CN106726769A - A kind of peony seed oil anti-apolexis composition and preparation method thereof - Google Patents
A kind of peony seed oil anti-apolexis composition and preparation method thereof Download PDFInfo
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- CN106726769A CN106726769A CN201611229458.XA CN201611229458A CN106726769A CN 106726769 A CN106726769 A CN 106726769A CN 201611229458 A CN201611229458 A CN 201611229458A CN 106726769 A CN106726769 A CN 106726769A
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- seed oil
- aging cosmetics
- composition according
- alcohol
- cosmetics composition
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- 239000000203 mixture Substances 0.000 title claims abstract description 49
- 235000015112 vegetable and seed oil Nutrition 0.000 title claims abstract description 20
- 235000006484 Paeonia officinalis Nutrition 0.000 title claims abstract description 17
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 241000736199 Paeonia Species 0.000 title abstract description 17
- 239000002537 cosmetic Substances 0.000 claims abstract description 33
- 230000003712 anti-aging effect Effects 0.000 claims abstract description 22
- 239000002994 raw material Substances 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 10
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 claims description 8
- 229920005573 silicon-containing polymer Polymers 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- 229920002125 Sokalan® Polymers 0.000 claims description 6
- 239000003921 oil Substances 0.000 claims description 6
- 235000011187 glycerol Nutrition 0.000 claims description 5
- RJZNPROJTJSYLC-LLINQDLYSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O RJZNPROJTJSYLC-LLINQDLYSA-N 0.000 claims description 4
- UIVPNOBLHXUKDX-UHFFFAOYSA-N 3,5,5-trimethylhexyl 3,5,5-trimethylhexanoate Chemical compound CC(C)(C)CC(C)CCOC(=O)CC(C)CC(C)(C)C UIVPNOBLHXUKDX-UHFFFAOYSA-N 0.000 claims description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 4
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 4
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 4
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims description 4
- 229960001631 carbomer Drugs 0.000 claims description 4
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 230000003750 conditioning effect Effects 0.000 claims description 4
- 238000004945 emulsification Methods 0.000 claims description 4
- 229940100554 isononyl isononanoate Drugs 0.000 claims description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims description 4
- 229960003966 nicotinamide Drugs 0.000 claims description 4
- 235000005152 nicotinamide Nutrition 0.000 claims description 4
- 239000011570 nicotinamide Substances 0.000 claims description 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims description 4
- 235000019198 oils Nutrition 0.000 claims description 4
- 229940101267 panthenol Drugs 0.000 claims description 4
- 235000020957 pantothenol Nutrition 0.000 claims description 4
- 239000011619 pantothenol Substances 0.000 claims description 4
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 4
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 4
- 238000010792 warming Methods 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims description 3
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 3
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 3
- 244000146462 Centella asiatica Species 0.000 claims description 3
- 235000004032 Centella asiatica Nutrition 0.000 claims description 3
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 3
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims description 3
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical class OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 3
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims description 3
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 3
- 229940036350 bisabolol Drugs 0.000 claims description 3
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 3
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 3
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical class [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 claims description 3
- 229940082500 cetostearyl alcohol Drugs 0.000 claims description 3
- WWYHAQDAMPXWSI-UHFFFAOYSA-N dodecan-1-ol;methane Chemical compound C.CCCCCCCCCCCCO WWYHAQDAMPXWSI-UHFFFAOYSA-N 0.000 claims description 3
- XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 claims description 3
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims description 3
- 229960005323 phenoxyethanol Drugs 0.000 claims description 3
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 claims description 3
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 claims description 3
- 229960003415 propylparaben Drugs 0.000 claims description 3
- 239000003813 safflower oil Substances 0.000 claims description 3
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontyl alcohol Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims description 3
- 229940042585 tocopherol acetate Drugs 0.000 claims description 3
- LADGBHLMCUINGV-UHFFFAOYSA-N tricaprin Chemical compound CCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCC)COC(=O)CCCCCCCCC LADGBHLMCUINGV-UHFFFAOYSA-N 0.000 claims description 3
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 2
- 239000004475 Arginine Substances 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- 229910019142 PO4 Inorganic materials 0.000 claims description 2
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
- 244000044822 Simmondsia californica Species 0.000 claims description 2
- 235000004433 Simmondsia californica Nutrition 0.000 claims description 2
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims description 2
- 241001135917 Vitellaria paradoxa Species 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- 238000003556 assay Methods 0.000 claims description 2
- 229920001577 copolymer Polymers 0.000 claims description 2
- 230000000249 desinfective effect Effects 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 239000003974 emollient agent Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 230000001804 emulsifying effect Effects 0.000 claims description 2
- 150000002148 esters Chemical class 0.000 claims description 2
- 239000010685 fatty oil Substances 0.000 claims description 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 2
- 235000021317 phosphate Nutrition 0.000 claims description 2
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims description 2
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims description 2
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims description 2
- 229940113124 polysorbate 60 Drugs 0.000 claims description 2
- 229910052700 potassium Inorganic materials 0.000 claims description 2
- 239000011591 potassium Substances 0.000 claims description 2
- 229960003975 potassium Drugs 0.000 claims description 2
- 235000007686 potassium Nutrition 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 230000002335 preservative effect Effects 0.000 claims description 2
- 235000005713 safflower oil Nutrition 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- 229940074410 trehalose Drugs 0.000 claims description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 2
- 239000000230 xanthan gum Substances 0.000 claims description 2
- 229940082509 xanthan gum Drugs 0.000 claims description 2
- 229920001285 xanthan gum Polymers 0.000 claims description 2
- 235000010493 xanthan gum Nutrition 0.000 claims description 2
- 244000020998 Acacia farnesiana Species 0.000 claims 1
- 235000003074 Acacia farnesiana Nutrition 0.000 claims 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 claims 1
- 244000170916 Paeonia officinalis Species 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- YAVVGPBYBUYPSR-UHFFFAOYSA-N benzene;oxygen Chemical compound [O].C1=CC=CC=C1 YAVVGPBYBUYPSR-UHFFFAOYSA-N 0.000 claims 1
- 229940081733 cetearyl alcohol Drugs 0.000 claims 1
- 239000000835 fiber Substances 0.000 claims 1
- -1 resin acid ester Chemical class 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract description 4
- 239000012752 auxiliary agent Substances 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 description 12
- 240000005001 Paeonia suffruticosa Species 0.000 description 6
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 6
- 230000037394 skin elasticity Effects 0.000 description 5
- 230000006872 improvement Effects 0.000 description 4
- 230000008859 change Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- 238000010835 comparative analysis Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000010191 image analysis Methods 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 210000001747 pupil Anatomy 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000000216 zygoma Anatomy 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 235000018330 Macadamia integrifolia Nutrition 0.000 description 1
- 240000000912 Macadamia tetraphylla Species 0.000 description 1
- 235000003800 Macadamia tetraphylla Nutrition 0.000 description 1
- 241001106477 Paeoniaceae Species 0.000 description 1
- 241001529246 Platymiscium Species 0.000 description 1
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000003005 anti-senility effect Effects 0.000 description 1
- 230000001153 anti-wrinkle effect Effects 0.000 description 1
- 125000002138 bisabolol group Chemical group 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229940071826 hydroxyethyl cellulose Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229940075495 isopropyl palmitate Drugs 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000010466 nut oil Substances 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000009758 senescence Effects 0.000 description 1
- 230000036548 skin texture Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to cosmetic technical field; specifically related to a kind of peony seed oil anti-apolexis composition and preparation method thereof; peony seed oil anti-apolexis composition of the invention includes peony seed oil and acetyl group hexapeptide 8 and auxiliary agent; compounded in the ratio for limiting by by peony seed oil and acetyl group hexapeptide 8; resulting composition has good anti-aging effects; peony seed oil can act synergistically with acetyl group hexapeptide 8 under ratio of the invention, give full play to the effect of its activity of fighting against senium.
Description
Technical field
The present invention relates to cosmetic technical field, and in particular to a kind of peony seed oil anti-apolexis composition and its preparation side
Method.
Background technology
Tree peony (Classification system：Paeonia suffruticosa Andr.) it is Paeoniaceae, Chinese herbaceous peony platymiscium, it is perennial
Machaka.Spend beautiful in colour, it is splendid, have the good reputation of " king in spending ".In Qing Dynasty's last years of a dynasty or reign, tree peony was just once taken as
The national flower of China.Peony seeds are the elite crystallizations of peony plant, have been passed on outside all characteristics that tree peony has in itself, and it more has certainly
The medicine and nutritional ingredient of oneself uniqueness.Up to more than 90%, especially estimable is it to peony seed oil unsaturated fatty acid content
Middle polyunsaturated fatty acid --- leukotrienes (category ω -3 series) content, more than 40%, is 140 times of olive oil.Peony seed oil is
The distinctive woody macadamia nut oil of China, there is fabulous Nutritional Nursing Care to act on to skin, can obviously improve skin epidermal cells circulation
Function, promotes the microcirculation of capillary of skin, and the carrying out of anti-lipid peroxidation effect improves metabolism, delay
Skin senescence process, there is good anti-wrinkle effect.
Peony seed oil has nutritive value and good beautifying and antisenility effect very high, but does not have tree peony in the prior art
Seed oil is combined for manufacturing anti-aging cosmetics with other components.
The content of the invention
The present invention is directed to problems of the prior art, there is provided a kind of anti-aging cosmetics composition and its preparation side
Method.
The present invention is achieved through the following technical solutions the purpose：
A kind of anti-aging cosmetics composition, is made up of the component of following percetage by weight：
Wherein, the emulsifying agent is PEG-100 stearates, the smooth stearate of sorb, polysorbate -60, C12-13
Any one in alcohol phosphate potassium or two or more mixtures.
Wherein, the thickener is hydroxyethyl cellulose, Carbomer, xanthan gum, PAA/acryloyldimethyl ox sulphur
Any one in sour sodium copolymer or two or more mixtures.
Wherein, the emollient be cetostearyl alcohol, isopropyl palmitate, isononyl isononanoate, dimethyl silicone polymer,
Ring five dimethyl silicone polymer, caprylic/capric triglyceride, jojoba seed oil, grape-kernel oil, Butyrospermum parkii fruit fatty oil, safflower
Any one in seed oil, saualane or two or more mixtures.
Wherein, the NMF is any one in glycerine, butanediol, Sodium Hyaluronate, panthenol, trehalose or two
Plant the mixture of the above.
Wherein, the skin conditioning agent is bisabolol, tocopherol acetate, niacinamide, 3-o- ethylascorbyls, product
Any one in the careless extract of snow or two or more mixtures.
Wherein, the PH conditioning agents are any one in triethanolamine, arginine, NaOH or two or more
Mixture.
Wherein, the preservative is any one in methyl hydroxybenzoate, Nipasol, Phenoxyethanol, Sensiva SC50
Or two or more mixtures.
Wherein, the solvent is water.
A kind of preparation method of anti-aging cosmetics composition, comprises the following steps：
(1) various raw materials in precise formula, are held with vessel that are clean and disinfecting；
(2) will by water, glycerine, butanediol, Carbomer, Sodium Hyaluronate, C12-13 alcohol phosphates potassium, niacinamide, panthenol,
The A phases raw material of trehalose composition is added in vacuum emulsification pot, after stirring is warming up to 80~85 DEG C, is stirred, and is incubated standby
With；
(3) will be by PEG-100 stearates, isopropyl palmitate, isononyl isononanoate, dimethyl silicone polymer, oxybenzene
Propyl ester, caprylic/capric triglyceride, safflower seed oil, cetostearyl alcohol, saualane, peony seed oil, bisabolol, tocopherol second
Acid esters, methyl hydroxybenzoate, the B phases raw material of ring five dimethyl silicone polymer composition are added in oil cauldron, and stirring is warming up to 80~85 DEG C, fills
Divide and stir, be incubated standby；
(4) B phases raw material is pumped into vacuum emulsification pot, after emulsifying 5-8 minutes, is stirred, constant temperature stirring
Froth breaking is lowered the temperature after 10 minutes；
(5) below when being cooled to 50 DEG C, C phase raw material triethanolamines are added, is discharged after stirring, stood；
(6) below when being cooled to 40 DEG C, add by 3-o- ethylascorbyls, Gotu Kola P.E, Argireline,
The D phase raw materials of Phenoxyethanol, Sensiva SC50 composition, discharge after stirring, stand；After the assay was approved, it is filling, system
Obtain anti-aging cosmetics composition.
Compared with prior art, the present invention has the advantages that：The present invention is by by peony seed oil and acetyl group six
Peptide -8 is compounded in the ratio for limiting, and resulting composition has good anti-aging effects, the tree peony under ratio of the invention
Seed oil can act synergistically with Argireline, give full play to the effect of its activity of fighting against senium.
Specific embodiment
Below in conjunction with specific embodiment, the present invention will be described in detail.
Embodiment 1.
The present embodiment provides a kind of anti-aging cosmetics composition, is respectively grouped point and adding proportion is as shown in table 1.
Table 1
Embodiment 2.
The present embodiment provides a kind of anti-aging cosmetics composition, is respectively grouped point and adding proportion is as shown in table 2.
Table 2
Embodiment 3.
The present embodiment provides a kind of anti-aging cosmetics composition, is respectively grouped point and adding proportion is as shown in table 3.
Table 3
Comparative example 1.
The present embodiment provides a kind of cosmetic composition of independent addition peony seed oil, be respectively grouped point and adding proportion such as
Shown in table 4.
Table 4
Comparative example 2.
The present embodiment provides a kind of cosmetic composition of independent addition Argireline, is respectively grouped point and addition is compared
For example shown in table 5.
Table 5
Comparative example 3.
The present embodiment provides a kind of blank cosmetic composition, is respectively grouped point and adding proportion is as shown in table 6.
Table 6
Checking test.
First, comparative example and embodiment are cream, and according to QB/T1857 (O/W types), physical and chemical index test result is as follows：
1. outward appearance：White or faint yellow lotion.
2.pH values：5.5-6.8.
3. heat-resistant stability is investigated:(40 ± 1) DEG C keep 24h, qualified without water-oil separating phenomenon after recovery room temperature.
4. resist cold study on the stability:(﹣ 8 ± 2) DEG C keeps 24h, qualified without water-oil separating phenomenon after recovery room temperature.
2nd, the test of dermatoglyph degree and skin elasticity test
Test population：Average age is the person 100 that has wrinkle of 35-45 Sui.Wherein, male 30, female 70, skin is good for
Health not damaged.Each embodiment and each 20 subjects of comparative example.
Dermatoglyph degree is tested.
(1) Example and comparative example cosmetics.
(2) at selection subject face left and right cheekbone, nose and pupil intersection or so at cheek, temple and corners of the mouth intersection
Left and right sides is used as pilot region.
(3) skin image analysis system (Skin Visiometer SV600) determination experiment is used by technical staff first
The dermatoglyph degree before cosmetics is smeared at position, and every is surveyed five times, is averaged.
(4) subject uses skin image analysis system (Skin Visiometer after continuously using cosmetics four weeks
SV600 dermatoglyph degree) is tested.
(5) numerical value that statistics subject position measures every time, using the 0th week as benchmark, comparative analysis its skin line
Reason rate of change, to evaluate the improvement situation of embodiment and comparative example cosmetics to dermatoglyph.(every subject per is same
One technical staff measures)
After using the said goods surrounding (28 days), the situation of data statistics is as shown in table 7.
Table 7
Skin elasticity is tested.
Under the guidance of technical staff, embodiment and comparative example cosmetics are used by tested crowd, then use skin bullet
Property tester (Cutometer dual MPA580) determine smear position elastic numerical value change situation.(every subject per
All it is that the same technical staff measures)
(1) Example and comparative example cosmetics.
(2) at selection subject face left and right cheekbone, nose and pupil intersection or so at cheek, temple and corners of the mouth intersection
Left and right sides is used as pilot region.
(3) smear twice sooner or later daily, during experiment, subject can not smear any other cosmetics.
(4) subject it is continuous using embodiment and comparative example cosmetics before and after, the contrast of skin elasticity numerical value.
(5) numerical value that statistics subject position measures every time, using the 0th week as benchmark, comparative analysis its skin bullet
Property rate of change, to evaluate the improvement situation of embodiment and comparative example cosmetics to skin elasticity.
After using the said goods surrounding (28 days), the situation of data statistics is as shown in table 8.
Table 8
Knowable to above test result：The subject of comparative example using after 4 weeks, the elasticity and texture improvement of skin
Typically, the subject of embodiment is used after using 4 weeks, and skin elasticity and texture improve substantially (P ＜ 0.05), illustrate product
Anti-aging effects be there is obvious (P ＜ 0.05) to be lifted.
Embodiment described above only expresses several embodiments of the invention, and its description is more specific and detailed, but simultaneously
Therefore the limitation to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for one of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Shield scope.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Claims (10)
1. a kind of anti-aging cosmetics composition, is made up of the component of following percetage by weight：
2. anti-aging cosmetics composition according to claim 1, it is characterised in that the emulsifying agent is that PEG-100 is hard
In the smooth stearate of resin acid ester, sorb, polysorbate -60, C12-13 alcohol phosphate potassium any one or it is two or more
Mixture.
3. anti-aging cosmetics composition according to claim 1, it is characterised in that the thickener is hydroxy ethyl fiber
In element, Carbomer, xanthan gum, PAA/sodium acryloyldimethyl taurate copolymers any one or it is two or more
Mixture.
4. anti-aging cosmetics composition according to claim 1, it is characterised in that the emollient is cetearyl alcohol
Alcohol, isopropyl palmitate, isononyl isononanoate, dimethyl silicone polymer, ring five dimethyl silicone polymer, caprylic/capric glycerine
Any one or two kinds in three esters, jojoba seed oil, grape-kernel oil, Butyrospermum parkii fruit fatty oil, safflower seed oil, saualane with
On mixture.
5. anti-aging cosmetics composition according to claim 1, it is characterised in that the NMF is glycerine, fourth two
Any one in alcohol, Sodium Hyaluronate, panthenol, trehalose or two or more mixtures.
6. anti-aging cosmetics composition according to claim 1, it is characterised in that the skin conditioning agent is opopanax
In alcohol, tocopherol acetate, niacinamide, 3-o- ethylascorbyls, Gotu Kola P.E any one or it is two or more
Mixture.
7. anti-aging cosmetics composition according to claim 1, it is characterised in that the PH conditioning agents are three ethanol
Any one in amine, arginine, NaOH or two or more mixtures.
8. anti-aging cosmetics composition according to claim 1, it is characterised in that the preservative be methyl hydroxybenzoate,
Any one in Nipasol, Phenoxyethanol, Sensiva SC50 or two or more mixtures.
9. anti-aging cosmetics composition according to claim 1, it is characterised in that the solvent is water.
10. a kind of preparation method of anti-aging cosmetics composition, it is characterised in that comprise the following steps：
(1) various raw materials in precise formula, are held with vessel that are clean and disinfecting；
(2) will be by water, glycerine, butanediol, Carbomer, Sodium Hyaluronate, C12-13 alcohol phosphates potassium, niacinamide, panthenol, marine alga
The A phases raw material of sugar composition is added in vacuum emulsification pot, after stirring is warming up to 80~85 DEG C, is stirred, and is incubated standby；
(3) will by PEG-100 stearates, isopropyl palmitate, isononyl isononanoate, dimethyl silicone polymer, Nipasol,
Caprylic/capric triglyceride, safflower seed oil, cetostearyl alcohol, saualane, peony seed oil, bisabolol, tocopherol acetate,
Methyl hydroxybenzoate, the B phases raw material of ring five dimethyl silicone polymer composition are added in oil cauldron, and stirring is warming up to 80~85 DEG C, fully stirs
Mix uniform, be incubated standby；
(4) B phases raw material is pumped into vacuum emulsification pot, after emulsifying 5-8 minutes, is stirred, constant temperature stirring froth breaking
Lower the temperature after 10 minutes；
(5) below when being cooled to 50 DEG C, C phase raw material triethanolamines are added, is discharged after stirring, stood；
(6) below when being cooled to 40 DEG C, add by 3-o- ethylascorbyls, Gotu Kola P.E, Argireline, benzene oxygen
The D phase raw materials of ethanol, Sensiva SC50 composition, discharge after stirring, stand；After the assay was approved, it is filling, it is obtained anti-
Aging cosmetic composition.
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| CN111939116A (en) * | 2020-08-18 | 2020-11-17 | 东晟源研究院(广州)有限公司 | Anti-aging composition and preparation method thereof |
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