CN106491459A - A kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof - Google Patents
A kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof Download PDFInfo
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- CN106491459A CN106491459A CN201611199905.1A CN201611199905A CN106491459A CN 106491459 A CN106491459 A CN 106491459A CN 201611199905 A CN201611199905 A CN 201611199905A CN 106491459 A CN106491459 A CN 106491459A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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Abstract
The invention belongs to cosmetics face cream field, specifically related to a kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof, face cream main component is Chinese medical extract 2 5%, glycerine 5 20%, anhydrous sorbitol laurate 1 5%, alginic acid 1 5%, isopropyl palmitate 5 15%, preservative 0.1 0.3%, water 60 80%, and wherein Chinese medical extract is to extract gained mixture with Chinese prickly ash, cordate houttuynia, Peony Root as raw material.The acne eliminating cream containing traditional Chinese medicine ingredients that the present invention is provided can not only removing acne, blackhead etc., and with good inhibiting bacteria and diminishing inflammation, refrigerant antipruritic effect, Chinese medical extract natural green therein is healthy and safe, is suitable in marketing.
Description
Technical field
The invention belongs to cosmetics face cream field, and in particular to a kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof.
Background technology
Acne and small pox are all referred to as acne.Acne is one of modal disease of Skin cosmesis, is mainly in puberty,
It is called whelk, face or acne, folliculitis.Induced factor mainly has 1, smegma vigorous；2nd, cleaning does not thoroughly cause
Hair follicle blocks；3rd, heredity；4th, stay up late caused smegma exception；5th, extreme climate increases smegma；6th, internal
Caused by disease, metabolism is abnormal.
As acne affects the face appearance of people, people once to grow acne, can directly be extruded with hand under normal circumstances, but
It is if extruding is improper to cause serious consequence, such as causes more inflammation, healing delay, residual acne print etc..Current market
On occur in that substantial amounts of product for resolving poxes, be mainly divided into following a few classes：1st, sulfur soap：Bactericidal effect is truly had to small pox inflammation, but
Too big to skin irritatin；2nd, frosted grain：Can peel off aging cutin, but the secretion of grease can be promoted, go out acne more；3rd, wine
Essence：Only concentration reaches the alcoholic solution of 60%-75% and can be only achieved the effect of sterilization, and on the market mostly only 40%, not only
Skin can be stimulated on the contrary without anti-acne effect；4th, zinc oxide：Suitable for sun-proof, protect skin sparing skin not by environmental stimuli,
But can blocked pore；5th, hormone：Hormone not only make one produce according to lazyness, Long-Time Service can cause slow poisoning, because hormone without
Hole does not enter, and can precipitate into capilary, enter blood circulation, declines passive protective physical fitness, can cause poisoning symptom.If improper make
With product for resolving poxes, anti-acne is not only unable to, can also cause more inflammation, therefore safely and efficiently the research and development of product for resolving poxes become ten
Divide important.
Notification number discloses a kind of acne-removing liquid for the Chinese patent of 103006527B, including following component：Component A：The third two
Alcohol, xanthan gum, the first solvent；B component：Two isethionic acids amidine, vitamin B6, the second solvent；Component C：Plant extraction liquid, nonyl
Diacid derivative, mother chrysanthemum dimension element, salicylic acid, ginseng extract, vitamin E, preservative.Also have in the formula that the invention is provided big
During the easy allergic component, wherein salicylic acid use of amount, local skin may occur erythema, itching, shouting pain symptom, may result in
Small pox flesh is more serious.
In order to further improve the security of product for resolving poxes, on market, there is substantial amounts of Chinese medicine product for resolving poxes, but due to
Traditional Chinese medicine ingredients extraction process is complicated, causes cost to raise, or is extracted using organic matter, cause a large amount of harmful substances remain or
Directly volatilization is slatterned active ingredient, affects product quality and performance.
The Chinese patent application of Publication No. 103784367A discloses a kind of with acne blackhead and the mitigation red blood silk of dispelling
The external skin-care composition of effect, mildy wash and preparation method thereof, and the preparation method of tcm componentses extract is disclosed, this
Bright complicated component, containing multiple artificial-synthetic materials, and Chinese medicine employs ethanol solution extraction, but due to ethanol and Chinese medicine
Active ingredient is mutually dissolved, and belongs to volatile components, thus separation be easily caused in concentration process in Chinese medicine effectively into
Point loss or the residual of alcohol component, not only can not rationally using raw material, and the stimulation skin performance of a small amount of ethanol
A part of Chinese medicine effect can be offset.
Content of the invention
In order to solve problems of the prior art, the invention provides a kind of composition green safety, anti-acne effect are aobvious
The acne eliminating cream containing traditional Chinese medicine ingredients for writing, with good inhibiting bacteria and diminishing inflammation, refrigerant antipruritic effect, and discloses Chinese medicine in component and carries
The purifying technique of thing is taken, simple and safe.
The present invention is implemented especially by technical scheme below.
A kind of acne eliminating cream containing traditional Chinese medicine ingredients, mainly by following percentage by weight into being grouped into：Chinese medical extract 2-5%,
Glycerine 5-20%, anhydrous sorbitol laurate 1-5%, alginic acid 1-5%, isopropyl palmitate 5-15%, preservative 0.1-
0.3%th, water 60-80%；
The Chinese medical extract is to extract gained mixture with Chinese prickly ash, cordate houttuynia, Peony Root as raw material.
Further, by following percentage by weight into being grouped into：Chinese medical extract 4%, glycerine 11%, anhydrous sorbitol
Laurate 2%, alginic acid 3%, isopropyl palmitate 12%, preservative 0.2%, water 67.8%.
Further, it is 2～3 that described Chinese medical extract extracts raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio：2～3：
1.
Further, it is 2.3 that described Chinese medical extract extracts raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio：2.7：
1.
Further, present invention also offers the preparation method of the composition Chinese medical extract of acne eliminating cream containing traditional Chinese medicine ingredients：
(1) Chinese prickly ash, cordate houttuynia, Peony Root are cleaned, smashes into pastel, carry out ultrasonic wave water extraction, filtered, the quality of water
It is 20-25 times of Chinese prickly ash, cordate houttuynia and Peony Root total amount, obtains filtrate A；
(2) the filtrate A distillations for step (1) being obtained, vapo(u)rizing temperature is 55-65 DEG C, and pressure is 0.9-0.95atm, collects,
Obtain distillate B；
(3) the distillate B that step (2) is collected is carried out water-oil separating, water phase return to step (1) continues to extract, and takes oil phase,
Obtain final product.
Further, present invention also offers a kind of preparation method containing traditional Chinese medicine ingredients acne eliminating cream, step is,
S1：Glycerine, anhydrous sorbitol laurate, isopropyl palmitate and water are added in emulsion tank, while stirring
85～95 DEG C, after stirring are heated to, alginic acid is added, are continued stirring 30-60min, is obtained emulsion X；
S2：Emulsion X that step S1 is obtained is cooled to 50 DEG C～55 DEG C, Chinese medical extract is added, is stirred, must mix
Liquid Y；
S3：The mixed liquor Y that step S2 is obtained is cooled to 35 DEG C～45 DEG C, adds preservative, stirs, obtain lotion Z；
S4：The lotion Z that step S3 is obtained continues to be cooled to 30-34 DEG C, obtains final product.
Chinese prickly ash：The volatile oil contained in Pericarpium Zanthoxyli fruit includes geraniol, limonene, cumic alcohol unsaturated organic acid etc..Its
Middle Chinese prickly ash has warming spleen and stomach for dispelling cold, and dehumidify desinsection, pyretic tonification of kidney yang, exempts from numbness pain relieving, and solution fish raw meat poison is applied in product for resolving poxes,
Can to acne in inflammation carry out anti-inflammatory, and to due to caused by exanthemv toxin deposition there is good sterilization to make
With.
Cordate houttuynia：There is the effects such as antibacterial, antiviral, raising immunity of organisms, diuresis.Cordate houttuynia herb contains volatile oil
0.0049%, wherein main component is decanoy acetaldehyde (rhizome volatile oil is also containing this element), methyl n nonyl ketone, lauryl aldehyde, bay
Alkene, limonene, lauro lene etc..Additionally, also containing potassium chloride, potassium sulfate, cordarine, hyperin, rutin and B- sitosterol,
Stearic acid, oleic acid, linoleic acid etc..Contain Quercetin, quercitrin, Isoquercitrin, reynoutrin and hyperin in flower, leaf, fruit.
Cordate houttuynia has clearing heat and detoxicating, resolving sputum removing pus and relieving carbuncle, inducing diuresis to remove edema is treating stranguria health-care efficacy of Denging.
Peony Root：Peony Root contains Paeoniflorin and benzoic acid, and there is Paeoniflorin expansion of blood vessels, antalgic and sedative, anti-inflammatory to resist
Ulcer, antipyretic spasmolysis, the effect of diuresis；Benzoic acid scientific name benzoic acid in its composition, antimycotic and sterilization anti-corrosion function.
Alginic acid：There are suspending, thickening, emulsification, bonding etc. to act on, act not only as thickener and the emulsification of the present invention
Agent, and alginic acid itself can treat heavy metal poisoning as absorbent, and used in the cosmetics of part, plurality of heavy metal is come
Whitening anti-wrinkling effect is provided, causes the injury of skin, therefore can have one to the heavy metal remained in cosmetics using alginic acid
Determine the adsorption effect of degree.
The Chinese medical extract added in the present invention has good bactericidal anti-inflammatory effect, and alginic acid not only increases in component
The thick viscosity for keeping acne eliminating cream, and the heavy metal component for remaining in skin surface can be absorbed.Inventive formulation is reasonable, to dispelling
Acne has good effect.
The present invention compared with prior art, with following progress：
1st, security：The experiment proved that the present invention is non-stimulated to skin safe.
2nd, anti-acne effect：Present component adopts unique Chinese herbal medicine Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root extract, containing day
So the detoxicating, relieving inflammation factor, improves skin acne state, and anti-acne effect is good.
Specific embodiment
The present invention is further illustrated by specific examples below.Composition according to the present invention belongs to conventional articles for use, wherein,
Alginic acid (CAS.9005-32-7)：Xi'an Yuhua bio tech ltd.
Embodiment 1
A kind of acne eliminating cream containing traditional Chinese medicine ingredients, composition and its percentage by weight are：Chinese medical extract 4%, glycerine 11%, dehydration
Sorbitan laurate 2%, alginic acid 3%, isopropyl palmitate 12%, preservative 0.2%, water 67.8%, described Chinese medicine
It is 2.3 that extract extracts raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio：2.7：1.
The preparation method of wherein described Chinese medical extract is：
(1) Chinese prickly ash, cordate houttuynia, Peony Root are cleaned, smashes into pastel, carry out ultrasonic wave water extraction, filtered, the quality of water
It is 22 times of Chinese prickly ash, cordate houttuynia and Peony Root total amount, obtains filtrate A；
(2) the filtrate A distillations for obtaining step (1), vapo(u)rizing temperature is 60 DEG C, and pressure is 0.93atm, collects, must distillate
Liquid B；
(3) the distillate B that step (2) is collected is carried out water-oil separating, water phase return to step (1) continues to extract, and takes oil phase,
Obtain final product.
The preparation method of described acne eliminating cream is：
S1：Glycerine, anhydrous sorbitol laurate, isopropyl palmitate and water are added in emulsion tank, while stirring
90 DEG C, after stirring are heated to, alginic acid is added, are continued stirring 45min, is obtained emulsion X；
S2：Emulsion X that step S1 is obtained is cooled to 53 DEG C, Chinese medical extract is added, is stirred, obtain mixed liquor Y；
S3：The mixed liquor Y that step S2 is obtained is cooled to 40 DEG C, adds preservative, stirs, obtain lotion Z；
S4：The lotion Z that step S3 is obtained continues to be cooled to 32 DEG C, obtains final product.
Embodiment 2
A kind of acne eliminating cream containing traditional Chinese medicine ingredients, composition and its percentage by weight are：Chinese medical extract 2%, glycerine 20%, dehydration
Sorbitan laurate 1%, alginic acid 1%, isopropyl palmitate 5%, preservative 0.1%, water 70.9%, described Chinese medicine are carried
It is 2 to take thing and extract raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio：3：1.
The preparation method of wherein described Chinese medical extract is similar to Example 1, the preparation method of described acne eliminating cream with
Embodiment 1 is similar to.
Embodiment 3
A kind of acne eliminating cream containing traditional Chinese medicine ingredients, composition and its percentage by weight are：Chinese medical extract 5%, glycerine 5%, dehydration
Sorbitan laurate 5%, alginic acid 5%, isopropyl palmitate 15%, preservative 0.5%, water 64.5%, described Chinese medicine
It is 3 that extract extracts raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio：2：1.
The preparation method of wherein described Chinese medical extract is similar to Example 1, the preparation method of described acne eliminating cream with
Embodiment 1 is similar to.
Comparative example 1
A kind of acne eliminating cream containing traditional Chinese medicine ingredients, composition and its percentage by weight are：Chinese medical extract 5%, glycerine 5%, dehydration
Sorbitan laurate 5%, alginic acid 5%, isopropyl palmitate 15%, preservative 0.3%, water 64.7%, described Chinese medicine
It is 2.3 that extract extracts raw material for Chinese prickly ash, Chinese herbaceous peony root mass ratio：1.
Comparative example 1 is to change Chinese medical extract extraction raw material not containing cordate houttuynia with the difference of embodiment 1.
The preparation method of wherein described Chinese medical extract is similar to Example 1, the preparation method of described acne eliminating cream with
Embodiment 1 is similar to.
Test example 1, safety evaluation of the present invention
Subjects：Acne eliminating cream prepared by embodiment 1-3, comparative example 1.
Tested crowd：40 people, between 15～30 years old, 20 people of female, male 20 people.
Health status：Experimenter meets experimenter's aspiration inclusion criteria without skin disease allergies.
Patch method：From qualified spot examination device, with closed patch experiment method, by tested material about 0.020ml～
In spot examination device, external application special adhesive tape is covered on experimenter back to 0.025ml drops, removes tested material, observe after 12 hours respectively
Dermoreaction in 0.5,6,12,24,48 hours after removal, according to《Cosmetics health specification》Middle dermoreaction grade scale records which
As a result.
Human skin patch result shows：40 experimenters by acne eliminating cream of the present invention (embodiment 1-3),
Reference substance (comparative example 1) patch test, observed dermoreaction at 0.5,6,12,24,48 hours, and wherein 0 skin occur bad
Reaction, illustrates to test acne eliminating cream safety used.
Test example 2, anti-acne effect is tested
Subjects：Acne eliminating cream prepared by embodiment 1-3, comparative example 1.
Tested crowd：80 people, between 15～30 years old, 40 people of female, male 40 people, random point 4 groups.
Skin health：Small pox flesh caused by various factors, causes reason：1st, puberty：Skin oil and fat secretion is vigorous；
2nd, heredity；3rd, diet is bad；4th, pressure is stayed up late greatly, often, contacts oil smoke；5th, endocrinopathy；6th, oily skin.
Test method：After basic skin care, appropriate this product is smeared, consumption can be increased in acne position, daily sooner or later once,
Per group is only used a kind of acne eliminating cream.
Effective evaluation standard：
(1) dispel completely：After smearing 2 months, all acnes disappear.
(2) effective：After smearing 2 months, acne disappears substantially.
(3) effectively：After smearing, 4 months acnes disappear substantially.
(4) invalid：All acne symptoms are without significant change.
As a result as shown in table 1 below：
The acne eliminating cream anti-acne effect that 1 embodiment 1-3 of table is prepared with comparative example 1
| Group | Embodiment 1 | Embodiment 2 | Embodiment 3 | Comparative example 1 |
| Dispel completely | 14 | 12 | 13 | 9 |
| Effective | 5 | 6 | 5 | 6 |
| Effectively | 1 | 2 | 2 | 4 |
| Invalid | 0 | 0 | 0 | 1 |
From table 1 it follows that embodiment 1-3 is relative to comparative example 1, anti-acne effect becomes apparent from, and dispels completely people
Number is more, illustrates that the present invention has good anti-acne effect, and safety does not stimulate, with good market prospects.
Test example 3, investigation on probation
Subjects：Acne eliminating cream prepared by embodiment 1-3, comparative example 1.
Tested crowd：40 people, between 15～30 years old, 20 people of female, male 20 people, random point 4 groups.
Skin health：Face has acne or blackhead.
Test method：After basic skin care, appropriate this product is smeared, daily sooner or later once, continuous using 2 months.Per group only
A kind of acne eliminating cream is used, other product for resolving poxes are not used, is tried out and is evaluated as shown in table 2.
The acne eliminating cream trial effect that 2 embodiment 1-3 of table is prepared with comparative example 1
From Table 2, it can be seen that comparing the anti-acne of the preparation of comparative example 1 using acne eliminating cream prepared by embodiment of the present invention 1-3
The composition of Chinese medical extract more preferably, is simply made corresponding adjustment in comparative example 1 by white effect, and its effect changes, explanation
Inventive formulation combination arbitrarily can not change, and further illustrate compatibility of the present invention rationally, have preferable anti-acne, pore cleanser and net skin
Effect.
The principle and its effect of above-described embodiment only illustrative present invention, of the invention not for limiting.Any ripe
The personage for knowing this technology all can carry out modifications and changes to above-described embodiment under the spirit and the scope without prejudice to the present invention.Cause
This, those of ordinary skill in the art is complete with institute under technological thought without departing from disclosed spirit such as
Into all equivalent modifications or change, should by the present invention claim be covered.
Claims (6)
1. a kind of acne eliminating cream containing traditional Chinese medicine ingredients, it is characterised in that mainly by following percentage by weight into being grouped into：Traditional Chinese medicine extraction
Thing 2-5%, glycerine 5-20%, anhydrous sorbitol laurate 1-5%, alginic acid 1-5%, isopropyl palmitate 5-15%, anti-
Rotten agent 0.1-0.3%, water 60-80%；
The Chinese medical extract is to extract gained mixture with Chinese prickly ash, cordate houttuynia, Peony Root as raw material.
2. acne eliminating cream containing traditional Chinese medicine ingredients according to claim 1, it is characterised in that by following percentage by weight into packet
Into：Chinese medical extract 4%, glycerine 11%, anhydrous sorbitol laurate 2%, alginic acid 3%, isopropyl palmitate 12%, anti-
Rotten agent 0.2%, water 67.8%.
3. acne eliminating cream containing traditional Chinese medicine ingredients according to claim 1 and 2, it is characterised in that described Chinese medical extract is extracted
Raw material Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio are 2～3：2～3：1.
4. acne eliminating cream containing traditional Chinese medicine ingredients according to claim 3, it is characterised in that described Chinese medical extract extracts raw material
Chinese prickly ash, cordate houttuynia, Chinese herbaceous peony root mass ratio are 2.3：2.7：1.
5. acne eliminating cream containing traditional Chinese medicine ingredients according to claim 1 and 2, it is characterised in that the system of described Chinese medical extract
Preparation Method is：
(1) Chinese prickly ash, cordate houttuynia, Peony Root are cleaned, smashes into pastel, carry out ultrasonic wave water extraction, filtered, the quality of water is colored
20-25 times of green pepper, cordate houttuynia and Peony Root total amount, obtains filtrate A；
(2) the filtrate A distillations for obtaining step (1), vapo(u)rizing temperature is 55-65 DEG C, and pressure is 0.9-0.95atm, collects, must evaporate
Go out liquid B；
(3) the distillate B that step (2) is collected is carried out water-oil separating, water phase return to step (1) continues to extract, and takes oil phase, i.e.,
?.
6. the preparation method containing traditional Chinese medicine ingredients acne eliminating cream according to any one of claim 1-5, it is characterised in that step
For,
S1：Glycerine, anhydrous sorbitol laurate, isopropyl palmitate and water are added in emulsion tank, are heated while stirring
To 85～95 DEG C, after stirring, alginic acid is added, continue stirring 30-60min, obtain emulsion X；
S2：Emulsion X that step S1 is obtained is cooled to 50 DEG C～55 DEG C, Chinese medical extract is added, is stirred, obtain mixed liquor Y；
S3：The mixed liquor Y that step S2 is obtained is cooled to 35 DEG C～45 DEG C, adds preservative, stirs, obtain lotion Z；
S4：The lotion Z that step S3 is obtained continues to be cooled to 30-34 DEG C, obtains final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611199905.1A CN106491459A (en) | 2016-12-22 | 2016-12-22 | A kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611199905.1A CN106491459A (en) | 2016-12-22 | 2016-12-22 | A kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106491459A true CN106491459A (en) | 2017-03-15 |
Family
ID=58335128
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611199905.1A Withdrawn CN106491459A (en) | 2016-12-22 | 2016-12-22 | A kind of acne eliminating cream containing traditional Chinese medicine ingredients and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116712382A (en) * | 2023-07-25 | 2023-09-08 | 广州市百集生物科技有限公司 | Acne-removing essence and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057191A (en) * | 1991-06-29 | 1991-12-25 | 河南医科大学 | Nourishing skin cream |
| CN104434609A (en) * | 2013-09-13 | 2015-03-25 | 广东轻工职业技术学院 | Compound traditional Chinese medicine extract with acne removing function and application thereof in cosmetics |
| CN105796462A (en) * | 2016-03-25 | 2016-07-27 | 无锡简玺生物科技有限公司 | Composition used for cleaning skin and preparation method thereof |
-
2016
- 2016-12-22 CN CN201611199905.1A patent/CN106491459A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1057191A (en) * | 1991-06-29 | 1991-12-25 | 河南医科大学 | Nourishing skin cream |
| CN104434609A (en) * | 2013-09-13 | 2015-03-25 | 广东轻工职业技术学院 | Compound traditional Chinese medicine extract with acne removing function and application thereof in cosmetics |
| CN105796462A (en) * | 2016-03-25 | 2016-07-27 | 无锡简玺生物科技有限公司 | Composition used for cleaning skin and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116712382A (en) * | 2023-07-25 | 2023-09-08 | 广州市百集生物科技有限公司 | Acne-removing essence and preparation method thereof |
| CN116712382B (en) * | 2023-07-25 | 2024-04-16 | 广州市百集生物科技有限公司 | Acne-removing essence and preparation method thereof |
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Application publication date: 20170315 |