing moisturizing lip-stick, comprises the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos 1~2h of raw material soaking, crushing is dried, with dense
The ethanol water spent for 50% is extracted, and extraction temperature is 60 DEG C, and extraction time is 2h, and extracting times are 2 times, must be extracted
Liquid, solvent is evaporated to leaching liquor, and concentration is heated under the conditions of 0.08Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH value is adjusted
3, carry out enzymolysis processing, 40 DEG C of hydrolysis temperature, enzymolysis time 1h carries out insulation 1h in water-bath, is centrifuged after the enzyme that goes out, and takes upper strata
Clear liquid is concentrated with Rotary Evaporators；Slurry is 3 with the weight ratio of pectase:1.
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, it is low
Warm pressing temperature is 40 DEG C, carries out supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, mixed liquor is obtained, adjusts pH value, pH value is 4.5,
Coconut oil and honey are divided equally 2 parts again and incorporates mixed liquor, stirred, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 100 DEG C after, be cooled to 50 DEG C；
(6) form, the demoulding.
Embodiment 2
A kind of heat-clearing moisturizing lip-stick, including following raw material components：Seed of Job's tears 50g, lily 30g, Poria cocos 15g, green cucumber
10g, coconut oil 50g, honey 10g.
A kind of preparation method of heat-clearing moisturizing lip-stick, comprises the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos raw material soaking 2h, crushing is dried, is with concentration
70% ethanol water is extracted, and extraction temperature is 80 DEG C, and extraction time is 3h, and extracting times are 3 times, obtain leaching liquor,
Solvent is evaporated to leaching liquor, concentration is heated under the conditions of 0.1Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH value is adjusted
5, carry out enzymolysis processing, 55 DEG C of hydrolysis temperature, enzymolysis time 2h carries out insulation 2h in water-bath, is centrifuged after the enzyme that goes out, and takes upper strata
Clear liquid is concentrated with Rotary Evaporators；Slurry is 5 with the weight ratio of pectase:1.
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, it is low
Warm pressing temperature is 60 DEG C, carries out supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, mixed liquor is obtained, adjusts pH value, pH value is 7, then
Coconut oil and honey are divided equally 3 parts and incorporates mixed liquor, stirred, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 120 DEG C after, be cooled to 70 DEG C；
(6) form, the demoulding.
Embodiment 3
A kind of heat-clearing moisturizing lip-stick, including following weight portion raw material components：Seed of Job's tears 35g, lily 20g, Poria cocos 10g,
Green cucumber 7g, coconut oil 40g, honey 6g.
A kind of preparation method of heat-clearing moisturizing lip-stick, comprises the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos raw material soaking 2h, crushing is dried, is with concentration
60% ethanol water is extracted, and extraction temperature is 70 DEG C, and extraction time is 3h, and extracting times are 3 times, obtain leaching liquor,
Solvent is evaporated to leaching liquor, concentration is heated under the conditions of 0.09Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH is adjusted
Value, carries out enzymolysis processing, 45 DEG C of hydrolysis temperature, and enzymolysis time 2h carries out insulation 2h in water-bath, is centrifuged after the enzyme that goes out, and takes upper strata
Clear liquid is concentrated with Rotary Evaporators；Slurry is 4 with the weight ratio of pectase:1.
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, it is low
Warm pressing temperature is 50 DEG C, carries out supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, mixed liquor is obtained, adjusts pH value, pH value is 6, then
Coconut oil and honey are divided equally 3 parts and incorporates mixed liquor, stirred, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 110 DEG C after, be cooled to 60 DEG C；
(6) form, the demoulding.
Embodiment 4
A kind of heat-clearing moisturizing lip-stick, including following weight portion raw material components：Seed of Job's tears 45g, lily 22g, Poria cocos 12g,
Green cucumber 8g, coconut oil 45g, honey 8g.
A kind of preparation method of heat-clearing moisturizing lip-stick, comprises the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos raw material soaking 2h, crushing is dried, is with concentration
70% ethanol water is extracted, and extraction temperature is 70 DEG C, and extraction time is 3h, and extracting times are 2 times, obtain leaching liquor,
Solvent is evaporated to leaching liquor, concentration is heated under the conditions of 0.08Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH is adjusted
Value, carries out enzymolysis processing, 50 DEG C of hydrolysis temperature, and enzymolysis time 2h carries out insulation 1h in water-bath, is centrifuged after the enzyme that goes out, and takes upper strata
Clear liquid is concentrated with Rotary Evaporators；Slurry is 5 with the weight ratio of pectase:1.
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, it is low
Warm pressing temperature is 60 DEG C, carries out supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, mixed liquor is obtained, adjusts pH value, pH value is 6, then
Coconut oil and honey are divided equally 3 parts and incorporates mixed liquor, stirred, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 120 DEG C after, be cooled to 60 DEG C；
(6) form, the demoulding.
Embodiment 5
A kind of heat-clearing moisturizing lip-stick, including following weight portion raw material components：40 parts of the seed of Job's tears, 22 parts of lily, Poria cocos 10
Part, 7 parts of green cucumber, 35 parts of coconut oil, 5 parts of honey.
A kind of preparation method of heat-clearing moisturizing lip-stick, comprises the following steps：
The preparation of (1) first concentrate：By the seed of Job's tears, lily, Poria cocos and raw material soaking 2h, crushing is dried, uses concentration
Ethanol water for 65% is extracted, and extraction temperature is 70 DEG C, and extraction time is 3h, and extracting times are 3 times, must be extracted
Liquid, solvent is evaporated to leaching liquor, and concentration is heated under the conditions of 0.081Mpa；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH is adjusted
Value, carries out enzymolysis processing, 55 DEG C of hydrolysis temperature, and enzymolysis time 2h carries out insulation 2h in water-bath, is centrifuged after the enzyme that goes out, and takes upper strata
Clear liquid is concentrated with Rotary Evaporators；Slurry is 4 with the weight ratio of pectase:1.
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, it is low
Warm pressing temperature is 55 DEG C, carries out supercritical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, mixed liquor is obtained, adjusts pH value, pH value is 6, then
Coconut oil and honey are divided equally 3 parts and incorporates mixed liquor, stirred, obtain lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 110 DEG C after, be cooled to 60 DEG C；
(6) form, the demoulding.
In order to verify beneficial effects of the present invention, following experiment has been done：
First, 1, materials and methods
1.1 trial drugs：Lotion prepared by melting embodiment 5.
1.2 experimental animals：From experiment mice, 20~30g of body weight.
1.3 acute toxicity tests：Take 50 mouse and be randomly divided into 2 groups, every group 25, test group：It is to melt by trial drug
Melt medicine gastric infusion, blank group is normally ingested, drinks water to provide.Uniform intervals are administered 3 times in 1d, and dosage is containing total medicine
Amount 30%, is administered 14 days, and observes the situation of mouse, and survival condition, mouse poisoning symptom puts to death mouse, and carry out after 14 days
Pathologic examination.
1.4 cumulative toxicity tests：Take 80 mouse and be randomly divided into 4 groups, every group 20 is only raised, and embodiment 5 is melted
Medicine be divided into small dose group (total content of dispersion 10%), middle dose group (total content of dispersion 40%), high dose group (total content of dispersion
70%) gavage amount is carried out with blank group (normal water).Observation mouse ordinary circumstance, after being administered 1 month, extracting mouse carries out the heart
Dirty blood sampling checks physiochemical indice and blood biochemical analysis index.Experiment takes important organ after terminating, and claims its weight in wet base, calculates internal organs system
Number.
2nd, result
2.1 acute toxicity tests：
| Group | Medicine | Number of mice (only) | Death toll (only) | The death rate (%) |
| Test group | Melting lip-stick | 25 | 0 | 0 |
| Blank group | Water | 25 | 0 | 0 |
2.2 cumulative toxicity tests：
| Group | Medicine | Number of mice (only) | Death toll (only) | The death rate (%) |
| Small dose group | Total content of dispersion 10% | 20 | 0 | 0 |
| Middle dose group | Total content of dispersion 40% | 20 | 0 | 0 |
| High dose group | Total content of dispersion 70% | 20 | 0 | 0 |
| Blank group | Water | 20 | 0 | 0 |
The organ coefficient of each mouse in cumulative toxicity test
3rd, discuss
Mouse in acute toxicity test in test group and blank group is showed no death toll, shows that lip-stick of the present invention does not contain
Toxic composition, does not injure to human body.
Mouse in cumulative toxicity test in test combinations blank group also has no death toll, shows that lip-stick of the present invention does not contain
Toxic composition, does not injure to human body, and the organ coefficient index (P not notable with blank group difference in each test group>
0.05)。
The 2nd, control group is set
Control group 1：The control group is to contain the seed of Job's tears with the difference of embodiment 5.Its preparation method and the phase of embodiment 5
Together.
Control group 2：The control group is not contain the seed of Job's tears, lily, coconut oil with the difference of embodiment 5.Its preparation method
It is same as Example 5.
Control group 3：The control group is directly to be concentrated raw material components with the preparation method difference of embodiment 5：Will
The seed of Job's tears, lily and Poria cocos raw material soaking 2h, are dried crushing, are extracted with the ethanol water that concentration is 65%, extraction
Temperature is 70 DEG C, and extraction time is 3h, and extracting times are 3 times, obtain leaching liquor, and solvent is evaporated to leaching liquor,
Concentration is heated under the conditions of 0.081Mpa.
Control group 4：The control group is directly to be concentrated raw material components with the preparation method difference of embodiment 5：Will
The seed of Job's tears, lily and Poria cocos raw material add water crushing and beating, obtain slurry；Pectase is added, pH value is adjusted, enzymolysis processing is carried out, digested
55 DEG C of temperature, enzymolysis time 2h carries out insulation 2h in water-bath, is centrifuged after the enzyme that goes out, and take supernatant liquor is carried out with Rotary Evaporators
Concentration；Slurry is 4 with the weight ratio of pectase:1.
Performance of keeping humidity test experiments：
Using lip as test position during test, lip-stick is smeared, in 25 DEG C, the indoor environment of relative humidity 50%,
The moisture content of lip is carried out on female consumer lip with moisture of skin measuring instrument to every group of 20 ages between 18~50 years old
Content measuring, its result is represented by the humidity measurements (H) for setting, to evaluate the replenishing water and preserving moisture performance of the product.
Wherein：Lip humidity H values before H1-smearing lip-stick, the lip humidity after H2-smearing lip-stick in 10 minutes
H values, lip humidity H3 values after H3-smearing lip-stick 1 hour.Make-up water percentage=H2/H1 × 100%, moisturizing rate=H3/H2 ×
100%.
Its performance of keeping humidity test table is as shown in table 1 below：
| Group | H1 | H2 | H3 | Make-up water percentage (%) | Moisturizing rate (%) |
| Embodiment 1 | 35.6 | 66.1 | 62.6 | 184 | 94.7 |
| Embodiment 2 | 35.6 | 66.6 | 63.4 | 183 | 95.2 |
| Embodiment 3 | 35.6 | 67.2 | 63.1 | 183 | 93.9 |
| Embodiment 4 | 35.6 | 66.8 | 63.3 | 185 | 94.8 |
| Embodiment 5 | 35.6 | 68.5 | 65.7 | 192 | 96.0 |
| Control group 1 | 35.6 | 60.5 | 45.8 | 170 | 75.7 |
| Control group 2 | 35.6 | 58.2 | 43.4 | 163 | 74.6 |
| Control group 3 | 35.6 | 62.3 | 50.6 | 175 | 81.2 |
| Control group 4 | 35.6 | 62.8 | 52.4 | 176 | 83.4 |
From the test data of table 1, compared with control group, the present invention has good heat-clearing moisturizing lip-stick of the invention
Moisturizing performance and performance of keeping humidity.Control group 1 is compared with Example 5 compared with the seed of Job's tears has multivitamin and mineral matter, the present invention
The vitamin in the seed of Job's tears is extracted by corresponding preparation method, kidney splenic function can be strengthened, had to edema certain
Curative effect, and lip color can be improved, it is the raw material of help；Collocation lily, the raw material of coconut oil so that the lip-stick has good
Effect；Its preparation method uses different extracting methods according to the heterogeneity selection of raw material, sufficiently extracts active principle
Out so that lip-stick has the effect of heat-clearing moisturizing.
Fiery performance test experiment under heat-clearing：
Patient 20 of the selection with lip herpe simplex, random point 2 groups, every group 10, experimental group is to smear embodiment 5
The lip-stick of making, control group smears commercially available certain brand has the anti-drying lip-stick of moisturizing, and experimental period is 3 days, its experiment
Result is as shown in table 2 below：
As shown in Table 2, lip-stick of the present invention has significant curative effect achievement in treatment herpe simplex, is selected compared with control group
Lip-stick it is evident in efficacy.
Support temperament energy test experiments：
Occur that black circle, lip color be too red, too deep, excessively light white or skin of lip is chapped around lip etc. and have with
The health status of spleen has certain relation.With five kinds of lipsticks of the embodiment of the present invention as experimental group, commercially available certain brand lipstick for control
Group, to lip color, too red patient tests.Method of testing is：30 patients are divided into 6 groups, every morning, sleep before
Smear once, every two days using effects to tester are observed and recorded, as a result as shown in table 3 below：
| Group | Time (2 days) | Time (5 days) |
| Embodiment 1 | Lip discoloration is shallow | It is almost recovered |
| Embodiment 2 | Lip color is soft and moist | Recovery from illness |
| Embodiment 3 | Lip color is soft and moist | It is almost recovered |
| Embodiment 4 | Lip discoloration is shallow | Recovery from illness |
| Embodiment 5 | Lip color is soft and moist | Recovery from illness (gain color) |
| Control group | It is constant | It is slight to take a turn for the better |
As seen from the results in Table 3, control group advanced symptoms are basically unchanged, and there is slight improvement in the later stage, it may be possible to patient's itself
Adjustment effect, and the lipstick of experimental group use begins with significant improvement two days later, has been fully recovered substantially after the 5th day,
Illustrating that lip-stick of the present invention has improves lip color health so that lip discoloration obtains soft and moist.
In sum, using a kind of heat-clearing moisturizing lip-stick provided by the present invention and preparation method thereof, lip-stick master
Lip is nourished, fire under heat-clearing prevents various lips diseases, and with edibility, it is non-toxic to human body.Wherein the seed of Job's tears is because containing
There are multivitamin and mineral matter, enhance metabolism, vitamin E, the vitamin B contained in the seed of Job's tears, Ke Yigai
Kind lip color, has functions that fire under moisturizing；Lily have it is sweet cool clear and rich, it is main enter the lung heart, with moistening for dryness and clearing away heat effect；Coconut oil leads to
Cross natural squeezing and obtain, ensure the effect without side effect, and it is notable with the melting of other raw material components.The preparation method is by the
The abundant extraction of one concentrate and the second concentrate, by extracts active ingredients out, component collocation is reasonable, determined curative effect, effect
Stabilization is lasting.
Presently preferred embodiments of the present invention is the foregoing is only, is not intended to limit the invention, it is all in essence of the invention
Within god and principle, any modification, equivalent substitution and improvements done etc. should be included within the scope of protection of the invention.
Claims (10)
1. a kind of heat-clearing moisturizing lip-stick, it is characterised in that the raw material components including following weight portion：30~50 parts of the seed of Job's tears, hundred
10~30 parts of conjunction, 5~15 parts of Poria cocos, 5~10 parts of green cucumber, 30~50 parts of coconut oil, 5~10 parts of honey.
2. a kind of heat-clearing moisturizing lip-stick according to claim 1, it is characterised in that including following weight part ratio component：
40 parts of the seed of Job's tears, 22 parts of lily, 10 parts of Poria cocos, 7 parts of green cucumber, 35 parts of coconut oil, 5 parts of honey.
3. the preparation method of a kind of heat-clearing moisturizing lip-stick according to claim 1, it is characterised in that including following step
Suddenly：
The preparation of (1) first concentrate：By the seed of Job's tears, lily and Poria cocos 1~2h of raw material soaking, crushing is dried, is with concentration
50%~70% ethanol water is extracted, and obtains leaching liquor, and solvent is evaporated to leaching liquor, in 0.08~0.1Mpa bars
Concentration is heated under part；
The preparation of (2) second concentrates：Green cucumber raw material is added water crushing and beating, slurry is obtained；Pectase is added, pH value is adjusted,
1~2h of insulation is carried out in water-bath, is centrifuged after the enzyme that goes out, taken supernatant liquor and concentrated；
(3) preparation of coconut oil：The coconut meat of drying is crushed, and after being put into cold pressing expeller and carrying out cold pressing, is surpassed
Critical CO2Extraction, obtains coconut oil.
(4) by the first concentrate and the second concentrate mixing and stirring, obtain mixed liquor, adjust pH value, then by coconut oil and honeybee
Honey divides equally 2~3 parts and incorporates mixed liquor, stirs, and obtains lotion；
(5) sterilized cooling：Will lotion sterilization after be cooled down, sterilization temperature be 100~120 DEG C after, be cooled to 50~70 DEG C；
(6) form, the demoulding.
4. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (1)
Middle extraction temperature is 60~80 DEG C, and extraction time is 2~3h, and extracting times are 2~3 times.
5. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (2)
It is middle to be concentrated with Rotary Evaporators, obtain the second concentrate.
6. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (2)
After middle addition pectase, enzymolysis processing, 40 DEG C~55 DEG C of hydrolysis temperature, enzymolysis time 1h~2h are carried out.
7. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (2)
Middle slurry is 3 with the weight ratio of pectase:1~5:1.
8. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (2)
Middle regulation pH value is 3~5.
9. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (3)
Middle cold pressing temperature is 40~60 DEG C.
10. a kind of preparation method of heat-clearing moisturizing lip-stick according to claim 3, it is characterised in that the step (4)
Middle pH value is 4.5~7.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112616941A (en) * | 2020-12-23 | 2021-04-09 | 曾越 | Health-care coconut oil |
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| KR20090073622A (en) * | 2007-12-31 | 2009-07-03 | 주식회사 코리아나화장품 | Cosmetic composition comprising a rhodochrosite extract, smithsonite extract and phytosteryl derivatives as active ingredient |
| CN102440934A (en) * | 2010-10-13 | 2012-05-09 | 汪强 | Lip care balm capable of effectively preventing inflammation on lips |
| CN103040703A (en) * | 2012-12-18 | 2013-04-17 | 青岛博益特生物材料有限公司 | Honey lip balm |
| CN105581966A (en) * | 2016-02-29 | 2016-05-18 | 广西南岜仔科技有限公司 | Lithospermum erythrorhizon lipstick and preparation method thereof |
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| KR20090073622A (en) * | 2007-12-31 | 2009-07-03 | 주식회사 코리아나화장품 | Cosmetic composition comprising a rhodochrosite extract, smithsonite extract and phytosteryl derivatives as active ingredient |
| CN102440934A (en) * | 2010-10-13 | 2012-05-09 | 汪强 | Lip care balm capable of effectively preventing inflammation on lips |
| CN103040703A (en) * | 2012-12-18 | 2013-04-17 | 青岛博益特生物材料有限公司 | Honey lip balm |
| CN105581966A (en) * | 2016-02-29 | 2016-05-18 | 广西南岜仔科技有限公司 | Lithospermum erythrorhizon lipstick and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112616941A (en) * | 2020-12-23 | 2021-04-09 | 曾越 | Health-care coconut oil |
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