CN103245790B - Analyzer for vaginal secretion - Google Patents

Analyzer for vaginal secretion Download PDF

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Publication number
CN103245790B
CN103245790B CN201210031755.9A CN201210031755A CN103245790B CN 103245790 B CN103245790 B CN 103245790B CN 201210031755 A CN201210031755 A CN 201210031755A CN 103245790 B CN103245790 B CN 103245790B
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China
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illumination
vaginal fluid
fluid analyser
light
light source
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CN201210031755.9A
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CN103245790A (en
Inventor
王淳玉
王红明
凌燕
张丽梅
郭丽红
张永威
王加义
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BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY CO., LTD.
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BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY Co Ltd
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Abstract

The invention provides an analyzer for vaginal secretion. The analyzer comprises a conveying mechanism, a sample feeding arm mechanism, an X-ray machine head mechanism and a feeding mechanism, wherein the conveying mechanism consists of a conveyor belt and a solenoid valve and is used for controlling a testing sample to enter into different test processes; the sample feeding arm mechanism is arranged above the conveying mechanism and is used for automatically adding a color developing agent to the testing sample; the X-ray machine head mechanism is arranged at one end of the conveyor belt and is used for performing color detection on the testing sample; and the feeding mechanism is arranged at one end of the conveyor belt, close to the X-ray machine head mechanism, and is used for automatically feeding the testing sample into the conveyor belt after the sample is placed. The analyzer for the vaginal secretion is high in detection efficiency, degree of automation, detection precision and repeatability, and simple to operate, and realizes friendly human-computer interaction.

Description

Vaginal fluid analyser
Technical field
The present invention relates to a kind of detection analyser, be specifically related to a kind of vaginal fluid analyser.
Background technology
Vaginal fluid analyser is that the extracorporeal diagnostic instrument being integrated is controlled in light harvesting, machinery, electronics, robotization.Vaginal fluid analyser is mainly used in the fast detecting of hydrogen peroxide in vaginal secretion, neuraminidase, leucocyte lipase, beta-glucuronidase enzyme, coagulase.The five-item combined mensuration kit of this instrument and aerobic bacteria vaginitis/bacterial vaginosis BV is when detecting positive and negative vagina liquid, and because lesion degree is different, reacting hole can present different color reactions.By distinguishing color relation, can obtain the result of yin and yang attribute.This analyser adopts sensitive component to accept catoptrical mode and measures color value.Analyser reacts by different colours corresponding to contrast yin and yang attribute, draws the result of yin and yang attribute.
Vaginal fluid analyser is the professional and complete instrument for 5 AV/BV detection kit of vaginal fluid detection.There is following some difference in existing similar detecting instrument and vaginal fluid analyser:
1. accuracy of detection and repeatability are poor, are difficult to meet the requirement of clinical practice;
2. detection efficiency is lower, can not accomplish that sample detects with arriving at any time;
3. test item there are differences, and not exclusively possesses the measuring ability of hydrogen peroxide, neuraminidase, leucocyte lipase, beta-glucuronidase enzyme, coagulase.
Summary of the invention
(1) technical matters that will solve
The object of this invention is to provide a kind of accuracy of detection, automaticity is high, really accomplish with the vaginal fluid analyser to detecting at any time and can possessing hydrogen peroxide, neuraminidase, leucocyte lipase, beta-glucuronidase enzyme, five measuring abilities of coagulase simultaneously.
(2) technical scheme
In order to solve the problems of the technologies described above, the invention provides a kind of vaginal fluid analyser, comprising:
Connecting gear, it comprises travelling belt and electromagnetic valve, for controlling test sample book, enters different testing processs;
Sample arm mechanism, is located at described connecting gear top, for automatically adding developer to test sample book;
Light head section mechanism, is located at one end of described travelling belt, for test sample book is carried out to color detection; And
Feeding mechanism, is located at described travelling belt near one end of light head section mechanism, for after putting in test sample book, it is sent into described travelling belt automatically.
Preferably, described smooth head section mechanism comprises color detection plate and is located at respectively the light source board of described color detection plate both sides; A plurality of illumination perforations that described light source board is provided with circuit board, is arranged in a row, and be connected on circuit board and position corresponding to a plurality of light sources of described a plurality of illumination perforations; Described color detection plate is provided with circuit board, a plurality of incidence holes corresponding with described a plurality of illumination perforations, and be fixed on circuit board and position corresponding to a plurality of color sensors of described a plurality of incidence holes.
Preferably, described color detection plate lower end is also provided with protuberance; Described protuberance has two sides and a bottom surface, and described side is parallel with the illumination perforation on two light source boards respectively, and described incidence hole runs through protuberance and receives reflected light from described bottom surface.
Preferably, the angle between described illumination perforation and incidence hole is 45 degree.
Preferably, described light source is white light LEDs.
Preferably, described smooth head section mechanism adopts photoelectric integral method to detect color, and adopts blackening process, increases diaphragm mouth.
Preferably, the light source on described each light source board, the quantity of illumination perforation are 5, and incidence hole, color sensor quantity on corresponding described color detection plate are also 5.
Preferably, the five-item combined mensuration reagent device of this light head section mechanism and aerobic bacteria vaginitis/bacterial vaginosis BV is supporting, and described 5 illumination perforations and incidence hole are corresponding to 5 reagent wells on described reagent device; The diameter of described illumination perforation is less than the diameter of reagent wells; The diameter of described illumination perforation equals the diameter of incidence hole.
Preferably, described sample arm mechanism comprises two sample arms, and each sample arm can move with vertical direction both direction in the horizontal direction; There are in the horizontal direction three optocoupler location, comprise cleaning positions, liquid feeding position and imbibition position; There are in the vertical direction two zero-bits and liquid feeding position.
Preferably, described feeding mechanism comprises linear electric motors, block and optocoupler.
(3) beneficial effect
1. vaginal fluid analyser of the present invention is by adopting automatic feeding mechanism, connecting gear and sample arm mechanism, detection efficiency and automaticity improve, do not need by batch etc. to be tested, can really accomplish that with to detecting at any time, maximum per hour can detect 100.
2. adopt ray machine head and the high-precision photoelectric integration color detection technology of particular design, accuracy of detection and repeatability are higher, can meet clinical practice requirement completely.
3. possess the measuring ability of hydrogen peroxide, neuraminidase, leucocyte lipase, beta-glucuronidase enzyme, coagulase, simple to operate, man-machine interaction is friendly simultaneously.
Accompanying drawing explanation
Fig. 1 is the structural drawing of vaginal fluid analyser one embodiment of the present invention;
Fig. 2 is the front view of ray machine header structure in vaginal fluid analyser one embodiment of the present invention;
Fig. 3 is the upward view of ray machine header structure in vaginal fluid analyser one embodiment of the present invention;
Fig. 4 be in vaginal fluid analyser one embodiment of the present invention ray machine header structure vertical view;
Fig. 5 is the schematic diagram of the five-item combined mensuration reagent device of aerobic bacteria vaginitis/bacterial vaginosis BV;
Fig. 6 is the structural drawing of feeding mechanism in vaginal fluid analyser one embodiment of the present invention;
Fig. 7 is the structural drawing of connecting gear in vaginal fluid analyser one embodiment of the present invention;
Fig. 8 is the structural drawing of sample arm mechanism in vaginal fluid analyser one embodiment of the present invention.
Wherein, 100: connecting gear; 200: sample arm mechanism; 300: light head section mechanism; 400: feeding mechanism; 1: light source board; 11: circuit board; 12: light source; 13: illumination perforation; 2: color detection plate; 21: circuit board; 22: protuberance; 221,222: side; 223: bottom surface; 23: enter perforation; 24: fixed orifice; 3: the five-item combined mensuration reagent device of oxygen bacterium vaginitis/bacterial vaginosis BV; 31: reagent wells.
Embodiment
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following examples are used for illustrating the present invention, but do not limit the scope of the invention.
As shown in Figure 1, vaginal fluid analyser of the present invention, comprising: connecting gear (100), and it comprises travelling belt and electromagnetic valve, for controlling test sample book, enters different testing processs; Sample arm mechanism (200), is located at described connecting gear top, for automatically adding developer to test sample book; Light head section mechanism (300), is located at one end of described travelling belt, for test sample book is carried out to color detection; And feeding mechanism (400), be located at described travelling belt near one end of light head section mechanism, for after putting in test sample book, it is sent into described travelling belt automatically.
As shown in Figure 2 to 4, be respectively front view, upward view and the vertical view of light head section mechanism in vaginal fluid analyser one embodiment of the present invention.Smooth head section mechanism of the present invention, comprises color detection plate 2 and is located at respectively the light source board 1 of described color detection plate 2 both sides; 5 illumination perforations 13 that described light source board 1 is provided with circuit board 11, is arranged in a row, and be connected on circuit board 11 and position corresponding to 5 white LED light sources 12 of described 5 illumination perforations 13; Described color detection plate 2 is provided with circuit board 21,5 incidence holes 23 corresponding with described 5 illumination perforations 13, and be fixed on circuit board 21 and position corresponding to 5 color sensors of described 5 incidence holes 23.
In the present embodiment, described color detection plate 2 lower ends are also provided with protuberance 22; Described protuberance 22 has two sides 221,222 and a bottom surface 223, and described side 221,222 is parallel with the illumination perforation 13 on two light source boards 1 respectively, and described incidence hole 23 runs through protuberance 22 and receives reflected light from described bottom surface 223.Angle between described illumination perforation 13 and incidence hole 23 is 45 degree, and the diameter of described illumination perforation 13 equals the diameter of incidence hole 23.
This light head section mechanism can detect 5 colors that diameter is the liquid in 3mm hole on reagent device (as shown in Figure 5) accurately, meets the requirement that analyser quick and precisely detects.Four holes of light head section mechanism surrounding are fixed orifice 24, and light head section mechanism is connected with analyser by fixed orifice 24, thereby form the metering system of optics.Illumination perforation 13 is the light hole of LED light, the size in hole directly determines the size of hot spot, and for fear of interference, total spot size of the illumination perforation 13 of both sides is in hole 31 corresponding to reagent device, the diameter of hot spot is 2.8mm simultaneously, is less than the size of reagent wells 31.Middle entrance pupil is that reflected light is to the path of sensor, in order to eliminate multiple reflections and the parasitic reflection of light, the diameter 2.8mm of entrance pupil 23, just in time can be detected by color sensor the color region in reagent device, has avoided again other spuious photoelectricity to enter simultaneously.
Angle between illumination perforation 13 and incidence hole 23 is 45 degree, thereby the angle between installed surface LED installed surface and color sensor is 45° angle, thereby has guaranteed the detection geometric condition of 0/45 °, so that detect more accurate.
Light head section mechanism 300 is color detection structures of vaginal fluid analyser.Method for detecting color adopts photoelectric integration formula method, adopts 5 color detection modules to detect respectively hydrogen peroxide, neuraminidase, leucocyte lipase, beta-glucuronidase enzyme, the coagulase of test sample book.Light head section mechanism adopts blackening process, avoids parasitic reflection, increases light Lan Kou simultaneously, suppresses veiling glare.
In the present embodiment, feeding mechanism as shown in Figure 6.Feeding mechanism 400 is mainly realized the function that sample is put into the automatic transmission after instrument.When test sample book is put into from entrance and put in place, feed arrangement is pushed into connecting gear 100 test sample book automatically.Feed arrangement comprises linear electric motors, block and optocoupler.Feeding mechanism 400, by back and forth movement, is realized the automatic feeding process of test sample book.
Connecting gear 100 is motions that Realization analysis instrument detects, and structure as shown in Figure 7.This connecting gear 100 adopts the mode of Timing Belt and electromagnetic valve to realize.After test sample book is put on travelling belt, travelling belt carries test sample book to thermostatic bath district, and after the wait sample reaction time arrives, electromagnetic valve is opened, and test sample book enters next testing process.The reaction time not then, electromagnetic valve is closed, test sample book rests on after baffle plate.
Sample arm mechanism 200 adds function automatically for what realize developer, and structure as shown in Figure 8.Have two sample arms, sample arm has the motion of both direction, horizontal direction and vertical direction.There are in the horizontal direction three optocoupler location, cleaning positions, liquid feeding position, imbibition position.There are in the vertical direction two zero-bits and liquid feeding position.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, do not departing under the prerequisite of the technology of the present invention principle; can also make some improvement and replacement, these improvement and replacement also should be considered as protection scope of the present invention.

Claims (8)

1. a vaginal fluid analyser, is characterized in that, comprising:
Connecting gear (100), it comprises travelling belt and electromagnetic valve, for controlling test sample book, enters different testing processs;
Sample arm mechanism (200), is located at described connecting gear top, for automatically adding developer to test sample book;
Light head section mechanism (300), is located at one end of described travelling belt, for test sample book is carried out to color detection; And
Feeding mechanism (400), is located at described travelling belt near one end of light head section mechanism, for after putting in test sample book, it is sent into described travelling belt automatically;
Wherein said smooth head section mechanism (300) comprises color detection plate (2) and is located at respectively the light source board (1) of described color detection plate (2) both sides; A plurality of illumination perforations (13) that described light source board (1) is provided with circuit board (11), is arranged in a row, and be connected to the upper and position of circuit board (11) corresponding to a plurality of light sources (12) of described a plurality of illumination perforations (13); Described color detection plate (2) is provided with circuit board (21), a plurality of incidence holes (23) corresponding with described a plurality of illumination perforations (13), and is fixed on the upper and position of circuit board (21) corresponding to a plurality of color sensors of described a plurality of incidence holes (23);
Angle between described illumination perforation (13) and incidence hole (23) is 45 degree.
2. vaginal fluid analyser as claimed in claim 1, is characterized in that, described color detection plate (2) lower end is also provided with protuberance (22); Described protuberance (22) has two sides (221,222) and one bottom surface (223), described side (221,222) parallel with the illumination perforation (13) on two light source boards (1) respectively, described incidence hole (23) runs through protuberance (22) and receives reflected light from described bottom surface (223).
3. vaginal fluid analyser as claimed in claim 1, is characterized in that, described light source (12) is white light LEDs.
4. vaginal fluid analyser as claimed in claim 1, is characterized in that, described smooth head section mechanism (300) adopts photoelectric integral method to detect color, and adopts blackening process, increases diaphragm mouth.
5. vaginal fluid analyser as claimed in claim 1, it is characterized in that, light source (12) on described each light source board (1), the quantity of illumination perforation (13) are 5, and incidence hole (23), color sensor quantity on corresponding described color detection plate (2) are also 5.
6. vaginal fluid analyser as claimed in claim 5, it is characterized in that, the five-item combined mensuration reagent device of this light head section mechanism and aerobic bacteria vaginitis/bacterial vaginosis BV (3) is supporting, and described 5 illumination perforations (13) and incidence hole (23) are corresponding to 5 reagent wells (31) on described reagent device; The diameter of described illumination perforation (13) is less than the diameter of reagent wells (31); The diameter of described illumination perforation (13) equals the diameter of incidence hole (23).
7. vaginal fluid analyser as claimed in claim 1, is characterized in that, described sample arm mechanism (200) comprises two sample arms, and each sample arm can move with vertical direction both direction in the horizontal direction; There are in the horizontal direction three optocoupler location, comprise cleaning positions, liquid feeding position and imbibition position; There are in the vertical direction two zero-bits and liquid feeding position.
8. vaginal fluid analyser as claimed in claim 1, is characterized in that, described feeding mechanism (400) comprises linear electric motors, block and optocoupler.
CN201210031755.9A 2012-02-13 2012-02-13 Analyzer for vaginal secretion Active CN103245790B (en)

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Publication number Priority date Publication date Assignee Title
CN105866116B (en) * 2016-05-27 2019-03-29 天津果实科技有限公司 The device of one-to-one detection is carried out to test paper using color sensor
CN106018395B (en) * 2016-05-27 2019-03-29 天津果实科技有限公司 A kind of device being acquired detection to test paper using color sensor
CN106338608B (en) * 2016-08-31 2018-08-07 迪瑞医疗科技股份有限公司 A kind of Gynecological secretion automatic checkout equipment
CN109520930A (en) * 2018-12-29 2019-03-26 苏州汶颢微流控技术股份有限公司 A kind of elisa assay instrument
CN110220890A (en) * 2019-05-22 2019-09-10 济南百博生物技术股份有限公司 Vaginal fluid detector
CN110954488A (en) * 2019-12-30 2020-04-03 长沙协大生物科技有限公司 Vaginal secretion sample detection device and method based on color recognition

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Address after: 102200 No. 6, Spark Street, Changping District science and Technology Park, Beijing

Patentee after: BEIJING ZHONGSHENG JINYU DIAGNOSIS TECHNOLOGY CO., LTD.

Address before: 102200 Beijing city Changping District Road North white floating technology building six layer 606

Patentee before: Beijing Zhongsheng Jinyu Diagnosis Technology Co., Ltd.