CN103690816B - Eliminate Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast and preparation method thereof - Google Patents
Eliminate Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 8-16 part, Rhizoma Bolbostematis 10-20 part, Fructus Crataegi 10-20 part, Fructus Setariae Germinatus (parched) 5-12 part, Rhizoma Pinelliae 12-22 part, Spina Gleditsiae 25-35 part, Carapax Trionycis 15-30 part, Poria 25-35 part, Bulbus Allii Macrostemonis 25-35 part, Herba asclepiadis curassaevicae 30-40 part, Semen Vaccariae 30-40 part Flos Carthami 30-40 part.It is not smooth that medicinal herb spray of the present invention effectively can alleviate the QI and blood caused by insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, can relaxing muscles and tendons to promote blood circulation, effect of strengthening spleen, tonifying kidney can also be played, having good therapeutical effect to insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, is the medicinal herb spray of the insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast of a kind for the treatment of safe and effective and without any side effects.
Description
Technical field
The invention discloses a kind of Chinese medicine composition, especially a kind ofly eliminate Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast and preparation method thereof.The invention belongs to traditional Chinese medicine field.
Background technology
Nodules of the breast (lump in breast), disease of tcm name, refers to the chronic benign lump that female breast portion is common, with lump in breast and distending pain for primary symptom, is common in young women.Nodules of the breast is found in the disease such as insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, Cystic hyperplasia of breast, mastofibroma of western medicine.Western medicine thinks that cyclomastopathy is relevant with ovarian dysfunction, and as lutein secretion reduces, estrogenic Secretion is to increasing.
Primary disease many with feelings will internal injury, be worried angry relevant.Stomach of foot Yang Ming through breast, liver channel of foot-Jueyin under breast, outside the capable breast of spleen meridian, if feelings will internal injury, angry then liver spleen pent-up of being worried, QI and blood is inverse disorderly, the not all right Tianjin of gas, and body fluid is condensed into expectorant; Multiple because of liver Wood restricts earth, cause spleen and can not transport wet, stomach can not the turbid descending, then the turbid interior life of expectorant; Stagnation of QI expectorant is turbid hinder in newborn network be then lump pain.Eight arteries and veins are subordinate in Liver and kidney, and chong channel is subordinate in sun bright, if pathogenic fire derived from stagnation of liver-QI, and the moon of consume Liver and kidney, then Chong and Ren channel disorder, " Shengji Zonglu " cloud: " rushing wantonly two warps, is above milk, and lower is moon water." so primary disease is how relevant to menstrual cycle.The basic pathogenesis of primary disease is that stagnation of QI expectorant coagulates, and Chong and Ren channel disorder is sick at stomach, liver, spleen three warp.With the lump that breast has shape not of uniform size, pain, cystic hyperplasia of breast class disease for main manifestations relevant to menstrual cycle.
Primary disease is more common in 20 ~ 40 years old women, shows as one-sided or bilateral breast and the single or multiple lump differed in size occurs, distending pain or tenderness, smooth surface, clear border, pushes away movable, increasess slowly, strong but pliable in texture or in cystic sense.Doublely see that lump and distending pain often disappear because of susceptible to anger elder, card belongs to stagnation of QI expectorant and coagulates; If often increase the weight of before menstruation comes, alleviator after menstruation is then Chong and Ren channel disorder.Most have a flat lump at the outside upper quadrant of breast, and that lays one's hand on has the tough hard tubercle of beans size, can have tenderness, and lump border owes clear, with surrounding tissue adhesion.Breast can have distending pain or twinge, the often growth and decline with susceptible to anger, and the moon is premenstrual to be increased the weight of, and alleviates after menstruation.
The Syndrome Types of TCM of nodules of the breast is a lot of, point two types had, point three types had, until four types, five types, six types, seven types etc., very or more.What have is excessively simple, and what have is too numerous.But always nothing more than stagnation of QI due to depression of the liver, stagnation of QI expectorant is solidifying, blood stasis expectorant solidifying, a discord, deficiency of spleen-YANG and kidneyYANG, the hepatic and renal YIN deficiency, QI and blood deficiency etc. are appointed in punching.Though the suggestion of each family is not the same, its pathogenesis all be unable to do without above-mentioned viewpoint.Doctor Li Jimin eliminates nodules of the breast (cyclomastopathy), dialectically is clinically divided into four types to carry out opinion controlling.
1. stagnation of QI due to depression of the liver: stagnation of liver-QI is not relaxed, breast distension, caking distending pain with susceptible to anger growth and decline, time have twinge, two side of body distending pains, bitter taste is irritated, and pale tongue with thin fur is white, stringy pulse or thin string.
2. Chong and Ren channel disorder: breast lumps, dull pain or twinge, localized pain.Premenstrual lump obviously increases, through after reduce deliquescing, or companion's menoxenia, dysmenorrhea, the disease such as infertile.Light red tongue tongue is white, and thready pulse moistens.
3. insufficiency of the spleen expectorant coagulates: lump in breast is comparatively large, but poor growth, the hard distending pain of matter, smooth surface, what push away can move, and clear border, mammary contour is constant.Thin white fur of tongue, stringy and rolling pulse.
4. blood stasis due to renal deficiency: breast caking with the passing of time, twinge or have a dull ache, fix by sore spot.Companion's soreness of waist is weak, and through water is few, color is light, or amenorrhea, the disease such as infertile.There is petechia on the dark or tongue limit of tongue, white and thin fur, deep-thready pulse.
In the method for the insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast of existing elimination, application number is: 200510047163.6 patent discloses a kind ofly treats the Chinese medicine of cystic hyperplasia of breast and mastitis and the preparation method of coated tablet thereof, and it is prepared from by following raw materials in parts by weight number ratio: Cornu Cervi: Herba Taraxaci: Thallus Laminariae (Thallus Eckloniae): Radix Trichosanthis: Caulis Spatholobi: Radix Notoginseng: Radix Paeoniae Rubra: Sargassum: Radix Rhapontici: the Radix Aucklandiae: Radix Scrophulariae: Cortex Moutan: Spica Prunellae: Fructus Forsythiae: Flos Carthami=200-400: 100-300: 600-950: 40-120: 100-300: 100-300: 25-95: 260-480: 80-180: 90-240: 100-300: 180-380: 100-300: 40-120: 80-180.Medicine of the present invention a kind ofly treats cystic hyperplasia of breast and the effective Chinese medicine of mastitis, and it is reducing lump in breast, alleviates the upper Be very effective of carbuncle of breast pain, it rapid-action, and safety is high.Unsatisfactory for the effect eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, extra burden can be caused to the health of patient.
Summary of the invention
For the present situation of existing elimination insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast deficiency, an object of the present invention is to provide a kind of Chinese medicine composition eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, have easy to carry, action effect is obvious, the effect playing blood circulation promoting and blood stasis dispelling that can be very fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Eliminate the Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 8-16 part, Rhizoma Bolbostematis 10-20 part, Fructus Crataegi 10-20 part, Fructus Setariae Germinatus (parched) 5-12 part, Rhizoma Pinelliae 12-22 part, Spina Gleditsiae 25-35 part, Carapax Trionycis 15-30 part, Poria 25-35 part, Bulbus Allii Macrostemonis 25-35 part, Herba asclepiadis curassaevicae 30-40 part, Semen Vaccariae 30-40 part Flos Carthami 30-40 part.
Foregoing Chinese medicine composition, preferred scheme is: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 11-14 part, Rhizoma Bolbostematis 13-18 part, Fructus Crataegi 13-18 part, Fructus Setariae Germinatus (parched) 7-10 part, Rhizoma Pinelliae 16-18 part, Spina Gleditsiae 28-32 part, Carapax Trionycis 20-25 part, Poria 28-32 part, Bulbus Allii Macrostemonis 28-32 part, Herba asclepiadis curassaevicae 33-38 part, Semen Vaccariae 33-38 part Flos Carthami 33-38 part.
Foregoing Chinese medicine composition, the scheme be more preferably is: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Sinensis 13 parts, Rhizoma Bolbostematis 15 parts, Fructus Crataegi 15 parts, Fructus Setariae Germinatus (parched) 9 parts, the Rhizoma Pinelliae 15 parts, Spina Gleditsiae 30 parts, Carapax Trionycis 22 parts, 30 parts, Poria, Bulbus Allii Macrostemonis 30 parts, Herba asclepiadis curassaevicae 35 parts, Semen Vaccariae 35 parts of Flos Carthami 35 parts.
The preparation method of arbitrary described Chinese medicine composition above, preferred scheme is that step is as follows:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 5-15 minute, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 80-120 mesh sieve, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1-2 hour again, standing 20-30 hour, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixes the 0.5-3% that the consumption of medicamental pulverata is filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
Foregoing preparation method, preferred scheme is: step 1. slow fire fries 8-13 minute (preferably 10 minutes).
Foregoing preparation method, preferred scheme is: 2. step crosses 90-110 mesh sieve (preferably 100 mesh sieves).
Foregoing preparation method, preferred scheme is: step 3. filtrate 1 mixes with filtrate 2 and decocts 1.3-1.7 hour (preferably 1.5 hours) again.
Foregoing preparation method, preferred scheme is: 3. step leaves standstill 23-28 hour (preferably 25 hours).
Foregoing preparation method, preferred scheme is, the consumption that 4. step mixes medicamental pulverata is the 1-2% (preferably 1.5%) of filtrate weight.
Present invention also offers the application of described Chinese medicine composition when the medicine of the insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast of preparation treatment, Cystic hyperplasia of breast, mastofibroma.
Both hands and breast warm water are first cleaned up by using method: for making the present invention reach optimum therapeuticing effect, during use, are being sprayed on breast by Chinese medicine composition of the present invention, and with the hands 3 circles are respectively rubbed in left and right, and one for several times, at every turn in right amount, within 7 days, is a course for the treatment of.
This Chinese medicine composition is to the Be very effective eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, not only spleen invigorating, can also blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons to promote blood circulation and QI and blood regulating, improve patient for a long time because of slight illness that insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast brings, and Chinese medicine composition of the present invention is by the direct administration in affected part, can play the effect relieved the pain rapidly.
Eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, the pharmacological effect of each crude drug is respectively:
Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature, return liver; The heart; Spleen channel, effect, enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.
Cure mainly: all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Bolbostematis: bitter, cool.Eliminating stagnation poison, subduing inflammation.Control acute mastitis, scrofula sucutaneous nodule, sore swollen toxin and snakeworm poison.
Fructus Crataegi: acid is sweet, tepor.Help digestion long-pending, dissipating blood stasis blood, expelling tenia.Control meat Ji ， mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia after-pains in puerperal, lochiorrhea, children's's breast food is stagnated.Promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, stomach alkane distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain, hyperlipidemia.
Fructus Setariae Germinatus (parched): Fructus Setariae Germinatus (parched) is a kind of concocting method of Fructus Setariae Germinatus, put in pot and fry to buff and the explosion of large portion with slow fire, taking-up cools.Fructus Setariae Germinatus: sweet is flat.Return spleen, stomach warp.(1) promoting digestion and removing stagnation; Spleen benefiting and stimulating the appetite.Stagnate for food stagnation; Distension is had loose bowels; Insufficiency of the spleen few food; Beriberi edema.(2) help digestion and in, spleen benefiting and stimulating the appetite.Do not disappear for food stagnation, abdominal distention halitosis, weakness of the spleen and stomach, not hungry lack of appetite.Fructus Setariae Germinatus (parched) relatively helps digestion, for not hungry lack of appetite.It is stagnant that Fructus Setariae Germinatus (parched to brown) is apt to eliminate indigestion, do not disappear for stagnant.
The Rhizoma Pinelliae: have another name called: the SANYE Rhizoma Pinelliae; First quarter moon lotus; Three steps are jumped; Ground eight beans; Medicine Canis familiaris L. pellet (Hebei); Keep field; Water is beautiful; Sheep eye; Bai Yang (boundary, Henan, Anhui one band); Fiber crops king fruit; Swallow tail; Ground literary composition.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Control damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness.Outer subduing inflammation., vomiting regurgitation dizzy for abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, interior expectorant, breast gastral cavity painful abdominal mass are vexed, globus hystericus disease; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Spina Gleditsiae: swollen ulcer drug, scrofula, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention, leprosy.
Carapax Trionycis: nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea ， WEIJIA, chronic malaria malaria with splenomegaly.
Bulbus Allii Macrostemonis: acrid in the mouth; Bitter; Warm in nature.Cure mainly: the thorough back of the body of obstruction of qi in the chest and cardialgia; Breast gastral cavity painful abdominal mass is vexed; Cough with asthma abundant expectoration; Epigastric pain; Heavy after letting out dysentery; Leucorrhea; Furuncle carbuncle.
Semen Vaccariae: bitter is flat.Promoting the circulation of blood is stimulated the menstrual flow, and expedites the emergence of stimulating milk secretion, detumescence sore.Control women's amenorrhea, galactostasis, difficult labour, stranguria with blood, carbuncle, incised wound is hemorrhage.
Flos Carthami: irregular menstruation, puerperal abdonimal pain, lump in the abdomen, the diseases such as traumatic stasis swells and ache, ulcer sore pain.
Herba asclepiadis curassaevicae: meridian distribution of property and flavor: bitter, cold.Function cures mainly: anti-inflammatory analgetic, hemostasis.For mastitis, carbuncle furuncle, dysmenorrhea; Fracture is controlled in external, knife injury, eczema, stubborn dermatitis.
Chinese medicine composition of the present invention eliminates the principle of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast based on Chinese medicine.The Chinese medicinal material selected all has blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons to promote blood circulation, effect of regulating the flow of Qi and the middle Jiao, and cheap, and life-time service also can not cause the financial burden of patient, is to eliminate the ideal medicine of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion (getting 10g for every part) and be prepared from: Radix Angelicae Sinensis 8 parts, Rhizoma Bolbostematis 10 parts, Fructus Crataegi 10 parts, Fructus Setariae Germinatus (parched) 5 parts, the Rhizoma Pinelliae 12 parts, Spina Gleditsiae 25 parts, Carapax Trionycis 15 parts, 25 parts, Poria, Bulbus Allii Macrostemonis 25 parts, Herba asclepiadis curassaevicae 30 parts, Semen Vaccariae 30 parts of Flos Carthami 30 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 5 minutes, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 80 mesh sieves, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1 hour again, standing 20 hours, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixing the consumption of medicamental pulverata is 0.5% of filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
typical case onepungent XX, female, 28 years old, Beijing personage, in August, 2011, patient examined, patient's readme when examining: before each menstrual onset 5-7 days, breast distension pain, during menstrual onset, distending pain of the breast is alleviated to some extent, but pain does not disappear, by the time menstruation has not had 5-7 days later pain just can disappear, sometimes feel blue or pressure is excessive time, breast also has the phenomenon of distension pain, sometimes also mood is unhappy, to such an extent as to be unwilling to speak and usually fly into a rage, except above symptom, patient's also myasthenia of limbs often, be unwilling to walk, remove examination in hospital, be diagnosed as: insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, within 10 days after learning Chinese medicine composition of the present invention just before menstrual onset, bring into use.
Alleviate in menstrual onset fore udder pain after using the embodiment of the present invention 1 gained Chinese medicine composition, see that effective continuation again uses 4 courses for the treatment of of embodiment 1 gained Chinese medicine composition, by the time next menstrual onset fore udder pain disappears, patient's self-induction is fully recovered, use again Chinese medicine composition of the present invention to consolidate 2 courses for the treatment of after recovery from illness, drug withdrawal is so far without recurrence.
embodiment 2eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion (getting 20g for every part) and be prepared from: Radix Angelicae Sinensis 16 parts, Rhizoma Bolbostematis 20 parts, Fructus Crataegi 20 parts, Fructus Setariae Germinatus (parched) 12 parts, the Rhizoma Pinelliae 22 parts, Spina Gleditsiae 35 parts, Carapax Trionycis 30 parts, 35 parts, Poria, Bulbus Allii Macrostemonis 35 parts, Herba asclepiadis curassaevicae 40 parts, Semen Vaccariae 40 parts of Flos Carthami 40 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 15 minutes, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 120 mesh sieves, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 2 hours again, standing 30 hours, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixing the consumption of medicamental pulverata is 3% of filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
typical case twolee XX, 26 years old, people from Changsha, the worker of certain factory, in May, 2012 examined, and when examining, patient's readme is near spiritual gloomy over the past half year, susceptible to lose temper due to restlessness.Before four months, accidental sensation bimastism has lump, both sides distending pain of the breast between month paramenstrum, occasionally have sharp, and lump in breast increases with the fluctuation of breast feelings will, spirit is gloomy, sensation of oppression over the chest with shortness of breath, be diagnosed as on inspection " cystic cyclomastopathy ", in outer court's treatment, take " RUPIXIAO, RUHE SANJIE PIAN " and symptom does not subtract and examines.Doctor only listens that patient is oral cannot be confirmed to be what reason causes, inspection through science finds: grow normal, bilateral breast can touch cystic mass as large in egg, soft, movable, the with no pressure pain of matter, color of the leather are constant, with chest without adhesion, nipple secretions without exception; Pale tongue with white fur, thready and stringy pulse.Be diagnosed as: the Cystic hyperplasia of breast that insufficiency of the spleen phlegm-damp causes, due to patient requests's expectant treatment, so doctor advised uses Chinese medicine composition of the present invention.
After using 1 course for the treatment of of the embodiment of the present invention 2 gained Chinese medicine composition, symptom starts to alleviate, face makes moderate progress, the symptom of breast distension and twinge alleviates to some extent, lump diminishes, when using after 4 courses for the treatment of, patient's self-induction symptom disappears substantially, use again Chinese medicine composition of the present invention to consolidate 1 course for the treatment of after recovery from illness, drug withdrawal is so far without recurrence.
embodiment 3eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion (getting 30g for every part) and be prepared from: Radix Angelicae Sinensis 11 parts, Rhizoma Bolbostematis 13 parts, Fructus Crataegi 13 parts, Fructus Setariae Germinatus (parched) 7 parts, the Rhizoma Pinelliae 16 parts, Spina Gleditsiae 28 parts, Carapax Trionycis 20 parts, 28 parts, Poria, Bulbus Allii Macrostemonis 28 parts, Herba asclepiadis curassaevicae 33 parts, Semen Vaccariae 33 parts of Flos Carthami 33 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 8 minutes, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 90 mesh sieves, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1.3 hours again, standing 23 hours, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixing the consumption of medicamental pulverata is 1% of filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
embodiment 4eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion (getting 40g for every part) and be prepared from: Radix Angelicae Sinensis 14 parts, Rhizoma Bolbostematis 18 parts, Fructus Crataegi 18 parts, Fructus Setariae Germinatus (parched) 10 parts, the Rhizoma Pinelliae 18 parts, Spina Gleditsiae 32 parts, Carapax Trionycis 25 parts, 32 parts, Poria, Bulbus Allii Macrostemonis 32 parts, Herba asclepiadis curassaevicae 38 parts, Semen Vaccariae 38 parts of Flos Carthami 38 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 13 minutes, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 110 mesh sieves, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1.7 hours again, standing 28 hours, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixing the consumption of medicamental pulverata is 2% of filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
typical case threelu XX, female, 30 years old, people from Yantai, Shandong, in January, 2013 fell ill, symptom: breast lumps, dull pain or twinge, localized pain.Premenstrual lump obviously increases, through after reduce deliquescing, with menoxenia, dysmenorrhea etc. disease.Doctor watches the complexion jaundice obfuscation of patient, and light red tongue tongue is white, and doctor inquires whether soreness of the waist and knees, the premenstrual soreness of waist of patient's readme is weak, through water is few, color is light, is diagnosed as the Cystic hyperplasia of breast that insufficiency of the spleen phlegm-damp causes, under the suggestion of doctor, brings into use Chinese medicine composition of the present invention through doctor.
After using 2 courses for the treatment of of the embodiment of the present invention 4 resulting composition, malaise symptoms disappears substantially, and patient feels recovery from illness, after using again 2 courses for the treatment of of the present composition after recovery from illness, so far without recurring.
embodiment 5eliminate a Chinese medicine composition for insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, take off the primary raw material stating weight proportion (getting 50g for every part) and be prepared from: Radix Angelicae Sinensis 13 parts, Rhizoma Bolbostematis 15 parts, Fructus Crataegi 15 parts, Fructus Setariae Germinatus (parched) 9 parts, the Rhizoma Pinelliae 15 parts, Spina Gleditsiae 30 parts, Carapax Trionycis 22 parts, 30 parts, Poria, Bulbus Allii Macrostemonis 30 parts, Herba asclepiadis curassaevicae 35 parts, Semen Vaccariae 35 parts of Flos Carthami 35 parts.
The preparation method of above-mentioned Chinese medicine composition, step is:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 10 minutes, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 100 mesh sieves, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1.5 hours again, standing 25 hours, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixing the consumption of medicamental pulverata is 2% of filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
experimental examplein order to verify whether this Chinese medicine composition (embodiment 5) has curative effect to the insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast of elimination, " new Chinese medicine guideline of clinical investigations " according to Ministry of Public Health formulation in 1993 is diagnosis basis, totally 200 routine insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast patients, the mean age is 30 years old.Random division is administration group and matched group.Before the experiments one day, record patient health, look over patient body symptom every day, guarantee administration group and matched group situation basically identical.Administration group uses this product embodiments 5 gained Chinese medicine composition every day, during use, first both hands and breast warm water is cleaned up, be sprayed on breast by Chinese medicine composition of the present invention, with the hands 3 circles are respectively rubbed, 3 times on the one in left and right, each spray 2 grams 7 days is a course for the treatment of.Experimental group is taken or is used other medicines eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast (medicine eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast as RUPIXIAO capsule, nodules of the breast relieving capsule and nodules of the breast cream etc. are conventional) and checks patient body situation every day, makes a record.Criterion, cures: malaise symptoms disappears, effectively: malaise symptoms disappears substantially, invalid: malaise symptoms is unchanged.Result is as following table 1:
Table 1:
efficacy analysis:when administration group (Chinese medicine composition of the present invention) uses 7 days, most patient sensory symptoms obviously alleviates, and obviously feels to take a favorable turn in affected part, and patient's emotion takes a turn for the better, and during medication 14 days, patient is almost recovered, and drug withdrawal a period of time has no repeatedly, and the state of an illness is better controlled.Matched group take medicine after curative effect obvious, but after drug withdrawal, the patient of 94% is recurred again.
Prove through clinical trial, Chinese medicine composition of the present invention is on the insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast of elimination, effective percentage is 98%, cure rate is 95%, 18% is exceeded than the oral medicine effective percentage that other eliminate insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, cure rate exceeds 25%, and thoroughly can remove old complaint, makes the recovery from illness that patient is real; And any burden can not be caused to the health of patient.Chinese medicine composition instant effect of the present invention, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of Chinese medicine composition eliminating insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast safely and effectively.
Claims (6)
1. eliminate the preparation method of the Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast, it is characterized in that: take off the crude drug stating weight proportion: Radix Angelicae Sinensis 13 parts, Rhizoma Bolbostematis 15 parts, Fructus Crataegi 15 parts, Fructus Setariae Germinatus (parched) 9 parts, the Rhizoma Pinelliae 15 parts, Spina Gleditsiae 30 parts, Carapax Trionycis 22 parts, 30 parts, Poria, Bulbus Allii Macrostemonis 30 parts, Herba asclepiadis curassaevicae 35 parts, Semen Vaccariae 35 parts of Flos Carthami 35 parts; Step is as follows:
1. Rhizoma Bolbostematis, Fructus Crataegi, Spina Gleditsiae and Carapax Trionycis slow fire being fried 8-13 minute, frying to drying in the air after giving out fragrance cool, take out dry stand-by;
2. by step 1. gains and Radix Angelicae Sinensis, Fructus Setariae Germinatus (parched), the Rhizoma Pinelliae, Flos Carthami, Bulbus Allii Macrostemonis altogether pulverization cross 90-110 mesh sieve, must medicamental pulverata be mixed for subsequent use;
3. Poria, Herba asclepiadis curassaevicae and Semen Vaccariae are decocted with water 2 times, first time decocts 2 hours, filter, obtain filtrate 1, the filtering residue after filtration is added water and carries out second time decoction, decoct 1.5 hours, filtrate 2, filtrate 1 is mixed with filtrate 2 and decocts 1.3-1.7 hour again, standing 23-28 hour, again filter, obtain filtrate for subsequent use;
4. by step 2. in gained mixing medicamental pulverata pour into step 3. in gained filtrate in, mix homogeneously, mixes the 1-2% that the consumption of medicamental pulverata is filtrate weight, is aided with pharmaceutically acceptable carrier package and obtains.
2. preparation method according to claim 1, is characterized in that: step 1. slow fire fries 10 minutes.
3. preparation method according to claim 1, is characterized in that: 2. step crosses 100 mesh sieves.
4. preparation method according to claim 1, is characterized in that: step 3. filtrate 1 mixes with filtrate 2 and decocts 1.5 hours again.
5. preparation method according to claim 1, is characterized in that: 3. step leaves standstill 25 hours.
6. according to the preparation method described in claim 1, it is characterized in that, the consumption that 4. step mixes medicamental pulverata is 1.5% of filtrate weight.
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