CN106405132A - Chemiluminescence measuring system - Google Patents
Chemiluminescence measuring system Download PDFInfo
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- CN106405132A CN106405132A CN201610729153.9A CN201610729153A CN106405132A CN 106405132 A CN106405132 A CN 106405132A CN 201610729153 A CN201610729153 A CN 201610729153A CN 106405132 A CN106405132 A CN 106405132A
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- 238000006243 chemical reaction Methods 0.000 claims abstract description 95
- 239000007788 liquid Substances 0.000 claims abstract description 85
- 238000011534 incubation Methods 0.000 claims abstract description 34
- 238000002156 mixing Methods 0.000 claims abstract description 30
- 230000033001 locomotion Effects 0.000 claims abstract description 15
- 238000000034 method Methods 0.000 claims abstract description 12
- 230000008569 process Effects 0.000 claims abstract description 11
- 230000007246 mechanism Effects 0.000 claims description 106
- 239000007924 injection Substances 0.000 claims description 86
- 238000002347 injection Methods 0.000 claims description 86
- 239000012530 fluid Substances 0.000 claims description 53
- 238000001514 detection method Methods 0.000 claims description 28
- 239000000126 substance Substances 0.000 claims description 28
- 230000003068 static effect Effects 0.000 claims description 19
- 238000004140 cleaning Methods 0.000 claims description 15
- 238000012360 testing method Methods 0.000 claims description 11
- 239000011521 glass Substances 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 9
- 230000004888 barrier function Effects 0.000 claims description 7
- 230000000149 penetrating effect Effects 0.000 claims description 7
- 230000005622 photoelectricity Effects 0.000 claims description 7
- 230000004044 response Effects 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 6
- 230000003028 elevating effect Effects 0.000 claims description 6
- 238000009413 insulation Methods 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000001360 synchronised effect Effects 0.000 claims description 3
- 238000013519 translation Methods 0.000 claims description 3
- 239000002699 waste material Substances 0.000 claims description 3
- 239000011324 bead Substances 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 claims description 2
- 230000008450 motivation Effects 0.000 claims 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 abstract 3
- 238000005070 sampling Methods 0.000 abstract 2
- 238000005406 washing Methods 0.000 abstract 2
- 230000006698 induction Effects 0.000 abstract 1
- 230000005540 biological transmission Effects 0.000 description 9
- 239000000376 reactant Substances 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000007422 luminescence assay Methods 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 238000000904 thermoluminescence Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/76—Chemiluminescence; Bioluminescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
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- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Plasma & Fusion (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The invention discloses a chemiluminescence measuring system. The chemiluminiscence measuring system comprises a pedestal, a rotating platform, a liquid sampling device, a washing device, a liquid injecting/uniform mixing device, a incubation device, a reading device, and a cup discarding device; the rotating platform is arranged at the center of the pedestal; the rest devices are arranged on the pedestal around the rotating platform; a cup placing position, a liquid sampling position, a liquid uniform mixing position, an incubation position, a washing position, a reading position, and a cup discarding position of the rotating platform are provided with a first Hall sensor respectively for sensing the position of a reaction cup at each work station; a magnet is driven by a motor to perform circling motion together with a rotating disc; when the rotating disc rotates to a corresponding position, induction of the magnet with a corresponding Hall sensor is realized, the rotating disc is stopped, and corresponding measuring operation is carried out at the position. The functions of the chemiluminescence measuring system are abundant; smooth operation and cooperative working of the parts are realized; the structure is designed to be compact and reasonable; complex measuring process can be completed; and automation degree is high.
Description
Technical field
The present invention relates to a kind of chemical luminescent detecting system.
Background technology
Existing chemical luminescent detecting system is although enable automatic detection, but there are problems, such as detects not
Enough accurately structure is not compact, takes up room big, and it is unreasonable also to there is structure design, easily causes reactant and is contaminated, separately
Outward, existing automation equipment degree is not high enough, therefore, it is necessary to design a kind of more sophisticated chemical luminescent detecting system of function
System.
Content of the invention
The technical problem to be solved is to provide a kind of chemical luminescent detecting system, this chemical luminescent detecting system
Compact conformation, runs smooth it is easy to implement.
The technical solution of invention is as follows：
A kind of chemical luminescent detecting system, including base, rotation platform, liquid taking device, cleaning device, fluid injection/mixing dress
Put, incubating device, reading plotter and lose cup device；
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading
Counting apparatus and lose cup device and be all arranged on base around rotation platform；
Rotation platform：Rotation platform includes support, the motor of rotating disk, arc carrier and driving rotating disk and gear；
Rotating disk is arranged on support, rotating disk is endless member, and the internal ring side of rotating disk is provided with for being adapted to described gear
Double wedge；Gear is arranged in the rotating shaft of motor；
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system；On arc carrier
It is provided with the fixture for accommodating reaction cup；
Arc carrier is provided with the Magnet fixed block with Magnet；First Hall element is fixed with support, first suddenly
Your sensor is concordant with the height of Magnet.
Support is provided with for detecting the reaction cup detection sensor that reaction cup whether there is.
Described Hall element is multiple, being arranged circumferentially on support along rotating disk.
Described support includes support ring and the many support columns for supporting support ring.
Supporting column bottom is provided with firm banking.
Reaction cup rotating mechanism is also called rotation platform, and for driving reaction cup to switch in each module, this platform has
Internal-gear type rotary turnplate mechanism, the arc carrier of placing response cup；
The arc carrier of described placing response cup is fixed on rotating disk, and fixture is used for clamping reaction cup, instrument (i.e. chemistry
Luminescence assays system) run when, manually reaction cup place arc carrier on, clamp reaction cup it is ensured that doing circumference fortune
When dynamic, reaction cup is not rocked；
Described Hall element is used for detecting that reaction cup reaches the position of each station；Described reaction cup detection sensing
Device is used for detecting whether arc carrier has reaction cup.
This rotation platform is being put cup position, taking liquid level, liquid blending position, incubation position, cleaning position, reading position and is being lost cup position respectively
It is provided with Hall element, reaches the position of each station for sensing reaction cup, Magnet follows the work in motor for the rotary turnplate
With under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be at this
Position is detected operation accordingly.
Fluid injection/evenly mixing device：Including the second riser, cam flat pushing mechanism and for for reaction cup fluid injection mechanism for filling liquid；
Cam flat pushing mechanism include the second cam, for driving cam rotation the second actuated by cams motor, pushing block, second
Guide post, second back-moving spring；
Described mechanism for filling liquid includes liquid injection pipe fixed plate and the liquid injection pipe being vertically fixed in liquid injection pipe fixed plate；
Riser is provided with pilot hole, and guide post is inserted in pilot hole；Liquid injection pipe fixed plate and pushing block are separately positioned on and lead
Leading section and rearward end to bar；Back-moving spring is sleeved on guide post；
Second cam is contacted with pushing block；During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe
Travel forward.
The second described guide post is 2, and described pilot hole is 2.Fluid injection/evenly mixing device also includes the testing machine that puts in place
Structure, described to position detecting mechanism include the static inducting part that is arranged on riser and being arranged on push away movable on cup mechanism
Trigger unit.Movable trigger unit and static inducting part are respectively magnetic sheet and the second Hall element, or, described work
Dynamic formula trigger unit and static inducting part are respectively light barrier and photoelectricity to penetrating detection module.
Baffle plate is additionally provided with the second riser, baffle plate is located at the lower section of liquid injection pipe fixed plate, baffle plate is provided with for for fluid injection
The bar shaped guide hole of pipe guided in translation；
Fluid injection/evenly mixing device includes rabbling mechanism, and rabbling mechanism includes rabbling mechanism fixed plate, stirring motor and is used for covering
Live the sleeve of reaction cup.
Described rabbling mechanism is driven by Z axis drive mechanism.
Incubating device：Incubating device includes vertical plate and the incubation block being arranged on vertical plate；The outer wall of incubation block is provided with
Thermal insulation board；It is provided with heater in incubation block；
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
Z axis straight-line motion mechanism is lead screw transmission mechanism, including the 3rd motor, screw mandrel, screw mandrel contiguous block be vertically directed
Bar；
The top of vertical plate and bottom are respectively equipped with upper plate and lower shoe, described top and bottom being vertically directed bar
It is separately fixed on upper plate and lower shoe；Screw mandrel contiguous block is arranged on and is vertically directed on bar, and motor is fixed on upper plate
On；The upper end of screw mandrel connects the 3rd motor, the lower end connection wire rod contiguous block of leading screw；Incubation block is fixed on screw mandrel contiguous block；
During the 3rd motor rotation, incubation block edge is driven to be vertically directed bar elevating movement.It is vertically directed bar and be 2.
Reading plotter：
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly, darkroom and PMT reading module；
Described bearing is provided with the guide rail of vertical direction；Lift drive mechanism includes the 4th motor, drive mechanism and leads
Rail contiguous block (95)；Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, and darkroom is read with PMT
Digital-to-analogue block is connected；Motor drives PMT reading module and darkroom to make elevating movement along guide rail by drive mechanism and guide rail contiguous block；
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly；During detection, treat
The reaction cup of detection is located in darkroom.
Drive mechanism is lead screw transmission mechanism.The 4th described motor is motor.Z-axis transmission machine is provided with bearing
Structure, fluid injection/discharge opeing needle assembly is arranged on bearing by Z-axis transmission mechanism.
Lose cup device：Lose cup device to include the first riser, cam mechanism and push away cup mechanism；
Cam mechanism includes the first cam and the first actuated by cams motor for driving cam rotation；
The described cup mechanism that pushes away includes push pedal, the first guide post, (the first back-moving spring and wedge shape pushing block；
Riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole；Wedge shape pushes away
Block and push pedal are separately positioned on leading section and the rearward end of the first guide post；Back-moving spring is sleeved on the first guide post；
First cam is contacted with push pedal；During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape
When pushing block advances, the fixture of clamping reaction cup can be pushed open so that reaction cup departs from fixture.
The first described guide post is 2, and described pilot hole is 2.
Lose cup device and also include Diu Bei testing agency, described Diu Bei testing agency includes the static sense being arranged on riser
Answer part and be arranged on the movable trigger unit pushing away on cup mechanism；Movable trigger unit and static inducting part are respectively magnetic
Piece and Hall element, or, described movable trigger unit and static inducting part are respectively light barrier and photoelectricity to penetrating
Detection module.
Detection process comprises the following steps：
Step 1：Placing response cup；
The rotating disk of rotation platform is in initial position, i.e. zero-bit (A), and reaction cup is now placed on the fixture on arc
On；
Step 2：Take liquid step；
Turntable rotation makes reaction cup reach and takes liquid level (B), injects liquid into reaction cup by Qu Ye mechanism；Described liquid
Including reagent and sample；Qu Ye mechanism completes to take liquid and fluid injection to be existing mature technology
Step 3：Mix step for the first time；
Turntable rotation makes reaction cup reach and mixes position (C), and the rabbling mechanism of fluid injection/evenly mixing device is to the liquid in reaction cup
Body is stirred；
Step 4：Incubation step
Turntable rotation makes reaction cup reach incubation position (D), by incubating device, the liquid in reaction cup is carried out heating incubating
Educate operation；
Step 5：Cleaning step；
Turntable rotation makes reaction cup reach cleaning position (E), cleans the magnetic bead in reaction cup using wiper mechanism；
Step 6：Mix step second；
Turntable rotation makes reaction cup reach and mixes position, and the rabbling mechanism injection triggering agent A liquid of fluid injection/evenly mixing device is simultaneously
Liquid in reaction cup is stirred；
Step 7：Reading step；
Turntable rotation makes reaction cup reach reading position (F), injection triggering agent B liquid, and reading plotter reads reaction result；
Waste liquid is taken away after reading；
Step 8：Lose a glass step；
Turntable rotation makes reaction cup reach to lose cup position (G), pushes away by reaction cup (to hopper and receive by losing cup device
Collection)；
Complete once to be directed to the determination step of reaction cup medicinal liquid.
After step 8, rotating disk continues to be rotated back to zero-bit, chemical luminescent detecting system reset.
Triggering agent A and triggering agent B is also called trgA and trgB, and its composition is respectively sodium hydroxide and hydrogen peroxide, plays and urges
Change acts on.
PMT is photomultiplier tube, is one of photon technology device staple product, and it is that one kind has high sensitivity
Light-detecting device with ultrafast time response.Can be widely applied to photon counting, atomic weak light detection, chemiluminescence, biology
Light research, the detection of extremely low energy-ray, spectrophotometer, polariscope, colorimeter, illumination meter, aeroscope, scopometer, optical density
In meter, the instrument and equipment such as thermoluminescence amount instrument, radio heat meter, scanning electron microscope, biochemistry analyzer.
Beneficial effect：
The chemical luminescent detecting system of the present invention, rotation platform is arranged on middle part, and other mechanisms set around rotation platform
Put, reasonable structural arrangement；
And, the system is provided with liquid taking device, cleaning device, fluid injection/mixing (stirring) device, reading plotter (mensure
Device) and lose cup device, enable the whole flow process of luminescence assays, only need reaction cup manually as on rotation platform, just
Enable the testing process of complexity, export measurement result, high degree of automation.
The advantage of following division each key submodule is located：
(1) automatically lose cup device, cup mechanism is pushed away using the first cam mechanism and realizes losing cup operation, compact conformation, knot
Structure is ingenious, runs smooth, can be with rotation platform slitless connection, tight fit action.
(2) drive mechanism, testing agency (detection reaction cup whether there is), detent mechanism are integrated by reaction cup rotating mechanism
Become an entirety, compact conformation, position detection is carried out using Hall element cooperation Magnet, there is accurate positioning, adopt
With gear and headgear, by step motor drive, there is operation smoothly advantage.
(3) fluid injection/evenly mixing device adopts cam mechanism to promote mechanism for filling liquid to implement fluid injection, immediately exits from noting after the completion of fluid injection
Liquid level, it is to avoid reactant is contaminated；In a word, mechanism compact conformation, runs smooth, can be with testing equipment slitless connection.
(4) incubating device adopts lead-screw drive mechanism and the guiding mechanism based on upright guide rail, can ensure that incubating device is transported
Row is steady and smooth, and incubation block arranges thermal insulation board, can effectively prevent heat to scatter and disappear, in addition, being provided with multiple holes, energy in incubation block
Sample in multiple reaction cup is carried out with incubation operation, efficiency high simultaneously.
(5) interpretation device (i.e. reading plotter) is in the light using darkroom, ensures the accuracy of reading, using based on stepping
The elevating mechanism of motor, lead screw transmission mechanism and guide rail, can ensure fluid injection/smooth operation of discharge opeing needle assembly, be driven using two sets
Mechanism controls PMT module and fluid injection/discharge opeing needle assembly lifting respectively, can neatly control fluid injection, discharge opeing and detection, therefore, this
Kind of interpretation device has compact conformation, perfect in shape and function, the advantages of reading accuracy is high.
In sum, the chemical luminescent detecting systemic-function of the present invention is enriched, and each several part operation is smooth, can work in coordination with mutually work
Make, structure design is compact and reasonable, the common mensure flow process cooperating, complexity being completed, high degree of automation.
Brief description
Fig. 1 is the overall layout chart of chemical luminescent detecting system；
Fig. 2 is the axonometric chart of chemical luminescent detecting system；
Fig. 3 is luminescence assays flow chart；
Fig. 4 is the general structure schematic diagram (axonometric chart) automatically losing cup device of chemical luminescent detecting system；
Fig. 5 is the enlarged drawing of A1 part in Fig. 1；
Fig. 6 is the general structure schematic diagram (top view) automatically losing cup device of chemical luminescent detecting system.
Fig. 7 is the general structure schematic diagram (axonometric chart) of rotation platform；
Fig. 8 is the general structure schematic diagram (top view) of rotation platform；
Fig. 9 is the general structure schematic diagram (side view) of rotation platform.
Figure 10 is the structural representation (axonometric chart) of incubating device；
Figure 11 is the structural representation (top view) of incubating device；
Figure 12 is reading plotter structural representation.
Label declaration：
46- firm banking, 47- arc carrier vertical columns, 48- rotating disk, 49- support ring, 50- arc carrier, 521-
One Hall element, 531- reaction cup detection sensor, 541- support column, 551- Magnet fixed block, 561- gear, 571- stepping
Motor, 581- motor fixed rack.51- first riser, 52- the first actuated by cams motor, 53- first cam, 54- push pedal, 55-
(the first back-moving spring, 56- wedge shape pushing block, 57- fixture, 58- first guide post, 59- hopper, 60- light barrier, 61- photoelectricity is to penetrating
Detection module.
62- the 3rd motor, 63- upper plate, 64- vertical plate, 65- screw mandrel contiguous block, 66- is vertically directed bar, and 67- goes to the bottom
Plate, 68- screw mandrel, 69- is incubated block, 70- thermal insulation board.
71- second riser, 72- baffle plate, 73- liquid injection pipe fixed plate, 74- liquid injection pipe, 75- magnetic sheet, 76- second hall sensing
Device, 77- second back-moving spring, 78- second cam, 79- the second actuated by cams motor, 80- second guide post, 81- stirring motor,
82- sleeve, 83- rabbling mechanism fixed plate.
89- the 4th motor, 90- motor connection block；91- is in the light column, 92- darkroom, 93-PMT module, 94- guide rail, 95-
Guide rail contiguous block, 105- fluid injection/discharge opeing needle assembly.
A- zero-bit, B- takes liquid level, and C- mixes position, and D- is incubated position, E- cleaning position, F- reading position, and G- loses cup position.
Specific embodiment
Below with reference to the drawings and specific embodiments, the present invention is described in further details：
Embodiment 1：
As Fig. 1-12, a kind of chemical luminescent detecting system, including base, rotation platform, liquid taking device, cleaning device, note
Liquid/evenly mixing device, incubating device, reading plotter and lose cup device；
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading
Counting apparatus and lose cup device and be all arranged on base around rotation platform；
Rotation platform putting cup position, take liquid level, liquid blending position, incubation position, cleaning position, reading position and lose cup position and set respectively
It is equipped with Hall element, reaches the position of each station for sensing reaction cup, Magnet follows the effect in motor for the rotary turnplate
Under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be in this position
Put and detected operation accordingly.
Lose cup device to include the first riser 51, the first cam mechanism and push away cup mechanism；
First cam mechanism includes the first cam 53 and the first actuated by cams motor 52 for driving the first cam rotation；
The described cup mechanism that pushes away includes push pedal 54, the first guide post 58, (the first back-moving spring 55 and wedge shape pushing block 56：
First riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole；Wedge
Shape pushing block and push pedal are separately positioned on leading section and the rearward end of the first guide post；(the first back-moving spring is sleeved on the first guide post
On；
First cam is contacted with push pedal；During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape
When pushing block advances, the fixture 57 of clamping reaction cup can be pushed open so that reaction cup departs from fixture, realize losing cup.
The first described guide post is 2, and described pilot hole is 2.
Automatically lose cup device and also include Diu Bei testing agency, described Diu Bei testing agency includes being arranged on the first riser
Static inducting part and be arranged on the movable trigger unit pushing away on cup mechanism.
Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable
Trigger unit and static inducting part are respectively light barrier 60 and photoelectricity to penetrating detection module 61.
Automatically lose the rotation platform that cup device also includes for installs fixture, described fixture is multiple, is arranged on rotation
On platform.
Lose a glass process：Lose before a glass process starts, lose cup device and be in original state, now wedge shape pushing block is in the first reset bullet
It is in retraction position, the initial position of retraction position position wedge shape pushing block in the presence of spring；
Lose a glass process to comprise the following steps：
Step 1：Alignment procedures：The wedge shape pushing block pushing away cup mechanism is directed at the fixture being clamped with reaction cup；
Step 2：Push away a glass step：Start the first actuated by cams motor, first actuated by cams Motor drive the first cam rotates,
First cam promotes push pedal to advance, and wedge shape pushing block and push pedal link, and wedge shape pushing block is pushed fixture open and reached and pushes away cup position so that reaction cup
Depart from the clamping of fixture, complete to lose cup；
Step 3：Reset process：The rear half-turn that first actuated by cams motor shaft rotates a circle is the first cam return action,
Wedge shape pushing block returns to initial position in the presence of (the first back-moving spring, and the sensing chip being now fixed on pushing block and optocoupler pass
Sensor senses, motor stalls；Lose cup to terminate；Initiate to push away a glass step Deng Wait Order next time；
Detect the position of wedge shape pushing block using Diu Bei testing agency；
When wedge shape pushing block is in initial position, the static inducting part being arranged on the first riser can sense and be arranged on
Push away the movable trigger unit on cup mechanism；
When wedge shape pushing block is in and pushes away glass position, described static inducting part can not sense movable trigger unit.
Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable
Trigger unit and static inducting part are respectively light barrier 60 and photoelectricity to penetrating detection module 61.
Fixture is multiple, is arranged on rotation platform and along rotation platform circumferentially, by controlling rotary flat
The anglec of rotation of platform makes wedge shape pushing block and grip alignment.
The lower section of wedge shape pushing block is additionally provided with hopper 59, for the reaction cup guiding collecting box that will abandon.
Rotation platform includes support, the motor 571 of rotating disk 48, arc carrier 50 and driving rotating disk and gear 561；
Rotating disk is arranged on support, rotating disk is endless member, and the internal ring side of rotating disk is provided with for being adapted to described gear
Double wedge；Gear is arranged in the rotating shaft of motor；
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system；On arc carrier
It is provided with the fixture 57 for accommodating reaction cup；
Arc carrier is provided with the Magnet fixed block 551 with Magnet；First Hall element 521 is fixed with support,
Hall element is concordant with the height of Magnet.
Support is provided with for detecting the reaction cup detection sensor 531 that reaction cup whether there is.
Described Hall element is multiple, being arranged circumferentially on support along rotating disk.
Described support includes support ring and the many support columns 541 for supporting support ring.
Supporting column bottom is provided with firm banking 46.
Reaction cup rotating mechanism is also called rotation platform, and for driving reaction cup to switch in each module, this platform has
Internal-gear type rotary turnplate mechanism, the arc carrier of placing response cup；
The arc carrier of described placing response cup is fixed on rotating disk, and fixture is used for clamping reaction cup, instrument (i.e. chemistry
Luminescence assays system) run when, manually reaction cup place arc carrier on, clamp reaction cup it is ensured that doing circumference fortune
When dynamic, reaction cup is not rocked；
Described Hall element is used for detecting that reaction cup reaches the position of each station；Described reaction cup detection sensing
Device is used for detecting whether arc carrier has reaction cup.
Fluid injection/evenly mixing device (evenly mixing device is also known as agitating device) includes the second riser 71, cam flat pushing mechanism and is used for
Fluid injection/evenly mixing device for reaction cup fluid injection；
Cam flat pushing mechanism include the second cam 78, for driving cam rotation the second actuated by cams motor 79, pushing block,
Second guide post 80, second back-moving spring 77；
Described fluid injection/evenly mixing device includes liquid injection pipe fixed plate 73 and the fluid injection being vertically fixed in liquid injection pipe fixed plate
Pipe 74；
Second riser is provided with pilot hole, and guide post is inserted in pilot hole；Liquid injection pipe fixed plate and pushing block are respectively provided with
Leading section and rearward end in the second guide post；Back-moving spring is sleeved on the second guide post；
Second cam is contacted with pushing block；During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe
Travel forward, when reaching foremost, start fluid injection, after the completion of fluid injection, liquid injection pipe fixed plate and liquid injection pipe return reset.
The second described guide post is 2, and described pilot hole is 2.
Fluid injection/the evenly mixing device of described chemical luminescent detecting system also includes position detecting mechanism, the described inspection that puts in place
Survey mechanism includes the static inducting part being arranged on riser and is arranged on the movable trigger unit pushing away on cup mechanism.
Movable trigger unit and static inducting part are respectively magnetic sheet 75 and the second Hall element 76, or, described
Movable trigger unit and static inducting part be respectively light barrier and photoelectricity to penetrating detection module.
Baffle plate 72 is additionally provided with riser, baffle plate is located at the lower section of liquid injection pipe fixed plate, baffle plate is provided with for for liquid injection pipe
The bar shaped guide hole of guided in translation.
Fluid injection/the evenly mixing device of chemical luminescent detecting system also includes the rabbling mechanism below baffle plate, rabbling mechanism
Including rabbling mechanism fixed plate 83, stirring motor 81 and the sleeve 82 for entangling reaction cup.
Described rabbling mechanism is driven by Z axis drive mechanism.
The reaction cup rear stirrer structure that puts in place moves upwards, and reaction cup is pressed into stirring sleeve under the stop of baffle plate, now needs
Will be to reaction cup fluid injection, the second actuated by cams motor action, drive fluid injection/evenly mixing device to advance, after putting in place, be reaction cup note
Liquid.After the completion of fluid injection, the second actuated by cams motor does not reoperate, and in the presence of back-moving spring, fluid injection/evenly mixing device resets.
After liquid liquid enters to finish, stirring motor starts drive stirring sleeve and carries out high-speed motion, to reach the effect of liquid blending.
Incubating device includes vertical plate 64 and the incubation block 69 being arranged on vertical plate；The outer wall of incubation block is provided with thermal insulation board
70；It is provided with heater in incubation block.
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
Z axis straight-line motion mechanism be lead screw transmission mechanism, include the 3rd motor 62, screw mandrel 68, screw mandrel contiguous block 65 and erect
Straight guide post 66；
The top of vertical plate and bottom are respectively equipped with upper plate 63 and lower shoe 67, and being vertically directed bar is 2 so that being incubated
Block runs more steady.
The top and bottom being vertically directed bar are separately fixed on upper plate and lower shoe；Screw mandrel contiguous block is arranged on vertically
On guide post, the 3rd motor is fixed on upper plate；The upper end of screw mandrel connects motor, and the lower end connection wire rod of leading screw connects
Block；Incubation block is fixed on screw mandrel contiguous block；During the 3rd motor rotation, incubation block edge is driven to be vertically directed bar elevating movement.
When needing the sample in reaction cup is incubated, incubation block liter is got up, after the completion of incubation, block will be incubated
Lower resigning.Incubation block top is provided with multiple holes for accommodating reaction cup.
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly 105, darkroom 92 and PMT reading module
93；
Described bearing is provided with the guide rail 94 of vertical direction；Lift drive mechanism includes the 4th motor 89, drive mechanism
With guide rail contiguous block 95；Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, darkroom and PMT
Reading module is connected；4th motor passes through drive mechanism and guide rail contiguous block drives PMT reading module and darkroom to rise along guide rail
Fall motion；
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly；During detection, treat
The reaction cup of detection is located in darkroom, and the column 91 that is in the light is used for being in the light；
Z-axis transmission mechanism is provided with bearing, fluid injection/discharge opeing needle assembly is arranged on bearing by Z-axis transmission mechanism.
Drive mechanism is lead screw transmission mechanism.
The 4th described motor is motor.Motor connection block 90 is used for and leading screw cooperation.During detection, reaction cup is placed in
In darkroom, PMT module is detected and reading to the liquid in reaction cup.Fluid injection/discharge opeing needle assembly decline after to reaction cup plus
Liquid and discharge opeing operation.PMT module is docked with darkroom, and both are located at sustained height (being located at same level position).
When reactant reaches this system, fluid injection/discharge opeing needle assembly declines the injection substrate toward in reaction cup and produces signal, PMT
Reading module rises to close up again and carries out signal detection and output data, and in the process, light-baffling device (darkroom) is that system provides
Dark room conditions.
Darkroom module is fixed in PMT reading module, and PMT reading module is used for carrying out reading detection, darkroom to reactant
Module completely cuts off the accuracy of the ambient guarantee reading of reactant；Fluid injection/discharge opeing needle assembly includes liquid injection pipe fixed plate, fluid injection
Pipe, discharging tube, influidic pipe fixed block, this assembly is used for producing signal to reactant injection substrate, after discharging tube is used for reading
Reaction cup carries out waste liquid exclusion；Fluid injection realizes accurate liquid feeding by plunger displacement pump, and plunger displacement pump is a kind of energy liquid with precise control sample-adding
The device of amount；This assembly is existing mature modules.
Claims (10)
1. a kind of chemical luminescent detecting system is it is characterised in that include base, rotation platform, liquid taking device, cleaning device, note
Liquid/evenly mixing device, incubating device, reading plotter and lose cup device；
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading dress
Put and lose cup device to be all arranged on base around rotation platform；
Rotation platform includes support, the motor (571) of rotating disk (48), arc carrier (50) and driving rotating disk and gear
(561)；
Rotating disk is arranged on support, and rotating disk is endless member, and the internal ring side of rotating disk is provided with the double wedge for being adapted to described gear；
Gear is arranged in the rotating shaft of motor；
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system；Arc carrier is provided with
For accommodating the fixture (57) of reaction cup；
Arc carrier is provided with the Magnet fixed block (551) with Magnet；First Hall element (521) is fixed with support,
First Hall element is concordant with the height of Magnet；
The first described Hall element is multiple, being arranged circumferentially on support along rotating disk；
The first described Hall element is used for detecting that reaction cup reaches the position of each station；
This rotation platform putting cup position, take liquid level, liquid blending position, incubation position, cleaning position, reading position and lose cup position and be respectively provided with
There is the first Hall element, reach the position of each station for sensing reaction cup, Magnet follows the work in motor for the rotary turnplate
With under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be at this
Position is detected operation accordingly.
2. chemical luminescent detecting system according to claim 1 it is characterised in that：
Including the second riser (71), cam flat pushing mechanism and for for reaction cup fluid injection mechanism for filling liquid；
Cam flat pushing mechanism include the second cam (78), for driving cam rotation the second actuated by cams motor (79), pushing block,
Second guide post (80), second back-moving spring (77)；
Described mechanism for filling liquid includes liquid injection pipe fixed plate (73) and the liquid injection pipe (74) being vertically fixed in liquid injection pipe fixed plate；
Riser is provided with pilot hole, and guide post is inserted in pilot hole；Liquid injection pipe fixed plate and pushing block are separately positioned on guide post
Leading section and rearward end；Back-moving spring is sleeved on guide post；
Second cam is contacted with pushing block；During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe forward
Motion.
3. chemical luminescent detecting system according to claim 2 is it is characterised in that be additionally provided with baffle plate on the second riser
(72), baffle plate is located at the lower section of liquid injection pipe fixed plate, and baffle plate is provided with for the bar shaped guide hole for liquid injection pipe guided in translation；
Fluid injection/evenly mixing device includes rabbling mechanism, and rabbling mechanism includes rabbling mechanism fixed plate (83), stirring motor (81) and uses
In the sleeve (82) entangling reaction cup.
4. chemical luminescent detecting system according to claim 1 it is characterised in that incubating device include vertical plate (64) and
It is arranged on the incubation block (69) on vertical plate；The outer wall of incubation block is provided with thermal insulation board (70)；It is provided with heater in incubation block；
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
5. chemical luminescent detecting system according to claim 4 is it is characterised in that Z axis straight-line motion mechanism passes for screw mandrel
Motivation structure, including the 3rd motor (62), screw mandrel (68), screw mandrel contiguous block (65) be vertically directed bar (66)；
The top of vertical plate and bottom are respectively equipped with upper plate (63) and lower shoe (67), the described upper end being vertically directed bar and
Lower end is separately fixed on upper plate and lower shoe；Screw mandrel contiguous block is arranged on and is vertically directed on bar, and motor is fixed on
On base plate；The upper end of screw mandrel connects the 3rd motor, the lower end connection wire rod contiguous block of leading screw；Incubation block is fixed on screw mandrel contiguous block
On；During the 3rd motor rotation, incubation block edge is driven to be vertically directed bar elevating movement.It is vertically directed bar and be 2.
6. chemical luminescent detecting system according to claim 1 it is characterised in that
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly (105), darkroom (92) and PMT reading module；
Described bearing is provided with the guide rail of vertical direction；Lift drive mechanism includes the 4th motor (89), drive mechanism and leads
Rail contiguous block (95)；Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, and darkroom is read with PMT
Digital-to-analogue block is connected；Motor drives PMT reading module and darkroom to make elevating movement along guide rail by drive mechanism and guide rail contiguous block；
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly；During detection, to be detected
Reaction cup be located at darkroom in.
7. chemical luminescent detecting system according to claim 1 includes the first riser it is characterised in that losing cup device
(51), cam mechanism and push away cup mechanism；
Cam mechanism includes the first cam (53) and the first actuated by cams motor (52) for driving the first cam rotation；
The described cup mechanism that pushes away includes push pedal (54), the first guide post (58), (the first back-moving spring (55) and wedge shape pushing block (56)；
First riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole；Wedge shape pushes away
Block and push pedal are separately positioned on leading section and the rearward end of the first guide post；Back-moving spring is sleeved on the first guide post；
First cam is contacted with push pedal；During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape pushing block
During advance, the fixture (57) of clamping reaction cup can be pushed open so that reaction cup departs from fixture.
8. chemical luminescent detecting system according to claim 7 also includes losing a glass testing machine it is characterised in that losing cup device
Structure, described Diu Bei testing agency include the static inducting part that is arranged on riser and being arranged on push away movable on cup mechanism
Trigger unit；Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable
Trigger unit and static inducting part are respectively light barrier (60) and photoelectricity to penetrating detection module (61).
9. chemical luminescent detecting system according to claim 1 is it is characterised in that detection process comprises the following steps：
Step 1：Placing response cup；
The rotating disk of rotation platform is in initial position, i.e. zero-bit (A), now reaction cup is placed on the fixture on arc；
Step 2：Take liquid step；
Turntable rotation makes reaction cup reach and takes liquid level (B), injects liquid into reaction cup by Qu Ye mechanism；Described liquid includes
Reagent and sample；
Step 3：Mix step for the first time；
Turntable rotation makes reaction cup reach and mixes position (C), and the rabbling mechanism of fluid injection/evenly mixing device enters to the liquid in reaction cup
Row stirring；
Step 4：Incubation step
Turntable rotation makes reaction cup reach incubation position (D), by incubating device, the liquid in reaction cup is carried out with the incubation behaviour that heats
Make；
Step 5：Cleaning step；
Turntable rotation makes reaction cup reach cleaning position (E), cleans the magnetic bead in reaction cup using wiper mechanism；
Step 6：Mix step second；
Turntable rotation makes reaction cup reach and mixes position, and the rabbling mechanism injection of fluid injection/evenly mixing device triggers agent A liquid and to anti-
The liquid in cup is answered to be stirred；
Step 7：Reading step；
Turntable rotation makes reaction cup reach reading position (F), injection triggering agent B liquid, and reading plotter reads reaction result；Reading
After take waste liquid away；
Step 8：Lose a glass step；
Turntable rotation makes reaction cup arrival lose cup position (G), pushes away by reaction cup by losing cup device；
Complete once to be directed to the determination step of reaction cup medicinal liquid.
10. chemical luminescent detecting system according to claim 9 is it is characterised in that after step 8, rotating disk continues rotation
Return to zero-bit, chemical luminescent detecting system reset.
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| CN201610729153.9A CN106405132B (en) | 2016-08-26 | 2016-08-26 | A kind of chemical luminescent detecting system |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106771291A (en) * | 2017-02-17 | 2017-05-31 | 安图实验仪器(郑州)有限公司 | Full-automatic chemiluminescence immunoassay analysis meter dcs |
| CN106771306A (en) * | 2017-02-22 | 2017-05-31 | 长沙开元仪器股份有限公司 | A kind of hollow turn-plate type sample-sending |
| CN107102159A (en) * | 2017-04-27 | 2017-08-29 | 安徽工程大学 | For Multi-example water quality while the self-reacting device and its detection method of on-line checking |
| CN107894375A (en) * | 2017-12-27 | 2018-04-10 | 上海神开石油仪器有限公司 | Full-automatic kinematic viscosity analyzer of working continuously |
| CN108444799A (en) * | 2018-04-28 | 2018-08-24 | 广州市进德生物科技有限公司 | A kind of blending incubation device |
| CN111380284A (en) * | 2020-03-23 | 2020-07-07 | 珠海丽珠试剂股份有限公司 | Reagent refrigerating plant and check out test set |
| WO2021007853A1 (en) * | 2019-07-18 | 2021-01-21 | 烟台艾德康生物科技有限公司 | Fully-automatic magnetic bead cleaning device |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040053414A1 (en) * | 2002-09-17 | 2004-03-18 | Devlin, William Jackson | Increasing throughput of an automatic clinical analyzer system by partitioning assays according to frequency of requested performance |
| CN203232040U (en) * | 2013-05-23 | 2013-10-09 | 博奥赛斯（天津）生物科技有限公司 | Reaction disc |
| US20140273245A1 (en) * | 2013-03-15 | 2014-09-18 | Toshiba Medical Systems Corporation | Automated diagnostic analyzers having vertically arranged carousels and related methods |
| CN205991944U (en) * | 2016-08-26 | 2017-03-01 | 深圳市库贝尔生物科技股份有限公司 | A kind of chemical luminescence detector |
-
2016
- 2016-08-26 CN CN201610729153.9A patent/CN106405132B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040053414A1 (en) * | 2002-09-17 | 2004-03-18 | Devlin, William Jackson | Increasing throughput of an automatic clinical analyzer system by partitioning assays according to frequency of requested performance |
| US20140273245A1 (en) * | 2013-03-15 | 2014-09-18 | Toshiba Medical Systems Corporation | Automated diagnostic analyzers having vertically arranged carousels and related methods |
| CN203232040U (en) * | 2013-05-23 | 2013-10-09 | 博奥赛斯（天津）生物科技有限公司 | Reaction disc |
| CN205991944U (en) * | 2016-08-26 | 2017-03-01 | 深圳市库贝尔生物科技股份有限公司 | A kind of chemical luminescence detector |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106771291A (en) * | 2017-02-17 | 2017-05-31 | 安图实验仪器(郑州)有限公司 | Full-automatic chemiluminescence immunoassay analysis meter dcs |
| CN106771306A (en) * | 2017-02-22 | 2017-05-31 | 长沙开元仪器股份有限公司 | A kind of hollow turn-plate type sample-sending |
| CN107102159A (en) * | 2017-04-27 | 2017-08-29 | 安徽工程大学 | For Multi-example water quality while the self-reacting device and its detection method of on-line checking |
| CN107102159B (en) * | 2017-04-27 | 2018-11-13 | 安徽工程大学 | For Multi-example water quality while the self-reacting device and its detection method of on-line checking |
| CN107894375A (en) * | 2017-12-27 | 2018-04-10 | 上海神开石油仪器有限公司 | Full-automatic kinematic viscosity analyzer of working continuously |
| CN108444799A (en) * | 2018-04-28 | 2018-08-24 | 广州市进德生物科技有限公司 | A kind of blending incubation device |
| CN108444799B (en) * | 2018-04-28 | 2024-05-24 | 广州市进德生物科技有限公司 | Mixing incubation device |
| WO2021007853A1 (en) * | 2019-07-18 | 2021-01-21 | 烟台艾德康生物科技有限公司 | Fully-automatic magnetic bead cleaning device |
| CN111380284A (en) * | 2020-03-23 | 2020-07-07 | 珠海丽珠试剂股份有限公司 | Reagent refrigerating plant and check out test set |
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| CN106405132B (en) | 2018-05-22 |
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