CN103432024A - Cosmetic composition with function of removing acne - Google Patents
Cosmetic composition with function of removing acne Download PDFInfo
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Abstract
The invention discloses a cosmetic composition with function of removing acne. The active components of the cosmetic composition is prepared from the following natural herbaceous plants by weight ratio: 3-50 parts of scutellariabaicalensis, 3-50 parts of wild chrysanthemum flower, 3-50 parts of honeysuckle flower, 3-50 parts of cape jasmine, 3-50 parts of cortex moutan and 3-50 parts of radix paeoniaerubra. The active components of the cosmetic composition have bacteriostasis and anti-inflammation effects on acne, wherein acne usually also means whelks, pimples or comedones, and belongs to a chronic inflammation disease of skin hair follicle sebaceous gland. The cosmetic composition is characterized by being prepared by taking the natural herbaceous plants as the main raw materials, and through function tests, the results prove that the cosmetic composition has efficacies of bacteriostasis and inflammation resistance.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of cosmetic composition with acne-removal function.
Background technology
Pox is being commonly called as of acne, claim again " comedo ", " skin sore " or " acne ", to betide pilosebaceous a kind of chronic inflammation disease, be mainly manifested in clinically face, chest and back and acne, pimple, pustule, cyst and tuberosity occur, the formed cicatrix had, have a strong impact on people's appearance, to normal person's the generation material impacts such as employment, social activity and marriage and childbirth.Think that at present morbidity and androgen levels, sebum secretion increase, hair follicle conduit hyperkeratosis, the propionibacterium acnes of acne infect relevant.
Along with the raising of people's living standard, rhythm of life is accelerated, the impacts such as life stress increasing and environmental pollution, incidence of acne is in rising trend, and age of onset also widens, and the course of disease extends, mostly be Persistent Acne of Different, have a strong impact on people's physical and mental health and quality of life.Propionibacterium acnes is gram-negative facultatively anacrobic rod, main field planting, at human skin pilosebaceous unit folliculus, is the opportunistic pathogenic bacterium, and it can adapt to various complicated, and make its cell wall avoid the degraded of neutrophilic granulocyte and macrophage, can also suppressor T cell activate.Its special physio-biochemical characteristics determine the mechanism of causing a disease that it is complicated, and and then cause the various clinical diseases such as acne.Existing research shows, propionibacterium acnes stimulates keratinocyte to produce the proinflammatory cytokine as IL-1a, IL-1 β, IL-8, TNF-α, these cytokines can promote other release of cytokines again, therefore, propionibacterium acnes can be set up a positive feedback loop by these cytokines and maintain, promotes inflammatory process.
The traditional Chinese medical science thinks that primary disease is " heat in blood stasis loose " and cause.This disease is mainly in person between twenty and fifty, and preponderance of YANG QI inside accumulates heat in blood, and the gas fire is partially prosperous, causes the blood that burns and becomes the stasis of blood, strongly fragrant fighting in skin, venation as suffering from.Acne treatment is advisable with clearing away heat and cooling blood, blood stasis-eliminating and stagnation-dissipating.
Summary of the invention
The purpose of this invention is to provide a kind of cosmetic composition with acne-removal function, the active component of this cosmetic composition be take the natural herb plant as the primary raw material extraction, and macroporous resin separation and purification preparation, have antibacterial and effect antiinflammatory.
A kind of cosmetic composition with variola function provided by the invention, the active component of this cosmetic composition is prepared by the natural herb plant material of following weight parts proportioning: Radix Scutellariae 3～50, Flos Chrysanthemi Indici 3～50, Flos Lonicerae 3～50, Fructus Gardeniae 3～50, Cortex Moutan 3～50, Radix Paeoniae Rubra 3～50.
Preferred weight part proportioning of the natural herb plant material of the active component of preparation cosmetic composition of the present invention is: Radix Scutellariae 3～30, Flos Chrysanthemi Indici 3～30, Flos Lonicerae 3～30, Fructus Gardeniae 3～30, Cortex Moutan 3～30, Radix Paeoniae Rubra 3～30.
Optimum weight part proportioning of the natural herb plant material of the active component of preparation cosmetic composition of the present invention is: Radix Scutellariae 4, Flos Chrysanthemi Indici 2, Flos Lonicerae 3, Fructus Gardeniae 2, Cortex Moutan 4, Radix Paeoniae Rubra 3.
In the composition of cosmetic composition of the present invention, the relative content of the active component of cosmetic composition is 0.1～10.00%, all the other substrate commonly used that are the cosmetics exterior-applied formulation and deionized water or purified water or distilled water.By common process, can be made into anti-acne facial cleanser, anti-acne Cleansing Foam, the anti-acne cosmetics exterior-applied formulations such as frost, Whelk-eliminating paste, acne eliminating cream, anti-acne emulsion, acne removing water, Deacne pack, anti-acne gel or anti-acne soap of washing one's face.
The natural herb plant material of the active component of preparation cosmetic composition of the present invention has following effect and characteristics:
The dry root that Radix Scutellariae is labiate Radix Scutellariae Scutellaria baicalensis Georgi., have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Be mainly used in the diseases such as pyogenic infection such as lung-heat, hemoptysis, enteritis, dysentery, jaundice, hypertension and upper respiratory tract infection, urinary system infection.Main effective ingredient in Radix Scutellariae is flavone compound, as baicalin<Baicalin), noroxylin (Baicalein), wogonin (Wogonin), wogonoside (Wogonoside), neobaicalein I, II (Neobaicalein work, II) etc.Pharmacological research proves, and that baicalin has is antibacterial, heat clearing away, blood pressure lowering, calmness, diuresis, function of gallbladder promoting, antiinflammatory, antiallergic action isoreactivity.
Flos Chrysanthemi Indici is the dry capitulum of feverfew Herba Dendranthematis indici (Chrysanthemum indicum L.), in China, most area extensively distributes, effect with dispelling wind, heat clearing away, improving eyesight, removing toxic substances, the diseases such as primary treatment headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.The research in recent years discovery, the chemical composition of Flos Chrysanthemi Indici is main: terpenoid and volatile oil, comprise monoterpene, sesquiterpene, dimerization sesquiterpene, triterpene and containing oxygen derivative thereof etc., wherein major part is present in volatile oil; Flavone compound, comprise the flavone compounds such as wooden slippers flavonoid glycoside, acacetin glycosides, luteolin, apiolin; It is main pharmacodynamics part wherein.Pharmaceutical research shows that Flos Chrysanthemi Indici extract has anti-bacteria and anti-virus, antiinflammatory and immunity, protection cardiovascular system, antitumor, protects the liver and the pharmacological actions such as neuroprotective.Be mainly used in clinically anti-inflammation, heat-clearing and toxic substances removing.
Flos Lonicerae is the alabastrum that the Caprifoliaceae perennial evergreen is wound around bejuco Radix Ophiopogonis Lonicera japonica Thunb., has another name called Flos Lonicerae, Flos Lonicerae, and in China, except northwest, northeast, all there is distribution other each provinces and regions.Traditional Chinese Medicine thinks to have the effect of heat-clearing and toxic substances removing, wind-heat dissipating by Flos Lonicerae sweet in the mouth cold in nature, for carbuncle furuncle, sore throat, erysipelas, warm blood fulminant dysentery, anemopyretic cold, epidemic febrile disease heating.Its chemical composition is mainly chlorogenic acid, isochlorogenic acid, aromatic alcohol, luteolin, Flos Lonicerae saponin and flavone compound.Studies confirm that at present Flos Lonicerae has the effects such as broad-spectrum antiseptic, antiviral, antipyretic and anti-inflammatory, function of gallbladder promoting protect the liver, blood fat reducing.
The fruit that Fructus Gardeniae is Maguireothamnus speciosus Fructus Gardeniae Gardenia jasminoides Ellis..Effect with pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Be used for the treatment of calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache.Its main component is flavone compound, as gardenin (Gardenin), and triterpenoid compound, crocin (Crocin), crocetin (Crocetin) and α-Stigma Croci glycoside unit (α-Crocetin); Also containing iridoid glycosides gardenoside (Jasminoidin), gardenoside (Gardenoside), geniposide (geniposide, Geniposide), genipin gentiobioside (Genipingentiobioside), Fructus Gardeniae ketone glycoside (Gardoside), Herba Paederiae time glycoside methyl ester (Scandoside methyl ester), de-acetyl rubichloric acid. acid methyl ester (Deacetylasperulosidic acid methyl ester), geniposidic acid (Geniposidic acid) etc.
The dry root bark that Cortex Moutan is ranunculaceae peony Paeonia suffruticosa Andr..Have clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling, for damp and hot speckle, hematemesis and epistaxis, night fever abating at dawn, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, traumatic pain etc.Its main effective ingredient comprises paeonol, Cortex Moutan phenolic glycoside, the former glycosides of paeonol, the new glycosides of paeonol, peoniflorin etc.
The dry root that Radix Paeoniae Rubra is cohosh Radix Paeoniae Paeonia lactiflora Pall. or river Radix Paeoniae Rubra Paeonia veitchii Lynch.Nature and flavor are bitter, be slightly cold, and return Liver Channel, have clearing away heat and cooling blood, eliminating stasis to stop pain effect.Mainly contain paeoniflorin, Albiflorin, oxypaeoniflorin, benzoylpaeoniflorin, the lucky ketone of Radix Paeoniae, Lactiflorin., daucosterol in Radix Paeoniae Rubra, also contain d-catechin, gallotannin, benzoic acid, volatile oil, fatty oil, resin, sugar, starch, lymphatic temperament, protein etc.Radix Paeoniae Rubra is mainly used in treating the diseases such as maculae caused by violent heat pathogen, haematemesis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, the swollen skin infection of pain, traumatic injury, amenorrhea, dysmenorrhea clinically in recent years.Modern study shows that Radix Paeoniae Rubra all has inhibitory action to a certain degree to staphylococcus aureus, escherichia coli, shigella and Bacillus typhi.
The active component of cosmetic composition of the present invention refers to from natural herb plant material Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra by mixed extraction (water extraction or alcohol extraction), extracting solution prepares through the macroporous resin separation and purification, in this active component general flavone content more than 17% or total phenol content more than 20% or content of baicalin more than 20%.
In the natural herb plant material of the active component of preparation cosmetic composition of the present invention, the Radix Scutellariae heat-clearing and toxic substances removing, the fire of clear part of the body cavity above the diaphragm housing the heart and lungs cardiopulmonary is except damp and hot; Radix Paeoniae Rubra, Cortex Moutan, Radix Scutellariae share eliminating fire and detoxication; Flos Lonicerae heat-clearing and toxic substances removing, the removing heat from blood rash that disappears; Flos Lonicerae, Cortex Moutan, Radix Paeoniae Rubra share clearing away heat and cooling blood, removing toxic substances softening the hard mass, Radix Paeoniae Rubra blood circulation promoting and blood stasis dispelling; Flos Chrysanthemi Indici waits more serious disease for the swollen suppuration of carbuncle furuncle.The all medicine synergistic application of Qinghuo Jiedu, promote tissue repair and antibacterial and bacteriostasis, thereby reach the effect of removing acne.
The accompanying drawing explanation
Fig. 1 is the impact that combined extracts of the present invention discharges foot swelling mice IL-1a.* P<0.05, * * P<0.01, with the blank group relatively; #P<0.05, ##P<0.01, compare with model group.
Fig. 2 is the impact that combined extracts of the present invention discharges foot swelling mice PGE2.* P<0.05, * * P<0.01, with model group relatively; #P<0.05, ##P<0.01, compare with the solvent group.
Below by the specific embodiment and function assessment result of study, the invention will be further described.
The specific embodiment
The present invention will be described below to enumerate a part of specific embodiment, is necessary to be pointed out that at this following specific embodiment, only for the invention will be further described, does not represent limiting the scope of the invention.Some nonessential modifications that other people make according to the present invention and adjustment still belong to protection scope of the present invention.
Embodiment 1
Get Radix Scutellariae 500g, Flos Chrysanthemi Indici 300g, Flos Lonicerae 500g, Fructus Gardeniae 300g, Cortex Moutan 500g, Radix Paeoniae Rubra 400g.
Above-mentioned raw materials is followed these steps to be prepared into the anti-acne gel:
Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, after the decocting in water extraction is concentrated, are added to the ethanol precipitation, standing, filter, filtrate recycling ethanol, to nothing alcohol flavor, obtains the Chinese herbal medicine concentrated solution.By macroporous resin column on concentrated solution, washing, ethanol elution, collect eluent, and eluent reclaims ethanol, and concentrated, drying, obtain the chocolate brown powder combined extracts.
The anti-acne gel:
The component and the relative content thereof that form above-mentioned anti-acne gel products are:
The preparation method of above-mentioned anti-acne gel products, comprise the following steps:
(1) butanediol, deionized water are mixed, stir and make its dissolving;
(2) add acrylic acid dimethyl taurine ammonium/VP copolymer, the limit edged stirs, and obtains clear gel substrate after stirring;
(3) get combined extracts, add propylene glycol, stir and make its dissolving, make solution;
(4) by combined extracts solution and gel-type vehicle mixing and stirring, deionized water adds to full dose;
(5) regulate between pH value to 5.5～6.5;
(6) above-mentioned gel is tested, qualified after, then carry out fill and obtain anti-acne gel skin care item.
Anti-acne gel of the present invention is made by the Chinese herbal medicine active component, and the natural gentleness of raw material is little to the zest of skin, and active component used, promotes tissue repair and has antibacterial and bacteriostasis, thereby reaching the effect of removing acne.
Embodiment 2
Get Radix Scutellariae 150g, Flos Chrysanthemi Indici 120g, Flos Lonicerae 120g, Fructus Gardeniae 120g, Cortex Moutan 150g, Radix Paeoniae Rubra 120g.
Above-mentioned raw materials is followed these steps to be prepared into the anti-acne facial milk cleanser:
Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, after the decocting in water extraction is concentrated, are added to the ethanol precipitation, standing, filter, filtrate recycling ethanol, to nothing alcohol flavor, obtains the Chinese herbal medicine concentrated solution.By macroporous resin column on concentrated solution, washing, ethanol elution, collect eluent, and eluent reclaims ethanol, and concentrated, drying, obtain the chocolate brown powder combined extracts.
The anti-acne facial milk cleanser:
The component and the relative content thereof that form above-mentioned anti-acne facial milk cleanser are:
The preparation method of above-mentioned anti-acne facial milk cleanser is: get lauric acid, myristic acid, Palmic acid, stearic acid mixing, be heated with stirring to 80～90 ℃ and make its dissolving; Potassium hydroxide dilutes with deionized water, adds in above-mentioned solution heating (being controlled at 80～90 ℃) stirring and dissolving; Glycerol, acrylic acid (ester) analog copolymer are mixed with deionized water, add in above-mentioned solution stirring and dissolving.Combined extracts and mixed with propylene glycol are dissolved, and add while being down to below 45 ℃ until solution is cooling, and add surplus stock, and stirring and dissolving is even.Detect pH value, viscosity, microorganism before discharging, qualifiedly get final product fill.The facial milk cleanser pH value of regulating out is 8.0～9.0, viscosity 7,000～20,000cPa.s (25 ℃).
Embodiment 3
Get Radix Scutellariae 100g, Flos Chrysanthemi Indici 100g, Flos Lonicerae 100g, Fructus Gardeniae 100g, Cortex Moutan 120g, Radix Paeoniae Rubra 100g.
Above-mentioned raw materials is followed these steps to be prepared into acne eliminating cream:
Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, after the decocting in water extraction is concentrated, are added to the ethanol precipitation, standing, filter, filtrate recycling ethanol, to nothing alcohol flavor, obtains the Chinese herbal medicine concentrated solution.By macroporous resin column on concentrated solution, washing, ethanol elution, collect eluent, and eluent reclaims ethanol, and concentrated, drying, obtain the chocolate brown powder combined extracts.
Acne eliminating cream:
The component and the relative content thereof that form above-mentioned acne eliminating cream are:
Oil phase:
Water:
The preparation method of above-mentioned acne eliminating cream is: after oil phase, water are heated to respectively to 80 ℃, the equal prime number minute of biphase mixing, stir cooling, cools to 45 ℃ and add combined extracts, essence, antiseptic, stirs, and 35 ℃ become the uniform mastic of faint yellow exquisiteness.
Embodiment 4
Get Radix Scutellariae 80g, Flos Chrysanthemi Indici 40g, Flos Lonicerae 60g, Fructus Gardeniae 40g, Cortex Moutan 80g, Radix Paeoniae Rubra 60g.
Above-mentioned raw materials is followed these steps to be prepared into Deacne pack:
Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, after the decocting in water extraction is concentrated, are added to the ethanol precipitation, standing, filter, filtrate recycling ethanol, to nothing alcohol flavor, obtains the Chinese herbal medicine concentrated solution.By macroporous resin column on concentrated solution, washing, ethanol elution, collect eluent, and eluent reclaims ethanol, and concentrated, drying, obtain the chocolate brown powder combined extracts.
Deacne pack:
The component and the relative content thereof that form above-mentioned Deacne pack are:
The preparation method of above-mentioned Deacne pack product, comprise the following steps:
(1) butanediol, glycerol, deionized water are mixed, stir and make its dissolving;
(2) add hydroxyethyl-cellulose, the limit edged stirs, and is heated to 80 ℃ of dissolvings;
(3) add Jojoba wax PEG-120 esters, EDTA-2Na, stirring and dissolving;
(4) be cooled to 40 ℃;
(3) get combined extracts, add propylene glycol, stir and make its dissolving, make solution;
(4) by combined extracts solution and above substrate mixing and stirring, and do not add composition;
(5) regulate between pH value to 5.5～6.5;
(6) above-mentioned base material is tested, qualified after, then carry out fill and obtain Deacne pack.
Get Radix Scutellariae 80g, Flos Chrysanthemi Indici 40g, Flos Lonicerae 60g, Fructus Gardeniae 40g, Cortex Moutan 80g, Radix Paeoniae Rubra 60g.
Above-mentioned raw materials is followed these steps to be prepared into acne removing perfumed soap:
Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra, after the decocting in water extraction is concentrated, are added to the ethanol precipitation, standing, filter, filtrate recycling ethanol, to nothing alcohol flavor, obtains the Chinese herbal medicine concentrated solution.By macroporous resin column on concentrated solution, washing, ethanol elution, collect eluent, and eluent reclaims ethanol, and concentrated, drying, obtain the chocolate brown powder combined extracts.
Acne removing perfumed soap:
The component and the relative content thereof that form above-mentioned acne removing perfumed soap are:
The preparation method of above-mentioned acne removing perfumed soap is: all raw material mix and blends, and refining the grinding, the vacuum press slivering, cut and print rear packing and get final product.
Function assessment research
The present invention is to provide a kind of cosmetic composition with acne-removal function, for proving it, have acne-dispelling function, the applicant uses the combined extracts that embodiment 1 makes to carry out the function assessment test, and result of the test is as follows:
Through South-Center University For Nationalities, test of pesticide effectiveness research shows, combined extracts of the present invention has obvious antiphlogistic effects and suppresses the effect of 5α-reductase.
1, mice caused by dimethylbenzene xylene ear swelling test: the experiment first day, with the outside, be coated with relative medicine to respectively the wide inboard of every mouse right ear, and dry up with hair dryer cold wind.Second day is with the first day administration, and in second night to the mice overnight fasting.The 3rd day 30min after administration, in the mouse right ear exterior feature, the outside evenly is coated with 40ul caused by dimethylbenzene xylene inflammation.Cause scorching rear 30min rechallenge.Cause scorching rear 60min, use the etherization mice, measure the thickness at the same position of ear, mice left and right with the spiral micrometer, using two ear thickness differences as swelling.Cause scorching rear 120min, mice is put to death in the cervical vertebra dislocation, uses the 6mm card punch, and the auricle of preparation left and right ear same area, put on analytical balance and weigh immediately.It is auricle swelling degree that auris dextra sheet weight deducts left auricle weight, with the t check, carries out statistical procedures.
Experimental result shows, high, medium and low three the dosage groups of combined extracts of the present invention have all shown significant antiphlogistic effects
The impact of table 1. combined extracts on auricle edema due to mice dimethylbenzene
* P<0.05, * *<0.01, with model group relatively.
2, pedal swelling experiment after 1% carrageenin induced mice: the experiment first day, be coated with relative medicine to respectively every right back foot of mice, and dry up with hair dryer cold wind, the same first day of second day administration, and in second night to the mice overnight fasting.Within the 3rd day, before administration, with capacity measurer, first measure its right back sufficient volume twice, getting its meansigma methods is basic volumetric values.30min after administration, 1% carrageenin in the right back vola of mice subcutaneous injection 0.02ml causes inflammation, cause scorching rear 30min, 60min, 120min, 180min, again measure respectively its right back sufficient volume, consequently scorching rear volume as swelling, carries out statistical procedures with the t check with the difference that causes scorching front basic volumetric values.Cause scorching rear 180min, mice is put to death in the cervical vertebra dislocation, cuts two metapedes of mice, puts on analytical balance and weighs immediately.It is paw swelling that right back heavy sensation in the foot amount deducts left back heavy sensation in the foot amount, with the t check, carries out statistical procedures.Experimental result shows: combined extracts high dose group of the present invention 2h after modeling can alleviate the pedal swelling due to carrageenin.
The impact of table 2. combined extracts on 1% carrageenin induced mice pedal swelling
3, the impact of combined extracts on mice pedal swelling position inflammatory factor IL-1a and PGE2 release: model group mice swelling tissue occurs that significant IL-1a and PGE2 discharge, and the release of hydrocortisone and medicine treated animal IL-1a and PGE2 all significantly descends.The slight decline of PGE2 has also appearred in the solvent group simultaneously, but compares with the administration group, still has significant difference, sees Fig. 1 and Fig. 2.
4, the inhibitory action of combined extracts to 5 alpha-reductase activity: the time changing curve of measuring the characteristic absorption wavelength OD value of NADPH by ultraviolet-visible spectrophotometer, convert out the lowering of concentration speed in 10min as zymetology reaction substrate NADPH according to curve, further obtain enzymatic activity, after convert out the Michaelis constant K of steroidal 5α-reductase by Lineweaver-Burk graphing method reciprocal
mvalue, detect the inhibitory action of combined extracts to the steroidal 5α-reductase.Experimental result shows, combined extracts is 6 μ molL in testosterone concentration
-1above have stronger inhibitory action to the steroidal 5α-reductase.
5α-reductase vigor under the different testosterone concentration of table 3
Claims (6)
1. the cosmetic composition with acne-removal function, it is characterized in that, the active component of this cosmetic composition is prepared by the natural herb plant material of following weight parts proportioning: Radix Scutellariae 3～50, Flos Chrysanthemi Indici 3～50, Flos Lonicerae 3～50, Fructus Gardeniae 3～50, Cortex Moutan 3～50, Radix Paeoniae Rubra 3～50.
2. the cosmetic composition with acne-removal function according to claim 1, it is characterized in that, the weight portion proportioning of described natural herb plant material is: Radix Scutellariae 3～30, Flos Chrysanthemi Indici 3～30, Flos Lonicerae 3～30, Fructus Gardeniae 3～30, Cortex Moutan 3～30, Radix Paeoniae Rubra 3～30.
3. the cosmetic composition with acne-removal function according to claim 1, is characterized in that, the weight portion proportioning of described natural herb plant material is: Radix Scutellariae 4, Flos Chrysanthemi Indici 2, Flos Lonicerae 3, Fructus Gardeniae 2, Cortex Moutan 4, Radix Paeoniae Rubra 3.
4. according to claim 1 or the 2 or 3 described cosmetic compositions with acne-removal function, it is characterized in that, the active component of this cosmetic composition refers to from natural herb plant material Radix Scutellariae, Flos Chrysanthemi Indici, Flos Lonicerae, Fructus Gardeniae, Cortex Moutan, Radix Paeoniae Rubra and passes through mixed extraction, the combined extracts that extracting solution prepares through the macroporous resin separation and purification, in this active component general flavone content more than 17% or total phenol content more than 20% or content of baicalin more than 20%.
5. the cosmetic composition with acne-removal function according to claim 4, it is characterized in that, in the composition of this cosmetic composition, the relative content of the active component of cosmetic composition is 0.1～10.00%, all the other substrate commonly used that are the cosmetics exterior-applied formulation and deionized water or purified water or distilled water.
6. the cosmetic composition with acne-removal function according to claim 5, it is characterized in that, described cosmetics exterior-applied formulation is anti-acne facial cleanser, anti-acne Cleansing Foam, anti-acne wash one's face frost, Whelk-eliminating paste, acne eliminating cream, anti-acne emulsion, acne removing water, Deacne pack, anti-acne gel or anti-acne soap.
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| CN105078829A (en) * | 2015-08-28 | 2015-11-25 | 青岛海之源智能技术有限公司 | Chinese medicinal acne-removing face cream and preparation method thereof |
| CN105662994A (en) * | 2016-01-18 | 2016-06-15 | 罗美香 | Traditional Chinese medicine based oil-control anti-acne moisturizer |
| CN105662968A (en) * | 2016-03-02 | 2016-06-15 | 广州千百度化妆品有限公司 | Face cleanser for removing acne marks |
| CN105662962A (en) * | 2016-03-01 | 2016-06-15 | 苏州艾缇克药物化学有限公司 | Anti-acne cream based on high-purity herbal extract, and preparation method of anti-acne cream |
| CN105287302B (en) * | 2015-11-25 | 2017-01-18 | 广州澳鑫生物科技有限公司 | Acne removing facial cleanser |
| CN106726689A (en) * | 2016-12-24 | 2017-05-31 | 叶宗瑞 | It is a kind of to prevent and treat face cream of acne and preparation method thereof |
| CN107496279A (en) * | 2017-10-24 | 2017-12-22 | 浙江海洋大学 | A kind of natural nano Deacne pack and its preparation |
| CN108456597A (en) * | 2017-10-24 | 2018-08-28 | 浙江康鸿生物科技有限公司 | A kind of preparation method of cape jasmine antiphlogistic craft cold process soap |
| CN108635315A (en) * | 2018-05-17 | 2018-10-12 | 东莞市卫花生物科技有限公司 | A kind of anti-acne antiseptic |
| CN108704040A (en) * | 2018-08-23 | 2018-10-26 | 山东效强美容服务有限公司 | A kind of Chinese medicine composition and its application |
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| CN108704040B (en) * | 2018-08-23 | 2021-09-17 | 山东效强美容服务有限公司 | Traditional Chinese medicine composition and application thereof |
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