CN105662994A - Traditional Chinese medicine based oil-control anti-acne moisturizer - Google Patents
Traditional Chinese medicine based oil-control anti-acne moisturizer Download PDFInfo
- Publication number
- CN105662994A CN105662994A CN201610040007.5A CN201610040007A CN105662994A CN 105662994 A CN105662994 A CN 105662994A CN 201610040007 A CN201610040007 A CN 201610040007A CN 105662994 A CN105662994 A CN 105662994A
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- parts
- chinese medicine
- radix
- pox
- control oil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
- A61K2800/72—Hypo-allergenic
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the field of cosmetics, in particular to a traditional Chinese medicine based oil-control anti-acne moisturizer.The traditional Chinese medicine based oil-control anti-acne moisturizer is characterized in that its traditional Chinese medicine formula comprises, by weight, 10-40 parts of Radix Trichosanthis, 10-30 parts of Flos Lonicerae, 5-25 parts of Radix Puerariae , 5-25 parts of Fructus Gardeniae, 5-15 parts of Radix Scutellariae, 1-10 parts of Cornu Bubali and 1-10 parts of Concha Margaritifera.Active ingredient of the Chinese medicinal herbs is extracted to prepare the traditional Chinese medicine based oil-control anti-acne moisturizer capable of suppressing acne and substituting for general moisturizer in use.
Description
[technical field]
The present invention relates to cosmetic field, be specifically related to a kind of generation suppressing comedo can substitute for simultaneously common moisture retention water use Chinese medicine control oil press down pox moisture retention water.
[background technology]
Comedo is that the pilosebaceous unit chronic inflammatory skin that many factors causes is sick. Wherein fat secretion is vigorous is one of them major incentive. The book several times of the long pox likelihood ratio normal person of crowd of oily skin, and long pox frequency also exceeds several times, is the important factor bringing out comedo. It is common in the youngster of adolescence. Oily skin shows that fat secretion is vigorous, forehead, the wing of nose have glossy, and majority's colour of skin is partially deep, corse sweat pore, it might even be possible to orange peel appearance occur, it is easy to adhering dust and dirt, brings out infection and the acne etc. of skin.
Reducing fat secretion, the mode of control oil suppresses comedo to be a kind of method of practicable, inducement is controlled on source, is a kind of active mode to skin care.
The principle of the invention is by enhancing metabolism, and promotes fat metabolic, reduces the fat secretion of cell, and the mode of control oil suppresses comedo.
The concrete effect of the present invention is embodied in, and the collaborative moisture of various active composition penetrates into the horny layer of epidermis, makes skin become soft, the water content of skin rises, and cutaneous permeability strengthens, and effective ingredient can act on subcutaneous deep cell, reduce fat secretion, from the minimizing accomplishing fat secretion amount endogenous; Accelerate the fat metabolic of excess surface simultaneously, form double effects, synergism, make skin get well. The present invention has replenishing water and preserving moisture effect simultaneously, has the oily skin class people team control oil present invention to replace daily moisture retention water, plays the effect killed two birds with one stone.
Like product is fewer on the market, and product is concentrated mainly on the treatment after small pox grows up to. As: Whelk-eliminating paste, acne eliminating cream, etc. Control oil of the present invention suppresses the generation of comedo to have moistening effect concurrently simultaneously, it is possible to replacing common moisture retention water to use, safety non-toxic, market prospect is huge.
[summary of the invention]
For problems of the prior art the invention provides a kind of generation suppressing comedo can substitute for simultaneously common moisture retention water use Chinese medicine control oil press down pox moisture retention water.
The present invention adopts the active ingredients of Chinese medicine extract to be primary raw material, add without any chemicals, to skin safe without any stimulation, there is the generation of substantially suppression comedo, control skin oil and fat content and have moistening effect, be particularly suitable for using in summer. Meet the multiple needs of oily skin crowd's skin protection, make oiliness skin crowd revert to healthy skin.
Chinese medicinal skin care is accepted by consumers in general and likes, and has good application prospect and market prospect price is suitable for mass consumption, be especially suitable for big production development.
Mature production technology of the present invention, steady quality.
Control oil prepared by described a kind of Chinese medicine extraction presses down pox moisture retention water, it is characterized in that the percentage by weight of Chinese prescription is: Radix Trichosanthis 10～40 parts, Flos Lonicerae 10～30 parts, Radix Puerariae 5～25 parts, Fructus Gardeniae 5～25 parts, Radix Scutellariae 5～15 parts, Cornu Bubali 1～10 part, Concha Margaritifera 1～10 part, extract wherein effective ingredient and prepare Chinese medicine control oil and press down pox moisture retention water.
Described Chinese medicine control oil presses down pox moisture retention water optimum Chinese medicinal components percentage by weight: Radix Trichosanthis 35 parts, Flos Lonicerae 20 parts, Radix Puerariae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Cornu Bubali 5 parts, Concha Margaritifera 5 parts.
The base portion weight percentages that described Chinese medicine control oil presses down pox moisture retention water is: 10～80 parts of water, glycerol 2～8 parts, butanediol 2～8 parts, propylene glycol 2～8 parts, Radix Glycyrrhizae acid amide 0.5～1.5 part, sodium alginate 0.2～1.5 part, Radix Acaciae senegalis 0.05～0.2 part, pantothenylol Methylisothiazolinone 0.2～1.5 part, methyl hydroxybenzoate 0.2～1.5 part, propyl hydroxybenzoate 0.2～1.5 part, disodiumedetate 0.2～1 part.
Described Chinese medicine control oil presses down the base portion optimum weight percentages of pox moisture retention water: glycerol 3 parts, butanediol 5 parts, propylene glycol 5 parts, Radix Glycyrrhizae acid amide 0.8 part, sodium alginate 0.5 part, Radix Acaciae senegalis 0.1 part, pantothenylol Methylisothiazolinone 0.5 part, methyl hydroxybenzoate 0.3 part, propyl hydroxybenzoate 0.4 part, disodiumedetate 0.3, water is supplemented to 100 parts.
[detailed description of the invention]
Chinese medicine optimal component in the present invention is formed into finished product citing: Radix Trichosanthis 35 parts, Flos Lonicerae 20 parts, Radix Puerariae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Cornu Bubali 5 parts, Concha Margaritifera 5 parts.
Mask matrix optimal component: glycerol 3 parts, butanediol 5 parts, propylene glycol 5 parts, Radix Glycyrrhizae acid amide 0.8 part, sodium alginate 0.5 part, Radix Acaciae senegalis 0.1 part, pantothenylol Methylisothiazolinone 0.5 part, methyl hydroxybenzoate 0.3 part, propyl hydroxybenzoate 0.4 part, disodiumedetate 0.3, water is supplemented to 100 parts.
The preparation method is that: Chinese prescription extraction purification part.
The preparation 1 of Chinese medicine extraction liquid: Radix Trichosanthis, Radix Puerariae pulverized No. 2 sieves, extracts with 40% ethanol water, filters standby.
The preparation 2 of Chinese medicine extraction liquid: water intaking Cornu Bovis seu Bubali, Margarita. Pulverizing No. 5 sieves, it is standby that the ethanol water with 10% extracts filtration.
The preparation 3 of medicament extracting solution: Flos Lonicerae pulverized No. 5 sieves, it is standby that the ethanol water with 20% extracts filtration decolouring.
The preparation 4 of medicament extracting solution: take Fructus Gardeniae, No. 5 sieves pulverized by Radix Scutellariae, it is standby that the ethanol water with 50% extracts filtration decolouring.
Merge above-mentioned 4 kinds of Chinese medicines and take liquid, for the active liquid of preserving moisture and protecting skin, standby.
Base portion: take glycerol, butanediol, propylene glycol, Radix Glycyrrhizae acid amide, sodium alginate, Radix Acaciae senegalis, pantothenylol Methylisothiazolinone, methyl hydroxybenzoate, propyl hydroxybenzoate, disodiumedetate, mixes above-mentioned several material to 50 DEG C, standby
Chinese medicine extraction liquid and substrate are blended in 50 DEG C of upper stirrings 30 minutes, filter if desired, aseptic subpackaged after cooling, as product.
Using method is the same with common moisture retention water, it is necessary to time claps, and within every 6 hours, uses once.
Pharmacological evaluation
Antiinflammatory action:
The yeast foot swelling of rat is had significantly by the mixed extract after above-mentioned merging. inhibitory action; Radix Scutellariae methanol carries
Additionally take thing and mice vascular permeability that baicalin, baicalin, wogonin all can suppress acetic acid to cause increases; Suppress the secondary lesion that the complementary arthritis degenerative bone of rat becomes, it was shown that flavones ingredient is effective to Acute and chronic inflammation. It was initially believed that the mechanisms of anti-inflammatory of Radix Scutellariae is relevant with anti-arachidonic acid (AA) metabolism.Separately have it is demonstrated experimentally that Radix Scutellariae extract can make intracellular loops adenosine phosphate (cAMP) level raise, thus suppressing mastocyte release inflammatory mediator. also play important antiinflammatory action.
Effect to microorganism
Escherichia coli, diphtheria corynebacterium, tubercule bacillus, vibrio cholera, Bacillus proteus etc. there is very strong inhibitory action.
The cells in vitro mobility that Chinese prescription extracting solution merges substantially is strengthened being can as the important mechanism of moisturizing than the cell mobilization ability not having the matched group adding extract.
The detection that staphylococcus aureus suppresses
Detection method
Prepared by test sample
Take this product extracting solution 1ml, be settled to 100ml with phosphate buffer (pH7.8 ± 0.05), as need testing solution
Staphylococcus aureus collecting cells
The nutrient agar slopes culture of depletion Staphylococcus aureus, is inoculated on nutrient agar slopes, cultivates 20～24 hours at 35～37 DEG C, is washed down by lawn with the sterilizing sodium chloride solution of 0.9%, standby.
The preparation of the flat pair of dish containing bacterium layer
A takes culture dish, is injected separately into the bactericidal nurishing agar of heat thawing, is placed on horizontal stand so that it is uniformly spread out cloth in dish, and solidification, as bottom.
B separately takes the sterilising medium Nutrient agar that above-mentioned heat is melted, and lets cool to about 50 DEG C, adds staphylococcus aureus bacteria suspension in right amount, shakes up, every a culture dish adds 5ml, makes bottom uniformly spread out cloth, as bacterium layer, be placed on horizontal stand, after solidification, put rustless steel tubule, standby.
Assay method
Take test sample and be added dropwise in rustless steel tubule in right amount, cover lid, cultivate 20～24 hours at 35～37 DEG C.
Result can obtain inhibition zone clearly.
The detection that escherichia coli suppress, with reference to above-mentioned experiment, escherichia coli minimal inhibitory concentration is 3mg/ml.
Safety examination:
Touchstone: " cosmetics health specification " (version in 2007)
The present invention is through acute oral toxicity test, and result shows that the present invention is nontoxic.
The present invention is through the many skins irritant test to skin irritation/corrosion test, and result shows that skin is almost 0 stimulation by the present invention.
The present invention is through skin Phototoxicity experiment, without photosensitivity reaction.
Claims (4)
1. the control oil that prepared by a Chinese medicine extraction presses down pox moisture retention water, it is characterized in that the percentage by weight of Chinese prescription is: Radix Trichosanthis 10～40 parts, Flos Lonicerae 10～30 parts, Radix Puerariae 5～25 parts, Fructus Gardeniae 5～25 parts, Radix Scutellariae 5～15 parts, Cornu Bubali 1～10 part, Concha Margaritifera 1～10 part, extract wherein effective ingredient and prepare Chinese medicine control oil and press down pox moisture retention water.
2. the control oil that prepared by a kind of Chinese medicine extraction as claimed in claim 1 presses down pox moisture retention water, it is characterized in that: optimum Chinese medicinal components percentage by weight is: Radix Trichosanthis 35 parts, Flos Lonicerae 20 parts, Radix Puerariae 15 parts, Fructus Gardeniae 10 parts, Radix Scutellariae 10 parts, Cornu Bubali 5 parts, Concha Margaritifera 5 parts.
3. the control oil that prepared by Chinese medicine extraction presses down a pox moisture retention water, and its spy is in that base portion weight percentages is: 10～80 parts of water, glycerol 2～8 parts, butanediol 2～8 parts, propylene glycol 2～8 parts, Radix Glycyrrhizae acid amide 0.5～1.5 part, sodium alginate 0.2～1.5 part, Radix Acaciae senegalis 0.05～0.2 part, pantothenylol Methylisothiazolinone 0.2～1.5 part, methyl hydroxybenzoate 0.2～1.5 part, propyl hydroxybenzoate 0.2～1.5 part, disodiumedetate 0.2～1 part.
4. the control oil that prepared by a kind of Chinese medicine extraction as claimed in claim 3 presses down pox moisture retention water, it is characterized in that base portion optimum weight percentages is: glycerol 3 parts, butanediol 5 parts, propylene glycol 5 parts, Radix Glycyrrhizae acid amide 0.8 part, sodium alginate 0.5 part, Radix Acaciae senegalis 0.1 part, pantothenylol Methylisothiazolinone 0.5 part, methyl hydroxybenzoate 0.3 part, propyl hydroxybenzoate 0.4 part, disodiumedetate 0.3, water is supplemented to 100 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610040007.5A CN105662994A (en) | 2016-01-18 | 2016-01-18 | Traditional Chinese medicine based oil-control anti-acne moisturizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610040007.5A CN105662994A (en) | 2016-01-18 | 2016-01-18 | Traditional Chinese medicine based oil-control anti-acne moisturizer |
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| Publication Number | Publication Date |
|---|---|
| CN105662994A true CN105662994A (en) | 2016-06-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610040007.5A Pending CN105662994A (en) | 2016-01-18 | 2016-01-18 | Traditional Chinese medicine based oil-control anti-acne moisturizer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108078866A (en) * | 2018-01-31 | 2018-05-29 | 南京海昌中药集团有限公司 | A kind of anti-inflammatory acne-removing beauty frost and preparation method and application |
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|---|---|---|---|---|
| CN1559450A (en) * | 2004-03-05 | 2005-01-05 | 北京建昊嘉信科技有限公司 | Licorice root compound for treating acne |
| CN101073545A (en) * | 2006-05-16 | 2007-11-21 | 窦玉杰 | Pox-removing face mask |
| CN101112418A (en) * | 2007-08-15 | 2008-01-30 | 济南康众医药科技开发有限公司 | Medicinal composition for part use for treating acne and method for preparing the same |
| CN103432024A (en) * | 2013-07-23 | 2013-12-11 | 无限极（中国）有限公司 | Cosmetic composition with function of removing acne |
| CN103494926A (en) * | 2013-10-12 | 2014-01-08 | 肖晓芬 | External medicine for treating rosacea and acne |
| CN104257587A (en) * | 2014-10-08 | 2015-01-07 | 杜翔宇 | Salvia miltiorrhiza and gardenia mask |
-
2016
- 2016-01-18 CN CN201610040007.5A patent/CN105662994A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1559450A (en) * | 2004-03-05 | 2005-01-05 | 北京建昊嘉信科技有限公司 | Licorice root compound for treating acne |
| CN101073545A (en) * | 2006-05-16 | 2007-11-21 | 窦玉杰 | Pox-removing face mask |
| CN101112418A (en) * | 2007-08-15 | 2008-01-30 | 济南康众医药科技开发有限公司 | Medicinal composition for part use for treating acne and method for preparing the same |
| CN103432024A (en) * | 2013-07-23 | 2013-12-11 | 无限极（中国）有限公司 | Cosmetic composition with function of removing acne |
| CN103494926A (en) * | 2013-10-12 | 2014-01-08 | 肖晓芬 | External medicine for treating rosacea and acne |
| CN104257587A (en) * | 2014-10-08 | 2015-01-07 | 杜翔宇 | Salvia miltiorrhiza and gardenia mask |
Non-Patent Citations (4)
| Title |
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| 于晓燕: "《让你年轻十岁的美肌书》", 31 May 2014, 黑龙江科学技术出版社 * |
| 李世文等: "《一味中药祛顽疾》", 30 September 2014, 人民军医出版社 * |
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| 高学敏: "《中药学》", 28 February 2003, 中国中医药出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108078866A (en) * | 2018-01-31 | 2018-05-29 | 南京海昌中药集团有限公司 | A kind of anti-inflammatory acne-removing beauty frost and preparation method and application |
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| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160615 |
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| RJ01 | Rejection of invention patent application after publication |