CN106466414A - A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof - Google Patents
A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof Download PDFInfo
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- CN106466414A CN106466414A CN201510513195.4A CN201510513195A CN106466414A CN 106466414 A CN106466414 A CN 106466414A CN 201510513195 A CN201510513195 A CN 201510513195A CN 106466414 A CN106466414 A CN 106466414A
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Abstract
A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Caulis Clematidis Armandii 50-70 part, Semen Ciceris Arietini 15-20 part, Herba Sidae Rhombifoliae 15-20 part, Herba Bulbophylli inconspicui 8-12 part, Radix Beaumontiae Grandiflorae 8-12 part, Herba mazi japonici 5-8 part, Rubus sieboldi Blume. 5-8 part, Folium Musae 5-8 part, Bulbilus dioscoreae 5-8 part, Herba Gnaphalii Affinis 5-8 part, the mainly comprising the following steps of preparation method：Step 1, prepare Chinese medicine extract：Clean, remove impurity, mixing, extraction；Step 2, mixing：Prepare acid particles, prepare alkali grain, mixing, tabletting.A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets of the present invention, life-time service has functions that clearing away heat and promoting diuresiss, logical breast of promoting blood circulation, removing toxic substances.
Description
Technical field
The present invention relates to a kind of health body-wash articles for use, particularly a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof.
Background technology
In the traditional Chinese medical science, dipping method is one of external treatment, that is, use medicinal liquid or a kind of method containing medicinal liquid water washing bath whole body or local, and its form is varied：Have full bath and claim " liquid medicine bath "；The title again having " scalding ", " fumigation and wash method ", " demibain ", " foot bath " etc. of local bathing, especially scalds the most commonly used.
Chinese dipping, have existed since ancient times.Earliest hospital of China<52 Bingfang>In just have the dipping side controlling baby's epilepsy.《Book of Rites》In say " head has skin ulcer then to wash one's hair, and body has infectionss then to bathe ",《Huang di's Canon of Medicine》In have the record of " its be subject to exopathogen person, bathing the body with hot decoction to induce diaphoresis ", can say, the history of dipping is of long standing and well established, be laid a foundation in the Qin Dynasty, be developed in Chinese Tang, enrich in Song Ming, ripe in the Qing Dynasty.
The common dipping species in current market is broadly divided into three classes, including：Full bath, demibain, foot bath, using method is also very simply it is only necessary in the liquid medicine having dissolved to the bidet entering to mix up water temperature and the water yield or bath bucket, then steep body in water；Client progressively can experience the change of body generation during bathing.
The dipping mechanism of action in general, be medicine act on whole body flesh table, locally, affected part, and through absorb, circulation meridians blood vessels, inside reach internal organs, from outward appearance to inner essence, thus produce effect.Dipping bathing, can play dredging the meridian, activating blood circulation to dissipate blood stasis, wind dispelling cold expelling, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, regulating YIN and YANG, coordinate internal organs, current QI and blood, moisten the health maintenance effect such as foster whole body.Modern pharmacology also confirms that, can improve the content of some immunoglobulins in blood after dipping, strengthens elasticity and the vigor of skin.
Medicine used by dipping on market mostly is medicinal liquid or medicated powder, medicinal liquid or medicated powder is not portable, and composition easily runs off, and medicinal liquid that most of Chinese herbal medicine process or medicated powder cannot the sufficiently effective effective ingredient playing Chinese crude drug, loss or the waste of drug effect can be caused, and be prepared into effervescent tablet and be then easy to preserve and carry, dissolution velocity is fast, bioavailability is high, can improve clinical efficacy.
At present, the medicine of clearing away heat and promoting diuresiss or health product have much on market, but the effect of most drug is not very well, and the side effect of most drug is more, and health can be damaged, and therefore, market is badly in need of a kind of
Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof.
Content of the invention
It is an object of the invention to provide a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, life-time service has clearing away heat and promoting diuresiss, logical breast of promoting blood circulation, the effect of removing toxic substances.
The purpose of the present invention is achieved through the following technical solutions：
A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Caulis Clematidis Armandii 50-70 part, Semen Ciceris Arietini 15-20 part, Herba Sidae Rhombifoliae 15-20 part, Herba Bulbophylli inconspicui 8-12 part, Radix Beaumontiae Grandiflorae 8-12 part, Herba mazi japonici 5-8 part, Rubus sieboldi Blume. 5-8 part, Folium Musae 5-8 part, Bulbilus dioscoreae 5-8 part, Herba Gnaphalii Affinis 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Caulis Clematidis Armandii, 18 parts of Semen Ciceris Arietini, 17 parts of Herba Sidae Rhombifoliae, 12 parts of Herba Bulbophylli inconspicui, 10 parts of Radix Beaumontiae Grandiflorae, 8 parts of Herba mazi japonici, 7 parts of Rubus sieboldi Blume., 6 parts of Folium Musae, 5 parts of Bulbilus dioscoreae, 5 parts of Herba Gnaphalii Affinis.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Caulis Clematidis Armandii of selection high-quality, Semen Ciceris Arietini, Herba Sidae Rhombifoliae, Herba Bulbophylli inconspicui, Radix Beaumontiae Grandiflorae, Herba mazi japonici, Rubus sieboldi Blume., Folium Musae, Bulbilus dioscoreae, Herba Gnaphalii Affinis, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets.
In medicine：Caulis Clematidis Armandii clearing away heat and promoting diuresiss, logical breast of promoting blood circulation, control the damp and hot difficulty in urination, edema, beautiful jade disease, women's breast is difficult, menstruation apolipsis；Semen Ciceris Arietini heat-clearing and toxic substances removing；Master quenches one's thirst, hepatitis, tinea pedis；Herba Sidae Rhombifoliae clearing away heat-damp and promoting diuresis, apocenosis of invigorating blood circulation；Control influenza, flu, tonsillitiss, dysentery, enteritis, jaundice, hemorrhoidal bleeding, spit blood, carbuncle furuncle；Herba Bulbophylli inconspicui nourishing YIN and clearing away heat, preventing phlegm from forming and stopping coughing；For xeropulmonary cough, hemoptysis of pulmonary tuberculosis, pyreticosis polydipsia, tonsillitiss；Radix Beaumontiae Grandiflorae wind-damp dispelling, removing blood stasis and activating blood flow, synthetism, control fracture, traumatic injury, rheumatic lumbago and scelalgia, lumbar muscle strain, rheumatic arthritis；Herba mazi japonici antiinflammatory, removing toxic substances；Control carbuncle furuncle to swell, scald；Rubus sieboldi Blume. clearing away heat-damp and promoting diuresis, promoting blood circulation and stopping pain；Main cold, fever, dysentery, pyretic stranguria, aphtha, over-strained hemoptysis, treating swelling and pain by traumatic injury, toothache；Folium Musae heat clearing away, diuresis, removing toxic substances；Control calentura, heatstroke, tinea pedis, carbuncle pyretic toxicity, scald；The strong waist of Bulbilus dioscoreae qi-restoratives kidney tonifying；Main asthenia is won thin；Soreness of the waist and knees；Herba Gnaphalii Affinis resolving sputum, cough-relieving, cold-dispelling；Control cough with copious phlegm, asthma, cold, favism, bones and muscles pain, leucorrhea, carbuncle and ulcer
.
Beneficial effects of the present invention：One kind of the present invention
Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets, to the damp and hot difficulty in urination, edema etc.
Main
Disease
Card serves to varying degrees
Clearing away heat and promoting diuresiss, logical breast of promoting blood circulation, removing toxic substances
Effect,
There are health care, instant effect, pure natural, no side effectses.
The present invention uses the present invention through two groups of clinical verifications, one of which for treatment group, uses the present invention once daily, is within 7 days a course for the treatment of, and another group of matched group is taken
Oral Liquid Radix Panacis Quinquefolii
, daily using once, being within 7 days a course for the treatment of, every group selection outpatient 110, wherein man 55, female 55, max age 75 years old, minimal ages 24 years old, clinical manifestation is the damp and hot difficulty in urination, edema, beautiful jade disease, quenches one's thirst, hepatitis, tinea pedis
, table one is the contrasting data after taking a course for the treatment of：
Table 1 is taken two groups of courses for the treatment of of before and after and is compared (unit:People)
There were significant differences for treatment group and matched group, it will thus be seen that present invention application clinically has significant curative effect.
Specific embodiment
Embodiment 1
A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Caulis Clematidis Armandii 50-70 part, Semen Ciceris Arietini 15-20 part, Herba Sidae Rhombifoliae 15-20 part, Herba Bulbophylli inconspicui 8-12 part, Radix Beaumontiae Grandiflorae 8-12 part, Herba mazi japonici 5-8 part, Rubus sieboldi Blume. 5-8 part, Folium Musae 5-8 part, Bulbilus dioscoreae 5-8 part, Herba Gnaphalii Affinis 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Caulis Clematidis Armandii, 18 parts of Semen Ciceris Arietini, 17 parts of Herba Sidae Rhombifoliae, 12 parts of Herba Bulbophylli inconspicui, 10 parts of Radix Beaumontiae Grandiflorae, 8 parts of Herba mazi japonici, 7 parts of Rubus sieboldi Blume., 6 parts of Folium Musae, 5 parts of Bulbilus dioscoreae, 5 parts of Herba Gnaphalii Affinis.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Caulis Clematidis Armandii of selection high-quality, Semen Ciceris Arietini, Herba Sidae Rhombifoliae, Herba Bulbophylli inconspicui, Radix Beaumontiae Grandiflorae, Herba mazi japonici, Rubus sieboldi Blume., Folium Musae, Bulbilus dioscoreae, Herba Gnaphalii Affinis, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets.
Claims (8)
1. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets it is characterised in that：It is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Caulis Clematidis Armandii 50-70 part, Semen Ciceris Arietini 15-20 part, Herba Sidae Rhombifoliae 15-20 part, Herba Bulbophylli inconspicui 8-12 part, Radix Beaumontiae Grandiflorae 8-12 part, Herba mazi japonici 5-8 part, Rubus sieboldi Blume. 5-8 part, Folium Musae 5-8 part, Bulbilus dioscoreae 5-8 part, Herba Gnaphalii Affinis 5-8 part.
2. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Caulis Clematidis Armandii, 18 parts of Semen Ciceris Arietini, 17 parts of Herba Sidae Rhombifoliae, 12 parts of Herba Bulbophylli inconspicui, 10 parts of Radix Beaumontiae Grandiflorae, 8 parts of Herba mazi japonici, 7 parts of Rubus sieboldi Blume., 6 parts of Folium Musae, 5 parts of Bulbilus dioscoreae, 5 parts of Herba Gnaphalii Affinis.
3. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
4. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：Described alkaline agent is sodium carbonate or sodium bicarbonate.
5. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
6. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：Described binding agent is starch slurry or Microcrystalline Cellulose.
7. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1 it is characterised in that：Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
8. a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets according to claim 1-7 and preparation method thereof it is characterised in that：The mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
A, by weight, the Caulis Clematidis Armandii of selection high-quality, Semen Ciceris Arietini, Herba Sidae Rhombifoliae, Herba Bulbophylli inconspicui, Radix Beaumontiae Grandiflorae, Herba mazi japonici, Rubus sieboldi Blume., Folium Musae, Bulbilus dioscoreae, Herba Gnaphalii Affinis, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
B, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
A, the solid particle obtaining in step 1 is divided into uniform two parts, chooses sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
B, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
C, second part of solid particle add the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
D, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets.
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|---|---|---|---|
| CN201510513195.4A CN106466414A (en) | 2015-08-20 | 2015-08-20 | A kind of Caulis Clematidis Armandii clearing away heat and promoting diuresiss bath effervescent tablets and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112022781A (en) * | 2020-09-14 | 2020-12-04 | 甘肃奇正实业集团有限公司 | Multifunctional bath salt ball and preparation method thereof |
-
2015
- 2015-08-20 CN CN201510513195.4A patent/CN106466414A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112022781A (en) * | 2020-09-14 | 2020-12-04 | 甘肃奇正实业集团有限公司 | Multifunctional bath salt ball and preparation method thereof |
| CN112022781B (en) * | 2020-09-14 | 2022-09-02 | 甘肃奇正实业集团有限公司 | Bath salt ball and preparation method thereof |
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