CN108635315A - A kind of anti-acne antiseptic - Google Patents
A kind of anti-acne antiseptic Download PDFInfo
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- CN108635315A CN108635315A CN201810474107.8A CN201810474107A CN108635315A CN 108635315 A CN108635315 A CN 108635315A CN 201810474107 A CN201810474107 A CN 201810474107A CN 108635315 A CN108635315 A CN 108635315A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses technique in skin care field, specific field is a kind of anti-acne antiseptic, and raw material group becomes:Folium sennae,Cassia angustifolia is spent,Plumage awns chrysanthemum leaf,Honeysuckle,Chinese gall,Cordate houttuynia,Radix scutellariae,Dodecyl benzyl dimethyl ammonium chloride aqueous solution and dilution tea oil,Cassia angustifolia is spent and plumage awns chrysanthemum all has stronger antibacterial action,Three is inhibited to various bacteria,After ground and alcohol extracting,Obtained concentrate,Its fungistatic effect can be further increased,Honeysuckle,Chinese gall,Cordate houttuynia etc. all has preferable fungistatic effect,It simultaneously can be clearing heat and detoxicating,Eliminate scytitis,The long acne caused by inflammation can effectively be removed,The malaise symptoms such as itch,Tea oil is the natural antibacterial agent for having greater activity,The higher tea oil of purity can cause skin to be stimulated and generate allergic reaction,Tea oil after dilution is nonirritant to human skin,A kind of anti-acne antibacterial of the present invention,Simultaneously with preferable antibacterial effect,It is nonirritant to human skin.
Description
Technical field
The present invention relates to technique in skin care field, specific field is a kind of anti-acne antiseptic.
Background technology
With people's living standards continue to improve, the nursing consciousness of skin is just gradually being enhanced, skin refers to body surface packet
Tissue outside muscle is the maximum organ of human body, mainly carries protection body, perspires, feels the work(such as cold and hot and pressure
Can, skin cover whole body, it make in vivo it is various tissue and organ from physical, mechanicalness, chemically with pathogenic microorganism
Invasion, in daily life, human skin is directly contacted with the external world, is encroached on unavoidably by various bacteriums and microorganism, such as
Timely and effective cleaning cannot be obtained, skin follicle can be made to be blocked, skin is caused the uncomfortable diseases such as long acne, itch, inflammation occur
Shape not only influences people's normal life and working condition, while can also generate and seriously affect to appearance, and it is low to make one mood, existing
Have and contain a large amount of antibiotic in in-vitro antibacterial preparation, larger to the irritation of skin, long-time service can generate skin secondary make
With so that skin is become, sensitivity is fragile, and research in recent years is found, China's Chinese traditional herbs have preferable imitate in terms of antibacterial bacteriostatic
Fruit, and there is no the irritations to skin, therefore propose a kind of anti-acne antiseptic.
Invention content
The purpose of the present invention is to provide a kind of anti-acne antiseptics, to solve the problems mentioned in the above background technology.
To achieve the above object, the present invention provides the following technical solutions：A kind of anti-acne antiseptic, raw material composition and phase
The parts by weight answered are:26~33 parts of folium sennae, cassia angustifolia spend 22~30 parts, 22~28 parts of plumage awns chrysanthemum leaf, honeysuckle 20~25, five
17~22 parts of gall nut, 16~25 parts of cordate houttuynia, 13~20 parts of radix scutellariae, dodecyl benzyl dimethyl ammonium chloride aqueous solution 10~16
Part and 6~12 parts of tea oil of dilution.
Preferably, the mass fraction of the dodecyl benzyl dimethyl ammonium chloride aqueous solution is 2%~4%.
Preferably, oil based on the diluent of the dilution tea oil, the dilution tea oil mass fraction for 10%~
20%.
Preferably, the base oil is one kind in grape seed oil, olive oil or cocounut oil.
Preferably, a kind of anti-acne antiseptic, preparation method includes the following steps：
1) it is dried after cleaning folium sennae, cassia angustifolia flower and plumage awns chrysanthemum leaf, is added in grinder and is ground into fine powder, fine silt
Diameter is 20~30 mesh, and mixing fine powders are added in extractor, is added ethanol extract into extractor, Extracting temperature is 40~
50 DEG C, after extraction, extracting solution is concentrated under vacuum, thickening temperature is 40~50 DEG C, concentrates front and back quality
Than being 1:0.75~0.85, concentrate is obtained, it is spare；
2) by honeysuckle, Chinese gall, cordate houttuynia, radix scutellariae clean after dry, then crush, powder particle diameter be 3~
Mixture after crushing is added in saucepan and cooks by 5mm, and water addition is the 4~5 of mixture gross mass in saucepan
Times, in saucepan after 25~40min of boiling water, stop cooking, filter out mixture, liquid is spare, and repetition carries out cooking 2 to mixture
It is secondary, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product in prepared product, step 2) in step 1), dodecyl benzyl dimethyl ammonium chloride aqueous solution and dilute
It releases tea oil to be uniformly mixed, through high-temperature sterilization, be cooled to room temperature.
Compared with prior art, the beneficial effects of the invention are as follows：A kind of anti-acne antiseptic, folium sennae and cassia angustifolia flower are all from
In legume cassia angustifolia, plumage awns chrysanthemum leaf comes from plumage awns chrysanthemum, and plumage awns chrysanthemum is sun plant, and folium sennae, cassia angustifolia flower and plumage awns chrysanthemum are equal
With stronger antibacterial action, three is inhibited to various bacteria, as Escherichia coli, proteus, alpha streptococcus,
Candida albicans and certain therapeutic dermatophytes etc., folium sennae, cassia angustifolia flower and after plumage awns chrysanthemum is ground and alcohol extracting, obtained concentration
Liquid can further increase its fungistatic effect, honeysuckle, Chinese gall, cordate houttuynia, radix scutellariae and dodecyl benzyl dimethyl ammonium chloride
Aqueous solution all has preferable fungistatic effect, while can be clearing heat and detoxicating, eliminates scytitis, can effectively remove caused by inflammation
The malaise symptoms such as long acne, itch, tea oil are the volatile essential oil extracted from Myrtaceae paperbark branches and leaves, tea
No matter in vivo and in vitro it is the natural antibacterial agent with greater activity to set oil, stronger suppression is all had to bacterium and fungi
System and killing effect, the higher tea oil of purity can cause skin to be stimulated and generate allergic reaction, the tea oil after dilution
Nonirritant to human skin, a kind of anti-acne antibacterial of the present invention has preferable antibacterial effect simultaneously, non-stimulated to human skin
Property.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical scheme of the present invention is clearly and completely described, it is clear that institute
The embodiment of description is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention,
Every other embodiment obtained by those of ordinary skill in the art without making creative efforts, belongs to this hair
The range of bright protection.
Embodiment 1：
1) it is dried after cleaning 260g folium sennaes, 220g cassia angustifolia flower and 220g plumage awns chrysanthemum leaves, is added in grinder and grinds
At fine powder, fine powder grain size is 20 mesh, and mixing fine powders are added in extractor, ethanol extract is added into extractor, is extracted
Temperature is 40 DEG C, and after extraction, extracting solution is concentrated under vacuum, and thickening temperature is 40 DEG C, concentrates front and back matter
Amount is than being 1:0.75, concentrate is obtained, it is spare；
2) it dries after cleaning 200g honeysuckles, 170g Chinese galls, 160g cordate houttuynias, 130g radix scutellariaes, then crushes,
Powder particle diameter is 3mm, and the mixture after crushing is added in saucepan and is cooked, and water addition is the total matter of mixture in saucepan
4 times of amount in saucepan after boiling water 25min, stop cooking, filter out mixture, and liquid is spare, and repetition cooks mixture
2 times, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, 100g dodecyl benzyl dimethyl ammonium chloride aqueous solutions in prepared product, step 2) in step 1)
It is uniformly mixed with 60g dilution tea oils, through high-temperature sterilization, is cooled to room temperature.
Embodiment 2：
1) it is dried after cleaning 280g folium sennaes, 240g cassia angustifolia flower and 240g plumage awns chrysanthemum leaves, is added in grinder and grinds
At fine powder, fine powder grain size is 25 mesh, and mixing fine powders are added in extractor, ethanol extract is added into extractor, is extracted
Temperature is 42 DEG C, and after extraction, extracting solution is concentrated under vacuum, and thickening temperature is 42 DEG C, concentrates front and back matter
Amount is than being 1:0.77, concentrate is obtained, it is spare；
2) it dries after cleaning 210g honeysuckles, 190g Chinese galls, 180g cordate houttuynias, 150g radix scutellariaes, then crushes,
Powder particle diameter is 3mm, and the mixture after crushing is added in saucepan and is cooked, and water addition is the total matter of mixture in saucepan
4 times of amount in saucepan after boiling water 29min, stop cooking, filter out mixture, and liquid is spare, and repetition cooks mixture
2 times, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, 120g dodecyl benzyl dimethyl ammonium chloride aqueous solutions in prepared product, step 2) in step 1)
It is uniformly mixed with 70g dilution tea oils, through high-temperature sterilization, is cooled to room temperature.
Embodiment 3：
1) it is dried after cleaning 300g folium sennaes, 260g cassia angustifolia flower and 260g plumage awns chrysanthemum leaves, is added in grinder and grinds
At fine powder, fine powder grain size is 25 mesh, and mixing fine powders are added in extractor, ethanol extract is added into extractor, is extracted
Temperature is 45 DEG C, and after extraction, extracting solution is concentrated under vacuum, and thickening temperature is 45 DEG C, concentrates front and back matter
Amount is than being 1:0.80, concentrate is obtained, it is spare；
2) it dries after cleaning 220g honeysuckles, 200g Chinese galls, 200g cordate houttuynias, 170g radix scutellariaes, then crushes,
Powder particle diameter is 4mm, and the mixture after crushing is added in saucepan and is cooked, and water addition is the total matter of mixture in saucepan
5 times of amount in saucepan after boiling water 32min, stop cooking, filter out mixture, and liquid is spare, and repetition cooks mixture
2 times, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, 140g dodecyl benzyl dimethyl ammonium chloride aqueous solutions in prepared product, step 2) in step 1)
It is uniformly mixed with 80g dilution tea oils, through high-temperature sterilization, is cooled to room temperature.
Embodiment 4：
1) it is dried after cleaning 320g folium sennaes, 280g cassia angustifolia flower and 270g plumage awns chrysanthemum leaves, is added in grinder and grinds
At fine powder, fine powder grain size is 28 mesh, and mixing fine powders are added in extractor, ethanol extract is added into extractor, is extracted
Temperature is 48 DEG C, and after extraction, extracting solution is concentrated under vacuum, and thickening temperature is 48 DEG C, concentrates front and back matter
Amount is than being 1:0.82, concentrate is obtained, it is spare；
2) it dries after cleaning 240g honeysuckles, 210g Chinese galls, 230g cordate houttuynias, 180g radix scutellariaes, then crushes,
Powder particle diameter is 4mm, and the mixture after crushing is added in saucepan and is cooked, and water addition is the total matter of mixture in saucepan
5 times of amount in saucepan after boiling water 36min, stop cooking, filter out mixture, and liquid is spare, and repetition cooks mixture
2 times, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, 150g dodecyl benzyl dimethyl ammonium chloride aqueous solutions in prepared product, step 2) in step 1)
It is uniformly mixed with 100g dilution tea oils, through high-temperature sterilization, is cooled to room temperature.
Embodiment 5：
1) it is dried after cleaning 330g folium sennaes, 300g cassia angustifolia flower and 280g plumage awns chrysanthemum leaves, is added in grinder and grinds
At fine powder, fine powder grain size is 30 mesh, and mixing fine powders are added in extractor, ethanol extract is added into extractor, is extracted
Temperature is 50 DEG C, and after extraction, extracting solution is concentrated under vacuum, and thickening temperature is 50 DEG C, concentrates front and back matter
Amount is than being 1:0.85, concentrate is obtained, it is spare；
2) it dries after cleaning 250g honeysuckles, 220g Chinese galls, 250g cordate houttuynias, 200g radix scutellariaes, then crushes,
Powder particle diameter is 5mm, and the mixture after crushing is added in saucepan and is cooked, and water addition is the total matter of mixture in saucepan
5 times of amount in saucepan after boiling water 40min, stop cooking, filter out mixture, and liquid is spare, and repetition cooks mixture
2 times, 3 times are cooked after liquid mixes and heats concentration, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, 160g dodecyl benzyl dimethyl ammonium chloride aqueous solutions in prepared product, step 2) in step 1)
It is uniformly mixed with 120g dilution tea oils, through high-temperature sterilization, is cooled to room temperature.
Using disk diffusion method, a kind of anti-acne antiseptic 20 of Examples 1 to 5 preparation is added dropwise respectively on every filter paper
μ L and existing In Vitro Bacteriostasis agent, criterion is that antibacterial ring size average diameter φ≤5mm is less sensitive, during 5mm ＜ φ ＜ 7mm are
Degree is sensitive, and φ >=7mm is highly sensitive, and test result is as follows under same experimental conditions：
It selects cavy to do skin irritation test, chooses 3 female cavys and 3 male cavys, 6 cavy mucous membrane of mouth are used
Sterile surgical needle scratches, and wound length is 1cm, this is an experimental group, and Examples 1 to 5 is applied to 5 experiments respectively
Existing In Vitro Bacteriostasis agent is applied in other 1 experimental group by group, respectively in 1h, for 24 hours, 48h and 72h observation wound whether there is or not
Erythema and oedema degree are set to 0~4 grade by erythema and oedema phenomenon by standard regulation, and corresponding standards of grading are as follows：
| Stimulate the reaction situation | Score value | Stimulate the reaction situation | Score value |
| Without oedema | 0 | Without erythema | 0 |
| It is visible reluctantly | 1 | Inadequate visible erythema | 1 |
| It can be seen that (edge is higher by surrounding skin) | 2 | Clearly visible erythema | 2 |
| Cutaneous protuberance 1mm, is clearly outlined | 3 | Moderate is to severe erythema | 3 |
| Oedema swells 1mm or more, and range expands | 4 | Aubergine erythema simultaneously has eschar | 4 |
It is to react average value that cavy erythema, which forms gross score and forms the sum of gross score divided by cavy sum with oedema, and reaction is flat
For mean value 0~0.49 to be nonirritant, 0.5~2.99 is slight stimulation, and 3.0~5.99 be moderate irritation, 6.0~8.0
For strong and stimulating.Experimental result is as follows：
As seen from the experiment, anti-acne antiseptic fungistatic effect of the present invention be better than existing In Vitro Bacteriostasis agent, and to skin without
Irritation.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (5)
1. a kind of anti-acne antiseptic, it is characterised in that：Its raw material forms and corresponding parts by weight are:Folium sennae 26~33
Part, cassia angustifolia spend 22~30 parts, 22~28 parts of plumage awns chrysanthemum leaf, honeysuckle 20~25,17~22 parts of Chinese gall, cordate houttuynia 16~25
Part, 13~20 parts of radix scutellariae, 10~16 parts of dodecyl benzyl dimethyl ammonium chloride aqueous solution and 6~12 parts of tea oil of dilution.
2. a kind of anti-acne antiseptic according to claim 1, it is characterised in that：The dodecyl dimethyl Benzylmagnesium chloride
The mass fraction of aqueous ammonium is 2%~4%.
3. a kind of anti-acne antiseptic according to claim 1, it is characterised in that：The diluent of the dilution tea oil is base
Plinth oil, the dilution tea oil mass fraction are 10%~20%.
4. a kind of anti-acne antiseptic according to claim 2, it is characterised in that：The base oil is grape seed oil, olive
One kind in oil or cocounut oil.
5. a kind of anti-acne antiseptic according to claim 1, it is characterised in that：Preparation method includes the following steps：
1) it is dried after cleaning folium sennae, cassia angustifolia flower and plumage awns chrysanthemum leaf, is added in grinder and is ground into fine powder, fine powder grain size is
20~30 mesh, mixing fine powders are added in extractor, and ethanol extract is added into extractor, and Extracting temperature is 40~50
DEG C, after extraction, extracting solution is concentrated under vacuum, thickening temperature is 40~50 DEG C, concentrates front and back mass ratio
It is 1:0.75~0.85, concentrate is obtained, it is spare；
2) it dries after cleaning honeysuckle, Chinese gall, cordate houttuynia, radix scutellariae, then crushes, powder particle diameter is 3~5mm, will
Mixture after crushing, which is added in saucepan, to be cooked, and water addition is 4~5 times of mixture gross mass in saucepan, saucepan
After middle 25~40min of boiling water, stop cooking, filter out mixture, liquid is spare, repeats to mixture cook 2 times, by 3
Concentration is heated after secondary cooking liquid mixing, is concentrated into the 1/3 of original volume, it is spare；
3) by prepared product, dodecyl benzyl dimethyl ammonium chloride aqueous solution and dilution tea in prepared product, step 2) in step 1)
Tree oil is uniformly mixed, and through high-temperature sterilization, is cooled to room temperature.
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| CN201810474107.8A CN108635315A (en) | 2018-05-17 | 2018-05-17 | A kind of anti-acne antiseptic |
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| CN201810474107.8A CN108635315A (en) | 2018-05-17 | 2018-05-17 | A kind of anti-acne antiseptic |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961315A (en) * | 2012-12-10 | 2013-03-13 | 晓健科技（大连）有限公司 | Traditional Chinese medicine acne removing essence |
| CN103432024A (en) * | 2013-07-23 | 2013-12-11 | 无限极（中国）有限公司 | Cosmetic composition with function of removing acne |
| CN104434609A (en) * | 2013-09-13 | 2015-03-25 | 广东轻工职业技术学院 | Compound traditional Chinese medicine extract with acne removing function and application thereof in cosmetics |
-
2018
- 2018-05-17 CN CN201810474107.8A patent/CN108635315A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102961315A (en) * | 2012-12-10 | 2013-03-13 | 晓健科技（大连）有限公司 | Traditional Chinese medicine acne removing essence |
| CN103432024A (en) * | 2013-07-23 | 2013-12-11 | 无限极（中国）有限公司 | Cosmetic composition with function of removing acne |
| CN104434609A (en) * | 2013-09-13 | 2015-03-25 | 广东轻工职业技术学院 | Compound traditional Chinese medicine extract with acne removing function and application thereof in cosmetics |
Non-Patent Citations (2)
| Title |
|---|
| V． KRISHNAVENI KUMARAGURU 技术学院: "《用于皮肤病的草本抗菌剂产品的开发》", 《国际纺织导报》 * |
| 郑兰娟: "《五倍子抗菌抗炎作用研究进展》", 《中国病原生物学杂质》 * |
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