CN106466399A - A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof - Google Patents
A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof Download PDFInfo
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- CN106466399A CN106466399A CN201510513422.3A CN201510513422A CN106466399A CN 106466399 A CN106466399 A CN 106466399A CN 201510513422 A CN201510513422 A CN 201510513422A CN 106466399 A CN106466399 A CN 106466399A
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Abstract
A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, are made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Carnis Anodonta seu crislaria 50-70 part, Rhizoma Dioscoreae Alatae 15-20 part, Herba Clematidis Buchananianae 15-20 part, Mass Galla chinesis et camelliae Fermentata 8-12 part, Herba youngiae japonicae 8-12 part, Radix Ginkgo 5-8 part, Succus Musae 5-8 part, Endocarpium Citri tangerinae 5-8 part, Radix Cayratiae Corniculatae 5-8 part, Ganoderma 5-8 part, the mainly comprising the following steps of preparation method：Step 1, prepare Chinese medicine extract：Clean, remove impurity, mixing, extraction；Step 2, mixing：Prepare acid particles, prepare alkali grain, mixing, tabletting.A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets of the present invention, life-time service has functions that heat clearing away, improving eyesight, removing toxic substances.
Description
Technical field
The present invention relates to a kind of health body-wash articles for use, particularly a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof.
Background technology
In the traditional Chinese medical science, dipping method is one of external treatment, that is, use medicinal liquid or a kind of method containing medicinal liquid water washing bath whole body or local, and its form is varied：Have full bath and claim " liquid medicine bath "；The title again having " scalding ", " fumigation and wash method ", " demibain ", " foot bath " etc. of local bathing, especially scalds the most commonly used.
Chinese dipping, have existed since ancient times.Earliest hospital of China<52 Bingfang>In just have the dipping side controlling baby's epilepsy.《Book of Rites》In say " head has skin ulcer then to wash one's hair, and body has infectionss then to bathe ",《Huang di's Canon of Medicine》In have the record of " its be subject to exopathogen person, bathing the body with hot decoction to induce diaphoresis ", can say, the history of dipping is of long standing and well established, be laid a foundation in the Qin Dynasty, be developed in Chinese Tang, enrich in Song Ming, ripe in the Qing Dynasty.
The common dipping species in current market is broadly divided into three classes, including：Full bath, demibain, foot bath, using method is also very simply it is only necessary in the liquid medicine having dissolved to the bidet entering to mix up water temperature and the water yield or bath bucket, then steep body in water；Client progressively can experience the change of body generation during bathing.
The dipping mechanism of action in general, be medicine act on whole body flesh table, locally, affected part, and through absorb, circulation meridians blood vessels, inside reach internal organs, from outward appearance to inner essence, thus produce effect.Dipping bathing, can play dredging the meridian, activating blood circulation to dissipate blood stasis, wind dispelling cold expelling, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, regulating YIN and YANG, coordinate internal organs, current QI and blood, moisten the health maintenance effect such as foster whole body.Modern pharmacology also confirms that, can improve the content of some immunoglobulins in blood after dipping, strengthens elasticity and the vigor of skin.
Medicine used by dipping on market mostly is medicinal liquid or medicated powder, medicinal liquid or medicated powder is not portable, and composition easily runs off, and medicinal liquid that most of Chinese herbal medicine process or medicated powder cannot the sufficiently effective effective ingredient playing Chinese crude drug, loss or the waste of drug effect can be caused, and be prepared into effervescent tablet and be then easy to preserve and carry, dissolution velocity is fast, bioavailability is high, can improve clinical efficacy.
At present, the medicine of heat clearing away or health product have much on market, but the effect of most drug is not very well, and the side effect of most drug is more, and health can be damaged, and therefore, market is badly in need of a kind of
Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof.
Content of the invention
It is an object of the invention to provide a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, life-time service has heat clearing away, improving eyesight, the effect of removing toxic substances.
The purpose of the present invention is achieved through the following technical solutions：
A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, are made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Carnis Anodonta seu crislaria 50-70 part, Rhizoma Dioscoreae Alatae 15-20 part, Herba Clematidis Buchananianae 15-20 part, Mass Galla chinesis et camelliae Fermentata 8-12 part, Herba youngiae japonicae 8-12 part, Radix Ginkgo 5-8 part, Succus Musae 5-8 part, Endocarpium Citri tangerinae 5-8 part, Radix Cayratiae Corniculatae 5-8 part, Ganoderma 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Carnis Anodonta seu crislaria, 18 parts of Rhizoma Dioscoreae Alatae, 17 parts of Herba Clematidis Buchananianae, 12 parts of Mass Galla chinesis et camelliae Fermentata, 10 parts of Herba youngiae japonicae, 8 parts of Radix Ginkgo, 7 parts of Succus Musae, 6 parts of Endocarpium Citri tangerinae, 5 parts of Radix Cayratiae Corniculatae, 5 parts of Ganoderma.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Carnis Anodonta seu crislaria of selection high-quality, Rhizoma Dioscoreae Alatae, Herba Clematidis Buchananianae, Mass Galla chinesis et camelliae Fermentata, Herba youngiae japonicae, Radix Ginkgo, Succus Musae, Endocarpium Citri tangerinae, Radix Cayratiae Corniculatae, Ganoderma, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets.
In medicine：Carnis Anodonta seu crislaria heat clearing away；YIN nourishing；Improving eyesight；Removing toxic substances；Main dysphoria with smothery sensation；Quench one's thirst；Metrorrhagia；Leukorrhagia；Hemorrhoid complicated by anal fistula；Conjunctival congestion；Rhizoma Dioscoreae Alatae invigorating the spleen to arrest diarrhea；Lung benefiting nourishing kidney；Removing toxic substances sore；Main diarrhea due to hypofunction of the spleen；Emission due to deficiency of the kidney；Leukorrhagia；Frequent micturition；Cough due to consumptive disease；Quench one's thirst；Skin infection festers；Burn；Herba Clematidis Buchananianae antiinflammatory, diuresis, pain relieving；Cure mainly tonsillitiss, pharyngolaryngitis, urethritiss, cystitis, traumatic injury；Mass Galla chinesis et camelliae Fermentata moistening the lung and resolving phlegm, promoting the production of body fluid to quench thirst；Control chronic cough abundant expectoration, pharyngalgia, have blood in stool, proctoptosis with chronic dysentery, aphtha, ulcerative gingivitis, carbuncle swells sore；Herba youngiae japonicae heat-clearing and toxic substances removing, inducing diuresis to remove edema, pain relieving；For pharyngitis, mastitis, toothache, dysuria, cirrhotic ascites；Sore furuncle poison is controlled in external；Radix Ginkgo QI invigorating qi-restoratives；Main seminal emission；The enuresis；Night many, the leucorrhea of frequency, stranguria caused by urinary stone；Succus Musae heat clearing away, quenches the thirst, removing toxic substances；Control pyreticosis polydipsia, infantile convulsion, epilepsy, hypertension complicated headache, furuncle carbuncle, burn；Endocarpium Citri tangerinae stomach dampness elimination；Main turbid damp internal resistance；Feeling of oppression and fullness in the chest and epigastrium；Inappetence；Radix Cayratiae Corniculatae nourishing the lung to arrest cough；Hemostasis；Main pulmonary tuberculosis cough；Sputum mixed with blood；Metrorrhagia；Ganoderma strengthening by means of tonics；For brain-strengthening, antiinflammatory, diuresis, kidney tonifying
.
Beneficial effects of the present invention：One kind of the present invention
Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets, to dysphoria with smothery sensation, quench one's thirst
Main
Disease
Card serves to varying degrees
Heat clearing away, improving eyesight, removing toxic substances
Effect,
There are health care, instant effect, pure natural, no side effectses.
The present invention uses the present invention through two groups of clinical verifications, one of which for treatment group, uses the present invention once daily, is within 7 days a course for the treatment of, and another group of matched group is taken
Capsule for clearing away heat
, once a day, it is within 7 days a course for the treatment of, every group selection outpatient 110, wherein man 55, female 55, max age 75 years old, minimal ages 28 years old, clinical manifestation is dysphoria with smothery sensation, quenches one's thirst, metrorrhagia, leukorrhagia, hemorrhoid complicated by anal fistula, conjunctival congestion
, table one is the contrasting data after taking a course for the treatment of：
Table 1 is taken two groups of courses for the treatment of of before and after and is compared (unit:People)
There were significant differences for treatment group and matched group, it will thus be seen that present invention application clinically has significant curative effect.
Specific embodiment
Embodiment 1
A kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, are made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Carnis Anodonta seu crislaria 50-70 part, Rhizoma Dioscoreae Alatae 15-20 part, Herba Clematidis Buchananianae 15-20 part, Mass Galla chinesis et camelliae Fermentata 8-12 part, Herba youngiae japonicae 8-12 part, Radix Ginkgo 5-8 part, Succus Musae 5-8 part, Endocarpium Citri tangerinae 5-8 part, Radix Cayratiae Corniculatae 5-8 part, Ganoderma 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Carnis Anodonta seu crislaria, 18 parts of Rhizoma Dioscoreae Alatae, 17 parts of Herba Clematidis Buchananianae, 12 parts of Mass Galla chinesis et camelliae Fermentata, 10 parts of Herba youngiae japonicae, 8 parts of Radix Ginkgo, 7 parts of Succus Musae, 6 parts of Endocarpium Citri tangerinae, 5 parts of Radix Cayratiae Corniculatae, 5 parts of Ganoderma.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Carnis Anodonta seu crislaria of selection high-quality, Rhizoma Dioscoreae Alatae, Herba Clematidis Buchananianae, Mass Galla chinesis et camelliae Fermentata, Herba youngiae japonicae, Radix Ginkgo, Succus Musae, Endocarpium Citri tangerinae, Radix Cayratiae Corniculatae, Ganoderma, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets.
Claims (8)
1. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets it is characterised in that：It is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Carnis Anodonta seu crislaria 50-70 part, Rhizoma Dioscoreae Alatae 15-20 part, Herba Clematidis Buchananianae 15-20 part, Mass Galla chinesis et camelliae Fermentata 8-12 part, Herba youngiae japonicae 8-12 part, Radix Ginkgo 5-8 part, Succus Musae 5-8 part, Endocarpium Citri tangerinae 5-8 part, Radix Cayratiae Corniculatae 5-8 part, Ganoderma 5-8 part.
2. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Carnis Anodonta seu crislaria, 18 parts of Rhizoma Dioscoreae Alatae, 17 parts of Herba Clematidis Buchananianae, 12 parts of Mass Galla chinesis et camelliae Fermentata, 10 parts of Herba youngiae japonicae, 8 parts of Radix Ginkgo, 7 parts of Succus Musae, 6 parts of Endocarpium Citri tangerinae, 5 parts of Radix Cayratiae Corniculatae, 5 parts of Ganoderma.
3. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
4. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described alkaline agent is sodium carbonate or sodium bicarbonate.
5. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
6. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described binding agent is starch slurry or Microcrystalline Cellulose.
7. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
8. a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets according to claim 1-7 and preparation method thereof it is characterised in that：The mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
A, by weight, the Carnis Anodonta seu crislaria of selection high-quality, Rhizoma Dioscoreae Alatae, Herba Clematidis Buchananianae, Mass Galla chinesis et camelliae Fermentata, Herba youngiae japonicae, Radix Ginkgo, Succus Musae, Endocarpium Citri tangerinae, Radix Cayratiae Corniculatae, Ganoderma, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
B, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
A, the solid particle obtaining in step 1 is divided into uniform two parts, chooses sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
B, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
C, second part of solid particle add the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
D, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Carnis Anodonta seu crislaria heat clearing away bath effervescent tablets.
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|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107027925A (en) * | 2017-03-27 | 2017-08-11 | 成都大学 | Ganoderma lucidum Assorted Chinese Herbal Tea and preparation method thereof |
| CN108783175A (en) * | 2018-05-02 | 2018-11-13 | 西华大学 | A kind of beef effervescent tablet and preparation method thereof |
-
2015
- 2015-08-20 CN CN201510513422.3A patent/CN106466399A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107027925A (en) * | 2017-03-27 | 2017-08-11 | 成都大学 | Ganoderma lucidum Assorted Chinese Herbal Tea and preparation method thereof |
| CN108783175A (en) * | 2018-05-02 | 2018-11-13 | 西华大学 | A kind of beef effervescent tablet and preparation method thereof |
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