CN106511135B - A kind of whitening compound essential oil and preparation method thereof - Google Patents
A kind of whitening compound essential oil and preparation method thereof Download PDFInfo
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- CN106511135B CN106511135B CN201611197606.4A CN201611197606A CN106511135B CN 106511135 B CN106511135 B CN 106511135B CN 201611197606 A CN201611197606 A CN 201611197606A CN 106511135 B CN106511135 B CN 106511135B
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- parts
- oil
- essential oil
- whitening
- saualane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Abstract
The invention proposes a kind of whitening compound essential oils and preparation method thereof, it is calculated by mass by 5-20 parts of Lavender, 0.5-5 parts of flores aurantii essential oil, 0.2-2 parts of Rosa Damascana, 0.5-5 parts of Cananga odorata quintessence oil, 40% 0.1-1.2 parts of glabridin, 0.5-2.5 parts of stearyl alcohol glycyrrhetin acid esters, 1-8 parts of saualane and 70-90 parts of base oil are prepared, complete one aspect of the present invention uses Pure natural plant essential oil and pure natural plant extract completely, it is mostly small-molecule substance good penetrability using essential oil, the speed of absorption of human body essential oil is especially fast, the whitening factor is set to reach cell deep layer rapidly under the guidance and effect of essential oil, it finds and locks melanin production enzyme, inhibit its activity, to make the melanin production ability rapid decrease of skin cell, the colour of skin just has bright in a short time Aobvious whitening, and it is safe and non-stimulating, it has no toxic side effect, is suitable for being used for a long time, on the other hand joined light grass Gan Ding, saualane and another whitening, sun-proof and nti-freckle ingredient glycyrrhetin acid esters by a certain percentage, play synergistic effect, further enhance whitening effect.
Description
Technical field
The present invention relates to skin-protection product fields more particularly to a kind of whitening compound essential oil and preparation method thereof.
Background technique
The preparation process of plants essential oil is environmentally protective, Atoxic itself, and plants essential oil is the extraction distinctive fragrance of plant
Substance is taken from herbal flower, leaf, root, bark, fruit, seed, resin etc. with steam distillation, extrusion, cold soaking
Method or solvent extraction method refine the volatile flavor of extraction.
Whitening compound essential oil on the market mostly forms or is added single whitening composition by several essential oils at present, and whitening effect has
Limit.And absorption and the effect hair for causing in the preparation of essential oil there are some problems and its finished dosage form capable of being made to reach maximum efficiency
The shortcomings that waving.
Based on problem above, optimal whitening compound essential oil formula combination and ratio, another party on the one hand how are filtered out
How face sets about from the preparation process of whitening compound essential oil, further improves skin cell deep layer to the assimilation effect of essential oil,
Inhibit the activity of melanin.
Summary of the invention
Goal of the invention: in order to overcome the problems of the prior art, the invention proposes one kind to have replenishing water and preserving moisture, whitening anti-
The whitening compound essential oil and preparation method thereof for function of wrinkling.
Technical solution: in order to solve the above-mentioned technical problem, the technical scheme adopted by the invention is as follows: a kind of whitening compound essence
Oil includes following component by weight:
5-20 parts of Lavender
0.5-5 parts of flores aurantii essential oil
0.2-2 parts of Rosa Damascana
0.5-5 parts of Cananga odorata quintessence oil
40% 0.1-1.2 parts of glabridin
0.5-2.5 parts of stearyl alcohol glycyrrhetin acid esters
1-8 parts of saualane
70-90 parts of base oil.
It more preferably, by weight include the preferred of following component the present invention also provides a kind of whitening compound essential oil
Formula:
10 parts of Lavender
1.5 parts of flores aurantii essential oil
1.5 parts of Cananga odorata quintessence oil
1 part of Rosa Damascana
40% 0.5 part of glabridin
1 part of stearyl alcohol glycyrrhetin acid esters
5 parts of saualane
80 parts of base oil.
More preferably, the base oil is selected from He Heba oil, rose hip oil, grape seed oil, Sweet Almond Oil, wheat embryo
One of oil, olive oil are a variety of.
Further, the base oil is grape seed oil.
The invention also discloses above-mentioned a kind of compound skin-whitening essential oils and preparation method thereof, include the following steps:
(1) various raw material for standby are weighed first, in accordance with formula aequum;
(2) take 40% glabridin, stearyl alcohol glycyrrhetin acid esters stirring and dissolving in Lavender;Until completely dissolved
Sequentially add flores aurantii essential oil, Rosa Damascana and Cananga odorata quintessence oil stir mixture A is spare;
(3) it takes in saualane stirring plus base oil, mixture B is obtained after mixing completely, the mixing for taking step (2) spare
Object A is slowly added to mixture B, stir to get.
Lavender can be clearing heat and detoxicating, cleaning skin, controls oil, freckle removing and whitening, the tender skin of anti-wrinkle, eye haustra -dsipelling are black
Eyelet may additionally facilitate the skin-protecting functions such as regeneration of damaged tissue recovery, have beauty to human body, pressure of releiving, the effects of relaxing one's muscles.
Flores aurantii essential oil is to be rich in a variety of whitening active ingredients using the wax little Hua of the white on bitter mandarin tree as raw material,
The fragrant factor it is easypro lead under, the melanin formed in skin can be exported layer by layer, and with the metabolism of aging cutin and
It excludes, melanin do not depositing, and skin is gradually pale while can also exclude the turbidity assembled in skin and generate because of pollution
Harmful substance makes skin that zero burden, the state of zero pressure be presented.Effect of flores aurantii essential oil maximum just on the skin, enhances cell
Vigor helps cytothesis, increases skin elasticity;Whitening, moisturizing, light spot, nourishing is crease-resistant, restores delicate, is suitble to stemness, sensitivity
And other problems skin, especially spiral helicine varication, scar and striae of pregnancy;When according to X-ray, it is also used to protection skin
Skin.
Rosa Damascana has good beautifying skin-protection function, supports outer Kohakuhi within energy, melanin is promoted to decompose, improve
Dry skin restores skin elasticity, allows women to possess healthy skin pale, full of elasticity, is the virtue of optimum female health
Essential oil.
Glabridin is a kind of natural material that whitening effect is very outstanding, can only be extracted from rare glycyrrhiza glabra
It arrives.The IC50 value for inhibiting melanin by detection, it is found that the whitening effect of glabridin is higher by 232 times than vitamin C.Meanwhile
Glabridin also has effects that anti-inflammatory, oxidation resistant, and is tested by U.S. FDA, is the peace that stimulation will not be caused to skin
Full ingredient.
Stearyl alcohol glycyrrhetin acid esters has the function of whitening, sun-proof and nti-freckle, by inhibiting tyrosinase and dopachrome
Interconvertible enzyme TRP) activity, hinder 5,6- dihydroindole polymerization, the formation of melanin is prevented with this, reaches whitening effect.
For saualane closest to a kind of lipid of human sebaceous, affinity is strong, and can melt with the sebum film of mankind itself is one
Body forms one layer of natural barrier in skin surface;It can also inhibit the peroxidating of skin lipid, can effectively infiltrate through skin, and
Promote the proliferation of skin base cell, to delay skin aging, improving and eliminating chloasma has apparent physiologic effect, also may be used
Skin pore is opened, blood microcirculation is promoted, promotes the metabolism of cell, damaged cell is repaired in help.
The utility model has the advantages that a kind of whitening compound essential oil provided by the invention and preparation method thereof, calculated by mass by lavender
5-20 parts of essential oil, 0.5-5 parts of flores aurantii essential oil, 0.2-2 parts of Rosa Damascana, 0.1-1.2 parts of 40% glabridin, glycyrrhetin acid esters
0.5-2.5 parts, 1-8 parts of saualane and 70-90 parts of base oil are prepared, and complete one aspect of the present invention uses pure natural plant completely
Object essential oil and pure natural plant extract, are mostly small-molecule substance good penetrabilities using essential oil, and the speed of absorption of human body essential oil is special
It is not fast, so that the whitening factor is reached cell deep layer rapidly under the guidance and effect of essential oil, find and lock melanin production enzyme, presses down
Its activity is made, to make the melanin production ability rapid decrease of skin cell, the colour of skin just has apparent whitening in a short time,
And it is safe and non-stimulating, it has no toxic side effect, is suitable for being used for a long time, on the other hand joined light grass Gan Ding, saualane by a certain percentage
And another whitening, sun-proof and nti-freckle ingredient stearyl alcohol glycyrrhetin acid esters, synergistic effect is played, whitening effect is further enhanced
Fruit.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail:
Embodiment 1- embodiment 4 by being prepared into a kind of whitening compound essential oil according to the formula in table 1:
Table 1: whitening compound essential oil embodiment 1-4 formula unit: kg
Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | |
Lavender | 10 | 5 | 15 | 20 |
Flores aurantii essential oil | 1.5 | 0.5 | 3 | 5 |
Rosa Damascana | 1 | 0.2 | 1 | 2 |
Cananga odorata quintessence oil | 1.5 | 0.5 | 3 | 5 |
40% glabridin | 0.5 | 0.1 | 1 | 1 |
Stearyl alcohol glycyrrhetin acid esters | 1 | 0.5 | 2 | 2 |
Saualane | 5 | 1 | 3 | 8 |
Base oil | 80 (grape seed oils) | 90 (Sweet Almond Oils) | 90 (olive oil) | 70 (rose hip oils) |
Comparative example test sample is prepared by formula as below:
Comparative example 1: 10 parts of Lavender, 1.5 parts of flores aurantii essential oil, 1 part of Rosa Damascana, 1.5 parts of Cananga odorata quintessence oil, grape pip
80 parts of oil.
Comparative example 2: 10 parts of Lavender, 1.5 parts of flores aurantii essential oil, 1 part of Rosa Damascana, 1.5 parts of Cananga odorata quintessence oil, 40% light
Licoricidin, 5 parts of saualanes, 80 parts of grape seed oil.(addition glabridin and saualane)
Comparative example 3: 10 parts of Lavender, 1.5 parts of flores aurantii essential oil, 1 part of Rosa Damascana, 1.5 parts of Cananga odorata quintessence oil, 1 part it is hard
Resin acid glycyrrhetin acid esters, 5 parts of saualanes, 80 parts of grape seed oil.(addition stearic acid glycyrrhetin acid esters and saualane)
The formula of selection example 1 is tested with comparative example test sample:
Study subject selects 200 female volunteers, is randomly divided into an experimental group, three control groups.
Wherein experimental group study subject uses the whitening compound essential oil an of embodiment 1, application method daily are as follows: cleaning face
It after portion's skin, dries, essential oil is applied on facial skin with hand.Control group 1 daily using 1 compound essential oil of comparative example,
Control group 2 uses 3 compound essential oil of comparative example, user using 2 compound essential oil of comparative example, control group 3 daily daily
Method is identical.Four groups of study subjects do not use other whitening products dduring test.
Test and evaluation method: determination of the environment is test environment temperature (20 ± 1) DEG C, and humidity (50 ± 5) % is averaged
Value.Test method is melanin content in measurement human skin, is evaluated the white-skinned face function of compound essential oil, and measurement numerical value is got over
Height illustrates that melanin content is higher in skin.It is specific using skin pigment instrument in answering using embodiment 1 and comparative example test sample
1 day and two kinds of continuous use measure the melanin content of its skin of face after essential oil 28 days before square essential oil, every group take 50 it is tested
The test result average value of object, melanin reduced rate are calculated as follows.Melanin reduced rate is higher, illustrates whitening
Effect is more obvious.
Melanin reduced rate=(contained using melanin after 1 day before essential oil melanin content-continuous use essential oil 28 days
Amount) ÷ uses 1 day before essential oil melanin content × 100%.
2 experimental group of table and control group compare
Melanin reduced rate (%) | |
Experimental group | 78.9 |
Control group 1 | 13.4 |
Control group 2 | 24.6 |
Control group 3 | 22.3 |
As shown in Table 2: control group 2 adds 40% glabridin centainly matched, glycyrrhetin acid esters, control group in essential oil
3 add the stearic acid glycyrrhetin acid esters and saualane centainly matched in essential oil, and whitening effect is obviously than several essential oil lists
The 1 melanin reduced rate of control group being solely used in mixed way is high, and whitening effect is enhanced.
And embodiment 1 compared with comparative example test sample 1-3 for, by 40% glabridin, stearic acid glycyrrhetin acid esters, saualane
It is added together and plays synergistic action effect ratio to be added separately to melanin reduced rate high, whitening effect enhancing is more preferable.
It should be pointed out that the above specific embodiment is only illustrative of the invention and is not intended to limit the scope of the invention,
After having read the present invention, those skilled in the art fall within power appended by the application to the modification of various equivalent forms of the invention
Benefit requires limited range.
Claims (4)
1. a kind of whitening compound essential oil, it is characterised in that by weight include following component:
5-20 parts of Lavender
0.5-5 parts of flores aurantii essential oil
0.2-2 parts of Rosa Damascana
0.5-5 parts of Cananga odorata quintessence oil
40% 0.1-1.2 parts of glabridin
0.5-2.5 parts of stearyl alcohol glycyrrhetin acid esters
1-8 parts of saualane
70-90 parts of base oil;The base oil is selected from SIMMONDSIA CHINENSIS SEED OIL, rose hip oil, grape seed oil, Sweet Almond Oil, wheat embryo
One of oil, olive oil are a variety of.
2. whitening compound essential oil according to claim 1, it is characterised in that by weight include following component:
10 parts of Lavender
1.5 parts of flores aurantii essential oil
1 part of Rosa Damascana
1.5 parts of Cananga odorata quintessence oil
40% 0.5 part of glabridin
1 part of stearyl alcohol glycyrrhetin acid esters
5 parts of saualane
80 parts of base oil.
3. whitening compound essential oil according to claim 1, it is characterised in that: the base oil is grape seed oil.
4. the preparation method of whitening compound essential oil as described in claim 1, it is characterised in that include the following steps:
(1) various raw material for standby are weighed first, in accordance with formula aequum;
(2) take 40% glabridin, stearyl alcohol glycyrrhetin acid esters stirring and dissolving in Lavender;Until completely dissolved successively
Flores aurantii essential oil is added, Rosa Damascana and Cananga odorata quintessence oil stir mixture A is spare;
(3) it takes saualane stirring to be added in base oil, mixture B is obtained after mixing completely, the mixture for taking step (2) spare
A is slowly added to mixture B, stir to get.
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CN107441002A (en) * | 2017-09-25 | 2017-12-08 | 湖南爱瑞西诗生命科技有限公司 | A kind of essential oils |
CN108066183A (en) * | 2017-12-27 | 2018-05-25 | 广州市澳键丰泽生物科技股份有限公司 | Eye glue preparation containing plants essential oil and its preparation method and application |
CN108685768A (en) * | 2018-07-23 | 2018-10-23 | 西安花实化妆品有限公司 | A kind of compound essential oil of freckle removing and whitening and preparation method thereof |
CN109464308B (en) * | 2018-11-15 | 2021-06-04 | 广州天芝丽实业有限公司 | Essential oil composition with blue light resisting and skin caring effects and application thereof |
CN110075014A (en) * | 2019-05-31 | 2019-08-02 | 广东盛美化妆品有限公司 | A kind of Whitening, spot essential oils and preparation method thereof |
CN112370404B (en) * | 2020-11-25 | 2022-09-16 | 桂林理工大学 | Moisturizing and whitening composition, and preparation method and application thereof |
CN112370380B (en) * | 2020-11-30 | 2022-11-18 | 李慧芬 | Rose skin-brightening and face-cleaning essential oil, and preparation method and application thereof |
CN112755083A (en) * | 2021-01-22 | 2021-05-07 | 广州顺倬能源科技有限公司 | Emu camphor essential oil for promoting skin repair and preparation method thereof |
CN113730292A (en) * | 2021-09-15 | 2021-12-03 | 深圳市靓丽人生化妆品有限公司 | Whitening essence and preparation method and application thereof |
CN115154372A (en) * | 2022-07-18 | 2022-10-11 | 中国医学科学院药用植物研究所 | Compound essential oil with compound effect and preparation method and application thereof |
CN115531229A (en) * | 2022-11-08 | 2022-12-30 | 浙江海心智惠科技有限公司 | Preparation method of skin-moistening plant essential oil |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103006489A (en) * | 2011-09-22 | 2013-04-03 | 朱勤舟 | Whitening compound essential oil |
CN103361181A (en) * | 2013-07-19 | 2013-10-23 | 中国医学科学院药用植物研究所海南分所 | Rose compound essential oil for resisting skin aging |
CN104116668A (en) * | 2014-06-26 | 2014-10-29 | 张少维 | Whitening essential oil |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2004196669A (en) * | 2002-12-16 | 2004-07-15 | Kose Corp | Melanocyte proliferation inhibitor and skin care preparation for external use comprising the same |
JP2011195494A (en) * | 2010-03-19 | 2011-10-06 | Pola Chemical Industries Inc | Composition containing proton pump inhibitor |
-
2016
- 2016-12-22 CN CN201611197606.4A patent/CN106511135B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103006489A (en) * | 2011-09-22 | 2013-04-03 | 朱勤舟 | Whitening compound essential oil |
CN103361181A (en) * | 2013-07-19 | 2013-10-23 | 中国医学科学院药用植物研究所海南分所 | Rose compound essential oil for resisting skin aging |
CN104116668A (en) * | 2014-06-26 | 2014-10-29 | 张少维 | Whitening essential oil |
Non-Patent Citations (1)
Title |
---|
甘草酸二钾和硬脂醇甘草亭酸酯在化妆品中的应用;陈保华等;《中国化妆品》;20141231(第7期);第302页 * |
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