CN106466439A - A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof - Google Patents
A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof Download PDFInfo
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- CN106466439A CN106466439A CN201510513433.1A CN201510513433A CN106466439A CN 106466439 A CN106466439 A CN 106466439A CN 201510513433 A CN201510513433 A CN 201510513433A CN 106466439 A CN106466439 A CN 106466439A
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Abstract
A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Sinocalamus affinis (Rendle) Mc Clure 50-70 part, Radix Cirsii Japonici 15-20 part, Herba Oenanthes Javanicae 15-20 part, Herba Ceratopteridis Thalictroidiss 8-12 part, Herba Toreniae Glabrae 8-12 part, Semen althaeae roseae 5-8 part, Semen Cappariss 5-8 part, Fructus Phoenicis Dactyliferae 5-8 part, Radix Rhododendri 5-8 part, Forsyihia viridissima Lindl 5-8 part, the mainly comprising the following steps of preparation method：Step 1, prepare Chinese medicine extract：Clean, remove impurity, mixing, extraction；Step 2, mixing：Prepare acid particles, prepare alkali grain, mixing, tabletting.A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets of the present invention, life-time service has functions that heat clearing away, removing toxic substances, hemostasis.
Description
Technical field
The present invention relates to a kind of health body-wash articles for use, particularly a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof.
Background technology
In the traditional Chinese medical science, dipping method is one of external treatment, that is, use medicinal liquid or a kind of method containing medicinal liquid water washing bath whole body or local, and its form is varied：Have full bath and claim " liquid medicine bath "；The title again having " scalding ", " fumigation and wash method ", " demibain ", " foot bath " etc. of local bathing, especially scalds the most commonly used.
Chinese dipping, have existed since ancient times.Earliest hospital of China<52 Bingfang>In just have the dipping side controlling baby's epilepsy.《Book of Rites》In say " head has skin ulcer then to wash one's hair, and body has infectionss then to bathe ",《Huang di's Canon of Medicine》In have the record of " its be subject to exopathogen person, bathing the body with hot decoction to induce diaphoresis ", can say, the history of dipping is of long standing and well established, be laid a foundation in the Qin Dynasty, be developed in Chinese Tang, enrich in Song Ming, ripe in the Qing Dynasty.
The common dipping species in current market is broadly divided into three classes, including：Full bath, demibain, foot bath, using method is also very simply it is only necessary in the liquid medicine having dissolved to the bidet entering to mix up water temperature and the water yield or bath bucket, then steep body in water；Client progressively can experience the change of body generation during bathing.
The dipping mechanism of action in general, be medicine act on whole body flesh table, locally, affected part, and through absorb, circulation meridians blood vessels, inside reach internal organs, from outward appearance to inner essence, thus produce effect.Dipping bathing, can play dredging the meridian, activating blood circulation to dissipate blood stasis, wind dispelling cold expelling, heat-clearing and toxic substances removing, reducing swelling and alleviating pain, regulating YIN and YANG, coordinate internal organs, current QI and blood, moisten the health maintenance effect such as foster whole body.Modern pharmacology also confirms that, can improve the content of some immunoglobulins in blood after dipping, strengthens elasticity and the vigor of skin.
Medicine used by dipping on market mostly is medicinal liquid or medicated powder, medicinal liquid or medicated powder is not portable, and composition easily runs off, and medicinal liquid that most of Chinese herbal medicine process or medicated powder cannot the sufficiently effective effective ingredient playing Chinese crude drug, loss or the waste of drug effect can be caused, and be prepared into effervescent tablet and be then easy to preserve and carry, dissolution velocity is fast, bioavailability is high, can improve clinical efficacy.
At present, the medicine of heat clearing away or health product have much on market, but the effect of most drug is not very well, and the side effect of most drug is more, and health can be damaged, and therefore, market is badly in need of a kind of
Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof.
Content of the invention
It is an object of the invention to provide a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, life-time service has heat clearing away, removing toxic substances, the effect of hemostasis.
The purpose of the present invention is achieved through the following technical solutions：
A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Sinocalamus affinis (Rendle) Mc Clure 50-70 part, Radix Cirsii Japonici 15-20 part, Herba Oenanthes Javanicae 15-20 part, Herba Ceratopteridis Thalictroidiss 8-12 part, Herba Toreniae Glabrae 8-12 part, Semen althaeae roseae 5-8 part, Semen Cappariss 5-8 part, Fructus Phoenicis Dactyliferae 5-8 part, Radix Rhododendri 5-8 part, Forsyihia viridissima Lindl 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Sinocalamus affinis (Rendle) Mc Clure, 18 parts of Radix Cirsii Japonici, 17 parts of Herba Oenanthes Javanicae, 12 parts of Herba Ceratopteridis Thalictroidiss, 10 parts of Herba Toreniae Glabrae, 8 parts of Semen althaeae roseae, 7 parts of Semen Cappariss, 6 parts of Fructus Phoenicis Dactyliferae, 5 parts of Radix Rhododendri, 5 parts of Forsyihia viridissima Lindl.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Sinocalamus affinis (Rendle) Mc Clure of selection high-quality, Radix Cirsii Japonici, Herba Oenanthes Javanicae, Herba Ceratopteridis Thalictroidiss, Herba Toreniae Glabrae, Semen althaeae roseae, Semen Cappariss, Fructus Phoenicis Dactyliferae, Radix Rhododendri, Forsyihia viridissima Lindl, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets.
In medicine：Sinocalamus affinis (Rendle) Mc Clure heat clearing away, removing toxic substances, hemostasis, control and quench one's thirst, urine burning pain, proctoptosis, children's head fever of the body skin ulcer, knife injury；Radix Cirsii Japonici cooling blood for hemostasis, removing blood stasis to reduce swelling, for epistaxis, haematemesis, hematuria, have blood in stool, metrostaxiss, traumatic hemorrhage, carbuncle sore tumefacting virus；Herba Oenanthes Javanicae heat clearing away, diuretic；Control sudden high fever excessive thirst, jaundice, edema, gonorrhea, leukorrhagia, scrofula, mumps；Herba Ceratopteridis Thalictroidiss are invigorated blood circulation, removing toxic substances；Control mass in the abdomen, dysentery, fetal toxicosis, traumatic injury；Herba Toreniae Glabrae clearing away heat-damp and promoting diuresis, removing toxic substances, blood stasis dispelling；Control heat syndrome cough, jaundice, dysentery, furunculosis, traumatic injury；Semen althaeae roseae relieving stranguria by diuresis, laxation；Control edema, gonorrhea, constipation, sore scabies；Semen Cappariss heat clearing away is quenched one's thirst, and hastens parturition；Thirsty for calentura, pharyngolaryngitis, malignant sore swollen drug, difficult labour；Fructus Phoenicis Dactyliferae QI invigorating qi-restoratives；Help digestion expectorant；The main deficiency of vital energy is frail；Accumulation of food in the stomach and intes tine due to indigestion；Bring up phlegm when one coughs；Radix Rhododendri heat clearing away, diuresis, control infantile convulsion, nephritis；Forsyihia viridissima Lindl heat clearing away, removing toxic substances, eliminating stagnation, main cold, fever, conjunctival congestion swells
.
Beneficial effects of the present invention：One kind of the present invention
Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets, to quenching one's thirst, urine burning pain etc.
Main
Disease
Card serves to varying degrees
Heat clearing away, removing toxic substances, hemostasis
Effect,
There are health care, instant effect, pure natural, no side effectses.
The present invention uses the present invention through two groups of clinical verifications, one of which for treatment group, uses the present invention once daily, is within 7 days a course for the treatment of, and another group of matched group is taken
Heat clearing away liver cancer tablet
, daily using once, being within 7 days a course for the treatment of, every group selection outpatient 110, wherein man 55, female 55, max age 75 years old, minimal ages 35 years old, clinical manifestation is to quench one's thirst, urine burning pain, proctoptosis, children's head fever of the body skin ulcer, and knife injury is spitted blood
, table one is the contrasting data after taking a course for the treatment of：
Table 1 is taken two groups of courses for the treatment of of before and after and is compared (unit:People)
There were significant differences for treatment group and matched group, it will thus be seen that present invention application clinically has significant curative effect.
Specific embodiment
Embodiment 1
A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, it is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Sinocalamus affinis (Rendle) Mc Clure 50-70 part, Radix Cirsii Japonici 15-20 part, Herba Oenanthes Javanicae 15-20 part, Herba Ceratopteridis Thalictroidiss 8-12 part, Herba Toreniae Glabrae 8-12 part, Semen althaeae roseae 5-8 part, Semen Cappariss 5-8 part, Fructus Phoenicis Dactyliferae 5-8 part, Radix Rhododendri 5-8 part, Forsyihia viridissima Lindl 5-8 part.
In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Sinocalamus affinis (Rendle) Mc Clure, 18 parts of Radix Cirsii Japonici, 17 parts of Herba Oenanthes Javanicae, 12 parts of Herba Ceratopteridis Thalictroidiss, 10 parts of Herba Toreniae Glabrae, 8 parts of Semen althaeae roseae, 7 parts of Semen Cappariss, 6 parts of Fructus Phoenicis Dactyliferae, 5 parts of Radix Rhododendri, 5 parts of Forsyihia viridissima Lindl.
Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
Described alkaline agent is sodium carbonate or sodium bicarbonate.
Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
Described binding agent is starch slurry or Microcrystalline Cellulose.
Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
Described a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof, the mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
a
, by weight, the Sinocalamus affinis (Rendle) Mc Clure of selection high-quality, Radix Cirsii Japonici, Herba Oenanthes Javanicae, Herba Ceratopteridis Thalictroidiss, Herba Toreniae Glabrae, Semen althaeae roseae, Semen Cappariss, Fructus Phoenicis Dactyliferae, Radix Rhododendri, Forsyihia viridissima Lindl, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
b
, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
a
, the solid particle obtaining in step 1 is divided into uniform two parts, choose sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
b
, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
c
, second part
Solid particle adds the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
d
, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets.
Claims (8)
1. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets it is characterised in that：It is made up by following percentage by weight of raw material, Chinese medicine extract 20-35%, sour agent 10-20%, alkaline agent 10-20%, filler 30-50%, binding agent 1-10%, lubricant 1-10%, aromatic 0.1-1%；Raw materials by weight portion in described Chinese medicine extract, Sinocalamus affinis (Rendle) Mc Clure 50-70 part, Radix Cirsii Japonici 15-20 part, Herba Oenanthes Javanicae 15-20 part, Herba Ceratopteridis Thalictroidiss 8-12 part, Herba Toreniae Glabrae 8-12 part, Semen althaeae roseae 5-8 part, Semen Cappariss 5-8 part, Fructus Phoenicis Dactyliferae 5-8 part, Radix Rhododendri 5-8 part, Forsyihia viridissima Lindl 5-8 part.
2. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：In described Chinese medicine extract, raw material presses optimum weight number, 60 parts of Sinocalamus affinis (Rendle) Mc Clure, 18 parts of Radix Cirsii Japonici, 17 parts of Herba Oenanthes Javanicae, 12 parts of Herba Ceratopteridis Thalictroidiss, 10 parts of Herba Toreniae Glabrae, 8 parts of Semen althaeae roseae, 7 parts of Semen Cappariss, 6 parts of Fructus Phoenicis Dactyliferae, 5 parts of Radix Rhododendri, 5 parts of Forsyihia viridissima Lindl.
3. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described sour agent is citric acid or tartaric acid or citric acid or fumaric acid.
4. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described alkaline agent is sodium carbonate or sodium bicarbonate.
5. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described filler is Microcrystalline Cellulose, sucrose, Lactose, sodium chloride, the calcium sulfate mixing of one or more therein.
6. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described binding agent is starch slurry or Microcrystalline Cellulose.
7. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1 it is characterised in that：Described lubricant is the mixing of one of magnesium stearate, sodium lauryl sulphate or two kinds.
8. a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets according to claim 1-7 and preparation method thereof it is characterised in that：The mainly comprising the following steps of its preparation method：
Step 1, prepare Chinese medicine extract：
A, by weight, the Sinocalamus affinis (Rendle) Mc Clure of selection high-quality, Radix Cirsii Japonici, Herba Oenanthes Javanicae, Herba Ceratopteridis Thalictroidiss, Herba Toreniae Glabrae, Semen althaeae roseae, Semen Cappariss, Fructus Phoenicis Dactyliferae, Radix Rhododendri, Forsyihia viridissima Lindl, clean and remove impurity, mix homogeneously after remove impurity, add water to cook three times, the water small fire adding 12-15 times for the first time decocts 90-120 minute, filters, and extracts filtrate, second plus 10-12 times of water moderate heat decocts 60-90 minute, filter, extract filtrate, the water big fire that third time adds 6-8 times decocts 30-45 minute, filter, extract filtrate, mix three filtrates, obtain mixed extract；
B, mixed extract is concentrated, be dried using spray dryer after concentration, obtain solid mixed extract, pulverized 60-80 mesh sieve, and obtained solid particle；
Step 2, mixing：
A, the solid particle obtaining in step 1 is divided into uniform two parts, chooses sour agent, alkaline agent, filler, binding agent, carry out respectively pulverizing 60 mesh sieves；
B, first part of solid particle add the sour agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain acid particles；
C, second part of solid particle add the alkaline agent after pulverizing, filler, binding agent; it is then placed in trough type mixing machine; open trough type mixing machine to mix 30 minutes, add the PVP K30 ethanol solution that concentration is 1%, soft material processed into trough type mixing machine; add to soft material moderate after; soft material is put in oscillating granulator, makes granule, 60 eye mesh screen on oscillating granulator; dry, obtain alkali grain；
D, by acid particles, alkali grain, lubricant, aromatic mixing, put into tabletting in automatic tableting press after fully mixing, aluminum-plastic packaged, obtain a kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets.
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|---|---|---|---|
| CN201510513433.1A CN106466439A (en) | 2015-08-20 | 2015-08-20 | A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof |
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|---|---|---|---|
| CN201510513433.1A CN106466439A (en) | 2015-08-20 | 2015-08-20 | A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof |
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| CN106466439A true CN106466439A (en) | 2017-03-01 |
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| CN201510513433.1A Pending CN106466439A (en) | 2015-08-20 | 2015-08-20 | A kind of Sinocalamus affinis (Rendle) Mc Clure heat clearing away bath effervescent tablets and preparation method thereof |
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