CN106726689A - It is a kind of to prevent and treat face cream of acne and preparation method thereof - Google Patents
It is a kind of to prevent and treat face cream of acne and preparation method thereof Download PDFInfo
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- CN106726689A CN106726689A CN201611213678.3A CN201611213678A CN106726689A CN 106726689 A CN106726689 A CN 106726689A CN 201611213678 A CN201611213678 A CN 201611213678A CN 106726689 A CN106726689 A CN 106726689A
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- face cream
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- preventing
- acid
- scutelloside
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to cosmetics face cream technical field, it is specifically related to a kind of to prevent and treat face cream of acne and preparation method thereof, face cream main component is pachymaran 0.2 0.5%, glycyrrhizic acid 0.2 0.4%, scutelloside 0.1 0.2%, glycerine 15 20%, lecithin 5 7%, alginic acid 3 5%, isopropyl palmitate 10 15%, preservative 0.05 0.1%, water 45 70%, the face cream that the present invention is provided has prevention effect to whelk or damp and hot caused acne, and with good inhibiting bacteria and diminishing inflammation effect, involved composition is gently safe in invention, there is good pro-skin effect.
Description
Technical field
The invention belongs to cosmetics face cream field, and in particular to prevent and treat face cream of acne and preparation method thereof to a kind of.
Background technology
Acne and small pox are all referred to as acne.Acne is one of most common disease of Skin cosmesis, is mainly in puberty,
It is called whelk, face Blisters or acne, epifolliculitis.Induced factor mainly has 1, smegma vigorous；2nd, cleaning does not cause thoroughly
Hair follicle blocks；3rd, heredity；4th, stay up late caused smegma exception；5th, extreme climate increases smegma；6th, it is internal
Metabolism is abnormal caused by disease.
The face appearance of people is influenceed due to acne, people once grow acne, can directly be extruded with hand under normal circumstances, but
It is if extruding is improper to cause serious consequence, such as to trigger more inflammation, healing delay, residual acne print etc..Current market
On occur in that substantial amounts of product for resolving poxes, be mainly divided into following a few classes：1st, sulfur soap：Bactericidal effect is truly had to small pox inflammation, but
It is too big to skin irritatin；2nd, frosted grain：Can peel off aging cutin, but the secretion of grease can be promoted, go out acne more；3rd, wine
Essence：Only concentration reach 60%-75% alcoholic solution can be only achieved sterilization effect, on the market mostly only 40%, not only
There is no anti-acne effect to stimulate skin on the contrary；4th, zinc oxide：Suitable for sun-proof, protect skin sparing skin not by environmental stimuli,
But can blocked pore；5th, hormone：Hormone not only make one produce according to lazyness, long-term use can cause slow poisoning, because hormone without
Hole does not enter, and can precipitate into capilary, into blood circulation, declines passive protective physical fitness, can cause poisoning symptom.If improper make
With product for resolving poxes, anti-acne is not only unable to, can also cause more inflammation, therefore safely and efficiently the research and development of product for resolving poxes become ten
Divide important.
Notification number discloses a kind of acne-removing liquid, including following component for the Chinese patent of CN103006527B：Component A：Third
Glycol, xanthan gum, the first solvent；B component：Two isethionic acids amidine, vitamin B6, the second solvent；Component C：Plant extraction liquid,
Azelaic acid derivant, mother chrysanthemum dimension element, salicylic acid, ginseng extract, vitamin E, preservative.Also have in the formula that the present invention is provided
Substantial amounts of easy allergic component, local skin may occur erythema, itching, shouting pain symptom when wherein salicylic acid is used, and may lead
Cause small pox flesh more serious.
In order to further improve the security of product for resolving poxes, there is substantial amounts of Chinese medicine product for resolving poxes in the market, but due to
Traditional Chinese medicine ingredients extraction process is complicated, causes cost to raise, or is extracted using organic matter, cause a large amount of harmful substances remain or
Directly volatilization is slatterned active ingredient, influences product quality and performance.
The Chinese patent application of Publication No. 103784367A discloses a kind of with acne blackhead and the mitigation red blood silk of dispelling
External skin-care composition, mildy wash of effect and preparation method thereof, and the preparation method of tcm componentses extract is disclosed, the hair
Bright complicated component, containing various artificial-synthetic materials, and Chinese medicine employs ethanol solution extraction, but due to ethanol and Chinese medicine
Active ingredient is mutually dissolved, and belongs to volatile components, thus separate be easily caused Chinese medicine in concentration process in effectively into
Point loss or alcohol component residual, not only can not rationally utilize raw material, and a small amount of ethanol stimulation skin performance
A part of Chinese medicine effect can be offset.
The content of the invention
It is simple the invention provides a kind of composition in order to solve problems of the prior art, safety, with good
Skin-friendly face cream, it is specially a kind of to prevent and treat face cream of acne and preparation method thereof.
The present invention is implemented especially by following technical scheme.
A kind of face cream for preventing and treating acne, mainly by following mass fraction into being grouped into：It is pachymaran 0.2-0.5%, sweet
Oxalic acid 0.2-0.4%, scutelloside 0.1-0.2%, glycerine 15-20%, lecithin 5-7%, alginic acid 3-5%, palmitic acid isopropyl
Ester 10-15%, preservative 0.05-0.1%, water 45-70%.
Further, the described face cream for preventing and treating acne, by following mass fraction into being grouped into：Pachymaran
0.35%th, glycyrrhizic acid 0.3%, scutelloside 0.15%, glycerine 18%, lecithin 6%, alginic acid 4%, isopropyl palmitate
13%th, preservative 0.08%, water 58.12%.
Further, described preservative is calcium lactate.
Present invention also offers the preparation method of the described face cream for preventing and treating acne, step is：
S1：Glycerine, lecithin, alginic acid, isopropyl palmitate and water are added in emulsion tank, are heated to while stirring
85~95 DEG C, stir, obtain latex A；
S2：The latex A obtained in step S1 is cooled to 50 DEG C~55 DEG C, pachymaran, glycyrrhizic acid, scutelloside is added,
Stir, obtain mixed liquid B；
S3：The mixed liquid B obtained in step S2 is cooled to 35 DEG C~45 DEG C, preservative is added, stirred, be down to room
Temperature, obtains final product.
Further, mixing speed is 45-50r/min in step S1, S2 and S3.
Glycyrrhizic acid：The main active substances of Radix Glycyrrhizae, have functions that clearing heat and detoxicating, preventing and treating carbuncle sore tumefacting virus, can alleviate skin
Caused scorching sense, prevents and treats the generation of acne during skin allergy.
Alginic acid：Alginic acid has good absorption metallicity, and effect is dispelled to cosmetics metal residual.
Pachymaran can strengthen the immunologic function of skin, with good antiviral, anti-oxidant, anti-inflammatory effect, with
Glycyrrhizic acid uses cooperatively the antibacterial and anti-inflammation functions that can further strengthen to skin.
Scutelloside is that a kind of flavone compound separated is extracted from scutellariae,radix, with antibacterial, anti-inflammatory, Er Qiehuang
A kind of reed mentioned in ancient books glycosides can also absorb ultraviolet, and scavenging activated oxygen can suppress the generation of melanin again.Scutelloside is more with glycyrrhizic acid and Poria cocos
After sugar is used cooperatively, the antioxidation of itself can be strengthened.
The pachymaran of addition, scutelloside, glycyrrhizic acid have good bactericidal anti-inflammatory effect in the present invention, to skin acne
With good preventive and therapeutic effect.
The present invention compared with prior art, with following progress：
1st, security：The composition that the present invention is used is primarily present in nature, wherein pachymaran, scutelloside, Radix Glycyrrhizae
Acid is avirulent active Chinese drug component material, improves the safety coefficient of cosmetics than Chinese medical extract composition definitely.
2nd, anti-acne effect：Present component is disappeared using unique pachymaran, scutelloside, glycyrrhizic acid containing natural removing toxic substances
Scorching composition, uses cooperatively, and can disperse skin surface heat, reduces acne and occurs, and using refrigerant comfortable.
Specific embodiment
The present invention is further illustrated by specific examples below, those skilled in the art is become more apparent upon the technology of the present invention side
Case.Composition of the present invention is conventional products, wherein, pachymaran, glycyrrhizic acid, scutelloside：Xi'an Tianrui biotechnology
Co., Ltd；Lecithin：Henan Hua Yue chemical products Co., Ltd；Alginic acid：Shanghai is great along bio tech ltd.
Embodiment 1
A kind of face cream for preventing and treating acne, by following mass fraction into being grouped into：Pachymaran 0.35%, glycyrrhizic acid
0.3%th, scutelloside 0.15%, glycerine 18%, lecithin 6%, alginic acid 4%, isopropyl palmitate 13%, preservative calcium lactate
0.08%th, water 58.12%.
The preparation method of the described face cream for preventing and treating acne,
S1：Glycerine, lecithin, alginic acid, isopropyl palmitate and water are added in emulsion tank, are heated to while stirring
90 DEG C, stir, mixing speed is 48r/min, obtains latex A；
S2：The latex A obtained in step S1 is cooled to 53 DEG C, pachymaran, glycyrrhizic acid, scutelloside is added, stirring is equal
Even, mixing speed is 48r/min, obtains mixed liquid B；
S3：The mixed liquid B obtained in step S2 is cooled to 40 DEG C, preservative calcium lactate is added, stirred, stirring speed
It is 48r/min to spend, and is down to room temperature, is obtained final product.
Embodiment 2
A kind of face cream for preventing and treating acne, by following mass fraction into being grouped into：Pachymaran 0.5%, glycyrrhizic acid
0.2%th, scutelloside 0.2%, glycerine 15%, lecithin 7%, alginic acid 3%, isopropyl palmitate 15%, preservative calcium lactate
0.05%th, water 59.05%.
The preparation method of the described face cream for preventing and treating acne is similar to Example 1.
Embodiment 3
A kind of face cream for preventing and treating acne, by following mass fraction into being grouped into：Pachymaran 0.2%, glycyrrhizic acid
0.4%th, scutelloside 0.1%, glycerine 20%, lecithin 5%, alginic acid 5%, isopropyl palmitate 10%, preservative calcium lactate
0.1%th, water 59.2%.
The preparation method of the described face cream for preventing and treating acne is similar to Example 1.
Comparative example 1
A kind of face cream for preventing and treating acne, by following mass fraction into being grouped into：Pachymaran 0.35%, glycyrrhizic acid
0.45%th, glycerine 18%, lecithin 6%, alginic acid 4%, isopropyl palmitate 13%, preservative calcium lactate 0.08%, water
58.12%.
It is without scutelloside, the content of increase glycyrrhizic acid with the difference of embodiment 1.
The preparation method of the described face cream for preventing and treating acne is similar to Example 1.
Test example 1, safety evaluation of the present invention
Subjects：The face cream for preventing and treating acne prepared by embodiment 1-3, comparative example 1.
Tested crowd：40 people, between 15~30 years old, the people of female 20, male 20 people.
Health status：Subject meets subject's aspiration inclusion criteria without skin disease allergies.
Patch method：Try device from qualified spot, with closed patch experiment method, by tested material about 0.020ml~
In in spot examination device, external application special adhesive tape is covered on subject back to 0.025ml drops, and tested material is removed after 12 hours, observes respectively
Dermoreaction in 0.5,6,12,24,48 hours, as a result shows after removal：40 subjects are by patch test, wherein 0 occurs
Skin adverse reaction, illustrates the face cream safety for preventing and treating acne used by experiment.
Test example 2, anti-acne effect is tested
Test products：The face cream for preventing and treating acne prepared by embodiment 1-3, comparative example 1.
Tested crowd：120 people, between 15~30 years old, the people of female 60, male 60 people, random point 4 groups.
Skin health：Small pox flesh caused by various factors, causes reason 1, puberty：Skin oil and fat secretion is vigorous；
2nd, diet is bad；3rd, endocrinopathy.
Test method：After basic skin care, 0.5-1ml products are smeared, sooner or later once daily.Every group is only prevented and treated acne with one kind
Face cream, the product of other identical functions is not used, it is continuous to use 60 days observation results.
Effective evaluation standard：
(1) cure：Acne removes area more than 95%.
(2) it is effective：Acne removes area between 60-95%.
(3) effectively：Acne removes area between 10-60%.
(4) it is invalid：Acne removes area below 10%.
Result is as shown in table 1 below.
The face cream anti-acne effect for preventing and treating acne that the embodiment 1-3 of table 1 is prepared with comparative example 1
| Group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 |
| Cure | 18 | 17 | 18 | 12 |
| It is effective | 7 | 6 | 5 | 6 |
| Effectively | 5 | 7 | 7 | 6 |
| It is invalid | 0 | 0 | 0 | 6 |
From table 1 it follows that embodiment 1-3 is relative to comparative example 1, anti-acne effect is more obvious, illustrates present invention tool
There is good anti-acne effect, with good market prospects.
Test example 3, investigation on probation
Subjects：The face cream for preventing and treating acne prepared by embodiment 1-3, comparative example 1.
Tested crowd：40 people, between 15~30 years old, the people of female 20, male 20 people, random point 4 groups.
Skin health：Face has acne.
Test method：After basic skin care, appropriate this product is smeared, it is sooner or later once daily, continuous to use 3 months.Every group only
With a kind of face cream for preventing and treating acne, try out and evaluate as shown in table 2.
The face cream trial effect for preventing and treating acne that the embodiment 1-3 of table 2 is prepared with comparative example 1
From Table 2, it can be seen that being made compared to comparative example 1 using the face cream for preventing and treating acne prepared by embodiment of the present invention 1-3
Composition more preferably, simply corresponding adjustment is made in comparative example 1 by the standby face cream effect for preventing and treating acne, and its effect changes,
Illustrate that inventive formulation combination can not arbitrarily change, further illustrate compatibility of the present invention rationally, there is preferable acne removing skin-cleaning effect.
The above-described embodiments merely illustrate the principles and effects of the present invention, not for the limitation present invention.It is any ripe
The personage for knowing this technology all can carry out modifications and changes under without prejudice to spirit and scope of the invention to above-described embodiment.Cause
This, those of ordinary skill in the art is complete with institute under technological thought without departing from disclosed spirit such as
Into all equivalent modifications or change, should be covered by claim of the invention.
Claims (5)
1. a kind of face cream for preventing and treating acne, it is characterised in that it is main by following mass fraction into being grouped into：Pachymaran 0.2-
0.5%th, glycyrrhizic acid 0.2-0.4%, scutelloside 0.1-0.2%, glycerine 15-20%, lecithin 5-7%, alginic acid 3-5%, palm fibre
Palmitic acid isopropyl propionate 10-15%, preservative 0.05-0.1% and water 45-70%.
2. the face cream for preventing and treating acne according to claim 1, it is characterised in that by following mass fraction into being grouped into：
Pachymaran 0.35%, glycyrrhizic acid 0.3%, scutelloside 0.15%, glycerine 18%, lecithin 6%, alginic acid 4%, palmitic acid are different
Propyl ester 13%, preservative 0.08% and water 58.12%.
3. the face cream for preventing and treating acne according to claim 1 and 2, it is characterised in that described preservative is calcium lactate.
4. the preparation method of the face cream for preventing and treating acne according to claim any one of 1-3, it is characterised in that step is：
S1：Glycerine, lecithin, alginic acid, isopropyl palmitate and water are added in emulsion tank, it is heated to 85 while stirring~
95 DEG C, stir, obtain latex A；
S2：The latex A obtained in step S1 is cooled to 50 DEG C~55 DEG C, pachymaran, glycyrrhizic acid, scutelloside, stirring is added
Uniformly, mixed liquid B is obtained；
S3：The mixed liquid B obtained in step S2 is cooled to 35 DEG C~45 DEG C, preservative is added, stirred, be down to room temperature,
Obtain final product.
5. the preparation method of the face cream for preventing and treating acne according to claim 4, it is characterised in that in step S1, S2 and S3
Mixing speed is 45-50r/min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611213678.3A CN106726689A (en) | 2016-12-24 | 2016-12-24 | It is a kind of to prevent and treat face cream of acne and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611213678.3A CN106726689A (en) | 2016-12-24 | 2016-12-24 | It is a kind of to prevent and treat face cream of acne and preparation method thereof |
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| Publication Number | Publication Date |
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| CN106726689A true CN106726689A (en) | 2017-05-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611213678.3A Pending CN106726689A (en) | 2016-12-24 | 2016-12-24 | It is a kind of to prevent and treat face cream of acne and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107496217A (en) * | 2017-09-04 | 2017-12-22 | 广州聚注通用技术研究院有限公司 | A kind of mildy wash |
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2016
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