CN203672885U - Automatic circulation sample loading device of test tube coating method radioimmunoassay analyzer - Google Patents
Automatic circulation sample loading device of test tube coating method radioimmunoassay analyzer Download PDFInfo
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- CN203672885U CN203672885U CN201420050917.8U CN201420050917U CN203672885U CN 203672885 U CN203672885 U CN 203672885U CN 201420050917 U CN201420050917 U CN 201420050917U CN 203672885 U CN203672885 U CN 203672885U
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- reagent bottle
- needle
- syringe needle
- cleaning fluid
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Abstract
Disclosed is an automatic circulation sample loading device of a test tube coating method radioimmunoassay analyzer. The first station of the a frame is provided with a labeled antigen fluid feeding pump device, the second station of the frame is provided with a cleaning fluid feeding pump device, the third station of the frame is provided with a cleaning fluid extracting device, and the fourth station of the frame is provided with a radioimmunoassay analyzer detecting device; a tray is provided with a plurality of reagent bottle inserting slots which are arranged orderly; the sample loading needles of the labeled antigen fluid feeding pump device as well as the cleaning fluid feeding pump device, the liquid sucking needle of the cleaning fluid extracting device and the detecting needle of the radioimmunoassay analyzer detecting device are arranged above the reagent bottle inserting slots and correspond to the reagent bottle inserting slots of the tray in number and arrangement; the fluid sucking needle of the cleaning fluid extracting device is mounted onto the needle rest of the third station, and the needle rest of the third station is mounted on the frame through a lifting mechanism; the detecting needle of the radioimmunoassay analyzer detecting device is fixed onto the needle rest of the fourth station, and the fourth station is provided with a jacking mechanism under the rail of a circulating moving device; the jacking rods of the jacking mechanism are arranged under the reagent bottle inserting slots of the tray and correspond to the reagent bottle inserting slots in number; the bottom of every reagent bottle inserting slot of the tray is provided with a through hole which corresponds to the corresponding jacking rod in size and position. The automatic circulation sample loading device of the test tube coating method radioimmunoassay analyzer is simple in structure, high in practicality and easy to operate and can solve the sample loading, washing and extracting testing process of a radioimmunoassay test tube coating method experiment.
Description
Technical field
The utility model relates to the coated method of a kind of test tube and puts and exempt from instrument automatic cycle sample adding device.
Background technology
Radioimmunoassay experiment has two kinds of modes at present, and one is adding sample, labelled antigen, and corresponding antibody is added in test tube, then incubation, then add separation agent, and centrifugal, free part is taken out.Be put into y-counter again and go to measure, because centrifugal need hydro-extractor, batch samples can not once complete, and efficiency is low, another kind is to adopt corresponding antibodies to be coated on test tube bottom, add again then incubation of sample and labelled antigen, after completing, question response washes free unreacted part off with cleaning fluid, use again γ-counter measures, this method is the coated method of radio-immunity test tube, although coated method does not need with hydro-extractor, but coated method step is many, manually sample and labelled antigen need to be added in the coated test tube of coated antibody, put into incubator incubation, after completing, question response adds again cleaning fluid, wash unreacted free fraction, then with negative pressure pump or attractor, cleaning fluid is extracted out, clean two to three times, , on the one hand such application of sample often, application of sample speed is slow, on the other hand, because sample has certain radiant quantity, handling time is oversize, easily there is the symptoms such as tired in people, cause Efficiency Decreasing, and easily there is maloperation.Just because of this, radioimmunoassay experiment is slowly replaced by luminous detection, but the requirement of luminous detection sensitivity is high, and instrument and reagent costliness, therefore cause testing cost high.
Utility model content
The purpose of this utility model be for the deficiencies in the prior art provide a kind of realize in the coated test tube that automatically labelled antigen is added to coated antibody and automatically wash the coated method of the test tube detecting again after unreacted free fraction put and exempt from instrument automatic cycle sample adding device.
The utility model is achieved through the following technical solutions above-mentioned purpose:
The coated method of a kind of test tube is put and is exempted from instrument automatic cycle sample adding device, comprise frame and rack-mounted loopy moving device and be located at the pallet on loopy moving device, track along described loopy moving device in described frame is provided with the first station successively, the second station, the 3rd station and the 4th station, described the first station is provided with labelled antigen fluid filling pump device, described the second station is provided with cleaning fluid fluid filling pump device, described the 3rd station is provided with and extracts cleaning fluid device, described the 4th station is provided with to put exempts from measuring device, described pallet is provided with regularly arranged multiple reagent bottle slots, the application of sample syringe needle of described labelled antigen fluid filling pump device, the application of sample syringe needle of cleaning fluid fluid filling pump device, extract the imbibition syringe needle of cleaning fluid device and put the detection syringe needle of exempting from measuring device and be arranged on the top of described pallet reagent bottle slot and quantity and arrange all corresponding with the reagent bottle slot of described pallet, the application of sample syringe needle of the application of sample syringe needle of described labelled antigen fluid filling pump device and cleaning fluid fluid filling pump device is separately fixed in the first station needle-carrier and the second station needle-carrier, the imbibition syringe needle of described extraction cleaning fluid device is arranged in the 3rd station needle-carrier, described the 3rd station needle-carrier is arranged in described frame by elevating mechanism, the described detection syringe needle of exempting from measuring device of putting is fixed in the 4th station needle-carrier, on described the 4th station, be also provided with the lifting body of the track below that is arranged on described loopy moving device, it is all corresponding with described pallet reagent bottle slot with quantity that the push rod of described lifting body is arranged on below and the position of described pallet reagent bottle slot, described pallet reagent bottle slot bottom is provided with the through hole corresponding with described push rod size position, in described frame, be also provided with heating arrangement and temperature inductor, described temperature inductor is arranged on the below of described pallet, described frame is provided with the outer cover of the whole frame of sealing outward.
Described outer cover is lead glass outer cover.
Described pallet is provided with ten linearly evenly distributed reagent bottle slots, the application of sample syringe needle of described labelled antigen fluid filling pump device, the application of sample syringe needle of cleaning fluid fluid filling pump device, extracts the imbibition syringe needle of cleaning fluid device and puts that to exempt from the detection syringe needle of measuring device all corresponding with reagent bottle slot quantity and arrangement on described pallet.
Owing to adopting said structure, the utility model is simple in structure, practical, simple to operate, and whole application of samples that can solve the coated method experiment of radio-immunity test tube are washed and taken out testing process.And this to install disposable amount detection many, the coated method experiment of radio-immunity test tube that is applicable to big-and-middle-sized hospital detects.Because be provided with heating arrangement, need not reagent bottle be taken out and put into incubator incubation again, therefore can save the plenty of time, increase work efficiency, the application of sample experiment of the different heated culture temperatures of simultaneous adaptation and the coated method of the radio-immunity test tube of differential responses time.The machine adopts servo-drive system, and not only application of sample is accurate, and adjustable application of sample speed; greatly reduce the application of sample time and reduce personal error; for hospital, can be patient report is provided as early as possible, because this installation cost is low; therefore also can be patient's cost saving and time greatly; lead glass outer cover can effectively protect the radiation of labelled antigen, and by automatic sample, operating personnel can be away from radiation area simultaneously; not only greatly reduce operating personnel's labour intensity, also can effectively protect operating personnel.
Brief description of the drawings
Fig. 1 is structural representation of the present utility model.
Fig. 2 is vertical view of the present utility model.
Embodiment
Below in conjunction with accompanying drawing, further describe the embodiment of this patent.
As shown in Figure 1, 2, the coated method of a kind of test tube is put and is exempted from instrument automatic cycle sample adding device, comprise frame and rack-mounted control section, loopy moving device 1 and be located at the pallet 8 on loopy moving device 1, the input touch-screen that control section comprises controller and controller is set, touch-screen can be realized man-machine conversation.In this example, loopy moving device 1 is by two horizontal servo moving systems (12, 13) and two servo longitudinal moving systems (11, 14) form, the track of described horizontal servo moving system and servo longitudinal moving system successively head and the tail connects and composes a cyclic track, thereby horizontal servo moving system and servo longitudinal moving system all drive the push pedal that is arranged on described track below to move promotion setting pallet 8 in orbit by servomotor, in described frame, be provided with successively the first station 2 along the track of described loopy moving device 1, the second station 3, the 3rd station 4 and the 4th station 5, described frame is equipped with optoelectronic switch entering each work bit position, described the first station 2 is provided with labelled antigen fluid filling pump device 21, described the second station 3 is provided with cleaning fluid fluid filling pump device 31, described the 3rd station 4 is provided with and extracts cleaning fluid device 41, described the 4th station 5 is provided with to put exempts from measuring device, described pallet 8 is provided with regularly arranged multiple reagent bottle slots, reagent bottle 7 is arranged in reagent bottle slot, the application of sample syringe needle 23 of described labelled antigen fluid filling pump device 21, the application of sample syringe needle 33 of cleaning fluid fluid filling pump device 31, extract the imbibition syringe needle 43 of cleaning fluid device 41 and put the detection syringe needle 52 of exempting from measuring device 5 and be arranged on the top of described pallet reagent bottle slot and quantity and arrange all corresponding with the reagent bottle slot of described pallet 8, while making work, all reagent bottles on a pallet 8 are operated simultaneously, the application of sample syringe needle 33 of the application of sample syringe needle 23 of described labelled antigen fluid filling pump device 21 and cleaning fluid fluid filling pump device 31 is separately fixed in the first station needle-carrier 22 and the second station needle-carrier 32, the first station needle-carrier 22 and the second station needle-carrier 32 are fixed in frame, the imbibition syringe needle 43 of described extraction cleaning fluid device 41 is arranged in the 3rd station needle-carrier 42, described the 3rd station needle-carrier 42 is arranged in frame by elevating mechanism, described elevating mechanism comprises the servomotor that screw rod 44 and lead-screw 44 move up and down, the described detection syringe needle 52 of exempting from measuring device of putting is fixed in the 4th station needle-carrier 51, on described the 4th station 5, be also provided with the lifting body 6 of the track below that is arranged on described loopy moving device 1, described lifting body 6 comprises multiple push rods 61, the supporter 62 of fixed mandril 61 and the servomotor that drives supporter 62 to move up and down, it is all corresponding with described pallet reagent bottle slot with quantity that the push rod 61 of described lifting body 6 is arranged on below and the position of described pallet reagent bottle slot, upwards jacking of push rod 61 when work, by reagent bottle 7 jack-up from the bottom up, make to detect syringe needle 52 and enter the interior detection of reagent bottle 7, in described frame, be also provided with heating arrangement 9 and temperature inductor, described temperature inductor is arranged on the below of described pallet 8, described frame is provided with the outer cover 10 of the whole frame of sealing outward, described outer cover 10 is lead glass outer cover, described pallet is provided with ten reagent bottle slots and linearly evenly distributed, the application of sample syringe needle of described labelled antigen fluid filling pump device, the application of sample syringe needle of cleaning fluid fluid filling pump device, extract the imbibition syringe needle of cleaning fluid device and put that to exempt from the detection syringe needle of measuring device all corresponding with arrangement with the reagent bottle slot quantity on described pallet.
When work: open outer cover 10, the reagent bottle 7 that adds sample is put under the reagent bottle slot that pallet 8(pallet 8 arranges with the aperture corresponding with lifting body 6 push rods 61.
Open Local Switch, heating arrangement 9 starts, and starts heating.
Carry out setting parameter by touch-screen: (1) sets application of sample number; (2) set labelled antigen application of sample dosage (ml); (3) set cleaning fluid application of sample dosage; (4) set wash number; (5) set the reaction time; (6) set temperature of reaction; (7) the setting measurement time.
Starting switch after setting completes.When temperature of reaction reaches after design temperature, loopy moving device 1 is worked, drive pallet 8 to enter the first station 2, after optoelectronic switch detects that pallet 8 enters, loopy moving device 1 quits work, simultaneously labelled antigen fluid filling pump device 21 is worked, to the label operation of antigen of all reagent bottles in pallet 8 simultaneously.After the operation of antigen of labelling completes, and reach after the reaction time of setting, loopy moving device 1 works on, and enters successively the second station, the 3rd station and the 4th station, completes the application of sample number of setting, completes experiment all.
Claims (3)
1. the coated method of test tube is put and is exempted from instrument automatic cycle sample adding device, comprise frame and rack-mounted loopy moving device and be located at the pallet on loopy moving device, it is characterized in that: the track along described loopy moving device in described frame is provided with the first station successively, the second station, the 3rd station and the 4th station, described the first station is provided with labelled antigen fluid filling pump device, described the second station is provided with cleaning fluid fluid filling pump device, described the 3rd station is provided with and extracts cleaning fluid device, described the 4th station is provided with to put exempts from measuring device, described pallet is provided with regularly arranged multiple reagent bottle slots, the application of sample syringe needle of described labelled antigen fluid filling pump device, the application of sample syringe needle of cleaning fluid fluid filling pump device, extract the imbibition syringe needle of cleaning fluid device and put the detection syringe needle of exempting from measuring device and be arranged on the top of described pallet reagent bottle slot and quantity and arrange all corresponding with the reagent bottle slot of described pallet, the application of sample syringe needle of the application of sample syringe needle of described labelled antigen fluid filling pump device and cleaning fluid fluid filling pump device is separately fixed in the first station needle-carrier and the second station needle-carrier, the imbibition syringe needle of described extraction cleaning fluid device is arranged in the 3rd station needle-carrier, described the 3rd station needle-carrier is arranged in described frame by elevating mechanism, the described detection syringe needle of exempting from measuring device of putting is fixed in the 4th station needle-carrier, on described the 4th station, be also provided with the lifting body of the track below that is arranged on described loopy moving device, it is all corresponding with described pallet reagent bottle slot with quantity that the push rod of described lifting body is arranged on below and the position of described pallet reagent bottle slot, described pallet reagent bottle slot bottom is provided with the through hole corresponding with described push rod size position, in described frame, be also provided with heating arrangement and temperature inductor, described temperature inductor is arranged on the below of described pallet, described frame is provided with the outer cover of the whole frame of sealing outward.
2. the coated method of test tube according to claim 1 is put and is exempted from instrument automatic cycle sample adding device, it is characterized in that: described outer cover is lead glass outer cover.
3. the coated method of test tube according to claim 1 is put and is exempted from instrument automatic cycle sample adding device, it is characterized in that: described pallet is provided with ten linearly evenly distributed reagent bottle slots, the application of sample syringe needle of described labelled antigen fluid filling pump device, the application of sample syringe needle of cleaning fluid fluid filling pump device, extract the imbibition syringe needle of cleaning fluid device and put that to exempt from the detection syringe needle of measuring device all corresponding with reagent bottle slot quantity and arrangement on described pallet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420050917.8U CN203672885U (en) | 2014-01-26 | 2014-01-26 | Automatic circulation sample loading device of test tube coating method radioimmunoassay analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420050917.8U CN203672885U (en) | 2014-01-26 | 2014-01-26 | Automatic circulation sample loading device of test tube coating method radioimmunoassay analyzer |
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| Publication Number | Publication Date |
|---|---|
| CN203672885U true CN203672885U (en) | 2014-06-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201420050917.8U Expired - Fee Related CN203672885U (en) | 2014-01-26 | 2014-01-26 | Automatic circulation sample loading device of test tube coating method radioimmunoassay analyzer |
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| CN (1) | CN203672885U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109696346A (en) * | 2017-10-20 | 2019-04-30 | 北京莱伯泰科仪器股份有限公司 | Isotope front processor |
| CN112578136A (en) * | 2020-12-30 | 2021-03-30 | 刘华 | Incubation tank and mobile incubation method |
-
2014
- 2014-01-26 CN CN201420050917.8U patent/CN203672885U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109696346A (en) * | 2017-10-20 | 2019-04-30 | 北京莱伯泰科仪器股份有限公司 | Isotope front processor |
| CN109696346B (en) * | 2017-10-20 | 2023-10-13 | 莱伯泰科(天津)科技有限公司 | Isotope pretreatment device |
| CN112578136A (en) * | 2020-12-30 | 2021-03-30 | 刘华 | Incubation tank and mobile incubation method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140625 Termination date: 20160126 |
|
| EXPY | Termination of patent right or utility model |