CN205991944U - A kind of chemical luminescence detector - Google Patents

A kind of chemical luminescence detector Download PDF

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Publication number
CN205991944U
CN205991944U CN201620946694.2U CN201620946694U CN205991944U CN 205991944 U CN205991944 U CN 205991944U CN 201620946694 U CN201620946694 U CN 201620946694U CN 205991944 U CN205991944 U CN 205991944U
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cup
cam
block
motor
rotating disk
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苏深广
魏坤原
梁玉玲
肖辉
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Shenzhen Icubio Biotechnology Polytron Technologies Inc
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Shenzhen Icubio Biotechnology Polytron Technologies Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence

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  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

The utility model discloses a kind of chemical luminescence detector, including base, rotation platform, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading plotter with lose cup device;Rotation platform is arranged on the central authorities of base, and remaining device is all arranged on base around rotation platform;This rotation platform putting cup position, take liquid level, liquid blending position, incubation position, cleaning position, reading position and lose cup position and be respectively arranged with the first Hall element, reach the position of each station for sensing reaction cup, Magnet is followed rotary turnplate and is circled in the presence of motor, when turntable rotation is to relevant position, Magnet is sensed with Hall element, rotating disk stops, and will be detected operation accordingly in this position.Chemical luminescence detector feature richness of the present utility model, each several part operation is smooth, can mutually interact, structure design is compact and reasonable, the common mensure flow process cooperating, completing complexity, high degree of automation.

Description

A kind of chemical luminescence detector
Technical field
This utility model is related to a kind of chemical luminescence detector.
Background technology
Existing chemical luminescence detector is although enable automatic detection, but there are problems, such as detects not Accurately, structure is not compact, takes up room big, and it is unreasonable also to there is structure design, easily causes reactant and is contaminated, separately Outward, existing automation equipment degree is not high enough, therefore, it is necessary to design a kind of more sophisticated chemical luminescent detecting of function Instrument.
Utility model content
Technical problem to be solved in the utility model is to provide a kind of chemical luminescence detector, this chemical luminescence detector Compact conformation, runs smooth it is easy to implement.
The technical solution of utility model is as follows:
A kind of chemical luminescence detector, including base, rotation platform, liquid taking device, cleaning device, fluid injection/evenly mixing device, Incubating device, reading plotter and lose cup device;
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading Counting apparatus and lose cup device and be all arranged on base around rotation platform;
Rotation platform:Rotation platform includes support, the motor of rotating disk, arc carrier and driving rotating disk and gear;
Rotating disk is arranged on support, rotating disk is endless member, and the internal ring side of rotating disk is provided with for being adapted to described gear Double wedge;Gear is arranged in the rotating shaft of motor;
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system;On arc carrier It is provided with the fixture for accommodating reaction cup;
Arc carrier is provided with the Magnet fixed block with Magnet;First Hall element is fixed with support, first suddenly Your sensor is concordant with the height of Magnet.
Support is provided with for detecting the reaction cup detection sensor that reaction cup whether there is.
Described Hall element is multiple, being arranged circumferentially on support along rotating disk.
Described support includes support ring and the many support columns for supporting support ring.
Supporting column bottom is provided with firm banking.
Reaction cup rotating mechanism is also called rotation platform, and for driving reaction cup to switch in each module, this platform has Internal-gear type rotary turnplate mechanism, the arc carrier of placing response cup;
The arc carrier of described placing response cup is fixed on rotating disk, and fixture is used for clamping reaction cup, instrument (i.e. chemistry Luminous tester) run when, manually reaction cup place arc carrier on, clamp reaction cup is it is ensured that moving in a circle When reaction cup do not rock;
Described Hall element is used for detecting that reaction cup reaches the position of each station;Described reaction cup detection sensing Device is used for detecting whether arc carrier has reaction cup.
This rotation platform is being put cup position, taking liquid level, liquid blending position, incubation position, cleaning position, reading position and is being lost cup position respectively It is provided with Hall element, reaches the position of each station for sensing reaction cup, Magnet follows the work in motor for the rotary turnplate With under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be at this Position is detected operation accordingly.
Fluid injection/evenly mixing device:Including the second riser, cam flat pushing mechanism and for for reaction cup fluid injection mechanism for filling liquid;
Cam flat pushing mechanism include the second cam, for driving cam rotation the second actuated by cams motor, pushing block, second Guide post, second back-moving spring;
Described mechanism for filling liquid includes liquid injection pipe fixed plate and the liquid injection pipe being vertically fixed in liquid injection pipe fixed plate;
Riser is provided with pilot hole, and guide post is inserted in pilot hole;Liquid injection pipe fixed plate and pushing block are separately positioned on and lead Leading section and rearward end to bar;Back-moving spring is sleeved on guide post;
Second cam is contacted with pushing block;During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe Travel forward.
The second described guide post is 2, and described pilot hole is 2.Fluid injection/evenly mixing device also includes the testing machine that puts in place Structure, described to position detecting mechanism include the static inducting part that is arranged on riser and being arranged on push away movable on cup mechanism Trigger unit.Movable trigger unit and static inducting part are respectively magnetic sheet and the second Hall element, or, described work Dynamic formula trigger unit and static inducting part are respectively light barrier and photoelectricity to penetrating detection module.
Baffle plate is additionally provided with the second riser, baffle plate is located at the lower section of liquid injection pipe fixed plate, baffle plate is provided with for for fluid injection The bar shaped guide hole of pipe guided in translation;
Fluid injection/evenly mixing device includes rabbling mechanism, and rabbling mechanism includes rabbling mechanism fixed plate, stirring motor and is used for covering Live the sleeve of reaction cup.
Described rabbling mechanism is driven by Z axis drive mechanism.
Incubating device:Incubating device includes vertical plate and the incubation block being arranged on vertical plate;The outer wall of incubation block is provided with Thermal insulation board;It is provided with heater in incubation block;
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
Z axis straight-line motion mechanism is lead screw transmission mechanism, including the 3rd motor, screw mandrel, screw mandrel contiguous block be vertically directed Bar;
The top of vertical plate and bottom are respectively equipped with upper plate and lower shoe, described top and bottom being vertically directed bar It is separately fixed on upper plate and lower shoe;Screw mandrel contiguous block is arranged on and is vertically directed on bar, and motor is fixed on upper plate On;The upper end of screw mandrel connects the 3rd motor, the lower end connection wire rod contiguous block of leading screw;Incubation block is fixed on screw mandrel contiguous block; During the 3rd motor rotation, incubation block edge is driven to be vertically directed bar elevating movement.It is vertically directed bar and be 2.
Reading plotter:
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly, darkroom and PMT reading module;
Described bearing is provided with the guide rail of vertical direction;Lift drive mechanism includes the 4th motor, drive mechanism and leads Rail contiguous block (95);Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, and darkroom is read with PMT Digital-to-analogue block is connected;Motor drives PMT reading module and darkroom to make elevating movement along guide rail by drive mechanism and guide rail contiguous block; Photomultiplier tube (PMT) is one of photon technology device staple product, it be one kind have high sensitivity and ultrafast when Between response light-detecting device.Can be widely applied to photon counting, atomic weak light detection, chemiluminescence, bioluminescence research, pole Low energy rays detection, spectrophotometer, polariscope, colorimeter, illumination meter, aeroscope, scopometer, photodensitometer, thermoluminescence In the instrument and equipments such as amount instrument, radio heat meter, scanning electron microscope, biochemistry analyzer.
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly;During detection, treat The reaction cup of detection is located in darkroom.
Drive mechanism is lead screw transmission mechanism.The 4th described motor is motor.Z-axis transmission machine is provided with bearing Structure, fluid injection/discharge opeing needle assembly is arranged on bearing by Z-axis transmission mechanism.
Lose cup device:Lose cup device to include the first riser, cam mechanism and push away cup mechanism;
Cam mechanism includes the first cam and the first actuated by cams motor for driving cam rotation;
The described cup mechanism that pushes away includes push pedal, the first guide post, (the first back-moving spring and wedge shape pushing block;
Riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole;Wedge shape pushes away Block and push pedal are separately positioned on leading section and the rearward end of the first guide post;Back-moving spring is sleeved on the first guide post;
First cam is contacted with push pedal;During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape When pushing block advances, the fixture of clamping reaction cup can be pushed open so that reaction cup departs from fixture.
The first described guide post is 2, and described pilot hole is 2.
Lose cup device and also include Diu Bei testing agency, described Diu Bei testing agency includes the static sense being arranged on riser Answer part and be arranged on the movable trigger unit pushing away on cup mechanism;Movable trigger unit and static inducting part are respectively magnetic Piece and Hall element, or, described movable trigger unit and static inducting part are respectively light barrier and photoelectricity to penetrating Detection module.
Triggering agent A and triggering agent B is also called trgA and trgB, and its composition is respectively sodium hydroxide and hydrogen peroxide, plays and urges Change acts on.
Beneficial effect:
Chemical luminescence detector of the present utility model, rotation platform is arranged on middle part, other mechanisms are around rotation platform Setting, reasonable structural arrangement;
And, the system is provided with liquid taking device, cleaning device, fluid injection/mixing (stirring) device, reading plotter (mensure Device) and lose cup device, enable the whole flow process of luminescence assays, only need reaction cup manually as on rotation platform, just Enable the testing process of complexity, export measurement result, high degree of automation.
The advantage of following division each key submodule is located:
(1) automatically lose cup device, cup mechanism is pushed away using the first cam mechanism and realizes losing cup operation, compact conformation, knot Structure is ingenious, runs smooth, can be with rotation platform slitless connection, tight fit action.
(2) drive mechanism, testing agency (detection reaction cup whether there is), detent mechanism are integrated by reaction cup rotating mechanism Become an entirety, compact conformation, position detection is carried out using Hall element cooperation Magnet, there is accurate positioning, adopt With gear and headgear, by step motor drive, there is operation smoothly advantage.
(3) fluid injection/evenly mixing device adopts cam mechanism to promote mechanism for filling liquid to implement fluid injection, immediately exits from noting after the completion of fluid injection Liquid level, it is to avoid reactant is contaminated;In a word, mechanism compact conformation, runs smooth, can be with testing equipment slitless connection.
(4) incubating device adopts lead-screw drive mechanism and the guiding mechanism based on upright guide rail, can ensure that incubating device is transported Row is steady and smooth, and incubation block arranges thermal insulation board, can effectively prevent heat to scatter and disappear, in addition, being provided with multiple holes, energy in incubation block Sample in multiple reaction cup is carried out with incubation operation, efficiency high simultaneously.
(5) interpretation device (i.e. reading plotter) is in the light using darkroom, ensures the accuracy of reading, using based on stepping The elevating mechanism of motor, lead screw transmission mechanism and guide rail, can ensure fluid injection/smooth operation of discharge opeing needle assembly, be driven using two sets Mechanism controls PMT module and fluid injection/discharge opeing needle assembly lifting respectively, can neatly control fluid injection, discharge opeing and detection, therefore, this Kind of interpretation device has compact conformation, perfect in shape and function, the advantages of reading accuracy is high.
In sum, chemical luminescence detector feature richness of the present utility model, each several part operation is smooth, can work in coordination with mutually Work, structure design is compact and reasonable, the common mensure flow process cooperating, completing complexity, high degree of automation.
Brief description
Fig. 1 is the overall layout chart of chemical luminescence detector;
Fig. 2 is the axonometric chart of chemical luminescence detector;
Fig. 3 is luminescence assays flow chart;
Fig. 4 is the structural representation (axonometric chart) automatically losing cup device of chemical luminescence detector;
Fig. 5 is the enlarged drawing of A1 part in Fig. 1;
Fig. 6 is the general structure schematic diagram (top view) automatically losing cup device of chemical luminescence detector.
Fig. 7 is the general structure schematic diagram (axonometric chart) of rotation platform;
Fig. 8 is the general structure schematic diagram (top view) of rotation platform;
Fig. 9 is the general structure schematic diagram (side view) of rotation platform.
Figure 10 is the structural representation (axonometric chart) of incubating device;
Figure 11 is the structural representation (top view) of incubating device;
Figure 12 is reading plotter structural representation.
Label declaration:
46- firm banking, 47- arc carrier vertical columns, 48- rotating disk, 49- support ring, 50- arc carrier, 521- One Hall element, 531- reaction cup detection sensor, 541- support column, 551- Magnet fixed block, 561- gear, 571- stepping Motor, 581- motor fixed rack.51- first riser, 52- the first actuated by cams motor, 53- first cam, 54- push pedal, 55- (the first back-moving spring, 56- wedge shape pushing block, 57- fixture, 58- first guide post, 59- hopper, 60- light barrier, 61- photoelectricity is to penetrating Detection module.
62- the 3rd motor, 63- upper plate, 64- vertical plate, 65- screw mandrel contiguous block, 66- is vertically directed bar, and 67- goes to the bottom Plate, 68- screw mandrel, 69- is incubated block, 70- thermal insulation board.
71- second riser, 72- baffle plate, 73- liquid injection pipe fixed plate, 74- liquid injection pipe, 75- magnetic sheet, 76- second hall sensing Device, 77- second back-moving spring, 78- second cam, 79- the second actuated by cams motor, 80- second guide post, 81- stirring motor, 82- sleeve, 83- rabbling mechanism fixed plate.
89- the 4th motor, 90- motor connection block;91- is in the light column, 92- darkroom, 93-PMT module, 94- guide rail, 95- Guide rail contiguous block, 105- fluid injection/discharge opeing needle assembly.
A- zero-bit, B- takes liquid level, and C- mixes position, and D- is incubated position, E- cleaning position, F- reading position, and G- loses cup position.
Specific embodiment
Below with reference to the drawings and specific embodiments, this utility model is described in further details:
Embodiment 1:
As Fig. 1-12, a kind of chemical luminescence detector, including base, rotation platform, liquid taking device, cleaning device, fluid injection/ Evenly mixing device, incubating device, reading plotter and lose cup device;
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading Counting apparatus and lose cup device and be all arranged on base around rotation platform;
Rotation platform putting cup position, take liquid level, liquid blending position, incubation position, cleaning position, reading position and lose cup position and set respectively It is equipped with Hall element, reaches the position of each station for sensing reaction cup, Magnet follows the effect in motor for the rotary turnplate Under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be in this position Put and detected operation accordingly.
Lose cup device to include the first riser 51, the first cam mechanism and push away cup mechanism;
First cam mechanism includes the first cam 53 and the first actuated by cams motor 52 for driving the first cam rotation;
The described cup mechanism that pushes away includes push pedal 54, the first guide post 58, (the first back-moving spring 55 and wedge shape pushing block 56;
First riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole;Wedge Shape pushing block and push pedal are separately positioned on leading section and the rearward end of the first guide post;(the first back-moving spring is sleeved on the first guide post On;
First cam is contacted with push pedal;During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape When pushing block advances, the fixture 57 of clamping reaction cup can be pushed open so that reaction cup departs from fixture, realize losing cup.
The first described guide post is 2, and described pilot hole is 2.
Automatically lose cup device and also include Diu Bei testing agency, described Diu Bei testing agency includes being arranged on the first riser Static inducting part and be arranged on the movable trigger unit pushing away on cup mechanism.
Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable Trigger unit and static inducting part are respectively light barrier 60 and photoelectricity to penetrating detection module 61.
Automatically lose the rotation platform that cup device also includes for installs fixture, described fixture is multiple, is arranged on rotation On platform.
Lose a glass process:Lose before a glass process starts, lose cup device and be in original state, now wedge shape pushing block is in the first reset bullet It is in retraction position, the initial position of retraction position position wedge shape pushing block in the presence of spring;
Lose a glass process to comprise the following steps:
Step 1:Alignment procedures:The wedge shape pushing block pushing away cup mechanism is directed at the fixture being clamped with reaction cup;
Step 2:Push away a glass step:Start the first actuated by cams motor, first actuated by cams Motor drive the first cam rotates, First cam promotes push pedal to advance, and wedge shape pushing block and push pedal link, and wedge shape pushing block is pushed fixture open and reached and pushes away cup position so that reaction cup Depart from the clamping of fixture, complete to lose cup;
Step 3:Reset process:The rear half-turn that first actuated by cams motor shaft rotates a circle is the first cam return action, Wedge shape pushing block returns to initial position in the presence of (the first back-moving spring, and the sensing chip being now fixed on pushing block and optocoupler pass Sensor senses, motor stalls;Lose cup to terminate;Initiate to push away a glass step Deng Wait Order next time;
Detect the position of wedge shape pushing block using Diu Bei testing agency;
When wedge shape pushing block is in initial position, the static inducting part being arranged on the first riser can sense and be arranged on Push away the movable trigger unit on cup mechanism;
When wedge shape pushing block is in and pushes away glass position, described static inducting part can not sense movable trigger unit.
Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable Trigger unit and static inducting part are respectively light barrier 60 and photoelectricity to penetrating detection module 61.
Fixture is multiple, is arranged on rotation platform and along rotation platform circumferentially, by controlling rotary flat The anglec of rotation of platform makes wedge shape pushing block and grip alignment.
The lower section of wedge shape pushing block is additionally provided with hopper 59, for the reaction cup guiding collecting box that will abandon.
Rotation platform includes support, the motor 571 of rotating disk 48, arc carrier 50 and driving rotating disk and gear 561;
Rotating disk is arranged on support, rotating disk is endless member, and the internal ring side of rotating disk is provided with for being adapted to described gear Double wedge;Gear is arranged in the rotating shaft of motor;
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system;On arc carrier It is provided with the fixture 57 for accommodating reaction cup;
Arc carrier is provided with the Magnet fixed block 551 with Magnet;First Hall element 521 is fixed with support, Hall element is concordant with the height of Magnet.
Support is provided with for detecting the reaction cup detection sensor 531 that reaction cup whether there is.
Described Hall element is multiple, being arranged circumferentially on support along rotating disk.
Described support includes support ring and the many support columns 541 for supporting support ring.
Supporting column bottom is provided with firm banking 46.
Reaction cup rotating mechanism is also called rotation platform, and for driving reaction cup to switch in each module, this platform has Internal-gear type rotary turnplate mechanism, the arc carrier of placing response cup;
The arc carrier of described placing response cup is fixed on rotating disk, and fixture is used for clamping reaction cup, instrument (i.e. chemistry Luminous tester) run when, manually reaction cup place arc carrier on, clamp reaction cup is it is ensured that moving in a circle When reaction cup do not rock;
Described Hall element is used for detecting that reaction cup reaches the position of each station;Described reaction cup detection sensing Device is used for detecting whether arc carrier has reaction cup.
Fluid injection/evenly mixing device (evenly mixing device is also known as agitating device) includes the second riser 71, cam flat pushing mechanism and is used for Fluid injection/evenly mixing device for reaction cup fluid injection;
Cam flat pushing mechanism include the second cam 78, for driving cam rotation the second actuated by cams motor 79, pushing block, Second guide post 80, second back-moving spring 77;
Described fluid injection/evenly mixing device includes liquid injection pipe fixed plate 73 and the fluid injection being vertically fixed in liquid injection pipe fixed plate Pipe 74;
Second riser is provided with pilot hole, and guide post is inserted in pilot hole;Liquid injection pipe fixed plate and pushing block are respectively provided with Leading section and rearward end in the second guide post;Back-moving spring is sleeved on the second guide post;
Second cam is contacted with pushing block;During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe Travel forward, when reaching foremost, start fluid injection, after the completion of fluid injection, liquid injection pipe fixed plate and liquid injection pipe return reset.
The second described guide post is 2, and described pilot hole is 2.
Fluid injection/the evenly mixing device of described chemical luminescence detector also includes position detecting mechanism, the described detection that puts in place Mechanism includes the static inducting part being arranged on riser and is arranged on the movable trigger unit pushing away on cup mechanism.
Movable trigger unit and static inducting part are respectively magnetic sheet 75 and the second Hall element 76, or, described Movable trigger unit and static inducting part be respectively light barrier and photoelectricity to penetrating detection module.
Baffle plate 72 is additionally provided with riser, baffle plate is located at the lower section of liquid injection pipe fixed plate, baffle plate is provided with for for liquid injection pipe The bar shaped guide hole of guided in translation.
Fluid injection/the evenly mixing device of chemical luminescence detector also includes the rabbling mechanism below baffle plate, rabbling mechanism bag Include rabbling mechanism fixed plate 83, stirring motor 81 and the sleeve 82 for entangling reaction cup.
Described rabbling mechanism is driven by Z axis drive mechanism.
The reaction cup rear stirrer structure that puts in place moves upwards, and reaction cup is pressed into stirring sleeve under the stop of baffle plate, now needs Will be to reaction cup fluid injection, the second actuated by cams motor action, drive fluid injection/evenly mixing device to advance, after putting in place, be reaction cup note Liquid.After the completion of fluid injection, the second actuated by cams motor does not reoperate, and in the presence of back-moving spring, fluid injection/evenly mixing device resets. After liquid liquid enters to finish, stirring motor starts drive stirring sleeve and carries out high-speed motion, to reach the effect of liquid blending.
Incubating device includes vertical plate 64 and the incubation block 69 being arranged on vertical plate;The outer wall of incubation block is provided with thermal insulation board 70;It is provided with heater in incubation block.
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
Z axis straight-line motion mechanism be lead screw transmission mechanism, include the 3rd motor 62, screw mandrel 68, screw mandrel contiguous block 65 and erect Straight guide post 66;
The top of vertical plate and bottom are respectively equipped with upper plate 63 and lower shoe 67, and being vertically directed bar is 2 so that being incubated Block runs more steady.
The top and bottom being vertically directed bar are separately fixed on upper plate and lower shoe;Screw mandrel contiguous block is arranged on vertically On guide post, the 3rd motor is fixed on upper plate;The upper end of screw mandrel connects motor, and the lower end connection wire rod of leading screw connects Block;Incubation block is fixed on screw mandrel contiguous block;During the 3rd motor rotation, incubation block edge is driven to be vertically directed bar elevating movement.
When needing the sample in reaction cup is incubated, incubation block liter is got up, after the completion of incubation, block will be incubated Lower resigning.Incubation block top is provided with multiple holes for accommodating reaction cup.
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly 105, darkroom 92 and PMT reading module 93;
Described bearing is provided with the guide rail 94 of vertical direction;Lift drive mechanism includes the 4th motor 89, drive mechanism With guide rail contiguous block 95;Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, darkroom and PMT Reading module is connected;4th motor passes through drive mechanism and guide rail contiguous block drives PMT reading module and darkroom to rise along guide rail Fall motion;
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly;During detection, treat The reaction cup of detection is located in darkroom, and the column 91 that is in the light is used for being in the light;
Z-axis transmission mechanism is provided with bearing, fluid injection/discharge opeing needle assembly is arranged on bearing by Z-axis transmission mechanism.
Drive mechanism is lead screw transmission mechanism.
The 4th described motor is motor.Motor connection block 90 is used for and leading screw cooperation.During detection, reaction cup is placed in In darkroom, PMT module is detected and reading to the liquid in reaction cup.Fluid injection/discharge opeing needle assembly decline after to reaction cup plus Liquid and discharge opeing operation.PMT module is docked with darkroom, and both are located at sustained height (being located at same level position).
When reactant reaches this system, fluid injection/discharge opeing needle assembly declines the injection substrate toward in reaction cup and produces signal, PMT Reading module rises to close up again and carries out signal detection and output data, and in the process, light-baffling device (darkroom) is that system provides Dark room conditions.
Darkroom module is fixed in PMT reading module, and PMT reading module is used for carrying out reading detection, darkroom to reactant Module completely cuts off the accuracy of the ambient guarantee reading of reactant;Fluid injection/discharge opeing needle assembly includes liquid injection pipe fixed plate, fluid injection Pipe, discharging tube, influidic pipe fixed block, this assembly is used for producing signal to reactant injection substrate, after discharging tube is used for reading Reaction cup carries out waste liquid exclusion;Fluid injection realizes accurate liquid feeding by plunger displacement pump, and plunger displacement pump is a kind of energy liquid with precise control sample-adding The device of amount;This assembly is existing mature modules.

Claims (8)

1. a kind of chemical luminescence detector it is characterised in that include base, rotation platform, liquid taking device, cleaning device, fluid injection/ Evenly mixing device, incubating device, reading plotter and lose cup device;
Rotation platform is arranged on the central authorities of base, liquid taking device, cleaning device, fluid injection/evenly mixing device, incubating device, reading dress Put and lose cup device to be all arranged on base around rotation platform;
Rotation platform includes support, the motor (571) of rotating disk (48), arc carrier (50) and driving rotating disk and gear (561);
Rotating disk is arranged on support, and rotating disk is endless member, and the internal ring side of rotating disk is provided with the double wedge for being adapted to described gear; Gear is arranged in the rotating shaft of motor;
Arc carrier is fixed on rotating disk by arc carrier vertical columns, can be with rotating disk synchronous axial system;Arc carrier is provided with For accommodating the fixture (57) of reaction cup;
Arc carrier is provided with the Magnet fixed block (551) with Magnet;First Hall element (521) is fixed with support, First Hall element is concordant with the height of Magnet;
The first described Hall element is multiple, being arranged circumferentially on support along rotating disk;
The first described Hall element is used for detecting that reaction cup reaches the position of each station;
This rotation platform putting cup position, take liquid level, liquid blending position, incubation position, cleaning position, reading position and lose cup position and be respectively provided with There is the first Hall element, reach the position of each station for sensing reaction cup, Magnet follows the work in motor for the rotary turnplate With under circle, when turntable rotation to relevant position, Magnet is sensed with Hall element, rotating disk stop, will be at this Position is detected operation accordingly.
2. chemical luminescence detector according to claim 1 it is characterised in that:
Including the second riser (71), cam flat pushing mechanism and for for reaction cup fluid injection mechanism for filling liquid;
Cam flat pushing mechanism include the second cam (78), for driving cam rotation the second actuated by cams motor (79), pushing block, Second guide post (80), second back-moving spring (77);
Described mechanism for filling liquid includes liquid injection pipe fixed plate (73) and the liquid injection pipe (74) being vertically fixed in liquid injection pipe fixed plate;
Riser is provided with pilot hole, and guide post is inserted in pilot hole;Liquid injection pipe fixed plate and pushing block are separately positioned on guide post Leading section and rearward end;Back-moving spring is sleeved on guide post;
Second cam is contacted with pushing block;During the second cam rotation, the second cam can drive liquid injection pipe fixed plate and liquid injection pipe forward Motion.
3. chemical luminescence detector according to claim 2 is it is characterised in that be additionally provided with baffle plate (72) on the second riser, Baffle plate is located at the lower section of liquid injection pipe fixed plate, and baffle plate is provided with for the bar shaped guide hole for liquid injection pipe guided in translation;
Fluid injection/evenly mixing device includes rabbling mechanism, and rabbling mechanism includes rabbling mechanism fixed plate (83), stirring motor (81) and uses In the sleeve (82) entangling reaction cup.
4. chemical luminescence detector according to claim 1 is it is characterised in that incubating device includes vertical plate (64) and sets Put the incubation block (69) on vertical plate;The outer wall of incubation block is provided with thermal insulation board (70);It is provided with heater in incubation block;
Described incubation block is connected with vertical plate by Z axis straight-line motion mechanism.
5. chemical luminescence detector according to claim 4 is it is characterised in that Z axis straight-line motion mechanism is screw rod transmission Mechanism, including the 3rd motor (62), screw mandrel (68), screw mandrel contiguous block (65) be vertically directed bar (66);
The top of vertical plate and bottom are respectively equipped with upper plate (63) and lower shoe (67), the described upper end being vertically directed bar and Lower end is separately fixed on upper plate and lower shoe;Screw mandrel contiguous block is arranged on and is vertically directed on bar, and motor is fixed on On base plate;The upper end of screw mandrel connects the 3rd motor, the lower end connection wire rod contiguous block of leading screw;Incubation block is fixed on screw mandrel contiguous block On;During the 3rd motor rotation, drive incubation block along being vertically directed bar elevating movement, be vertically directed bar and be 2.
6. chemical luminescence detector according to claim 1 it is characterised in that
Reading plotter includes bearing, lift drive mechanism, fluid injection/discharge opeing needle assembly (105), darkroom (92) and PMT reading module;
Described bearing is provided with the guide rail of vertical direction;Lift drive mechanism includes the 4th motor (89), drive mechanism and leads Rail contiguous block (95);Guide rail contiguous block is arranged on guide rail, and PMT reading module is fixed on guide rail contiguous block, and darkroom is read with PMT Digital-to-analogue block is connected;Motor drives PMT reading module and darkroom to make elevating movement along guide rail by drive mechanism and guide rail contiguous block;
Fluid injection/discharge opeing needle assembly is arranged on bearing, and darkroom is located at the underface of fluid injection/discharge opeing needle assembly;During detection, to be detected Reaction cup be located at darkroom in.
7. chemical luminescence detector according to claim 1 it is characterised in that lose cup device include the first riser (51), Cam mechanism and push away cup mechanism;
Cam mechanism includes the first cam (53) and the first actuated by cams motor (52) for driving the first cam rotation;
The described cup mechanism that pushes away includes push pedal (54), the first guide post (58), (the first back-moving spring (55) and wedge shape pushing block (56);
First riser is provided with for the pilot hole for pushing away cup mechanism guiding, and the first guide post is inserted in pilot hole;Wedge shape pushes away Block and push pedal are separately positioned on leading section and the rearward end of the first guide post;Back-moving spring is sleeved on the first guide post;
First cam is contacted with push pedal;During the first cam rotation, the first cam can drive and push away cup mechanism and travel forward, wedge shape pushing block During advance, the fixture (57) of clamping reaction cup can be pushed open so that reaction cup departs from fixture.
8. chemical luminescence detector according to claim 7 also includes losing a glass testing machine it is characterised in that losing cup device Structure, described Diu Bei testing agency include the static inducting part that is arranged on riser and being arranged on push away movable on cup mechanism Trigger unit;Movable trigger unit and static inducting part are respectively magnetic sheet and Hall element, or, described is movable Trigger unit and static inducting part are respectively light barrier (60) and photoelectricity to penetrating detection module (61).
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CN106405132A (en) * 2016-08-26 2017-02-15 深圳市库贝尔生物科技股份有限公司 Chemiluminescence measuring system
CN108196076A (en) * 2017-07-11 2018-06-22 赛纳生物科技(北京)有限公司 A kind of kit and its reagent extraction mechanism
CN109142708A (en) * 2018-09-02 2019-01-04 广州源起健康科技有限公司 A kind of Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument
CN109580592A (en) * 2017-09-28 2019-04-05 深圳市新产业生物医学工程股份有限公司 Measuring chamber, the working method of measuring chamber, measuring chamber chemical luminescent detecting method and chemiluminescence detector
CN109580967A (en) * 2019-01-16 2019-04-05 广州万孚生物技术股份有限公司 Optical pickup and detection system
CN110579455A (en) * 2019-08-26 2019-12-17 伊普希龙(天津)科技有限公司 Fluorescence spectrophotometer with heat abstractor
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CN117969417A (en) * 2024-03-29 2024-05-03 江苏南晶红外光学仪器有限公司 Optical glass light transmission detection device
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* Cited by examiner, † Cited by third party
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CN106405132B (en) * 2016-08-26 2018-05-22 深圳市库贝尔生物科技股份有限公司 A kind of chemical luminescent detecting system
CN106405132A (en) * 2016-08-26 2017-02-15 深圳市库贝尔生物科技股份有限公司 Chemiluminescence measuring system
CN108196076A (en) * 2017-07-11 2018-06-22 赛纳生物科技(北京)有限公司 A kind of kit and its reagent extraction mechanism
US11016029B2 (en) 2017-09-28 2021-05-25 Shenzhen New Industries Biomedical Engineering Co., Ltd. Measuring chamber, working method of measuring chamber, chemiluminescence measurement method of measuring chamber and chemiluminescence detector
CN109580592A (en) * 2017-09-28 2019-04-05 深圳市新产业生物医学工程股份有限公司 Measuring chamber, the working method of measuring chamber, measuring chamber chemical luminescent detecting method and chemiluminescence detector
CN109580592B (en) * 2017-09-28 2021-10-08 深圳市新产业生物医学工程股份有限公司 Measuring chamber and working method thereof, chemiluminescence measuring method and luminescence detector
CN109142708B (en) * 2018-09-02 2023-01-24 广州源起健康科技有限公司 Full-automatic magnetic bead time-resolved fluorescence immunoassay appearance
CN109142708A (en) * 2018-09-02 2019-01-04 广州源起健康科技有限公司 A kind of Full-automatic magnetic beads time-resolved fluorescence immunoassay instrument
CN109580967A (en) * 2019-01-16 2019-04-05 广州万孚生物技术股份有限公司 Optical pickup and detection system
CN109580967B (en) * 2019-01-16 2024-05-31 广州万孚生物技术股份有限公司 Optical acquisition device and detection system
CN110579455A (en) * 2019-08-26 2019-12-17 伊普希龙(天津)科技有限公司 Fluorescence spectrophotometer with heat abstractor
CN116948816A (en) * 2023-06-06 2023-10-27 仲恺农业工程学院 Superoxide dismutase tolerance detection device and method
CN116948816B (en) * 2023-06-06 2024-05-07 仲恺农业工程学院 Superoxide dismutase tolerance detection device and method
CN117969417A (en) * 2024-03-29 2024-05-03 江苏南晶红外光学仪器有限公司 Optical glass light transmission detection device

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