KR20190094913A - Composition for preventing hair loss or reinforcing scalp comprising natural extract - Google Patents

Abstract

The present invention relates to a hair loss preventing or scalp reinforcing composition comprising a natural extract as an active ingredient. A natural extract composition comprising a green tea extract, Houttuynia cordata extract, Saccharina japonica extract, black soybean extract, silk amino acids, biotin and essential oils has the effect of inhibiting sebum of the scalp, preventing hair loss, improving the scalp and reinforcing the hair condition. Therefore, the natural extract composition of the present invention having the effects can be usefully used for the development of a comprehensive functional product capable of improving the scalp condition, such as preventing hair loss, improving hair condition, preventing sebum and alleviating inflammation.

Description

Composition for preventing hair loss or reinforcing scalp comprising natural extract as an active ingredient {composition for preventing hair loss or reinforcing scalp comprising natural extract}

The present invention relates to a hair loss preventing or scalp strengthening composition comprising a natural extract as an active ingredient.

The human hair is about 100,000 to 150,000 pieces, each hair has a different cycle and grow and drop out through the anagen, catagen, telogen. This cycle is repeated over three to six years, with the result that on average 50-100 hairs fall out normally. Generally, the term alopecia means that the hair growth rate of the growth phase is shortened among these cycles, and the number of hairs of the degenerative or resting phase increases, so that the number of abnormal hair dropouts increases.

The causes of hair loss are known to be excessive secretion of male hormones, seborrheic scalp, stress, obesity, peroxide, bacteria, reduced scalp function, malnutrition, side effects caused by drugs, genetic factors. In addition, it is known that the scalp and hair are damaged by irritation of the scalp and hair due to excessive shampooing, drying, hair styling, and the like, and the natural moisturizing component of the scalp by chemical cleaning ingredients is removed. However, to date, no clear cause of hair loss is known, and in recent years, a growing number of people are suffering from hair loss due to changes in diet and stress caused by social conditions. Population is also increasing.

Accordingly, research has been conducted on compositions capable of preventing abnormal symptoms of various scalp and hair, including hair loss, and improving the condition of the scalp and hair. However, the existing scalp and hair-related products are often the main ingredient is a chemical, causing many side effects on the scalp, mostly to improve the function by working on either the scalp or hair. Therefore, it is a comprehensive functional product that is not only safe for the living body and easy to use, but also has high stability in terms of formulation, and improves the hair condition including hair loss prevention and hair growth promotion, as well as anti-dandruff and inflammation reduction. The development of is urgently needed.

Republic of Korea Patent No. 10-1800956 (Nov. 17, 2017 registration)

It is an object of the present invention to provide a composition for preventing hair loss or strengthening the scalp comprising a natural extract as an active ingredient.

In order to achieve the above object, the present invention is based on a total of 100 parts by weight of the composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, Cosmetic composition, pharmaceutical composition for preventing hair loss or improving scalp condition comprising 2 to 6 parts by weight of black bean extract, 2 to 6 parts by weight of biotin, 12 to 16 parts by weight of silkamino acid, and 0.1 to 0.8 parts by weight of essential oil as active ingredients. Provide a health food composition.

Natural extract composition comprising green tea extract, Echochocho extract, kelp extract, black soybean extract, silk amino acid, biotin and essential oil according to the present invention inhibits sebum of the scalp, prevents hair loss, improves scalp and enhances hair condition It has an effect to make. Therefore, the natural extract composition of the present invention having the above effect can be usefully used for the development of a comprehensive functional product capable of improving the scalp condition, such as preventing hair loss and improving hair condition, preventing sebum and inflammation.

Figure 1 shows in sequence the manufacturing process of the product for preventing hair loss and scalp enhancement comprising a natural extract according to the present invention as an active ingredient.
Figure 2 compares the sebum improvement effect before and after using the product by applying the product to the scalp.
Figure 3 compares the degree of hair loss before and after use by applying the product to the scalp after shampooing.

The inventors of the present invention, based on the bamboo extract, the addition of green tea extract, eochocho extract, kelp extract, black bean extract, silkamino acid, biotin, essential oils, biotin and glycerin in various blending ratios to select the most suitable blending ratio In addition, the natural extract composition was confirmed to exhibit the effect of inhibiting sebum of the scalp and improving hair loss, and completed the present invention.

Green tea is steamed or steamed from young leaves of tea trees to suppress the action of enzymes, and is dried. It contains high amounts of physiologically active polyphenols, catechin and tannin, as well as caffeine, vitamins and many inorganic substances. It contains a large amount of salt and is widely used all over the world. The oxygen we breathe produces free radicals in the process of making energy, and it is important that the free radicals be removed quickly before they attack the cells, because they attack different parts of the cell. Green tea extract is known to react with free radicals that are harmful to our body to remove excess free radicals and to act as an antioxidant. In addition, catechins, the main component of green tea, have strong sterilizing ability against adult diseases, acquired immunodeficiency syndrome, viruses and tooth decay bacteria, and are used as raw materials for cosmetics such as tooth decay toothpaste and deodorant. In addition, since caffeine in coffee has chlorogenic acid as its main ingredient and there is no catechin in green tea, it is absorbed directly into the body and causes strong caffeine activity and causes arteriosclerosis and heart disease, whereas green tea caffeine is a catechin that lowers blood cholesterol and The same action does not occur because it works together. Therefore, green tea may increase the antioxidant effect and induce hair growth.

Eochochocho contains the most abundant querchitrin among the flavonoids. Cuerchithrin dilates blood vessels to act as a diuretic, constipation and elimination of stool, and by strengthening capillaries, blood pressure is maintained at an appropriate level to improve blood flow. Therefore, Eoseongcho provides enough nutrition to the scalp and removes toxins and various wastes accumulated in the scalp to strengthen scalp cells, and helps hair loss by helping to generate and activate hair cells.

Kelp is a seaweed belonging to the brown algae, calcium is abundant in the kelp is a major component of bone and its composition, and also contains abundant magnesium to enhance calcium activity in the body is effective in strengthening bone and it. Kelp contains protein, vitamins, iodine, zinc, sulfur, calcium, iron, etc., which make up hair, and oxo, a component that promotes hair growth, may also be effective in treating hair loss.

Black soybean contains not only high-quality protein but also various vitamins as well as cysteine, phytoestrogens, and isoflavones, which are the main constituents of hair. Can be induced.

Silkamino acid is one of the natural amino acids obtained from cocoon, and consists of 8 essential amino acids and 10 non-essential amino acids.These amino acids include glycine, alanine, serine, tyrosine ( Tyrosine, Valine, Asparagine acid, Glutamine acid, Threonine, Thsoleon, Isoleucine, Phenylalanine, Leucine, Arginine, Lysine Cysteine, Proline, Histidine, Tryptophan, Methionine. Silkamino acids are known to have skin regeneration, hemostatic and antipyretic effects, and are well absorbed by the skin, which can help to restore the scalp and damaged hair.

Biotin is a water-soluble vitamin that is part of the vitamin B complex and is a key nutrient for the body's metabolism, nerves, digestion, and cardiovascular function. Biotin acts as the body's coenzyme for the metabolism of fatty acids, amino acids and glucose, helps metabolize proteins, improves the scalp and stimulates hair follicle tissue to promote new hair production.

Menthol contained in peppermint oil can reduce scalp heat with antibacterial and cooling effect, tea tree oil has sebum control effect to prevent seborrheic scalp infection, and rosemary oil promotes blood circulation of scalp This can activate hair follicle cells and promote hair production.

The present invention is based on 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to 6 parts by weight of black bean extract It provides a cosmetic composition for preventing hair loss or improving the scalp state, comprising 2 to 6 parts by weight of biotin, 12 to 16 parts by weight of silkamino acid, and 0.1 to 0.8 parts by weight of essential oil as an active ingredient.

The essential oil may be any one or more selected from the group consisting of peppermint oil, tea tree oil, rosemary oil, and rims oil, but is not limited thereto.

The peppermint oil, tea tree oil, rosemary oil and rims oil may be included in a weight ratio of 3: 3: 3: 1, but are not limited thereto.

The composition may further comprise a moisturizer and a solubilizer, the moisturizer being glycerin, butylene glycol, dipropylene glycol, sodium hyaluronate, betaine, trehalose, propylene glycol, sodium lactate, sorbitol and squalene It may be selected from the group consisting of, the solubilizer may be selected from the group consisting of olive liquid, HCO60, HCO40, solubilizer, polysorbate and solusol, but is not limited thereto.

The moisturizing agent is glycerin, the solubilizer may be preferably olive liquid.

The composition can prevent hair loss, inhibit sebum or improve hair condition.

The composition includes hair tonic, hair conditioner, hair essence, hair lotion, hair nutrition lotion, hair shampoo, hair rinse, hair treatment, hair cream, hair nourishment cream, hair moisturizer cream, hair massage cream, hair wax, hair aerosol, Hair Pack, Hair Nutrition Pack, Hair Soap, Hair Cleansing Foam, Hair Oil, Hair Dryer, Hair Preservative, Hair Dye, Hair Wave Agent, Hair Bleach, Hair Gel, Hair Glaze, Hair Dresser, Hair Lacquer, Hair Moisturizer, Hair It may be, but is not limited to, a formulation selected from the group consisting of mousse and hairspray.

When the composition of the present invention is a cosmetic composition, the cosmetic composition may include, in addition to the active ingredient, conventional auxiliaries such as stabilizers, solubilizers, vitamins, pigments and flavors, and carriers. In addition, the cosmetic composition may further include a skin absorption enhancer to enhance the effect.

The formulation of the cosmetic composition may be prepared in any formulation conventionally prepared in the art, for example, the cosmetic composition may be a lotion, latex, skin, toner, lotion, essence, sunscreen, cream, makeup base, foundation , Powders, packs, gels, shampoos, rinses, sprays, makeup removers and cleansers, etc., but are not limited thereto.

When the formulation is a paste, cream or gel, animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as a carrier component. .

If the formulation is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used, in particular in the case of a spray additionally chlorofluorohydrocarbon, propane / butane Or propellants such as dimethyl ether.

If the formulation is a solution or emulsion, solvents, solubilizers or emulsions are used as carrier components, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1,3 Fatty acid esters of butylglycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan.

If the formulation is a suspension, liquid carrier diluents such as water, ethanol or propylene glycol, suspensions such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol esters and polyoxyethylene sorbitan esters, microcrystalline cellulose , Aluminum metahydroxy, bentonite, agar or tracant and the like can be used.

In addition, the present invention with respect to 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to black soybean extract It provides a pharmaceutical composition for preventing hair loss or improving scalp condition comprising 6 parts by weight, 2 to 6 parts by weight of biotin, 12 to 16 parts by weight of silkamino acid, and 0.1 to 0.8 parts by weight of essential oil as an active ingredient.

The essential oil may be any one or more selected from the group consisting of peppermint oil, tea tree oil, rosemary oil, and rims oil, but is not limited thereto.

When the composition of the present invention is a pharmaceutical composition, for administration, it may include a pharmaceutically acceptable carrier, excipient or diluent in addition to the active ingredient described above. The carrier, excipient and diluent may include lactose, dextrose, sucrose, sorbitol, mannitol, xylitol, erythritol, maltitol, starch, acacia rubber, alginate, gelatin, calcium phosphate, calcium silicate, cellulose, methyl cellulose, microcrystalline cellulose, Polyvinylpyrrolidone, water, methylhydroxybenzoate, propylhydroxybenzoate, talc, magnesium stearate and mineral oil.

The pharmaceutical compositions of the present invention may be formulated in the form of powders, granules, tablets, capsules, suspensions, emulsions, syrups, aerosols, oral formulations, external preparations, suppositories, or sterile injectable solutions according to conventional methods. . In detail, when formulated, it may be prepared by using diluents or excipients such as fillers, weights, binders, wetting agents, disintegrating agents, and surfactants which are commonly used. Solid preparations for oral administration include, but are not limited to, tablets, pills, powders, granules, capsules, and the like. Such solid preparations may be prepared by mixing at least one excipient such as starch, calcium carbonate, sucrose, lactose, gelatin and the like in addition to the active ingredient. In addition to simple excipients, lubricants such as magnesium stearate, talc can also be used. It may be prepared by adding various excipients such as humectants, sweeteners, fragrances, preservatives and the like in addition to liquid oral liquids or liquid paraffin for oral use. Formulations for parenteral administration include sterile aqueous solutions, non-aqueous solvents, suspensions, emulsions, lyophilized formulations and tasks. As the non-aqueous solvent and suspending agent, propylene glycol, polyethylene glycol, vegetable oils such as olive oil, injectable esters such as ethyl oleate, and the like can be used. As the base of the suppository, utopsol, macrosol, tween 61, cacao butter, laurin butter, glycerogelatin and the like can be used.

Suitable dosages of the pharmaceutical compositions of the present invention vary depending on the condition and weight of the patient, the severity of the disease, the form of the drug, and the time, but can be appropriately selected by those skilled in the art, and therefore the daily dosage of the composition is preferably It is 0.001 mg / kg to 50 mg / kg, it can be administered once or divided into several times as needed.

In addition, the present invention with respect to 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to black soybean extract It provides a health food composition for preventing hair loss or improving the scalp condition comprising 6 parts by weight, 2 to 6 parts by weight of biotin, 12 to 16 parts by weight of silkamino acid, and 0.1 to 0.8 parts by weight of essential oil as an active ingredient.

The essential oil may be any one or more selected from the group consisting of peppermint oil, tea tree oil, rosemary oil, and rims oil, but is not limited thereto.

When the composition of the present invention is a health food composition, flavors such as various nutrients, vitamins, minerals (electrolytes), synthetic flavors and natural flavors, coloring and neutralizing agents (such as cheese, chocolate), pectic acid and salts thereof , Alginic acid and salts thereof, organic acids, protective colloidal thickeners, pH adjusters, stabilizers, preservatives, glycerin, alcohols, carbonation agents used in carbonated drinks and the like. Others may contain pulp for the production of natural fruit juices, synthetic fruit juices and vegetable drinks. These components can be used independently or in combination. In addition, the health food composition may be in the form of any one of meat, sausage, bread, chocolate, candy, snacks, confectionary, pizza, ramen, gum, ice cream, soup, beverage, tea, functional water, drink, alcohol and vitamin complex Can be.

In addition, the health food composition may further include a food additive, and the suitability as a food additive is related to the item according to the General Regulations and General Test Law of the Food Additives Code approved by the Ministry of Food and Drug Safety unless otherwise specified. Judging by the standards and standards.

Examples of the items added to the food additives, chemical synthetic products such as ketones, glycine, potassium citrate, nicotinic acid, cinnamon acid, navy dye, licorice extract, natural additives such as crystalline cellulose, high quench pigment, guar gum, L-glutamic acid Mixed preparations, such as a sodium preparation, a noodles addition alkali agent, a preservative preparation, and a tar pigment preparation, etc. are mentioned.

At this time, the composition according to the present invention to be added to food in the process of preparing a health food composition can be appropriately added or reduced the content as needed.

Hereinafter, the present invention will be described in more detail with reference to Examples. These examples are only for illustrating the present invention in more detail, it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples in accordance with the gist of the present invention. .

Example  1: Preparation of a composition containing a natural extract

Figure 1 shows in sequence the method for producing a composition containing a natural extract. First, green tea, eoseongcho, kelp and black soybeans were quantified by 250 g each, and extracted by boiling for 6 hours in 500 mL of water using an Oku extractor. Each extract was concentrated to a volume of 150 mL using a vacuum depressurizer. The concentrate was filtered through filter paper to remove impurities. 0.4 g of biotin was quantified and added to a 50 mL volumetric flask, dissolved, and the supernatant was used. To enhance the fragrance and performance of the product, peppermint oil, tea tree oil and rosemary oil were used as essential oils. Based on bamboo extract, glycerin was used as a moisturizer, and olive liquid was used as a solubilizer to mix the water layer and the oil layer. Silkamino acids were used to aid in the absorption of the composition. The composition was placed in a container to complete the product.

The product was prepared by differently blending the content of each component, and the product was evaluated and analyzed to determine the optimum blending ratio.

Example 2 Analysis of Effect of Product on Mixing Ratio of Each Component

Using the components of Example 1, as shown in Table 1 below, four products were completed at various mixing ratios.

As a result of applying each product to the scalp, the refreshment was in the order of 3> 1> 4> 2. Compared with oil refreshment, the same amount of oil was added to product 1 and 3, but product 1, which contained more solubilizers and additives, was less.

The feeling of use was in the order of 4> 3> 2> 1, and the higher the content of the bamboo extract, which is the basic base, the less stickiness, so there was less rejection.

The effect on scalp sebum was 3> 2> 4> 1. When the amount of the additive was large, the feeling was heavy and more sebum of the scalp occurred.

Based on the above results, it was determined that the compounding ratio of the third product was most suitable.

However, the product has a problem that the product is not rapidly absorbed into the scalp, to improve the absorption of the product, silk amino acid was added, and to improve dandruff symptoms and dry scalp, rims oil was added.

Using the components of Example 1 and silk amino acid, rims oil, as shown in Table 2 below, four products were completed at various mixing ratios.

In the above products, the formulation ratio of the third product was determined to be the most suitable, thus completing the product at the three formulation ratios.

Each product was applied to the scalp for 30 days to analyze sebum improvement effect. As a result, it was confirmed that the amount of sebum buried in the cotton swab after using the product as shown in FIG.

Next, after shampooing and applying the product to the scalp for 30 days to analyze the degree of hair fall, it was confirmed that the fall of the hair after using the product as shown in FIG. In addition to the hair-strengthening effects of sedation of the scalp, no side effects were found through several clinical trials.

As described above in detail certain parts of the present invention, it is apparent to those skilled in the art that these specific descriptions are merely preferred embodiments, and the scope of the present invention is not limited thereto. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.

The scope of the present invention is represented by the following claims, and it should be construed that all changes or modifications derived from the meaning and scope of the claims and their equivalents are included in the scope of the present invention.

Claims (7)

To 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to 6 parts by weight of black bean extract, biotin 2 to 6 parts by weight, 12 to 16 parts by weight of silkamino acid and 0.1 to 0.8 parts by weight of essential oils as an active ingredient hair loss prevention or cosmetic composition for improving the scalp condition. The cosmetic composition for preventing hair loss or improving scalp condition according to claim 1, wherein the essential oil is any one or more selected from the group consisting of peppermint oil, tea tree oil, rosemary oil and rims oil. The cosmetic composition for preventing hair loss or improving scalp condition according to claim 1, wherein the composition further comprises a moisturizing agent and a solubilizer. The cosmetic composition for preventing hair loss or improving scalp condition according to claim 1, wherein the composition prevents hair loss, suppresses sebum, or improves hair condition. The composition of claim 1, wherein the composition comprises hair tonic, hair conditioner, hair essence, hair lotion, hair nutrition lotion, hair shampoo, hair rinse, hair treatment, hair cream, hair nourishment cream, hair moisturizer cream, hair massage cream, Hair wax, hair aerosol, hair pack, hair nutrition pack, hair soap, hair cleansing foam, hair oil, hair dryer, hair preservative, hair dye, hair wave agent, hair bleach, hair gel, hair glaze, hair dresser, hair lacquer , Hair moisturizer, hair mousse and hair spray cosmetic composition for preventing hair loss or scalp condition characterized in that the formulation is selected from the group consisting of. To 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to 6 parts by weight of black bean extract, biotin 2 to 6 parts by weight, silk amino acid 12 to 16 parts by weight and essential oils 0.1 to 0.8 parts by weight as an active ingredient hair loss prevention or scalp condition improvement pharmaceutical composition. To 100 parts by weight of the total composition, 55 to 70 parts by weight of bamboo extract, 1 to 5 parts by weight of green tea extract, 1 to 5 parts by weight of Echochocho extract, 1 to 5 parts by weight of kelp extract, 2 to 6 parts by weight of black bean extract, biotin Health care composition for preventing hair loss or improving scalp condition comprising 2 to 6 parts by weight, 12 to 16 parts by weight of silkamino acid and 0.1 to 0.8 parts by weight of essential oil as an active ingredient.

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