CN106511570A - Herbal powder used for porcine circovirus and/or porcine reproductive and respiratory syndrome, and preparation method and application thereof - Google Patents
Herbal powder used for porcine circovirus and/or porcine reproductive and respiratory syndrome, and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses herbal powder used for porcine circovirus and/or porcine reproductive and respiratory syndrome. The herbal powder is prepared from the following raw materials in parts by weight: 25-35 parts of rhizoma coptidis, 55-65 parts of radix scutellariae, 55-65 parts of cortex phellodendri, 40-50 parts of fructus gardeniae, 55-65 parts of radix isatidis, 55-65 parts of folium isatidis, 25-35 parts of rheum officinale, 55-65 parts of gypsum, 55-65 parts of sodium sulfate powder, 35-45 parts of flos lonicerae, 25-35 parts of fructus forsythiae, 25-40 parts of radix astragali, 25-40 parts of radix codcnopsitis pilosulas, 35-45 parts of poria cocos, 2-4 parts of fructus anisi stellati and 2-4 parts of fructus foeniculi. According to the herbal powder provided by the invention, the clearance rate of the porcine circovirus and/or the porcine reproductive and respiratory syndrome reaches more than 90%, so that the clearance efficiency is high; the immune function can be quickly activated, the anti-infection ability is enhanced, the disease incidence rate is reduced, virus replication is prevented, virus spread is controlled, the morbidity of the porcine circovirus and/or the porcine reproductive and respiratory syndrome is reduced, macrophage functions are regulated, and the occurrence and development of recessive porcine reproductive and respiratory syndromes are controlled; and easily volatile components are added under a low-temperature condition in a preparation process, so that the volatility of the components is reduced and the drug effect of the herbal powder is improved.
Description
Technical field
The invention belongs to Chinese herbal medicine preparation technology field, and in particular to a kind of in pig circular ring virus 2 and/or reproductive and respiratory syndrome
Powdered medicine and its preparation method and application.
Background technology
Pig circular ring virus (Porcine circovirus, abbreviation：PCV) it is a kind of minimum zoosis that find so far
Poison.Know that PCV has two serotypes, i.e. PCV1 and PCV2.Viruses of the PCV1 for non-pathogenic.PCV2 is pathogenic disease
Poison, it be pmws (Postweaning Multisystemic Wasting Syndrome,
PMWS main pathogen).Primary disease is found in Canadian (1991) earliest, and in American-European and Asia, some countries are sent out including China quickly
It is raw and popular, in addition to PMWS, PDNS (Corii Sus domestica inflammation and nephrotic syndrome), PNP (Hypertrophic necrotizing pneumonia), PRDC (pig breathings
Tract disease syndrome), breeding difficulty, it is congenital tremble, the disease such as enteritis is also with PCV2 infected with important association.PCV2 and its phase
The swine diseasess of pass, mortality rate 10%～30%, the more serious pig farm mortality rate when primary disease is broken out are up to 40%, to pig industry
Cause serious economic loss.It is known as being after Porcine reproductive and respiratory syndrome with pig dealer by the veterinary of countries in the world
(PRRS) the newfound Important Infectious Diseases for causing pig dysimmunity after.
Reproductive and respiratory syndrome is a kind of highly contagious disease, in endemicity.This tower of the cause of disease also known as FilippoGammarelli of primary disease is viral
(Lelysted virus) is shell type viraleses (Nidovirales), Arteriviridae (Arteriviridac), arteritis
The Reproductive and respiratory syndrome virus (PRRSV) of Tobamovirus (Arterivirirus).PRRSV infected pigs, various kinds, no
Can infect with the pig of age and purposes, but it is most susceptible with in-pig and the piglet within 1 monthly age.Ill pig and the malicious pig of band are
The important source of infection of primary disease.Major transmission path is that contact infection, air borne and seminal fluid are propagated, and also can vertically be passed by Placenta Hominiss
Broadcast.Susceptible pig can orally, nasal cavity, muscle, abdominal cavity, vein and intrauterine inoculation etc. number of ways and infect virus, pig infection disease
Other susceptible pigs can be given by virus disseminating by contact within 2～14 weeks after poison.Can detect in nasal cavity, feces and urine from sick pig
To virus.Susceptible pig with have the means of transport of PRRSV, device contacts be infected with malicious pig directly contact or with pollution.
The flowing of infected pigs is also the important circulation way of primary disease.
Persistent infection is the EPDML key characters of PRRS, and PRRSV can be in presence in infected pigs' body for a long time.
Herbal medicine is long in China's developing history, content, rich connotation, and the development for China's animal husbandry for thousands of years is made
Huge contribution.Herbal medicine treatment in accordance with local conditions, gathers materials on the spot, and curative effect persistently, does not have or very
Rare side effect.With the enhancing of people's health consciousness, people improve to the attention rate of the problem of the safety of stockbreeding production, shake
The emerging herbal medicine traditional with development China becomes a urgent realistic problem.
In order to fully excavate pools of traditional Chinese medicine, green cultivation platform is built, explore the road of Chinese medicine healthy aquaculture, explore compound recipe
Impact of the Chinese medicine product to reproductive and respiratory syndrome poison and porcine circovirus, to reduce, control even abandon producer to antibiotic and disease-resistant
The dependency of cytotoxic drug is using becoming inexorable trend.But a few taste medicines are simply carried out simple powder by traditional handicraft in preparation method
It is broken, sieve, mix, obtain final product.Its grinding particle size is very thick, take orally absorb it is bad, the high temperature in crushing process also make part effectively into
Divide loss, reduce further product drug effect.
The content of the invention
Present invention defect of the prior art for more than provides a kind of Chinese powder medicine, and the Chinese powder medicine can be to annulus
Disease and reproductive and respiratory syndrome effectively, have reached more than 90% to the clearance rate of virus simultaneously.
The purpose of the present invention is achieved through the following technical solutions：
It is a kind of to be counted for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome by weight, including：25～35 parts of Rhizoma Coptidis,
55～65 parts of Radix Scutellariae, 55～65 parts of Cortex Phellodendri, 40～50 parts of Fructus Gardeniae, 55～65 parts of Radix Isatidis, 55～65 parts of Folium Isatidiss, Radix Et Rhizoma Rhei 25～
35 parts, 55～65 parts of Gypsum Fibrosum, 55～65 parts of Matrii Sulfas Exsiccatus, 35～45 parts of Flos Lonicerae, 25～35 parts of Fructus Forsythiae, 25～40 parts of the Radix Astragali, party
25～40 parts of ginseng, 35～45 parts of Poria, 2～4 parts of Fructus Anisi Stellati, 2～4 parts of Fructus Foeniculi.
Further, count by weight, including：30 parts of Rhizoma Coptidis, 60 parts of Radix Scutellariae, 60 parts of Cortex Phellodendri, 45 parts of Fructus Gardeniae, Radix Isatidis
60 parts, 60 parts of Folium Isatidiss, 30 parts of Radix Et Rhizoma Rhei, 60 parts of Gypsum Fibrosum, 60 parts of Matrii Sulfas Exsiccatus, 40 parts of Flos Lonicerae, 30 parts of Fructus Forsythiae, 30 parts of the Radix Astragali, party
30 parts of ginseng, 40 parts of Poria, 2 parts of Fructus Anisi Stellati, 3 parts of Fructus Foeniculi.
It is a kind of for pig circular ring virus 2 and/or the preparation method of the Chinese powder medicine of reproductive and respiratory syndrome, comprise the steps：
S1：Weigh respectively by weight raw material Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum,
Matrii Sulfas Exsiccatus, Flos Lonicerae, Fructus Forsythiae, the Radix Astragali, Radix Codonopsis, Poria, Fructus Anisi Stellati, Fructus Foeniculi, it is standby；
S2：By Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum, Matrii Sulfas Exsiccatus, the Radix Astragali, Radix Codonopsis, Fu
Crush after Siberian cocklebur mixing, cross 24～80 mesh sieves, obtain coarse powder；
S3：By coarse powder under cryogenic continue crush, in the crushing process of coarse powder, successively mix Flos Lonicerae, Fructus Forsythiae,
Fructus Anisi Stellati and Fructus Foeniculi are crushed together with the coarse powder obtained by step S2, cross 200～400 mesh sieves, obtain fine powder after crushing；
S4：The fine powder of gained in step S3 is loaded into mix homogeneously in mixer, subpackage is carried out, is packed, is obtained final product powder of Chinese traditional medicine
Agent.
Further, cryogenic conditions described in step S3 are 0～4 DEG C.
Further, cryogenic conditions described in step S3 are realized by being passed through low-temperature cooling water in casing is crushed.
Further, in step S3, in the crushing process of coarse powder, Flos Lonicerae, Fructus Forsythiae, Fructus Anisi Stellati and little are entered disastrously successively
Fructus Foeniculi is crushed together with the coarse powder obtained by step S2, and 300 mesh sieves are crossed after crushing.
Further, Chinese powder medicine is yellow to filemot powder；Gas perfume, bitter in the mouth, micro-puckery；Thin layer differentiates to detect Huang
Company, Fructus Gardeniae, Radix Scutellariae, Radix Et Rhizoma Rhei, chlorogenic acid；Moisture≤10%；Appearance uniform degree should be presented uniform color and luster, without decorative pattern, color
Speckle.
Present invention also offers a kind of Chinese powder medicine for pig circular ring virus 2 and/or reproductive and respiratory syndrome is being prepared for preventing or controlling
Treat the application in the medicine of pig circular ring virus 2 and/or reproductive and respiratory syndrome.
When preparing for treating pig circular ring virus 2 and/or reproductive and respiratory syndrome, the using dosage of the Chinese powder medicine is：
1. the Chinese powder medicine of 3.5kg～4.5kg, free choice feeding is added to be used in conjunction 7～14 days in water per ton or feedstuff；It is excellent
Choosing, 4kg is added in water per ton or feedstuff；
Or 2. Chinese powder medicine is mixed with feedstuff according to being the ratio of 0.2g/kg～0.4g/kg with the weight ratio of pig
It is even, take orally, daily 2 times, be used in conjunction 7～14 days.
When the medicine for being used to preventing pig circular ring virus 2 and/or reproductive and respiratory syndrome is prepared, the using dosage of the Chinese powder medicine is：
1. the Chinese powder medicine of 1.5kg～2.5kg is added in water per ton or feedstuff, free choice feeding is continuous to feed 4 weeks；
Or 2. the Chinese powder medicine that whole day need to be fed is calculated according to the Chinese powder medicine that 1.5kg～2.5kg is added in feedstuff per ton
Total amount, be added into a small amount of feedstuff and disposably feed, it is continuous to feed 4 weeks.
Compared with prior art, the present invention at least has advantages below：
1st, the Chinese powder medicine that the present invention is provided has reached more than 90% to the clearance rate of porcine circovirus and reproductive and respiratory syndrome poison, removes
Efficiency high.
2nd, immune function can be quickly activated, strengthens itself anti-infection ability, reduce disease incident.
3rd, virus replication is prevented, controls virus spread, reduce annulus, blue ear sickness rate.
4th, macrophage function is adjusted, the recessive reproductive and respiratory syndrome of control occurs and development.
5th, the present invention provide Chinese powder medicine to escherichia coli, pasteurellosis bacilluss, Salmonella, streptococcus, streptococcus pneumoniae,
Substance, Actinobacillus pleuropneumoniae, haemophilus parasuises, staphylococcuses, necrobacillus, Listeria monocytogeness, Eperythrozoon etc. are
There are powerful lethality, effective control intestinal infection, urogenital infections, respiratory tract infection, septicemia, various mixed infections
And secondary infection.
6th, the present invention is employed when the Chinese powder medicine is prepared, and reducing should
The volatility of composition, improves the efficacy of Chinese powder medicine.
Description of the drawings
Fig. 1 is the technological process of the preparation method of the Chinese powder medicine provided by the present invention for pig circular ring virus 2 and/reproductive and respiratory syndrome
Figure.
Specific embodiment
To make purpose, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention
In accompanying drawing, the technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
The a part of embodiment of the present invention, rather than the embodiment of whole.Therefore, embodiments of the invention below to providing in the accompanying drawings
Detailed description be not intended to limit the scope of claimed invention, but be merely representative of the selected embodiment of the present invention.
Based on the embodiment in the present invention, it is all that those of ordinary skill in the art are obtained under the premise of creative work is not made
Other embodiment, belongs to the scope of protection of the invention.
It is exemplary below with reference to the embodiment of Description of Drawings, it is intended to for explaining the present invention, and be not understood that
For limitation of the present invention.
The present invention is further illustrated with specific embodiment below with reference to accompanying drawings.
The prepared slices of Chinese crude drugs mentioned in the present invention meet existing《Republic of China Veterinary Pharmacopoeia》The standard of two.
In the formula of the present invention：
Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication；
Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, hemostasis are antiabortive；
Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever；
Fructus Gardeniae eliminating fire and detoxication, clearing away heat and promoting diuresis, removing heat from blood；
Radix Isatidis heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving；
Folium Isatidiss heat-clearing and toxic substances removing, blood cooling and ecchymoses removing；
Radix Et Rhizoma Rhei purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, removing mass clots absorbing；
Gypsum Fibrosum clearing away heat-fire, promoting the production of body fluid to quench thirst；
Matrii Sulfas Exsiccatus purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat；
Flos Lonicerae heat-clearing and toxic substances removing, radiate dispelling wind；
Fructus Forsythiae heat-clearing and toxic substances removing, dispersing swelling and dissipating binds；
Radix Astragali tonifying Qi and lifting yang, benefit defend consolidating superficial resistance, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation；
Radix Codonopsis invigorating the spleen and replenishing QI, strengthening spleen and tonifying lung；Poria eliminating dampness and diuresises, spleen invigorating mind calming；
Fructus Anisi Stellati warming YANG to expel cold, regulating QI to relieve pain；
Fructus Foeniculi dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.
All medicines share, has eliminating fire and detoxication, heat-clearing and toxic substances removing, pathogenic fire purging relieving constipation.Cure mainly excessive heat in SAN JIAO, skin ulcer general edema with yellowish skin poison, heating, excrement
It is dry.The mixed infection and secondary infection of various bacillary, viral diseases is can be clinically used for, body's immunity can be improved, increased
Strong itself anti-infection ability, can effectively reduce the sickness rate of the viral diseases such as pig annulus, blue ear.
Provided by the present invention for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, count by weight, including：
It is 25～35 parts of Rhizoma Coptidis, 55～65 parts of Radix Scutellariae, 55～65 parts of Cortex Phellodendri, 40～50 parts of Fructus Gardeniae, 55～65 parts of Radix Isatidis, big
55～65 parts of Folium Isatidis, 25～35 parts of Radix Et Rhizoma Rhei, 55～65 parts of Gypsum Fibrosum, 55～65 parts of Matrii Sulfas Exsiccatus, 35～45 parts of Flos Lonicerae, Fructus Forsythiae 25～
35 parts, 25～40 parts of the Radix Astragali, 25～40 parts of Radix Codonopsis, 35～45 parts of Poria, 2～4 parts of Fructus Anisi Stellati, 2～4 parts of Fructus Foeniculi.
Such as Fig. 1, provided by the present invention for pig circular ring virus 2 and/or the preparation method of the Chinese powder medicine of reproductive and respiratory syndrome, including such as
Lower step：
S1：Weigh respectively by weight raw material Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum,
Matrii Sulfas Exsiccatus, Flos Lonicerae, Fructus Forsythiae, the Radix Astragali, Radix Codonopsis, Poria, Fructus Anisi Stellati, Fructus Foeniculi, it is standby；
S2：By Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum, Matrii Sulfas Exsiccatus, the Radix Astragali, Radix Codonopsis, Fu
Crush after Siberian cocklebur mixing, cross 24～80 mesh sieves, obtain coarse powder；
S3：Coarse powder is continued to crush for (0～4 DEG C) under cryogenic, in the crushing process of coarse powder, gold silver is mixed successively
Flower, Fructus Forsythiae, Fructus Anisi Stellati and Fructus Foeniculi are crushed together with the coarse powder obtained by step S2.200～400 mesh sieves are crossed after crushing, preferably
, 300 mesh sieves are crossed, fine powder is obtained；
Can keep whole crushing process using the low-temperature cooling water that circulation is passed through in casing is crushed or other modes
(0～4 DEG C) is carried out under cryogenic.Low-temperature grinding effective protection some compositions in crushing process are made because temperature is too high
Into loss, improve Chinese powder medicine drug effect.
During crushing, oil components can be absorbed by coarse powder in time that first crush so as to be no longer attached to pulverizer
Or sieve aperture.
In addition, the smashing fineness of product has reached 200～400 mesh in the present invention, traditional mode of production smashing fineness is typically 24
～100 mesh.The granularity of 200 mesh has reached 74 μm, and the granularity of 300 mesh has reached 48 μm, belongs to Chinese medicine ultra-fine powder.Chinese medicine ultra-fine powder
After broken, for general medical material, the cell-wall breaking ratio under the conditions of the fineness is up to more than 60%.Cell is intracellular Jing after breaking cellular wall
Effective ingredient fully comes out, and the rate of release and burst size of medicine can be greatly improved, can batch mixing use, also can be in aqueous solution
Middle even suspension and adopt drinking water administration, can substantially increase oral preparations solution absorption degree in vivo, and useful less dose
Amount meets or exceeds the general curative effect for crushing original side.
S4：Fine powder obtained by step S3 is loaded in mixer and is always mixed 30min, fine powder is sufficiently mixed uniformly, then
Subpackage is carried out, is packed, is obtained final product Chinese powder medicine.
Provided by the present invention for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome character be yellow to filemot powder
End；Gas perfume, bitter in the mouth, micro-puckery；Thin layer differentiates to detect Rhizoma Coptidis, Fructus Gardeniae, Radix Scutellariae, Radix Et Rhizoma Rhei, chlorogenic acid；Water is determined with reference to oven drying method
Point content should must not exceed 10%；Appearance uniform degree should be presented uniform color and luster, without decorative pattern, mottle；Granularity all should be able to pass through
300 mesh standard sieves；Loading amount should be no less than the sign loading amount of packaging.
Provided by the present invention for pig circular ring virus 2 and/or the using method of the Chinese powder medicine of reproductive and respiratory syndrome：
1st, treatment infection：Take 3.5～4.5kg of this product, preferably 4kg, batch mixing or be watered 1000kg, free choice feeding；
Or be 0.2～0.4g by the consumption of every 1kg body weight, mix appropriate feedstuff and once take orally, daily 2 times, be used in conjunction 7～14 days.
2nd, prevention and health care：Take 1.5～2.5kg of this product, preferably 2kg, batch mixing or be watered 1000kg.To mitigate batch mixing
Labor intensity, according to whole day feedstuff consumption conversion whole day Traditional Chinese Medicine dosage, mixes a small amount of feedstuff and once feeds.In order to effectively reduce swinery
Annulus and blue ear positive rate, are used in conjunction 4 weeks using this programme first.
Embodiment 1
Provided by the present invention for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, count by weight, it is specific to wrap
Include：
30 parts of Rhizoma Coptidis, 60 parts of Radix Scutellariae, 60 parts of Cortex Phellodendri, 45 parts of Fructus Gardeniae, 60 parts of Radix Isatidis, 60 parts of Folium Isatidiss, 30 parts of Radix Et Rhizoma Rhei, stone
60 parts of cream, 60 parts of Matrii Sulfas Exsiccatus, 40 parts of Flos Lonicerae, 30 parts of Fructus Forsythiae, 30 parts of the Radix Astragali, 30 parts of Radix Codonopsis, 40 parts of Poria, 2 parts of Fructus Anisi Stellati,
3 parts of Fructus Foeniculi.
Embodiment 2
Provided by the present invention for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, count by weight, it is specific to wrap
Include：
25 parts of Rhizoma Coptidis, 55 parts of Radix Scutellariae, 60 parts of Cortex Phellodendri, 40 parts of Fructus Gardeniae, 60 parts of Radix Isatidis, 65 parts of Folium Isatidiss, 30 parts of Radix Et Rhizoma Rhei, stone
60 parts of cream, 55 parts of Matrii Sulfas Exsiccatus, 45 parts of Flos Lonicerae, 35 parts of Fructus Forsythiae, 35 parts of the Radix Astragali, 30 parts of Radix Codonopsis, 40 parts of Poria, 4 parts of Fructus Anisi Stellati,
2 parts of Fructus Foeniculi.
Embodiment 3
Provided by the present invention for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, count by weight, specifically include：
35 parts of Rhizoma Coptidis, 65 parts of Radix Scutellariae, 55 parts of Cortex Phellodendri, 50 parts of Fructus Gardeniae, 65 parts of Radix Isatidis, 55 parts of Folium Isatidiss, 35 parts of Radix Et Rhizoma Rhei, stone
65 parts of cream, 65 parts of Matrii Sulfas Exsiccatus, 45 parts of Flos Lonicerae, 35 parts of Fructus Forsythiae, 25 parts of the Radix Astragali, 25 parts of Radix Codonopsis, 45 parts of Poria, 2 parts of Fructus Anisi Stellati,
4 parts of Fructus Foeniculi.
4 the present embodiment 1-3 product clinical practices of embodiment
1) experimental subject：Select with Repeat breeding, return the breeding difficulty diseases such as feelings rate height, miscarriage, stillborn fetuses, weak tire, break
Before and after milk, Piglet Development is bad, becomes thin, anemia, and diarrhoea, cough with asthma, interstitial pneumonia, cad pig are more, and death rate is higher, protects
Educate that pig sickness rate is higher, blue ear, annulus feature pig substantially etc..Experimental subject derives from three pig farms, is respectively designated as A, B, C
Pig farm.
A pig farms：Many cultivation company limited (grow up two-way cross sow) are closed in Sichuan Yibin, choose Suprapubic arch sling 67；
B pig farms：Three layers of Chongqing City rock livestock and poultry farm (DLY three way cross piglet), chooses or so 1 monthly age wean young
Pig 70；
C pig farms：Pig farm (long honor two-way cross piglet) is planted by Chongqing City, chooses 1 monthly age or so ablactational baby pig 68.
2) A, B, C pig farm is randomly divided into into two groups, one group is test group, and one group is matched group, and test group is in feedstuff
Addition the present embodiment 1 provide Chinese powder medicine 2kg/ ton feedstuffs, be used in conjunction 60 days, matched group without.
Blood serum sample is gathered：The test group and matched group on three pig farms, in 0 day, 4 weeks, vena cava anterior blood sampling in 8 weeks, separates
Serum, -20 DEG C of Refrigerator store censorships.
Rongchang County of Southwestern University school district quick diagnosis center is sent to carry out reproductive and respiratory syndrome viral disease RT-PCR, annulus respectively tested serum
Virosiss PCR are detected.
3) result of the test
A pig farms reproductive and respiratory syndrome viral disease RT-PCR, circovirus disease PCR testing results, refer to table 1.
The Chinese powder medicine that the present embodiment 1 is provided in 1 A pig farms of table is to reducing annulus indigo plant ear positive rate result of the test statistical table
Note：* represent significant difference (P<0.05), * * represent difference extremely significantly (P<0.01).
From table 1 it follows that after A pig farms are fed 4 weeks using the Chinese powder medicine that the present embodiment 1 is provided, reproductive and respiratory syndrome
(PRRS) positive rate drops to 6.06% by 36.36%, and porcine circovirus positive rate is reduced to 9.09% by 45.45%, reproductive and respiratory syndrome poison
3.03% is down to by 27.28% with the positive rate of porcine circovirus mixed infection；After using 8 weeks, blue ear, annulus and blue ear annulus are mixed
Close infection positive rate and be reduced to 3.03%, 3.03% and 3.03% respectively, decline clearly, with significantly removing virus effect
Really, clearance rate reaches more than 90%；And matched group 0 week, 4 weeks, after 8 weeks, reproductive and respiratory syndrome positive rate is respectively 41.18%,
32.25%th, 30.00%, porcine circovirus positive rate is respectively 47.06%, 41.98%, 33.33%, and blue ear and annulus mixing are felt
Dye positive rate is respectively 29.41%, 25.80%, 23.33%, and 4 weeks and 8 weeks because of mixed infection dead 4 altogether.
Conclusion：This product 2kg/ ton feedstuff is taken, sow field indigo plant ear and annulus can be effectively removed in uninterrupted feeding 4 weeks or 8 weeks
Virus, reduces positive rate, compared with matched group, with pole significant difference, can effective control sow field indigo plant ear, annulus and its mixing
The generation of infection.
Using suggestion：For sow field, the Chinese powder medicine 2kg/ ton feedstuffs provided in taking the present embodiment 1, use for the first time
This product, continuous feeding 4 weeks or 8 weeks；Whenever the discontinuous method administration of 4 week using feeding 4 weeks, can be disabled later.
B pig farms reproductive and respiratory syndrome viral disease RT-PCR, circovirus disease PCR testing results, refer to table 2.
The Chinese powder medicine that the present embodiment 1 is provided in 2 B pig farms of table is to reducing annulus indigo plant ear positive rate result of the test statistical table
Note：* represent significant difference (P<0.05), * * represent difference extremely significantly (P<0.01).
From Table 2, it can be seen that after B pig farms are fed 4 weeks using the Chinese powder medicine that the present embodiment 1 is provided, reproductive and respiratory syndrome
(PRRS) positive rate drops to 5.56% by 27.78%, and porcine circovirus positive rate is reduced to 8.33% by 36.11%, blue ear and circle
Ring mixed infection positive rate is down to 5.56% by 22.22%；After using 8 weeks, blue ear, annulus and the mixed infection of blue ear annulus are positive
Rate is reduced to 2.78%, 2.78% and 2.78% respectively, declines clearly, and with virus effectiveness is significantly removed, clearance rate reaches
To more than 90%；And matched group 0 week, 4 weeks, after 8 weeks, reproductive and respiratory syndrome positive rate is respectively 26.47%, 26.66%, 31.03%, circle
Circovirus virus positive rate is respectively 35.29%, 36.66%, 37.93%, and blue ear and annulus mixed infection positive rate are respectively
20.59%th, 23.33%, 24.14%, 4 weeks and 8 weeks because of mixed infection dead 5 altogether.
Conclusion：The Chinese powder medicine 2kg/ ton feedstuffs that the present embodiment 1 is provided, continuous feeding 4 weeks or 8 weeks, can effectively remove pig
The blue ear in field and porcine circovirus, reduce positive rate, compared with matched group, with pole significant difference, can effective control pig farm indigo plant ear, circle
Ring and its sickness rate of mixed infection.
C pig farms reproductive and respiratory syndrome viral disease RT-PCR, circovirus disease PCR testing results, refer to table 3.
The Chinese powder medicine that the present embodiment 1 is provided in 3 C pig farms of table is to reducing annulus indigo plant ear positive rate result of the test statistical table
Note：* represent significant difference (P<0.05), * * represent difference extremely significantly (P<0.01).
From table 3 it is observed that after C pig farms are fed 4 weeks using the Chinese powder medicine that the present embodiment 1 is provided, reproductive and respiratory syndrome
(PRRS) positive rate drops to 5.71% by 22.85%, and porcine circovirus positive rate is reduced to 8.57% by 31.43%, blue ear and circle
The positive rate of ring mixed infection is down to 5.71% by 17.14%；After using 8 weeks, blue ear, annulus and blue ear annulus mixed infection sun
Property rate be respectively 2.86%, 2.86% and 2.86%, decline clearly, with virus effectiveness is significantly removed, clearance rate reaches
To more than 90%；And matched group 0 week, 4 weeks, after 8 weeks, reproductive and respiratory syndrome poison positive rate is respectively 21.21%, 19.35%, 17.24%,
Porcine circovirus positive rate is respectively 30.30%, 29.03%, 27.59%, and blue ear and annulus mixed infection positive rate are respectively
18.18%th, 16.13%, 13.79%, 4 weeks and 8 weeks because of mixed infection dead 4 altogether.
Conclusion：The Chinese powder medicine 2kg/ ton feedstuffs that the present embodiment 1 is provided, continuous feeding 4 weeks or 8 weeks, can effectively remove pig
The blue ear in field and porcine circovirus, reduce positive rate, compared with matched group, with pole significant difference, can effective control pig farm indigo plant ear, circle
Ring and its sickness rate of mixed infection.
Using suggestion：For porkling, the Chinese powder medicine 2kg/ ton feedstuffs of the offer of the present embodiment 1, religion groove phase and child care phase are taken
Whole to use, nursery house transformation fertilizer house is used in conjunction 2 weeks；Next it is discontinued 2 weeks, later by with 4 weeks, stops 4 weeks, then with the interruption of 4 weeks
Formula mode is added, until delivering for sale.
The Chinese powder medicine provided using the embodiment of the present invention 2 and 3 is tested, and has also obtained same effect and conclusion.
The Chinese powder medicine that the present invention is provided has advantages below：
1. used as the topmost dosage form of herbal medicine, traditional production method is all simple from rudimentary medical material Jing to powder
Crushing, sieve, be mixed.The present invention solves raw material from source bad first from the tcm and herbal slice prescription of high-quality
The problem for causing product curative effect bad；
2. low-temperature grinding is employed in the preparation method of the present invention, effectively reduce crushing high temperature to some effective ingredient institutes
The loss for causing；
3. the grinding particle size in the present invention is very thin, the rate of release and burst size of ingredient in medical material significantly can be carried
Height, can batch mixing use, also can in aqueous even suspension and adopt drinking water administration, can substantially increase oral preparations in vivo
Solution absorption degree, so as to the general curative effect for crushing original side can be met or exceeded using smaller dose；
4. the loss of the effective ingredient that low-temperature grinding can be during effective protection pulverizing medicinal materials, but cost is crushed accordingly
It is higher, therefore, present invention employs and low-temperature grinding and routinely crush the preparation method for combining, a part with reference to actual selection
First after conventional crushing, adding the component containing volatile effective ingredient carries out superfine comminution at low temperature, so as to ensure that medicine
Effect, also reduces cost.
More than, the only present invention preferably specific embodiment, but the protection domain invented is not limited thereto, any ripe
Know those skilled in the art the invention discloses technical scope in, the change or replacement that can be readily occurred in should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be defined by the protection domain of claims.
Claims (10)
1. it is a kind of for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, it is characterised in that to count by weight, including：
25～35 parts of Rhizoma Coptidis, 55～65 parts of Radix Scutellariae, 55～65 parts of Cortex Phellodendri, 40～50 parts of Fructus Gardeniae, 55～65 parts of Radix Isatidis, Folium Isatidiss
55～65 parts, 25～35 parts of Radix Et Rhizoma Rhei, 55～65 parts of Gypsum Fibrosum, 55～65 parts of Matrii Sulfas Exsiccatus, 35～45 parts of Flos Lonicerae, Fructus Forsythiae 25～35
Part, 25～40 parts of the Radix Astragali, 25～40 parts of Radix Codonopsis, 35～45 parts of Poria, 2～4 parts of Fructus Anisi Stellati, 2～4 parts of Fructus Foeniculi.
2. it is according to claim 1 for pig circular ring virus 2 and/or the Chinese powder medicine of reproductive and respiratory syndrome, it is characterised in that by weight
Number meter, including：
30 parts of Rhizoma Coptidis, 60 parts of Radix Scutellariae, 60 parts of Cortex Phellodendri, 45 parts of Fructus Gardeniae, 60 parts of Radix Isatidis, 60 parts of Folium Isatidiss, 30 parts of Radix Et Rhizoma Rhei, Gypsum Fibrosum 60
Part, 60 parts of Matrii Sulfas Exsiccatus, 40 parts of Flos Lonicerae, 30 parts of Fructus Forsythiae, 30 parts of the Radix Astragali, 30 parts of Radix Codonopsis, 40 parts of Poria, 2 parts of Fructus Anisi Stellati, Fructus Foeniculi
It is fragrant 3 parts.
3. a kind of according to claim 1 and 2 for pig circular ring virus 2 and/or the preparation method of the Chinese powder medicine of reproductive and respiratory syndrome,
Characterized in that, comprising the steps：
S1：Weigh raw material Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum, profound bright by weight respectively
Powder, Flos Lonicerae, Fructus Forsythiae, the Radix Astragali, Radix Codonopsis, Poria, Fructus Anisi Stellati, Fructus Foeniculi, it is standby；
S2：Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, Fructus Gardeniae, Radix Isatidis, Folium Isatidiss, Radix Et Rhizoma Rhei, Gypsum Fibrosum, Matrii Sulfas Exsiccatus, the Radix Astragali, Radix Codonopsis, Poria are mixed
Crush after conjunction, cross 24～80 mesh sieves, obtain coarse powder；
S3：Coarse powder is continued under cryogenic to crush, in the crushing process of coarse powder, Flos Lonicerae, Fructus Forsythiae, anise is mixed successively
Fructus Foeniculi and Fructus Foeniculi are crushed together with the coarse powder obtained by step S2, cross 200～400 mesh sieves, obtain fine powder after crushing；
S4：Fine powder obtained by step S3 is loaded into mix homogeneously in mixer, subpackage is carried out, is packed, is obtained final product Chinese powder medicine.
4. preparation method according to claim 3, it is characterised in that cryogenic conditions described in step S3 are 0～4 DEG C.
5. preparation method according to claim 3, it is characterised in that cryogenic conditions are by pulverizer described in step S3
Low-temperature cooling water is passed through in shell and is realized.
6. preparation method according to claim 3, it is characterised in that in step S3, in the crushing process of coarse powder, successively
Mix Flos Lonicerae, Fructus Forsythiae, Fructus Anisi Stellati and Fructus Foeniculi to crush together with the coarse powder obtained by step S2, after crushing, cross 300 mesh sieves.
7. preparation method according to claim 3, it is characterised in that the Chinese powder medicine is yellow to filemot powder
End；Gas perfume, bitter in the mouth, micro-puckery；Thin layer differentiates to detect Rhizoma Coptidis, Fructus Gardeniae, Radix Scutellariae, Radix Et Rhizoma Rhei, chlorogenic acid；Moisture≤10%；Outward
See the uniformity and uniform color and luster should be presented, without decorative pattern, mottle.
8. a kind of Chinese powder medicine for pig circular ring virus 2 and/or reproductive and respiratory syndrome prepare for prevent or treat pig circular ring virus 2 and/or
Application in the medicine of reproductive and respiratory syndrome.
9. application according to claim 8, it is characterised in that
When the medicine for being used to treating pig circular ring virus 2 and/or reproductive and respiratory syndrome is prepared, the using dosage of the Chinese powder medicine is：
1. the Chinese powder medicine of 3.5kg～4.5kg, free choice feeding is added to be used in conjunction 7～14 days in water per ton or feedstuff；Preferably,
4kg is added in water per ton or feedstuff；
Or 2. Chinese powder medicine is mixed homogeneously with feedstuff according to being the ratio of 0.2g/kg～0.4g/kg with the weight ratio of pig, it is interior
Clothes, daily 2 times, are used in conjunction 7～14 days.
10. application according to claim 8, it is characterised in that
When the medicine for being used to preventing pig circular ring virus 2 and/or reproductive and respiratory syndrome is prepared, the using dosage of the Chinese powder medicine is：
1. the Chinese powder medicine of 1.5kg～2.5kg is added in water per ton or feedstuff, free choice feeding is continuous to feed 4 weeks；
Or 2. the total of the Chinese powder medicine that whole day need to be fed is calculated according to the Chinese powder medicine that 1.5kg～2.5kg is added in feedstuff per ton
Amount, is added into a small amount of feedstuff and disposably feeds, continuous to feed 4 weeks.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611198677.6A CN106511570A (en) | 2016-12-22 | 2016-12-22 | Herbal powder used for porcine circovirus and/or porcine reproductive and respiratory syndrome, and preparation method and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611198677.6A CN106511570A (en) | 2016-12-22 | 2016-12-22 | Herbal powder used for porcine circovirus and/or porcine reproductive and respiratory syndrome, and preparation method and application thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107348157A (en) * | 2017-08-25 | 2017-11-17 | 贵州三人行食品开发有限公司 | A kind of live pig pandemic epidemic-prevention fodder and preparation method thereof |
| CN109106792A (en) * | 2018-10-19 | 2019-01-01 | 河南省帝方生物制药有限公司 | A kind of compound Chinese medicinal preparation and preparation method thereof inhibiting blue otopathy poison |
| CN109528852A (en) * | 2019-01-31 | 2019-03-29 | 江苏农牧科技职业学院 | A kind of Chinese medicine composition and preparation method thereof for treating young pig blue-ear disease |
| CN109528853A (en) * | 2019-01-31 | 2019-03-29 | 江苏农牧科技职业学院 | A kind of Chinese medicine composition and preparation method thereof for treating female pig blue-ear disease |
| CN112656942A (en) * | 2021-03-09 | 2021-04-16 | 新乡市和协动物药业有限公司 | Biological traditional Chinese medicine compound preparation for preventing and treating porcine reproductive and respiratory syndrome and circovirus and application |
| CN113616726A (en) * | 2021-07-17 | 2021-11-09 | 焦作天道盛世生物科技有限公司 | A natural plant material composition for health promotion of porcine reproductive and respiratory syndrome and its preparation method |
-
2016
- 2016-12-22 CN CN201611198677.6A patent/CN106511570A/en active Pending
Non-Patent Citations (5)
| Title |
|---|
| 小舟: "蓝耳病怎么办", 《WWW.1866.TV/NEWS/69481》 * |
| 张洪培: "中药复方对蓝耳和圆环病毒的清除试验", 《中兽医学杂志》 * |
| 朱晓薇: "《中药药剂学》", 31 May 2015 * |
| 网络: "蓝耳病，圆环病毒病", 《WWW.PIG66.COM/SY/2015/16140647.HTML》 * |
| 谨言: "用中药治疗常见猪病总结", 《WWW.DOC88.COM/P-416778139764.HTML》 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107348157A (en) * | 2017-08-25 | 2017-11-17 | 贵州三人行食品开发有限公司 | A kind of live pig pandemic epidemic-prevention fodder and preparation method thereof |
| CN109106792A (en) * | 2018-10-19 | 2019-01-01 | 河南省帝方生物制药有限公司 | A kind of compound Chinese medicinal preparation and preparation method thereof inhibiting blue otopathy poison |
| CN109106792B (en) * | 2018-10-19 | 2021-05-25 | 河南省帝一方生物制药有限公司 | Traditional Chinese medicine compound preparation for inhibiting blue ear virus and preparation method thereof |
| CN109528852A (en) * | 2019-01-31 | 2019-03-29 | 江苏农牧科技职业学院 | A kind of Chinese medicine composition and preparation method thereof for treating young pig blue-ear disease |
| CN109528853A (en) * | 2019-01-31 | 2019-03-29 | 江苏农牧科技职业学院 | A kind of Chinese medicine composition and preparation method thereof for treating female pig blue-ear disease |
| CN112656942A (en) * | 2021-03-09 | 2021-04-16 | 新乡市和协动物药业有限公司 | Biological traditional Chinese medicine compound preparation for preventing and treating porcine reproductive and respiratory syndrome and circovirus and application |
| CN113616726A (en) * | 2021-07-17 | 2021-11-09 | 焦作天道盛世生物科技有限公司 | A natural plant material composition for health promotion of porcine reproductive and respiratory syndrome and its preparation method |
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