CN106880567A - Skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy - Google Patents
Skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention belongs to daily chemical products technical field, and in particular to a kind of skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy.The skin care compositions, is mainly made up of the raw material of following weight portion：1 part of 14 parts of narcissus extract, 13 parts of algin, 0.5 2 parts of grape pomace extract, 0.5 2 parts of Gotu Kola P.E and niacinamide.The cosmetics, containing skin care compositions of the present invention, the skin care compositions accounts for the 5 15% of the cosmetics gross weight.Significantly, outward appearance, inherent quality can maintain a long-term stability, and easy to use for the cosmetics whitening, light spot and senile-resistant efficacy.
Description
Technical field
The invention belongs to daily chemical products technical field, and in particular to a kind of shield with whitening, light spot and senile-resistant efficacy
Skin composition and cosmetics.
Background technology
When skin is irradiated by ultraviolet, the melanin of decider's skin color will be produced and discharge, so as to cause color
It is plain calm excessive so that skin color is integrally dimmed or the skin splash such as brown, yellowish-brown, black occurs.Skin splash master
To include following several：Chloasma, is mainly shown as that yellowish-brown or the greyish black color spot that size shape differs occurs in face, often symmetrical
The positions such as volume, face, cheek, nose and upper lip are distributed in, skin is not higher by, clear border, the course of disease are slow, and long-term existence, the several years does not take off,
Often aggravated after Exposure to Sunlight；Freckle, is typically distributed about the region that face is easily arrived by solar radiation, is mainly caused by genetic cause；
Blackspot, is also butterfly macules, concentrates on two cheeks, it appears that just as a butterfly for expansion, and main cause is that excessive ultraviolet shines
Penetrate, skin is stimulated, cause the propagation of skin bottom melanocyte, produce excessive melanin；Senile plaque expelling, it is a kind of senile
Cutaneous lesions, are medically called seborrhoic keratosis；Sunburn, is that skin occurs erythema, oedema, goes out after sunlight excessive radiation
Existing cutaneous pigmentation；Mercury spot, due to long-term use mercury cosmetic, caused skin blacks；Cyasma, due to pregnancy
The pigmentation of generation.
The building-up process of melanin forms DOPA quinone for tyrosine is acted on the tyrosinase in cell, so as to produce black
Pigment.Therefore, suppress the partially synthetic process of melanin, be to prevent skin darkening so as to reduce the synthesis of melanin itself, carry
The effective way of skin lightening color, is also the Main way of current research.At present, the skin whitener developed can suppress in black
The tyrosinase activity played an important role in element generation, so that the amount of melanin is reduced, but the problem of this skin whitener
It is that there is excitant to skin.
The content of the invention
In order to solve the problems, such as prior art, an object of the present invention is to provide a kind of whitening, light spot and anti-ageing
The skin care compositions of old effect；The second purpose is to provide the cosmetics with whitening, light spot and senile-resistant efficacy.
An object of the present invention is achieved through the following technical solutions：
A kind of skin care compositions, is mainly made up of the raw material of following weight portion：
1-4 parts of narcissus extract, algin 1-3 parts, 0.5-2 parts, Gotu Kola P.E 0.5-2 parts of grape pomace extract
And niacinamide 0.5-2 parts.
Narcissus extract, is a kind of by Japan's QDA certifications, and spending in vain with white-skinned face function, contains new ideas whitening
Active ingredient；Melanocortin can be suppressed, suppress the synthesis and release of melanin；Suppress ripe melanosome to migrate to the table of skin
Layer, reduces cutaneous pigmentation；Substantially reduce blackspot, the purification colour of skin, Kohakuhi that pigmentation is caused.
Algin, can promote EGF and the combination of its Receptor EGFR, improve the aging continuous aging of epidermis adult stem cell
The ability of mobilization, and then promote promoting epidermization and improve vitality；Effectively help skin repair reconstruction, anti-inflammatory, releive, heal work
With.
Grape pomace extract, rich in anthocyanidin, pyrogallol and catechin, strong antioxidant remove free radical
Ability be 50 times of vitamin E, be ascorbic 20 times, can anti-inflammatory, antiallergy, resist ultraviolet radiation, promote blood
Microcirculation；Effectively suppress metal proteinase activity, prevent collagen degradation.
Gotu Kola P.E, can stimulate deep skin cell to substitute, and compact epidermis and corium coupling part can become skin
Softness, helps to solve cutis laxa phenomenon, makes skin smooth flexible；Collagen is formed in promoting skin corium, makes fiber
Protein renaturation, reconnect is got up, and skin is reached smooth effect of compacting；Also assist in impaired organization healing and consolidation flesh
Skin.The close connection between epidermis and corium can be promoted, the increase of fat cell can be suppressed again, prevent hydroderma and fertilizer
It is fat.
Niacinamide is the part of cozymase and codehydrogenase Ⅱ, plays a part of to pass hydrogen in biological oxidation respiratory chain, can be promoted
Enter biological oxidation process and tissue metabolism, to maintaining the complete of normal structure (particularly skin, alimentary canal and nervous system)
Whole property plays an important roll；Effect in terms of skin anti-aging mitigates and prevents skin to be produced in early stage aging course
Colour of skin dimness, jaundice, famished look；Impaired Stratum corneum lipids barrier can also be repaired, skin resistance is improved；There is deep layer simultaneously
Water lock effect.
According to the specific embodiment of the invention：The narcissus extract is extracted by the following method：By daffodil
Petal is crushed, and adds the 50-98%v/v ethanol solutions of 4-10 times of narcissus petal weight, soaks 12-48h, is then heated to reflux carrying
Take 2-3 times, each reflux extracting time is 2-4h, extract solution filtering is condensed into medicinal extract, adds water molten after the recovered ethanol of filtrate
Solution, it is in mutually colourless to be then extracted to water with chloroform, and gained chloroform extract is dried after removing solvent, obtains final product the narcissus and extracts
Thing.
According to the specific embodiment of the invention：The grape pomace extract is extracted by the following method：By grape
Pericarp is crushed, and adds the inorganic acid of 5-10 times of grape pomace weight water-soluble, and the water-soluble mass fraction of the inorganic acid is 0.3-
0.7%；Maintain temperature at 50-60 DEG C, extract 2-3 hours, filter to take supernatant, concentrate, be dried to obtain the grape pomace and carry
Take thing；
According to the specific embodiment of the invention：The Gotu Kola P.E is extracted by the following method：By centella
Crush, add the 50-98%v/v ethanol of 2-10 times of centella weight, heating extraction 1-3 times, each 30-180min, merging is carried
Liquid is taken, centrifuging and taking supernatant is concentrated, is dried to obtain the Gotu Kola P.E.
The preparation method of composition of the present invention is：Each raw material is well mixed, that is, obtains the skin care compositions.
The second object of the present invention is achieved by the following technical solution：A kind of cosmetics, containing of the present invention
Skin care compositions, the skin care compositions accounts for the 5-15% of the cosmetics gross weight.
For the ease of using the cosmetics, preferred technical scheme is：Described cosmetics are cream kind or type of latex type
Cosmetics.
In order that the structure and quality of the cosmetics are more stable, preferred technical scheme is：The cosmetics also contain
Account for the moisturizing of emollient, the emulsifying agent of 3-6%, the nertralizer of 0.2-1% and the 12-18% of the cosmetics gross weight 7-11%
Agent, balance of water.
According to one embodiment of present invention：The emollient is isononyl isononanoate, double-PEG-18 methyl ethers dimethyl
One or more in silane and Butyrospermum parkii fruit fat；The NMF is butanediol, water lock magnetite, beta glucan and hyalomitome
One or more in sour sodium；The nertralizer is triethanolamine, and the emulsifying agent is the acid of the methyl of polyglycereol -3 distearyl
Ester.
Moisture content combination angle is assisted in water lock magnetite, natural moisture preserving agent and emollients of a kind of extraction from sugarcane carbohydrate synthesis
Keratin in matter layer, with up to moistening effect.With reparation epidermal layer cells, lifting skin moisturizing ability, via biochemistry
The isomerization D- glucans of technology manufacture, with the composition structure close with human keratinous layer, using can be with ε-ammonia on skin
Base acid functional group is combined, and is firmly combined just as magnetite, long-acting can maintain the hydromagnetic field energy power of skin.
Isononyl isononanoate, unique many methyl branch structures, silk-like feeling, dry and comfortable and extremely soft feel is splendid
Emollient.Viscosity is low, and skin sense is salubrious, without greasy feeling.
The methyl distearate of polyglycereol -3, as emulsifying agent, can improve in emulsion between various composition phases
Surface tension, be allowed to be formed the material of uniform and stable dispersion or emulsion.Emulsifying agent is surface reactive material, molecule
In simultaneously there is hydrophilic group and lipophilic group, it is gathered on oil/water interface, can reduce interfacial tension and reduction forms emulsion
Required energy, so as to improve the energy of emulsion.
Beta glucan, it can activated macrophage, neutrophils etc., therefore leukin, cell point can be improved
The content of element and distinct antibodies is split, the immune system of body is stimulated comprehensively, beta glucan can produce the lymphocyte of injured body
The ability of raw cell factor (IL-1) recovers rapidly normal, effectively adjusts human body immune function.Additionally, beta glucan has removing
Free radical and radiation-resistant effect.
Cetostearyl alcohol, as matrix, is particularly suitable for cream and emulsion suitable for all kinds of cosmetics；In medicine,
Can be directly used for W/O emulsifying agent lotions, ointment bases etc..
Triethanolamine is used as emulsifying agent, NMF, humidizer, thickener, pH poising agents in cosmetics.Triethanolamine is
The most frequently used nertralizer containing the acidity high-molecular gel such as Carbomer, triethanolamine is neutralized by with the carboxyl such as Carbomer, is formed
The macromolecular structure of stabilization, reaches the application effect of thickening and moisturizing.Carbomer, generally neutralizes into salt by card ripple, makes curling
Molecule is thickened because electric repulsion opens.
Sodium Hyaluronate, can play the protection skin effect of uniqueness, and skin moisturizing can be kept smooth, fine and smooth tender, be rich in
Elasticity, the effect with wrinkle resistant, crease-resistant, beauty and health care and recovery skin physiology function.
According to one embodiment of present invention：The NMF is butanediol, water lock magnetite, beta glucan and hyaluronic acid
During sodium, four kinds of part by weight of material are 40-60：20-40：10-30：1, when the NMF lacks one or more of which
When, surplus materials still according to aforementioned proportion；The emollient is isononyl isononanoate, double-PEG-18 methyl ethers dimethyl-silicons
When alkane and Butyrospermum parkii fruit fat, three kinds of part by weight of material are 1.5-3：1-2：1, when the emollient lack one of which or
When various, surplus materials still according to aforementioned proportion.
In order to extend the shelf-life of the cosmetics, preferred technical scheme is：The cosmetics are also containing accounting for describedization
The preservative of cosmetic gross weight 0.2-0.5% and/or the thickener of 3-6%.
The preparation method of cosmetics of the present invention is：After each raw material is mixed, 40-50 DEG C is heated to, maintains temperature to stir
Mix 20-40 minutes, obtain the cosmetics.
In order that the cosmetics mixing is evenly, preferred technical scheme is that raw material mixed process is using nitrogen
Carried out in the environment of pressurization, pressure is 120-150kPa.
Beneficial effects of the present invention are：
1st, skin care compositions of the present invention, can suppress the synthesis and release of melanin；Pigmentation is substantially reduced to make
Into blackspot, purification the colour of skin, Kohakuhi；Collagen is formed in promoting skin corium, regenerates fibrin, helps to solve
Cutis laxa phenomenon, makes skin smooth flexible；Improve skin resistance；Each composition of composition of the present invention is in whitening, light
Spot and anti-aging aspect play synergy, and natural extract is gentle to skin, substantially nonirritant.During specific production, can
According to conventional production process, skin care compositions of the present invention to be added in the cosmetics.It is whitening of the invention, light
The composition fragrant of spot and anti-aging, skin sense preferably, is added to cream, emulsion, mildy wash, cleansing cream, shampoo, toner
Or in the cosmetics such as firming lotion, bath agent, by controlling rational addition and appropriate process conditions, will not be to cosmetics
Institutional framework damage, the stability to cosmetics will not bring detrimental effect, will not cause the quality such as discoloration, layering
Problem.
2nd, present invention also offers a kind of cosmetics, the cosmetics include oil phase, water phase and skin care of the present invention
Composition is constituted, effect of whitening, light spot and anti-aging, additionally, the cosmetic product outward appearance, inherent quality can keep long-term
Stabilization.
Specific embodiment
With reference to embodiment, present disclosure is further illustrated.It should be appreciated that implementation of the invention is not limited to
In the following examples, any formal accommodation and/or change made to the present invention fall within the scope of the present invention.
In the present invention, if not refering in particular to, all of part, percentage are unit of weight, and all of equipment and raw material etc. are
It is commercially available or the industry is conventional.Method in following embodiments, unless otherwise instructed, is the routine of this area
Method.
Embodiment 1
A kind of skin care compositions, is mainly made up of the raw material of following weight portion：
Narcissus extract 1g, algin 1g, grape pomace extract 2g, Gotu Kola P.E 2g and niacinamide 0.5g.
The preparation method of composition described in the present embodiment is：Each raw material is well mixed, that is, obtains the skin care compositions.
Embodiment 2
A kind of skin care compositions, is mainly made up of the raw material of following weight g：
Narcissus extract 4g, algin 3g, grape pomace extract 0.5g, Gotu Kola P.E 0.5g and niacinamide 2g.
The narcissus extract is extracted by the following method：The petal of daffodil is crushed, narcissus petal weight is added
The 50%v/v ethanol solutions of 4 times of amount, soak 12h, then heating and refluxing extraction 2 times, and each reflux extracting time is 4h, is extracted
Liquid is filtered, and medicinal extract is condensed into after the recovered ethanol of filtrate, is dissolved in water, and it is in mutually colourless, gained chlorine to be then extracted to water with chloroform
Imitative extract is dried after removing solvent, obtains final product the narcissus extract.
The grape pomace extract is extracted by the following method：Grape pomace is crushed, uva tare weight is added
The inorganic acid of 10 times of amount is water-soluble, and the water-soluble mass fraction of the inorganic acid is 0.3%；Maintain temperature at 50 DEG C, extract 3 hours,
Supernatant is filtered to take, concentrated, be dried to obtain the grape pomace extract.
The Gotu Kola P.E is extracted by the following method：Centella is crushed, 2 times of centella weight is added
98%v/v ethanol, heating extraction 180min, centrifuging and taking supernatant is concentrated, is dried to obtain the Gotu Kola P.E.
The preparation method of composition described in the present embodiment is：Each raw material is well mixed, that is, obtains the skin care compositions.
Embodiment 3
A kind of skin care compositions, is mainly made up of the raw material of following weight portion：
Narcissus extract 3g, algin 2g, grape pomace extract 1g, Gotu Kola P.E 1.5g and niacinamide 1.5g.
The narcissus extract is extracted by the following method：The petal of daffodil is crushed, narcissus petal weight is added
The 98%v/v ethanol solutions of 10 times of amount, soak 48h, then heating and refluxing extraction 3 times, and each reflux extracting time is 2h, is extracted
Liquid is filtered, and medicinal extract is condensed into after the recovered ethanol of filtrate, is dissolved in water, and it is in mutually colourless, gained chlorine to be then extracted to water with chloroform
Imitative extract is dried after removing solvent, obtains final product the narcissus extract.
The grape pomace extract is extracted by the following method：Grape pomace is crushed, uva tare weight is added
The inorganic acid of 5 times of amount is water-soluble, and the water-soluble mass fraction of the inorganic acid is 0.7%；Maintain temperature at 60 DEG C, extract 2 hours, mistake
Leaching supernatant, concentrates, is dried to obtain the grape pomace extract.
The Gotu Kola P.E is extracted by the following method：Centella is crushed, 10 times of centella weight is added
50%v/v ethanol, heating extraction 3 times, each 30min merges extract solution, centrifuging and taking supernatant, concentrate, be dried to obtain it is described
Gotu Kola P.E.
The preparation method of composition described in the present embodiment is：Each raw material is well mixed, that is, obtains the skin care compositions.
Embodiment 4
A kind of tender skin breast, the skin care cream contains skin care compositions 5g described in embodiment 2, emollient 7g, emulsifying agent 3g, in
With agent 0.2g and NMF 12g, water 79.8g；The NMF be butanediol, water lock magnetite, beta glucan and Sodium Hyaluronate,
And four kinds of part by weight of material are 40：20：30：1；The emollient is isononyl isononanoate, double-PEG-18 methyl ethers diformazans
Base silane and Butyrospermum parkii fruit fat, and three kinds of part by weight of material are 1.5：2：1；The nertralizer is triethanolamine, described
Emulsifying agent is the methyl distearate of polyglycereol -3.
The preparation method of tender skin breast is described in the present embodiment：After each raw material is mixed, 40-50 DEG C is heated to, maintains temperature
Stirring 20-40 minutes, raw material mixed process is carried out in using the environment of the pressurization of nitrogen, and pressure is 120-150kPa, is obtained
The skin care cream.
Tender skin breast described in the present embodiment, through repeatedly heat-resisting (40 (1 DEG C, after 24 hours recover room temperatures, system is uniform), cold-resistant
(- 5~-10 DEG C, 24 hours recover room temperatures after, with experiment before without obvious Traits change) destructive test, product items sense organ refer to
Mark, physical and chemical index meet corresponding national standard.
Embodiment 5
A kind of skin care cream, the skin care cream contains skin care compositions 15g described in embodiment 3, emollient 11g, emulsifying agent 6g,
Nertralizer 1g, NMF 18g, preservative 0.2g, thickener 3g and water 45.8g；The NMF be butanediol, water lock magnetite,
Beta glucan and Sodium Hyaluronate, and four kinds of part by weight of material are 60：40：10：1；The emollient is the different nonyl of different n-nonanoic acid
Ester, double-PEG-18 methyl ethers dimethylsilanes and Butyrospermum parkii fruit fat, and three kinds of part by weight of material are 3：1：1；In described
It is triethanolamine with agent；The emulsifying agent is the methyl distearate of polyglycereol -3；The preservative is iodine propilolic alcohol fourth
Base mephenesin Carbamate and Phenoxyethanol, and two kinds of part by weight of material are 3：4；The thickener is cetostearyl alcohol and card ripple
Nurse, and two kinds of part by weight of material are 6：1.
The preparation method of skin care cream described in the present embodiment is：After each raw material is mixed, 40-50 DEG C is heated to, maintains temperature
Stirring 20-40 minutes, raw material mixed process is carried out in using the environment of the pressurization of nitrogen, and pressure is 120-150kPa, is obtained
The skin care cream.
Skin care cream described in the present embodiment, through repeatedly heat-resisting (40 (1 DEG C, after 24 hours recover room temperatures, system is uniform), cold-resistant
(- 5~-10 DEG C, 24 hours recover room temperatures after, with experiment before without obvious Traits change) destructive test, product items sense organ refer to
Mark, physical and chemical index meet corresponding national standard.
Embodiment 6
A kind of skin care cream, the skin care cream contains skin care compositions 10g described in embodiment 3, emollient 8g, emulsifying agent 6g,
Nertralizer 0.5g, NMF 15g, preservative are 0.5g, thickener 6g and water 54g；The NMF is water lock magnetite, β-Portugal gathers
Sugar and Sodium Hyaluronate, and three kinds of part by weight of material are 40：10：1；The emollient is double-PEG-18 methyl ether diformazans
Base silane and Butyrospermum parkii fruit fat, and two kinds of part by weight of material are 1：1；The nertralizer is triethanolamine, the emulsification
Agent is the methyl distearate of polyglycereol -3；The preservative is iodine propilolic alcohol butyl mephenesin Carbamate, double imidazolidinyl urea
And Phenoxyethanol, and three kinds of part by weight of material are 3：3：4；The thickener is cetostearyl alcohol and Carbomer, and two kinds
The part by weight of material is 8：1.
The preparation method of skin care cream described in the present embodiment is：After each raw material is mixed, 40-50 DEG C is heated to, maintains temperature
Stirring 20-40 minutes, raw material mixed process is carried out in using the environment of the pressurization of nitrogen, and pressure is 120-150kPa, is obtained
The skin care cream.
Skin care cream described in the present embodiment, through repeatedly heat-resisting (40 (1 DEG C, after 24 hours recover room temperatures, system is uniform), cold-resistant
(- 5~-10 DEG C, 24 hours recover room temperatures after, with experiment before without obvious Traits change) destructive test, product items sense organ refer to
Mark, physical and chemical index meet corresponding national standard.
Efficacy experiments
To verify skin care compositions of the present invention and the cosmetics in terms of moisturizing, smoothing wrinkle and recovery skin elasticity
Effect, volunteer carries out the both effectiveness test experiments of skin of face between selecting -60 years old 25 years old.
(1) laboratory sample：
Sample A is the tender skin breast described in embodiment 4；
Sample B is the skin care cream described in embodiment 5；
Sample C is the skin care cream described in embodiment 6；
Sample D be with deionized water for described skin care compositions composition in skin care cream described in embodiment 5, other compositions with
Other compositions are consistent in sample B；
Sample E is deionized water.
(2) prepare before testing：
100 volunteers of selection are randomly divided into five groups of A, B, C, D and E, every group of 20 people, respectively to sample A, B, C, D and E
Tested.Any cosmetics or topical drug can not be used within -3 days 2 days before recipient site.Before experiment, volunteer needs cleaning
Face.
(3) skin test
In experiment, every group of volunteer smears counter sample 2 times, every time respectively by the consumption for smearing 1.0mg/cm2 sooner or later daily
Uniform application, 0 week (i.e. using preceding) and it is continuous using 2 weeks, 4 weeks and 6 weeks when, the same time is by the spreader portion of subject weekly
Position is cleaned, and using U.S. VISIA face-image analyzers, carries out skin color, spot and skin aging degree analyzing.
Skin color is analyzed, and using face-image analyzer, tests skin shine, and calculate the group continuously using sample
2 weeks, 4 weeks and 6 weeks skin shows more greatly skin relative to the 0 week average value of the glossiness growth rate of skin, glossiness growth rate
The degree for bleaching is bigger, so as to reflect effect of the sample to skin-whitening.
Spot proportion grading, using face-image analyzer, tests the skin speckle gross area, and calculates the group continuously using
2 weeks, 4 weeks and 6 weeks skin of sample is relative to the 0 week average value of the spot gross area minification of skin, spot gross area minification
It is bigger, show amount of speckle reduction or the diminution of speck area, so as to reflect sample to the light spot effect of skin.
Skin aging degree analyzing, the collagen content and sanguimotor in test epiderm skin to following 2 millimeters
Distribution situation, and calculate the group continuously use 2 weeks, 4 weeks and 6 weeks skin of sample relative to the collagen content of 0 week skin and
The growth rate of the average value of the growth rate of sanguimotor distribution, collagen content and sanguimotor distribution is bigger, shows
The collagen content of skin is higher, blood circulation distribution is wider, i.e., skin condition is younger, so as to reflect that sample is anti-to skin
The effect of aging.
(4) interpretation
Skin color analyze, experimental result as shown in table 1, volunteer continuously use sample A, B and C, at the 2nd week, 4 weeks and
The glossiness growth rate of skin is significantly improved within 6 weeks, is increased greatly especially with the 4th week；Carried using skin shine after sample D
Height is slightly improved；Almost do not increased using skin shine after sample E, declined on the contrary, experiment shows of the present invention
Effect is significant of the cosmetics to skin-whitening.
Spot proportion grading, experimental result as shown in table 2, volunteer continuously use sample A, B and C, at the 2nd week, 4 weeks and
The spot gross area minification of skin is significantly improved within 6 weeks；Increase unobvious using skin speckle gross area minification after sample D；
Declined using skin skin speckle gross area minification after sample E, experiment shows that cosmetics of the present invention are imitated to light spot
Fruit is significantly.
Skin aging degree analyzing, as shown in Table 3 and Table 4, volunteer continuously uses sample A, B and C to experimental result, the
The collagen content of 2 weeks, 4 weeks and 6 weeks skin and the growth rate of sanguimotor distribution are got over and are significantly improved；Using sample D and
Collagen content and the growth rate of sanguimotor distribution be not obvious after sample E or has downward trend；Experiment shows the present invention
The cosmetics are notable to anti-aging effects.
Test result indicate that cosmetics of the present invention have remarkable effect in terms of skin-whitening, light spot and anti-aging,
The difference of D groups sample and B group samples has been free from skin care compositions of the present invention simultaneously, and D groups sample is in skin-whitening, light
Spot and anti-aging aspect do not have remarkable effect, show that the active ingredient that B group samples play a role is skin care of the present invention
Composition, shows that skin care compositions of the present invention has remarkable effect in terms of skin-whitening, light spot and anti-aging.
The glossiness growth rate of the skin of table 1
The spot gross area minification of table 2
The collagen content growth rate of table 3
The growth rate of the sanguimotor distribution of table 4
It should be noted last that, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although ginseng
The present invention is described in detail according to preferred embodiment, should be understood that and be the foregoing is only specific implementation of the invention
Mode, the protection domain being not intended to limit the present invention, it is all within the spirit and principles in the present invention, done any repair
Change, equivalent, improvement etc., should be included within the scope of the present invention.
Claims (10)
1. a kind of skin care compositions with whitening, light spot and senile-resistant efficacy, it is characterised in that main by following weight portion
Raw material is made：
1-4 parts of narcissus extract, algin 1-3 parts, 0.5-2 parts, Gotu Kola P.E 0.5-2 parts of grape pomace extract and cigarette
Acid amides 0.5-2 parts.
2. skin care compositions according to claim 1, it is characterised in that：The narcissus extract is to extract by the following method
Arrive：The petal of daffodil is crushed, the 50-98%v/v ethanol solutions of 4-10 times of narcissus petal weight are added, 12- is soaked
48h, then heating and refluxing extraction 2-3 times, each reflux extracting time is 2-4h, extract solution filtering, after the recovered ethanol of filtrate
Medicinal extract is condensed into, is dissolved in water, it is in mutually colourless to be then extracted to water with chloroform, and gained chloroform extract is done after removing solvent
It is dry, obtain final product the narcissus extract.
3. skin care compositions according to claim 1, it is characterised in that：The grape pomace extract is by the following method
Extract：Grape pomace is crushed, adds the inorganic acid of 5-10 times of grape pomace weight water-soluble, the water-soluble matter of the inorganic acid
Amount fraction is 0.3-0.7%；Maintain temperature at 50-60 DEG C, extract 2-3 hours, filter to take supernatant, concentrate, be dried to obtain institute
State grape pomace extract.
4. skin care compositions according to claim 1, it is characterised in that：The Gotu Kola P.E is to carry by the following method
Get：Centella is crushed, the 50-98%v/v ethanol of 2-10 times of addition centella weight, heating extraction 1-3 times, every time
30-180min, merges extract solution, and centrifuging and taking supernatant is concentrated, is dried to obtain the Gotu Kola P.E.
5. a kind of cosmetics, it is characterised in that contain any described skin care compositions of claim 1-4, the skincare composition
Thing accounts for the 5-15% of the cosmetics gross weight.
6. cosmetics according to claim 5, it is characterised in that described cosmetics are that cream kind or type of latex type are made up
Product.
7. cosmetics according to claim 5, it is characterised in that the cosmetics are also containing accounting for the cosmetics gross weight
The NMF of the emollient of 7-11%, the emulsifying agent of 3-6%, the nertralizer of 0.2-1% and 12-18%, balance of water.
8. cosmetics according to claim 7, it is characterised in that the emollient is isononyl isononanoate, double-PEG-18
One or more in methyl ether dimethylsilane and Butyrospermum parkii fruit fat；The NMF is butanediol, water lock magnetite, β-Portugal
One or more in glycan and Sodium Hyaluronate；The nertralizer is triethanolamine, and the emulsifying agent is the methyl of polyglycereol -3
Glucose distearate.
9. cosmetics according to claim 7, it is characterised in that the NMF is that butanediol, water lock magnetite, β-Portugal gather
When sugar and Sodium Hyaluronate, four kinds of part by weight of material are 40-60：20-40：10-30：1；The emollient is that different n-nonanoic acid is different
When nonyl ester, double-PEG-18 methyl ethers dimethylsilanes and Butyrospermum parkii fruit fat, three kinds of part by weight of material are 1.5-3：1-2：
1。
10. cosmetics according to claim 7, it is characterised in that the cosmetics are also containing accounting for the cosmetics gross weight
Measure the preservative of 0.2-0.5% and/or the thickener of 3-6%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710134445.2A CN106880567A (en) | 2017-03-08 | 2017-03-08 | Skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710134445.2A CN106880567A (en) | 2017-03-08 | 2017-03-08 | Skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy |
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| CN106880567A true CN106880567A (en) | 2017-06-23 |
Family
ID=59180485
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710134445.2A Pending CN106880567A (en) | 2017-03-08 | 2017-03-08 | Skin care compositions and cosmetics with whitening, light spot and senile-resistant efficacy |
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| CN108066269A (en) * | 2017-12-27 | 2018-05-25 | 国东启 | A kind of calmness antiallergic whitening anti-wrinkling composition, its skin care item and preparation method |
| CN110368325A (en) * | 2019-08-07 | 2019-10-25 | 中山卡丝生物科技有限公司 | A kind of anti-wrinkle composition and its preparation method and application |
| FR3110421A1 (en) * | 2020-05-19 | 2021-11-26 | International Flavors & Fragrances Inc | Narcissus poeticus extract for its cosmetic use |
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